Authors: Sreejesh MS, Subramani Vellaiyan
Affiliation: Kuwait Cancer Control Center, All India Institute of Medical Sciences
Abstract Preview: Purpose: Bibliometric analysis is a powerful statistical tool for evaluating scientific literature and identifying research trends through the quantitative assessment of scholarly output. This study a...
Authors: Jiayi Chen, Manju Liu, Ning Wen, Haoran Zhang, Yibin Zhang
Affiliation: Department of Radiation Oncology, Ruijin Hospital, Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Duke Kunshan University, Department of Radiation Oncology,Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Abstract Preview: Purpose: This study introduces a novel Dual Energy CT (DECT)-Guided Intelligent Radiation Therapy (DEIT) platform designed to streamline and optimize the radiotherapy process. The DEIT system combines...
Authors: Courtney R. Buckey, Jay W. Burmeister, Minsong Cao, Grace Chang, Yu Kuang, Yixiang Liao, Yi Rong, Dandan Zheng
Affiliation: Mayo Clinic, Mayo Clinic Arizona, Karmanos Cancer Center, Gershenson ROC, Wayne State University School of Medicine, Department of Radiation Oncology, University of California, Los Angeles, Medical Physics Program, University of Nevada, Rush University Medical Center, University of Rochester
Abstract Preview: Purpose: Investigate the adequacy of training for therapeutic medical physics residents in select special procedures.
Methods: After a review of existing literature, a multi-institutional group dev...
Authors: Grant Evans, Maxwell Arthur Kassel, Charles Shang, Stephen Shang
Affiliation: South Florida Proton Therapy Institute, SFPRF
Abstract Preview: Purpose: Proton pencil beam scanning therapy is particularly sensitive to field translational shifts and beam range variations, which can degradation of dose distribution and compromise the treatment....
Authors: Zachary Diamond, Pretesh Patel, Sibo Tian, Xiaofeng Yang, David Yu, Ahmal Jawad Zafar, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose:
We propose a method to optimize adaptive proton FLASH therapy (ADP-FLASH) using modularized pin-ridge filters (pRFs) by recycling module pins from the initial plan, reducing pRF adjustment...
Authors: Cem Altunbas, Farhang Bayat
Affiliation: Department of Radiation Oncology, University of Colorado School of Medicine, Taussig Cancer Center, Cleveland Clinic
Abstract Preview: Purpose:
Low dose imaging and scatter rejection hardware in CBCT reduces X-ray fluence incident on the imager, increasing noise, causing photon starvation artifacts in CBCT images. In this work, we...
Authors: Ergun E. Ahunbay, Abdul Parchur, Eric S. Paulson, Ilaria Rinaldi, Angelo Schiavi, Li Zhao
Affiliation: Sapienza University of Rome, Department of Radiation Oncology (Maastro), GROW School for Oncology, Maastricht University Medical Centre+, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Online adaptive replanning is often necessary in Intensity Modulated Proton Therapy (IMPT) due to the sensitivity of proton dose distributions to daily anatomical changes. A rapid, automated ...
Authors: Matthew J Ferris, Jason K Molitoris
Affiliation: Department of Radiation Oncology, University of Maryland School of Medicine, University of Maryland
Abstract Preview: Purpose: Anatomy changes often happen in head-and-neck (HN) patients treated with proton radiation therapy. These changes can result in deteriorations of target dose coverage and increased dose to org...
Authors: Mark E Artz, Julie Bradley, Hardev Singh Grewal, Perry B. Johnson, Christina Klassen, Raymond Mailhot Vega, Nancy Mendenhall, Jiyeon Park, Emma V. Viviers, Yawei Zhang
Affiliation: UF Health Proton Therapy Institute, University of Florida
Abstract Preview: Purpose: Verification CTs (VFCT) are used in radiotherapy to assess patient dose during treatment. However, they are time-consuming and contribute additional radiation exposure to the patient. This st...
Authors: Austen N. Curcuru, Arash Darafsheh, Winter Green, Yao Hao, Baozhou Sun, Tiezhi Zhang, Tianyu Zhao, Xiandong Zhao
Affiliation: WashU Medicine, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine, Washington University in St. Louis, University of South Florida, Baylor College of Medicine
Abstract Preview: Purpose: Intensity modulated proton therapy (IMPT) requires precise setup imaging due to the sharp dose gradients and rapid distal fall-off seen in proton therapy dose distributions. Additionally, onl...
Authors: Brian Burger, Carri K. Glide-Hurst, John W. Hayes, Carson Hoffman, Minglei Kang, Jessica R. Miller, Jordan M. Slagowski, Yuhao Yan
Affiliation: Department of Human Oncology, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Leo Cancer Care
Abstract Preview: Purpose: The combination of upright CT and patient positioner for particle therapy present tremendous potential for high precision IGRT and online adaptive radiation therapy (ART), where reliable CT p...
Authors: Xiaoda Cong, Rohan Deraniyagala, Xuanfeng Ding, Xiaoqiang Li, Jian Liang, Peilin Liu, Craig Stevens, Xiangkun Xu, Weili Zheng
Affiliation: Corewell Health William Beaumont University Hospital, Corewellhealth William Beaumont University Hospital, William Beaumont University Hospital, Corewellhealth William Beaumont Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital
Abstract Preview: Purpose:
Commission a step-and-shoot arc therapy(SPArc-step&shoot) for treating head-neck cancer patients as a desired interim milestone toward full dynamic treatment.
Methods:
An in-house de...
Authors: Derek Tang, Susu Yan
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: To evaluate the performance of a multi-task automated-segmentation and synthetic CT generation model (sCT) and investigate its application in an adaptive proton therapy workflow.
Methods: ...
Authors: Thomas R. Bortfeld, Prof. Elisabetta De Bernardi, Tianxue Du, Beatrice Foglia, Chiara Gianoli, Takamitsu Masuda, Katia Parodi, Marco Pinto, Boon-Keng Kevin Teo, Yunhe Xie
Affiliation: Department Of Radiation Oncology, Massachusetts General Hospital (MGH), School of Medicine and Surgery, University of Milano-Bicocca, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, National Institutes for Quantum Science and Technology (QST), University of Pennsylvania, Department of Experimental Physics - Medical Physics, Ludwig-Maximilians-Universität (LMU) München
Abstract Preview: Purpose: The full potential offered by protons in clinical practice is limited by range uncertainties. One possibility for monitoring is through secondary prompt gammas (PG). PG emission along the pen...
Authors: Daniel H. Bushe, Arthur Lalonde, Hoyeon Lee, Harald Paganetti, Brian Winey
Affiliation: Universite de Montreal, Massachusetts General Hospital, Massachusetts General Hospital and Harvard Medical School, University of Hong Kong
Abstract Preview: Purpose: Improving the precision and fidelity of daily volumetric imaging is essential for enabling adaptive proton therapy (APT). While cone-beam CT (CBCT) provides daily volumetric imaging, their ut...
Authors: Kristina Bjegovic, Yong Chen, Lucia Rodriguez Gonzalez, Marti Roper, Liangzhong Xiang
Affiliation: University of California, Irvine, University of California Irvine, University of Oklahoma Health Sciences Center, University of Oklahoma Health Science Center
Abstract Preview: Purpose: Proton therapy is an increasingly popular cancer treatment due to its precision, enabled by the Bragg Peak (BP), which minimizes side effects. This profile necessitates in-patient localizatio...
Authors: Yuzhen Ding, Hongying Feng, Jason Michael Holmes, Baoxin Li, Wei Liu, Daniel Ma, Lisa McGee, Samir H. Patel, Jean Claude M. Rwigema, Sujay A. Vora
Affiliation: Arizona State University, Department of Radiation Oncology, Mayo Clinic, Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose:
Intensity-modulated proton therapy (IMPT) is a preferred treatment modality for head and neck (H&N) cancer patients, offering precise tumor targeting while sparing surrounding organs at ri...
Authors: Akbar Anvari, Carnell J. Hampton, Melanie R. Piantino, Kai Yang
Affiliation: Levine Cancer Institute, Atrium Health
Abstract Preview: Purpose: To evaluate aperture collimation on a C-shape gantry-mounted proton accelerator. Mevion S250i Hyper scanning machine implemented aperture collimation utilizing adaptive aperture (AA). The AA ...
Authors: Robbie Beckert, Weiren Liu, Thomas R. Mazur, Allen Mo, Stephanie Perkins, Hailei Zhang, Tianyu Zhao
Affiliation: Washington University in St. Louis School of Medicine, University of South Florida, WashU Medicine
Abstract Preview: Purpose: Online adaptation may mitigate uncertainties in proton therapy arising from interfractional anatomical changes. While robust optimization accounts for setup and range uncertainties during pla...
Authors: Ergun E. Ahunbay, Abdul Kareem Parchur, Eric S. Paulson, Ilaria Rinaldi, Angelo Schiavi, Li Zhao
Affiliation: Sapienza University of Rome, Department of Radiation Oncology (Maastro), GROW School for Oncology, Maastricht University Medical Centre+, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Secondary dose calculations (SDC) facilitate patient-specific quality assurance for online adaptive intensity-modulated proton therapy (IMPT). However, there is currently a lack of commercial...
Authors: Claus Belka, Stefanie Corradini, George Dedes, Nikolaos Delopoulos, Christopher Kurz, Guillaume Landry, Ahmad Neishabouri, Domagoj Radonic, Adrian Thummerer, Niklas Wahl, Fan Xiao
Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, LMU Munich, Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), National Center for Radiation Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO)
Abstract Preview: Purpose: In MR-guided online adaptive radiotherapy, MRI lacks tissue attenuation information necessary for accurate dose calculations. Instead of using deep learning methods to generate synthetic CT i...
Authors: Michael Dohopolski, Jiaqi Liu, Hao Peng, Robert Timmerman, Zabi Wardak, Haozhao Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
This study introduces a gradient-based radiomics framework to enhance outcome prediction in Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR) for brain metastases...
Authors: Philip Blumenfeld, Jon Feldman, Yair Hillman, Michael Marash, Aron Popovtzer, Alexander Pryanichnikov, Shimshon Winograd, Marc Wygoda, Vered Zivan
Affiliation: Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), P-Cure Ltd./Inc., Sharett Institute of Oncology, Hadassah Medical Center, Hebrew University of Jerusalem
Abstract Preview: Purpose:
Image-guided adaptive proton therapy (IGAPT) allows tailored dose adjustments to account for anatomical and physiological changes during treatment. Recent efforts have developed a cost-eff...
Authors: Hania A. Al-Hallaq, Duncan Henry Bohannon, Chih-Wei Chang, Anees H. Dhabaan, Vishal Dhere, H Scott McGinnis, Pretesh Patel, Sagar Patel, Keyur Shah, Xiaofeng Yang, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Two-fraction proton SABR is an attractive alternative to brachytherapy for localized prostate cancer. However, potential interfractional anatomical changes necessitate online adaptation, espe...
Authors: Gregory Bolard, Rabten Datsang, Sarah Ghandour, Timo Kiljunen, Pauliina Paavilainen, Sami Suilamo, Katlin Tiigi
Affiliation: Turku University Hospital, Virginia Commonwealth University, MVision AI, North Estonia Medical Centre, Docrates Cancer Center, Hopital Riviera-Chablais
Abstract Preview: Purpose: To verify the performance of a vendor-neutral deep learning model for synthetic CT generation from T2-weighted and balanced steady-state MR sequences to support both MR-only simulation and MR...
Authors: Rachel B. Ger, Heng Li, Anh Tran
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Proton therapy patients undergo quality assurance CT scans (QACTs) during treatment to verify dosimetric accuracy and utilize robustness scenarios for setup and range uncertainties. For intra...
Authors: Curtiland Deville, Rachel B. Ger, Heng Li, Todd R. McNutt
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Proton therapy patients receive quality assurance CT scans (QACTs) during treatment to verify dosimetric accuracy and determine adaptive therapy needs as proton treatments are highly sensitiv...
Authors: Malvern Madondo, Mark McDonald, Zhen Tian, Christopher Valdes, Ralph Weichselbaum, Xiaofeng Yang, David Yu, Jun Zhou
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Chicago, Emory University, Department of Radiology, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Head-and-neck (HN) cancer patients often experience significant anatomical changes during treatment course. Proton therapy, particularly intensity-modulated proton therapy (IMPT), is sensitiv...
Authors: Qijie Huang, Gourav Jhanwar, Saad Nadeem, Vicki Trier Taasti, Mojtaba Tefagh, Seppo Tuomaala, Masoud Zarepisheh
Affiliation: Varian Medical Systems Inc, Department of Clinical Medicine - Danish Center for Particle Therapy, Aarhus University Hospital, Memorial Sloan Kettering Cancer Center, The University of Edinburgh
Abstract Preview: Purpose:
We have developed PortPy (Planning and Optimization for Radiation Therapy in Python), a first-of-its-kind open-source package designed to accelerate research and development in radiotherap...
Authors: Liangzhong Xiang
Affiliation: University of California, Irvine
Abstract Preview: N/A...
Authors: Austen N. Curcuru, Winter Green, Yao Hao, Jiayi Liu, Yuting Peng, Tiezhi Zhang, Xiandong Zhao
Affiliation: Washington University School of Medicine, Department of Radiation Oncology, WashU Medicine, Virginia Commonwealth University, Washington University School of Medicine, Washington University in St. Louis
Abstract Preview: Purpose: We proposed a treatment planning optimization method that utilizes customized spot map modification to achieve less dosimetry uncertainty, monitor unit ratio (MUR) and neutron dose in a spot ...
Authors: Ozgur Ates, Chin-Cheng Chen, Chia-Ho Hua, Matthew J. Krasin, Thomas E. Merchant
Affiliation: St. Jude Children's Research Hospital
Abstract Preview: Purpose: To validate the use of synthetic CTs generated from CBCT images for online monitoring, ensuring accurate and reliable daily plan quality assessments in adaptive proton therapy (APT).
Metho...