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Results for "Catherine Coolens": 3 found

Investigating Interstitial Fluid Pressure and Hydraulic Conductivity By Examining the Biophysical Properties of Drug Transport Using Cross Voxel Exchange Model and Dynamic Contrast Enhanced MRI

Authors: Catherine Coolens, Janny Yeyoung Kim, Michael Milosevic, Noha Sinno

Affiliation: Princess Margaret Hospital, University of Toronto

Abstract Preview: Purpose: In solid tumors, Interstitial fluid pressure (IFP) acts as a barrier to molecular transport to the tumor center and serves as a predictor of cancer patients’ treatment responsiveness. The nov...

Monte Carlo Derived Correction Factors for Ion Chambers Used in the Calibration of Gamma Knife Perfexion Model: Impact of Phantom Materials and Chamber Orientation on Dosimetric Accuracy

Authors: Catherine Coolens, Robert K. Heaton, Lalageh Mirzakhanian, Tasnim Rahman, Jan P. Seuntjens

Affiliation: Princess Margaret Cancer Centre & University of Toronto, McGill University, Princess Margaret Cancer Centre, Princess Margaret Hospital, University of Toronto

Abstract Preview: Purpose: Commissioning of a Gamma Knife® (GK) (Elekta, Sweden) unit requires precise dosimetric reference measurements, particularly for small fields. The IAEA TRS-483/AAPM TG-155 code of practice (20...

Validation of an Ivim Tool for Liver Hypoxia Assessment for an Online Adaptive MR-Linac System

Authors: Jean-Pierre Bissonnette, Catherine Coolens, Laura Dawson, Ryan A Kuhn, Michael Maddalena, Teo Stanescu

Affiliation: Princess Margaret Hospital, The Princess Margaret Cancer Centre - UHN, University of Toronto, Princess Margaret Cancer Centre

Abstract Preview: Purpose: To investigate the generation and reproducibility of 3D hypoxia maps in liver hepatocellular carcinoma (HCC) patients using data derived from an Intravoxel Incoherent Motion (IVIM) MR sequenc...