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Results for "11c pib": 18 found

Assessment of Deep Learning Models for 3D Dose Prediction in Prostate Cancer SIB-IMRT Using MR-Linac

Authors: Hao-Wen Cheng, Jonathan G. Li, Chihray Liu, Wen-Chih Tseng, Guanghua Yan

Affiliation: University of Florida

Abstract Preview: Purpose: This study develops and evaluates deep learning (DL) models for predicting 3D dose distributions in simultaneous integrated boost (SIB) prostate cancer treatment using the Elekta Unity MR-Lin...

Clinically Ready Simulation Package for Monitoring Gamma Hotspot Emission, and Detection in Patient Anatomy

Authors: Ananta Raj Chalise, Matthias K Gobbert, Zhuoran Jiang, Sina Mossahebi, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma, Jie Zhang

Affiliation: University of Maryland School of Medicine, University of Maryland Baltimore County, University of Maryland, Baltimore County, Stanford University, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc

Abstract Preview: Purpose: Prompt gamma (PG) imaging is a promising modality for proton dose verification. Currently, there is a lack of effective tool to investigate the PG emission during proton therapy and optimize ...

Clinically Tenable Lung Dose Estimates in Y-90 Radioembolization from Truncated Maa-SPECT/CT with Unknown Lung Mass

Authors: Dan Giardina, John Karageorgiou, Chris Malone, Naganathan Mani, Allan Thomas

Affiliation: Washington University School of Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine

Abstract Preview: Purpose: Relative to planar imaging, MAA-SPECT/CT offers more reliable lung shunt fraction (LSF) and lung mean dose (LMD) estimates in 90Y radioembolization. But lung truncation in SPECT/CT can limit ...

Correlated Pharmacokinetic Models in Targeted Alpha Therapy

Authors: Lars R Furenlid, Chiao Huang, Matthew A. Kupinski, Brian W. Miller

Affiliation: University of Arizona, Departments of Radiation Oncology and Medical Imaging, University of Arizona

Abstract Preview: Purpose: To sample correlated k-constants in tissue-compartment model for pharmacokinetic study in targeted alpha therapy.
Methods: This work simulated the biodistribution of PSMA-11 tracers labele...

Development of Foundation Model for Analysis of Prostate Cancer with Mpmri

Authors: Ahmad Algohary, Adrian Breto, Quadre Emery, Radka Stoyanova

Affiliation: University of Miami, Department of Radiation Oncology, University of Miami

Abstract Preview: Purpose:
To develop a foundation model (U-Found) for multiparametric MRI (mpMRI) of the prostate by using self-supervised learning to prove the feasibility of a prostate-oriented foundation model u...

Development of a Cadmium Zinc Telluride (CdZnTe) Detector-Based Neutron Imaging System

Authors: Soo Hyun Byun, Troy Farncombe, Edcer Jerecho DC Laguda

Affiliation: McMaster University

Abstract Preview: Purpose: We present the adaptation of a Cadmium Zinc Telluride (CdZnTe) detector, initially designed for SPECT-MR applications, to neutron imaging. This study explores a novel technique that utilizes ...

Dosimetric Impact of Target Coverage with Inter-Fraction Patient Yaw Setup Error in IMRT/VMAT Prostate Cancer Radiotherapy

Authors: Min Su

Affiliation: Mount Sinai School of Medicine

Abstract Preview: Purpose: To evaluate dosimetric impact of patient setup yaw error to target coverage for pelvis/prostate radiation external beam IMRT-VMAT treatment.
Methods: 9 Pelvis/prostate IMRT-VMAT treatment ...

Evaluating Longitudinal Amyloid Burden Related to Alzheimer’s Disease When Transitioning between PET β-Amyloid Radiotracers

Authors: Brecca Bettcher, Tobey J Betthauser, Bradley T Christian, Sterling Johnson, Lisette LeMerise, Max McLachlan, Andrew McVea, Dhanabalan Murali, Ali Pirasteh, Matthew Zammit

Affiliation: University of Wisconsin-Madison School of Medicine and Public Health and Waisman Center

Abstract Preview: Purpose: The radiotracer [18F]NAV4694 is a desirable alternative to [11C]PiB for measuring amyloid neuropathology related to Alzheimer’s disease (AD), possessing similar imaging characteristics and fa...

Evaluation of Lead Glasses Efficiency in Reducing Eye Radiation Exposure during Angiography Using Optically Stimulated Luminescence Dosimeters

Authors: Yu-Ying Lin, Yu Chen Shen

Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou

Abstract Preview: Purpose: This study evaluates the protective efficiency of lead glasses against radiation exposure to the eyes during angiography using optically stimulated luminescence dosimeters (OSLDs).
Methods...

Exploring the Compatibility of VMAT and Respiratory Beam Gating on MR-Linac: A Proof-of-Concept Study

Authors: Caiden Atienza, Pim T. S. Borman, Martin F. Fast, Daniel E. Hyer, Bas W. Raaymakers, Jeffrey E. Snyder, Prescilla Uijtewaal, Peter Woodhead

Affiliation: Department of Radiotherapy, University Medical Center Utrecht, Yale New Haven Health, University of Iowa

Abstract Preview: Purpose:
On conventional C-arm linacs, VMAT is the preferred delivery modality due to its superior efficiency and highly conformal dose distributions. MR-linacs offer superior soft-tissue imaging t...

Machine Learning Knowledge Based Planning Model for Hypo Fractionated Prostate/Prostate Lymph Nodes Treatments

Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang

Affiliation: FCCC at Temple University Hospital

Abstract Preview: Purpose: To evaluate the performance of KBP models for hypo-fractionated prostate and pelvic lymph nodes (LN) VMAT plans.
Methods: A KBP model (TUH KBP) was developed in Eclipse treatment planning ...

Personalized and Automated Head & Neck Radiotherapy Planning with AI-Guided Optimization

Authors: Michael Bowers, Patrik Brodin, Madhur Garg, Rafi Kabarriti, William P. Martin, Todd R. McNutt, Julie Shade, Wolfgang A. Tomé, Christian Velten

Affiliation: Johns Hopkins University, Oncospace, Inc., Montefiore Medical Center

Abstract Preview: Purpose: Development of an automated planning tool utilizing AI generated patient-specific dose-volume histogram predictions for rapid H&N plan generation.
Methods: Planning best-practices were dev...

Poisson Decay in Pharmacokinetics with Imaging in Targeted Alpha Therapy

Authors: Lars R Furenlid, Chiao Huang, Matthew A. Kupinski, Brian W. Miller

Affiliation: University of Arizona, Departments of Radiation Oncology and Medical Imaging, University of Arizona

Abstract Preview: Purpose: To sample random numbers of decay of radiotracers in a pharmacokinetic compartment model for Monte-Carlo simulation of imaging in targeted alpha therapy.
Methods: Time-activity curves (TAC...

Post-Implant Dosimetry (PID) between 1D and 2D Cs-131 Seed Models for Post-Op Cavities in Recurrent GBM Patients

Authors: Cindy Pham, Anurag Sharma, John Starner, Ching-Ling Teng, Michael A. Trager, Gabriella Wernicke

Affiliation: Northwell, Northwell Health, Radiation Medicine, Northwell Health

Abstract Preview: Purpose: Precisely identifying orientation of implanted seeds on post-implant CTs is challenging. This research addresses the dosimetric uncertainties stemming from uncertainties in identifying seed o...

Radiobiological Calculations of Daily Doses Using Pseudo CT (pCT)

Authors: Chloe DiTusa, Panayiotis Mavroidis, Christopher W. Schneider, Sotirios Stathakis

Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center, University of North Carolina

Abstract Preview: Purpose:
To calculate radiobiological metrics of daily dose delivered for head and neck (HN) patients using the daily cone beam CT (CBCT) to generate a pseudo CT (pCT). Moreover, this work compares...

Reducing Distal-Edge Toxicity in Breast Proton Therapy Via LETd and Track-End Optimization

Authors: Matthew Case, Richard Castillo, Sunil Dutta, Edgar Gelover, Katja M. Langen, Alexander Stanforth, Mingyao Zhu

Affiliation: Emory University

Abstract Preview: Purpose: To evaluate the application of LETd and track-end (TE) objective functions during the optimization of breast proton therapy plans to decrease the risk of lung toxicity and rib fractures.
M...

Streamlining Hippocampal-Sparing Whole-Brain VMAT Planning: Enhancing Efficiency and Plan Quality with an Automated Workflow

Authors: Eric C. Ford, Yulun He, Minsun Kim, Dustin Melancon, Juergen Meyer, Dong Joo Rhee, Yinghua Tao

Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, MD Anderson Cancer Center, University of Washington

Abstract Preview: Purpose: To develop and evaluate an automated-planning technique capable of generating high-quality treatment plans for hippocampal-sparing-whole-brain radiation therapy.
Methods: An auto-planning ...

Ultrafast Proton Delivery with Pin Ridge Filters (pRFs): A Novel Approach for Motion Management in Proton Therapy

Authors: Zachary Diamond, Pretesh Patel, Sibo Tian, Yinan Wang, Xiaofeng Yang, David Yu, Ahmal Jawad Zafar, Jun Zhou

Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Active breath-hold techniques effectively mitigate respiratory motion but poses challenges for patients who are unable to tolerate the procedure. Conventional planning relies on multiple ener...