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Results for "William Jeck": 16 found

A Topological Technique to Unify Image Texture and Morphology to Enhance Radiomic Feature Representations

Authors: David Brizel, Kyle J. Lafata, Jian-Guo Liu, Yvonne M Mowery, Yvonne M Mowery, William Paul Segars, Jack B Stevens

Affiliation: Department of Physics, Duke University, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh

Abstract Preview: Purpose: To develop a technique to quantify tumor topology using a unifying mathematical framework that integrates texture and morphology and to evaluate its feasibility as a prognostic biomarker for ...

Automated Treatment Planning for Stereotactic Recurrent Head and Neck Cancers Using Knowledge-Based Planning, Multicriteria Optimization, and Dosimetric Scorecards

Authors: Shane McCarthy, Damodar Pokhrel, William St. Clair, Eddy S Yang

Affiliation: University of Kentucky, Department of Radiation Medicine

Abstract Preview: Purpose: Demonstration of automated stereotactic treatment planning for recurrent head and neck (RHN) cancers using knowledge-based planning, multicriteria optimization (MCO), and dosimetric scorecard...

Clinical Validation of a Deep-Learning Segmentation Tool for Head and Neck Cancer Patients and Thoracic and Abdominal Cancer Patients

Authors: Haijian Chen, Katja M. Langen, William Andrew LePain, Claire Tran, Mingyao Zhu

Affiliation: Emory Healthcare, Emory University, Georgia Institute of Technology

Abstract Preview: Purpose: To validate the performance of a commercial deep-learning segmentation (DLS) tool for head and neck cancer (HNC) and thoracic and abdominal cancer (TAC) by comparing it to manual segmentation...

Commission and Clinical Implementation of the 1st Step-and-Shoot Proton Arc Therapy for Head and Neck Cancer Patient Treatment

Authors: Xiaoda Cong, Rohan Deraniyagala, Xuanfeng Ding, Xiaoqiang Li, Jian Liang, Peilin Liu, Craig Stevens, Xiangkun Xu, Weili Zheng

Affiliation: Corewell Health William Beaumont University Hospital, Corewellhealth William Beaumont University Hospital, William Beaumont University Hospital, Corewellhealth William Beaumont Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital

Abstract Preview: Purpose:
Commission a step-and-shoot arc therapy(SPArc-step&shoot) for treating head-neck cancer patients as a desired interim milestone toward full dynamic treatment.
Methods:
An in-house de...

Development of a Quantitative Surface Mapping Analysis Framework Involving a Robust Mask Removal Algorithm for Improved Objective Patient Setup Assessment in Head and Neck Intensity Modulated Proton Therapy

Authors: Grant Evans, Maxwell Arthur Kassel, Charles Shang, Michael H. Shang, Stephen Shang, Timothy R Williams

Affiliation: South Florida Proton Therapy Institute, SFPRF, Department of Radiation Medicine, MedStar Georgetown University Hospital

Abstract Preview: Purpose:
Daily image guidance for head and neck intensity-modulated proton therapy (IMPT) presents significant challenges due to large target volumes and anatomical changes. Geometric deviations al...

Dosimetric Parameter Cross-Check Evaluations for Dedicated Biologically-Guided Radiotherapy Linac Using Two Water Phantom Systems

Authors: Nguyen Phuong Dang, Mason Hazlett, Lijun Ma, Yutaka Natsuaki, William T. Watkins, Zhengzheng Xu, Timothy Pok Chi Yeung

Affiliation: Reflexion Medical Inc,, Radiation Oncology, Keck School of Medicine of USC, RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center

Abstract Preview: Purpose: This is the first study reporting the beam dosimetric parameter cross-checks of Reflexion linac using different water phantom systems and detectors. The difference in measurements using diffe...

Ensuring Consistency in Digital Pathology: Medical Physics Approaches to Comparison of Scanner Contrast and Chromaticity

Authors: Diana Cardona, Casey C. Heirman, William Jeck, Kyle J. Lafata, Xiang Li, Lauren M. Neldner, Jeffrey S. Nelson, Megan K. Russ, Ehsan Samei

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Pathology, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Medical physicists have traditionally supported radiation-based medicine, but their expertise can translate to other image-based fields including pathology. As pathology transitions to digita...

Ensuring Consistency in Digital Pathology: Medical Physics Approaches to Comparison of Scanner Sharpness and Artifact Severity

Authors: Diana Cardona, Casey C. Heirman, William Jeck, Kyle J. Lafata, Xiang Li, Lauren M. Neldner, Jeffrey S. Nelson, Megan K. Russ, Ehsan Samei

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Pathology, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Medical physicists traditionally support radiation-based medicine, but their expertise is translatable to image-based fields like pathology. As pathology transitions to digital practices, phy...

Evaluation of Color Display Performance of Pathology Relevant Colors Using the Macbeth Colorchecker

Authors: Diana Cardona, Casey C. Heirman, William Jeck, Kyle J. Lafata, Lauren M. Neldner, Jeffrey S. Nelson, Megan K. Russ, Ehsan Samei

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Pathology, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Display image accuracy is critical for digital diagnostic fields, such as radiology and digital pathology. While the AAPM TG-18 test patterns are established for grayscale radiology monitor Q...

JACK KROHMER EARLY-CAREER INVESTIGATOR COMPETITION WINNER: Direct Measurement of an Early Change in Tumor Oxygenation in Response to Radiation with Oxygen Enhanced Electron Paramagnetic Resonance Imaging (OE-EPRI)

Authors: Jorge De La Cerda, Andrew Joseph Fanning, Tianzhe Li, Xiaofei Liang, Grace Murley, Mark Pagel, William Schuler, Renee Tran, Shuo Wang, Su-Min Zhou

Affiliation: University of Wisconsin Madison, University of Nebraska Medical Center, University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Electron paramagnetic resonance imaging (EPRI) can be used to image partial pressure of oxygen (pO2) in tumor models. The goal of this study is to develop an Oxygen Enhanced EPRI protocol to ...

Knowledge-Informed Deep Learning for Accurate and Interpretable Extracapsular Extension Detection in Head and Neck Squamous Cell Carcinoma

Authors: William N. Duggar, Amirhossein Eskorouchi, Haifeng Wang

Affiliation: Mississippi State University, University of Mississippi Medical Center

Abstract Preview: Purpose:
Extracapsular extension (ECE) in lymph nodes represents a critical prognostic factor in head and neck squamous cell carcinoma (HNSCC), bearing important implications for staging, treatment...

Personalized and Automated Head & Neck Radiotherapy Planning with AI-Guided Optimization

Authors: Michael Bowers, Patrik Brodin, Madhur Garg, Rafi Kabarriti, William P. Martin, Todd R. McNutt, Julie Shade, Wolfgang A. TomΓ©, Christian Velten

Affiliation: Johns Hopkins University, Oncospace, Inc., Montefiore Medical Center

Abstract Preview: Purpose: Development of an automated planning tool utilizing AI generated patient-specific dose-volume histogram predictions for rapid H&N plan generation.
Methods: Planning best-practices were dev...

Phantom-Based Dosimetric Comparison of Multiple CT Metal Artifact Reduction Algorithms for Head-and-Neck Radiotherapy

Authors: Loren Bell, Charles S Cathcart, Brett William Eckroate, Harold Y Hu, Joshua Kilian-Meneghin, Ke Nie, Fredrick Warburton, Zhenyu Xiong, Keying (Karen) Xu, Ning J. Yue, Yin Zhang, Lili Zhou

Affiliation: RWJBarnabas Health, Basis Scottsdale, Rutgers Cancer Institute of New Jersey

Abstract Preview: Purpose: This study compares the dosimetric impact of multiple metal artifact reduction (MAR) algorithms from different CT simulator vendors using an anthropomorphic head phantom for head-and-neck (H/...

Robust and Radiobiologically Accurate Dose Summation Strategy for Multiple Courses of Stereotactic Re-Irradiation of Metastatic Brain Cancer Patients with Previous WBRT

Authors: Garrett Russell Hamilton, Joshua Misa, Damodar Pokhrel, William St. Clair

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine

Abstract Preview: Purpose: Recurrent brain metastasis is very common, and patients who previously received whole-brain radiotherapy (WBRT) may receive an additional course(s) of stereotactic radiosurgery (SRS) to selec...

Spatial Variation and Dosimetry of X-Ray Contamination in Total Skin Electron Beam Therapy

Authors: William G. Breen, Dalton Griner, Scott C Lester, Joseph John Lucido, Beth A. Schueler, Jack C. Thull

Affiliation: Mayo Clinic

Abstract Preview: Purpose: Designing a total skin electron (TSE) beam therapy protocol requires finding the optimal balance between penetration depth, field uniformity, and x-ray contamination (XC). To better understan...

Tumor Dose Escalation for Recurrent Head and Neck SRT Via a Hyperarc-Based Rapidplan Model

Authors: Shane McCarthy, Damodar Pokhrel, William St. Clair, Eddy S Yang

Affiliation: University of Kentucky, Department of Radiation Medicine

Abstract Preview: Purpose: Demonstrating the feasibility of dose escalation for stereotactic recurrent head and neck (RHN) cancers through the deployment of a Hyper-Arc Based RapidPlan (HARP) model through an Eclipse S...