Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens
Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI
Abstract Preview: Purpose:
Low-Tesla MRI (0.23T Panorama MR Scanner, Philips) has been used for tumor progression during proton therapy treatments, and for initial contouring in addition to diagnostic MRI. The pulse...
Authors: John Paul Ortiz Bustillo, Elette Engels, Elrick T. Inocencio, Michael Lerch, Julia Rebecca D Posadas, Anatoly Rosenfeld, Kiarn Roughley, Moeava Tehei, Gordon Wallace, Danielle Warren, Vincent de Rover
Affiliation: Centre for Medical Radiation Physics, University of Wollongong Australia, Department of Radiology, University of the Philippines- Philippine General Hospital, Intelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong Australia, Centre for Medical Radiation Physics, University of Wollongong, Intelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong, University of the Philippines Manila; Centre for Medical Radiation Physics, University of Wollongong Australia
Abstract Preview: Purpose: To compare the biological response through cell viability assay and fluorescence imaging of 3D bioprinted brain cancer (glioma) constructs relative to 2D monolayer and 3D spheroid culture for...
Authors: Brett Bocian, Nesrin Dogan, John C. Ford, Alan Pollack, Ryder Marshall Schmidt, Junwei Shi, Jorge D Vega
Affiliation: University of Miami, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: X-ray fluorescence computed tomography (XFCT) is an emerging molecular imaging modality gaining attention in cancer theranostics with high-Z metal nanoparticles (MNPs). While XFCT has been de...
Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Bohong Huang, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Four-dimensional cone-beam computed tomography (4D-CBCT) is critical in image-guided radiotherapy (IGRT) for visualizing tumor motion. However, sparse projection sampling often introduces sev...
Authors: Jeremy S. Bredfeldt, Cindy I. Hancox, Arianna Liles, Alex Marques, Usha Tedrow
Affiliation: Department of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School
Abstract Preview: Purpose: Ventricular tachycardia (VT) can be treated using cardiac radioablation. 4DCT simulation is commonly used, however, contrast injection timing is challenging. This study aimed to develop a pro...
Authors: Sean L. Berry, Hsiang-Chi Kuo, Seng Boh Gary Lim, Ingrid Valencia Lozano, Laszlo Voros
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
To quantify the impact of target degradation on 6FFF beam output by analyzing the output trends and adjustment frequencies at our clinic on a flattening filter-free (6FFF) and a flattened ...
Authors: Fu-Xiong Chang, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Nancy Y Lee, Chih-Hsun Lin, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Pingfang Tsai, Shouyi Wei, Irini Yacoub, Yunjie Yang, Ajay Zheng, Jun Zhou
Affiliation: New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Liverage Biomedical Inc., Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Institute of Physics, Academia Sinica
Abstract Preview: Purpose: FLASH therapy presents an opportunity to alter the radiotherapy paradigm and significantly enhancing normal organ protection while maintaining the effectiveness of tumor control. The temporal...
Authors: Christina Brunnquell, Daniel Vergara, Joseph Everett Wishart
Affiliation: University of Minnesota, University of Washington
Abstract Preview: Purpose: To propose and validate a correction to the bandwidth difference method presented in Task Group Report No. 325 for quantifying static magnetic field homogeneity (ΔB0).
Methods: A clarifica...
Authors: Steven DiBiase, Gurtej S. Gill, Haohua Billy Huang, Nicholas J. Lavini, Luxshan Shanmugarajah, Salar Souri, Samantha Wong
Affiliation: Stony Brook University, Northwell Health, Cornell University, NewYork-Presbyterian, New York-Presbyterian
Abstract Preview: Purpose: Clinical applications of deep learning-based algorithms have come to the radiation oncology field as organ at risk (OAR) auto contouring programs. We evaluated two of these algorithms’ (Radfo...
Authors: Steve Braunstein, Yannet Interian, Hui Lin, Bo Liu, Janine Lupo, Olivier Morin, Benedict Neo
Affiliation: Radiation Oncology, University of California San Francisco, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, University of California San Francisco, Department of Data Science, University of San Francisco, University of San Francisco
Abstract Preview: Purpose: Large Language Models (LLMs) demonstrate strong general text comprehension but remain limited in oncology due to insufficient contextual alignment. We pilot embedding alignment through radiol...
Authors: Mohamed Eldib, Adam Mahl, Moyed Miften, Rachel Petragallo, Kelly L. Stuhr
Affiliation: University of Colorado - Anschutz Medical Campus, University of Colorado School of Medicine, University of Colorado Denver, Department of Radiation Oncology, University of Colorado
Abstract Preview: Purpose: To compare electron beam dose calculations performed manually with those computed using the Macro Monte Carlo simulation for standard fields on both phantom and patient setups, with the aim o...
Authors: Aaron Conard, Victoria Croog, Marie Gurka, Lan Lin
Affiliation: Johns Hopkins University
Abstract Preview: Purpose:
This study evaluates the utility of the Active Breathing Coordinator (ABC) and Surface Guided Radiation Therapy (SGRT) techniques in implementing Deep Inspiration Breath Hold (DIBH) for le...
Authors: Nebi Demez, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Nishan Shrestha
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: Treatment plans on the ViewRay MRIdian are often planned with the target placed off isocenter due to the proximity of the bore to the patient, allowing for limited shifts. This is especially ...
Authors: Jamie s Baker, Sam Beddar, Mahsa Dehghanpour, Ariel MT Hoang, Emma Holliday, Rachael M. Martin Paulpeter, Joshua S. Niedzielski, Luis Augusto Perles, Josie S Ruzek, Gabriel O. Sawakuchi
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, niversity of Texas MD Anderson Cancer Center School of Health Professions, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, University of Texas MD Anderson Cancer Center School of Health Professions
Abstract Preview: Purpose: This study aims to evaluate the dosimetric impact on organs at risk (OAR) of small versus large spot sizes when treating pelvic cancer patients with pencil beam scanning (PBS) proton therapy....
Authors: Jenghwa Chang, Kuan Huang, Lyu Huang, Jason Lima, Jian Liu, Farzin Motamedi
Affiliation: Northwell, Department of Computer Science and Technology, Kean University, Physics and Astronomy, Hofstra University, Hofstra University Medical Physics Program
Abstract Preview: Title: A Deep Learning Approach to the Prediction of Gamma Passing Rates in VMAT Radiotherapy Plans for Adaptive Treatment.
Purpose: This study aims to develop a deep learning algorithm to predict ...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Nicholas Lowther, Daniel Morf, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Womens Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: A challenge for dual energy CBCT is that noise and residual errors in material decomposition steps can become amplified when forming low energy, high contrast virtual mono-energetic images (V...
Authors: Suman Gautam, Tianjun Ma, William Song
Affiliation: Virginia Commonwealth University
Abstract Preview: Purpose: We propose an artificial intelligence (AI)-based method to rapidly predict the patient-specific quality assurance (PSQA) results for magnetic resonance (MR)-guided online adaptive radiation th...
Authors: Yu Chang, Mei Chen
Affiliation: Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Abstract Preview: Purpose: Spot weights optimization, as a critical step in the proton therapy, is often time-consuming and labor-intensive. Deep learning, with its powerful learning and computational efficiency, can e...
Authors: Travis James McCaw, Ravi Patel, Abdelhamid Saoudi, Joseph Shields
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, UPMC
Abstract Preview: Purpose: The current treatment approach for Lu-177-based radiopharmaceutical therapy involves multiple administrations, each delivering a constant activity of 200 mCi. This study evaluates whether the...
Authors: Chin-Cheng Chen, Chia-Ho Hua, Christopher J. Kutyreff, Thomas E. Merchant
Affiliation: St. Jude Children's Research Hospital
Abstract Preview: Purpose: A dosimetric study was conducted to determine the optimal field parameters for a commercially available small-field applicator (SFA) used in spot-scanning proton stereotactic radiosurgery, pa...
Authors: Jie Deng, Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Based on a 3D pre-treatment MRI scan, we developed DREME-MR to jointly reconstruct the reference patient anatomy and a data-driven, patient-specific cardiorespiratory motion model. Via a moti...
Authors: Yidong Yang, Haolin Zhan
Affiliation: Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China
Abstract Preview: Purpose: To develop a fast low-dose method for beam blocker-based CBCT scatter correction and evaluate image quality in phantom study.
Methods: The full number of scatter projections were collected...
Authors: Emi Ai Eastman, Christina Lee, Xinhua Li, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose:
This study aimed to retrospectively evaluate dose reduction efforts in past five years using acquisition-level data and to compare the results with ACR achievable dose (AD) and dose refere...
Authors: Bryan Bednarz, Malick Bio Idrissou, Campbell Haasch, Reinier Hernandez
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin–Madison, University of Wisconsin - Madison
Abstract Preview: Purpose: Quantitative optical imaging is a powerful tool in murine models for assessing tumor growth and metastatic spread using bioluminescence imaging (BLI) and for detecting radiopharmaceutical upt...
Authors: Wenfeng He, Tian Liu, Pretesh Patel, Richard L.J. Qiu, Keyur Shah, Tonghe Wang, Xiaofeng Yang, Chulong Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Emory University, Medical Physics Graduate Program, Duke Kunshan University, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: This study introduces a tracking-free approach to reconstruct 3D ultrasound (US) volumes from 2D freehand US scans. By eliminating the reliance on external tracking systems, this method aims ...
Authors: Timothy J Allen, David A. Sterling
Affiliation: University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: Treatment planning for the Venezia HDR brachytherapy applicator is often performed using inverse planning tools such as IPSA or HIPO. However, there are planners who are either unfamiliar wit...
Authors: Jie Liu
Affiliation: Inova Health System
Abstract Preview: Purpose:
The respiratory signal commonly acquired by using external surrogates or detecting the diaphragm position only represents the phase information and has poor correlation with the tumor moti...
Authors: Edward D. Brandner, Weihua Fu, M. Saiful Huq, Ronald John Lalonde, Kiran Mehta, Hima Bindu Musunuru, Yongqian Zhang
Affiliation: UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pittsburgh School of Medicine and UPMC Hillman CancerCenter
Abstract Preview: Purpose: Treatment of diffuse and extensive involvement of the skull by malignancy presents a difficult challenge for radiation therapy. This study reports preliminary experience of a modified volumet...
Authors: Matthew S Brown, Joshua Genender, John M. Hoffman, Gabriel Melendez-Corres, Muhammad W. Wahi-Anwar
Affiliation: David Geffen School of Medicine at UCLA, UCLA Department of Radiology
Abstract Preview: Purpose: Renal lesions are evaluated using scoring systems based on visual assessments and manual measurements. The purpose of this work is to develop a multi-agent system for automated anatomic landm...
Authors: Louis Archambault, Luc Beaulieu, Alexis Horik, Sajjad Ahmad Khan
Affiliation: Département de Physique, de Génie Physique et D'optique, et Centre de Recherche sur le Cancer, Université Laval, Département de physique, de génie physique et d'optique, Université Laval
Abstract Preview: Purpose: This study presents a novel 2D scintillation dosimeter leveraging long scintillating fibers for quality assurance (QA) in radiotherapy. The primary goal is to optimize critical parameters suc...
Authors: Reza Farjam, Russell K Hales, Seth Jayawardane, Todd R. McNutt, Mohammad Rezaee, Ehsan Tajikmansoury, K. Ranh Voong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins School of Medicine
Abstract Preview: Purpose: This study presents a novel cost-effective customizable 3D-printed phantom developed for end-to-end treatment verification and image-quality assessment for thoracic applications.
Methods: ...
Authors: Ahad Ollah Ezzati, Yile Fang, Xiaoyu Hu, Xun Jia, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University
Abstract Preview: Purpose: With breast cancer being one of the most prevalent cancers, regular screening is an effective strategy to mitigate the risk of malignancy. However, conventional energy-integrating detector (E...
Authors: Hongyu An, Phillip Cuculich, H Michael Gach, Yao Hao, Trevor McKeown, Clifford Robinson, Yuhao Wang, Deshan Yang
Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, Duke University, Department of Radiation Oncology, Duke University, Washington University in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis
Abstract Preview: Purpose: Cardiorespiratory motion management is crucial in stereotactic arrhythmia radiotherapy to define target margins and minimize cardiac toxicity. While respiratory 4DCT (r4DCT) images can infer ...
Authors: Chuan He, Anh H. Le, Iris Z. Wang
Affiliation: Roswell Park Comprehensive Cancer Center, Cedars-Sinai
Abstract Preview: Purpose: To develop a non-measured and DVH-based (NMDB) IMRT QA framework integrating machine learning (ML) to classify lung SBRT VMAT plans prone to delivery errors
Methods: 560 Eclipse AcurosXB l...
Authors: James Robert Castle, Joshua Misa, Damodar Pokhrel, William St. Clair
Affiliation: University of Kentucky, Department of Radiation Medicine
Abstract Preview: Purpose: We propose a novel methodology for lattice deployment in spatially fractionated radiotherapy (SFRT), using principal component analysis (PCA) to improve sphere packing within the tumor. Impro...
Authors: Ming Su, Yuenan Nancy Wang
Affiliation: Northeastern University, Hartford Healthcare
Abstract Preview: Purpose: High Z elements such as lead are often used to protect critical structures in clinical radiotherapy. Nanoparticles have different properties than bulk materials. We proposed a polymer matrix ...
Authors: Jaryd Ricardo Christie, Anthony J. Doemer, William T. Hrinivich, Junghoon Lee, Calin Reamy, Kundan S Thind
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, Henry Ford Health
Abstract Preview: Purpose: To develop and validate an open-source Python package for fast, widely compatible, and user-friendly photon dose calculation algorithm through comparisons with clinical treatment planning sys...
Authors: Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Joseph Shields, Christopher Tyerech
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pennsylvania, UPMC
Abstract Preview: Purpose: HyperSight is a new platform for image-guided radiation therapy, offering advanced reconstruction algorithms, a large field-of-view, and rapid acquisition times. To validate the performance o...
Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Lewei Zhao
Affiliation: Department of Radiation Oncology, Stanford University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital
Abstract Preview: Purpose: This study quantitatively evaluates the interplay effect in intensity-modulated proton therapy (IMPT) for lung cancer stereotactic body radiotherapy (SBRT) using two different machine deliver...
Authors: Ivan L. Cordrey, Dharmin D. Desai
Affiliation: Cumberland Medical Center - Cancer Center, Varian Advanced Oncology Solutions
Abstract Preview: Purpose: For larger PTVs, VMAT optimizations performed within Eclipse often generate SRS plans with widely scattered hotspots distributed around the inner edge of the PTV – the “ring of fire.” This pr...
Authors: Yuli Lu, Chendong Ni, Cheng Qian, Kun Qian, Weiwei Sang, Chunhao Wang, Fan Xia, Zhenyu Yang, Fang-Fang Yin, Rihui Zhang, Haiming Zhu
Affiliation: Jiahui International Hospital, Radiation Oncology, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: To develop a radiomic quantification framework to evaluate the effects of radiomic image preprocessing hyperparameters (i.e., image resampling and discretization) on texture characterization ...
Authors: Yongrui Bai, Xuming Chen, Yong Liu, Xiumei Ma
Affiliation: Department of Radiation Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Abstract Preview: Purpose: Hematologic toxicity (HT) is a common complication in patients with cervical or endometrial cancer. This study aims to develop a precise predictive model for acute HT in patients with cervica...
Authors: Weiguo Lu, Jax Luo, Xiaoxue Qian, Hua-Chieh Shao, Guoping Xu, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Harvard Medical School
Abstract Preview: Purpose:
Semi-supervised segmentation leverages sparse annotation information to learn rich representations from combined labeled and label-less data for segmentation tasks. This study leverages th...
Authors: Rani Anne', Wenchao Cao, Yingxuan Chen, Wookjin Choi, Firas Mourtada, Yevgeniy Vinogradskiy
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: In-room mobile cone-beam CT (CBCT) is emerging to enhance high-dose-rate (HDR) brachytherapy workflow using on-demand imaging. However, metal artifacts from X-ray markers inside gynecological...
Authors: Neil A. Kirby, Parker New, Niko Papanikolaou, Holly Paschal, Karl H. Rasmussen, Daniel L. Saenz
Affiliation: UT Health San Antonio
Abstract Preview: Purpose: To simplify the traditional method of patient-specific skin collimation and improve the precision of electron radiotherapy treatment with a new surface conforming collimation system.
Metho...
Authors: David Brizel, Kyle J. Lafata, Jian-Guo Liu, Yvonne M Mowery, Yvonne M Mowery, William Paul Segars, Jack B Stevens
Affiliation: Department of Physics, Duke University, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh
Abstract Preview: Purpose: To develop a technique to quantify tumor topology using a unifying mathematical framework that integrates texture and morphology and to evaluate its feasibility as a prognostic biomarker for ...
Authors: Penghao Gao, Zejun Jiang
Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: Real-time tumor tracking can effectively compensate for the impact of respiratory motion on dose distribution. We propose a patient-specific external-internal correlation model driven by opti...
Authors: Stephen R. Bowen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Jing Sun, Jiajie Wang, Shouyi Wang, Faisal Yaseen, Xiaojing Zhu
Affiliation: Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Shanghai University of Electric Power, Fred Hutchinson Cancer Center, University of Texas at Arlington
Abstract Preview: Purpose: Accurate prediction of patient response to radiotherapy plays a crucial role in monitoring disease progression and assessing treatment efficacy, enabling clinicians to develop personalized th...
Authors: Zachary Buchwald, Chih-Wei Chang, Richard L.J. Qiu, Mojtaba Safari, Hui-Kuo Shu, Lisa Sudmeier, Xiaofeng Yang, David Yu, Xiaohan Yuan
Affiliation: Emory University and Winship Cancer Institute, Emory University, Georgia Institute of Technology, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: This study proposes a novel vision-language model (VLM) to predict survival outcomes in glioblastoma (GBM) patients. By integrating multimodal MRI data and clinical information, the proposed ...
Authors: Weigang Hu
Affiliation: Fudan University Shanghai Cancer Center
Abstract Preview: Purpose: The purpose of this study is to introduce a VQVAE-based framework that addresses the limitations of conventional dose prediction methods, which rely on fixed deep learning models that produce...
Authors: Hilary P Bagshaw, Mark K Buyyounouski, Cynthia Fu-Yu Chuang, Yu Gao, Dimitre Hristov, Lianli Liu, Lawrie Skinner, Lei Xing
Affiliation: Department of Radiation Oncology, Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose:
MR-guided radiation therapy has introduced a significant leap in cancer treatment by allowing adaptive treatment. The low-field MR-guided system predominantly uses the TrueFISP sequence, w...
Authors: Pradeep Bhetwal, Wookjin Choi, Adam Dicker, Rupesh Ghimire, Yingcui Jia, Lauren Nkwonta, Yevgeniy Vinogradskiy, Wentao Wang, Maria Werner-Wasik
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: Multi-disciplinary clinics are becoming standard of care for patients with lung cancer treated with SBRT. To improve clinical decision support in a multi-disciplinary clinic, it would be bene...
Authors: Giovanni Iacca, Gloria Miori, Laura Orsingher, Daniele Ravanelli, Annalisa Trianni
Affiliation: Department of Information Engineering and Computer Science, University of Trento, Medical Physics Department, S.Chiara Hospital, APSS
Abstract Preview: Purpose: This study aims to leverage artificial intelligence (AI) to predict and identify performance degradation in Digital Radiography (DR) systems, enabling proactive maintenance and minimizing cli...
Authors: Izabella L. Barreto, Benjamin Taylor Heggie, Stephanie M. Leon
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: 3D printing has the potential for producing materials useful for the imaging field. This work aims to identify absorption (attenuation coefficient) and material properties (effective atomic n...
Authors: Michael Caulfield, Ye Chen, Yoshihiro Ishi, Yasutoshi Kuriyama, Taeko Matsuura, Naoki Miyamoto, Taichi Murakami, Tomonori Uesugi, Kohei Yokokawa
Affiliation: Hokkaido University, Kyoto University, University of Alberta
Abstract Preview: Purpose: Protoacoustics has the potential for real-time and direct imaging of the Bragg peak. This study investigated the accuracy of the Bragg peak imaging based on the water phantom experiment at a ...
Authors: Emi Ai Eastman, Chao Guo, Christina Lee, Xinhua Li, Alexander W. Scott, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose:
Smoking is one of the risk factors for coronary artery disease. It is desirable to estimate the coronary artery calcification (CAC), a key biomarker for atherosclerosis and cardiovascular ...
Authors: Zachary Diamond, Pretesh Patel, Sibo Tian, Xiaofeng Yang, David Yu, Ahmal Jawad Zafar, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose:
We propose a method to optimize adaptive proton FLASH therapy (ADP-FLASH) using modularized pin-ridge filters (pRFs) by recycling module pins from the initial plan, reducing pRF adjustment...
Authors: Robert K Chin, Klea Hoxha, Erika Jank, Jesus Juarez, Eulanca Yuka Liu, Dylan P. O'Connell, X. Sharon Qi, Ricky R Savjani
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, Los Angeles, UCLA Radiation Oncology
Abstract Preview: Purpose:
Daily cone beam CT (CBCT) images are acquired prior to each radiotherapy treatment for verifying patient positioning. HyperSight is an advanced imaging solution that replaces standard CBCT...
Authors: Hassan Bagher-Ebadian, Indrin J. Chetty, Mohamed Elshaikh, Ahmed I Ghanem, Mohammad M. Ghassemi, Reza Khanmohammadi, Benjamin Movsas, Shayan Siddiqui, Kundan S Thind, Jawad Turfa
Affiliation: Michigan State University, Department of Radiation Oncology,Cedars-Sinai Medical Center, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health
Abstract Preview: Purpose: Extracting late radiotherapy-induced toxicities from free-text notes using natural language processing is complicated by negative symptom identification, computational demands, and data priva...
Authors: Silambarasan Anbumani, Nicolette O'Connell, Eenas A. Omari, Amanda Pan, Eric S. Paulson, Lindsay Puckett, Monica E. Shukla, Dan Thill, Jiaofeng Xu
Affiliation: Elekta Inc, Elekta Limited, Linac House, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Accurate electron density information from on-board imaging is essential for direct dose calculations in adaptive radiotherapy (ART). This study evaluates a deep learning model for thoracic s...
Authors: Zachary Buchwald, Chih-Wei Chang, Zach Eidex, Richard L.J. Qiu, Mojtaba Safari, Shansong Wang, Xiaofeng Yang, David Yu
Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: MRI offers excellent soft tissue contrast for diagnosis and treatment but suffers from long acquisition times, causing patient discomfort and motion artifacts. To accelerate MRI, supervised d...
Authors: Meixu Chen, Jing Wang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center
Abstract Preview: Purpose: Cancer treatment outcome prediction plays a pivotal role in guiding therapeutic decisions and optimizing patient care. Traditionally, binary prediction models have been widely used for risk s...
Authors: Ioannis Androulakis, Jérémy Godart, Mischa Hoogeman, Inger-Karine K. Kolkman-Deurloo, Remi A. Nout, Robin Straathof, Henrike Westerveld, Myra van Laar
Affiliation: Department of BioMechanical Engineering, Delft University of Technology, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam
Abstract Preview: Purpose:
In brachytherapy for gynaecological cancers using intracavitary applicators, implant reconstruction is commonly performed using applicator libraries. These libraries contain applicator geo...
Authors: Jie Hu, Zhengdong Jiang, Nan Li, Tie Lv, Yuqing Xia, Shouping Xu, Gaolong Zhang, Wei Zhao, Changyou Zhong
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Radiotherapy Department of Meizhou People’s Hospital (Huangtang Hospital), UT Health San Antonio, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, Peopleʼs Republic of China, Department of Radiation Oncology
Abstract Preview: Purpose: Patients usually undergo cone-beam computed tomography (CBCT) scans which are used for patient set-up before radiotherapy. However, the low image quality of CBCT hinders its use in adaptive r...
Authors: Harsh Arya, Yan Chang, Yujie Chi, Varghese Anto Chirayath, Joshua Rajan, Pan Zui
Affiliation: University of Texas at Arlington, Department of Physics, University of Texas at Arlington
Abstract Preview: Purpose: In targeted alpha therapy (TAT), absorbed dose rates can vary significantly spatially and temporally, impacting therapeutic efficacy as well as carcinogenic potential. This study reports the ...
Authors: Strahinja Stojadinovic, Robert Timmerman, Yulong Yan
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose: Radiosurgery for large (>10cc) arteriovenous malformations (AVMs) poses significant challenges due to increased risks of complications and lower obliteration rates. To mitigate toxicity, larg...
Authors: Yasin Abdulkadir, Justin Hink, James M. Lamb, Jack Neylon
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: Curation remains a significant barrier to the use of ‘big data’ radiotherapy planning databases of 100,000 patients or more. Anatomic site of treatment is an important stratification for almo...
Authors: Jingyun Chen, Yading Yuan
Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology
Abstract Preview: Purpose: To develop and evaluate the Scale-attention network (SANet) for automated pancreas segmentation on MR images.
Methods: To develop SANet, we extended the classic U-Net design with a dynamic...
Authors: Olivier Blasi, Eric Cameron, Brad K. Lofton
Affiliation: CAMP, Colorado Assn in Medical Phys (CAMP)
Abstract Preview: Purpose:
Magnetic Resonance (MR) imaging obtained from external centers for radiation therapy (RT) planning can suffer from suboptimal protocols and geometric distortions. These issues can require ...
Authors: Xiaolong Fu, Runping Hou, Md Tauhidul Islam, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine
Abstract Preview: Purpose: To introduce a novel schematic image representation of radiomics data, called OmicsMap, for high-performance deep radiomics analysis. OmicsMap transforms tabular radiomics data into an image ...
Authors: Ye Chen, Koki Kasamatsu, Taeko Matsuura, Taichi Murakami
Affiliation: Hokkaido University, National Institutes for Quantum Science and Technology (QST)
Abstract Preview: Purpose: In proton therapy, CT-based estimation of the stopping power ratio (SPR) is a significant source of range uncertainty. Protoacoustics have been developed to estimate the range in vivo, but fe...
Authors: Hao Gao, Xue Hong, Harold Li, Yuting Lin, Jufri Setianegara, Xin Tong, Chao Wang, Weijie Zhang, Ya-Nan Zhu
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Lattice radiotherapy (LATTICE) is a form of spatially fractionated radiation therapy (SFRT) designed to deliver high radiation doses to specific tumor regions (vertices) while sparing surroun...
Authors: Wenbo Gu, Chenhui Qiu, Ke Sheng, Liyan Sun, Weiyuan Sun, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiology, Stanford University, University of Pennsylvania, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, Stanford University,
Abstract Preview: Purpose:
The small animal radio-neuromodulation platform developed in our previous work utilized focused kV x-ray beams rotating and translating in predefined trajectories to irradiate small, mm si...
Authors: James R Duncan, Nikhat Fatima Mansoori, Allan Thomas
Affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine
Abstract Preview: Purpose: Collimation during fluoroscopically-guided interventions (FGIs) can not only reduce radiation exposure to patients and personnel but also improve image quality. Nonetheless, there are concern...
Authors: Sijuan Huang, Zi LIU, Jing MA, Xin Yang
Affiliation: Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, Guangdong, 510060, China
Abstract Preview: Purpose: To reduce the pressure of manual review of abnormal situations in manually/automatically delineated regions of interest (ROI), improve its accuracy and basis.
Methods: 220 radiotherapy pat...
Authors: Yile Fang, Leslie Lamb, Nathaniel David Mercaldo, Kai Yang
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: To quantitatively evaluate power-law exponent β as a potential image-based breast cancer risk factor.
Methods: Two groups of breast cancer screening cohorts (target vs. control, 20 sub...
Authors: Daming LI, Jinsen Xie, Zhe Zhang
Affiliation: Peking University Shenzhen Hospital Radiotherapy Department, School of Nuclear Science and Technology, University of South China
Abstract Preview: Purpose:
This study aims to investigate the feasibility of online dose measurement of the Trilogy linear accelerator output based on target current pulse signals.
Methods:
A data acquisition ...
Authors: Hideaki Hirashima, Haruo Inokuchi, Nobutaka Mukumoto, Naruki Murahashi, Mitsuhiro Nakamura, Megumi Nakao, Keiko Shibuya, Linna Zhang
Affiliation: Kyoto University, Osaka Metropolitan University
Abstract Preview: Purpose:
To transform the quality of 2D cine MR images acquired during online adaptive MR-guided radiotherapy (OA-MRgRT) by utilizing a conditional diffusion model to achieve image quality comparab...
Authors: Steve B. Jiang, Dan Nguyen, Chenyang Shen, Fan-Chi F. Su, Jiacheng Xie, Shunyu Yan, Daniel Yang, Ying Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Accurate delineation of treatment targets and organs-at-risk is crucial for radiotherapy. Despite significant progress in artificial intelligence (AI)-based automatic segmentation tools, effi...
Authors: Shaojie Chang, Thomas A. Foley, Hao Gong, Emily Koons, Shuai Leng, Cynthia H. McCollough, Eric E. Williamson
Affiliation: Mayo Clinic
Abstract Preview: Purpose: To enhance coronary CT angiography (cCTA) capabilities on conventional energy integrating detector CT (EID-CT) using artificial intelligence (AI). The AI framework incorporates high-resolutio...
Authors: Richard Lesieur, Olivia Magneson, David E. Solis, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: This study evaluates the deliverability and precision of multileaf collimator (MLC) positioning in treatment plans generated by two different Treatment Planning Systems (TPS), Monaco and Pinn...
Authors: Ivan L. Cordrey, Dharmin D. Desai, Ellis Lee Johnson
Affiliation: Cumberland Medical Center - Cancer Center, University of Kentucky, Varian Advanced Oncology Solutions
Abstract Preview: Purpose: HyperArc (HA) is known to produce a high quality SRS plan. Adding Surface Area Informed Optimization (SAIO) to HA has been shown to improve plan quality metrics R50% and the Conformality Inde...
Authors: Maria F. Chan, Seng Boh Gary Lim, Shih-Chi Lin, Dustin W. Lynch, Usman Mahmood, Jeonghoon Park
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To explore the feasibility of using GafChromic LD-V1 film for annual imaging dose assessment across kV radiography, fluoroscopy, and cone beam computed tomography (CBCT) imaging protocols, as...
Authors: Daniel A. Alexander, Anish Butala, Anthony Austin Kassaee, Neil Malhotra, Ian Messing, Gabrielle W Peters, Ryan M. Scheuermann
Affiliation: Department of Radiation Oncology and Applied Sciences, University of Pennsylvania
Abstract Preview: Purpose: Stereotactic Body Radiation Therapy (SBRT) for spinal metastases uses CBCT-based localization and highly conformal treatment delivery to increase the biologically equivalent dose to the targe...
Authors: Gary Y. Ge, Azmul Siddique, Jie Zhang
Affiliation: Department of Radiology, University of Kentucky, University of Kentucky
Abstract Preview: Purpose: Virtual grid technology addresses scattered radiation without a physical grid, offering the potential to reduce patient radiation dose while maintaining image quality. However, this potential...
Authors: Shahed Badiyan, Tsuicheng D. Chiu, Viktor M. Iakovenko, Steve Jiang, Christopher Kabat, Mu-Han Lin, Roberto Pellegrini, Arnold Pompos, Edoardo Salmeri, David Sher, Sruthi Sivabhaskar, Justin D. Visak
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, Global Clinical Science, Elekta AB, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Adaptive treatment planning requires robust strategies to enable streamlined on-couch processes, creating a significant barrier for planners transitioning from conventional to adaptive planni...
Authors: Hao-Wen Cheng, Jonathan G. Li, Chihray Liu, Wen-Chih Tseng, Guanghua Yan
Affiliation: University of Florida
Abstract Preview: Purpose: This study develops and evaluates deep learning (DL) models for predicting 3D dose distributions in simultaneous integrated boost (SIB) prostate cancer treatment using the Elekta Unity MR-Lin...
Authors: Nawal Alqethami, Felix Ginzinger, Prasannakumar Palaniappan, Marco Riboldi, Philipp Steininger, Wentao Xie
Affiliation: Research & Development, medPhoton GmbH, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich)
Abstract Preview: Purpose:
This study evaluates the image quality of Dual-Energy (DE) X-ray imaging for lung tumor tracking across various sizes and protocols, comparing its imaging dose to Single-Energy (SE) imagin...
Authors: Izabella L. Barreto, Aroon Pressram
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: Our clinical dual energy CT (DECT) head protocol reconstructs iodine-suppressed virtual non-contrast (VNC) images using the vendor-recommended slope for material discrimination. However, this...
Authors: Brianna Baek, David J. Carlson, Zhe (Jay) Chen, Dae Yup Han, Bon Tack Koo, Hyojun Park
Affiliation: Columbia University, Canyon Crest Academy, Department of Therapeutic Radiology, Yale University School of Medicine, Department of Radiation Oncology, Chung-Ang University Gwang Myeong Hospital
Abstract Preview: Purpose: To find an optimized treatment technique and shielding design for minimizing the dose to a fetus, a Monte-Carlo simulation was performed to evaluate the dosimetric contribution.
Methods: G...
Authors: Derek Matthew Garcia, Mallory Glenn, Stephen F. Kry, Ruitao Lin, Dennis S. Mackin, Tucker J. Netherton
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, University of Texas’ MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Houston
Abstract Preview: Purpose: This study aims to investigate the feasibility of implementing clinically relevant quality metrics for evaluating IROC SRS phantom plans, including conformity index (CI) and homogeneity index...
Authors: Zachary Carr, Katie W. Hulme, Zaiyang Long, Nathan A. Quails, Ashley Tao
Affiliation: Gundersen Health System, Ohio State University Wexner Medical Center, Mayo Clinic, Ohio State Wexner Medical Center, The Cleveland Clinic
Abstract Preview: Purpose: Meaningful interpretation of deviation index (DI) in clinical practice relies on appropriately set target exposure indices (EIT). EIT values for a given exam-view can be derived from the medi...
Authors: Hungcheng Hank Chen, Laura A. Doyle, Helena Frisbie-Firsching, Amy S. Harrison, Jackson D Reeves, Lindsay B Romak, Jon Strasser
Affiliation: Christiana Care
Abstract Preview: Purpose: Brass mesh bolus (BMB) is a high-density woven metal mesh which is an excellent alternative to tissue equivalent bolus in photon beams, offering improved surface conformality. Unlike utilizat...
Authors: Ehsan Abadi, Darrin Byrd, Paul E. Kinahan, Katie Marie Olivas, Ehsan Samei
Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, University of Washington
Abstract Preview: Purpose: To evaluate the impact of respiratory motion during CT acquisitions on PET image quantification using an integrated PET-CT simulation pipeline.
Methods: A validated CT simulator (DukeSim) ...
Authors: Yuemeng Feng, Hamid Sabet
Affiliation: Massachusetts General Hospital, Harvard Medical School
Abstract Preview: Purpose: We propose a novel brain-dedicated PET system comprising elliptical cylinder with a neck cut-out, supplemented by front and back panels to improve sensitivity and line-of-response sampling. T...
Authors: Hongyu Jiang, Wangyao Li, Dima Soultan, Fen Wang, Jun Xu
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: To validate the Auto-Beam Hold functionality via the MMI connection between Varian SGRT system IDENTIFY 3.0 and treatment linacs.
Methods: A treatment plan was created in the Eclipse TPS u...
Authors: Leigh A. Conroy, Thomas G Purdie, Christy Wong
Affiliation: Department of Medical Biophysics, University of Toronto, Princess Margaret Cancer Centre
Abstract Preview: Purpose: To develop a novel machine learning (ML) algorithm to evaluate and rank breast radiation therapy (RT) treatment plans based on treatment complexity for prioritization in multidisciplinary pee...
Authors: Beth Bradshaw Ghavidel, Benyamin Khajetash, Yang Lei, Meysam Tavakoli
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Emory University, Department of Radiation Oncology, Emory University
Abstract Preview: Purpose: Pancreatic cancer is among the most aggressive types of cancer, with a five-year survival rate of approximately 10%. Recent studies show that radiomics and deep learning (DL)-based methods ar...
Authors: Mehdi Amini, Minerva Becker, Simina Chiriac, Alexandre Cusin, Dimitrios Daskalou, Ghasem Hajianfar, Sophie Neveu, Marcella Pucci, Yazdan Salimi, Pascal Senn, Habib Zaidi
Affiliation: Geneva University Hospital, Division of Radiology, Diagnostic Department, Geneva University Hospitals, Service of Otorhinolaryngology-Head and Neck Surgery, Department of Clinical Neurosciences, Geneva University Hospitals
Abstract Preview: Purpose: Personalized prediction of vestibular schwannoma (VS) tumour growth is crucial for guiding patient management decisions toward observation versus intervention. This study proposes an automate...
Authors: Austin Castelo, Xinru Chen, Caroline Chung, Laurence Edward Court, Jaganathan A Parameshwaran, Zhan Xu, Jinzhong Yang, Yao Zhao
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose:
To develop a deep learning-based segmentation model to automatically delineate tumors from full-body PET/CT images.
Methods:
PET/CT image pairs of 91 patients were collected for this...
Authors: Katja M. Langen, William Andrew LePain, Robert Muiruri, Vivi Nguyen, Mosa Pasha, Roelf L. Slopsema, Alexander Stanforth, Yinan Wang, Mingyao Zhu
Affiliation: Emory Healthcare, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Intensity modulated proton therapy (IMPT) treatment planning for craniospinal irradiation (CSI) is complex and requires extensive effort from the planner. This study aims to enhance planning ...
Authors: David L. Barbee, David Byun, Matt Long, Jose R. Teruel Antolin, Michael J Zelefsky
Affiliation: NYU Langone Health
Abstract Preview: Purpose:
Online adaptive MR-Linac therapy requires contour adaptation, often adding 20 minutes to treatment time and reducing machine throughput. This study introduces a fully automated MR contour ...
Authors: Michael Joseph Dance, Shiva K. Das, John Dooley, David V. Fried, Spencer Lynch, Michael Repka, Shivani Sud, Neil Ari Wijetunga
Affiliation: University of North Carolina
Abstract Preview: Purpose: The growing complexity of radiation therapy treatment planning presents challenges in maintaining efficient clinical workflows while ensuring plan quality. This study evaluates the use of an ...
Authors: Maria Jose Almada, Bruno Forti, Patricia Murina, Carlos Daniel Venencia
Affiliation: Instituto Zunino - Fundacion Marie Curie, Dra.
Abstract Preview: Purpose: The use of VMAT for the breast requires duplication of the patient's CT, several planning structures, and patient-specific dose-volume constraints depending on the patient's anatomy, fraction...
Authors: Yankun Lang, Lei Ren, Dario B. Rodrigues
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose:
HTP of microwave (MW) phased-array systems determine MW antenna settings to maximize energy absorption (SAR in W/kg) in tumor. Conventional HTP algorithms calculate SAR based on electromag...
Authors: Majd Antaki, Rohini Bhatia, Gayoung Kim, Yosef Landman, Junghoon Lee, Akila N. Viswanathan
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Physics and Advanced Development Elekta
Abstract Preview: Purpose: Brachytherapy is a standard radiation therapy approach for cervical cancer, which directly delivers radiation source to the tumor using catheters. Treatment planning requires identification o...
Authors: Hajar Moradmand, Lei Ren
Affiliation: University of Maryland School of Medicine, University of Maryland
Abstract Preview: Purpose:
The Sharp-van der Heijde (SvH) score is essential for assessing joint damage in rheumatoid arthritis (RA) from radiographic images. However, manual scoring is time-intensive and prone to v...
Authors: Yifei Hao, Wenxuan Li, Xiang Li, Tao Peng, Yulu Wu, Fang-Fang Yin, Yue Yuan, Lei Zhang, Yaogong Zhang
Affiliation: Duke University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Diffusion-based deep-learning frameworks have been recently used in MRI resolution enhancement, or super-resolution. Multi-contrast MRI share common anatomical structures while holding comple...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski, Huanyi Zhou
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose: A new CT configuration utilizing a multiple X-ray-source array (MXA) is under development to mitigate cone-beam (CB) artifacts in single-rotation wide coverage imaging. We investigate the sam...
Authors: Steven Brown, Mike Hopkins, Jerimy C. Polf, Scott Sawyer, Benjamin L. Viglianti
Affiliation: H3D, inc, University of Michigan, M3D, Inc, M3D Imaging
Abstract Preview: Purpose: We characterized the sensitivity, energy dependence, and calibrated dose rate for a radiation imaging survey meter (RAVIN Cam; M3d inc., Ann Arbor MI) based on cadmium zinc telluride (CZT) cr...
Authors: Cristel Baiu, Laura Castaneda Martinez, Ivan M. Rosado-Mendez
Affiliation: University of Wisconsin, Department of Medical Physics, University of Wisconsin-Madison, Departments of Medical Physics and Radiology, University of Wisconsin-Madison
Abstract Preview: Purpose: 2D matrix array transducers (2DMAT) are advancing volumetric ultrasound due to their ability to provide more isotropic 3D resolution, fast volumetric imaging, and highly customizable focusing...
Authors: Julien Bancheri, Chau Giang Bui, Christopher M Lund, Morgan J Maher, Jamiel Nasser, Amy Parent, Monica Serban, Jan P. Seuntjens, Jason Z Yuan
Affiliation: University of Toronto, Medical Physics Unit, McGill University, Princess Margaret Cancer Centre, Princess Margaret Cancer Centre & University of Toronto
Abstract Preview: Purpose: Proton therapy (PT) has demonstrated greater precision and superior healthy tissue sparing compared to photon radiotherapy for various sites; however, PT systems are expensive, which limits g...
Authors: Wilfred R Furtado, Gary Y. Ge, Jie Zhang
Affiliation: Department of Radiology, University of Kentucky, University of Kentucky
Abstract Preview: Purpose: The United Kingdom and several other countries already have well-established diagnostic reference levels (DRLs) for gastrointestinal fluoroscopic procedures, whereas the United States does no...
Authors: Andrew Huang, Jonathan Huang, Andrew S Kennedy, Ellie Grace Kong, Ajay Zheng
Affiliation: New York Proton Center, Centennial Medical Center, Executive Medical Physics Associates, Sarah Cannon Cancer Institute, Belmont University
Abstract Preview: Purpose:
Lung stereotactic body radiotherapy (SBRT) is the standard of care for early-stage lung cancer. Respiratory phase gating can be applied to mitigate motion-induced effects. The purpose of t...
Authors: Casey E. Bojechko, Lance C Moore
Affiliation: University of California, San Diego, University of California San Diego
Abstract Preview: Purpose: EPID images collected during treatment can serve as an in-vivo error detection mechanism. Previous works have shown that comparing in-vivo EPID images to AI-predicted EPID images for IMRT pla...
Authors: Liyuan Chen, Steve Jiang, Chenyang Shen
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center
Abstract Preview: Purpose: Delays in radiation therapy (RT) initiation caused by conventional CT simulation processes can hinder timely treatment delivery and patient outcomes. This study proposes a Virtual Treatment S...
Authors: Amy Tien Yee Chang, Chi Wai Cheung, Tin Lok Chiu, Chen-Yu Huang, Chi Wa Kong, Pei-Xiong Li, Pak Hang Nam, Bin Yang, Siu Ki Yu
Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital
Abstract Preview: Purpose: This study introduces BrachyPlanCheck, an independent Monte Carlo (MC)-based dose calculation tool for 192Ir brachytherapy retrospective study or algorithm commissioning.
Methods: BrachyPl...
Authors: Humberto Monsivais, Brian A. Taylor, Francesco Versace
Affiliation: Purdue University, Department of Behavioral Science, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: To identify possible signatures of altered brain morphometry in nicotine-dependency via a structural covariance network approach.
Methods: Fifty-one healthy controls (HC:27M, mean age=...
Authors: Rachael Blair, Les Butler, Lillian Dickson, Kyungmin Ham, Charles Hartman, Kenneth (Kip) Matthews, Corinne Vanya
Affiliation: Louisiana State University, University of Minnesota, Refined Imaging LLC, Center for Advanced Microstructures and Devices
Abstract Preview: Purpose:
To develop and evaluate an x-ray interferometry system (XIS) for low-dose, high-sensitivity diagnostic imaging of lung diseases such as chronic obstructive pulmonary disease (COPD), asthma...
Authors: Martha J. Malin, Matthew Schelin
Affiliation: NYU Langone Health
Abstract Preview: Purpose: To evaluate the agreement between ExacTrac Dynamic (ETD) and CBCT-based positioning for spine SRS/SBRT treatments during initial patient setup and repositioning after intrafraction motion.
Authors: Rodrigo Delgadillo, Nesrin Dogan, Benjamin J. Rich, Stuart E Samuels, Levent Sensoy
Affiliation: University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Daily Cone beam CT (CBCT) images may be useful in detecting early morphological changes during head and neck cancer radiotherapy. The aim of this study was to evaluate the performance of CBCT...
Authors: Jean Bourbeau, Jim Hogg, Miranda Kirby, Meghan Koo, Kalysta Makimoto, Wan Tan
Affiliation: Montreal Chest Institute of the Royal Victoria Hospital, McGill University Health Centre, Toronto Metropolitan University, Centre for Heart Lung Innovation, University of British Columbia
Abstract Preview: Purpose: Chronic obstructive pulmonary disease (COPD) exacerbations are burdensome to patients and healthcare systems. CT imaging-derived measures of emphysema and airway remodeling have been shown to...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Iowa, Iowa Health Care
Abstract Preview: Purpose: In proton therapy, the substantial size of the gantry introduces sag, causing the proton isocenter to drift as a function of gantry angle. While the scanning magnets correct the beam’s isocen...
Authors: Ted Bartley, Steven Brown, Steven Chinn, Mike Hopkins, Stanley Leong, Jerimy C. Polf, Luke Rothermel, Scott Sawyer, Benjamin L. Viglianti
Affiliation: University of California School of Medicine, University of Michigan, H3D, inc, University Hospitals, M3D, Inc, M3D Imaging, California Pacific Medical Center
Abstract Preview: Purpose: In a collaboration between surgical oncologists and medical physicists, a new intra-operative gamma camera for imagining sentinel lymph nodes (SLN) during radio-guided SLN biopsy procedures h...
Authors: E Courtney Henry, Srinivas Cheenu Kappadath, Armeen Mahvash
Affiliation: UT MD Anderson Cancer Center
Abstract Preview: Purpose:
Characterization of hepatocellular carcinoma (HCC) tumor responses for single-arm single-center prospective 90Y-radioembolization clinical trial (n=40) that used patient-specific voxel-dos...
Authors: Serdar Charyyev, Kaan Dere, Edgar Gelover, Mohammad Khurram Khan, Liyong Lin, Mark McDonald, Cristina Oancea, Alexander Stanforth, Sibo Tian, Suk Whan (Paul) Yoon, Mingyao Zhu
Affiliation: Department of Radiation Oncology, Stanford University, Stanford University, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Advacam
Abstract Preview: Purpose: The conventional implementation of proton spatially fractionated radiotherapy (SFRT) utilizes physical collimators with apertures to generate minibeams, creating alternating regions of high-d...
Authors: Dominique Guillet, Arthur Lalonde, Bryan R. Muir, James Renaud, Karim Zerouali
Affiliation: Universite de Montreal, Centre Hospitalier de l'Universite de Montreal, National Research Council
Abstract Preview: Purpose:
To evaluate the dose rate dependence, beam quality dependence, and short-term stability of a novel flashDiamond (fD) prototype detector for conventional and ultra-high dose rate (UHDR) bea...
Authors: Brett G Erickson, Joseph P. Kowalski, Xinyi Li, Qiuwen Wu, Sua Yoo
Affiliation: Duke University, Mayo Clinic - Department of Radiation Oncology, Duke University Medical Center
Abstract Preview: Purpose: Characterization and commissioning of the BeO-based myOSLchip system was performed (per TG191) to assess its feasibility as a full replacement for the recalled Landauer aluminum oxide OSL in ...
Authors: Kainoa Calistro-Allen, Brendon J. Villegas
Affiliation: University of Alabama Birmingham
Abstract Preview: Purpose:
To compare differences in radiation output and image quality in clinical esophagrams across fluoroscope vendors in use at University of Alabama Birmingham, prompted by reports that a newly...
Authors: Amar K. Basavatia, Lee C. Goddard, Rachel Grimm, Wolfgang A. Tomé
Affiliation: Montefiore Medical Center
Abstract Preview: Purpose: To characterize the “MyOSL Chip” OSLD system for clinical use and compare the response of multiple readers to allow for utilization in a multi-clinic environment.
Methods: Dose calibration...
Authors: David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Blake Gaderlund, Ray Yang
Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: To address the root cause of dosimetric discrepancy for small central targets (<2cm) especially sensitive to geometric alignment of beamlets, by modeling higher-order oscillations of the coll...
Authors: Brian Burger, Carri K. Glide-Hurst, John W. Hayes, Carson Hoffman, Minglei Kang, Jessica R. Miller, Jordan M. Slagowski, Yuhao Yan
Affiliation: Department of Human Oncology, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Leo Cancer Care
Abstract Preview: Purpose: The combination of upright CT and patient positioner for particle therapy present tremendous potential for high precision IGRT and online adaptive radiation therapy (ART), where reliable CT p...
Authors: Kaile Li, Esmail Parsai
Affiliation: Alexander T. Augusta Military Medical Center, Alexander T. Augusta Miliary Medical Center
Abstract Preview: Purpose: To evaluate the sensitivity of the portal dosimetry system with the Arc CHECK system at identical Volumetric Modulated Arc Therapy (VMAT) setup
Methods: An Arc CHECK system from Sun Nuclea...
Authors: Petr Bruza, Jeremy Eric Hallett, Brian W Pogue, Yucheng Tang, Shiru Wang
Affiliation: NVIDIA Corp, Dartmouth College, Thayer School of Engineering, Dartmouth College, University of Wisconsin-Madison, University of Wisconsin - Madison
Abstract Preview: Purpose: Cherenkov imaging allows for real-time visualization of megavoltage X-ray or electron beam delivery during radiation therapy. By using a time-gated intensified CMOS camera synchronized with a...
Authors: Girish Bal, Thomas I. Banks, Bin Cai, Yesenia Gonzalez, Zohaib Iqbal, Paul M. Medin, Rameshwar Prasad, Chenyang Shen, Robert Timmerman, Yuanyuan Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: Each year more than one million pacemakers and 200k cardioverter-defibrillators are implanted in patients worldwide. The presence of a CIED introduces challenges to the delivery of radiation ...
Authors: Ergun E. Ahunbay, Colette Gage, Abdul Kareem Parchur, Eric S. Paulson
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: AI-generated synthetic CT (sCT) images address challenges with prior sCT approaches, including atlas- and threshold-based methods. Commercial AI-based sCT tools have been introduced. This wor...
Authors: James Benton, Andrew Dewar, Benjamin C Lee, Ryan Y Lee
Affiliation: Radiotherapy Clinics of Georgia, Urology of Greater Atlanta
Abstract Preview: Purpose:
The purpose of our investigation was to determine if pre-treatment factors could predict urinary morbidity after combination radiation treatment for localized prostate cancer.
Methods:<...
Authors: Colin Adam Doyle, Celeste Winters
Affiliation: Department of Diagnostic Radiology, Oregon Health & Science University, School of Medicine, Oregon Health & Science University
Abstract Preview: Purpose: To audit our radioactive iodine (I-131) dosimetry protocol, review dosimetry methods used at other facilities, investigate the clinical impact of I-131 dosimetry at our facility, and test the...
Authors: Kai-Cheng Chuang, Oana I. Craciunescu, Christopher Kelsey, Joseph Kowalski, Nicole Larrier, Xinyi Li, Sheridan G. Meltsner, Anna E. Rodrigues, Yang Sheng, Qiuwen Wu
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose: To clinically implement a Volumetric Modulated Arc Therapy (VMAT) procedure for Total Body Irradiation (TBI) with off-the-shelf tools.
Methods: Patient is treated on linac couch with a hyb...
Authors: Dylan Yamabe Breitkreutz, Lee Chin, Brige P. Chugh, Mark D'Souza, Brian M. Keller, Anthony Kim, Michelle K. Nielsen, Arjun Sahgal
Affiliation: Sunnybrook Health Sciences Centre
Abstract Preview: Purpose: The Elekta Unity MR-linac delivers highly conformal SBRT treatments using IMRT. These treatment plans require patient-specific quality assurance (PSQA) measurements to detect discrepancies be...
Authors: Madeleine Arbogast, David Dorndos, Denise E Foltz, Justin Fraser, Damodar Pokhrel, William St Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Department of Neurosurgery, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: For stereotactic radiosurgery (SRS) treatments of intracranial arteriovenous malformations (AVM) and fistulas (AVF), same-day Leksell Gamma Knife (GK) is the preferred modality. Long-term cli...
Authors: Haijian Chen, Katja M. Langen, William Andrew LePain, Claire Tran, Mingyao Zhu
Affiliation: Emory Healthcare, Emory University, Georgia Institute of Technology
Abstract Preview: Purpose: To validate the performance of a commercial deep-learning segmentation (DLS) tool for head and neck cancer (HNC) and thoracic and abdominal cancer (TAC) by comparing it to manual segmentation...
Authors: Xuelian Chen, John Ginn, Zhuhong Li, Kaizhong Shi, Chunhao Wang, Jianliang Wang, Chuan Wu, Zhenyu Yang, Fang-Fang Yin, Jingtong Zhao
Affiliation: The First People's Hospital of Kunshan, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, Department of Radiation Oncology, Duke Kunshan University
Abstract Preview: Purpose: Developing deep learning-based models for accurate automated breast cancer diagnosis from mammography presents significant challenges due to the small size and subtle nature of breast lesions...
Authors: Gulakhshan M Hamad, Sina Mossahebi, Yannick P. Poirier, Amit Sawant
Affiliation: University of Maryland School of Medicine, Maryland University Baltimore
Abstract Preview: Purpose:
The combination of ultra-high dose rate (UHDR) proton therapy, known for normal tissue sparing, with spatially-fractionated radiotherapy (SFRT), promising enhanced tumor control and tissue...
Authors: Xiaoda Cong, Rohan Deraniyagala, Xuanfeng Ding, Xiaoqiang Li, Jian Liang, Peilin Liu, Craig Stevens, Xiangkun Xu, Weili Zheng
Affiliation: Corewell Health William Beaumont University Hospital, Corewellhealth William Beaumont University Hospital, William Beaumont University Hospital, Corewellhealth William Beaumont Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital
Abstract Preview: Purpose:
Commission a step-and-shoot arc therapy(SPArc-step&shoot) for treating head-neck cancer patients as a desired interim milestone toward full dynamic treatment.
Methods:
An in-house de...
Authors: Carla D. Bradford, Linda Ding, Yansong Geng, Alan Hartford, I-Lin Kuo, Salvatore LaRosa, Joshua N Wancura
Affiliation: University of Massachusetts Chan Medical School
Abstract Preview: Purpose: When treating nasal skin cancers, electron beam radiotherapy dose distributions can be improved by using custom bolus to compensate for uneven surfaces. Here we describe our experience commis...
Authors: Maria F. Chan, Indra J. Das, Xiuxiu He, Seng Boh Gary Lim, Jeonghoon Park, Yunjie Yang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: There is a need for accurate and flexible in-vivo dosimetry systems, particularly for special procedures. Effective dosimetry is crucial for dose verification and maintaining records. A new r...
Authors: Rex Carden, Carlos E. Cardenas, Ho-hsin Rita Chang, John B Fiveash, Heinzman A. Katherine, Yogesh Kumar, Gaurav Nitin Rathi, Richard A. Popple, Kayla Lewis Steed
Affiliation: University of Alabama at Birmingham
Abstract Preview: Purpose: Brain metastases (BMs) often require multiple radiotherapy (RT) courses as new lesions appear. Comparing follow-up imaging with prior RT plans is time-intensive. We developed an AI tool that ...
Authors: Kimberly Chan, Anke Henning, Mahrshi Jani, Andrew Wright, Xinyu Zhang
Affiliation: Advanced Imaging Research Center (AIRC), UT Southwestern Medical Center
Abstract Preview: Purpose: To evaluate the performance of multiple deep learning architectures for MRSI reconstruction and determine their effectiveness in maintaining high-resolution metabolite mapping while reducing ...
Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Elsa Bifano Pimenta
Affiliation: University of São Paulo (USP), Institute of Physics
Abstract Preview: Purpose: This study evaluates the similarity between the linear attenuation coefficients of soft tissues and 3D printing materials in diagnostic imaging range using the Euclidean distance approach.
Authors: Theodore Higgins Arsenault, Beatriz Guevara, Rojano Kashani, Raymond F. Muzic, Gisele Castro Pereira, Alex T. Price
Affiliation: University Hospitals Seidman Cancer Center, Case Western Reserve University Department of Biomedical Engineering
Abstract Preview: Purpose: Accurate dose prediction in radiotherapy is essential for treatment planning. This study evaluates four nnUnet-based models using the OpenKBP head and neck dataset: a baseline model (Model 1)...
Authors: Srinivas Cheenu Kappadath, Brian Michael Kelley, Benjamin P. Lopez
Affiliation: UT MD Anderson Cancer Center
Abstract Preview: Purpose:
Imaging systems are subject to errors from finite spatial resolution and voxel size. This work demonstrates their effect on dose algorithm {Monte Carlo (MC), dose-volume kernel (DVK), and ...
Authors: David J. Carlson, Yiu-Hsin Chang, Zhe (Jay) Chen, Hyosung Cho, Dae Yup Han, MinYoung Lee, Weili Zhong
Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine, Yonsei University
Abstract Preview: Purpose:
To compare the intra-fractional motion tracking sensitivity of prostate fiducial markers using triggered imaging and calypso tracking for prostate cancer cases.
Methods:
This study w...
Authors: Meghan Lubner, Krista McClure, Aria M. Salyapongse, Timothy P. Szczykutowicz, Giuseppe Toia, Ming Yan, Zhye Yin, Meghan Yue
Affiliation: GE HealthCare, Departments of Radiology and Medical Physics, University Wisconsin-Madison, GE Healthcare, University of Wisconsin-Madison, UW-Madison, University of Wisconsin Madison, Department of Radiology
Abstract Preview: Purpose: To evaluate virtual unenhanced (VUE) and true unenhanced (TUE) human subject images on a prototype deep silicon photon-counting detector (PCD) CT with prototype algorithms.
Methods: 5 subj...
Authors: Matthew R. Hoerner, Maryam Naseri, Mena Shenouda
Affiliation: Yale University School of Medicine, Yale University
Abstract Preview: Purpose: To evaluate acquisition parameters of computed tomography (CT) scanner protocols across different machines to provide patients and clinicians consistent care and image quality, respectively.<...
Authors: Wesley A. Belcher, Aidan Burke, Matthew Green, Taylor Stamey
Affiliation: ECU Health, East Carolina University Brody School of Medicine
Abstract Preview: Purpose: The purpose of this study was to determine the effect of using deep inhalation breath hold (DIBH) vs. free breathing (FB) and intensity-modulated radiation therapy (IMRT) vs. 3D for right-sid...
Authors: Eric N Carver, Julia Marks
Affiliation: Brown University
Abstract Preview: Purpose: The clinical applicability of radiomic features is hindered by challenges in stability and reproducibility. To address this, researchers are establishing image and feature standardizations an...
Authors: Afrouz Ataei, Victor Moy, Mark P. Supanich
Affiliation: Rush University
Abstract Preview: Purpose: This study evaluates the impact of ultra-high resolution (UHR) mode on the visualization of small vessels in coronary computed tomography angiography (CTA) using a photon-counting CT scanner....
Authors: Yunfeng Cui, Will Giles, Xinyi Li, Ke Lu, Jennifer C. O'Daniel, Anna E. Rodrigues, Chunhao Wang, Lana Wang, Yibo Xie, Sua Yoo, Jingtong Zhao
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose:
To establish quantitative measurement of plan modulation for SRS/SBRT treated with Volumetric Modulated Arc Therapy (VMAT) on C-arm LINACs.
Methods:
A total of 461 plans were analyze...
Authors: Tianyuan Dai, Xiaoying Fan, Shuting Wang, Yong Yin
Affiliation: Department of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: The purpose of this study was to investigate the interplay effect during intra-fractional motion and the effect of the robust optimization parameters for inter-fractional motion in the intens...
Authors: Krystal M. Kirby, Aliasghar Rohani, Christopher W. Schneider, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center, Louisiana State University, Baton Rouge, Louisiana
Abstract Preview: Purpose: Accurate treatment delivery in MR-guided radiotherapy (MRgRT) systems requires consistent imaging quality assurance (QA) to assess MR image quality. However, standard QA phantoms have limited...
Authors: Tetsuo Fukuda, Hideaki Hirashima, Kohei Kawata, Yukako Kishigami, Takashi Mizowaki, Mitsuhiro Nakamura, Yohei Sawada, Maika Urago
Affiliation: Kyoto University, kyotoUnivercity, Hitachi high-tech, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University
Abstract Preview: Purpose: To present the comprehensive commissioning results of the O-ring shaped linac, OXRAY.
Materials and Methods: OXRAY enables a novel three-dimensional unicursal noncoplanar irradiation metho...
Authors: Laura I. Cervino, Karen Episcopia, Hsiang-Chi Kuo, Sangkyu Lee, Seng Boh Gary Lim, Shih-Chi Lin, Grace Tang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: This study evaluated the performance of the HyperSight Cone-Beam Computed Tomography (CBCT) system on a TrueBeam C-arm LINAC (TB) and two Ethos ring-gantry LINACs (ES) for adaptive radiation ...
Authors: Gourav Jhanwar, Mojtaba Tefagh, Masoud Zarepisheh
Affiliation: The University of Edinburgh, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
Radiotherapy treatment planning involves solving computationally-intensive and time-consuming optimization problems. Central to these problems is a large matrix known as the dose-influence...
Authors: Baher Elgohari, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Jeonghoon Park, Tyler Wilhite
Affiliation: UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, UPMC Hillman Cancer Center, UPMC, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
To compare toxicity between consecutive-daily (QD) with every-other-day (QoD) delivery of lung stereotactic-body-radiation (SBRT) for central non-small-cell lung cancer (NSCLC).
Methods...
Authors: Fangfen Dong, Jiaming Li, Xiaobo Li, Weipei Wang, Zhixin Wang, Bing Wu, Benhua Xu, Yong Yang, Yifa Zhao
Affiliation: Department of Radiation Oncology, Fujian Medical University Union Hospital/Fujian Key Laboratory of Intelligent Imaging and Precision Radiotherapy for Tumors/Clinical Research Center for Radiology and Radiotherapy of Fujian Province (Digestive, Hematologi, Zhangpu County Hospital, School of Medical Imaging, Fujian Medical University
Abstract Preview: Purpose: To explore the construction and clinical application value of a deep learning-based positioning error prediction model, providing a reference for optimizing iSCOUT system-guided precision rad...
Authors: Abdusalam Abdukerim
Affiliation: Institute for Medical Imaging Technology, Ruijin Hospital
Abstract Preview: Purpose:
Coronary computed tomography angiography (CCTA) is the gold-standard non-invasive test for coronary artery disease (CAD), but iodine contrast agents (ICA) pose limitations in specific popu...
Authors: Zhaoyang Fan, Eric Nguyen, Dan Ruan, Jiayu Xiao
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiology, University of Southern California, University of Southern California
Abstract Preview: Purpose: MR vessel wall imaging (VWI) has been shown to be effective for evaluating intracranial atherosclerosis disease. However, VWI typically also requires an MR angiography (MRA) in the same imagi...
Authors: Kota Hirose, Daisuke Kawahara, Jokichi Kawazoe, Yuji Murakami
Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University
Abstract Preview: Purpose: Synthesizing medical images can address the lack of or unscanned medical images, reducing scanner time and costs. However, paired image scarcity remains a challenge for image synthesis. We pr...
Authors: Min Cheol Han, Chae-Seon Hong, Changhwan Kim, Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, HO Lee, Kwangwoo Park, Ye-In Park, Junyoung Son
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Yongin Severance Hospital, Yonsei University College of Medicine
Abstract Preview: Purpose: Overresponse in surface in-vivo dosimetry using optically stimulated luminescence dosimeter (OSLD) depends on the beam incidence angle. This study aimed to investigate correction factors to d...
Authors: Angela Gathers, Christina Henson, Sakuntala Jagabattuni, Mark A. Newpower
Affiliation: University of Oklahoma HSC, Department of Otolaryngology, University of Oklahoma HSC, University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: A previous departmental study showed an increase in ototoxicity (hearing loss) rates in head & neck cancer (HNC) patients treated with Intensity Modulated Proton Therapy (IMPT) vs. x-ray radi...
Authors: Gregory A Azzam, Danielle Cerbon, Laura Huang, Panayiotis Mavroidis, Diana Molinares, Stuart E Samuels, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center, University of Miami Sylvester Comprehensive Cancer Center, Mount Vernan Rehabilitation Medicine Associates, Department of Radiation Oncology, University of Miami, University of North Carolina
Abstract Preview: Purpose: This study examines the correlation of different dose volume metrics of the skin, sternocleidomastoid (SCM) muscle and subcutaneous tissue (subcut) structures with the skin systemic sclerosis...
Authors: Abdullah A. Alshreef, Grant A. McAuley, Jerry D Slater
Affiliation: Loma Linda University Medical Center, Loma Linda University
Abstract Preview: Purpose: In this project we investigate the use of a single permanent magnet quadrupole to create pass-through proton minibeams suitable for potential clinical use and preclinical radiobiology experim...
Authors: Seung Yeon Kim, Grant A. McAuley, Ju A Park, Jerry D Slater
Affiliation: Loma Linda University
Abstract Preview: Purpose: The production of proton minibeams in standard PBS nozzles is challenging due to the effects of finite source beam divergence and multiple Coulomb scattering. Herein we investigate the use of...
Authors: Xu Chen, Jun Lian, Yunkui Pang, Pew-Thian Yap
Affiliation: University of North Carolina at Chapel Hill, Huaqiao University
Abstract Preview: Purpose: Unsupervised CBCT-to-CT translation in the pelvic region is essential for accurate radiotherapy delivery and adaptive image-guided interventions. However, current models for cross-modality tr...
Authors: Derek Tang, Susu Yan
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: To evaluate the performance of a multi-task automated-segmentation and synthetic CT generation model (sCT) and investigate its application in an adaptive proton therapy workflow.
Methods: ...
Authors: Mark Bowers, Gabriel Carrizo, Jimmy Caudell, Vladimir Feygelman, Kevin Greco, Christian Hahn, Jihye Koo, Kujtim Latifi, Fredrik Lofman, Jacopo Parvizi, Muqeem Qayyum, Caleb Sawyer
Affiliation: RaySearch Laboratories, Moffitt Cancer Center
Abstract Preview: Purpose: Head and neck (H&N) radiotherapy planning is complex, with multiple competing objectives. We endeavored to improve efficiency of planning by developing a deep learning (DL) model trained to p...
Authors: Gayoung Kim, Junghoon Lee
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University
Abstract Preview: Purpose: 3D time-of-flight magnetic resonance angiography (TOF-MRA) is widely used for visualizing cerebrovascular structures. Accurate segmentation of cerebrovascular structures is critical for relia...
Authors: Weikang Ai, Xiaoyu Hu, Xun Jia, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Department of Biomedical Engineering, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Real-time tumor tracking is critically important for respiratory motion management for lung cancer radiotherapy. A previously proposed application of a photon counting detector involves measu...
Authors: Beth Bradshaw Ghavidel, Chih-Wei Chang, Yuan Gao, Priyanka Kapoor, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Jill Remick, Justin R. Roper, Zhen Tian, Xiaofeng Yang
Affiliation: Whinship Cancer Institute, Emory University, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Current cone-beam computed tomography (CBCT) typically requires no less than 200 degrees of angular projections, which prolongs scanning time and increases radiation exposure. To address thes...
Authors: Gary Y. Ge, Abdullah-Al-Zubaer Imran, Kazi Ramisa Rifa, Charles Mike Weaver, Jie Zhang
Affiliation: University of Kentucky
Abstract Preview: Purpose: With renewed attention on CT radiation dose management following CMS approval of new dose measures, establishing image quality–based target doses for every protocol has become essential. Whil...
Authors: Mostafa Cham, Matthias K Gobbert, Zhuoran Jiang, Sina Mossahebi, Ruth Obe, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma
Affiliation: University of Maryland School of Medicine, UMBC, University of Maryland Baltimore County, University of Maryland, Baltimore County, Stanford University, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc, Department of Infomation Systems, UMBC
Abstract Preview: Purpose: Compton camera (CC)-based prompt gamma imaging (PGI) offers real-time proton range verification. However, its limited-angle measurements cause severe distortions in PGI, affecting its clinica...
Authors: Sang Hee Ahn, Nalee Kim, Do Hoon Lim
Affiliation: Samsung Medical Center, Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine
Abstract Preview: Purpose: MRI offers superior soft-tissue contrast, aiding tumor localization and segmentation in radiation therapy, which traditionally relies on oncologists' expertise. This study compares CNN-based ...
Authors: Xinyi Fu, Dan Ruan, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Digitally reconstructed radiographs (DRRs) are easy to generate and widely used to establish research protocols in pulmonary diagnosis and image-guided radiotherapy tasks. A question remai...
Authors: Anke Henning, Mahrshi Jani, Tianyu Wang, Andrew Wright, Xinyu Zhang
Affiliation: Advanced Imaging Research Center (AIRC), UT Southwestern Medical Center
Abstract Preview: Purpose: Proton MRSI offers critical metabolic insights into diseased brain processes but is prone to artifacts, and current post-processing methods are often insufficient, resulting in low-quality da...
Authors: Xiaoyu Duan, Xiang Li, Wenbo Wan, Lei Zhang, Yiwen Zhang
Affiliation: Duke University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Breast screening has been proved to reduce breast cancer mortality by early detection and treatment for patients. Mammography is the most common and widely used technique for breast cancer sc...
Authors: Mingli Chen, Huan Amanda Liu, Weiguo Lu, Lin Ma
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Mayo Clinic
Abstract Preview: Purpose: To reduce the back-and-forth in planning process between physicians and dosimetrists resulting from trade-off exploration, we proposed a novel deep learning framework called DeepTuning.
Me...
Authors: Maryellen L. Giger, Fahd Hatoum, Robert Tomek, Heather M. Whitney
Affiliation: The University of Chicago
Abstract Preview: Purpose: To assess the importance of applying stratified sampling across demographic attributes (including age, sex, race, and ethnicity) when constructing training and testing datasets for ML-based d...
Authors: Jacqueline M. Andreozzi, Tess Armstrong, Shiva Bhandari, John M Bryant, Jessica M Frakes, David J. Gladstone, Sarah E Hoffe, Kujtim Latifi, Arash Naghavi, Steven Nichols, Ibrahim M. Oraiqat, Russell Palm, Gage H. Redler, Stephen A Rosenberg, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Thayer School of Engineering, Dartmouth College, Department of Radiation Oncology, Ohio State University, Moffitt Cancer Center, Department of Radiation Oncology, Moffitt Cancer Center
Abstract Preview: Purpose: The MR-linac provides unique opportunities for integrating advanced imaging into radiotherapy workflows, but the lower sensitivity of systems like the 0.35T model can pose challenges for diff...
Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: To assess the dependency of CT numbers on position in the field-of-view (FOV) using single-energy (SE) and dual-energy (DE) images and energy-integrating detector (EID) and photon-counting de...
Authors: Alexander Baikalov, Luke Connell, Nicholas Coupey, Nolan M. Esplen, Rebecca Lim, Chinh Nguyen, Emil Schueler
Affiliation: Northwell, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: FLASH radiotherapy delivered using electron linear accelerators (LINAC) requires precise control and minimal variation of dose rate and We developed a robust external beam control system (EBC...
Authors: Edward A. Opalko, Matthew B. Podgorsak, Dheerendra Prasad
Affiliation: Roswell Park Comprehensive Cancer Center
Abstract Preview: Purpose: To design a 3D printed insert for Varian’s SRS Head Phantom that allows for multi-planar film dosimetry and to evaluate its ability in end-to-end testing for Gamma Knife treatments.
Method...
Authors: Zongsheng Hu, Yuting Li, Radhe Mohan, Emil Schueler, Uwe Titt
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: In previous work, we developed an irradiation system for pre-clinical ultra-high-dose-rate(FLASH) radiotherapy experiments based on synchrotron proton beamline. However, the beam current limi...
Authors: Peter Balter, Andres V Cibrian, Song Gao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: The purpose of this study is to demonstrate a means of detecting misaligned jaw face angles on the Varian TrueBeam based on a beam symmetry metric for electron beam profiles.
Methods: Duri...
Authors: Xinhui Duan, Roderick W. McColl, Mi-Ae Park, Liqiang Ren, Gary Xu, Kuan Zhang, Yue Zhang
Affiliation: UT Southwestern Medical Center, Department of Radiology, UT Southwestern Medical Center, Imaging Services, UT Southwestern Medical Center
Abstract Preview: Purpose:
Image-based deep-learning noise-reduction techniques have been developed for photon-counting CT (PCCT) to improve image quality with reduced radiation dose. The denoising strength is typic...
Authors: Clifford Ghee Ann Chua, Calvin Wei Yang Koh, Kah Seng Lew, Zubin Master, Sung Yong Park, Hong Qi Tan, Andrew Wibawa
Affiliation: National Cancer Centre Singapore
Abstract Preview: Purpose: To investigate the impact of spot position deviation on reference dosimetry measurements using different delivery patterns and to determine the optimal delivery pattern for reference dosimetr...
Authors: Ashley Elizabeth Bonner, Michael G. Snyder
Affiliation: Corewell Health William Beaumont University Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital
Abstract Preview: Purpose: Develop and evaluate metrics for assessing beam matching of profiles across Elekta linacs in a multisite clinical setting.
Methods: Four Elekta linear accelerators (three VersaHD and one A...
Authors: Chibawanye I. Ene, Sherise D. Ferguson, Ping Hou, Vinodh A. Kumar, Ho-Ling Anthony Liu, Kyle R. Noll, Sujit S. Prabhu, Jian Ming Teo, Max Wintermark
Affiliation: Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose:
Functional brain atlases are used to guide clinical functional MRI (fMRI) analyses. Imprecise assertions may introduce the ecological fallacy as atlases are reflective of the constituent c...
Authors: Morgan A. Daly, David J. Goodenough, Andrew M. Hernandez, John M. Hoffman, Joshua Levy, Michael F. McNitt-Gray, Ali Uneri, Bino Varghese
Affiliation: University of California, George Washington University, David Geffen School of Medicine at UCLA, Johns Hopkins Univ, University of Southern California, The Phantom Laboratory
Abstract Preview: Purpose: Quantitative imaging is affected by CT acquisition and reconstruction conditions, limiting robustness in multi-site or -scanner studies. This work aimed to develop a dataset that will enable ...
Authors: Chase Cochran, Damodar Pokhrel, William St Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Currently, intraocular disease is primarily treated via COMS-plaques brachytherapy. Various stereotactic approaches via photons/proton beam have also been implemented (CyberKnife/GammaKnife/p...
Authors: Jacob Gooslin, Ellis Lee Johnson, Damodar Pokhrel
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: HyperArc radiosurgery permits treatment of multiple brain lesions using a single-isocenter improving treatment planning efficiency and workflow. A key stereotactic planning aspect is an indep...
Authors: Ulrich Langner, Timothy Leech, Oleksii Semeniuk
Affiliation: Brown University Health
Abstract Preview: Purpose: To standardize and improve quality of the chart review process, while simultaneously increasing the efficiency of the physicist, by allowing them to allocate more time for other items.
Met...
Authors: Hyo-Min Cho, Cheolpyo Hong, Changwoo Lee, Sunyoung Lee
Affiliation: Daegu Catholic University, Korea Research Institute of Standards and Science (KRISS), Korea Research Institute of Standards and Science
Abstract Preview: Purpose: With the increasing prevalence of metabolic syndrome, the importance of diagnosing obesity and fatty liver diseases has grown significantly. As a result, there is a rising demand for non-inva...
Authors: Gregory T. Armstrong, James E. Bates, Kristy K. Brock, Laurence Edward Court, Matt Ehrhardt, Danielle Friedman, Aashish C. Gupta, Donald Hancock, Rebecca M. Howell, Cindy Im, Tera S Jones, Choonsik Lee, Wendy Leisenring, Taylor Meyers, Lindsay Morton, Chaya Moskowitz, Joe Neglia, Vikki Nolan, Caleb O'Connor, Kevin C. Oeffinger, Constance A. Owens, Arnold C. Paulino, Chelsea C. Pinnix, Sander Roberti, Cecile Ronckers, Susan A. Smith, Kumar Srivastava, Lucie Turcotte
Affiliation: Department of Medicine, Duke University School of Medicine, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, The University of Texas MD Anderson Cancer Center, Department of Oncology, St. Jude Children’s Research Hospital, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, Division of Pediatric Epidemiology and Clinical Research, University of Minnesota, Division of Childhood Cancer Epidemiology, University Medicine at Johannes Gutenberg University Mainz, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Pediatrics, University of Minnesota, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Biostatistics, St. Jude Children’s Research Hospital, Clinical Research Division, Fred Hutchinson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences
Abstract Preview: Purpose: To (1) develop and validate a novel anatomically realistic pediatric/adolescent population-based breast model, (2) incorporate model into an age-scalable female reference phantom, and (3) dem...
Authors: Pradeep Bhetwal, Yingxuan Chen, Wookjin Choi, Michael Dichmann, Adam Dicker, Rupesh Ghimire, Yevgeniy Vinogradskiy, Maria Werner-Wasik
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: Radiomics has emerged as a powerful tool in medical research. However, the lack of standardized and reproducible pipelines limits its clinical adoption. This study developed a robust and scal...
Authors: Tsuicheng D. Chiu, Weiguo Lu, Aaron Thomlinson, You Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose: To develop and validate an MR-compatible anthropomorphic motion phantom to assess liver motion, real-time dosimetry, and gating system performance under controlled and reproducible respirator...
Authors: Alejandro Bertolet, Isaac Meyer, Harald Paganetti, Jan PO Schuemann, Wook-Geun Shin
Affiliation: Massachusetts General Hospital, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: To develop a methodology for Monte Carlo modeling of cell-specific DNA geometries based on Hi-C data using TOPAS-nBio, and to evaluate early DNA damage distributions.
Methods: Hi-C data of...
Authors: Adedamola Adeniyi, Bryan Bednarz, Malick Bio Idrissou, Reinier Hernandez, Ohyun Kwon, Brian W. Miller, Zachary S Morris, Maya Takashima, Jamey Weichert
Affiliation: Departments of Radiation Oncology and Medical Imaging, University of Arizona, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin–Madison, Department of Radiology, School of Medicine and Public Health, University of Wisconsin–Madison, Department of Human Oncology, School of Medicine and Public Health, University of Wisconsin–Madison
Abstract Preview: Purpose: As radiopharmaceutical therapy (RPT) becomes more prevalent in clinical applications, understanding dose-response relationships in the tumor microenvironment (TME) and normal tissues is essen...
Authors: Hyo-Min Cho, Changwoo Lee
Affiliation: Korea Research Institute of Standards and Science
Abstract Preview: Purpose: We develop sphere phantoms to assess spatial resolution of computed tomography (CT) systems and validate its usability using table-top X-ray experiment systems.
Methods: We manufactured sp...
Authors: Nadège Anizan, David Broggio, Eric Chojnacki, Estelle Davesne, Didier Franck, Stéphanie Lamart, Alexandre Pignard
Affiliation: Institut Bergonié, Service de Physique Médicale, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSN-RES/SEMIA/LSMA
Abstract Preview: Purpose: To develop an innovative method enabling a comprehensive uncertainty budget associated to personalized absorbed doses for 177Lu-PSMA therapy and providing probability distributions of all dos...
Authors: Kaile Li
Affiliation: Alexander T. Augusta Miliary Medical Center
Abstract Preview: Purpose: To develop a experimental method in observation of beam profile transfer model in intensity modulated radiotherapy (IMRT).
Methods: A picket fence plan was generated in Eclipse treatment p...
Authors: John M. Boone, Andrew M. Hernandez, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski
Affiliation: Johns Hopkins University, University of California, UT MD Anderson Cancer Center, University of New Mexico Albuquerque, UC Davis Health
Abstract Preview: Purpose: To significantly improve image quality relative to clinically deployed digital breast tomosynthesis (DBT) systems, which use a 1D acquisition geometry (an arc), with a 2D image acquisition ge...
Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, James Tam, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
The aim of the study is to develop a trade-off prediction model to efficiently guide the treatment planning process for patients with stage III non-small cell lung cancer (NSCLC).
Metho...
Authors: Adam P. Berdusco, Matthew R. Ceelen, Renata Farrell, Carri K. Glide-Hurst, Will Martin, Charles F. Maysack-Landry, Morgan A. McGauley, James Rice, Jordan M. Slagowski, Yuhao Yan
Affiliation: Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Upright radiotherapy (RT) is now available although this novel vertical CT and positioner presents unique challenges for quality assurance and testing methodologies. We have designed and buil...
Authors: Jared Baggett, Wesley E. Bolch, Lukas M. Carter, Laura Dinwiddie, Benjamin Taylor Heggie, Adam Leon Kesner, Juan Camilo Ocampo Ramos, Graham Joseph Stoddard
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, University of Florida, MD Anderson
Abstract Preview: Purpose: The objective of this study is to develop a physical phantom to quantify tube current modulation (TCM) and assess the limitations of a TCM model used in Monte Carlo patient CT organ dose esti...
Authors: John Kildea, Odette Rios-Ibacache, Amal Zouaq
Affiliation: McGill University, Polytechnique Montréal
Abstract Preview: Purpose:
Even though Electronic medical records (EHRs) are now in widespread use in healthcare, and Artificial Intelligence tools incorporating radiomics are used to identify tumors in medical imag...
Authors: Jung Han Nam, Wonmo Sung
Affiliation: Department of Biomedical Engineering and Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Department of Biomedical Engineering and Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Korea
Abstract Preview: Purpose: This study aims to develop a whole-body blood flow framework based on the ICRP 145 standard vascular phantom to simulate the spatiotemporal trajectories of blood cells in the human vasculatur...
Authors: Luke Connell, Nolan M. Esplen, Elise Konradsson, Albert C. Koong, Ziyi Li, Steven Hsesheng Lin, Kevin Liu, Billy W Loo, Devarati Mitra, Radhe Mohan, Emil Schueler, Takeshi Takaoka, Uwe Titt, Xiaochun Wang, Ming Yang
Affiliation: The University of Texas MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: This study aimed to assess radiation-induced gastrointestinal (GI) toxicity in mice subjected to abdominal irradiation using protons at ultra-high-dose-rate (UHDR) and conventional dose-rates...
Authors: Michael Lamontagne, Ileana Pazos, Jerimy C. Polf, Joseph W. Robertson, Teniola Tobun, Ronald E. Tosh, Michael Zwolak
Affiliation: Biophysics and Biomedical Research Group, Microsystems and Nanotechnology Division, National Institute of Standards and Technology, M3D, Inc, National Institute of Standards and Technology, Dosimetry Group, Radiation Physics Division, National Institute of Standards and Technology
Abstract Preview: Purpose: To study how damage to DNA molecules increases and changes as a function of the type and dose of radiation.
Methods: DNA molecules of a known length (number of base pairs (BP)) within ...
Authors: Gregory T. Armstrong, James E. Bates, Christine V. Chung, Lei Dong, Ralph Ermoian, Jie Fu, Christine Hill-Kayser, Rebecca M. Howell, Meena S. Khan, Sharareh Koufigar, John T. Lucas, Thomas E. Merchant, Taylor Meyers, Tucker J. Netherton, Constance A. Owens, Arnold C. Paulino, Sogand Sadeghi
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, St. Jude Children's Research Hospital, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, St. Jude Children’s Research Hospital, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, University of Washington/ Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences
Abstract Preview: Purpose: Clinical workflows often rely on auto-segmentation tools trained on adult data, which may exhibit suboptimal performance in pediatric imaging due to inherent anatomical variations and smaller...
Authors: Ehsan Abadi, Njood Alsaihati, Steven T. Bache, Mridul Bhattarai, Cindy Marie McCabe, Francesco Ria, Ehsan Samei
Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Duke University Health System, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: To compare and contrast alternative methods including reader (in hominum), phantom (in phantasma), in vivo, and in silico methods deployed to assess the performance of photon counting (PCCT) ...
Authors: Robert Fucetola, Jiayi Huang, Zhihua Liu, Chongliang Luo, Tong Zhu
Affiliation: Washington University School of Medicine, Washington University in St. Louis, School of Medicine
Abstract Preview: Purpose:
This prospective observational study investigates radiation-induced white matter (WM) injuries using longitudinal diffusion tensor imaging (DTI) in patients with diffuse glioma following r...
Authors: Fatemeh Akbari, Artemis Dalby, Nelson A. Miksys, Prarthana Pasricha, Rowan M. Thomson
Affiliation: Ackerman Cancer Center, Carleton University
Abstract Preview: Purpose: To investigate dose evaluations for GammaTile brachytherapy, a novel treatment for brain malignancies. The analysis focuses on the impact of tissue heterogeneities, including the presence of ...
Authors: Ana Laura Burin, Maysa Müller Ferreira Gesserame, David Alexander Urbina Leal, Ilca Marli Moitinho Amaral Medeiros, Silas Leonel Pereira Miranda, Thuany Corrêa Nogueira, Maria da Penha Alburquerque Potiens, Pedro Henrique Ricardo, Maria Eduarda Zaganin Rigo, Orlando Rodrigues, Priscila Santos Rodrigues, Wilmmer Alexander Arcos Rosero, Maria Elisa Chuery Martins Rostelato, Sabrina Spigaroli Sgrignoli, Ana Catarina Koka de Souza Silva, Cristhian Ferreira Talacimon, Paulo Victor dos Santos Tavares, Lara El Hajj Teodoro, Carlos Alberto Zeituni, José Neres de Almeida
Affiliation: IPEN - USP
Abstract Preview: Purpose: Perform three-dimensional dosimetry of radioactive gold nanoparticles (¹⁹⁸AuNPs) using Fricke xylenol gel (FXG), aiming to determine the dose distribution and evaluate the method's effectiven...
Authors: Motohiro Kawashima, Adrian Kugara, Masao Nakao, Shuichi Ozawa, Mutsumi Tashiro, Maria Varnava
Affiliation: Gunma University Heavy Ion Medical Center, Hiroshima High-Precision Radiotherapy Cancer Center
Abstract Preview: Purpose: This study aimed to evaluate the time-dependent dose rate characteristics of a scanning carbon ion beam using a fast-response plastic scintillator detector (PSD), with a focus on its potentia...
Authors: Xiance Jin
Affiliation: 1st Affiliated Hospital of Wenzhou Medical University
Abstract Preview: Purpose:
Deep learning deformable registration models was proposed to predict optimal dose distributions a with a few of optimal planned doses using a few-shot learning for cervical cancer.
Meth...
Authors: Tianyuan Dai, Xiaoying Fan, Shuting Wang, Yong Yin
Affiliation: Department of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: Decreased lymphocytes increase the risk of infections and other problems. Radiation exposure can cause the development of severe lymphopenia. In this study, we used a dynamic blood flow model...
Authors: Yi Li
Affiliation: Department of Radiation Oncology, the First Affiliated Hospital of Xi'an Jiaotong University
Abstract Preview: Purpose: Advances in radiotherapy technology are crucial for improving cervical cancer (CC) treatment. This study explores a novel X-ray and γ-ray dual-modality radiation (TaiChiB) system, comparing i...
Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...
Authors: Adebayo Abe, Samuel Olaolu Adeneye, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Sylvester Entonu, Muhammad Habeebu, Adedayo O. Joseph, Oluwaseyi Oderinde, Oluwadara Ojediran, Margaret Dideolu Taiwo
Affiliation: University of Ibadan, University of Lagos, Missouri University of Science and Technology, Purdue University, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre
Abstract Preview: Purpose:
Spatially Fractionated Radiation Therapy (SFRT) is an advanced radiotherapy technique designed to deliver highly heterogeneous radiation doses, aiming to optimize tumor control while minim...
Authors: Jordan B Lunsford, Sagar Pokhrel, Ashkan Shafiee, Curtis S. Whiddon
Affiliation: Atrium Health Wake Forest Baptist, University of North Carolina, Atrium Health Wake Forest Baptist High Point Medical Center
Abstract Preview: Purpose: To investigate the dosimetric characteristics of a platinum cured silicone rubber material (Platsil) for use as custom bolus in radiotherapy
Methods: Sheets of 2, 4, 6, and 8 mm Platsil we...
Authors: Wesley S. Culberson, Ryan Gardner, Patrick M Hill, Mark Pankuch, Karsten K. Wake
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Wisconsin, Northwestern Medicine Proton Center
Abstract Preview: Purpose: To assess the dosimetric capabilities of Sun Nuclear (Melbourne, FL) EDGE Diode Detectors™ for measurements in the plateau region of pencil beam scanning (PBS) fields. Many clinical dosimeter...
Authors: Ahmad Amoush, Adam C. Riegel
Affiliation: Columbia University Irving Medical Center
Abstract Preview: Purpose: To investigate the dosimetric differences between the reference CT plan, the scheduled plan, and the adaptive plan for a bladder cancer patient treated with Varian Ethos system.
Methods: A...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: Prostate stereotactic body radiation therapy (SBRT) requires precise dose delivery to the target volume and organ-at-risk (OAR) sparing. This study compares MR-Linac (MRL) and CyberKnife (CK)...
Authors: Kin Yin Cheung, Chen-Yu Huang, Chi Wah Kong, Ka Ki Lau, Pei-Xiong Li, Pak Hang Nam, Mei Yan Tse, Jierong Wang, Bin Yang, Siu Ki Yu, Jing Yuan, Chi To Yung, Shang Peng Felix Yung
Affiliation: Medical Physics Department, Hong Kong Sanatorium and Hospital, Research Department, Hong Kong Sanatorium and Hospital
Abstract Preview: Purpose: Intrafraction motion management remains a major challenge in magnetic resonance-guided radiotherapy (MRgRT). The recent clinical release of an active motion management system aims to enhance ...
Authors: Enzo Charles Aucca, Roger Challco, Andres M. Gonzales Galvez, Carmen SANDRA Guzman Calcina, Jimmy Hernandez-Bello, Modesto Montoya, Renzo Aaron Ocampo, Erick Paniagua, Miguel Alberto Risco-Castillo, Dante E. Roa, Renzo E. Romero, William Souza Santos, Mirko Salomón Alva Sánchez
Affiliation: Graduate Program in Information Technologies and Health Management, University of Porto AlegreFederal University of Health Sciences of Porto Alegre, Universidad Tecnologica del Peru, Pontificia Universidad Catolica del Peru, Electronic Engineering Department, Leonard Cancer Institute - Radiation Oncology, Universidad Nacional de Ingenieria, Universidad Nacional de Ingenieria, Electronic Engineering Department, Federal University of Sergipe, HRS Oncology International, Universidad Nacional Federico Villareal
Abstract Preview: Purpose: Provide Monte Carlo (MC) and experimental dosimetric assessments of a 3D cubic electronic detector array based on percent depth doses (PDDs), profiles, linearity, and dose rate response of ph...
Authors: Kathryn J. Dess, Martha M. Matuszak, Dan Polan
Affiliation: University of Michigan
Abstract Preview: Purpose: A recent survey demonstrated 18 of 20 top academic institutions have implemented auto-segmentation. Studies to date have focused on geometric contour changes and dosimetric differences using ...
Authors: Lining Chen, Zhitao Dai, Shumei Jia, Yajun Jia, Enzhuo Quan
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital， Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: This work reviewed 12 patient clinical LRT treatments in physics view including geometric and dosimetric parameters and discussed the pros and cons related to the latter.
Methods: Geometri...
Authors: J Isabelle Choi, Meng Wei Ho, Isabel Lin, Hang Qi, Qi Zeng, Ajay Zheng
Affiliation: New York Proton Center, Scarsdale High School
Abstract Preview: Purpose: Proton therapy is a promising treatment modality for breast cancer due to its unique dosimetric advantage. Accurate dose calculation is critical to ensure effective treatment outcomes. The fo...
Authors: Xiaoyi Dai, Manju Liu, Weiwei Sang, Pulin Sun, Fan Xia, Zhenyu Yang, Fang-Fang Yin, Chulong Zhang, Rihui Zhang
Affiliation: Jiahui International Hospital, Radiation Oncology, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose:
Current deep learning-based sparse-view CBCT reconstruction methods are prone to hallucinatory artifacts, as they rely on inferred image details that may not correspond to true anatomical ...
Authors: Daniel H. Bushe, Arthur Lalonde, Hoyeon Lee, Harald Paganetti, Brian Winey
Affiliation: Universite de Montreal, Massachusetts General Hospital, Massachusetts General Hospital and Harvard Medical School, University of Hong Kong
Abstract Preview: Purpose: Improving the precision and fidelity of daily volumetric imaging is essential for enabling adaptive proton therapy (APT). While cone-beam CT (CBCT) provides daily volumetric imaging, their ut...
Authors: Kenneth W. Gregg, Beatriz Guevara, Lauren E Henke, Rojano Kashani, Kyle O'Carroll, Gisele Castro Pereira, Christian Erik Petersen, Alex T. Price, Meiying Xing, Reine abou Zeidane
Affiliation: university hospital, University Hospitals Seidman Cancer Center
Abstract Preview: Purpose:
Experimental data have shown the inconsistent monitor unit and target coverage in Ethos 1.1. This can lead to inaccurate dose delivery, compromising patient safety and treatment outcomes. ...
Authors: Dennis A. Cheek, Wei Luo, Cameron Thayer-Freeman, Brien Timothy Washington
Affiliation: UT Southwestern Medical Center, University of Kentucky, Department of Radiation Medicine, University of Kentucky
Abstract Preview: Purpose: To investigate the effect of variation in the α/β of cervical cancer on clinical outcome for cervix cancer patients treated with radiation therapy.
Methods: A distribution of experimentall...
Authors: Thomas R. Mazur, Kevin Renick, Matthew C. Schmidt, Xiaodong Neo Zhao
Affiliation: Washington University in St. Louis School of Medicine, Washington University School of Medicine
Abstract Preview: Purpose: To compare dose calculation accuracy for single-isocenter multi-target stereotactic radiosurgery plans (SIMT-SRS) in Eclipse V18.0 with enhanced leaf model (ELM) using the anisotropic analyti...
Authors: Sean P. Boyer, Shae Gans, Mingcheng Gao, Draik B. Hecksel, Mark Pankuch
Affiliation: Northwestern Medicine Proton Center, Northwestern Medicine Chicago Proton Center
Abstract Preview: Purpose: Protons deposit a large portion of their energy at the end of their range in a region known as the Bragg peak, which may increase the relative biological effective (RBE) dose in this region. ...
Authors: Chieh-Ya Chiu, Shen-Hao Li, Hsin-Hon Lin, Shu-Wei Wu
Affiliation: Department of Medical Imaging and Radiological Sciences, Chang Gung University, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital Linkou
Abstract Preview: Purpose: Monte Carlo simulation enables precise calculation of dose distribution in proton therapy through tracing the radiation particles with patient tissues. However, achieving clinical-level preci...
Authors: Nan Li, Yaoying Liu, Shouping Xu, Gaolong Zhang
Affiliation: Department of Radiation Oncology, School of Physics, Beihang University, School of physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: In intensity-modulated proton therapy (IMPT) for head and neck cancer, CBCT registration ensures accurate setup, minimizing dose errors. Unlike IMRT, IMPT plans directly define tumor volumes ...
Authors: Rita Buono, Elisabetta Cagni, Roberta Castriconi, Surendra Bahadur Chand, Marco Esposito, Claudio Fiorino, Valeria Landoni, Aldo Mazzilli, Eugenia Moretti, Lorenzo Placidi, Giulia Rambaldi Guidasci, Alessia Tudda
Affiliation: IRCCS San Raffaele Scientific Institute, Department of Advanced Technology, IRCCS Regina Elena National Cancer Institute, ASU FC Medical Physics, University Hospital of Parma AOUP, ICTP, B.P. Koirala Memorial Cancer Hospital, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Fatebenefratelli Isola Tiberina – Gemelli Isola
Abstract Preview: Purpose: To explore the feasibility and educational impact of transferring knowledge-based planning (KBP) models—developed using Italian breast radiotherapy data—to a Nepalese hospital, thereby demons...
Authors: John Ford, Yu Fujiwara, Isao Murata, Zavier Ndum Ndum
Affiliation: Osaka University, Texas A&M University
Abstract Preview: Purpose: This study investigates how particle energy affects radiation quality and biological effectiveness with the inclusion of medical implants. Our research group used microdosimetric analysis to ...
Authors: Lei Ren, Jie Zhang
Affiliation: University of Maryland School of Medicine
Abstract Preview: Purpose: 4D-CBCT is valuable for imaging anatomy affected by respiratory motions to guide radiotherapy delivery. However, 4D-CBCT often has undersampled projections acquired in each respiratory phase ...
Authors: Yang Lei, Tian Liu, Ren-Dih Sheu, Meysam Tavakoli, Jing Wang, Kaida Yang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Emory University
Abstract Preview: Purpose:
The study aimed to improve target and organ at risk (OAR) segmentation in low-dose-rate brachytherapy (LDR-BT) for prostate cancer treatment, by integrating clinical guidelines into deep l...
Authors: Ameer Elaimy, Theodore Lawrence, Charles S. Mayo, Seyyedeh Azar Oliaei Motlagh, Benjamin S. Rosen
Affiliation: University of Michigan
Abstract Preview: Purpose: To analyze the impact of clinical features on short-term survival, toxicity, and poor outcomes in HCC patients treated with SBRT,using automated data aggregation and enhanced algorithms with ...
Authors: Michael Butkus, Camilo M. Correa Alfonso, Olga M. Dona Lemus, James Arthur Perez-Sanchez
Affiliation: University of Miami
Abstract Preview: Purpose: Accurate skin dose calculation is essential for treating superficial lesions such as those of the breast, chest wall, and scalp. Clinical treatment planning systems often rely on approximatio...
Authors: Minbin Chen, Ke Lu, Kaizhong Shi, Chunhao Wang, Chuan Wu, Zhenyu Yang, Fang-Fang Yin, Jingtong Zhao
Affiliation: The First People's Hospital of Kunshan, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, Department of Radiation Oncology, Duke Kunshan University
Abstract Preview: Purpose: MRI-based automatic detection of brain metastases is often challenged by the small size and subtle nature of metastases. This study aimed to develop a novel deep learning-based brain metastas...
Authors: Lakshmi Ananthakrishnan, Xinhui Duan, Liqiang Ren, Gary Xu, Kuan Zhang, Yue Zhang
Affiliation: Department of Radiology, UT Southwestern Medical Center, Imaging Services, UT Southwestern Medical Center
Abstract Preview: Purpose: Daily quality control (QC) programs for diagnostic CT include water CT number (HU), standard deviation (SD), and visual artifact evaluations. At our institution, 70 keV virtual monoenergetic ...
Authors: David Chighvinadze, Chieh-Wen Liu, Sugandima Weragoda, Ping Xia
Affiliation: Cleveland Clinic Sandusky, Cleveland Clinic
Abstract Preview: Purpose: To explore the feasibility of using coplanar beams with collimator angle optimization for brain SRS plans with Halcyon system.
Methods: This study used a dataset of 26 patients with 2-3 br...
Authors: Chin-Cheng Chen, Chingyun Cheng, Longfei Diao, Benjamin Durkee, Minglei Kang, Haibo Lin, LeLe Liu, Yangguang Ma, Xuanqin Mou, YunTong Pei, Charles B. Simone, YuFei Wang, Xueqing Yan, Xingyi Zhao, Wang Zhengda
Affiliation: Peking University, St. Jude Children's Research Hospital, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, School of Software Engineering, Xi’an Jiaotong University, School of information and communications engineering, Faculty of electronic and information engineering, Xi’an Jiaotong University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: This study evaluates the effectiveness of apertures in improving lateral dose falloff in proton pencil beam scanning (PBS) single-energy Bragg peak (SEBP) FLASH radiotherapy (RT). The approac...
Authors: Felicia Chu, Qiongge Li, Jian Liu
Affiliation: Inova Hospital, Brown University Rhode Island Hospital, Hofstra University Medical Physics Program
Abstract Preview: Purpose:
This study aims to enhance the efficiency of stereotactic body radiation therapy (SBRT) planning for lung cancer by developing and evaluating optimization templates derived from historical...
Authors: Paul B. Ravindran
Affiliation: Christian Institute of Health Sciences and Research
Abstract Preview: Purpose: In the past decades, Master's programs in Medical Physics in India have made significant strides, though many have faced challenges in accessing adequate resources for didactic lectures and p...
Authors: Yang Lei, Haibo Lin, Tian Liu, Charles B. Simone, Shouyi Wei, Ajay Zheng
Affiliation: Icahn School of Medicine at Mount Sinai, New York Proton Center
Abstract Preview: Purpose: Radiation-induced lung injury (RILI), encompassing pneumonitis and fibrosis, represents a critical dose-limiting factor in lung cancer radiation therapy. Variability in treatment outcomes is ...
Authors: Rashmi Bhaskara, Oluwaseyi Oderinde
Affiliation: Purdue University
Abstract Preview: Purpose: This study proposes a novel approach to overcoming CBCT image quality limitations by developing an improved synthetic CT (sCT) generation method based on a CycleGAN architecture using Vision ...
Authors: Nan Li, Yaoying Liu, Shouping Xu, Xinlei Xu, Gaolong Zhang
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, School of physics, Beihang University, Beihang University, Department of Radiation Oncology
Abstract Preview: Purpose:
CT simulation is essential for radiation therapy preparation but has limitations in distinguishing lesions. Contrast-enhanced CT (CECT) improves lesion detection and characterization, but ...
Authors: Angel Gomez, Titania Juang, Grace Gwe-Ya Kim, Boyu Meng
Affiliation: UC San Diego, UCSD, University of California San Diego
Abstract Preview: Purpose: Single-Isocenter Multiple Targets (SIMT) Stereotactic Radiosurgery (SRS) is widely used for its precision and effectiveness. However, standardized quality assurance (QA) protocols for SIMT SR...
Authors: Ruth Afanador, Daniela Branco, John M Bryant, John Campbell, Clement Chaphuka, Samuel A. Einstein, David B. Flint, Jeffrey R. Kemp, Mussa Kumwembe, Daniel J Mollura, Joseph Weygand
Affiliation: RAD-AID International, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, UNC Health, Malawi National Cancer Center, Kamuzu Central Hospital, Penn State College of Medicine, Sutter Health, New York University, University of California San Diego / California Protons, Department of Radiation Oncology, Moffitt Cancer Center
Abstract Preview: Purpose: Malawi, a landlocked country in southeastern Africa with a population of over 20 million, ranks among the world’s least-developed nations and has the fourth-lowest gross domestic product per ...
Authors: Muhammad Ramish Ashraf, Girish Bal, Daniel Pham, Murat Surucu
Affiliation: RefleXion Medical, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University
Abstract Preview: Purpose: To determine minimum target size and FDG contrast thresholds for reliable Biology-guided Radiation Therapy (BgRT) delivery using a systematic phantom study.
Methods: A custom 3D-printed ph...
Authors: Kevin M Brom, Jaydev K. Dave, Chunming Gu, Nicholas J. Hangiandreou, Zaiyang Long, Donald J Tradup
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Ultrasound scanner onboard quality checks for shear wave elastography (SWE) rely on operator judgement and are insufficient. This study aims to establish a protocol for quality assessment and...
Authors: Gregory T. Armstrong, James E. Bates, Lei Dong, Ralph Ermoian, Jie Fu, Christine Hill-Kayser, Rebecca M. Howell, Sharareh Koufigar, John T. Lucas, Thomas E. Merchant, Tucker J. Netherton, Sogand Sadeghi
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, St. Jude Children's Research Hospital, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, St. Jude Children’s Research Hospital, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, University of Washington/ Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: This study evaluates the adaptability and limitations of commercially available (MIM, RayStation) tools trained on predominately adult datasets (ages 20–60+ years) for delineating organs at r...
Authors: Ramin Abolfath, Alejandro Bertolet, Kofi M. Deh, Rao Khan, Vanessa Sanders, Daniel Suarez-Garcia
Affiliation: Massachusetts General Hospital and Harvard Medical School, University of Sevilla, Brookhaven National Laboratory, Howard University
Abstract Preview: Purpose: To compare the efficacy of 225Ac to 90Y for local cancer therapy by quantifying DNA damage using Monte Carlo simulations.
Methods: The TOPAS n-Bio toolkit was used to simulate the irradiat...
Authors: Christopher G. Ainsley, Pradeep Bhetwal, Yingxuan Chen, Wookjin Choi, Vimal K. Desai, Karen E. Mooney, Adam Mueller, Hamidreza Nourzadeh, Yevgeniy Vinogradskiy, Maria Werner-Wasik
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: MR-guided adaptive radiotherapy (MRgART) has demonstrated improved outcomes for patients with pancreatic cancer. However, the time-consuming re-segmentation of targets and organs-at-risk (OAR...
Authors: Emily Helen Hayes, Chihray Liu
Affiliation: University of Florida
Abstract Preview: Purpose: To evaluate dosimetric discrepancies in bladder dose calculations among rigid, deformed, and manual contouring methods in prostate cancer patients and assess dose variations resulting from bl...
Authors: Nema Bassiri, Kristen A. Duke, Neil A. Kirby, Thomas Wilson Klender, Christien Kluwe, Niko Papanikolaou, Holly Paschal, Karl H. Rasmussen, Daniel L. Saenz, Michelle de Oliveira
Affiliation: Miami Cancer Institute, University of Texas HSC San Antonio, UT Health San Antonio
Abstract Preview: Purpose: Determine the practical usability for three phantoms to be used with the ExacTrac Dynamic thermal imaging system. Thermal-guided imaging can be used for inter and intra motion management, pat...
Authors: Theodore Higgins Arsenault, Kyle O'Carroll, Christian Erik Petersen, Alex T. Price, Meiying Xing
Affiliation: University Hospitals Seidman Cancer Center
Abstract Preview: Purpose: To assess the performance of various supervised learning models’ ability to predict binary classification of radiomic data for head and neck (H&N) cancer treatment outcomes.
Methods: Using...
Authors: Jacob S. Buatti, Kristen A. Duke, Malena Fassnacht, Neil A. Kirby, Parker New, Niko Papanikolaou, Arkajyoti Roy, Yuqing Xia, Michelle de Oliveira
Affiliation: The University of Texas San Antonio, UT Southwestern Medical Center, UT Health San Antonio
Abstract Preview: Purpose:
Quantifying and visualizing uncertainty is critical for building clinical trust in AI-generated dose distributions. This study evaluates Monte Carlo Dropout (MCD), Snapshot Ensemble (SE), ...
Authors: Ben Archibald-Heeren, Grace Gwe-Ya Kim, Kelly Kisling, Xenia Ray
Affiliation: UC San Diego, Icon Cancer Centres, University of California, San Diego, University of California San Diego
Abstract Preview: Purpose: To evaluate improvements in external beam plans for gynecological cancers from a novel planning solution: RapidArc Dynamic (RAD) (Varian Medical Systems, Palo Alto, CA) which optimizes VMAT w...
Authors: Yi-Fang Wang, Yading Yuan
Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology, Columbia University Irving Medical Center
Abstract Preview: Purpose: HyperSight, the latest CBCT technology from Varian Medical Systems, integrates rapid 6-second data acquisition with advanced iterative reconstruction and upgraded hardware. Previous studies h...
Authors: Jack Biondo, Audrey Magness, Anthony E. Mascia, Zhiyan Xiao, Yongbin Zhang
Affiliation: Cincinnati Children's Proton Therapy Center
Abstract Preview: Purpose: Proton FLASH-RT has shown promise reducing normal tissue toxicity while maintaining tumor control. However, in vivo experiments critically depend on achieving ultra-high dose rate (UHDR) and ...
Authors: Neha Devi, Deon M. Dick
Affiliation: Jaeger Corporation
Abstract Preview: Purpose: To evaluate the impact of bladder volume variation on small bowel dose in prostate cancer patients with nodal involvement and assess the efficacy of a 'half-full bladder' guideline for minimi...
Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Umesh Rana, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: DynamicARC is a novel pencil beam scanning (PBS) proton therapy technique with the potential to provide more conformal dose distributions and reduce treatment time. This study investigates th...
Authors: Shatha Al Afifi, Hana Baroudi, Leonard Che Fru, Laurence Edward Court, Suzanne B. Evans, Kent A. Gifford, Adam D. Melancon, Melissa P. Mitchell, Issa Mohamad, Patricia Murina, Manickam Muruganandham, Tucker J. Netherton, Callistus M. Nguyen, Joshua S. Niedzielski, Deborah L. Schofield, Simona Shaitelman, Willie Shaw, Sanjay S. Shete, Adam Shulman, Brendon Smith, Sheeba Thengumpallil, Carlos Daniel Venencia, Conny Vrieling
Affiliation: University of Cape Town, MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, University of the Free State, UT MD Anderson Cancer Center, King Hussein Cancer Center, Instituto Zunino - Fundacion Marie Curie, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Dra., Hirslanden Clinique des Grangettes, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Therapeutic Radiology, Yale University School of Medicine, Yale University, The University of Texas, MD Anderson, Houston TX
Abstract Preview: Purpose:
Automated contouring and planning tools are usually trained on single-institution datasets, seldom tested across diverse patient populations. This introduces a risk of population bias, res...
Authors: Andrew M Baschnagel, Jonathan W. Engle, Jessica E. Griffin, Gihan Gunaratne, Reinier Hernandez, Randall J Kimple, Aaron M. LeBeau, Natalie Y. Luo, Rachel Minne, Caroline M. Mork, Kwangok P Nickel, Jayden West, Madalynn R. Wopat
Affiliation: University of Wisconsin, University of Wisconsin, Department of Pathology and Laboratory Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin–Madison, University of Wisconsin - Department of Human Oncology, UW Madison, University of Wisconsin, Department of Medical Physics
Abstract Preview: Purpose: The Mesenchymal-Epithelial Transition gene (MET), a targetable cell surface receptor responsible for stimulating cell growth and proliferation, is altered in approximately 10% of non-small ce...
Authors: Mervat A. Alharbi, Wesley S. Culberson
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Medical Physics Department, School of medicine and Public Health, University of Wisconsin-Madison
Abstract Preview: Purpose: The charge collection using ionization chambers is challenging at ultra-high dose rates (UHDR) due to the high ion recombination The Exradin A30 prototype parallel-plate ion chamber manufactu...
Authors: Petr Bruza, David J. Gladstone, Lesley A Jarvis, Natasha Mulenga, Kevin J. Willy
Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center
Abstract Preview: Purpose: The goal of this work was to use Cherenkov emission imaging to verify patient position, accessory block positioning and dose delivery in Total Skin Electron Therapy (TSET).
Methods: A ...
Authors: Yuchao Hu, Yajun Jia, Zhangmin Li, Yong Sang, Jianan Wu, Man Zhao
Affiliation: Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, Guangzhou Concord Cancer Hospital, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital， Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: To evaluate the imaging dose of 4D-CBCT in patients treated with thoracic radiotherapy.
Methods: A model of the Elekta XVI imaging system was created in TOPAS software. Percentage depth do...
Authors: Stella Flampouri, Edgar Gelover, William Andrew LePain, Roelf L. Slopsema, Alexander Stanforth, Mingyao Zhu
Affiliation: Emory Healthcare, Emory University
Abstract Preview: Purpose: Little consideration was given to the change in dose rate (DR) observed when moving to pencil beam scanning (PBS). This study reports on DR in clinical prostate PBS plans. While dose distribu...
Authors: Ergun E. Ahunbay, Abdul Kareem Parchur, Eric S. Paulson, Ilaria Rinaldi, Angelo Schiavi, Li Zhao
Affiliation: Sapienza University of Rome, Department of Radiation Oncology (Maastro), GROW School for Oncology, Maastricht University Medical Centre+, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Secondary dose calculations (SDC) facilitate patient-specific quality assurance for online adaptive intensity-modulated proton therapy (IMPT). However, there is currently a lack of commercial...
Authors: Nobukazu Fuwa, Masato Horita, Takahiro Kato, Ryo Tanokura, Yuki Tominaga
Affiliation: Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Central Japan International Medical Center, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University
Abstract Preview: Purpose:
We have installed a new type of scanned proton therapy system (Varian ProBeam 360°TM). This study aimed to evaluate the four different dose calculation algorithms.
Methods:
Sixteen b...
Authors: Pat Esposito, Ashley Klein, Carmine Verna, Ling Zhuang
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: To evaluate dosimetric parameters and treatment delivery efficiency between volumetric modulated arc therapy (VMAT) and hybrid dynamic conformal arc (HDCA) on SRS and SBRT planning through st...
Authors: Fan Liu, Adam C. Riegel, Yi-Fang Wang
Affiliation: Columbia University Irving Medical Center
Abstract Preview: Purpose: HyperSight, Varian Medical Systems' latest CBCT technology, integrates rapid 6-second data acquisition with advanced iterative reconstruction, enabling precise real-time contouring and dose c...
Authors: Yu-Ying Lin, Yu Chen Shen
Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou
Abstract Preview: Purpose: This study evaluates the protective efficiency of lead glasses against radiation exposure to the eyes during angiography using optically stimulated luminescence dosimeters (OSLDs).
Methods...
Authors: Xinhui Duan, Vivek Nair, Liqiang Ren, KyuHo Song, Vasantha Vasan, Kuan Zhang, Yue Zhang
Affiliation: Department of Radiology, UT Southwestern Medical Center
Abstract Preview: Purpose: Minimizing radiation dose is crucial in CT colonography (CTC) screening and diagnosis. Tin (Sn) prefiltration is readily incorporated into clinical photon-counting CT (PCCT) scanners, yet its...
Authors: Ana Laura Burin, Ilca Marli Moitinho Amaral Medeiros, Priscila Santos Rodrigues, Maria Elisa Chuery Martins Rostelato, Sabrina Spigaroli Sgrignoli, Ana Catarina Koka de Souza Silva, Carla Daruich Souza, Cristhian Ferreira Talacimon, Lara El Hajj Teodoro, Carlos Alberto Zeituni
Affiliation: IPEN - USP, IPEN - Instituto de Pesquisas Energéticas e Nucleares
Abstract Preview: Purpose: The uniform distribution of phosphorus-32 (32P) in beta sources is essential to ensure the accuracy of radiotherapy treatments, such as those for paravertebral cancer. This study evaluated th...
Authors: Cem Altunbas, Farhang Bayat, Roy Bliley, Brian Kavanagh, Uttam Pyakurel, Tyler Robin, Ryan Sabounchi
Affiliation: Department of Radiation Oncology, University of Colorado School of Medicine, Taussig Cancer Center, Cleveland Clinic
Abstract Preview: Purpose: The use of image features extracted from serial CBCT images to assess radiotherapy response and toxicity is an active research area. However, poor image quality often compromises reliability ...
Authors: Thomas I. Banks, Bin Cai, Andrew R. Godley, Yang Kyun Park, Hao Peng, Rameshwar Prasad, Chenyang Shen, Shunyu Yan, Haozhao Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose:
The RefleXion® X1 (RefleXion Medical, Inc., Hayward, CA) uniquely integrates KVCT and PET as on-board image guidance for radiotherapy. It has been installed and commissioned for clinical u...
Authors: Chloe DiTusa, Panayiotis Mavroidis, Christopher W. Schneider, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center, University of North Carolina
Abstract Preview: Purpose: To evaluate and compare dose calculation differences between Monaco and AdaptBox by TheraPanacea on AI-generated pseudo-CTs (pCTs) from a CBCT.
Methods: Dose calculations in water phan...
Authors: Sabrina Campelo, Sandun Y. Jayarathna, Adam D. Melancon, Paige L. Nitsch, Christopher Ryan Peeler, Julianne M. Pollard-Larkin, Ramaswamy Sadagopan, Xiaochun Wang, George Zhao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Development of an in-house analytical simulation for streamlining photon counting detector (PCD) system protocols through measuring transmitted photon energy spectra through a Hafnium (Hf)-lo...
Authors: Michelle Alonso-Basanta, Joshua Bryer, Lei Dong, Barbara Garcia, Elissa Khoudary, Brandon M. Koger, Taoran Li, Michael Salerno, Karen Tang, Boon-Keng Kevin Teo
Affiliation: University of Pennsylvania
Abstract Preview: Purpose: The Varian HyperSight imaging solution features a workflow for planning on CBCT images (CBCTp). This study evaluates the feasibility of CBCTp images in the setting of an offline adaptive plan...
Authors: Arjit K. Baghwala, Devin J. Olek, Parth K. Patel, Ramiro Pino, Adam Yanez
Affiliation: Houston Methodist Hospital, Kaiser Permanente
Abstract Preview: Purpose: The Halcyon beam model in Eclipse is immutable and only includes output factors (OF) for fields down to 1x1 cm2. The TPS must extrapolate OFs for smaller fields used in stereotactic (SRS/SBRT...
Authors: Julie Colnot, Eric Deutsch, Christelle Huet, Danahé LeBlanc, Pauline Maury, Charlotte Robert, Imane Saïd Mansour, Cathyanne Schott, Francois Therriault-Proulx
Affiliation: INSERM U1030, Gustave Roussy, University Paris-Saclay, LDRI, IRSN, Medscint, THERYQ / INSERM U1030, Gustave Roussy, University Paris-Saclay, Université Paris-Saclay, Gustave Roussy, Inserm U1030, Radiothérapie Moléculaire et Innovation Thérapeutique
Abstract Preview: Purpose: FLASH radiotherapy, using ultra-high dose rates (UHDR, >100 Gy/s), spares healthy tissues while maintaining tumor control compared to conventional radiotherapy (CONV). However, UHDR dosimetry...
Authors: Muhammad Ramish Ashraf, Girish Bal, Daniel Pham, Murat Surucu
Affiliation: RefleXion Medical, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University
Abstract Preview: Purpose: To systematically evaluate the relationship between Activity Concentration (AC) obtained from the RefleXion PET-Linac with the maximum standardized uptake value (SUVmax) derived from a diagno...
Authors: Evan Barber, Gloria P. Beyer, Callum Hartley, Jordi Saez, Philip Wheeler
Affiliation: Department of Radiation Oncology, Hospital Clinic de Barcelona, Department of Radiotherapy Physics, Velindre University NHS Trust, Medical Physics Services, LLC
Abstract Preview: Purpose: To evaluate the Enhanced Leaf Model (ELM) in Eclipse v18 to the standard leaf model for the Halcyon multileaf collimator (MLC) using a measurement-based method.
Methods: The Halcyon’s doub...
Authors: Milad BaradaranGhahfarokhi, Ashley Elizabeth Bonner, James R. Burns, Annie Cooney, George X. Ding, Kenneth L. Homann, Guozhen Luo
Affiliation: Corewell Health William Beaumont University Hospital, Vanderbilt University Medical Center
Abstract Preview: Purpose: The goal of this study was to evaluate the performance of a new plastic scintillating detector (PSD) system with 0.5×0.5 mm2 and 1.0×1.0 mm2 probes (referred to as Medscint0.5 and Medscint1.0...
Authors: Chunhui Han, An Liu, William T. Watkins, Qiuyun Xu
Affiliation: Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the RefleXion X1 imaging system as a standalone positron emission tomography and computed tomography (PET/CT) simulator for radiotherapy treatment planning and adaptive re-plannin...
Authors: Oi-Wai Chau, Beata Gontova Bernat, Mary Gronberg, Yao Hao, Amanda M. Jackson, Nupur Karmaker, Dishane Chand Luximon, Osama R. Mawlawi, Ikechi Samuel Ozoemelam, Deepak Shrestha, William Swanson, Md Tofiz Uddin, Joseph Weygand, Afua A. Yorke
Affiliation: University of Michigan, Mayo Clinic, Champion Cancer Center, UT MD Anderson Cancer Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, University of Washington, Washington University in St Louis, Washington University School of Medicine, Department of Radiation Oncology, University of California, Los Angeles, National Institute of Cancer Research and Hospital, Emory University, Dept. of Medical Physics and Biomedical Engineering, Gono Bishwabidyalay, The University of Texas Southwestern Medical Center
Abstract Preview: Purpose: To evaluate perception and awareness of global medical physics (GMP) as a career path among medical physics professionals and trainees, identify opportunities to enhance professional developm...
Authors: Caiden Atienza, Pim T. S. Borman, Martin F. Fast, Daniel E. Hyer, Bas W. Raaymakers, Jeffrey E. Snyder, Prescilla Uijtewaal, Peter Woodhead
Affiliation: Department of Radiotherapy, University Medical Center Utrecht, Yale New Haven Health, University of Iowa
Abstract Preview: Purpose:
On conventional C-arm linacs, VMAT is the preferred delivery modality due to its superior efficiency and highly conformal dose distributions. MR-linacs offer superior soft-tissue imaging t...
Authors: Alejandro Bertolet, Jose Antonio Lopez-Valverde, Victor V. Onecha, Daniel Puerta
Affiliation: Dana Farber Cancer Institute/Brigham and Women's Hospital, Departamento de Física Atómica, Molecular y Nuclear, Universidad de Granada, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: Besides its superior dose conformity, proton therapy induces greater damage to tissue than conventional radiotherapies. This increased damage is usually quantified through the concept of rela...
Authors: Samuel L. Brady, Joseph G. Meier, Elanchezhian Somasundaram, Andrew T Trout
Affiliation: Cincinnati Children's Hospital Medical Ctr, Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose:
To analyze eye-tracker gaze data for insights into radiologists’ areas of focus in an observer study of whole-body PET images.
Methods:
For a comparative study of dose matched PET im...
Authors: Bing-Hao Chiang, Eric C. Ford, Juergen Meyer, Timothy D. Solberg
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: This study evaluated the potential risk reduction of various pretreatment patient-specific quality assurance (PSQA) programs for Intensity Modulated Radiation Therapy (IMRT) in mitigating fai...
Authors: Louis Archambault, Nicolas Drouin, Alexis Horik, Simon Thibault
Affiliation: Département de Physique, de Génie Physique et D'optique, et Centre de Recherche sur le Cancer, Université Laval, Département de Physique, de Génie Physique et D'optique, et Centre d'optique, photonique et laser, Université Laval
Abstract Preview: Purpose: To develop a novel type of real-time 3D dosimeter for the quality assurance of linear accelerators used in external beam radiotherapy.
Methods: An experimental setup was constructed using ...
Authors: Claus Belka, Stefanie Corradini, George Dedes, Nikolaos Delopoulos, Christopher Kurz, Guillaume Landry, Ahmad Neishabouri, Domagoj Radonic, Adrian Thummerer, Niklas Wahl, Fan Xiao
Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, LMU Munich, Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), National Center for Radiation Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO)
Abstract Preview: Purpose: In MR-guided online adaptive radiotherapy, MRI lacks tissue attenuation information necessary for accurate dose calculations. Instead of using deep learning methods to generate synthetic CT i...
Authors: Wen C. Hsi, Kayla Schneider
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Measurement-based patient-specific quality-assurance (PSQA) conducted with a 2D dosimeter to verify delivered dose of each field over 3 measurement-depths is time-consuming with limited se...
Authors: Jochen Cammin, Shifeng Chen, Arun Gopal, Kai Huang, Jason K Molitoris, Amit Sawant, Kai Wang
Affiliation: University of Maryland, Department of Radiation Oncology, University of Maryland School of Medicine, Maryland University Baltimore, Department of Radiation Oncology, University of Maryland Medical Center
Abstract Preview: Purpose: The HyperSight CBCT optional feature on Varian TrueBeam linacs offers a larger field-of-view, improved Hounsfield units (HU) accuracy, and overall improved image quality, including metal arti...
Authors: Melissa Bronson, Elizabeth L. Covington, Robert T. Dess, Joseph R. Evans, William C. Jackson, Charles S. Mayo, Michelle L. Mierzwa, Benjamin S. Rosen, VG Vinod Vydiswaran, Grant Weyburne, Zheng Zhang, Henry Zocher
Affiliation: PCORnet®, The National Patient-Centered Clinical Research Network, University of Michigan
Abstract Preview: Purpose: Diagnosis and staging are an integral part of cancer care, but this information is often scattered across various electronic medical records. The fragmentation increases overall documentation...
Authors: Noriko Kishi, Takashi Mizowaki, Mitsuhiro Nakamura, Yukine Shimizu
Affiliation: Kyoto University, Kyoto Univercity, Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University
Abstract Preview: Purpose: To predict tumor positions in markerless dynamic tumor tracking (ML-DTT)-VMAT by compensating for the asynchrony between the tumor and the diaphragm.
Methods: Rotational fluoroscopic X-ray...
Authors: Christine V. Chung, Laurence Edward Court, Meena S. Khan, Ethan B. Ludmir, Rachael M. Martin Paulpeter, Saurabh Shashikumar Nair, Callistus M. Nguyen, Joshua S. Niedzielski, Luis Augusto Perles
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Spatially Fractionated Radiation Therapy (SFRT) has re-emerged as an efficacious treatment approach for bulky solid tumors. RapidArc Dynamic (RAD) has unique beam delivery capabilities that m...
Authors: Sung Hwan Ahn, Yongha Gi, Jinju Heo, Jinyoung Hong, Yunhui Jo, Yousun KO, Hyeongjin Lim, Sang Yoon PARK, Myonggeun Yoon
Affiliation: Institute of Global Health Technology (IGHT), Korea University, Republic of Korea, Korea University, Samsung Medical Center
Abstract Preview: Purpose:
This study aims to evaluate the feasibility of real-time monitoring of conductivity changes induced by thermal variations during tumor treating fields (TTFields) therapy using Electrical I...
Authors: Sofia Beer, Menal Bhandari, Alec Block, Nader Darwish, Joseph Dingillo, Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Rajkumar Kettimuthu, Jason Patrick Luce, Ha Nguyen, John C. Roeske, George K. Thiruvathukal, Austin Yunker
Affiliation: Data Science and Learning Division, Argonne National Laboratory, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago, Department of Computer Science, Loyola University of Chicago
Abstract Preview: Purpose: Artificial intelligence (AI) generated synthetic medical images are seeing increased use in radiology and radiation oncology. Physician observer studies are an ideal way to evaluate the usabi...
Authors: Tae Kyu Lee
Affiliation: Allina Health
Abstract Preview: Purpose: To assess the feasibility of a dynamic-platform integrated with high-resolution patient-specific-quality-assurance (PSQ device for periodic quality assurance (PQA) and PSQA in respiratory-gat...
Authors: Jacob S. Buatti, Mu-Han Lin, Dominic Moon, David D.M. Parsons, David Sher, Justin D. Visak, Hui Ju Wang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Most current adaptive treatment planning systems (TPS) natively utilize static planning goals from the reference plan for online adaptive re-optimization. In complex head-and-neck cancer (HNC...
Authors: Xiaodong Wu, Xingchen Zhai, Weizhao Zhao
Affiliation: University of Miami
Abstract Preview: Purpose: The ZAP-X is a self-contained, self-shielded radiosurgery system utilizing a 3MV LINAC. Its self-shielded design, poses challenges for conventional beam quality assurance (QA) methods. This s...
Authors: Xinyuan Chen, Geoffrey D. Hugo, Alex T. Price, Pamela Samson, Tianyu Zhao
Affiliation: University Hospitals Seidman Cancer Center, University of South Florida, Washington University School of Medicine, WashU Medicine
Abstract Preview: Purpose: This study evaluates the financial viability of on-table simulation (CBCTp) enabled Halcyon system in radiation therapy. By leveraging Time-Driven Activity-Based Costing (TDABC), the analysis...
Authors: Xinyuan Chen
Affiliation: Washington University School of Medicine
Abstract Preview: Purpose: This study evaluates the financial viability of on-table simulation (CBCTp) enabled Halcyon system in radiation therapy. By leveraging Time-Driven Activity-Based Costing (TDABC), the analysis...
Authors: Resat Aydin, Joseph Barbiere, Brett Lewis, Roland Teboh
Affiliation: HUMC, Hackensack University Medical Center
Abstract Preview: Purpose:
Accurately compensating for respiratory-induced tumor motion is critical in BgRT, where precise delineation of volumes ensures effective dose delivery. We propose an integrated approach th...
Authors: Robert Berry, John Buatti, Nathan Burger, Ryan T. Flynn, Greg Johns, Maksim Kravchenko, Sergey Kutsaev, Yen-Po Lee, Marcos Ruelas, Joel J. St-Aubin, Timothy J. Waldron
Affiliation: RadiaBeam Technologies, University of Iowa
Abstract Preview: Purpose: To report the factory acceptance tests of a preclinical linear accelerator, the FLEX-9 electron FLASH linac from RadiaBeam Technologies.
Methods: The FLEX-9 FLASH electron linac is designe...
Authors: Girish Bal, David J. Carlson, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Henry S. Park
Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: This study explores the feasibility, accuracy, and dosimetric performance of hybrid biology-guided radiotherapy (BgRT) combined with image-guided radiotherapy (IGRT) for delivering sequential...
Authors: Niels Bassler, Jonathan Bortfeldt, Davide Boscaini, Francesco Evangelista, Guyue Hu, Ze Huang, Margarita Kozak, Julie Lascaud, Giulio Lovatti, Eero Lönnqvist, Jasper Nijkamp, Munetaka Nitta, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Babak Sharifi, Brita Singers Sørensen, Peter Thirolf
Affiliation: Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Ludwig-Maximilians Universität, Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital
Abstract Preview: Purpose: To perform the first in vivo application of a novel small animal radiation research platform combining on-board image-guidance with multi-field intensity modulated spot scanning delivery [1] ...
Authors: Barry Andricks, Stratton Black, Scott R. Floyd, Ashutosh Kotwal, Eric L. Martin, Stepan Mikhailov, Mark Oldham, Niccolo Terrando, Andrew Thompson, Ying Wu
Affiliation: Department of Physics, Duke University, Medical Physics Graduate Program, Duke University, Duke University, Department of Radiation Oncology, Duke University Medical Center, Triangle Universities Nuclear Laboratory
Abstract Preview: Purpose: To evaluate and quantify the effects of high energy electron radiation delivered at FLASH and conventional dose rates on the reproductive capability of adult C. elegans nematodes.
Methods:...
Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: This study introduces a novel template-guided deep learning framework for primary gross tumor volume (GTVp) segmentation, addressing challenges posed by diverse tumor types and enabling a uni...
Authors: Makunda Aryal, Qiongge Li, Sook Kien Ng, Christopher F. Njeh, Edwin Quashie, Senthamizhchelvan Srinivasan, Yun Wang
Affiliation: Indiana University Medical School, Memorial Health Care System, Indiana University, Inova Hospital, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: Linear-Quadratic-Linear (LQL) model is a modification of the traditional Linear-Quadratic model used in radiobiology to describe cell survival in response to radiation. The LQL model extends ...
Authors: Xianjin Dai, PhD, Michael Gensheimer, Praveenbalaji Rajendran, Lei Xing, Yong Yang
Affiliation: Department of Radiation Oncology, Stanford University, Massachusetts General Hospital, Harvard Medical School
Abstract Preview: Purpose: Recent advances in the automatic delineation of radiotherapy treatment targets, which incorporate linguistic clinical data extracted by large language models (LLMs) into traditional visual-on...
Authors: Chloe Min Seo Choi, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Cardiac substructure irradiation predisposes patients for poor outcomes in thoracic radiation therapy. A deep learning model was developed to segment the cardiac substructures invariant to co...
Authors: Kwang-Ho Cheong, Seungryong Cho, Joonil Hwang, Jae Won Jung, Hoyeon Lee, Raymond Hyunwoo Moon, Inhwan Yeo, Jihyung Yoon
Affiliation: East Carolina University, INOVA Schar Cancer Institute, University of Hong Kong, Hanllym University, KAIST, University of Rochester
Abstract Preview: Purpose: Monitoring a target and neighboring organs during beam delivery is crucial for successful radiotherapy (RT). Conventional transit imaging methods lack volumetric reconstruction capabilities, ...
Authors: Michelle Alonso-Basanta, Carl Denis, Wenbo Gu, Xinmin Liu, Ahmad Sakaamini, Rodney D. Wiersma
Affiliation: UCLA, University of Pennsylvania, CDR Systems
Abstract Preview: Purpose: Stereotactic radiosurgery (SRS) is a non-invasive technique used to treat functional abnormalities and small brain tumors. Traditional SRS relies on a rigidly fixed metal head ring, causing d...
Authors: Claire Keun Sun Park, Atchar Sudhyadhom, Veena Venkatachalam, Noah Warner
Affiliation: Harvard–MIT Program in Health Sciences and Technology, Massachusetts Institute of Technology, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: Modern radiotherapy achieves sub-millimeter spatial accuracy but fails to account for patient- and spatially-specific variations in biological response. Free radical generation (FRG), particu...
Authors: Uriel Aura, Qing Chen, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Meng Wei Ho, Sheng Huang, Minglei Kang, Stanislav Lazarev, Nancy Y Lee, Yang Lei, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Anna Zhai, Ajay Zheng
Affiliation: DYN'R Medical System, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Tianjin Medical University Cancer Institute&Hospital, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Managing tumor motion during pencil beam scanning proton therapy remains challenging. This study investigated the feasibility and dosimetric benefits of Free-Breathing Respiratory-Gated Deliv...
Authors: Himanshu Bhat, Bruce Lewis Daniel, Junghoon Lee, Michael B. Roumeliotis, Ehud J. Schmidt, Ravi Seethamraju, Khadija Sheikh, Pan Su, Akila N. Viswanathan
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Siemens Medical Solutions USA Inc., Stanford Medical School, Department of Cardiology, Johns Hopkins University
Abstract Preview: Purpose: To perform frequent MRI during EBRT and brachytherapy (BT) to evaluate RT-induced fibrosis and remnant tumor changes, identified using ultrashort echo-time (UTE) and multiparametric (mpMRI), ...
Authors: Elizabeth L. Covington, Robert T. Dess, Charles S. Mayo, Michelle L. Mierzwa, Dan Polan, Jennifer Shah, Claire Zhang
Affiliation: University of Michigan, Department of Radiation Oncology, University of Michigan
Abstract Preview: Purpose: Auto-segmentation improves contour consistency and standardization in radiation therapy but may introduce variations from current practices, potentially impacting treatment outcomes and toxic...
Authors: Prabhu C. Acharya, Hassan Bagher-Ebadian, Stephen L. Brown, James R. Ewing, Mohammad M. Ghassemi, Benjamin Movsas, Farzan Siddiqui, Kundan S Thind
Affiliation: Michigan State University, Oakland University, Henry Ford Health
Abstract Preview: Purpose: Accurate T1 quantification using T One by Multiple Read Out Pulse (TOMROP) sequences is essential for physiological assessments in dynamic-contrast-enhanced (DCE) MRI and T1 mapping studies. ...
Authors: Bingqi Guo, Ping Xia
Affiliation: Cleveland Clinic
Abstract Preview: Purpose:
Spatially fractionated radiation therapy (SFRT) delivers a “GRID” or “lattice” of high and low doses to tumors to increase tumor control, minimize normal tissue damage, and preserve the im...
Authors: Ling Chen, Alexei V. Trofimov, Yi Wang, Dufan Wu
Affiliation: Massachusetts General Hospital, MGH
Abstract Preview: Purpose:
Selecting gaze angles of the eye is an important part of set-up of proton therapy for ocular tumors, ensuring that the treatment beam could irradiate the tumor while maximally sparing impo...
Authors: Ming Chao, Karyn A Goodman, Yang Lei, Tian Liu, Jing Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose: Real-time volumetric MRI is essential for motion management in MRI-guided radiotherapy (MRIgRT), yet acquiring high-quality 3D images remains challenging due to time constraints and motion ar...
Authors: Pouya Azarbar, Nima Kasraie, Mahsa Shahrbabki Mofrad, Peyman Sheikhzadeh
Affiliation: UT Southwestern Medical Center, Shahid Beheshti University of Medical science, Imam Khomeini Hospital Complex,Tehran University of Medical Sciences, Tehran University of Medical Science
Abstract Preview: Purpose: PET imaging become crucial in diagnosing and managing various diseases, but its key limitation is the lack of detailed anatomical information. Integrating CT-scans with PET images enhances cl...
Authors: Pouya Azarbar, Nima Kasraie, Peyman Sheikhzadeh
Affiliation: UT Southwestern Medical Center, Shahid Beheshti University of Medical science, Imam Khomeini Hospital Complex,Tehran University of Medical Sciences
Abstract Preview: Purpose: Positron Emission Tomography (PET) is crucial for diagnosing and monitoring diseases due to its functional imaging capabilities. However, its high cost, significant radiation exposure, and li...
Authors: Seth Amofa, Erli Chen, Samuel A. Einstein, Ekinadoese Imudia Frias, Nupur Karmaker, Yinus Kawthara, Dulguun Myagmarsuren, Travis C. Salzillo, Joseph Weygand, Afua A. Yorke
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, University of Washington, Federal University Oye-Ekiti, Cheshire Medical Center, Dartmouth College, Penn State College of Medicine, Dept. of Medical Physics and Biomedical Engineering, Gono Bishwabidyalay, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Virginia Tech Carilion School of Medicine
Abstract Preview: Purpose: Recent developments in the medical physics job market have made it increasingly difficult for radiotherapy centers, particularly in rural areas, to recruit qualified therapeutic medical physi...
Authors: Oluyemi Bright Aboyewa, KyungPyo Hong, Daniel Kim
Affiliation: Department of Radiology, Northwestern University
Abstract Preview: Purpose: While non-Cartesian MRI is desirable for fast imaging with high spatial resolution and robustness to motion, it requires long post-processing times. Preconditioning with an adequate density c...
Authors: Stephen M. Avery, Izabella L. Barreto, Oi-Wai Chau, Cesar Della Biancia, Beata Gontova Bernat, Amanda M. Jackson, Rao Khan, Eugene P. Lief, Osama R. Mawlawi, Wilfred F. Ngwa, Christopher F. Njeh, Peter Allan Sandwall, William Swanson, Joseph Weygand, Afua A. Yorke
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, VA Medical Center, Johns Hopkins University, Mayo Clinic, Champion Cancer Center, Howard University, UT MD Anderson Cancer Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, University of Washington, University of Florida College of Medicine, Washington University in St Louis, Emory University, University of Pennsylvania, OhioHealth, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: To assess needs of medical physicists working in low-and-middle-income countries (LMICs)
Methods: A survey was developed by AAPM’s Global Needs Assessment Committee (GNAC) in partnership w...
Authors: Michael Dohopolski, Jiaqi Liu, Hao Peng, Robert Timmerman, Zabi Wardak, Haozhao Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
This study introduces a gradient-based radiomics framework to enhance outcome prediction in Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR) for brain metastases...
Authors: Enhui Chang, Yunfei Dong, Yifei Hao, Chengliang Jin, Shengsheng Lai, Yi Long, Mengni Wu, Yulu Wu, Ruimeng Yang, Zhenyu Yang, Yue Yuan, Lei Zhang, Wanli Zhang, Yaogong Zhang
Affiliation: Duke Kunshan University, Department of Radiology, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Macrotrabecular-Massive Hepatocellular Carcinoma (MTM-HCC) is one type of liver cancer showed minimum image signature for accurate non-invasive diagnosis. This study aims to develop and evalu...
Authors: Cheng-Chieh Cheng, Jeffrey P Guenette, Yajun Li, Bruno Madore, Lei Qin
Affiliation: Brigham and Women's Hospital, National Sun Yat-sen University, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Pilot tone (PT), a compact RF sensor, has been integrated into clinical practice for motion detection. Prior studies proposed mapping PT signals to head positions using a calibration step tha...
Authors: Davide Brivio, Lia Carroll, Juliane Daartz, Jan PO Schuemann, Piotr Zygmanski
Affiliation: Massachusetts General Hospital, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: We employ High-Energy Current (HEC) detectors for real-time monitoring of proton beams at conventional to FLASH dose rates. This would help overcome the need for fast and accurate dosimeters ...
Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Courtney Bosse Stanley, Dennis N. Stanley, Sean Xavier Sullivan, Natalie N. Viscariello
Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: CBCT-guided online adaptive radiation therapy (OART) with Ethos for stereotactic accelerated partial breast irradiation (APBI) can mitigate inter-fraction variation, leading to dosimetric adv...
Authors: So Hyun Ahn, Chris Beltran, Byongsu Choi, Jeong Heon Kim, Jin Sung Kim, Bo Lu, Justin Chunjoo Park, Bongyong Song, Jun Tan
Affiliation: Mayo Clinic, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Ewha Medical Research Institute, Ewha Womans University College of Medicine, UC San Diego, Yonsei University College of Medicine
Abstract Preview: Purpose:
Cone-beam computed tomography (CBCT) is widely used in IGRT for patient positioning but suffers from low resolution and poor soft tissue contrast. Synthetic CT (sCT) generated from CBCT ad...
Authors: Yu Gao, Lei Xing, Siqi Ye
Affiliation: Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) scans are often the only option for non-coplanar radiation therapy to prevent potential mechanical collisions. However, the consecutive angular occlusion of pr...
Authors: Rex A. Cardan, Carlos E. Cardenas, John B Fiveash, Joel A. Pogue, Richard A. Popple, Farnaz Rahim Li, Rodney J. Sullivan, Natalie N. Viscariello, Christopher Willey
Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: vBrain radiosurgery toxicity-rate is estimated via clinically-relevant isodose volume (IDV) thresholds according to HyTEC (e.g., V12Gy≤10cc). HyperArcTM (HA) automated planning allows accurat...
Authors: Cheryl Anderson, Lara Best, Amanda Cherpak, Jennifer DeGiobbi, Marc C. LeBlanc, R. Lee MacDonald, Peter R. Martin, Natasha McMaster, Murali Rajaraman, James L. Robar, Lucy Ward, Derek Wilke, Kenny Zhan
Affiliation: Department of Radiation Oncology, QE2 Cancer Centre, Nova Scotia Health
Abstract Preview: Purpose: This work investigates the potential benefit of adaptive planning using the Ethos radiotherapy system (Varian Medical Systems) with direct-dose calculation on HyperSight cone beam CT (CBCT) f...
Authors: Wesley E. Bolch, Chansoo Choi, Chan Hyeong Kim, Suhyeon Kim, Bangho Shin, Yeon Soo Yeom
Affiliation: Hanyang University, University of Florida, 2) Department of Radiation Convergence Engineering, Yonsei University
Abstract Preview: Purpose: Task Group 103 of International Commission on Radiological Protection (ICRP) recently released new-generation adult and pediatric mesh-type reference computational phantoms (MRCPs) via ICRP P...
Authors: Mark Ashamalla, Renee Farrell, Jinkoo Kim, Kartik Mani, Xin Qian, Samuel Ryu, Yizhou Zhao
Affiliation: Stony Brook Medicine, Stony Brook University Hospital
Abstract Preview: Purpose: Adaptive planning is increasingly used in head and neck radiation therapy due to factors like tumor response or changes in patient anatomy. However, methods such as resimulation or offline re...
Authors: Hilary P Bagshaw, Mark K Buyyounouski, Serdar Charyyev, Xianjin Dai, PhD, Yu Gao, Thomas R. Niedermayr, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose: Real-time transrectal ultrasound imaging is the gold standard for needle placement and treatment planning of real-time based-ultrasound-based high dose-rate (HDR) prostate brachytherapy. Cumu...
Authors: Cecelia Brewington, Connor Edwards Miles All Leska-Kent, Kyrillos Grace, Katherine Hyde, Sabee Molloi, Shiva Mostafavi, Liqiang Ren, Alireza Shojazadeh, Justin Truong
Affiliation: Department of Radiology, UT Southwestern Medical Center, University of California, Irvine, University of Texas Southwestern
Abstract Preview: Purpose: To retrospectively assess image quality in coronary CT angiography (CCTA) using a patient-specific post-trigger delay (PTD) protocol, developed using half of the injection time plus a dispers...
Authors: John M. Boone, Andrew M. Hernandez, Paul E. Kinahan, Michael F. McNitt-Gray, Jeffrey H. Siewerdsen, Ali Uneri
Affiliation: University of California, Johns Hopkins Univ, UT MD Anderson Cancer Center, David Geffen School of Medicine at UCLA, University of Washington, UC Davis Health
Abstract Preview: Purpose: Measuring image quality (IQ) in large clinical databases, such as the Medical Imaging and Data Resource Center (MIDRC), is challenging due to the inherent complexity of image content and the ...
Authors: Philip Blumenfeld, Jon Feldman, Yair Hillman, Michael Marash, Aron Popovtzer, Alexander Pryanichnikov, Shimshon Winograd, Marc Wygoda, Vered Zivan
Affiliation: Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), P-Cure Ltd./Inc., Sharett Institute of Oncology, Hadassah Medical Center, Hebrew University of Jerusalem
Abstract Preview: Purpose:
Image-guided adaptive proton therapy (IGAPT) allows tailored dose adjustments to account for anatomical and physiological changes during treatment. Recent efforts have developed a cost-eff...
Authors: Nicholas Borges, Steven Brown, Jerimy C. Polf
Affiliation: H3D, inc, Massachusetts General Hospital, M3D, Inc
Abstract Preview: Purpose: To evaluate the potential of using real-time imaging and dose measurement to find weak spots and leaks in bedside shielding systems during diagnostic or interventional fluoroscopic procedures...
Authors: Salman M. Arnab, Yves Chevalier, Samuel Gagné, Adrian F. Howansky, Luc Laperrière, Xiangyi Wu, Wei Zhao
Affiliation: Stony Brook Medicine, Analogic Canada
Abstract Preview: Purpose: A direct-indirect dual-layer flat-panel-detector (DI-DLFPD) is under development for patient motion artifact-free contrast-enhanced digital mammography (CEDM). DI-DLFPD comprises a direct fro...
Authors: Xun Jia, Heng Li, Wen Li, Devin Miles, Daniel Sforza, Lingshu Yin, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: FLASH therapy holds great potential to revolutionize radiotherapy by minimizing toxicities of normal tissues. The extraordinarily high dose rate of FLASH proton beam makes precise delivery to...
Authors: Minbin Chen, Gang Liu, Manju Liu, Weiwei Sang, Pulin Sun, Mingyuan Ye, Fang-Fang Yin, Lihua Zhang, Haiming Zhu
Affiliation: Jiahui International Hospital, Radiation Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: This study aims to evaluate the effects of varying the number of arcs on treatment plans created using Volumetric Modulated Arc Therapy (VMAT) for Lattice radiotherapy (LRT).
Methods: Thre...
Authors: Samuel L. Brady, Joseph G. Meier
Affiliation: Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose:
To establish noise reference levels for our pediatric hospital.
Methods:
Water equivalent diameter (Dw) and image noise was automatically measured by using a global noise algorithm i...
Authors: Jaydev K. Dave, Krzysztof R Gorny, Chunming Gu, Nicholas J. Hangiandreou, Gina K. Hesley, Myung-Ho In, Zaiyang Long, Aiming Lu, Christin A. TiegsHeiden
Affiliation: Mayo Clinic
Abstract Preview: Purpose:
MR-guided focused ultrasound (MRgFUS) enables precise tumor ablation with real-time MR-thermometry guidance. Our practice is exploring the potential use of Feraheme (Ferumoxytol), a superp...
Authors: Wei Luo, Cameron Thayer-Freeman, Yifeng Zhao
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky
Abstract Preview: Purpose: Real-time Kilovoltage (kV) imaging has emerged as a powerful clinical aid, providing high-precision localization of moving targets during treatment. However, the Megavoltage (MV) treatment be...
Authors: Sang Hyun Cho, Sandun Y. Jayarathna, Amrit Kaphle
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: To assess the effectiveness of various nanoscale models of gold nanoparticle (GNP)-laden cells for Monte Carlo (MC) studies of GNP-mediated radiation dose enhancement/DNA damage.
Metho...
Authors: Angela J Da Silva, Andrew Groll, Manoj Narayanan, Jeffrey Schmall, Sanchit Sharma, Timothy Pok Chi Yeung
Affiliation: Reflexion Medical Inc,, RefleXion Medical
Abstract Preview: Purpose: PET-based biology-guided radiotherapy (BgRT) is a radiation therapy technique that uses PET imaging to deliver tracked dose to the tumor in real-time. We characterized the delivery accuracy o...
Authors: Mauricio Acosta, Zachary Fellows, Alonso N. Gutierrez, Noah S. Kalman, Kristen A. McConnell, Rob Rohe, Andrew J. Wroe, Sreenija A Yarlagadda
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose:
Beam selection is crucial in proton therapy to ensure optimal physical and biological dose conformity to the target while maximizing sparing of normal tissue. This work investigates the im...
Authors: Hajee Reyaz Ali Sahib, Sangeeta Hazarika, Muthukumaran Manavalan, Jaswin Raj, Daya Nand Sharma, Seema Sharma, Subramani Vellaiyan
Affiliation: AIIMS NCI Jhajjar, PTW North America Corporation, All India Institute of Medical Sciences
Abstract Preview: Purpose:
Purpose is to investigate the effect of extended source-to-imager distances (SID) on the resolution of VMAT patient-specific quality assurance (PSQA) in portal dosimetry (PD).
Methods:<...
Authors: Spencer Behr, Joseph Grudzinski, Youngho Seo, Jaehoon Shin, Yiran Wang, Frederick J. Wilson
Affiliation: University of California San Francisco, University of California, San Francisco, Voximetry, Inc., Voximetry, Inc
Abstract Preview: Purpose: Voxel-level imaging-based dosimetry enables a significant improvement in accurate and personalized treatment planning in radiopharmaceutical therapy, potentially leading to optimized disease ...
Authors: Mireille Conrad, Cédric De Marco, Marie Fargier-Voiron, Maud Jaccard, Oscar Matzinger, Anthony Nagy, Stéphane Nevesny, Nicolas Joel Lionel Perichon
Affiliation: Clinique De Genolier
Abstract Preview: Purpose: Real-time tracking is implemented on Radixact by detecting the target position with 2D-kV image either directly (for lung tumors), or indirectly (using fiducials as surrogates), and by adapti...
Authors: Marissa Brown, Geoffrey D. Clarke, Luke Norton
Affiliation: University of Texas Health Science Center at San Antonio
Abstract Preview: Purpose: To evaluate how different learning strategies affect convolutional neural network (CNN) estimates of the liver's intravoxel incoherent motion (IVIM) parameters.
Methods: A 3-stage U-Net wa...
Authors: Samuel L. Brady, Kevin Chen, Joseph G. Meier
Affiliation: University of Cincinnati, Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose: Conebeam-CT (CBCT) acquisition protocols typically do not distinguish between adults and pediatrics. In collaboration with a fluoroscopically-guided interventional (FGI) manufacturer, new, do...
Authors: Benjamin J. Sintay, Caroline Vanderstraeten, David B. Wiant
Affiliation: Fuse Oncology, Cone Health
Abstract Preview: Purpose: The Joint Commission (JC) mandates that healthcare organizations establish and evaluate staff competencies to ensure safe and effective patient care. In the context of increasing sub-speciali...
Authors: Andreea Dimofte, Maksym Sharma, Weibing Yang, Timothy C. Zhu
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose:
To assess the effectiveness and dosimetric impact of utilizing a knowledge-based planning model for GI site-specific plans.
Methods:
Six knowledge-based planning models were develope...
Authors: Ibtisam Almajnooni, Elisabeth Weiss, Lulin Yuan
Affiliation: Virginia Commonwealth University
Abstract Preview: Purpose: We developed a deep learning neural network (DLNN) to predict the risk of radiation-induced esophagitis (RE) during lung cancer radiation therapy based on the spatial dose distribution, for t...
Authors: Takahiro Kato, Teiji Nishio, Masataka Oita, Robabeh Rahimi, Yuki Tominaga, Yushi Wakisaka
Affiliation: University of Maryland, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University, Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Medical Physics Laboratory, Division of Health Science, Osaka University Graduate School of Medicine, Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
Abstract Preview: Purpose: This study evaluated dose verifications and lateral penumbra improvements for scanned proton therapy plans with and without a multi-leaf collimator (MLC) under various air gaps.
Methods: E...
Authors: Laura Buchanan, Samantha G. Hedrick, Stephen L. Mahan, Isabella Pfeiffer, Chester R. Ramsey
Affiliation: Thompson Proton Center
Abstract Preview: Purpose: Proton therapy plans can be highly sensitive to both anatomical changes and positional errors, making the acquisition of Quality Assurance CT (QACT) images a routine clinical practice during ...
Authors: Ndey Badjan, Chris Beasley, Issack Boru, Josh Joyner, Erica Owenby, Scott H. Robertson, Nicholas Said
Affiliation: Duke University Health System
Abstract Preview: Purpose:
To design MRI-visible laterality markers to boost patient safety by minimizing errors in laterality and subsequent procedures.
Methods:
The markers were made using commercially avail...
Authors: Krishnendu Saha
Affiliation: Cleveland Clinic Foundation
Abstract Preview: Purpose: The goal is to improve quantitative accuracy of a Maximum-a-posteriori expectation maximization (MAPEM) reconstruction of SPECT phantom images by optimizing Gibbs prior parameters.
Methods...
Authors: Clemens Grassberger, David (Bo) McClatchy, Harald Paganetti
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Massachusetts General Hospital
Abstract Preview: Purpose: While randomized controlled trials (RCTs) are the gold standard for demonstrating efficacy, nearly 50% of late-stage clinical trials fail to meet their endpoint. Tools to study the design of ...
Authors: Davide Brivio, Erno Sajo, Ryan Williams, Piotr Zygmanski
Affiliation: University of Massachusetts Lowell, Brigham and Women's Hospital, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: To develop a non-invasive 3D in-vivo dosimetry tool exploring the relationship between positron annihilations and dose per voxel using Monte Carlo simulation. The Positron Guided Radiation Th...
Authors: Beatriz Allyne Dia Carandang, Chitho P Feliciano, Teresa Sy-Ortin
Affiliation: Department of Physical Sciences and Mathematics, University of the Philippines Manila, Health Physics Research Section, Atomic Research Division, Department of Science and Technology-Philippine Nuclear Research Institute (DOST-PNRI), Graduate School, University of Santo Tomas
Abstract Preview: Purpose: To investigate the X-ray radiation-induced bystander effect (RIBE), where unirradiated cells mimic the responses of directly irradiated cells, in MCF-7 breast cancer cells in vitro to underst...
Authors: María Fernández, Inés Flores, Nuria Montero, Manuel Ruiz, Francisco San Miguel
Affiliation: Hospital Central de la Defensa 'Gómez Ulla', Hospital Central de la Defensa "Gomez Ulla", CSVE, Hospital Central de la Defensa 'Gómez Ulla', CSVE
Abstract Preview: Purpose:
During external radiotherapy treatments in the prostate, there can be PTV movements between fractions and during each treatment fraction. In a typical prostate treatment in our institution...
Authors: Wendy Siman, Wei Zhou
Affiliation: University of Colorado Anschutz Medical Campus, School of Medicine
Abstract Preview: Purpose:
To compare the image quality and radiation dose of 3D cone-beam CT modes of a mobile C-arm and an O-arm unit for intraoperative imaging.
Methods:
A 50-µm tungsten wire was imaged at ...
Authors: James M. Balter, Alexander Moncion, Ikechi S Ozoemelam
Affiliation: University of Michigan
Abstract Preview: Purpose: Sequential dual-energy cone beam computed tomography (DE-CBCT) integrated with an online adaptive platform could potentially improve soft tissue visualization for more accurate anatomical del...
Authors: Vibha Chaswal, Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Yongsook C. Lee, William Romaguera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose: To report machine performance of our superficial radiation therapy unit (SRT-100 Vision, Sensus Healthcare, Boca Raton, FL) for the first three years after commissioning of the unit.
Metho...
Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder
Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida
Abstract Preview: Purpose: Early-stage NSCLC patients undergoing SBRT often die due to intercurrent illnesses. However, prediction of overall survival (OS) remains crucial due to the risk of disease recurrence. This st...
Authors: Salim Balik, Nguyen Phuong Dang, Hualin Zhang
Affiliation: Radiation Oncology, Keck School of Medicine of USC
Abstract Preview: Purpose: An accurate and convenient monitoring of radiation dose delivery during treatment is essential for ensuring patient safety and treatment efficacy. This project aims to develop innovative algo...
Authors: Daisuke Kawahara, Yoichi Watanabe
Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Radiation Oncology, University of Minnesota Medical School
Abstract Preview: Purpose: Combination therapies with immunotherapy (IT) and radiotherapy (RT) are widely used, but the optimal IT timing is unclear. This study leverages a computational cellular automaton (CA) model, ...
Authors: Jue Jiang, Aneesh Rangnekar, Shiqin Tan, Harini Veeraraghavan
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Weill Cornell Graduate School of Medical Sciences
Abstract Preview: Purpose: Clinicians often use information from FDG-PET and CT to interpret and delineate gross tumor (GTVp) and nodal (GTVn) volumes for radiotherapy planning in head and neck (HN) cancer patients. He...
Authors: Qihui Lyu, Javier Caravaca Rodriguez, Youngho Seo, Ke Sheng, Jingjie Yu
Affiliation: University of California San Francisco, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Simultaneous broad-energy imaging is critical for many theragnostic applications, but the current Single-Photon Emission Computed Tomography (SPECT) can only image low energy photons with ...
Authors: Ryan Clark, Jon Cornelisse, Kenny Guida, Anthony Magliari, Lesley Rosa, Megan Smith, Shane R Stecklein
Affiliation: Office of Medical Affairs, Varian, A Siemens Healthineers Company, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Post-mastectomy radiation therapy (PMRT) can pose a challenge for planners of all levels of experience. For cases where 3D conformal therapy yields undesirable results (i.e., dose heterogenei...
Authors: Akihiro Haga, Ren Iwasaki, Kenya Kusunose, Makoto Miyake, Kenji Moriuchi, Yasuharu Takeda, Hidekazu Tanaka, Hirotsugu Yamada
Affiliation: Department of Cardiovascular Medicine, Nephrology, and Neurology Graduate School of Medicine, University of the Ryukyus, Graduate School of Biomedical Sciences, Tokushima University, Tokushima university, Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Department of Cardiology, Tenri Hospital, Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Division of Heart Failure, Department of Heart Failure and Transplant, National Cerebral and Cardiovascular Center
Abstract Preview: Purpose: Device dependency is a significant challenge in medical AI, potentially limiting generalization performance. This study aimed to develop a robust deep learning model for predicting left ventr...
Authors: Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Sudharsan Madhavan, Nikhil Mankuzhy, Nishant Nadkarni, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Voxel-based analysis (VBA) requires accurate topology-preserving inter-patient deformable image registration (DIR). This study assessed whether guiding a DIR method with geometric priors of t...
Authors: Evan Barber, Gloria P. Beyer, Matthew J. Daniels, Callum Hartley, Jordi Saez, Philip Wheeler
Affiliation: TrueNorth Medical Physics, Department of Radiotherapy Physics, Velindre University NHS Trust, Department of Radiation Oncology, Hospital Clinic de Barcelona, Medical Physics Services, LLC
Abstract Preview: Purpose: To quantify inter-system and inter-layer dosimetric leaf gap (DLG) variations in Halcyon/Ethos multileaf collimators (MLCs) using custom sweeping gap tests, and to evaluate implications for c...
Authors: Angela Gearhardt, Stephen F. Kry, Christopher Ryan Peeler, Julianne M. Pollard-Larkin
Affiliation: The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences; The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Electronic medical devices (EMDs) must be carefully managed in radiation oncology to prevent radiation-induced device malfunction. Only one EMD, pacemaker/defibrillator, has a recommended pro...
Authors: Alexei V. Chvetsov, Sunan Cui, Sunyoung Jang, Robert D. Stewart
Affiliation: University of Washington and Fred Hutchinson Cancer Center, Penn State College of Medicine, University of Washington
Abstract Preview: Purpose: To evaluate spatial variation of relative biological effectiveness (RBE) in COMS (Collaborative Ocular Melanoma Study) eye plaques with low energy 125I and 103Pd photon sources as a function ...
Authors: Daylin Barroso, Chris Beekman, Wesley E. Bolch, Natalia Estefania Carrasco-Rojas, Robert Joseph Dawson, Walter Murfee, Harald Paganetti, Andrew Robert Sforza, Julia D. Withrow
Affiliation: Massachusetts General Hospital - Harvard Medical School, Massachusetts General Hospital, University of Florida
Abstract Preview: Purpose: To develop methods for quantifying the interaction of radiation with blood in the mouse whole body (MOBY) phantom for dosimetric applications. The most important of these are modeling the dis...
Authors: Saree Alnaghy, Owen Thomas Dillon, Sean P Hood, Paul J. Keall, Ricky O'Brien, Tess Reynolds
Affiliation: Image X Institute, Faculty of Medicine and Health, The University of Sydney, University of Wollongong, Medical Radiations, School of Health and Biomedical Sciences, RMIT University
Abstract Preview: Purpose: Photon Counting Detectors (PCDs) have been demonstrated to improve resolution, contrast and lesion detectability in fan-beam CT. There is naturally a desire to bring these improvements to Con...
Authors: James Ward, Anzi Zhao
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: This study investigates the impact of tissue-equivalent attenuator materials, the region of interest (ROI) size, and the orientation of the attenuator positioning on the measured signal-to-no...
Authors: Wesley A. Belcher, Robert A. Corns, Jae Won Jung, Matthew S Peach, Swarup Sharma
Affiliation: The University of North Carolina at Chapel Hill, East Carolina University Brody School of Medicine
Abstract Preview: Purpose: GammaTiles are a novel intracranial brachytherapy approach designed to directly deliver radiation therapy to residual or recurrent brain tumors following resection. Despite their promising th...
Authors: Xun Jia, Youfang Lai
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Ultrahigh dose rate FLASH (>40 Gy/s) radiotherapy (RT) has attracted significant attention. The mechanism remains unclear, hindering clinical translation. This study investigated the behavior...
Authors: Peter Jermain, Ying Niu, Abdul Rashid, Yuan Yuan, Mohammad Zarenia
Affiliation: Medstar Georgetown University Hospital, MedStar Georgetown University Hospital, Department of Radiation Medicine, MedStar Georgetown University Hospital
Abstract Preview: Purpose: ZAP-X is a self-shielded radiosurgery system that utilizes a linac-based isocentric technique and a compact gyroscopic gantry design. While it provides a large solid angle for beam orientatio...
Authors: Jimmy Caudell, Eduardo G. Moros, Nour Nasser, Gage H. Redler, George Yang
Affiliation: Moffitt Cancer Center
Abstract Preview: Purpose: Dosimetric evaluation of PTV margin reduction for Head and Neck(H&N) sequential boost plans using the Ethos online adaptive radiotherapy(oART) system to investigate the tradeoff in decreased ...
Authors: Denise Dunn, Scott R. Floyd, Tyler V. Kay, Anna Lynnette-Price, Eric L. Martin, Stepan Mikhailov, Taylor Nguyen, Mark Oldham, Victoria J. P. Radosova, Zachary J. Reitman, Ramona Rodriguiz, Andrew Thompson, William Wetsel, Seth Wilcox, Ying Wu
Affiliation: Duke University Mouse Behavior Core, Department of Physics, Duke University, Medical Physics Graduate Program, Duke University, Duke University Medical Physics Program, Duke University, Duke University Mouse Behavioral and Neuroendocrine Analysis Core Facility, Department of Radiation Oncology, Duke University Medical Center
Abstract Preview: Purpose: FLASH radiation therapy (RT) shows promise for reducing normal tissue damage, though its mechanisms remain unclear. Using an in-vivo model with the High Intensity Gamma-ray Source (HIGS) lina...
Authors: Yuqi Yang, Fang-Fang Yin
Affiliation: Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Reactive oxygen species (ROS) are unstable molecules which play important roles in the cellular process after Flash radiotherapy. The rapid changes in ROS levels during treatment may provide ...
Authors: Niki Fitousi, Stanley Thomas Fricke, Anna Romanyukha
Affiliation: Qaelum NV, Children's National Hospital
Abstract Preview: Purpose:
To identify opportunities for improvement through investigation of outliers in exam dose length product (DLP) and patients receiving high cumulative doses (CED), in the context of our “ped...
Authors: Michalis Aristophanous, Laura I. Cervino, Maria F. Chan, Puneeth Iyengar, Hsiang-Chi Kuo, Nancy Y Lee, Xiang Li, Seng Boh Gary Lim, Usman Mahmood, Jean M. Moran, Jason Ocana
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To determine the limits of iodine concentration detection (LOD) and quantification (LOQ) in dual-energy computed tomography using a 3D printed phantom while considering different background, ...
Authors: Harald Keller, Iymad Mansour, Jeff D. Winter
Affiliation: Princess Margaret Cancer Centre
Abstract Preview: Purpose: The growing number of adaptive therapy applications is motivating image segmentation and direct dose calculation on CBCT. The purpose of this investigation is to evaluate the recently release...
Authors: John T Barrett, Chulhaeng Huh, Farshad Mostafaei, Michelle Rocque, Austin Sanders
Affiliation: Department of Radiation Oncology, Medical College of Georgia, Augusta University, Department of Radiation Oncology, Augusta University, Georgia Radiation Therapy Center, Wellstar-MCG Health
Abstract Preview: Purpose: This study involved the use of Accuray’s TPS (Precision) and RayStation TPS for planning TBI treatments. TBI was delivered using Accuray’s Radixact machine, and dose calculation algorithm, do...
Authors: Meghan Lubner, Aria M. Salyapongse, Teva Shapiro, Scott D. Slavic, Timothy P. Szczykutowicz, Giuseppe Toia, Zhye Yin
Affiliation: GE HealthCare, Departments of Radiology and Medical Physics, University Wisconsin-Madison, GE Healthcare, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison, University of Wisconsin Madison, Department of Radiology
Abstract Preview: Purpose:
To compare iodine quantification on a prototype deep silicon photon-counting detector (PCD) CT and conventional clinical energy-integrating (EID) dual-energy (DE) CT.
Methods:
A phan...
Authors: ChangSeon Kim, Andrew Lukban, Mario Serrano-Sosa, Ching-Ling Teng, Nadia M. Vassell
Affiliation: Northwell, Mount Sinai Beth Israel
Abstract Preview: Purpose:
The flexible nature of ballistic gelatin and 3D printed material such as PLA lend themselves to phantom studies in brachytherapy. While these materials can allow for easy simulation of cat...
Authors: Xiangli Cui, Zilei Fu, Man Hu, Wanli Huo, Xiaoqing Wu, Jianguang Zhang, Yingying Zhang
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Department of Oncology, Xiangya Hospital, Central South University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences
Abstract Preview: Purpose:
Using Stable Diffusion to generate images of the knee in different disease states can enrich the medical imaging database and inject new vitality into the field of medical imaging analysis...
Authors: Nesrin Dogan, Panagiota Galanakou, Robert Kaderka
Affiliation: University of Miami, Sylvester Comprehensive Cancer Center, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose:
To develop knowledge-based treatment planning (KBP) for volumetric modulated arc therapy (VMAT) in chest wall treatments with regional nodal involvement. Given the challenges posed due to ...
Authors: Mojtaba Behzadipour, Suman Gautam, Tianjun Ma, Ikchit Singh Sangha, Bongyong Song, William Song, Kumari Sunidhi
Affiliation: UC San Diego, Virginia Commonwealth University
Abstract Preview: Purpose: This study aims to develop a knowledge-based voxel-wise dose prediction system using a convolutional neural network (CNN) for high-dose-rate (HDR) prostate brachytherapy and to evaluate its p...
Authors: Ruiming Chen Edmondson, Darwin Abraham Garcia, James A. Kavanaugh, Joseph John Lucido
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Characterize the dose response and reproducibility of a low-dose film for 6 MV photon beam and assess the film’s energy dependence between kV and MV energies.
Methods: A single 8’x10’ LD-V...
Authors: Hassan Bagher-Ebadian, Anthony J. Doemer, Ryan Hall, Joshua P. Kim, Bing Luo, Benjamin Movsas, Humza Nusrat, Kundan S Thind
Affiliation: Department of Physics, Toronto Metropolitan University, Henry Ford Health
Abstract Preview: Purpose: This study investigates the development and feasibility of local LLM-based agents to automate radiotherapy treatment planning, aiming to improve planning efficiency and consistency, while pre...
Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang
Affiliation: Duke University Medical Center
Abstract Preview: Purpose:
This study aims to leverage large language model (LLMs) to develop a human-in-the-loop agentic framework, enhancing the efficiency of treatment planning in radiotherapy.
Methods:
A L...
Authors: Victoria Susan Ainsworth, Stephen M. Avery, Serhii Brovchuk, Thomas Brown, Sean A. Dresser, Matthew D. Goss, Viktor M. Iakovenko, Kelly Kisling, Nataliya Kovalchuk, Robert F. Krauss, Wilfred F. Ngwa, Jatinder R. Palta, Julie A. Raffi, Peter Allan Sandwall, Natalka Suchowerska, William Swanson, Shada J. Wadi-Ramahi, Ruslan Zelinskyi
Affiliation: Allegheny Hospital, Johns Hopkins University, Virginia Commonwealth University, Stanford University, O.O. Shalimov National Institute of Surgery and Transplantology, Department of Radiation Oncology, UT Southwestern Medical Center, School of Physics, The University of Sydney, MaineHealth, University of California, San Diego, Duke University, Emory University, University of Pennsylvania, University of Pittsburgh Medical Center, Medical Physics Department, Medical center of Yuriy Spizhenko, OhioHealth, University of Massachusetts Lowell, St. Francis Hospital
Abstract Preview: Purpose: The AAPM International Council, in collaboration with Help Ukraine Group (HUG) and Ukrainian Association of Medical Physicists (UAMP), developed a novel hybrid year-long training course to as...
Authors: Christopher P. Favazza, Andrea Ferrero, Taylor Froelich, Forrest Linch, Scott Thompson
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Photon counting detector (PCD) CT is a promising tool to enhance pre-procedural planning and intra-procedural guidance for prostate artery embolization due to its unsurpassed ultra-high spati...
Authors: Yan Dai, Jie Deng, Christopher Kabat, Weiguo Lu, Ying Zhang, Hengrui Zhao
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
MRI-guided adaptive radiotherapy (MRgART) using MR-LINAC systems offers significant advantages for liver cancer, enabling superior tumor delineation and online plan adaptation. However, ma...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care
Abstract Preview: Purpose: To develop an accurate predictive temporal model for the movement of Dynamic Collimation System (DCS) trimmers during collimated proton pencil beam scanning (PBS) deliveries using log data. T...
Authors: Awens Alphonse, Nebi Demez, Brian P. Laffey, Shyam Pokharel, Suresh Rana, Nishan Shrestha
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: The Imaging Ring is a mobile digital X-ray system capable of producing 2D planar X-rays, fluoroscopy, and 3D Cone-Beam Computed Tomography (CBCT) images. This study aimed to evaluate the long...
Authors: Geoffrey D. Clarke, Laura A. Cox, Alexander J Moody, Peter W Nathanielsz, Bowen Yang
Affiliation: Wake Forest University School of Medicine, University of Texas Health Science Center at San Antonio, Texas Biomedical Research Institute
Abstract Preview: Purpose:
Recent studies show diagnostic value of myocardial strain analysis for left ventricular (LV) function using cardiac magnetic resonance imaging (CMR). RV function analysis is more challengi...
Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital
Abstract Preview: Purpose: To evaluate the performance of KBP models for hypo-fractionated prostate and pelvic lymph nodes (LN) VMAT plans.
Methods: A KBP model (TUH KBP) was developed in Eclipse treatment planning ...
Authors: Waleed Mutlaq Almutairi, Ke Colin Huang, Vishwas Mukundan, Christopher F. Njeh, Oluwaseyi Oderinde, Yong Yue
Affiliation: Purdue University, Indiana University School of Medicine, Department of Radiation Oncology, Advanced Molecular Imaging in Radiotherapy (AdMIRe) Research Laboratory, Purdue University, West Lafayette, Indiana, USA
Abstract Preview: Purpose:
This study aimed to develop a machine learning (ML) model for early prediction of chemoradiotherapy (CRT) response in order to enhance personalized treatment selection for oral or orophary...
Authors: Shusen Jing, Qihui Lyu, Dan Ruan, Ke Sheng, Qifan Xu
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: Metallic implants can significantly distort sinograms, leading to severe artifacts in computed tomography (CT) reconstructions. Reconstructing CT images containing metal is fundamentally an i...
Authors: Afrouz Ataei, Xinhui Duan, Mi-Ae Park, Liqiang Ren
Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University
Abstract Preview: Purpose:
Photon-counting CT (PCCT) has become commercially available recently, offering significant potential to enhance patient care. However, it also introduces unique challenges. One such challe...
Authors: Giavanna Luisa Jadick, Patrick J La Riviere
Affiliation: University of Chicago
Abstract Preview: Purpose: We assess two multi-measurement acquisition schemes for material decomposition with x-ray phase-contrast imaging (XPCI); demonstrating for the first time that multi-distance imaging can match...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Iowa, Iowa Health Care
Abstract Preview: Purpose:
To perform end-to-end treatment planning and delivery verification of energy-specific collimated treatments optimized to achieve the maximum obtainable high-dose conformity using the dynam...
Authors: Rachel B. Ger, Xun Jia, Youfang Lai, Todd R. McNutt, Xingyi Zhao
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Radiotherapy (RT) plays an essential role for head and neck (HN) cancer treatment but often results in xerostomia due to salivary gland damage. It is important to mechanistically model the ra...
Authors: Wamied T. Abdel-Rahman, Iqbal AlAmri, Lma Alahmare, Ghada Aldosary, Marwa Alghamdi, Lujain Aljadou, Yarah Alkhulaif, Abdullah A. Alshreef, Ohoud Alsubaie, Hoton Alsufyani
Affiliation: Loma Linda University Medical Center, Princess Nourah Bint Abdulrahman University, King Fahad Specialist Hospital, KAMC- Ministry of National Guard Health Affairs, SQCCCRC, KASCH- Ministry of National Guard Health Affairs
Abstract Preview: Purpose: The shortage of qualified medical physicists in many developing countries is due to multiple factors such as lack of awareness or access to graduate and residency training programs. An outrea...
Authors: Ali Ajdari, Alice Bondi, Thomas R. Bortfeld, Gregory Buti, Xinru Chen, Zhongxing Liao, Antony John Lomax, Ting Xu
Affiliation: The University of Texas MD Anderson Cancer Center, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Paul Scherrer Institut, ETH Zurich
Abstract Preview: Title: Addressing Imaging and Biomarker-driven Uncertainty in Machine Learning-based Radiotherapy Outcome Prediction
Alice Bondi, Gregory Buti, Antony Lomax, Thomas Bortfeld, Xinru Chen, Ting Xu, Z...
Authors: Junwen Liu, Mengzhen Wang, Ning Wen, Jifeng Xiao, Fuhua Yan, Yanzhao Yang, Xuekun Zhang, Zheyu Zhang
Affiliation: Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai Jiaotong University, The SJTU-Ruijin-UIH Institute for Medical Imaging Technology, Shanghai Jiaotong University Schoo of Medicine
Abstract Preview: Purpose:This study aims to develop and evaluate a large language model (LLM) fine-tuned to generate consistent and accurate impressions from imaging findings. Additionally, the study investigates the ...
Authors: Robert A. Dahl
Affiliation: Mayo Foundation
Abstract Preview: Purpose: To develop tools to simplify/accelerate the quality assurance testing of the Mobetron mobile linear accelerator and increase safety when moving it to different OR’s.
Methods: The Mobet...
Authors: Ming Dong, Carri K. Glide-Hurst, Qisheng He, Anudeep Kumar, Alex Singleton Kuo, Joshua Pan, Chase Ruff, Nicholas R. Summerfield
Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Recent evidence highlights the importance of incorporating cardiac substructures (CS) into treatment planning for thoracic cancers, however current segmentation methods are limited to a singl...
Authors: MacKenzie Rachelle Coon, Justin Geise, Judith Noemi Rivera, Matthew L. Scarpelli, Jessica Leigh Veenstra, Chandler Zaugg
Affiliation: Purdue University, Indiana University
Abstract Preview: Purpose: Glioblastoma (GBM) is among the most aggressive and treatment-resistant cancers due to its immunosuppressive tumor microenvironment. Immunotherapy holds promise for GBM treatment, but its eff...
Authors: Michael M Folkerts, Miriam Krieger, Pierre Lansonneur, Gerard Paquet, Petar Penchev, Christoph Schuy, Yuri Simeonov, Uli Weber, Klemens Zink
Affiliation: GSI Helmholtzzentrum fuer Schwerionenforschung, Institute of Medical Physics and Radiation Protection (IMPS), University of Applied Sciences, Varian Medical Systems
Abstract Preview: Purpose:
Ultra-high dose-rate proton irradiation may spare the healthy tissue (FLASH-effect). The 3D-range-modulator (3D-RM) method reduces the treatment time compared to conventional IMPT and can ...
Authors: Hongjing Sun, Weibing Yang, Timothy C. Zhu, Yifeng Zhu
Affiliation: University of Pennsylvania
Abstract Preview: Purpose: This study aims to compare the commissioning results of TrueBeam and Halcyon linear accelerators with Monte Carlo (MC) simulations conducted using TOPAS. The ultimate goal is to leverage MC s...
Authors: Stephen R. Bowen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Jiajie Wang, Shouyi Wang, Faisal Yaseen, Han Zhou
Affiliation: Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Fred Hutchinson Cancer Center, University of Texas at Arlington
Abstract Preview: Purpose: Predicting the effects of the spatial-temporal tumor response to chemoradiation can assist in adjusting radiation dose and support clinical decision-making in radiotherapy. A multi-instance l...
Authors: Tess Armstrong, Nema Bassiri, Alonso N. Gutierrez, Michael Kasper, Natalia Lutsik, Eric Mellon, Kathryn E. Mittauer, Siamak P. Nejad-Davarani, Shyam Pokharel, Suresh Rana, Hui Wang, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Miami Cancer Institute, Baptist Health South Florida, ViewRay, Inc., Miami Cancer Institute, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Department of Radiation Oncology, University of Miami
Abstract Preview: Purpose: Radiation treatments on the MR-linac (MRL) enable daily acquisition of anatomical and physiological images for adaptive treatment planning. The apparent diffusion coefficient (ADC) estimated ...
Authors: Caroline Cheney, Nicole M. Lafata, Zaiyang Long, Dustin W. Lynch, Erin B. Macdonald, Andy Madore, Douglas E. Pfeiffer, Colin Schaeffer, Alexander W. Scott
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, UVA Health, Duke University Health System, Mayo Clinic, Henry Ford Health, Boulder Community Health, Varian, Cedars-Sinai Medical Center
Abstract Preview: Purpose: This work evaluates the significance of performing established radiography automatic exposure control (AEC) tests by comparing testing methodology, outcomes, and failure rates across multiple...
Authors: Yunfei Dong, Dongyang Guo, Jiongli Pan, Tao Peng, Caiyin Tang, Zhenyu Yang, Fang-Fang Yin, Lei Zhang, Tianyi Zhang, Yaogong Zhang
Affiliation: Duke Kunshan University, Department of Radiology, Taizhou People’s Hospital Affiliated to Nanjing Medical University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: This study aims to improve the accuracy of CT-based diagnosis of thyroid cancer by developing a hybrid model that integrates Convolutional Neural Networks (CNNs) with Long Short-Term Memory (...
Authors: Tyler J Bradshaw, Sharon M Castellino, Steve Y Cho, David Hodgson, Bradford S Hoppe, Kara M Kelly, Andrea Lo, Sarah Milgrom, Xin Tie
Affiliation: Department of Radiation Oncology, University of Toronto, Department of Radiology, University of Wisconsin, University of Colorado Anschutz, Department of Medical Physics, University of Wisconsin, Department of Radiation Oncology, Mayo Clinic, Department of Radiation Oncology, BC Cancer, Vancouver Center, Department of Radiology, University of Wisconsin - Madison, Roswell Park Comprehensive Cancer Center, Emory University School of Medicine
Abstract Preview: Purpose: Clinical target volume (CTV) delineation for involved-site radiation therapy (ISRT) in Hodgkin lymphoma (HL) is time-consuming due to the need to analyze multi-time-point PET/CT scans co-regi...
Authors: Ming Chao, Thomas Chum, Tenzin Kunkyab, Yang Lei, Tian Liu, Richard G Stock, Hasan Wazir, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
This study aims to develop effective strategies for multi-organ segmentation of pelvic cone-beam computed tomography (CBCT) images based on transformer models to facilitate adaptive radiat...
Authors: Laurence Edward Court, Alexandra Olivia Leone, Zhongxing Liao, Saurabh Shashikumar Nair, Joshua S. Niedzielski, Ramon Maurilio Salazar, Ting Xu
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Radiation Pneumonitis (RP) predictive models often rely on clinical and DVH parameters, but multiomic features from CT imaging and 3D dose distributions from various regions could provide add...
Authors: Steve B. Jiang, Mu-Han Lin, Yu-Chen Lin, Austen Matthew Maniscalco, Dan Nguyen, David Sher, Xinran Zhong
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, UT Dallas
Abstract Preview: Purpose:
Sequential boost radiotherapy (RT) poses a challenge in allocating dose across multiple plans while protecting organs at risk (OARs). Clinicians must decide whether OAR sparing should occu...
Authors: Blessing Chinelo Akah, Brad Barhorst, Daniel W. Neck, David J. Perrin, Chad Robertson, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: To evaluate the performance and radiation isocenter of Elekta and Varian linear accelerator using Aktina Isopoint.
Methods: The Aktina Isopoint was used to measure the physical and radiati...
Authors: Jiayi Chen, Shaolei Li, Fuhua Yan, Yingli Yang, Jie Zhang
Affiliation: Department of Radiology, Ruijin Hospital, Institute for Medical Imaging Technology, Ruijin Hospital, Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai United imaging Healthcare Advanced Technology Research Institute, Department of Radiation Oncology, Ruijin Hospital
Abstract Preview: Purpose: The aim of this exploratory study is to investigate the feasibility of establishing a model to explore tissue component heterogeneity using multidimensional diffusion magnetic resonance imagi...
Authors: Yeona Cho, Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Jihun Kim, Jin Sung Kim, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, Memorial Sloan Kettering Cancer Center, Yonsei University
Abstract Preview: Purpose: We hypothesized that combining clinical, imaging, and radiotherapy dose-distribution features could increase predictive model accuracy in radiation-induced severe acute esophagitis (SAE) in e...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Sarah E. McKenney, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose:
While wide coverage (160 mm) CT scanners can image whole organs (e.g. heart, brain, kidneys, etc.) in one axial scan, the peripheral regions of the field of view (along z) suffer from cons...
Authors: Hassan Bagher-Ebadian, Ahmed I Ghanem, Joshua P. Kim, Chengyin Li, Rafi Ibn Sultan, Kundan S Thind, Dongxiao Zhu
Affiliation: Wayne State University, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health
Abstract Preview: Purpose: Accurate segmentation of the Left Anterior Descending (LAD) artery in free-breathing 3D treatment planning CT is crucial for radiotherapy but remains challenging due to its small size, comple...
Authors: Nicholas Joseph Casteloes, Brian T Collins, Sean P Collins, Shiva K. Das, Panayiotis Mavroidis, Michael Repka, Simeng Suy
Affiliation: University of South Florida, University of North Carolina
Abstract Preview: Purpose: To correlate four rectal symptoms with the dose to rectum in patients, who received SBRT with Cyberknife for prostate cancer. Also, to fit those dosimetric and outcome data by using a normal ...
Authors: Nicholas Joseph Casteloes, Brian T Collins, Sean P Collins, Shiva K. Das, Panayiotis Mavroidis, Michael Repka, Simeng Suy
Affiliation: University of South Florida, University of North Carolina
Abstract Preview: Purpose: To correlate two urinary symptoms with dose to bladder and urethra in patients who received SBRT with Cyberknife. Also, to use a normal tissue complication (NTCP) model to fit the dosimetric ...
Authors: Gregory A Azzam, Danielle Cerbon, Laura Huang, Panayiotis Mavroidis, Diana Molinares, Stuart E Samuels, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center, University of Miami Sylvester Comprehensive Cancer Center, Mount Vernan Rehabilitation Medicine Associates, Department of Radiation Oncology, University of Miami, University of North Carolina
Abstract Preview: Purpose: This study aims at performing a normal tissue complication probability (NTCP) modeling by fitting the doses to the skin, sternocleidomastoid (SCM) muscle and subcutaneous tissue (subcut) stru...
Authors: Md Mainul Abrar, Yujie Chi
Affiliation: University of Texas at Arlington, Department of Physics, University of Texas at Arlington
Abstract Preview: Purpose: Healthcare 5.0, proposed in 2021, includes interpretable healthcare analysis as a core component. Achieving this requires the application of explainable artificial intelligence (XAI) to overc...
Authors: Stephanie Bennett, Ross I. Berbeco, Guillaume Bort, Needa Brown, Lena Carmes, Sandrine Dufort, Michael John Lavelle, Geraldine Le Duc, Francois Lux, Toby Morris, Zeinaf Muradova, Andrea Protti, Olivier Tillement
Affiliation: University de Lyon, NH TherAGuIX, University of Massachsetts Lowell and Dana-Farber Cancer Institute Boston, Department of Radiation & Cellular Oncology, University of Chicago, University of Central Florida, Department of Radiation Oncology, Dana-Farber/Brigham and Women’s Cancer Center, Harvard Medical School, NH TherAguix, Universite de Lyon, Brigham and Women's Hospital, Dana-Farber Cancer Institute
Abstract Preview: Purpose: AGuIX is a theranostic Gd-based nanoparticle currently under phase-2 clinical testing where patients receive 2-3 doses at 1-week intervals prior to imaging and irradiation. AGuIX-Bi is a new ...
Authors: Samuel L. Brady, Shruti Hegde, Alexander Knapp, Usman Mahmood, Joseph G. Meier, Elanchezhian Somasundaram, Zachary Taylor
Affiliation: Cincinnati Children's Hospital Medical Ctr, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Cincinnati Children's Hospital Medical Center, Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose:
To assess how two benchmark multi-organ CT segmentation models respond to varying image noise levels.
Methods:
This study utilized the pediatric CT dataset from The Cancer Imaging Ar...
Authors: Mavlonbek Khomidov, Jong-Ha Lee
Affiliation: Department of Biomedical Engineering, Keimyung University, Department of Computer Engineering, Keimyung University
Abstract Preview: Purpose: In this research, we aim to estimate blood pressure using remote photoplethysmography (rPPG) signal extracted from facial video. This method provides non-invasive and contactless, continuous ...
Authors: Peymon Ghazi
Affiliation: MALCOVA Inc.
Abstract Preview: Purpose: To develop a near scatter‐free breast CT imaging system that expands coverage of the posterior breast anatomy and enhances contrast resolution for solid masses and microcalcifications, while ...
Authors: Victor B. Kassey, Maciej M. Kmiec, Periannan Kuppusamy, Ryan C. O'Connell, Sergey V. Petryakov, Conner Ubert
Affiliation: Dartmouth College
Abstract Preview: Purpose: High-resolution magnetic field uniformity is essential for quantitative and pre-clinical MRI research. Imaging uniformity is affected by the B0 field, which can be corrected using manual or a...
Authors: David P. Adam, William T. Hrinivich, Taoran Li, Alexander Lu, Michael Salerno, Alejandro Sisniega, Boon-Keng Kevin Teo
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, University of Pennsylvania
Abstract Preview: Purpose: Cone beam CT (CBCT)-guided online adaptive radiotherapy (ART) is of growing interest, with recent improvements in image quality provided through larger detector panels and fast gantry rotatio...
Authors: Vikas Aragam, Edward Castillo, Richard Castillo, Yingxuan Chen, Yevgeniy Vinogradskiy, Lydia J. Wilson
Affiliation: Thomas Jefferson University, Emory University, University of Texas at Austin
Abstract Preview: Purpose: 4DCT-based ventilation imaging (4DCT-ventilation) has been innovatively applied in radiotherapy treatment planning to minimize doses to functional portions of the lung, known as functional av...
Authors: Kevin M Brom, Josep Chorro Bas, RosaAnna Chorro Bas, Andres Climent Rubio, Jaydev K. Dave, Tobias Kummer, Larissa Shiue, Donald J Tradup
Affiliation: Mayo Clinic, Prehospital Critical Care Training Group
Abstract Preview: Purpose: To design and evaluate the functionality of a vascular flow phantom for contrast-enhanced ultrasound imaging (CEUS).
Methods: A microcontroller-generated signal was amplified by a cust...
Authors: Emily Helen Hayes, Luke Maloney
Affiliation: University of Florida
Abstract Preview: Purpose: To determine the dosimetric water equivalency of polylactic acid (PLA) and commercial 3D printing resin using electron stopping power as a surrogate, for use in radiochromic film calibration ...
Authors: Jeff Boob, Jaydev K. Dave, Tim Minch, Bhavyata Tanna
Affiliation: Dr. Ronald E. McNair Academic High School, Mayo Clinic, CurveBeam AI
Abstract Preview: Purpose: To estimate effective doses associated with different imaging protocols for hip imaging with a cone beam CT (CBCT) scanner specifically designed for weight-bearing acquisitions.
Methods: A...
Authors: Slade J. Klawikowski, Natalya V. Morrow, Haidy G. Nasief, Eric S. Paulson, An Tai, Hualiang Zhong
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Gafchromic film is commonly used for quality assurance in SRS/SBRT. However, its application in low-dose measurements, such as monitoring doses on cardiac implantable electronic devices—where...
Authors: Larry A. DeWerd, Ahtesham Ullah Khan
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison
Abstract Preview: Purpose: Total body irradiation (TBI) technique uses high energy photon beams with extended source-to-surface distances (SSDs) to irradiate the entire patient to prepare them for bone marrow or stem c...
Authors: Mary Gronberg, Kelly Kisling, Ana Maria Marques da Silva
Affiliation: University of California, San Diego, The University of Texas Southwestern Medical Center, Pontifical Catholic University of Rio Grande do Sul
Abstract Preview: Purpose: To evaluate the current status of online teaching in medical physics and identify effective active learning strategies for global medical physics education.
Methods: A scoping review was c...
Authors: Brankica Andelic, Young-Bin Cho, Tara M. Gray, Andrew Robert Hadfield, Hakan Nordstrom
Affiliation: Elekta, Cleveland Clinic
Abstract Preview: Purpose: Spatially Fractionated Radiotherapy (SFRT) requires highly modulated dose distribution inside a tumor volume optimized using sets of planning structure of spheres in a lattice arrangement. To...
Authors: Chih-Wei Chang, Junbo Peng, Richard L.J. Qiu, Justin Roper, Xiangyang Tang, Tonghe Wang, Huiqiao Xie, Xiaofeng Yang, David Yu
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Emory Univ, Emory University, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Limited-angle dual-energy (DE) cone-beam CT (CBCT) is considered a promising solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, ...
Authors: Amy Fitzpatrick, Kim Howard, Julius G. Ojwang, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: This study evaluates the dosimetric advantages and workflow improvements of the CyberKnife S7 Precision Treatment Planning System (TPS) with the VOLO optimizer for stereotactic radiosurgery (...
Authors: Siju C. George, Alonso N. Gutierrez, Vivek Mishra, Ranjini P. Tolakanahalli
Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute
Abstract Preview: Purpose: This presentation focuses on optimizing dosimetry in RPT clinics by tackling initial setup challenges and ensuring the accuracy of SPECT/CT imaging for dosimetry. It will address the qualific...
Authors: Anthony J. Doemer, Ian Gallagher, Yimei Huang, Jeff A. Riess, Kundan S Thind, Bo Zhao
Affiliation: Henry Ford Health
Abstract Preview: Purpose: Stereotactic body radiation therapy (SBRT) is commonly used for early-stage lung cancer. While pre-treatment CT captures some tumor motion, it may not fully represent intra-fraction motion du...
Authors: Chia-Lung Chien, Wen C. Hsi, Faraz Kalantari, Pouya Sabouri, Man Yam
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose:
Reducing treatment delivery time is critical to improving patient throughput and minimizing the risk of intrafraction motion, which can compromise treatment accuracy. This study identifies...
Authors: Seungtaek Choi, Laurence Edward Court, Eun Young Han, Yusung Kim, Hunter S. Mehrens, Tucker J. Netherton, Shiqin Su
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Automated treatment planning is gaining traction for its enhanced consistency and efficiency. A key challenge, however, lies in the inability of neural network dose predictions directly trans...
Authors: Xiaohu Li, Jianjun Shen, Guozhi Zhang, Sihua Zhong, Jingjie Zhou
Affiliation: United Imaging Healthcare
Abstract Preview: Purpose:
Visualization of carotid artery vessel wall on computed tomography angiography (CTA) imaging is challenging. This study aims to develop a novel post-processing technique, black-blood compu...
Authors: Weiliang Du
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Winston-Lutz (WL) tests are often used to localize the radiation isocenter of a linac. The selection of gantry and collimator angles can affect the accuracy of the resulting isocenter. The ef...
Authors: Panagiotis Iliopoulos, Marios Myronakis, Kyriaki Theodorou
Affiliation: Medical Physics Department, Medical School, University of Thessaly
Abstract Preview: Purpose: To estimate individualized absorbed dose at Organs at Risk (OARs) from kV Cone Beam CT (CBCT) imaging in the pelvic area, prior radiotherapy, and assess excess risk for secondary malignancies...
Authors: Wookjin Choi, Michael Dichmann, Adam Dicker, Nilanjan Haldar, Yingcui Jia, Nicole L Simone, Eugene Storozynsky, Yevgeniy Vinogradskiy, Maria Werner-Wasik
Affiliation: Thomas Jefferson University, 9Department of Radiation Oncology, Thomas Jefferson University
Abstract Preview: Purpose: Cardiotoxicity remains a significant limitation for lung cancer patients treated with radiotherapy. Pre-radiotherapy cardiac conditions increase the probability of patients developing cardiot...
Authors: Manju Liu, Ning Wen, Fuhua Yan, Yanzhao Yang, Zhenyu Yang, Haoran Zhang, Lei Zhang, Yajiao Zhang
Affiliation: Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy where precise segmentation of tumors and adjacent vessels is crucial for effective treatment planning. This study dev...
Authors: Blessing Akinro, Soumyanil Banerjee, Ming Dong, Carri K. Glide-Hurst, Prashant Nagpal, Chase Ruff, Nicholas R. Summerfield, Timothy P. Szczykutowicz
Affiliation: Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Departments of Radiology and Medical Physics, University Wisconsin-Madison, Department of Radiology, University of Wisconsin-Madison, Department of Computer Science, Wayne State University, Department of Human Oncology
Abstract Preview: Purpose: Radiation dose to coronary arteries (CAs) during thoracic radiotherapy (RT) is linked to cardiotoxicity. However, precise CA delineation for avoidance is limited by image quality and CA compl...
Authors: Hao Chen, Kai Ding, Xiaoyu Hu, Xun Jia, Heng Li, Devin Miles
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Accurately delivering radiation dose is critical in intensity-modulated proton therapy (IMPT), where intrafraction motion management plays a pivotal role. Our proton therapy system equipped x...
Authors: Esteban Arzaga-Barajas, Paola Jazmin Guadarrama Huerta, Jose Alejandro Jimenez, Guerda Massillon-JL, Maria Adela Poitevin-Chacón, Alejandro Rodriguez-Laguna
Affiliation: UNAM, Medica Sur
Abstract Preview: Purpose: To perform patient-specific quality assurance (PSQA) tests for four SBRT treatments of patients diagnosed with vertebral, ilium, pelvic lymph node and lung tumors.
Methods: MAGIC gel consi...
Authors: Karyn A Goodman, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Qian Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Beth Israel Deaconess Medical Center
Abstract Preview: Purpose: Accurate motion management in MRI-guided radiotherapy (MRIgRT) relies on real-time volumetric MRI to track intra-fractional anatomical changes. Dense k-space sampling, while capable of produc...
Authors: Yifei Hao, Chengliang Jin, Wenxuan Li, Bing Luo, Tao Peng, Yulu Wu, Fang-Fang Yin, Yue Yuan, Lei Zhang, Ruojun Zhou
Affiliation: School of Future Science and Engineering, Soochow University, Electrical and Computer Engineering Graduate Program, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Federated learning is a patient privacy-protecting technique that has recently been applied in the medical field. This study aims to evaluate the performance of several deep learning networks...
Authors: Yasaman Anbari, Srinivas Cheenu Kappadath, Benjamin P. Lopez, Armeen Mahvash, Ali Yousefi
Affiliation: University of Houston, UT MD Anderson Cancer Center
Abstract Preview: Purpose: Patient-demographics-model-based liver volumetry is well-established for determining the future liver remnant following hepatectomy. We used gold-standard CT liver segmentation to validate th...
Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu
Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center
Abstract Preview: Purpose: The purpose of this work is to describe the design and development of a newly developed upright-geometry dedicated breast CT system and to quantitatively and qualitatively evaluate its imagin...
Authors: Belen Juste, Choonsik Lee, Matthew Mille, Rafael Miró, Sergio Morato Rafet, Agustin Santos, Gumersindo Verdú
Affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Universitat Politècnica de València, Servicio de Radiofísica y Protección Radiológica, Consorcio Hospitalario Provincial de Castellón, National Cancer Institute
Abstract Preview: Purpose: To evaluate the differences in CT scan radiation dose estimation between personalized dose reconstruction, based on real patient CT images, and generalized phantom-based dose calculations.
Authors: Wesley S. Culberson, Aleksandra Ilina, Brian W Pogue, Matthew Reed, Connor Strainis, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel
Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin–Madison, University of Wisconsin-Madison, University of Wisconsin - Madison
Abstract Preview: Purpose: FLASH radiotherapy reduces skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR), while preserving damage to tumor tissue. The FLASH effec...
Authors: Chao Guo, Xinhua Li, Michael F. McNitt-Gray, Di Zhang, Yifang (Jimmy) Zhou
Affiliation: UCLA, David Geffen School of Medicine at UCLA, Cedars-Sinai Medical Center
Abstract Preview: Purpose: The objective was to quantify the liver fat volume fraction (FVF) with virtual monochromatic imaging (VMI) using photon-counting CT (PCCT) and dual energy CT (DECT).
Methods: A custom desi...
Authors: Saad Bin Saeed Ahmed, Marcos Feijoo, Wazir Muhammad, Charles Shang, Naseem Ud Din
Affiliation: South Florida Proton Therapy Institute, Miami Cancer Institute, Blue Physics LLC, Florida Atlantic University
Abstract Preview: Purpose: This study introduces a novel approach for patient-specific quality assurance in proton beam therapy, utilizing new plastic scintillator detectors with high temporal resolutions to create det...
Authors: Laura Buchanan, Samantha G. Hedrick, Stephen L. Mahan, Isabella Pfeiffer, Chester R. Ramsey, Taylor Ransom
Affiliation: Thompson Proton Center, University of Tennessee
Abstract Preview: Purpose: Proton pencil beam scanning can reduce normal tissue dose but is highly sensitive to setup, anatomical changes, and range variations. These uncertainties may compromise target coverage and or...
Authors: Osama R. Mawlawi, Yiran Sun
Affiliation: RICE University, UT MD Anderson Cancer Center
Abstract Preview: Purpose: Conventional PET reconstruction methods often produce noisy images with artifacts due to data/model mismatches and inconsistencies. Recently, deep learning-based conditional denoising diffusi...
Authors: Marcos Feijoo, Mamoru Ichiki, Tatsuya Maeda, Tatsuhiro Makino, Tomonori Megumi, Tadashi Nakabayashi, Yukino Nakata, Shuichi Ozawa, Daishi Takayama
Affiliation: Hiroshima High-Precision Radiotherapy Cancer Center, Blue Physics LLC, Imamura General Hospital, Accuray Inc.
Abstract Preview: Purpose: This study aims to accurately measure the leaf open time (LOT) of the multi-leaf collimator (MLC) in tomotherapy using an advanced plastic scintillator detector (PSD) with high time resolutio...
Authors: Hilary P Bagshaw, Mark K Buyyounouski, Xianjin Dai, PhD, Praveenbalaji Rajendran, Lei Xing, Yong Yang
Affiliation: Department of Radiation Oncology, Stanford University, Massachusetts General Hospital, Harvard Medical School
Abstract Preview: Purpose: Artificial intelligence (AI)-driven methods have transformed dose prediction, streamlining the automation of radiotherapy treatment planning. However, traditional approaches depend exclusivel...
Authors: David Alcorta, Joseph Farina, Timothy Haystead, Yiping He, Philip Hughes, David Loiselle, Marybeth Nedrud, Victoria J. P. Radosova, Jianpeng Yu
Affiliation: Duke University Department of Pharmacology and Cancer Biology, Medical Physics Graduate Program, Duke University, Duke University Department of Medicine, Duke University, Duke University Pharmacology and Cancer Biology, Duke University School of Medicine, Duke Cancer Institute
Abstract Preview: Purpose: Targeted radiopharmaceuticals have become of widespread interest in the scientific community given their ability to detect and treat metastatic disease. We aim to validate the use of novel ch...
Authors: Ashok Bhandari, Andrew Joseph Fanning, Kyle J. Gallagher, Brendan Graff, Christopher Jenkins, Kyuhak Oh, Ying Yan, Su-Min Zhou
Affiliation: University of Nebraska Medical Center
Abstract Preview: Purpose: This study aimed to design a robust experimental setup to ensure accurate dose delivery using ultra-high-dose-rate for small animal experiments by conducting dosimetric evaluations prior to a...
Authors: John Ginn, Zhuoyun Huang, Yongbok Kim, Ke Lu, Chunhao Wang, Yibo Xie, Zhenyu Yang, Jingtong Zhao
Affiliation: Duke University, Duke Kunshan University
Abstract Preview: Purpose: This study aims to develop and validate a machine learning model for predicting V60%, a critical dosimetric metric in LINAC-based Single-Isocenter-Multiple-Targets (SIMT) stereotactic radiosu...
Authors: Leslie Harrell, Sanjay Maraboyina, Romy Megahed, Maida Ranjbar, Xenia Ray, Pouya Sabouri
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), University of California San Diego
Abstract Preview: Purpose: Real-time adaptive radiation therapy (ART) dynamically modifies patients’ treatment plan during delivery to account for anatomical and physiological variations. Addressing ART planning time v...
Authors: Ozan Cem Guler, William Silva Mendes, Sangbo Oh, Cem Onal, Lei Ren, Apurva Singh, Phuoc Tran
Affiliation: University of Maryland School of Medicine, Baskent University Faculty of Medicine, Department of Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: To predict metastasis-free survival (MFS) for patients with prostate adenocarcinoma treated with androgen deprivation therapy and external radiotherapy using clinical factors and radiomics ex...
Authors: Ali Hosni, Oleksii Semeniuk, Andrea Shessel, Teo Stanescu
Affiliation: Princess Margaret Hospital, Princess Margaret Cancer Centre, Brown University Health
Abstract Preview: Purpose: To report on early clinical experience with a two-phase radiotherapy approach for esophageal cancer patients, utilizing CBCT-based conventional C-arm linear accelerator radiotherapy and MR-gu...
Authors: Katja M. Langen, Mark McDonald, Bill Stokes, Yinan Wang, Suk Whan (Paul) Yoon
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Effective dose management in high-risk re-irradiation (ReRT) patients entails early, detailed special physics consultation (SPC) to mitigate risks from cumulative radiation dose. SPCs have tr...
Authors: James Knight II, Joshua Misa, Damodar Pokhrel, William St Clair, Eddy S Yang
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Highly-heterogenous sieve-like dose distribution via SFRT to large/bulky tumors (≥6 cm) could enhance tumor cell-death via both direct/indirect cell-kill mechanisms. Adding highly-conformal S...
Authors: Hua-Chieh Shao, You Zhang, Ruizhi Zuo
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Cone-beam CT (CBCT) provides on-board patient anatomy for image guidance and treatment adaptation in radiotherapy. However, to compensate for respiration-induced anatomical motion, motion-res...
Authors: Eduardo Florian, Osmar Obdulio Hernandez, Otto Hurtarte, Milton Ixquiac, Erick Orlando Montenegro, Franky Eduardo Reyes, Edgar Aparicio Ruiz, Kevin Vega, Vicky de Falla
Affiliation: Liga Nacional Contra el Cancer, Liga Nacional Contra el Cancer/INCAN, Liga Nacional Contra el Cancer / INCAN, Liga Nacional Contra el Cancer and Universidad de San Carlos de Guatemala, Liga Nacional Contra el Cáncer / INCAN
Abstract Preview: Introduccion:
Lattice Radiation Therapy (LRT) is a form of spatially fractionated radiation therapy (SFRT) designed to improve control of large tumors by delivering ablative doses while minimizing ...
Authors: Maria Jose Medrano, Grant Stevens, Liyan Sun, Justin Ruey Tse, Adam S. Wang, Sen Wang
Affiliation: Department of Radiology, Stanford University, GE HealthCare, Stanford University
Abstract Preview: Purpose: Patient exposure to ionizing radiation is a major concern in CT imaging. Size-specific dose estimation methods can prospectively estimate organ-level radiation doses based on patient sizes an...
Authors: Fahad Alam, Douglas A Hoover, Raffi Karshafian, Andrew Loblaw, Lucas Mendez, Lucas Mendez, Gerard Morton, Humza Nusrat, Moti R. Paudel, Mackenzie Smith, Amandeep Tagger, Anton Varlukhin
Affiliation: Odette Cancer Center, Sunnybrook Health Sciences Center, Department of Anesthesiology, Temerty Medicine, University of Toronto, Department of Physics, Toronto Metropolitan University, Department of Radiation Oncology, Temerty Medicine, University of Toronto, Department of Radiation Oncology, London Health Sciences Centre
Abstract Preview: Purpose: Prostate brachytherapy utilization has declined, due in part to limitations seen with in-person training including time and space constraints in the operating room. Virtual reality addresses ...
Authors: Jeremy S. Bredfeldt, Daniel W. Cail, Maria A. Czerminska, Cindy I. Hancox, David Hu, Benjamin Karasko, Claire Keun Sun Park
Affiliation: Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, Brigham and Women's Hospital, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: To develop a robust clinical protocol for in vivo dosimetry in radiotherapy using the myOSLchip Optically Stimulated Luminescent Dosimeter (OSLD) system by performing characterization and eva...
Authors: Salahuddin Ahmad, Imad M. Ali, Zaid Alkalani, Nesreen Alsbou
Affiliation: University of Oklahoma, University of Central Oklahoma, University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: To design and evaluate a 3D-detector for proton CT-imaging and radiography, utilizing volumetric plastic scintillator detector exposed to high-energy therapeutic beams from proton therapy sys...
Authors: Stephen M Corner, Daiki Hara, Jiasen Ma, Robert W Mutter, Mark D. Pepin, Nicholas B. Remmes, Hok Seum Wan Chan Tseung
Affiliation: Mayo Clinic - Rochester
Abstract Preview: Purpose: Proton minibeam radiotherapy (pMBRT) is a form of spatially fractionated radiation therapy leveraging submillimeter beams to improve the therapeutic ratio. We report on collimator design, com...
Authors: Gueorgui Gueorguiev, Kavya Thaniyarasu
Affiliation: University of Bologna, National Centre of Radiobiology and Radiation Protection
Abstract Preview: Purpose: This study investigates the clinical viability of double scattering proton therapy treatment planning for thoracic malignancies using single or multiple treatment fields. The aim of this stud...
Authors: Yussuf A. Abdelal, Junguo Bian, Michael Delafuente, Sebastien A. Gros, Hyejoo Kang, Luke Layman, M Mahesh, John C. Roeske
Affiliation: Department of Radiology and Medical Imaging, Stritch School of Medicine, Loyola University Medical Center, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Johns Hopkins Univ
Abstract Preview: Purpose: This study evaluates the feasibility of optimizing 4DCBCT imaging protocols for gated lung SBRT, by reducing dose while maintaining the image quality required for accurate patient alignment.<...
Authors: Hyejoo Kang, Andrew Keeler, Mathias Lehmann, Jason Patrick Luce, Ha Nguyen, John C. Roeske
Affiliation: Varian Imaging Laboratory, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago
Abstract Preview: Purpose: Markerless tumor tracking (MTT) using dual-energy (DE) subtraction imaging is being considered as a non-invasive method to track tumors during lung cancer treatment. Prior to clinical impleme...
Authors: Teh Lin, Anna Oneil
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Four-dimensional computed tomography(4DCT) is often required to assess organ motions for thoracic and abdominal cancer patients. This study proposes a quality assurance (QA) procedure for two...
Authors: Ali Ammar, Quan Chen, Jingwei Duan, Yi Rong, Nathan Y. Yu, Libing Zhu
Affiliation: Mayo Clinic Arizona, University of Alabama at Birmingham
Abstract Preview: Purpose: Clinical performance of deep learning-based auto-segmentation (DLAS) can degrade over time due to AI “aging” from unseen data input compared to the initial model training data. This study aim...
Authors: Haiqa Arain, Ping Xia, Zhexuan Zhang
Affiliation: Cleveland Clinic
Abstract Preview: Purpose: To quantify water contents and thickness of wet towel (as a flexible bolus) on curved surface dose for partial breast irradiation.
Methods: Two VMAT partial breast plans (3000 cGy in 5...
Authors: Eric C. Ford, Awusi Kavuma, Solomon Kibudde, Lilie Lin, Apollo Muramuzi, Nibedita Paul, Peniel T Twum, Afua A. Yorke
Affiliation: Uganda Cancer Institute, MD Anderson Cancer Center, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Nebraska, Global Communities
Abstract Preview: Purpose: Sub-Saharan Africa accounts for over one-third of global cervical cancer deaths, despite representing only 14% of the world’s female population. At the only RT center in Uganda, prior studies...
Authors: Chih-Chiang Chang, Chingyun Cheng, Ben Durkee, Minglei Kang, Elissa Khoudary, Yangguang Ma, Xuanqin Mou, YuFei Wang, Tengda Zhang, Wang Zhengda
Affiliation: Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, School of Software Engineering, Xi’an Jiaotong University, School of information and communications engineering, Faculty of electronic and information engineering, Xi’an Jiaotong University, Department of Medical Physics, Columbia University, University of Pennsylvania, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: This study presents a voxel-based analysis method based on deformable image registration to accurately quantify respiratory-induced motion and deformation of both targets and organs at risk (...
Authors: Fatemeh Akbari, Deidre Batchelar, Luc Beaulieu, Nathan E. Becker, Juanita Crook, Dakota Mckeown, Matthew Jonathan Muscat, Rowan M. Thomson
Affiliation: Département de physique, de génie physique et d'optique, Université Laval, BC Cancer Agency, UBC, Carleton University, BC Cancer - Kelowna, BC Cancer
Abstract Preview: Purpose:
To study the effects of inter-seed attenuation and tissue inhomogeneities on dose-volume metrics of critical structures in prostate low-dose-rate (LDR) permanent seed implant brachytherapy...
Authors: Afrouz Ataei, Victor Moy, Mark P. Supanich
Affiliation: Rush University
Abstract Preview: Purpose: To evaluate iodine quantification and CT number accuracy in coronary CT angiography (CTA) using standard and ultra-high resolution (UHR) modes of photon-counting CT (PCCT) across different do...
Authors: Rick Holly, Sumudu Katugampola
Affiliation: Gesinger Medical Center, Geisinger Medical Center
Abstract Preview: Purpose:
To quantitatively analyze long term variations in optical density of un-irradiated and irradiated EBT3 radio-chromic films and their effects on dose calibration curves in a clinical settin...
Authors: Zahra Alyani Nezhad, Carrie Bartels, Rachel Bladorn, Sean D. Rose, Kelsey Schluter, Timothy P. Szczykutowicz
Affiliation: Departments of Radiology and Medical Physics, University Wisconsin-Madison, University of Wisconsin Madison, University of Wisconsin-Madison, University of Texas at Houston Medical School, University of Wisonsin-Madison
Abstract Preview: Purpose: Pulmonary embolism is a life-threatening condition, and computed tomography pulmonary angiography (CTPA) is the gold standard for diagnosis. Inadequate contrast enhancement often leads to a h...
Authors: Jeffrey S. Nelson, Raj Kumar Panta, Megan K. Russ, Ehsan Samei
Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: Contrast-enhanced mammography (CEM) enhances tumor detection by utilizing energy-dependent information from iodinated contrast agents. However, there is a lack of quantitative techniques to a...
Authors: Giavanna Luisa Jadick, Patrick J La Riviere, Cailey Riggs
Affiliation: University of Chicago
Abstract Preview: Purpose: We explore the accuracy of physics models for propagation-based x-ray phase-contrast imaging (XPCI) with an eye to future clinical implementation, providing a practical assessment of detectio...
Authors: Arezoo Modiri, Robabeh Rahimi, Akira SaiToh, Amit Sawant
Affiliation: Maryland University Baltimore, University of Maryland, University of Maryland in Baltimore, Department of Computer and Information Sciences, Sojo University
Abstract Preview: Purpose: It has been a longstanding challenge to optimize the daily schedule of radiation treatment rooms toward minimum patient wait times, efficient use of clinical staff and reduced running cost of...
Authors: Lars Ewell, Russell J. Hamilton
Affiliation: Banner University Medical Group, Bannerhealth
Abstract Preview: Purpose: To estimate the variability and predictability of radiation dose as a function of the planning target volume (PTV) size and the anatomical sites of head & neck, brain and prostate.
Methods...
Authors: Mohammad Nazmul Alim, Regina DeWitt
Affiliation: Department of Physics, East Carolina University,, Department of Physics, East Carolina University
Abstract Preview: Purpose: This study quantifies the ability of Luxel (Al₂O₃:C) to measure radiation dose from a Moxtek X-ray source. Key aspects of OSL dosimetry, including OSL curves, dose response, depth dose, and b...
Authors: Guilherme Rosa Ferreira, Dan Giardina, John Karageorgiou, Chris Malone, Allan Thomas
Affiliation: Washington University School of Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine
Abstract Preview: Purpose: Radiation segmentectomy has become a primary strategy in 90Y radioembolization, with localized treated volumes that can include up to two liver segments. The goal is complete pathological nec...
Authors: Chloe DiTusa, Panayiotis Mavroidis, Christopher W. Schneider, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center, University of North Carolina
Abstract Preview: Purpose:
To calculate radiobiological metrics of daily dose delivered for head and neck (HN) patients using the daily cone beam CT (CBCT) to generate a pseudo CT (pCT). Moreover, this work compares...
Authors: Yao Hao, Yuting Peng, Francisco Javier Reynoso, Tianyu Zhao, Xiandong Zhao
Affiliation: Varian, University of South Florida, Washington University School of Medicine, Washington University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: Ultra-high dose-rate (FLASH) dose rate (> 40 Gy/s) may result in a radio-protective effect in healthy tissue compared with conventional dose rate (CDR). This effect has been observed in vivo ...
Authors: Nrusingh C. Biswal, Manas R. Gartia, Maria Iftesum, Sanjit K. Roy, Gyana Ranjan Sahoo, Elnaz Sheikh, Hem D. Shukla, Madhur Srivastava
Affiliation: Department of Chemistry and Chemical Biology, Cornell University, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Mechanical and Industrial Engineering, Louisiana State University
Abstract Preview: Purpose: Prostate cancer incidence and mortality levels in African-American men are the highest among all ethnic groups. This points to the role of biological factors in driving disparate outcomes. He...
Authors: Jon Burns, Andrew Groll, Gopinath Kuduvalli, Thomas Laurence, Manoj Narayanan, Jeffrey Schmall, Sanchit Sharma
Affiliation: RefleXion Medical
Abstract Preview: Purpose: To simplify BgRT testing we have developed techniques that use 3D resin printed structures that can be filled with Ge-68 epoxy. This approach allows the development of highly complex, clinica...
Authors: Hania A. Al-Hallaq, Chih-Wei Chang, Anees H. Dhabaan, Yuan Gao, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Keyur Shah, Sibo Tian, Zhen Tian, Xiaofeng Yang, David Yu, Jun Zhou
Affiliation: Emory University, Whinship Cancer Institute, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Traditional cone-beam computed tomography (CBCT) often requires multiple angular projections, increasing radiation exposure and extending scanning times, which may lead to heightened patient ...
Authors: Mary Feng, Yi Lao, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger
Affiliation: University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, City of Hope National Medical Center, University of California San Francisco, Siemens Medical Solutions USA Inc.
Abstract Preview: Purpose: 4D MRI with high spatiotemporal resolution is vital to characterize the tumor/tumor motion for liver radiotherapy. However, high-quality 4D MRI requires an impractically long scanning time fo...
Authors: Keiichi Jingu, Noriyuki Kadoya, Takafumi Komiyama, Takeru Nakajima, Hikaru Nemoto, Hiroshi Onishi, Masahide Saito, Ryota Tozuka
Affiliation: Department of Radiology, University of Yamanashi, Department of Radiation Oncology, Tohoku University Graduate School of Medicine, Department of Advanced Biomedical Imaging, University of Yamanashi
Abstract Preview: Purpose: We evaluated the accuracy of a new AI-based fully automated planning software in stereotactic body radiotherapy (SBRT) for early-stage lung cancer.
Methods: We collected data from 125 pati...
Authors: Ruiyan Du, He Huang, Mingzhu Li, Ying Li, Hongyu Lin, Wei Liu, Shihuan Qin, Yiming Ren, Hui Xu, Lian Zhang, Xiao Zhang, Zunhao Zhang
Affiliation: Department of Radiation Oncology, Mayo Clinic, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Department of Oncology, The First Hospital of Hebei Medical University
Abstract Preview: Purpose: Monte Carlo (MC) dose calculation is the gold standard in clinical CyberKnife radiation therapy (RT), considering its steep dose gradients and high-freedom non-coplanar beam angles, but extre...
Authors: Steve B. Jiang, Austen Matthew Maniscalco, Dan Nguyen, Chenyang Shen, Jiacheng Xie, Shunyu Yan, Ying Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Although treatment planning systems (TPSs) can handle dose calculation and plan optimization automatically, planning for radiotherapy still requires extensive efforts and expertise from a mul...
Authors: Yi Fan, Andrew Friberg, Costas Koumenis, Kevin Teo, Ioannis I Verginadis, Ledi Wang, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: Glioblastomas (GBM) are aggressive and lethal malignancies characterized by their highly refractory nature, contributing to a five-year survival rate of approximately 7%. Physically, GBM exhi...
Authors: Shreyas Anil, Jason Chan, Arushi Gulati, Yannet Interian, Hui Lin, Benedict Neo, Andrea Park, Bhumika Srinivas
Affiliation: Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, Department of Data Science, University of San Francisco, Department of Radiation Oncology, University of California San Francisco, University of San Francisco
Abstract Preview: Purpose: As Large Language Models (LLMs) continue to evolve, their ability to analyze Electronic Health Record (EHR) notes for clinical decision support expands. Chain of Thought (COT) reasoning, an e...
Authors: Matthew Case, Richard Castillo, Sunil Dutta, Edgar Gelover, Katja M. Langen, Alexander Stanforth, Mingyao Zhu
Affiliation: Emory University
Abstract Preview: Purpose: To evaluate the application of LETd and track-end (TE) objective functions during the optimization of breast proton therapy plans to decrease the risk of lung toxicity and rib fractures.
M...
Authors: Yifei Hao, Ting Huang, Wenxuan Li, Xiang Li, Manju Liu, Rong Liu, Tao Peng, Yulu Wu, Fang-Fang Yin, Lei Zhang, Yaogong Zhang, Jiangtao Zhu
Affiliation: Duke University, Department of Radiology, The Second Affiliated Hospital of Soochow University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: This study investigates the alterations in structure-function coupling (SC-FC) networks in Parkinson’s disease (PD) patients, focusing on region-specific disruptions and compensatory mechanis...
Authors: Weixing Cai, Laura I. Cervino, Qiyong Fan, Yabo Fu, Tianfang Li, Xiang Li, Jean M. Moran, Hai Pham, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: AAPM Task Group Report 273 emphasizes the importance of rigorous validation to ensure the generalizability and robustness of machine learning-based clinical tools before their implementation ...
Authors: Alexander Baikalov, Luke Connell, Nolan M. Esplen, Michele M. Kim, Stephen F. Kry, Emil Schueler, Hayden Scott, Ryan Sun, Paige A. Taylor, Uwe Titt
Affiliation: The University of Texas MD Anderson Cancer Center, University of Pennsylvania, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: to develop an affordable, portable device for accurately measuring FLASH dose rates from protons, electrons, and photons. 4 detectors were utilized to measure the temporal structure of proton...
Authors: Sandeep Panwar Jogi, Nancy Lee, Ricardo Otazo, Ramesh Paudyal, Qi Peng, Akash Shah, Amita Shukla-Dave, Can Wu
Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center
Abstract Preview: Purpose: Quantitative T1ρ imaging provides enhanced tissue characterization beyond standard T1 and T2 parameters, potentially supporting early-stage longitudinal monitoring of head and neck cancer. Th...
Authors: Salim Balik, Eric Chang, Kristine Garcia, Andrew Islas, Lijun Ma, Zhilei Liu Shen, Elizabeth Zhang-Velten
Affiliation: Radiation Oncology, Keck School of Medicine of USC
Abstract Preview: Purpose: NRG protocols recommend simulating and treating head and neck (HN) cancer patients in a supine position for optimal setup reproducibility. However, certain patients cannot tolerate the supine...
Authors: Daming LI, Jinsen Xie, Zhe Zhang
Affiliation: Peking University Shenzhen Hospital Radiotherapy Department, School of Nuclear Science and Technology, University of South China
Abstract Preview: Purpose: To analyze the actual doses received during radiotherapy for head and neck cancers (HNC) using Velocity, providing insights for adaptive radiotherapy decision-making.
Methods: Thirty-three...
Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital
Abstract Preview: Purpose: Frameless gamma knife (GK) treatments use a thermoplastic mask coupled with high-definition motion management system that utilizes an infrared camera, and a reflective marker placed on the pa...
Authors: Danielle Renee Daiger, Nicholas N. Sperling
Affiliation: University of Toledo, University of Toledo Medical Center
Abstract Preview: Purpose:
To retrospectively evaluate the impact of planned delivery time on plan quality metrics for breath-hold VMAT SBRT thoracic cancer patients.
Methods:
Patients treated for SBRT thoraci...
Authors: Diandra Ayala-Peacock, Junzo Chino, Oana I. Craciunescu, Allison Jones, Kyle J. Lafata, Kim Light, Sheridan G. Meltsner, Jack B Stevens
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Duke University Medical Center
Abstract Preview: Purpose: This study aims to develop an MR-based method that retrospectively correlates longitudinal changes in morphology and physiology for the bulboclitoris and vaginal canal with dose received duri...
Authors: Brankica Andelic, Young-Bin Cho, Tara M. Gray, Bingqi Guo, Andrew Robert Hadfield, Hakan Nordstrom, Jacob Scott, John Suh, Nara Yoon
Affiliation: Adelphi University, Elekta, Cleveland Clinic
Abstract Preview: Purpose: To investigate the biological effect of Spatially Fractionated Radiation Therapy (SFRT) within Gamma-Knife (GK) using retrospective planning for brain metastases patients. This study presents...
Authors: Adebayo Abe, Samuel Olaolu Adeneye, Eben Aje, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Lilian Ekpo, Muhammad Habeebu, Adedayo O. Joseph, Charles S. Mayo, Noah Ndianaobong, Ikechi S Ozoemelam, Margaret Dideolu Taiwo, Godwin Uwagba
Affiliation: University of Michigan, University of Ibadan, University of Lagos, Missouri University of Science and Technology, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre, NSIA-LUTH Cancer Center
Abstract Preview: Purpose:
Head and neck cancers (HNC) present significant challenges in radiotherapy due to complex anatomy and the proximity to critical organs at risk (OARs). These challenges are compounded in na...
Authors: Yan Dai, Jie Deng, Xun Jia, Wen Li
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Cell microstructure information is critical for radiotherapy response assessment. Diffusion MRI (dMRI) offers great potential in deriving cell parameters. Yet parameters estimated in existing...
Authors: Albert Admasu, Kayla Alfonso, Maria de la Luz De Ornelas, Nesrin Dogan, Eric Mellon, Yunze Yang
Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Rotational uncertainties in single-isocenter multi-target (SIMT) stereotactic radiosurgery (SRS) HyperArc treatments can cause additional target displacement, potentially degrading overall pl...
Authors: Laura Buchanan, Samantha G. Hedrick, Stephen L. Mahan, Isabella Pfeiffer, Chester R. Ramsey
Affiliation: Thompson Proton Center
Abstract Preview: Purpose: The CQ Medical kVue Pronumbra Head & Neck (HN) System is a new immobilization device for proton therapy. The mask includes 4 large knobs that attach to the board with built-in shims. These kn...
Authors: Tatsuya Fujisaki, Hiraku Fuse, Shin Miyakawa, Hiroki Nosaka, Masato Takahashi, Kenji Yasue
Affiliation: Ibaraki Prefectural University of Health Sciences
Abstract Preview: Purpose: This study aimed to evaluate the robustness of Jacobian-based and HUchange-based CT ventilation imaging (CTVI) against respiratory amplitude variations using a custom-designed alveolar phanto...
Authors: Zahra Alyani Nezhad, Carrie Bartels, Rachel Bladorn, Sean D. Rose, Kelsey Schluter, Timothy P. Szczykutowicz
Affiliation: Departments of Radiology and Medical Physics, University Wisconsin-Madison, University of Wisconsin Madison, University of Wisconsin-Madison, University of Texas at Houston Medical School, University of Wisonsin-Madison
Abstract Preview: Purpose: This study presents a scientifically quantified case study that underscores the importance of the medical physicist’s contribution to contrast enhancement optimization.
Methods: CT pulmona...
Authors: Joke Binst, Hilde TC Bosmans, Niki Fitousi, Bram Miseur, Dimitar Petrov, Kwinten Torfs, Janne Vignero
Affiliation: Qaelum NV, Department of radiology, UZLeuven, Department of imaging and pathology, KULeuven
Abstract Preview: Purpose: Routine quality monitoring in CT abdomen is crucial for ensuring optimal image quality and patient safety, but the simultaneous evaluation of all aspects of importance is challenging. The pur...
Authors: Jae Won Jung, Daniel Lee
Affiliation: Thomas S. Wootton High School, East Carolina University Brody School of Medicine
Abstract Preview: Purpose: Monkeys have played a key role in enhancing our understanding of the behavior of radioactive materials within living organisms in the field of nuclear medicine. However, detailed dosimetric d...
Authors: Tommaso Frigerio, Joshua Genender, John M. Hoffman, Catherine (Caffi) Meyer
Affiliation: UCLA, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose: Accurate bone marrow segmentation is required for bone marrow dosimetry to monitor for dangers in PSMA-Lu177 radioligand therapy. We introduce a hybrid (AI/semantic knowledge) segmentation pi...
Authors: Carl D. Elliston, Lawrence Koutcher, Michael J. Price, Adam C. Riegel, Michael B Sisti, Tony J.C. Wang, Andy (Yuanguang) Xu
Affiliation: Columbia University Irving Medical Center
Abstract Preview: Purpose: An inverse treatment planning software was recently introduced to Gamma Knife radiosurgery. The purpose of this study is to compare the plan quality of the Gamma Knife ”Lightning” with that o...
Authors: Reza Farjam, Russell K Hales, Todd R. McNutt, Mohammad Rezaee, Ehsan Tajikmansoury, K. Ranh Voong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Optimal beam angles and off-axis isocenter selection are important to achieve high quality plan and collision-free delivery in stereotactic body radiotherapy (SBRT) of the posteriorly located...
Authors: Hao Gao, Qiang Li, Yuting Lin, Wei Wang, Wei Wu, Weijie Zhang
Affiliation: Institute of Modern Physics, Chinese Academy of Sciences, China, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Carbon minibeam radiation therapy (cMBRT) offers high peak-to-valley dose ratio (PVDR) and relative biological effectiveness. A key challenge is balancing uniform target coverage with PVDR pr...
Authors: Lando S. Bosma, Victoria Brennan, Nicolas Cote, ChengCheng Gui, Nima Hassan Rezaeian, Jue Jiang, Sudharsan Madhavan, Josiah Simeth, Neelam Tyagi, Harini Veeraraghavan, Michael J Zelefsky
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, NYU Langone Health, University Medical Center Utrecht, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Deep learning-based deformable image registration (DIR) models often lack robustness when applied to datasets with differing imaging characteristics. We aimed to (1) improve registration netw...
Authors: Sameera Kumar, Chang Ming Charlie Ma, Robert A. Price
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose:
Difficulty assessing lung limits during treatment planning in the retreatment environment can be compounded as limits are volume-based (ie. VxGy<37%) and require a critical volume with a m...
Authors: Matthew Brown, Yushi Chang, Jinhyuk Choi, William Silva Mendes, Lei Ren, Aman Sangal, William Paul Segars, Phuoc Tran, Hualiang Zhong
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Digital phantoms like XCAT are essential for imaging and treatment optimization in radiology and radiation oncology. However, the lack of realistic textures (HU distribution) in XCAT limits i...
Authors: William G. Breen, Dalton Griner, Scott C Lester, Joseph John Lucido, Beth A. Schueler, Jack C. Thull
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Designing a total skin electron (TSE) beam therapy protocol requires finding the optimal balance between penetration depth, field uniformity, and x-ray contamination (XC). To better understan...
Authors: Izabella L. Barreto, Benjamin Taylor Heggie, Stephanie M. Leon
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: Filament deposition modeling (FDM) 3D printers may utilize proprietary calibration methods inadequate for medical imaging. Proper techniques are necessary to achieve imaging uniformity standa...
Authors: Wesley S. Culberson, Ryan Gardner, John Thomas Stasko
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, University of Wisconsin
Abstract Preview: Purpose: X-ray tube voltage is a critical parameter in influencing an X-ray tube’s beam quality. The endpoint tube potential, the potential difference between the X-ray tube’s cathode and anode, is pa...
Authors: Bryan Bednarz, Laura Bennett, Abby E. Besemer, Tyler J Bradshaw, Steve Y Cho, John M. Floberg, Joseph Grudzinski, Elissa Khoudary, Michael J. Lawless
Affiliation: Department of Radiology, University of Wisconsin, University of Wisconsin-Madison Department of Medical Physics, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Voximetry, Inc, University of Pennsylvania, Department of Radiology, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: To assess the impact of using a standardized immobilization setup for multi-time-point SPECT/CT imaging on radiopharmaceutical therapy (RPT) dosimetry image registration.
Methods: Ten ...
Authors: Karam Ayoub, Aaron B Hesselson, Ronald C McGarry, Joshua Misa, Damodar Pokhrel
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Department of Cardiology
Abstract Preview: Purpose: Noninvasive stereotactic body radiosurgery (SBRS) is emerging treatment option for advanced heart failure patients with refractory-ventricular tachycardia (rVT) who experienced recurrent impl...
Authors: Lori Buchholtz, Alison Garda, Chris L. Hallemeier, Kathryn L. Kolsky, Han Liu, Joseph John Lucido, Marisa Schinter, Andrew J. Veres, Sara Walerak
Affiliation: Mayo Clinic
Abstract Preview: Purpose: The C_START initiative aims to streamline and simplify the Direct-to-Unit (DtU) clinical setup and treatment planning process for photon radiation therapy, particularly for emergent cases suc...
Authors: Huixiao Chen, Zhe (Jay) Chen, MinYoung Lee, Sameer Taneja
Affiliation: Yale School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: Superficial radiation therapy uses low-energy x-rays to treat various types of cancers, including non-melanoma skin cancers, and dermatological conditions such as keloid scars, mycosis fungoi...
Authors: Caroline Cheney, Patricia G Collins, Allen R. Goode, Preston Le, Andrew M. Polemi, Angela Snyder
Affiliation: UVA Health, Atirix Medical Systems
Abstract Preview: Purpose: Optimize ongoing quality control (QC) for radiographic (DR) and fluoroscopic (FL) systems by identifying metrics most sensitive to hardware disruptions among regional noise, pooled noise, sig...
Authors: Ted Lynch
Affiliation: Sun Nuclear, a Mirion Medical Company
Abstract Preview: Purpose: A novel ultrasound quality assurance method is presented that constructs “synthetic spheres” at arbitrary locations within the image frame by combining correlation length measurements from a ...
Authors: Avery Antes, Bulent Aydogan, Rama Chicfeh, Erik Pearson, Neslihan Sarigul
Affiliation: The University Of Chicago, The University of Chicago
Abstract Preview: Purpose: This study evaluates the performance of the Ethos Treatment Planning System (TPS) in managing oligometastatic cancer patients previously treated using multiple isocenter plans.
Methods: Th...
Authors: Gong Vincent Hao, Daisuke Kawahara, Jokichi Kawazoe, Yuji Murakami, Ikuno Nishibuchi, Peiying Colleen Ruan, Daguang Xu, Dong Yang
Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University, NVIDIA
Abstract Preview: Purpose:
Accurate tumor segmentation in head and neck cancer is critical for effective treatment planning, but variability in practices across medical facilities poses challenges for standardizatio...
Authors: David L. Barbee, Jose R. Teruel Antolin, Jinyu Xue
Affiliation: NYU Langone Health
Abstract Preview: Purpose: This work introduces a method of regional dose evaluation of normal brain tissue using local target-specific evaluation and compares to global dose evaluation for linac-based single-isocenter...
Authors: Azza Mohamed Ahmed, Nadine Francis, Osama Khan, Nabil Maalej, Aamir Raja, Briya Tariq
Affiliation: Khalifa University
Abstract Preview: Purpose: The study aims to evaluate the task-specific diagnostic performance of spectral photon-counting CT (SPCCT) using application-specific phantoms.
Methods:
Parameters such as linearity res...
Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu
Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center
Abstract Preview: Purpose: To determine the system parameters and technique factors for image acquisition needed so that the mean glandular dose (MGD) of approximately 4.5 mGy is not exceeded for a recently developed, ...
Authors: Lawrence T. Dauer, Yusuf Emre Erdi, Yiming Gao, Dustin W. Lynch, Usman Mahmood
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Radiation dose to patients in CT examinations (CTDIvol, DLP) is tracked in dose monitoring solutions. Some solutions push for automatically estimating patient organ doses based on exam images...
Authors: Joana Antunes, Scott James Bright, David B. Flint, Mojtaba Hoseini-Ghahfarokhi, Mandira Manandhar, Poliana Marinello, Gabriel O. Sawakuchi, Tingshi Su
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Laboratory of Instrumentation and Experimental Particle Physics; Faculty of Science of University of Lisbon, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, MD Anderson Cancer Center
Abstract Preview: Purpose: To study the accuracy of relative biological effectiveness (RBE) models to predict the RBE of a comprehensive panel of pancreatic cancer cell lines.
Methods: Clonogenic cell survival w...
Authors: Yizheng Chen, Michael Gensheimer, Mingjie Li, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose: Automatically translating non-contrast to contrast-enhanced computed tomography (CT) images is critical for improving clinical workflow, reducing heathcare cost, minimizing radiation exposure...
Authors: Janet Ching-Mei Feng, Jimmy Huynh
Affiliation: UTHealth McGovern Medical School
Abstract Preview: Purpose: The Image Gently Alliance had provided helpful information to optimize image protocols in pediatric patients since 2007, and our assumption was that newer units could use near-to-optimal prot...
Authors: Anthony R Bardwell, Dong Won Kim, Faith S Kim, Isaac Y Kim, Juying Zhang
Affiliation: Kaiser Permanente
Abstract Preview: Purpose: When a patient develops a significant skin reaction at some point during postmastectomy radiotherapy, a clinical decision is often made to discontinue the planned daily use of bolus. The aim ...
Authors: Jenghwa Chang, Chingyun Cheng, J Isabelle Choi, Muhammad Hamza, Minglei Kang, Tyler Kaulfers, Grant Lattery, Haibo Lin, Charles B. Simone, Xingyi Zhao
Affiliation: Peking University, Hofstra University Medical Physics Program, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Physics and Astronomy, Hofstra University, Physics Resident at Montefiore Einstein, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: In terms of high dose rate FLASH, the question remains on how to properly deliver treatment and what clinical sites are feasible to deliver such treatment. The novel Bragg peak (BP-FLASH) and...
Authors: Daniela Branco, John M Bryant, Shalom Kpetsu, Ann T. Nguyen, Gage H. Redler, Peter Allan Sandwall, Eman Suliman, Charles R. Thomas, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, University of South Florida Morsani College of Medicine, Alzahraa University Hospital, Dartmouth College, Moffitt Cancer Center, OhioHealth, Purdue University, University of California San Diego / California Protons, Department of Radiation Oncology, Moffitt Cancer Center
Abstract Preview: Purpose: Access to radiological health services in sub-Saharan Africa (sSA) remains extremely inadequate, with over 90% of the population in most countries lacking access to radiotherapy and facing si...
Authors: Chia-Lung Chien, Renteng Hou, Wen C. Hsi, Faraz Kalantari, Ganesh Narayanasamy, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose:
PRDR is an effective re-irradiation treatment for patients who have already reached the tolerance dose to their organs at risk (OARs). While PRDR is implemented on TrueBeam by limiting the...
Authors: Jiayun Chen, Shengqi Chen, Junchao Li, Fei Liu, Jianan Wu
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, Tongji Medical College, Huazhong University of Science & Technology, School of Electronic Engineering, Beijing University of Posts and Telecommunications, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: To assess if 3D Vane MRI can accurately depict the motion of the target volume and OARs.
Methods: This retrospective study included 54 liver cancer patients who underwent both 3D Vane MRI ...
Authors: Sara Allievi, Stefano Bonvini, Gloria Miori, Laura Orsingher, Andrea Passerini, Igor Raunig, Daniele Ravanelli, Erich Robbi, Annalisa Trianni
Affiliation: Department of Information Engineering and Computer Science, University of Trento, Vascular Surgery Department, S.Chiara Hospital, APSS, Medical Physics Department, S.Chiara Hospital, APSS
Abstract Preview: Purpose:
This study evaluates the performance of an AI-driven tool in segmenting and analyzing tissue composition in abdominal aortic aneurysm (AAA) patients, specifically focusing on the sealing z...
Authors: Ross Bland, Zachary A. Christ, Sophy Mangana, Feba Mathew, Stephanie K. Phoenix, Joseph Salloum, Jason D. Stanford, William Zollinger
Affiliation: Forrest General Cancer Center, Northeast Louisiana Cancer Institute, Florida Atlantic University
Abstract Preview: Purpose: The objective of this paper is twofold: 1) to explore the efficacy of using referenced beam models supplied by the vendor (Brainlab) and 2) the efficacy of NIST traceable TLD for end-to-end v...
Authors: Frank F. Dong, Megan C. Jacobsen, Ke Li, Xinming Liu, Humberto Monsivais, John Rong
Affiliation: Purdue University, UT MD Anderson Cancer Center
Abstract Preview: Purpose: To investigate the noise characteristics of a clinical photon counting detector CT (PCD-CT) system along axial and through-plane (Z) dimensions using 3D NPS measurements.
Methods: This stu...
Authors: Hyosung Cho, Dae Yup Han, Duhee Jeon, Jiwon Park, Hyesun Yang
Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine, Yonsei University
Abstract Preview: Purpose: To precisely detect intrafraction patient motion during spine stereotactic body radiotherapy (SBRT) treatment delivery, we propose an optimized technique for three-dimensional reconstruction ...
Authors: Liang-Hsin Chen, Li-Chien Wei
Affiliation: National Taiwan University Cancer Center
Abstract Preview: Purpose: For proton therapy treatment, it is essential to ensure that the treatments are delivered safely and accurately. Quality assurance (QA) programs of proton treatment system is needed and proto...
Authors: Kevin Peter Risolo
Affiliation: University of Pennsylvania
Abstract Preview: Purpose: To quantify the improved efficiency of checking patient treatment plan MU by utilizing RadFormation’s ClearCalc script-based program.
Methods: A total of 58 patients planned for treatment ...
Authors: Xinhui Duan, Vivek Nair, Liqiang Ren, KyuHo Song, Kuan Zhang, Yue Zhang
Affiliation: Department of Radiology, UT Southwestern Medical Center
Abstract Preview: Purpose: To evaluate how tin-filtered spectral shaping in clinical photon-counting computed tomography (PCCT) affects noise magnitude across varying object sizes, radiation doses, and spectral reconst...
Authors: Liang-Hsin Chen, Hsiang-Kuang Tony Linag
Affiliation: National Taiwan University Cancer Center, Department of Biomedical Engineering, National Taiwan University
Abstract Preview: Purpose: The characteristics of scanning proton beam is one of crucial factors to affect dose delivering accuracy in proton theray. Therefore, this study aims to evaluate and monitor the stability of ...
Authors: Petr Bruza, Rafael Carballeira, Megan Clark, David J. Gladstone, Austin Sloop, Roman Vasyltsiv, Kevin Jacob Willy
Affiliation: Dartmouth College, Thayer School of Engineering, Dartmouth College
Abstract Preview: Purpose: Develop an optical dosimetry system to accomplish standard of care on-patient dosimetry and pretreatment quality assurance for ultra-high dose rate (UHDR) electron therapy ahead of human tria...
Authors: Petr Bruza, Yao Chen, David J. Gladstone, Lesley A Jarvis, Brian W Pogue, Kimberley S Samkoe, Yucheng Tang, Shiru Wang, Rongxiao Zhang
Affiliation: NVIDIA Corp, Dartmouth College, Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, University of Missouri, University of Wisconsin - Madison
Abstract Preview: Purpose: Cherenkov imaging provides real-time visualization of megavoltage radiation beam delivery during radiotherapy. Patient-specific bio-morphological features, such as vasculature, captured in th...
Authors: Jing Qian, Brandon Reber, David M. Routman, Satomi Shiraishi
Affiliation: Mayo Clinic
Abstract Preview: Purpose: The dose distribution in proton radiotherapy (PRT) is characterized by sharp gradients, posing a challenge for machine learning-based dose prediction. While denoising with diffusion processes...
Authors: Rebecca Lamoureux, Zahra (Zara) Razi, Zachary Whipps
Affiliation: University of New Mexico Hospital
Abstract Preview: Purpose: Patient mispositioning in CT imaging contributes to inconsistent radiation dose delivery and suboptimal image quality, impacting patient safety and diagnostic outcomes. This study evaluates a...
Authors: Jenny Dankelman, Ben J. M. Heijmen, Inger-Karine K. Kolkman-Deurloo, Remi A. Nout, Linda Rossi, Robin Straathof, Linda Wauben, Henrike Westerveld, Nick J. van De Berg, Sharline M. van Vliet - Perez
Affiliation: Department of BioMechanical Engineering, Delft University of Technology, Department of Gynecological Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam
Abstract Preview: Purpose:
To quantify the dosimetric advantages of the 3D-printed patient-tailored ARCHITECT applicator with optimized needle channel configurations compared to clinically used intracavitary/interst...
Authors: John T Barrett, Dan Heo, Chulhaeng Huh, Farshad Mostafaei
Affiliation: Department of Radiation Oncology, Medical College of Georgia, Augusta University, Department of Radiation Oncology, Augusta University
Abstract Preview: Purpose: This study aimed to compare the tumor control probability (TCP) of radiation therapy (RT) and magnetic hyperthermia combined with RT (MHRT) in the human prostate cancer cells based on radiobi...
Authors: Lili Chen, Dusica Cvetkovic, Chang Ming Charlie Ma, Dae-Myoung Yang
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Cytotoxicity caused by the reactive oxygen species (ROS) is a mechanism for treating cancer cells in radiation therapy. 5-aminolevulinic acid (5-ALA)-mediated radiodynamic therapy (RDT), whic...
Authors: Stephen R. Bowen, Shijun Chen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Qianqian Tong, Jiajie Wang, Shouyi Wang, Faisal Yaseen
Affiliation: The University of Texas at Austin, Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Fred Hutchinson Cancer Center, University of Texas at Arlington
Abstract Preview: Purpose: Tumor subregion clustering and prediction of region-specific response can augment assessments and adaptive treatment decisions. A modeling framework was constructed to predict chemoradiation ...
Authors: Lu Jiang, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Conventional radiotherapy treatment planning is guided by a set of generic objectives that are unspecific to patient anatomy. Treatment planning thus heavily relies on the planner’s experi...
Authors: Guangjun Li, Ying Song, Huanan Tang, Tianxiong Wu, Qiuyi Ye, Wei Zhang
Affiliation: West China Second Hospital of Sichuan University, United Imaging Healthcare, West China Hospital of Sichuan University
Abstract Preview: Purpose:
To propose a general low-dose reconstruction model for ultra-sparse-view cone-beam CT (CBCT) and evaluate its clinical application in improving image quality and reducing radiation dose fo...
Authors: Fred B. Bateman, Ilaria M. Luna, Ronald E. Tosh
Affiliation: Sidwell Friends School, NIST, Dosimetry Group, Radiation Physics Division, National Institute of Standards and Technology
Abstract Preview: Purpose: To exploit the rapid response time and dose sensitivity of ultrasonic detection methods for resolving pulse structure in FLASH-level beams.
Methods: Two ultrasonic transducers position...
Authors: Shifeng Chen, Yannick P. Poirier, Huijun Xu, Byong Yong Yi, Baoshe Zhang, Hong Zhang, Jinghao Zhou
Affiliation: University of Maryland School of Medicine, University of Maryland Shore Regional Cancer Center, Vanderbilt University Medical Center, Department of Radiation Oncology, University of Maryland School of Medicine, Capital Region Medical Center
Abstract Preview: Purpose: To thoroughly assess the resilience of HyperArc VMAT plans for multiple brain metastases (MBT) in relation to (i) high-definition MLC leaf positional inaccuracies and (ii) patient rotational ...
Authors: Amy Berrington de Gonzalez, David Borrego, Rochelle Curtis, Gretchen L Gierach, Jae Won Jung, Choonik Lee, Choonsik Lee, Matthew Mille, Lene Veiga, Jacqueline Vo
Affiliation: University of Michigan, East Carolina University, Radiation Protection Division, Office of Radiation and Indoor Air, U.S. Environmental Protection Agency, National Cancer Institute, Institute of Cancer Research
Abstract Preview: Purpose: Radiotherapy is vital for treating breast cancer, but its long-term health effects remain a concern. Accurate dose reconstruction is crucial for evaluating risks in retrospective epidemiologi...
Authors: Yunxiang Li, Weiguo Lu, Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Curating high-quality, labeled data for medical image segmentation can be challenging and costly, considering the existence of various image domains with differing modalities/protocols. Cr...
Authors: Eric S. Diffenderfer, Lei Dong, Alejandro Garcia, Wenbo Gu, Michele M. Kim, Alexander Lin, Kai Mei, Peter B. Noël, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: We present a novel 3D-printed range-modulating devices with spatially modulated density for FLASH particle therapy. By varying density distributions, spread-out Bragg peaks(SOBPs) can be gene...
Authors: Muhammad Ramish Ashraf, Kerriann Casey, Suparna Dutt, Jie Fu, Edward Elliot Graves, Xuejun Gu, Hao Jiang, Brianna Caroline Lau, Billy W Loo, Weiguo Lu, Rakesh Manjappa, Stavros Melemenidis, Erinn Bruno Rankin, Lawrie Skinner, Luis Armando Soto, Murat Surucu, Vignesh Viswanathan, Zi Yang, Amy Shu-Jung Yu
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine, Department of Comparative Medicine, Stanford University School of Medicine, Department of Radiation Oncology, Stanford University Cancer Center
Abstract Preview: Purpose: The intestine is a classical preclinical model for studying radiation injury, and histological quantification of intestinal crypts is a key assay for assessing this response. However, substan...
Authors: Ming Dong, Carri K. Glide-Hurst, Behzad Hejrati, Joshua Pan, Yuhao Yan
Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Upright patient positioners and vertical CT reduce tumor motion and stabilize internal anatomy during treatment delivery. Yet, to fully exploit the advantages of upright, translation of stand...
Authors: Shira Abraham, Eric Aliotta, Michalis Aristophanous, Laura I. Cervino, Yu-Chi Hu, Phillip G. Lichtenwalner, Chuan Zeng, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
We have developed a tool that uses deformable image registrations to perform deformable dose accumulation. In this work we evaluate use of this tool for adaptive head and neck dose accumul...
Authors: Hulya Ozdemir Buss, Julius G. Ojwang, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: The CyberKnife (CK) Synchrony system provides sub-millimeter motion-tracking accuracy during stereotactic body radiotherapy (SBRT). For lung tumors near the diaphragm, we evaluated the feasib...
Authors: Minsong Cao, Amar Kishan, Dylan P. O'Connell, Jonathan Pham, Michael Steinberg, Luca F Valle, Michael Xiang
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: To evaluate bladder ultrasound as a surrogate for estimating on-table bladder volume in prostate cancer patients undergoing stereotactic body radiation therapy (SBRT). The study aimed to asse...
Authors: Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, Tae Ho Kim, Sangmin Lee
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: The CyberKnife system, designed for stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), considers SRS MapCHECK an effective tool for patient-specific QA (PSQA). This wo...
Authors: Dong Wook Kim, Jin Sung Kim, Dongho Lee, Sangmin Lee
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Seoul, Korea, Republic of (South)
Abstract Preview: Purpose:
This study aims to analyze the characteristics of a novel detector based on a dielectric layer (Vieworks Co., Korea), which demonstrates high tolerance to high radiation doses and light tr...
Authors: Farhad Jafari, Brandon Hai Nguyen
Affiliation: Department of Radiation Oncology, University of Minnesota Medical School, Department of Radiology, University of Minnesota
Abstract Preview: Purpose: To validate a bottom-up approach to dosimetry in nuclear medicine.
Methods: A pharmacokinetic model is developed to represent the flow of activity between different compartments of the...
Authors: Cambridge L Bui-Nguyen, Alexander S. Nguyen, Liqiang (Lee) Tao
Affiliation: Varian AOS @Epic Care, UC Berkeley
Abstract Preview: Purpose: To quantity variations in Winston Lutz (WL) test results due to different energies used in SBRT, SRT or SRS.
Methods: A WL phantom with a 6.4 mm diameter center radio-opaque sphere is used...
Authors: Laura I. Cervino, Linda X. Hong, Jessica Pagan, Angelica A. Perez-Andujar, Maria Thor
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Memorial Sloan-Kettering Cancer Center
Abstract Preview: Purpose: Three-dimensional conformal radiotherapy (3DCRT) and Volumetric-Modulated Arc Therapy (VMAT) are used to treat locally advanced breast cancer. The 3DCRT treatment plans use the treatment fiel...
Authors: Michael Baine, Yang Lei, Yu Lei, Ruirui Liu, Tian Liu, Jing Wang
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center
Abstract Preview: Purpose: Accurate 3D deformable registration of MRI and ultrasound (US) is essential for real-time image guidance during high-dose-rate (HDR) prostate brachytherapy. However, MRI-US registration of th...