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Results for "accurate calculation": 67 found

A Foundational Model for Medical Imaging Modality Translation in Head and Neck Radiotherapy

Authors: Jie Deng, Yunxiang Li, Xiao Liang, Weiguo Lu, Jiacheng Xie, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Recently, foundational models trained on large datasets have shown remarkable performance across various tasks. Developing a foundational model for medical image modality translation in head-...

A GPU Accelerated Monte Carlo Dose Engine for Small Animal Proton Radiotherapy

Authors: Haonian Gong, Yue Gu, Meiqi Liu, Zihao Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang, Cheng Zheng

Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China

Abstract Preview: Purpose:
Proton radiotherapy in preclinical small animals requires specific dose engine due to its low energy and small irradiation volume. This study is to develop a GPU-based Monte Carlo dose eng...

A Monte Carlo Framework for Automated Quality Assurance of Dynamically Collimated Pencil Beam Scanning Clinical Treatment Deliveries

Authors: Laura Bennett, Wesley S. Culberson, Albert Du, Kevin J. Erhart, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake

Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care, .decimal

Abstract Preview: Purpose: To develop and experimentally validate a novel Monte Carlo (MC) framework designed to enable calculation-based quality assurance (QA) for collimated intensity modulated proton therapy treatme...

A Monte Carlo-Based Secondary Dose Verification Tool for Treatment Plans of Robotic Radiosurgery System

Authors: Chuxiong Ding, Xuejun Gu, Heejung Kim, Weiguo Lu, Yang Kyun Park, Yulong Yan

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: The purpose of this study was to develop and evaluate a Monte Carlo (MC) dose calculation software (DosemanCK) for secondary dose verification of CyberKnife (CK) treatment plans. Unlike tradi...

A Novel Multi-Material Decomposition Algorithm for Improved Material Quantification Using Dual-Energy CT

Authors: Dale Black, David Clymer, Huanjun Ding, Hamidreza Khodajou Chokami, Sabee Molloi, Christine Vy Nguyen, Tim Sananikone, Alireza Shojazadeh, Randy Wang

Affiliation: Department of Radiological Sciences, University of California, University of California, Department of Radiological Sciences, University of California, Irvine, Department of Radiological Sciences, University of California, Irvine

Abstract Preview: Purpose: We present a novel multi-material decomposition (MMD) algorithm for accurate quantification of material concentration in reconstructed dual-energy CT images. This method addresses limitations...

A Novel Semi-Analytic Approach for Dose Calculation in Proton Minibeam Radiotherapy

Authors: Hao Gao, Wangyao Li, Yuting Lin, Chao Wang, Wei Wu

Affiliation: Institute of Modern Physics, Chinese Academy of Sciences, Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: Proton minibeam radiation therapy (pMBRT) delivers a unique peak-and-valley dose pattern using collimators with narrow slits, offering improved normal tissue sparing compared to conventional ...

AI-Assisted Algorithm to Generate Patient Postures for Tset Dose Evaluation

Authors: Kostas Danniidis, Agelos Kratimenos, Yufu Wang, Timothy C. Zhu, Yifeng Zhu

Affiliation: University of Pennsylvania

Abstract Preview: Purpose: This study aims to develop software and algorithms utilizing artificial intelligence (AI) to seamlessly create 3D patient postures during Total Skin Electron Therapy (TSET). The resulting mes...

Addressing Radionuclide Decay Complexities in Targeted Alpha Therapy: A Computational Approach.

Authors: Denis Bergeron, Ryan P Fitzgerald, Ravneet Kaur, Rao Khan

Affiliation: John Hopkins University, NIST Radiation Physics Division, Howard University, National Institute of Standards and Technology

Abstract Preview: Purpose: There is growing interest in short-lived alpha-emitting radionuclides for cancer therapy due to their ability to selectively target and destroy cancer cells while sparing healthy tissue. Howe...

Advancing Thoracic Synthetic CT Images with Enhanced Cyclegan for Adaptive Radiotherapy Applications

Authors: Silambarasan Anbumani, Nicolette O'Connell, Eenas A. Omari, Amanda Pan, Eric S. Paulson, Lindsay Puckett, Monica E. Shukla, Dan Thill, Jiaofeng Xu

Affiliation: Elekta Inc, Elekta Limited, Linac House, Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Accurate electron density information from on-board imaging is essential for direct dose calculations in adaptive radiotherapy (ART). This study evaluates a deep learning model for thoracic s...

An Accelerated Scatter Estimation for Spectral CBCT Based on Linear Boltzmann Transport Equation

Authors: Zhiqiang Chen, Hewei Gao, Li Zhang, Guoxi Zhu

Affiliation: Tsinghua University

Abstract Preview: Purpose: Spectral cone-beam CT has better performance in material identification and quantitative analysis compared to single-energy cone-beam CT. However, X-ray scattering introduces significant scat...

An Analytical Approach to Monitor Unit Calculation in Extended Distance Total Body Irradiation (TBI)

Authors: Cheewai Cheng, Indra J. Das, Jeffrey Yui Hei Wong, Poonam Yadav

Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine

Abstract Preview: Purpose: Radiation treatment machine replacement brings chaos and urgency of timely completion of machine commissioning for every procedure used including TBI that are time consuming. Based on past ex...

An Educational Tool for Structural Shielding Design of X-Ray Facilities Using Open-Source Computer Graphics and Animation Software

Authors: Michael B. Altman, Zhuo Chen, Ella Lawrence, Borna Maraghechi, Ziad H. Saleh

Affiliation: Washington University School of Medicine, WashU Medicine

Abstract Preview: Purpose: Structural shielding design for x-ray facilities, as specified in NCRP Report No. 151, is a detailed process but an important component of Medical Physics graduate and post-graduate education...

An Integrated, Web-Based Tool for Automated Treatment Time Calculations, Data Visualization, and Documentation for Superficial Radiotherapy Using an SRT-100 Vision

Authors: Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Yongsook C. Lee, Michael Leyva, Alejandro Rene Llanes Lopez, Carlos M. Rivera, Ranjini P. Tolakanahalli

Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute, Miami Cancer Institute, Baptist Health

Abstract Preview: Purpose: Accurate treatment time calculation is a critical component of superficial radiotherapy (SRT), particularly for the SRT-100 Vision, where dose delivery depends on applicator geometry, treatme...

Assessing Dose Calculation Accuracy in Proton Plans Using Pin Ridge Filters

Authors: Zachary M. Diamond, Pretesh Patel, Sibo Tian, Yinan Wang, Xiaofeng Yang, David Yu, Ahmal Jawad Zafar, Jun Zhou

Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: High spatial resolution in pin ridge filter (pRF)-based proton planning may be constrained by the 1mm dose grid resolution in commercial treatment planning systems. This study investigates th...

Automated Quantitative Method for Source Position Calculation in Annual Quality Assurance of High Dose Rate Brachytherapy Gynecological Applicators

Authors: Ivan M. Buzurovic, Matthew W. Jacobson, Marjan Khosravi

Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, University of Massachusetts Lowell, Department of Physics, Lowell, MA/Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology

Abstract Preview: Purpose: Annual quality assurance (QA) of high dose rate (HDR) brachytherapy (BT) gynecological (GYN) applicators is critical to ensure accurate and consistent source position and dose delivery. In th...

Biomechanically Informed Diagnostic-to-Synthetic CT Transformation for Expedited Radiation Therapy Planning

Authors: Liyuan Chen, Steve Jiang, Chenyang Shen

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center

Abstract Preview: Purpose: Delays in radiation therapy (RT) initiation caused by conventional CT simulation processes can hinder timely treatment delivery and patient outcomes. This study proposes a Virtual Treatment S...

Brachyplancheck: An Independent Monte Carlo Dose Calculation Tool for Brachytherapy Using Egs_Brachy

Authors: Amy Tien Yee Chang, Chi Wai Cheung, Tin Lok Chiu, Chen-Yu Huang, Chi Wa Kong, Pei-Xiong Li, Pak Hang Nam, Bin Yang, Siu Ki Yu

Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital

Abstract Preview: Purpose: This study introduces BrachyPlanCheck, an independent Monte Carlo (MC)-based dose calculation tool for 192Ir brachytherapy retrospective study or algorithm commissioning.
Methods: BrachyPl...

Clinical Experience with an Independent Dose Calculation Software for ZAP-X Stereotactic Radiosurgery

Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang

Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center

Abstract Preview: Purpose: ZapMU is the first independent monitor unit check software freely available supporting ZAP-X. In this study, the clinical experience with ZapMU for independent second check of dose calculatio...

Commissioning of Elekta Leipzig and Valencia Skin Applicators

Authors: Hamid Aghdam, DJ Chen, Heather Chen, Sharad Goyal, Yonas Solomon Mekuria, Martin Ojong-Ntui, Yuan James Rao

Affiliation: The George Washington University, The George Washington University Cancer Center

Abstract Preview: Purpose: Elekta Leipzig and Valencia Skin applicators are designed to treat skin lesions. The applicators limit the irradiation to the required treatment area using a densimet shielding. Valencia uses...

Computed Tomography Organ Dose Library Derived from Newly Developed Newborn-Infant-Toddler Computational Phantoms

Authors: Jared Baggett, Wesley E. Bolch, Lukas M. Carter, Robert Joseph Dawson, Laura Dinwiddie, Adam Leon Kesner, Cameron B. Kofler, Juan Camilo Ocampo Ramos, Yitian Wang, Stefan Wehmeier

Affiliation: University of Chicago, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, University of Florida, MD Anderson

Abstract Preview: Purpose: To develop a slice-specific computed tomography (CT) organ dose library using Monte Carlo radiation transport simulations on a newly created set of newborn, infant, and toddler computational ...

Determination of HU Override for Small Metal Implants in Proton Therapy

Authors: Matthew Stephen Andriotty, Taoran Cui, Harold Y Hu, Ke Nie, Tan Phan, Xiao Wang, Ning J. Yue, Chengzhu Zhang

Affiliation: Rutgers Cancer Institute of New Jersey, Basis Scottsdale

Abstract Preview: Purpose: Metallic implants are often non-isocentric, and their exact volumes/orientations/shapes are difficult to capture and contour accurately on CT images even if that information is known beforeha...

Development and Implementation of MRI-Only Simulation, Planning and Treatment Workflow for Pelvic Radiotherapy Using Synthetic CT on MR-Linac

Authors: Peter Balter, Elaine Eunnae Cha, Seungtaek Choi, Yao Ding, Eun Young Han, Yusung Kim, Rajat J. Kudchadker, Belinda Lee, Surendra Prajapati, Reza Reiazi, Ergys D. Subashi, Sarath Vijayan, Jinzhong Yang, Yao Zhao

Affiliation: The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: This study evaluates the feasibility of an MR-only simulation, planning, and treatment (MROSPT) workflow for pelvic cancer patients using synthetic CT generated from MRI data. By validating s...

Development of a GPU-Based Dose Calculation Engine for MRI-Guided Proton Therapy

Authors: Yaowen Cao, Haonian Gong, Yue Gu, Meiqi Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang, Xiaogang Yuan

Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China

Abstract Preview: Purpose: Magnetic resonance imaging (MRI)-guided proton therapy is an innovative technology that combines superior soft tissue imaging capabilities of MRI with the high dose conformity of proton thera...

Development of a Novel Deformable Pelvis Phantom to Support Upright Applications

Authors: Adam P. Berdusco, Matthew R. Ceelen, Renata Farrell, Carri K. Glide-Hurst, Will Martin, Charles F. Maysack-Landry, Morgan A. McGauley, James Rice, Jordan M. Slagowski, Yuhao Yan

Affiliation: Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Upright radiotherapy (RT) is now available although this novel vertical CT and positioner presents unique challenges for quality assurance and testing methodologies. We have designed and buil...

Development of a Proton CT System Based on 2D Scintillation Detection

Authors: Haonian Gong, Yue Gu, Meiqi Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang

Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China

Abstract Preview: Purpose: To develop a proton CT system using scintillator-based 2D dose distribution detection for accurate proton imaging.
Methods: The proposed proton CT system consists of a brass collimator wit...

Dose Evaluation of Multiple Gammatiles in Heterogeneous Brain Models Using Egs_Brachy

Authors: Fatemeh Akbari, Artemis Dalby, Nelson A. Miksys, Prarthana Pasricha, Rowan M. Thomson

Affiliation: Ackerman Cancer Center, Carleton University

Abstract Preview: Purpose: To investigate dose evaluations for GammaTile brachytherapy, a novel treatment for brain malignancies. The analysis focuses on the impact of tissue heterogeneities, including the presence of ...

Dosimetric Accuracy Evaluation of Brainlab Elements 4.0 Treatment Planning System

Authors: Bhuvaneswari Narayanan, Niko Papanikolaou, Daniel L. Saenz

Affiliation: UT Health San Antonio, University of Texas HSC San Antonio

Abstract Preview: Purpose: To evaluate dosimetric accuracy of Brainlab Elements (BLE) 4.0 treatment planning system (TPS) for linac based SRS and Spine SBRT treatment.
Methods: RT Safe cranial and thorax phantoms wi...

Dosimetric Validation and Algorithmic Limitations of Pencil Beam Scanning Proton Therapy for Thin Chest-Wall Treatments

Authors: J Isabelle Choi, Meng Wei Ho, Isabel Lin, Hang Qi, Qi Zeng, Ajay Zheng

Affiliation: New York Proton Center, Scarsdale High School

Abstract Preview: Purpose: Proton therapy is a promising treatment modality for breast cancer due to its unique dosimetric advantage. Accurate dose calculation is critical to ensure effective treatment outcomes. The fo...

Dual-Domain Neural Network Cone-Beam CT Correction for Online Adaptive Proton Therapy

Authors: Daniel H. Bushe, Arthur Lalonde, Hoyeon Lee, Harald Paganetti, Brian Winey

Affiliation: Universite de Montreal, Massachusetts General Hospital, Massachusetts General Hospital and Harvard Medical School, University of Hong Kong

Abstract Preview: Purpose: Improving the precision and fidelity of daily volumetric imaging is essential for enabling adaptive proton therapy (APT). While cone-beam CT (CBCT) provides daily volumetric imaging, their ut...

Enhanced Surface Dose Accuracy in Proton Treatment Planning: Optimizing External Volume HU Thresholding.

Authors: Michael Butkus, Camilo M. Correa Alfonso, Olga M. Dona Lemus, James Arthur Perez-Sanchez

Affiliation: University of Miami

Abstract Preview: Purpose: Accurate skin dose calculation is essential for treating superficial lesions such as those of the breast, chest wall, and scalp. Clinical treatment planning systems often rely on approximatio...

Evaluate a Deep-Learning Auto-Segmentation Software for Liver SIRT

Authors: Wookjin Choi, Jun Li

Affiliation: Thomas Jefferson University

Abstract Preview: Purpose: Resin Yttrium-90 (Y-90) selective internal radiation therapy (SIRT) is a radioembolization procedure which uses Y-90 microspheres to treat metastatic liver cancer. In the procedure, liver vol...

Evaluation of Deformable Image Registration Accuracy Used in MR-Only Ventilation Mapping

Authors: Fei Han, James M. Lamb, Michael Vincent Lauria, Daniel A. Low, Tessa Elizabeth Maurer, Danilo Maziero, Claudia R. Miller, Drew Moghanaki, Louise Naumann, Nicolas Viot

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Siemens Healthineers, UCLA, University of California Los Angeles

Abstract Preview: Purpose: Patients with lung disease outside radiotherapy are barred from high dose protocols used for motion modeling, but MRI could offer no-dose alternatives. Image-based ventilation is a promising ...

Evaluation of Four Different Dose Calculation Algorithms for Commissioning of a New Tyoe of Scanned Proton Therapy System

Authors: Nobukazu Fuwa, Masato Horita, Takahiro Kato, Ryo Tanokura, Yuki Tominaga

Affiliation: Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Central Japan International Medical Center, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University

Abstract Preview: Purpose:
We have installed a new type of scanned proton therapy system (Varian ProBeam 360°TM). This study aimed to evaluate the four different dose calculation algorithms.
Methods:
Sixteen b...

Evaluation of Thoracic Direct Dose Calculation Using Truebeam Linac with Hypersight Imaging CBCT Solution

Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Alex T. Price, Sagar Regmi, Atefeh Rezaei, Runyon C. Woods

Affiliation: University Hospitals Seidman Cancer Center

Abstract Preview: Purpose: To investigate the feasibility and accuracy of using a Hounsfield Unit(HU) calibrated cone-beam computed tomography(CBCT) for direct dose calculation in thoracic treatment settings. In combin...

Fast Synthetic-CT-Free Dose Calculation in MR Guided RT

Authors: Claus Belka, Stefanie Corradini, George Dedes, Nikolaos Delopoulos, Christopher Kurz, Guillaume Landry, Ahmad Neishabouri, Domagoj Radonic, Adrian Thummerer, Niklas Wahl, Fan Xiao

Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, LMU Munich, Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), National Center for Radiation Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO)

Abstract Preview: Purpose: In MR-guided online adaptive radiotherapy, MRI lacks tissue attenuation information necessary for accurate dose calculations. Instead of using deep learning methods to generate synthetic CT i...

Feasibility of Commercial Independent-Dose-Calculation for Pencil-Beam-Scanning Proton Therapy

Authors: Wen C. Hsi, Kayla Schneider

Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences

Abstract Preview: Purpose:
Measurement-based patient-specific quality-assurance (PSQA) conducted with a 2D dosimeter to verify delivered dose of each field over 3 measurement-depths is time-consuming with limited se...

Feasibility of Efficient Offline Adaptive Replanning with Hypersight High-Performance Cone-Beam CT on Truebeam for Pelvis RT

Authors: Jochen Cammin, Shifeng Chen, Arun Gopal, Kai Huang, Jason K Molitoris, Amit Sawant, Kai Wang

Affiliation: University of Maryland, Department of Radiation Oncology, University of Maryland School of Medicine, Maryland University Baltimore, Department of Radiation Oncology, University of Maryland Medical Center

Abstract Preview: Purpose: The HyperSight CBCT optional feature on Varian TrueBeam linacs offers a larger field-of-view, improved Hounsfield units (HU) accuracy, and overall improved image quality, including metal arti...

Feasibility of Using a Dynamic-Platform with High-Resolution Patient-Specific QA Device for Periodic and Patient-Specific-QA in Respiratory-Gated Radiotherapy Lung SBRT Treatment

Authors: Tae Kyu Lee

Affiliation: Allina Health

Abstract Preview: Purpose: To assess the feasibility of a dynamic-platform integrated with high-resolution patient-specific-quality-assurance (PSQ device for periodic quality assurance (PQA) and PSQA in respiratory-gat...

Fully Automatic Pipelines for Anatomical ROI Detection and Exposure Index Calculation in X-Ray Imaging : Foundation Model-Based Frameworks for Dose Standardization

Authors: Yoonha Eo

Affiliation: Yonsei University

Abstract Preview: Purpose: To develop a fully automatic and unsupervised algorithm for estimating the Exposure Index (EI) of various Regions of Interest in X-ray imaging using advanced foundation models. Traditional EI...

GPU Accelerated Monte Carlo Simulation for Tset Dose Calculation

Authors: Veng Jean Heng, Jan P. Seuntjens, Timothy C. Zhu, Yifeng Zhu

Affiliation: Department of Radiation Oncology, Stanford University, Princess Margaret Cancer Centre & University of Toronto, University of Pennsylvania

Abstract Preview: Purpose: We have developed a GPU-accelerated Monte Carlo (MC) simulation to determine the cumulative dose distribution of patients undergoing Total Skin Electron Therapy (TSET) using the Stanford tech...

GPU-Accelerated Beamlet and Full Dose Calculations for Efficient Radiation Therapy Planning

Authors: Girish Bal, Jan Kralj, Ayan Mitra, PhD, Ling Shao, Matjaz Subic, Yevgen Voronenko

Affiliation: RefleXion Medical, Cosylab

Abstract Preview: Purpose: This work enhances the efficiency of radiation therapy treatment planning by optimizing the beamlet dose matrix and full patient dose computations using GPU acceleration. The Collapsed-Cone C...

Hypersight-Archer Study: Improved Target Coverage and Organ-at-Risk Sparing Via Adaptive Radiotherapy of Head and Neck Cancer Using Direct-Dose Calculation on Cone Beam CT

Authors: Cheryl Anderson, Lara Best, Amanda Cherpak, Jennifer DeGiobbi, Marc C. LeBlanc, R. Lee MacDonald, Peter R. Martin, Natasha McMaster, Murali Rajaraman, James L. Robar, Lucy Ward, Derek Wilke, Kenny Zhan

Affiliation: Department of Radiation Oncology, QE2 Cancer Centre, Nova Scotia Health

Abstract Preview: Purpose: This work investigates the potential benefit of adaptive planning using the Ethos radiotherapy system (Varian Medical Systems) with direct-dose calculation on HyperSight cone beam CT (CBCT) f...

Impact of Tissue Heterogeneity on Proton LET and RBE Distributions: A Monte Carlo Study

Authors: Xiangli Cui, Wei Han, Jie Li, Lingling Liu

Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Hefei Cancer Hospital, Chinese Academy of Sciences, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences

Abstract Preview: Purpose: To investigate the influence of tissue heterogeneity on proton beam linear energy transfer (LET) and relative biological effectiveness (RBE) using nine RBE models. This study quantifies the i...

Influence of Treatment Site on Lung Shunt Fraction Estimation in 90y-Radioembolization Planning: Comparison of Planar and SPECT Imaging-Based Quantification

Authors: Lukas M. Carter, Jazmin Schwartz

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Accurate lung shunt fraction (LSF) estimation is essential for the safety and efficacy of 90Y-radioembolization therapy. This study compares planar gamma camera imaging and tomographic SPECT-...

Innovative Workflow for Enhanced in-Vivo Dosimetry Using Gafchromic Film

Authors: Salim Balik, Nguyen Phuong Dang, Hualin Zhang

Affiliation: Radiation Oncology, Keck School of Medicine of USC

Abstract Preview: Purpose: An accurate and convenient monitoring of radiation dose delivery during treatment is essential for ensuring patient safety and treatment efficacy. This project aims to develop innovative algo...

Mesh-Based Multiregion Model of Adult Human Kidneys for Dosimetric Evaluation of Radiopharmaceutical Therapy

Authors: John P. Aris, Wesley E. Bolch, Chansoo Choi, Carlos G. Colon-Ortiz, Robert Joseph Dawson, Abdul-Vehab Dozic, Amy M. Geyer, Harald Paganetti, Shreya P. Pathak, Julia D. Withrow

Affiliation: St. Luke's Health System, Massachusetts General Hospital, University of Florida

Abstract Preview: Purpose: The goal of this study was to enhance the accuracy of renal dosimetry in radiopharmaceutical therapy (RPT) by developing a more detailed and precise kidney model. In RPT, accurate dose estima...

Moving Away from Measuring Everything - Implementing 3D Recalculation in a Large Networked Radiotherapy Institution to Replace Routine IMRT / VMAT QA

Authors: Eujin Chan, Christopher Colyer, Leon F Dunn, Jonathan Dunning, Michael Grace, Onno Kamst, Alex Livingstone, Thulani Nyathi, Vladimir Sashin, Philip Satory, Hilmar Schachenmayr, Brindha Subramanian, Lindsay J. Tremethick, Luke Webb

Affiliation: GenesisCare

Abstract Preview: Purpose: The purpose of this work is to outline the methodology and results from the implementation of a 3D recalculation software to replace IMRT/VMAT PSQA measurement across a large, networked radio...

Optimizing Dosimetry in Rpt Clinics: Tackling Initial Hurdles and Ensuring Image Accuracy.

Authors: Siju C. George, Alonso N. Gutierrez, Vivek Mishra, Ranjini P. Tolakanahalli

Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute

Abstract Preview: Purpose: This presentation focuses on optimizing dosimetry in RPT clinics by tackling initial setup challenges and ensuring the accuracy of SPECT/CT imaging for dosimetry. It will address the qualific...

Parameterized Dosimetric Models of the Lumbar Vertebrae for Patient-Informed Active Marrow Dosimetry in Radiopharmaceutical Therapy

Authors: Wesley E. Bolch, Chansoo Choi, Robert Joseph Dawson, Michael Lassmann, Maikol Salas-Ramirez, Bangho Shin, Johannes Tran-Gia, Yitian Wang

Affiliation: Department of Nuclear Medicine, University Hospital Würzburg, University of Florida

Abstract Preview: Purpose: Conduct a parameterized library of mesh-type skeletal models across the lumbar vertebrae. In radiopharmaceutical dosimetry, the hematopoietic active bone marrow is typically a dose-limiting n...

Preclinical Dosimetric Evaluation for Small Animal Study to Investigate Normal Tissue-Sparing Effects in the Electron Ultra-High Dose-Rate (FLASH) Environment

Authors: Ashok Bhandari, Andrew Joseph Fanning, Kyle J. Gallagher, Brendan Graff, Christopher Jenkins, Kyuhak Oh, Ying Yan, Su-Min Zhou

Affiliation: University of Nebraska Medical Center

Abstract Preview: Purpose: This study aimed to design a robust experimental setup to ensure accurate dose delivery using ultra-high-dose-rate for small animal experiments by conducting dosimetric evaluations prior to a...

Prior-Model-Free Dynamic CBCT Reconstruction Via Combined Optical Surface and X-Ray Imaging

Authors: Hua-Chieh Shao, Guoping Xu, You Zhang, Tingliang Zhuang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Advancements in onboard X-ray hardware allow high-quality CBCT imaging with a short scan time (~6s for Varian HyperSight), enabling CBCT-based dose calculation and treatment planning. Howe...

Small Fields Output Factor Measurements in 1.5 MR-Linac

Authors: Thomas I. Banks, Tsuicheng D. Chiu, Viktor M. Iakovenko, Christopher Kabat, Chang-Shiun Lin, Mu-Han Lin, Arnold Pompos

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX

Abstract Preview: Purpose: The superior soft-tissue contrast provided by MR imaging offers favorable conditions for the effective application of stereotactic body radiation therapy (SBRT). Accurate small field dosimetr...

Streamlined Stereotactic Radiosurgery (SRS) Commissioning Experience with a 6FFF Beam for an Elekta Versa: A Clinical Overview for Increased Precision.

Authors: Asma Amjad, Slade J. Klawikowski, Natalya V. Morrow, Haidy G. Nasief, Eric S. Paulson, An Tai, Hualiang Zhong

Affiliation: Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Accurate and precise linac-based SRS commissioning can be very challenging. Thus, it is important to increase the confidence in the measurement at each step prior to end-to-end testing. The p...

The Root Cause of Large Differences in Calculated Beam Monitor Units between a Treatment Planning System and a QA Software

Authors: George X. Ding, Kenneth L. Homann

Affiliation: Vanderbilt University Medical Center

Abstract Preview: Purpose: It is standard practice that the beam monitor units (MUs) calculated by a commercial treatment planning system (TPS) is verified by a secondary dose calculation (SDC) software that independen...

Total Body Irradiation Using Field-in-Field Treatment Planning Techniques

Authors: Kazi Towmim Afrin, Imad M. Ali, Jordan West

Affiliation: University of Oklahoma Health Sciences Center, University of Oklahoma

Abstract Preview: Purpose: To simulate total-body-irradiation (TBI) with field-in-field treatment planning techniques and test portal dosimetry for dose verification and quality assurance.
Methods: CT images of full...

Transforming CT Technologist Training: Real-Time Feedback, Gamification, and Phantom-Based Education for Accurate Patient Positioning

Authors: Rebecca Lamoureux, Zahra (Zara) Razi, Zachary Whipps

Affiliation: University of New Mexico Hospital

Abstract Preview: Purpose: Patient mispositioning in CT imaging contributes to inconsistent radiation dose delivery and suboptimal image quality, impacting patient safety and diagnostic outcomes. This study evaluates a...

Treatment Dose Reconstruction of Digitized Deliveries on Reflexion X1 System Based on Megavoltage Imager and Dose Monitor Chamber

Authors: Angela J Da Silva, Andrew Groll, Gopinath Kuduvalli, Thomas Laurence, David W. Meer, Manoj Narayanan, Mingshan Sun, Don Vernekohl, Ray Yang

Affiliation: RefleXion Medical

Abstract Preview: Purpose: To implement post-treatment review of delivered dose fractions on RefleXion X1 accounting for independent detection of transmitted beamlets and transient dose fluctuations of individual pulse...

Treatment Machine Matching for ELM in Eclipse v18.0 By Adjusting Physical Leaf Gap

Authors: Quyen Duong, Si Young Jang, Soyoung Lee, Samuel Ming Ho Luk

Affiliation: Boston University, Department of Radiation Oncology, University of Vermont Medical Center, Boston Medical Center

Abstract Preview: Purpose: To investigate the clinical impact of physical MLC gaps changes with Millennium 120 MLC on Enhanced Leaf Modeling (ELM) and patient plans, and to establish a new MLC model in Eclipse v18.0 on...

Treatment Planning System Modelling of a New Commercial Rotational Table

Authors: Michael Armstrong, Courtney R. Buckey, Quan Chen, Suzanne J. Chungbin, Mirek Fatyga, Yi Rong, Jun Tan, Xiang Sheng Yan

Affiliation: Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose: To model a commercial rotational table in treatment planning system (TPS) for accurate dose optimization and calculation.

Methods: A commercial rotational table (CDR Equilibrium®) is r...

Treatment Planning System for Uhdr Mobetron: Refinement and Validation of Phase Space Data Input

Authors: Rafael Carballeira, Tianyuan Dai, David J. Gladstone, Philip Von Voigts-Rhetz, Rongxiao Zhang

Affiliation: Shandong Cancer Hospital, Dartmouth College, IntraOp, Thayer School of Engineering, Dartmouth College, University of Missouri

Abstract Preview: Purpose: To analyze phase space (PHSP) data generated for Mobetron in FLASH radiotherapy and assess key dosimetric characteristics, including the energy spectrum, scattering angle distribution, and pe...

Tumor Density on Time-Weighted Mid-Position Images for Thoracic Tumors

Authors: Katrinus Keijnemans, Eric S. Paulson, An Tai

Affiliation: Department of Radiotherapy, University Medical Center Utrecht, Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Time-weighted mid-position images (MidPs), derived from four-dimensional computed tomography (4DCT) via deformable image registration (DIR), are frequently selected for treatment planning due...

Uncertainty in Contralateral Breast Dose Reconstruction for Breast Cancer Radiotherapy Patients in the United States between 1990 and 2012

Authors: Amy Berrington de Gonzalez, David Borrego, Rochelle Curtis, Gretchen L Gierach, Jae Won Jung, Choonik Lee, Choonsik Lee, Matthew Mille, Lene Veiga, Jacqueline Vo

Affiliation: University of Michigan, East Carolina University, Radiation Protection Division, Office of Radiation and Indoor Air, U.S. Environmental Protection Agency, National Cancer Institute, Institute of Cancer Research

Abstract Preview: Purpose: Radiotherapy is vital for treating breast cancer, but its long-term health effects remain a concern. Accurate dose reconstruction is crucial for evaluating risks in retrospective epidemiologi...

Universal MR-to-Synthetic CT: A Streamlined Framework for MR-Only Radiotherapy Planning

Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose:
Converting MR images to synthetic CT (MR2sCT) is highly desirable as it streamlines the radiotherapy treatment planning workflow. This approach leverages the superior soft tissue visibilit...

Using a Generative Adversarial Network (GAN) for Source Particle Generation in Monte Carlo Radiation Therapy Simulations

Authors: Jiankui Yuan, Dandan Zheng, Tingliang Zhuang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Rochester, Varian Medical Systems, Advanced Oncology Solutions

Abstract Preview: Purpose: In Monte Carlo (MC) radiation therapy dose calculations, latent variance exists when directly applying phase-space files (PSF) with a finite number of source particles, while the latter is pr...

Utilization of Log File Analysis to Determine Deliverability of VMAT Plans As a Function of Plan Complexity

Authors: Jameson T. Baker, Sean T Grace, Cindy Pham, Michael A. Trager

Affiliation: Northwell

Abstract Preview: Purpose:
In VMAT planning, increasing complexity in MLC motion and modulation may improve dose distributions and OAR sparing while maintaining PTV coverage. However, increasing complexity can creat...

Validation of Radiopharmaceutical Therapy (RPT) Dose Calculation Platforms from Absolute Absorbed Dose Measurement of 225ac

Authors: Bryan Bednarz, Larry A. DeWerd, Sean Jollota, Ahtesham Ullah Khan, Ohyun Kwon, Jeff Radtke

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison

Abstract Preview: Purpose: The accurate quantification of absorbed dose is essential for alpha-emitting radionuclides used in radiopharmaceutical therapy (RPT). This study presents the first direct comparison of physic...

Validation of SRS Mapcheck for Patient-Specific Quality Assurance of Cyberknife

Authors: Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, Tae Ho Kim, Sangmin Lee

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine

Abstract Preview: Purpose: The CyberKnife system, designed for stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), considers SRS MapCHECK an effective tool for patient-specific QA (PSQA). This wo...