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Results for "advanced treatments": 99 found

3D Topological Features for Outcome Assessment of Therapeutic Responses to Neoadjuvant Chemoradiotherapy (NCRT) with and without Anti-CD40 Immunotherapy in Local Advanced Rectal Cancer (LARC)

Authors: Todd A Aguilera, Gaurav Khatri, Jiaqi Liu, Hao Peng, Nina N. Sanford, Robert Timmerman, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT southwestern medical center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
This study first integrates 3D topological data analysis with radiomics from local advanced rectal cancer T2-weighted MRI to evaluate therapeutic responses and quantify treatment-induced c...

A Foundational Model for Medical Imaging Modality Translation in Head and Neck Radiotherapy

Authors: Jie Deng, Yunxiang Li, Xiao Liang, Weiguo Lu, Jiacheng Xie, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Recently, foundational models trained on large datasets have shown remarkable performance across various tasks. Developing a foundational model for medical image modality translation in head-...

A Multi-Omics Approach for Predicting Acute Hematologic Toxicity in Patients with Cervical Cancer Undergoing External-Beam Radiotherapy

Authors: Sijuan Huang, Yongbao Li

Affiliation: Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, Guangdong, 510060, China, Sun-Yat sen University Cancer Center

Abstract Preview: Purpose: Hematologic toxicity (HT) is one of the most prevalent treatment-related toxicities experienced by locally advanced cervical cancer (LACC) patients receiving radiotherapy (RT). This study aim...

A Multi-Regional and Multi-Omics Approach to Predict Penumonitis in Patients with Locally Advanced Non-Small Cell Lung Cancer in Nrg Oncology Trial RTOG 0617

Authors: Katelyn M. Atkins, Indrin J. Chetty, Elizabeth M. McKenzie, Taman Upadhaya, Samuel C. Zhang

Affiliation: Department of Radiation Oncology,Cedars-Sinai Medical Center, Cedars-Sinai Medical Center

Abstract Preview: Purpose:
We explored a multi-regional and multi-omics approach to extract CT-based radiomics and 3D dosiomics features to predict radiation pneumonitis (RP) in patients with locally advanced Non-Sm...

A Python Package for GPU-Accelerated Photon Dose Calculation for Advanced and Generalizable Auto-Planning Approaches: Validation for Multiple Linear Accelerator Vendors and Institutions

Authors: Jaryd Ricardo Christie, Anthony J. Doemer, William T. Hrinivich, Junghoon Lee, Calin Reamy, Kundan S Thind

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, Henry Ford Health

Abstract Preview: Purpose: To develop and validate an open-source Python package for fast, widely compatible, and user-friendly photon dose calculation algorithm through comparisons with clinical treatment planning sys...

A Topological Technique to Unify Image Texture and Morphology to Enhance Radiomic Feature Representations

Authors: David Brizel, Kyle J. Lafata, Jian-Guo Liu, Yvonne M Mowery, Yvonne M Mowery, William Paul Segars, Jack B Stevens

Affiliation: Department of Physics, Duke University, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh

Abstract Preview: Purpose: To develop a technique to quantify tumor topology using a unifying mathematical framework that integrates texture and morphology and to evaluate its feasibility as a prognostic biomarker for ...

A Two-Layer, Two-Task Prediction Model Based on 3D Imaging and Residual Networks for Mid-Chemoradiation Tumor Response Prediction on FDG PET for La-NSCLC

Authors: Stephen R. Bowen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Jing Sun, Jiajie Wang, Shouyi Wang, Faisal Yaseen, Xiaojing Zhu

Affiliation: Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Shanghai University of Electric Power, Fred Hutchinson Cancer Center, University of Texas at Arlington

Abstract Preview: Purpose: Accurate prediction of patient response to radiotherapy plays a crucial role in monitoring disease progression and assessing treatment efficacy, enabling clinicians to develop personalized th...

AI-Assisted Cellular and Organoid Analysis for Lenalidomide-Based Radioimmunotherapy Against Glioblastoma

Authors: ISAAC Amoah, Jackie Austin, Charlotte Block, Kaylee Brilz, Dylan Bui, Andrew E. Ekpenyong, Jayce Hughes, Pralhad Itani, Natasha Ratnapradipa, Sara Strom, Jacob Woolf

Affiliation: Creighton University

Abstract Preview: Purpose:
Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults, with a median survival of approximately 15 months despite the current standard of care, which includes s...

Advanced Daily Imaging Technology Improves Tracking of Soft Tissue Decomposition for Head and Neck Cancer Patients Receiving Radiotherapy

Authors: Robert K Chin, Klea Hoxha, Erika Jank, Jesus Juarez, Eulanca Yuka Liu, Dylan P. O'Connell, X. Sharon Qi, Ricky R Savjani

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, Los Angeles, UCLA Radiation Oncology

Abstract Preview: Purpose:
Daily cone beam CT (CBCT) images are acquired prior to each radiotherapy treatment for verifying patient positioning. HyperSight is an advanced imaging solution that replaces standard CBCT...

Advanced Modeling of Singlet Oxygen Distribution in Pleural Cavity Photodynamic Therapy Using Validated Geometric Standardization

Authors: Hongjing Sun, Timothy C. Zhu

Affiliation: University of Pennsylvania

Abstract Preview: Purpose: This study aims to develop a model of singlet oxygen distribution in pleural photodynamic therapy (PDT) by combining standardized anatomical coordinates with CT-validated geometry reconstruct...

Advancing Cardiac Sparing with Upright Patient Geometry and Deep Learning

Authors: Shae Gans, Carri K. Glide-Hurst, Mark Pankuch, Chase Ruff, Niek Schreuder, Nicholas R. Summerfield, Yuhao Yan

Affiliation: Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Northwestern Medicine Proton Center, Northwestern Medicine Chicago Proton Center, Leo Cancer Care

Abstract Preview: Purpose: Novel upright patient positioners coupled with diagnostic-quality vertical CT at treatment isocenter introduce a significant opportunity for improved image-guided particle therapy. Treating p...

An Advanced Automated Pipeline for Brain Tumor Segmentation on MRI Images in Gamma Knife Radiotherapy

Authors: Zachery Colbert, Matthew Foote, Michael Huo, Mark Pinkham, Prabhakar Ramachandran, Mihir Shanker

Affiliation: Radiation Oncology, Princess Alexandra Hospital, Ipswich Road, Princess Alexandra Hospital

Abstract Preview: Purpose: The study aimed to develop and implement deep learning-based autosegmentation models for the autosegmentation of four key tumor types: brain metastasis, pituitary adenoma, vestibular schwanno...

An Automated Notification System for Identifying Patients Eligible for Biology-Guided Radiotherapy

Authors: Shahed Badiyan, Bin Cai, Tu Dan, Michael Dohopolski, Steve B. Jiang, Deepkumar Mistry, Arnold Pompos, Robert Timmerman, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Biology-guided radiotherapy (BGRT) offers significant potential for personalized and adaptive cancer treatment, with clinically available systems such as SCINTIX from Reflexion now being intr...

An End-to-End Test for Adaptive Radiotherapy with Varian Hypersight CBCT Imaging System Using Radiochromic Film in a Rando Pelvis Phantom

Authors: Jameson T. Baker, Yijian Cao, Jenghwa Chang, Sean T Grace, Lyu Huang, Jian Liu, Echezona Simon Obi, Anurag Sharma

Affiliation: Northwell, Hofstra University Medical Physics Program

Abstract Preview: Purpose:
To validate the end-to-end dosimetrical accuracy of Varian HyperSight CBCT for adaptive radiotherapy (ART), from simulation to dose delivery, using radiochromic film dosimetry in a Rando p...

Application and Analysis of Advanced 3D Printed Materials As Bolus for Radiation Therapy

Authors: Rami M. Shorti, Gary R. Stinnett

Affiliation: Intermountain Health, Radiation Oncology, Intermountain Health, Advanced Visualization Engineering Department

Abstract Preview: Purpose: In this work we present the workflow, materials analysis, and lessons learned from leveraging advanced 3D printing Polyjet Technology to print conformal bolus for radiation therapy.
Method...

Assessing an Improvement to Hyperarc SRS Planning: Comparing the Efficiency Index of Hyperarc Alone Vs Hyperarc + Surface Area Informed Optimization

Authors: Ivan L. Cordrey, Dharmin D. Desai, Ellis Lee Johnson

Affiliation: Cumberland Medical Center - Cancer Center, University of Kentucky, Varian Advanced Oncology Solutions

Abstract Preview: Purpose: HyperArc (HA) is known to produce a high quality SRS plan. Adding Surface Area Informed Optimization (SAIO) to HA has been shown to improve plan quality metrics R50% and the Conformality Inde...

Assessment of Off-Target Dose for Curative Treatment of Pregnant Head and Neck Cancer Case: A Monte-Carlo Study

Authors: Brianna Baek, David J. Carlson, Zhe (Jay) Chen, Dae Yup Han, Bon Tack Koo, Hyojun Park

Affiliation: Columbia University, Canyon Crest Academy, Department of Therapeutic Radiology, Yale University School of Medicine, Department of Radiation Oncology, Chung-Ang University Gwang Myeong Hospital

Abstract Preview: Purpose: To find an optimized treatment technique and shielding design for minimizing the dose to a fetus, a Monte-Carlo simulation was performed to evaluate the dosimetric contribution.
Methods: G...

Assessment of Vasculature Mapping Using Infrared Imaging System for Treatment Planning

Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Maximilian Stephen Meineke, Runhe Tan

Affiliation: The James Cancer Center, The Ohio State University, The Ohio State University - James Cancer Hospital

Abstract Preview: Purpose: The response of healthy vasculature due to radiation treatments is an underexplored area of radiation oncology. Understanding the impact of radiation on veins could advance treatment optimiza...

Automated Case Prioritization in Breast Radiation Therapy Peer Review Rounds

Authors: Leigh A. Conroy, Thomas G Purdie, Christy Wong

Affiliation: Department of Medical Biophysics, University of Toronto, Princess Margaret Cancer Centre

Abstract Preview: Purpose: To develop a novel machine learning (ML) algorithm to evaluate and rank breast radiation therapy (RT) treatment plans based on treatment complexity for prioritization in multidisciplinary pee...

Automated Tool for Radiotherapy Initial Patient Setup: A Robust Approach Based on Vertebral Identification

Authors: Hailun Pan, Yingli Yang, Jie Zhang, Yibin Zhang

Affiliation: Department of Radiation Oncology,Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Department of Radiology, Ruijin Hospital, Department of Radiation Oncology, Ruijin Hospital, , Shanghai Jiaotong University School Of Medicine, Shanghai United imaging Healthcare Advanced Technology Research Institute

Abstract Preview: Purpose: Accurate patient positioning is critical in radiotherapy (RT) to ensure effective treatment delivery and minimize harming surrounding healthy tissues. Vertebral misalignment during RT setup h...

Automatic Tumor Segmentation and Catheter Detection from MRI for Cervical Cancer Brachytherapy Using Uncertainty-Aware Dual Convolution-Transformer Unet

Authors: Majd Antaki, Rohini Bhatia, Gayoung Kim, Yosef Landman, Junghoon Lee, Akila N. Viswanathan

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Physics and Advanced Development Elekta

Abstract Preview: Purpose: Brachytherapy is a standard radiation therapy approach for cervical cancer, which directly delivers radiation source to the tumor using catheters. Treatment planning requires identification o...

Automating Radiographic Sharp Score Prediction in Rheumatoid Arthritis Using Multistage Deep Learning Methods

Authors: Hajar Moradmand, Lei Ren

Affiliation: University of Maryland School of Medicine, University of Maryland

Abstract Preview: Purpose:
The Sharp-van der Heijde (SvH) score is essential for assessing joint damage in rheumatoid arthritis (RA) from radiographic images. However, manual scoring is time-intensive and prone to v...

Beam Orientation Optimization in IMRT Using Sparse Mixed Integer Programming and Non-Convex IMRT Fluence Map Optimization

Authors: Yabo Fu, Yang Lei, Yu Lei, Haibo Lin, Ruirui Liu, Tian Liu, Kenneth Rosenzweig, Charles B. Simone, Shouyi Wei, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York Proton Center

Abstract Preview: Purpose: Beam orientation optimization (BOO) in intensity-modulated radiation therapy (IMRT) is traditionally a complex, non-convex problem tackled with heuristic methods. This study benchmarks global...

Biomechanically Guided Deep Learning for Deformable Multimodality Liver Registration Framework

Authors: Yunfei Dong, Dongyang Guo, Zhenyu Yang, Fang-Fang Yin, Zeyu Zhang

Affiliation: Duke University, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose:
To develop a Biomechanically Guided Deep Learning Registration Network (BG-DRNet) that improves both accuracy and physiological plausibility in liver image registration. While cone-beam CT...

Case-By-Case Analysis of Proton Spot Spacing and Dosimetric Variability in Proton Arc Lung Cancer Planning

Authors: Nebi Demez, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Umesh Rana, Nishan Shrestha, Somol Sunny

Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: DynamicARC is an advanced proton therapy technique that leverages pencil beam scanning to deliver dose to the patient while the gantry rotates around the patient. This study investigates the ...

Comparison of CBCT Dose Calculation Accuracy between Truebeam Hypersight Image Reconstruction Algorithms

Authors: Sarah Aubert, Harald Keller, Jeff D. Winter

Affiliation: Princess Margaret Cancer Centre

Abstract Preview: Purpose: Support for treatment planning directly on CBCT imaging on C-arm linacs will enable adaptive radiation therapy (ART) capacity with increased treatment technique flexibility. The HyperSight im...

Deep Learning-Based Categorization of Brain Tumours Using Brain MRI : Advancing Precision Medicine in Neuroimaging

Authors: William F.B Igoniye, Belema Manuel, Christopher F. Njeh, O Ray-offor

Affiliation: Indiana University School of Medicine, Department of Radiation Oncology, Department of Radiology, University of Port Harcourt Teaching Hospital

Abstract Preview: Purpose: The accurate and efficient categorization of brain tumors is essential for effective treatment planning and improved patient outcomes. Current MRI-based diagnostic methods are time-intensive ...

Denoising Diffusion-Weighted Images of Rectal Cancer Acquired on a 0.35 T Magnetic Resonance Imaging-Guided Linear Accelerator Using Singular Value Decomposition

Authors: Jacqueline M. Andreozzi, Tess Armstrong, Shiva Bhandari, John M Bryant, Jessica M Frakes, David J. Gladstone, Sarah E Hoffe, Kujtim Latifi, Arash Naghavi, Steven Nichols, Ibrahim M. Oraiqat, Russell Palm, Gage H. Redler, Stephen A Rosenberg, Joseph Weygand

Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Thayer School of Engineering, Dartmouth College, Department of Radiation Oncology, Ohio State University, Moffitt Cancer Center, Department of Radiation Oncology, Moffitt Cancer Center

Abstract Preview: Purpose: The MR-linac provides unique opportunities for integrating advanced imaging into radiotherapy workflows, but the lower sensitivity of systems like the 0.35T model can pose challenges for diff...

Development and Clinical Validation of a Tissue Maximum Ratio (TMR)-Based Monitor Units Second Check Script for Dynamic Conformal-Based Hyperarc Brain Radiosurgery Plans Via Scatter Correction Factors

Authors: Jacob Gooslin, Ellis Lee Johnson, Damodar Pokhrel

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, University of Kentucky, Radiation Medicine

Abstract Preview: Purpose: HyperArc radiosurgery permits treatment of multiple brain lesions using a single-isocenter improving treatment planning efficiency and workflow. A key stereotactic planning aspect is an indep...

Development of a Comprehensive Thoracic Re-Irradiation Database and Investigation of Time-Dependent Dose-Recovery Dynamics for Toxicity Modeling

Authors: Victoria Doss, Tsion Gebre, Rachel B. Ger, Esi A Hagan, Elaina Hales, Russell K Hales, Xun Jia, Heng Li, Dezhi Liu, Todd R. McNutt, Meti Negassa, Anas Obaideen, Tinker Trent, K. Ranh Voong, Cecilia FPM de Sousa

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: As cancer care advances, more patients require re-irradiation, yet evidence-based data is lacking. This study aimed to develop a thoracic re-irradiation database and explore time-dependent re...

Development of a Knowledge-Based Planning Model for Optimal Trade-Off Guidance in Locally Advanced Non-Small Cell Lung Cancer

Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, James Tam, Junyi Xia, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai

Abstract Preview: Purpose:
The aim of the study is to develop a trade-off prediction model to efficiently guide the treatment planning process for patients with stage III non-small cell lung cancer (NSCLC).
Metho...

Development of an Ultrafast MR Technique to Detect Linac Radiation Pulses for Biological Imaging on a Clinical 0.35T MR-Linac

Authors: Pierre Gardair, Johnathan E Leeman, Claire Keun Sun Park, Atchar Sudhyadhom

Affiliation: Brigham and Women’s Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School, Harvard Medical School

Abstract Preview: Purpose: Dose is a poor surrogate for radiobiological damage but no in vivo technology exists to directly measure damage such as DNA strand breaks and free radical generation (FRG). Recent advances in...

Diffusion-Weighted MRI: An Early Biomarker for Treatment Response in MR-Guided Treatment of Rectal Cancer

Authors: Huiming Dong, Jonathan Pham, X. Sharon Qi, Ann Raldow

Affiliation: Department of Radiation Oncology, University of California, Los Angeles

Abstract Preview: Purpose: The study aimed to investigate longitudinal apparent diffusion coefficient (ADC) as an early biomarker of treatment response in patients with locally advanced rectal cancer (LARC) undergoing ...

Direct-to-Unit Dose Calculations for Stereotactic Radiosurgery on a C-Arm Linac with Modern on-Board Imaging Solutions

Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Haley K Perlow, Alex T. Price, Atefeh Rezaei, Prashant Vempati, Runyon C. Woods

Affiliation: University Hospitals Seidman Cancer Center

Abstract Preview: Purpose: The HyperSight imaging feature on C-arm linacs(HS-CBCT) offers increased CT number accuracy over conventional on-board imaging. The C-arm geometry allows for noncoplanar treatments common to ...

Dosimetric Analysis of Plans Using X-Ray and X-Îł-Ray Combination Strategy for Advanced Cervical Cancer Patients with Pelvic Lymph Node Metastasis

Authors: Yi Li

Affiliation: Department of Radiation Oncology, the First Affiliated Hospital of Xi'an Jiaotong University

Abstract Preview: Purpose: Advances in radiotherapy technology are crucial for improving cervical cancer (CC) treatment. This study explores a novel X-ray and Îł-ray dual-modality radiation (TaiChiB) system, comparing i...

Dosimetric Assessment of Spatially Fractionated Radiation Therapy on Prostate Cancer Cases: Our Experience in Nsia-Luth Cancer Center, Lagos

Authors: Adebayo Abe, Samuel Olaolu Adeneye, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Sylvester Entonu, Muhammad Habeebu, Adedayo O. Joseph, Oluwaseyi Oderinde, Oluwadara Ojediran, Margaret Dideolu Taiwo

Affiliation: University of Ibadan, University of Lagos, Missouri University of Science and Technology, Purdue University, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre

Abstract Preview: Purpose:
Spatially Fractionated Radiation Therapy (SFRT) is an advanced radiotherapy technique designed to deliver highly heterogeneous radiation doses, aiming to optimize tumor control while minim...

Dosimetric Comparison of MR-Linac Vs. Cyberknife for Prostate Stereotactic Body Radiation Therapy

Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: Prostate stereotactic body radiation therapy (SBRT) requires precise dose delivery to the target volume and organ-at-risk (OAR) sparing. This study compares MR-Linac (MRL) and CyberKnife (CK)...

Dosimetric Evaluation of Clinical Venezia Hybrid Applicator Plans Using a TG-186 Model-Based Dose Calculation Algorithm

Authors: Davide Brivio, Ivan M. Buzurovic, Thomas C. Harris, Desmond A. O'Farrell

Affiliation: Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology

Abstract Preview: Purpose: Cervical cancer can be treated with a brachytherapy boost following external beam radiotherapy. One applicator option is the Advanced Gynecological Applicator "Venezia" (Elekta) hybrid, consi...

Dual-Energy CT Derived Perfusion Blood Volume and 4D-CT Derived Ventilation Changes in Lung Cancer Patients 6-Months Post Radiation Therapy

Authors: Daniel A. Alexander, Jeffrey D. Bradley, Steven J. Feigenberg, Cole Friedes, Casey Hollawell, William Levin, Maksym Sharma, Boon-Keng Kevin Teo, Ying Xiao, Nikhil Yegya-Raman, Jennifer Wei Zou

Affiliation: Department of Radiation Oncology and Applied Sciences, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania

Abstract Preview: Purpose: To investigate lung function changes following definitive chemoradiation dose using CT-derived measurements in patients with locally advanced NSCLC at 6-months post-treatment compared to pre-...

Early Imaging Identification of Osteoradionecrosis and Classification Using the Novel Clinrad System

Authors: Serageldin Attia, Zayne Belal, Cem Dede, Clifton David Fuller, Andrew Hope, Laia Humbert Vidan, Kate Hutcheson, Zaphanlene Kaffey, Stephen Y. Lai, Abdallah Mohamed, Amy Moreno, Jillian Rigert, Erin Watson

Affiliation: Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center; The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Princess Margaret Cancer Centre, University Health Network, 610 University Ave., The University of Texas MD Anderson Cancer Center, UT MD Anderson, Princess Margaret Cancer Centre, UT MD Anderson Cancer Center, Hospital of the University of Pennsylvania, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Head and Neck Surgery, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology

Abstract Preview: Purpose: Osteoradionecrosis (ORN) of the jaw is a debilitating radiation-induced toxicity lacking standardized classification criteria or treatment guidelines. Early identification of tissue injury co...

Empowering Knowledge Transfer in Global Radiotherapy Planning: An Educational Case Study of Knowledge-Based Models in Nepal

Authors: Rita Buono, Elisabetta Cagni, Roberta Castriconi, Surendra Bahadur Chand, Marco Esposito, Claudio Fiorino, Valeria Landoni, Aldo Mazzilli, Eugenia Moretti, Lorenzo Placidi, Giulia Rambaldi Guidasci, Alessia Tudda

Affiliation: IRCCS San Raffaele Scientific Institute, Department of Advanced Technology, IRCCS Regina Elena National Cancer Institute, ASU FC Medical Physics, University Hospital of Parma AOUP, ICTP, B.P. Koirala Memorial Cancer Hospital, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Fatebenefratelli Isola Tiberina – Gemelli Isola

Abstract Preview: Purpose: To explore the feasibility and educational impact of transferring knowledge-based planning (KBP) models—developed using Italian breast radiotherapy data—to a Nepalese hospital, thereby demons...

Equivalent Uniform Dose and Duodenal Toxicity Correlation in Pancreatic Cancer Irradiation

Authors: Samira Dabaghmanesh, Beth A. Erickson, William Hall, Jason Hirshberg, An Tai

Affiliation: Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Treatment plan evaluation for minimizing duodenal toxicity often involves multiple dose-volume constraints that vary based on fractionation. The Equivalent Uniform Dose (EUD) has emerged as a...

Establishing Radiotherapy in Malawi through an International Medical Physics Collaboration

Authors: Ruth Afanador, Daniela Branco, John M Bryant, John Campbell, Clement Chaphuka, Samuel A. Einstein, David B. Flint, Jeffrey R. Kemp, Mussa Kumwembe, Daniel J Mollura, Joseph Weygand

Affiliation: RAD-AID International, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, UNC Health, Malawi National Cancer Center, Kamuzu Central Hospital, Penn State College of Medicine, Sutter Health, New York University, University of California San Diego / California Protons, Department of Radiation Oncology, Moffitt Cancer Center

Abstract Preview: Purpose: Malawi, a landlocked country in southeastern Africa with a population of over 20 million, ranks among the world’s least-developed nations and has the fourth-lowest gross domestic product per ...

Establishing a Conventional Linac-Based Electron Flash Beam

Authors: Christopher Bartee, Justin Riley DeFrancisco, Marcos Feijoo, Siyong Kim, Tianjun Ma

Affiliation: Blue Physics LLC, Virginia Commonwealth University

Abstract Preview: Purpose: Irradiation with FLASH has been shown to decrease normal tissue toxicity while maintaining similar tumor control. To advance FLASH into the clinic, more preclinical investigations are first n...

Evaluating Planning Metrics for Biology-Guided Radiation Therapy (BgRT)

Authors: Emily Hansen, Jay Mistry, Alois M. Ndlovu, Niara Rowe, Roland Teboh

Affiliation: Hackensack University Medical Center

Abstract Preview: Purpose: SCINTIX Biology-guided radiotherapy (BgRT) on the RefleXion X1 relies on a new planning system and advanced planning techniques. The first patient SCINTIX BgRT plans are compared to similar c...

Evaluating the Capabilities of Hypersight CBCT for Advanced Dual-Energy CBCT Imaging in Online Adaptive Radiotherapy

Authors: Yi-Fang Wang, Yading Yuan

Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology, Columbia University Irving Medical Center

Abstract Preview: Purpose: HyperSight, the latest CBCT technology from Varian Medical Systems, integrates rapid 6-second data acquisition with advanced iterative reconstruction and upgraded hardware. Previous studies h...

Evaluating the Efficacy and Efficiency of Spine Treatment Using Diagnostic CT

Authors: Sunil Mani, Ilakiya Raghavendiran, Vasanthan Sakthivel, Skanda Kabilan Swamy

Affiliation: Edmond Santa Fe High School, Edmnd Deer Creek High, Cancer Specialists of North Florida, Advanced Medical Physics

Abstract Preview: Purpose: Purpose/Objective(s): To evaluate and validate the dose calculation and delivery accuracy for patients planned using diagnostic CT
Methods: A total of forty-two patients with palliative sp...

Evaluating the Readiness for Ultra-Hypofractionated Prostate and Breast Radiotherapy in Sub-Saharan Africa: A Strategic Needs-Assessment of Six Leading African Institutions

Authors: Samuel O. Adeneye, Victoria Susan Ainsworth, Azeezat Ajose, Stephen M. Avery, Munir Awol, Kavuma Awusi, Onyinye Balogun, Rohini Bhatia, Frank Chinegwundoh, Jumaa Dachi Kisukari, Curtiland Deville, Katy Graef, Yao Hao, M. Saiful Huq, Luca Incrocci, Adedayo O. Joseph, Solomon Kibudde, Joerg Lehmann, Heng Li, Abba Mallum, Thokozani Mkhize, Twalib Ngoma, Wilfred Ngwa, Christopher F. Njeh, Janine Simons, William Swanson, Maureen Bilinga Tendwa, Joseph Weygand, Krishni Wijesooriya

Affiliation: Uganda Cancer Institute, Johns Hopkins University, BIO Ventures for Global Health, Weill Cornell Medicine, Washington University School of Medicine, South Africa Health Product Regulatory Authority, University of Pennsylvania, University of Massachusetts Lowell, NSIA-LUTH Cancer Center, University of Lagos, Indiana University School of Medicine, Department of Radiation Oncology, Erasmus Medical Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, Addis Ababa University, Ocean Road Cancer Institute, Emory University, Barts Health NHS Trust, Inkosi Albert Luthuli Central Hospital, Lagos University Teaching Hospital, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, University of Virginia School of Medicine, University of Newcastle

Abstract Preview: Purpose: Sub-Saharan Africa continues to face a critical shortage in radiotherapy resources, exacerbating the region’s growing cancer burden. One potential strategy that can partially offset this prob...

Evaluation of Hypersight CBCT Scanning Techniques for Motion Management in Online Adaptive Radiotherapy: A Comparative Study of Slow, Fast, and Averaged Scans

Authors: Fan Liu, Adam C. Riegel, Yi-Fang Wang

Affiliation: Columbia University Irving Medical Center

Abstract Preview: Purpose: HyperSight, Varian Medical Systems' latest CBCT technology, integrates rapid 6-second data acquisition with advanced iterative reconstruction, enabling precise real-time contouring and dose c...

Evaluation of Potential Dosimetric Risks from Intra-Fractional Motion in Single-Isocenter Stereotactic Radiosurgery

Authors: Brian D. Casto, Mathew Y Kang, Lichung Ku, Samuel J Wang, Joseph B. Ying, Walker Ray Zimmerman

Affiliation: Salem Health Cancer Center, Salem Health

Abstract Preview: Purpose: Varian HyperArc is an advanced radiotherapy module designed to efficiently deliver high-quality multi-target stereotactic radiosurgery (SRS) treatment plans on Varian linacs. However, the int...

Evaluation of Treatment Delivery Efficiency and Workflow Optimization in Prostate Stereotactic Body Radiation Therapy: A Comparative Study of C-Arm and O-Ring Linear Accelerators

Authors: Yijian Cao, Jenghwa Chang, Lyu Huang

Affiliation: Northwell, Hofstra University Medical Physics Program

Abstract Preview: Purpose: This study evaluates the treatment delivery efficiency and workflow of two advanced linear accelerator systems—Varian’s TrueBeam (C-arm) and Halcyon (O-ring)—for prostate Stereotactic Body Ra...

Evaluation on the Newest Automatic Isocenter Placement Function in ZAP-X Advanced TPS

Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang

Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center

Abstract Preview: Purpose: In August 2024, ZAP-X introduced automatic placement for isocenters in a DP-1010 upgrade for treatment planning. In this study, plans made by automatic placed isocenters are compared to those...

FMEA for Direct to Unit Adaptive Radiotherapy

Authors: Haleem Azmy, Robbie Beckert, Farnoush Forghani, Dean Hobbis, Dan Hong, Hyun Kim, Eric Laugeman, Silpa Raju-Salicki, Domenic Sievert

Affiliation: Washington University in St. Louis School of Medicine, WashU Medicine, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine in St. Louis, Washington University School of Medicine, Wash U Medicine, Washington University in St. Louis

Abstract Preview: Purpose: A novel radiation therapy (RT) workflow has recently emerged with the advent of online adaptive RT systems, direct-to-unit (DTU). DTU utilizes online adaptive platforms (MR and CT based) to o...

Feasibility Study of Deep Learning-Based MRI-to-PET Generation for Rectal Cancer: Overall Survival Prediction and Pathological Complete Response Assessment

Authors: Weigang Hu, Zhenhao Li, Jiazhou Wang, Xiaojie Yin, Zhen Zhang

Affiliation: Fudan University Shanghai Cancer Center

Abstract Preview: Purpose:
This study aims to develop and validate a novel deep learning method to generate synthetic PET images for rectal cancer from MRI data. By incorporating metabolic information from the synth...

Feasibility and Dosimetric Impact of Intensity-Modulated Radiotherapy for Cervical Cancer Patients in Nepal: A Retrospective Analysis

Authors: Daniela Branco, John M Bryant, Surendra Bahadur Chand, Pratiksha Shahi, Joseph Weygand

Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, B.P. Koirala Memorial Cancer Hospital, , B.P Koirala Memorial Cancer Hospital, University of California San Diego / California Protons, Department of Radiation Oncology, Moffitt Cancer Center

Abstract Preview: Purpose:
Cervical cancer remains a significant health burden in Nepal, with 2169 new cases and 1313 deaths recorded in 2022. This study evaluates the feasibility of implementing step-and-shoot IMRT...

First in-Vivo Application of a Novel Precision Small Animal Irradiation Platform with Proton IMPT Delivery and Advanced on-Board Image-Guidance

Authors: Niels Bassler, Jonathan Bortfeldt, Davide Boscaini, Francesco Evangelista, Guyue Hu, Ze Huang, Margarita Kozak, Julie Lascaud, Giulio Lovatti, Eero LÜnnqvist, Jasper Nijkamp, Munetaka Nitta, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Babak Sharifi, Brita Singers Sørensen, Peter Thirolf

Affiliation: Department of Medical Physics, Ludwig-Maximilians-Universität Mßnchen (LMU Munich), Ludwig-Maximilians Universität, Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) Mßnchen, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital

Abstract Preview: Purpose: To perform the first in vivo application of a novel small animal radiation research platform combining on-board image-guidance with multi-field intensity modulated spot scanning delivery [1] ...

Foundation Model-Augmented Learning for Automatic Delineation in Precision Radiotherapy

Authors: Xianjin Dai, PhD, Michael Gensheimer, Praveenbalaji Rajendran, Lei Xing, Yong Yang

Affiliation: Department of Radiation Oncology, Stanford University, Massachusetts General Hospital, Harvard Medical School

Abstract Preview: Purpose: Recent advances in the automatic delineation of radiotherapy treatment targets, which incorporate linguistic clinical data extracted by large language models (LLMs) into traditional visual-on...

From Supine to Upright: A Geometric Shift in Perspective

Authors: Ben Durkee, Renata Farrell, Carri K. Glide-Hurst, Colin Harari, Alex Singleton Kuo, Chase Ruff, Jordan M. Slagowski, Yuhao Yan

Affiliation: University of Wisconsin, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Advances in upright CT and patient positioning system now enables high quality daily CT imaging and treatment delivery in the upright position, providing benefits including reduced internal m...

HypersightÂŽ Offline Adaptive Workflow

Authors: Doris Dimitriadis/Dimitriadou, Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Noor Mail, Adam Olson, Tyler Wilhite

Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, UPMC

Abstract Preview: Purpose: The goal of the HyperSightÂŽ offline adaptive-workflow is to create a methodical approach to adaptive-radiotherapy (ART) that considers modifications in patient setup and anatomy. Through effi...

Impact of Translucent Sheet Bolus and Melanin Concentration on Recorded Optical Signal during Cherenkov Imaging in External Beam Radiation Therapy

Authors: Jacqueline M. Andreozzi, Savannah Decker, Diego Hernandez, Iman R. Washington

Affiliation: UC San Diego, Department of Radiation Oncology, Moffitt Cancer Center, University of South Florida, Moffitt Cancer Center

Abstract Preview: Purpose: Recent advances in external beam radiation therapy have begun to explore the utility of Cherenkov radiation imaging as a beam delivery visualization tool. When sheet bolus is used during trea...

In-Silico Clinical Trials Enabled By Digital Twin Approach Can Accurately and Prospectively Predict Outcomes of Clinical Trials Combining Radiation and Systemic Therapy

Authors: Clemens Grassberger, David (Bo) McClatchy, Harald Paganetti

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Massachusetts General Hospital

Abstract Preview: Purpose: While randomized controlled trials (RCTs) are the gold standard for demonstrating efficacy, nearly 50% of late-stage clinical trials fail to meet their endpoint. Tools to study the design of ...

Introducing Medical Physics to Undergraduate Students: Willis Knighton Cancer Center and Louisiana Tech University's Unique Collaborative Education Effort

Authors: Pedro Derosa, Joseph P. Dugas, Neven Simicevic, Hsinshun Terry Wu

Affiliation: Louisiana Tech Univeristy, Willis Knighton Cancer Center, Willis-Knighton Cancer Center

Abstract Preview: Purpose: To design and implement a collaborative educational effort between a regional university and unaffiliated cancer center introducing medical physics to an unaware undergraduate population at a...

Investigating the Multimodal Fusion Techniques to Improve Prediction Accuracy of Biochemical Recurrence of Prostate Cancer

Authors: Clint Bahler, Ruchika Reddy Chimmula, Harrison Louis Love, Oluwaseyi Oderinde, Courtney Yong

Affiliation: Purdue University, Department of Urology, Indiana University School of Medicine, Advanced Molecular Imaging in Radiotherapy (AdMIRe) Research Laboratory, School of Health Sciences, Purdue University

Abstract Preview: Purpose: Prostate cancer (PCa) is a common malignancy in men, and predicting biochemical recurrence (BCR) is crucial for guiding treatment decisions. Integrating multimodal data, including clinical, i...

Investigation of Treatment Planning System (TPS) Algorithms for Helical Tomotherapy Total Body Irradiation (TBI)

Authors: John T Barrett, Chulhaeng Huh, Farshad Mostafaei, Michelle Rocque, Austin Sanders

Affiliation: Department of Radiation Oncology, Medical College of Georgia, Augusta University, Department of Radiation Oncology, Augusta University, Georgia Radiation Therapy Center, Wellstar-MCG Health

Abstract Preview: Purpose: This study involved the use of Accuray’s TPS (Precision) and RayStation TPS for planning TBI treatments. TBI was delivered using Accuray’s Radixact machine, and dose calculation algorithm, do...

Leveraging Codex-Based Spatial Profiling of the Tumor Microenvironment in Concurrent Radiation Therapy and Immunotherapy

Authors: Todd A Aguilera, Bassel Dawod, Sebastian Diegeler, Eslam Elghonaimy, Purva Gopal, Jiaqi Liu, Hao Peng, Arely Perez Rodriguez, Nina N. Sanford, Robert Timmerman, Megan B Wachsmann, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center

Abstract Preview: Purpose: This study pioneers the integration of CODEX (co-detection by indexing)-based spatial profiling and advanced computational techniques to investigate the tumor immune microenvironment (TIME) i...

Machine Learning Model for Early Prediction of Chemoradiotherapy Response in Oropharyngeal Cancer Patients

Authors: Waleed Mutlaq Almutairi, Ke Colin Huang, Vishwas Mukundan, Christopher F. Njeh, Oluwaseyi Oderinde, Yong Yue

Affiliation: Purdue University, Indiana University School of Medicine, Department of Radiation Oncology, Advanced Molecular Imaging in Radiotherapy (AdMIRe) Research Laboratory, Purdue University, West Lafayette, Indiana, USA

Abstract Preview: Purpose:
This study aimed to develop a machine learning (ML) model for early prediction of chemoradiotherapy (CRT) response in order to enhance personalized treatment selection for oral or orophary...

Medical Physics Training Program, Staff Retention, and Service Improvement Strategy in a Regional Radiotherapy Centre

Authors: Dilli Banjade, Ajeet Mishra, Shiaw Juen (Eugene) Tan

Affiliation: District Radiation Oncology Service WNW Health

Abstract Preview: Purpose: A shortage of qualified Radiation Oncology Medical Physicists (ROMPs) poses a critical challenge to providing advanced treatments in regional Australia. Training and retaining medical physici...

Muilt-Instance Learning Model with 2D and 3D Features Representation and Transformer-Based Prediction for FDG PET Tumor Chemoradiation Response of La-NSCLC

Authors: Stephen R. Bowen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Jiajie Wang, Shouyi Wang, Faisal Yaseen, Han Zhou

Affiliation: Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Fred Hutchinson Cancer Center, University of Texas at Arlington

Abstract Preview: Purpose: Predicting the effects of the spatial-temporal tumor response to chemoradiation can assist in adjusting radiation dose and support clinical decision-making in radiotherapy. A multi-instance l...

Multidisciplinary Collaboration in Medical Physics-a Need for Namibia's Healthcare System.

Authors: Kaino Haipinge, Festus Laban, Wilfred Midzi, Boas J Nikanor, Monika Sakaria, Vera Uushona

Affiliation: Ministry of Health and Social Services, MATCON BASED SOLUTION, Ministry of Health And Social Services, School of Medicine, University of Namibia

Abstract Preview: Purpose: Medical Physics in namibia is emerging as a multidisciplinary career, with efforts to raise awareness about the role of medical physics in radiation safety, treatment and protection. The prof...

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Authors: Houssam Abou Mourad, Christopher Ackerman, Stephen Adler, Kirk Aduddell, Muhammad K. Afghan, Hamid G. Aghdam, Diego Aguilar, Kang-Hyun Ahn, Francis Ai, Hua Ai, Ray Anthony Aikens, Manik Aima, Victoria Ainsworth, Erfan Akbari, Blessing Akinro, Rani Al-Senan, Khalid Alabbasi, Sam Alam, Daniel Alexander, Mohammed H. Aljallad, Mazin T. Alkhafaji, Ahmad K. Alkhatib, Scott J. Alleman, James Logan Allen, Ibtisam Almajnooni, Tiba Alnaqshabandi, Murat Alp, Stephen J. Amadon, Riska Amilia, Ala Amini, Shiho Amster, Mason R. Anders, Erin Angel, Ledi Anggara, John A. Antolak, Debora Antonio, Felicity Appiah, Haiqa Arain, Lahcen Arhjoul, Ali V. Aritkan, Muhammad Arshad, Mark E. Artz, Nathan S. Artz, Frank A Ascoli, John R. Ashburn, Benjamin Astarita, Masakazu Atsumi, Rex G. Ayers, Tara M. Bachman, Nina L. Bahar, Bing Bai, Michael J. Bailey, Chris Baird, Mohammad Bakhtiari, Andrew J. Ballesio, Isabel Balvoa, Qinan Bao, Jeffrey J. Barbarits, Joseph Barbiere, Philip C. Bardos, Gary T. Barnes, John C. Barrett, Divya Bartley, Steven J. Bartolac, Robert Barton, Christopher P. Bass, Loni Bates, Alan Baydush, John E. Bayouth, Stephen Beach, Kevin Beaudette, Kaelyn Becker, Natalie A. Beckmann, Colleen Beer, Sepideh Behinaein, Jake M. Bell, David M. Bellezza, Maria R. Bellon, Ahmed Benelfassi, Stephanie Louise Bennett, Todd Bernath, Kate Bevins, Nicholas B. Bevins, Brian J. Bismack, David Blaich, Anthony P. Blatnica, Joseph W. Blickenstaff, Steven Blum, Maggie Bobbett, Dayna Bodensteiner, Daniel Boedeker, Robert C. Boggs, Jason D. Bond, Sjirk N. Boon, Jennifer M. Borsavage, Ryan J. Bosca-Harasim, Ryan J. Bosca-Harasim, Satya R. Bose, Todd Bossenberger, Cristina Boswell, Djamal Boukerroui, Christopher M. Bowen, Aaron Brammer, Rich Brancaleoone, Eric Brass, Luis Bravo, William Breeden, Christina Breeze, Eric E. Brost, Justin L. Brown, Karen L. Brown, Marissa Brown, Norman Lee Brown, Payton Brown, Patrick V. Brunick, Ryan Brunkhorst, Gwendolyn P. Brunner, Camelia E. Bunaciu, Maria Bunta, Olwen Burton, Karim Butalag, Priscilla F. Butler, Angela Cagwin, Jeffrey L. Campbell, Warren G. Campbell, Tyler Cantrell, Xu Cao, Yanan Cao, Peter F. Caracappa, Amanda M. Caringi, Joe Caron, Joshua Carter, Kenneth W. Cashon, Sarah Castillo, Everett Cavanaugh, Suran Chae, Abhi Chakrabarti, PhD, Philip Chan, Jina Chang, Sha X. Chang, Youssef M. Charara, Pierre E. Charpentier, Priyanka Chaudhary, Senthamil Selvan Chelliah, Chen Chen, Doris Chen, Kuan Ling Chen, Max Chen, Mingyue Chen, Mu Chen, Xinan Chen, Yie Chen, Yong Chen, Caroline Cheney, Shyh-Shi R. Chern, Stephen Thomas Chesser, Kin Man Cheung, Pai-Chun Melinda Chi, Yuwei Chi, Omar Chibani, Hung Ching, Gwi Ae Cho, Jongmin Cho, David Choi, Wing Yan Choi, Nitish Chopra, Daniel Christ, Olav I. Christianson, Emmanuel Christodoulou, Heeteak Chung, Sophia Claudio, Arely Clavel, William J. Clouse, Gilad Cohen, Michael S. Cohen, Vladimir Collantes, Jason Collier, Jacob Collins, Daria C. Comsa, Charles Conduah, Virgil N. Cooper, Anita M. Corrao, Frank D. Corwin, Mihaela Cosma, Ben Coull-Neveu, Mary K. Cox, Daniel F. Craft, Steven D. Crawford, Troy M. Crawford, Charles E. Creagh, Beatrice Croteau, Camille Crumbley, Wilbert F. Cruz, Guoqiang Cui, J. Adam M. Cunha, Scott Cupp, Bruce H. Curran, Jordan McCauley Cutsinger, Alita D Almeida, Harold DSouza, Nana Dabo-Akoteng, Robert Dahl, Shaun W. Dahl, Ghayath Dakkouri, Malek Daneshvarnezhad, Mylinh Dang, Matt Daniels, George M. Daskalov, David A. Davenport, Amanda Davidek, Scott E. Davidson, Maria De Ornelas, Dylan A. DeAngelis, Mike Deady, Daniel Dean, Savannah Decker, Savannah Decker, Michael Delafuente, Omer Demirkaya, Logan Dempsey, Marc Dennis, Viv Dennis, Dana Derby, Garron A. Deshazer, Veronique Destombes, Ajaya K. Devabhaktuni, Suneetha Devpura, James A. Deye, Shalmali Dharmadhikari, Dominic J. DiCostanzo, Richard V. DiPietro, Emily Diller, Lei Ding, Nayha V. Dixit, Charles Dodge, David N. Dodoo Amoo, Shana Donchatz, Lei Dong, Elangovan Doraisamy, Jennifer E. Dorand, Sarah Driver, Jiayi Du, Michael Duax, Ibrahim M. Duhaini, Ibrahim Duhaini, Kristen Duke, Richard Dunia, Leon Dunn, Shannon R. Durfee, Brittany Earl, Behzad Ebrahimi, Colton Eckert, Hisham Elasmar, John G. Eley, Abdelhamid Elfaham, David C. Ellerbusch, Scott J. Emerson, Sara Endo, David Erickson, Freddy Escorcia, Caroline Esposito, Patrice Essien, Adam Evearitt, Benjamin Fahimian, Liliosa C. Fajardo, Kevin Fallon, Guoqing Fan, Jiahua Fan, Mingdong Fan, Pei Fan, Bing Fang, Jian Fang, Yile Fang, Marc A. Felice, Ye Feng, Michele Sutton Ferenci, Philippe Feru, Jade Alecia Fischer, Aaron Fishbein, Caitlyn M. Fitzherbert, Damian Fondevila, Grant Fong, Robert Wesley Foster, Luke Fourie, Jeffrey Brian Fowlkes, Alexandre Franca Velo, D. Jay Freedman, Ronald W. Frick, Jie Fu, Samuel Fulton, Kamalakar Gaddam, Justin D. Gagneur, Mariana Gallo, Mariana Gallo, David Gammel, Robert G. Gandy, Junfang Gao, Yiming Gao, Victor L. Garcia, Michael Garcia-Alcoser, Jeffrey Garrett, Steven Anthony Gasiecki, Keith Gatermann, Avinash Gautam, Bhoj Gautam, Olivier Gayou, Andrew J. Gearhart, Paul B. Geis, Renil B. George, David P. Gierga, Robert Gilliam, James Giltz, Eric L. Gingold, Frederic Girard, Garth Gladfelder, Sharon Glaze, Brendan K. Glennon, Steven P. Glennon, Guy Godwin, David Lloyd Goff, Lisa M. Goggin, Daniel Goldberg-Zimring, Edward Joseph Goldschmidt, Ehsan Golkar, Angel Gomez, Jason Gong, Manish K. Goyal, Frank Graeff, Royce L. Gragg, Jonathan Gray, Alexander D. Green, Olga L. Green, Andrew Christopher Greene, Travis Greene, Jared Grice, Kevin T. Grizzard, Suveena Guglani, Jeffrey B. Guild, Patrick P. Guo, Sandesh Gupta, Megan Gute, Jonathan Ha, Rachael L. Hachadorian, Christopher Haddad, Lubomir Hadjiiski, Scott W. Hadley, Tomoe Hagio, Kelsey Hall, Logan P. Hall, Klaus A. Hamacher, Amineh Hamad Khatib, Amineh O. Hamad Khatib, Brian R. Hames, Carnell Hampton, Samuel S. Hancock, Robyn S. Handschuh, Jeremy Hansen, Paul Harden, Joseph Harms, Daniel P. Harrington, Carley Harris, Jamie Marie Harris, Jennifer Hart, Richard P. Harvey, Jeremy Hawk, Naoki Hayashi, Maria Laura Haye, Katherine Hazelwood, David Hearshen, Bret H. Heintz, Adam Henry, Frank William Hensley, Michael Chris Hermansen, Marissa Hernandez, Nadia Hernandez, Dayadna Hernandez Perez, Sarah Hetherington, Emily Hewson, Maynard High, Brian P. Hill, Charles B. Hill, Yunsil Ho, Simeon Hodges, David M. Hoeprich, Michael N. Hoff, Robert F. Hoffman, Russell Holden, Clay Holdsworth, Scott Hollingsworth, John R. Holmes, Steve Holmes, Neal S. Holter, Thomas M. Holtschneider, Amirul Hoque, Sabbir Hossain, Tyler S. Howlin, Andrew Robert Hoy, An Ting Hsia, Hao-Yun Hsu, David Hu, Tom C. Hu, Yu-Chi Hu, Long Huang, Mi Huang, Joshua Hubbell, Michael J. Huberts, Julie C. Hudson, Geoffrey Hugo, Donglai Huo, Justin D. Hurley, Martina H. Hurwitz, Mohammad NASEEM Hussain, Andrew Hwang, Ui-Jung Hwang, Joe Ianni, Geoffrey Ibbott, Khalil Ibrahim, Ileana Iftimia, Mohammad Islam, Oleksandra Ivashchenko, Keyvan Jabbari, Joshua Jackson, Joshua Jackson, Ferenc Jacso, Mary Ellen Jafari, Karim Jaffer, Amit Jain, Ngoneh Jallow, Sachin R. Jambawalikar, Joshua A. James, Sunyoung Jang, Desiree Jangha, Tomaj Javidtash, Jun-Hsuang Jen, Peter Jenkins, Todd P. Jenkins, Andrew R. Jensen, Mads Lykke Jensen, Hosang Jin, Bowen Jing, Danielle Marie Johnson, Joshua D. Johnson, Holly Johnston, Kevin Jones, Badal R. Juneja, Nikhil Sriram Kabilan, Robert Kaderka, Jaclyn Kain, Faraz Kalantari, Maduka M. Kaluarachchi, Ali Kamen, Amrit Kaphle, Alireza Kassaee, Saravjeet Kaur, Vaiva Kaveckyte, Linda A. Kelley, Katelyn Kelly, Kathryn Elise Bales Kelly, Delsin B. Khan, Om Khanal, Maksud Khatri, William Steadman Kiger, Bryan Kim, Jong Oh Kim, Sangroh Kim, Sophia Kim, Brian W. King, Erica Kinsey, Assen S. Kirov, Marc T. Kleiman, Matic Knap, Robert J. Kobistek, Inger-Karine Kolkman-Deurloo, Erika Kathryn Kollitz, Dramane Konate, Xiang Kong, Walter Kopecky, Sandra Kos, Nataliya Kovalchuk, Shane Krafft, James A. Kraus, Robert Krauss, Deae-eddine Krim, Serguei Kriminski, Kerry T. Krugh, Lichung Ku, Esra Kucukmokroc, Randi Kudner, Andrew T. Kuhls-Gilcrist, Antti Juhani Kulmala, Akila D. Kumarasiri, Zacariah E. Labby, Taylor Lackey, Edcer Jerecho Laguda, Thang Lam, Michael A. S. Lamba, Kara Lambson, Laurel Zenaida Larramendi, Andy D. Lau, Wolfram Laub, Tyler Laugh, Robert P. Laureckas, Donald Laury, Patricia Lavey, Ashlie Laydon, Adam LeVay, Brandon Lee, Brian Lee, Dong-Chang Lee, Ji Hyun Lee, Jui-Min Lee, Bryan Lemieux, Matthew Lesher, Nicole Leslie, Etienne Lessard, Trish Lewis, Alan Li, Alexander N. Li, Hui Li, Jenny Li, Jiaxin Li, Qiongge Li, Taoran Li, Xiang Li, Yanlong Li, Zisheng Li, Xing Liang, Yun Liang, Chien-Yi Liao, Karisa Liaw, Sung-Yen Lin, Tiffany Lin, Holly M. Lincoln, Lin Ling, Chang Liu, Shaohua Liu, Yu Liu, Chih-Ming Mark Lo, Eric Lobb, Dilson Lobo, Virginia L. Lockamy, Lauren C. Long, Nelia S. Long, Troy Long, Michele Loscocco, Thomas Lowinger, Cynthia Lu, Minghui Lu, Winnie Lu, Yonggang Lu, Jianqiao Luo, Pei-Chin Luo, Xuhan Luo, Jan Luse, Daniel A. Lutterman, Dang Hoang Oanh Luu, Yulia Lyatskaya, Trina Lynd, Morgan Cervo Lyon, Chi Ma, Jingfei Ma, Tianjun Ma, Laurie Madden, Gregory E. Madison, Kurt Maffei, Michael J. Maffett, Nyasha G. Maforo, Dennise Magill, Emma Magness, Alphonso W. Magri, Dennis Mah, Usman Mahmood, Rebecca N. Mahon, Courage Mahuvava, Andrew D. Maidment, Gerassimos M. Makrigiorgos, Harish K. Malhotra, Kate Mallory, P. Scott Mange, Vivek Maradia, Jacob Marasco, Camilla Marino, Loren R. Marous, Wagner Marques, Craig M. Marsden, Edward I. Marshall, Jonathan Marshall, Caroline Martel, Colin Martin, Alejandro Martinez, Jeffrey P. Masten, Richard Mathew, Bobby Mathews, Anetia S. Matthews Jackson, Matthew R. Maynard, Joel R. McAllister, Rafe McBeth, James A. McCulloch, Kiernan T. McCullough, Keelin McGee, Kiaran P. McGee, Brian M. McGill, Christopher M. McGuinness, Robert McKoy, Steven M. McQuiggan, Lacey Medlock, Chirag D. Mehta, Nancy Meiler, Robert Meiler, Matthew A. Meineke, Caroline Melancon, Daniel S. Meleason, Carolyn Meltzer, Chunhua Men, Stephanie Merkl, Michael Merrick, Keith A. Michel, Georgeta Mihai, Ana Mihail, Devin A. Miles, Edward J. Miller, Elizabeth A. Miller, Ronaldo Minniti, Linda Minor, Filmon Misgina, Ajeet Kumar Mishra, Chad Mitchell, Drew P. Mitchell, Gregory S. Mitchell, Jessica Mitchell, Jacqueline Moga, Uwe Mollenhauer, Julien-Fabrice Ngoune Momo, Emi Mondragon, Nicholas Mongillo, Victor J. Montemayor, Scott Montgomery, Diego Luis Montufar Hidalgo, Mohammadamin Moradi, Serban Morcovescu, Jill Anna Moreau, Terrance Moretti, Toby Morris, Courtney K. Morrison, Alexander Albert Morrow, Jill Moton, Jonathon Mueller, Reshma Munbodh, Daniel W. Mundy, Daniela Murgulet, Scott A. Murphy, Benjamin C. Musall, Jana E. Musgrove, Samantha Musial, Yong Hum Na, Joel Nace, Paul Naine, Justin Napolitano, Vrinda Narayana, Ganesh Narayanasamy, Moulay Ali Nassiri, Muhammad Naveed, Richard D. Nawfel, Ritish Nedunoori, Aaron Nelson, Kristin J. Nelson, Aaron Nelson, MD, Neerajan Nepal, Emily Neubauer Sugar, Shree Neupane, David Newey, Mark Newpower, Susan Ng, Bau H. Nguyen, Daniel J. Nicewonger, Xingyu Nie, Ethan Nikolau, Kevin D. Nitzling, Kai Niu, John M. Noll, Prashanth K. Nookala, Khalid Noori, James T. Norweck, Hamidreza Nourzadeh, Jessica L. Nute, Sebastiaan Nysten, Kevin OGrady, Ceferino Obcemea, Keith Ober, Jacqueline Ogburn, Timilehin Ogunbeku, Mina Okello, Brian Olson, Martin Keane Ongeti, Savannah Orrill, Joseph Ott, Bahadir Ozus, Jan Pachon, Alexis Paige-Glenn, Jason Paisley, Farideh Pak, Randahl C. Palmer, Kiran Pant, Virginia Pappas, Abby Pardes, So-Yeon Park, Alexis Parker, Karla Parker, Homayon Parsai, Tommy O. Parsons, Pankaj Patel, Amy Patrick, Johnlly G. Pattaserial, Lindsey M. Patton, Taylor J. Patton, Nava R. Paudel, Timothy John Paul, Colin Paulbeck, Olga V. Pen, Cheng Peng, Yuanlin Peng, Carmelo Perez, Dominik PeruĹĄko, Alexander Pevsner, Douglas Pfeiffer, Melanie Piantino, Daniel Piatigorski, Rajesh Pidikiti, Natalie Piechowska, Greg Pierce, Tina Pike, Donika Plyku, Robert Pohlman, Mariela Adelaida Porras-Chaverri, Subechhya Pradhan, Guillem Pratx, Chris Proctor, Alexander Pryanichnikov, Diane Pugel, Yue Qiu, Adam C. Quinton, Todd Racine, Andrea Radine, Dustin K. Ragan, Balasubramanian Rajagopalan, Kishore Rajendran, Eric V. Ramirez, Mehdi Ramshad, Vijay K. Rana, Brianne Raulston, Amy K. Readshaw, Hailey Reaux, Ian Reineck, Xuemin Ren, Meral L. Reyhan, Davenport Ria, Matthew J. Riblett, Kenneth M. Richardson, Rebecca F Richardson, Matthew Richeson, Ashlyn Rickard, Adam Riegel, Lynn N. Rill, Miguel A. Rios, E. Russell Ritenour, Scott P. Robertson, Marthony L. Robins, Rebecca Robinson Rey, Steve Rodney, Priscila Rodrigues, Edgardo Rodriguez, Tino Romaguera, Emilie Roncali, Joseph E. Roring, Alison R. Roth, Lawrence N. Rothenberg, Nick Rothwein, Kricia Emilia Ruano Espinoza, Damian DG Rudder, Donald R. Ruegsegger, Erwin W. Ruff, Brandon J. Russell, Frederick Rustad, Narayan Sahoo, Jonathan H. Saleeby, Habeeb H. Saleh, Flavio Salinas Aranda, Steffen Sammet, Daniel Sandoval, Aman Sangal, Joseph P. Santoro, MaĂ­ra Santos, Alexis Marie Sanwick, Milind Sardesai, Vikren Sarkar, Duminda Satharasinghe, Jessica L. Saunders, Carmen Sawyers, Sarah B. Scarboro, James Scheuermann, Colleen G. Schinkel, Dale Schippers, Joshua William Schlegel, David J. Schlesinger, Charles Ross Schmidtlein, Erich Schmitz, Jose Schneider, Erich A. Schnell, Lisa Schober, Leah Schubert, Michelle L. Schwer, James Seekamp, Jennifer Seger-Paisley, J. Anthony Seibert, Balaji Selvaraj, Raj N. Selvaraj, Meredith A. Semon-Pomposelli, Lasitha Senadheera, Naima Senhou, Christopher F. Serago, Hananiel Setiawan, Shakil B. Shafique, Aarti Shah, Hina Shah, Alok Shankar, Ryan Shanks, Kritika Sharma, Sunil K. Sharma, Jennifer M. Shealy, Ron Sheen, Gina L. Shelton, Mohammad Ullah Shemanto, Zion Sheng, Andrew J. Shepard, Justin R. Sherman, Kaizhong Shi, Xiaolin Shi, J. Allen Shih, Taciana Soares Shiue, Deborah J. Shumaker, Noah Silverberg, Ramon Alfredo C. Siochi, Amogh Sirniirkar, Marlene Skopec, Michael G. Skowronski, Dana Smetherman, Erika Smith, Eileen Sneeden, Jesse Snyder, James C. So, Emilie Soisson, Nima Soltani, Kwang Hyun Song, Liang Song, Xiaoling Song, Jigar B. Soni, Yashvant C. Soni, Jagadeesh R. Sonnad, Michael A. Speidel, Michael P. Speiser, James D. Speitel, Tanya Spellman, Joseph Patrick Speth, Daniel J. Spitznagel, Sara T. St. James, Alexander Stanforth, George Starkschall, James Stebelton, James P. Steinman, Jonathan M. Stenbeck, Robin L. Stern, Patrick D. Stevens, Erika Stewart, Gary Stinnett, Sarah A. Strand, Keith J. Strauss, Kristen Stryker, Edward Sudentas, Kevinraj N. Sukumar, Orhan H. Suleiman, John L. Sullivan, Paul Robert Sullivan, Mei Sun, Peng Sun, Kumari Sunidhi, Jacob Sunnerberg, Elizabeth A. Swanson, William J. Swanson, Larry E. Sweeney, Sean Swiedom, Gregory Szalkowski, Katsuyuki Taguchi, MohammadAli Tajik-Mansoury, Reza Taleei, Derek Tang, Shengzhang Tang, Mahin Tariq, Jason S. Tavel, Neelima Tellapragada, Alexandra Tellez, Dawn Tellez, Juan Manuel Tellez, Xiaokun Teng, James A. Terry, Biniam Tesfamicael, Confex Test, Aapm Tester, Contex Tester, Namita Thakur, David J. Theel, Kathleen D. Thomas, Emily A. Thompson, Stephen K. Thompson, Daniela Thorwarth, Kevin Tierney, Anders Tingberg, Ragu S. Tirukonda, Robert A. Tokarz, Robert J. Tokarz, Naresh B. Tolani, Brian Tom, Shidong Tong, Ebrahim Torangan, Martin Tornai, Diana Tovmasian, Trung Tran, Bryan Traughber, Samuel Trichter, Sugata Tripathi, Petra Trnkova, Panagiotis Tsiamas, Ryan Tsiao, Haifeng Tu, Philip N Tubiolo, Jeff D. Turley, Adam Turner, PhD, DABR, Conner Ubert, Chibueze Zimuzo Uche, Vincent M. Ulizio, Gnanaprakasam Vadivelu, Hema Vaithianathan, Sunil Valaparla, Fabiola Vallejo CastaĂąeda, Liesbeth Vancoillie, Matt Vanderhoek, Caroline Vanderstraeten, Nancy J. Vazquez, Linda A. Veldkamp, Trevor L. Vent, Anthony M. Ventura, Keith Ver Steeg, Irina Vergalasova, CHENG WANG, Christopher Waite-Jones, Matthew C. Walb, Reuben Waldron, Arlie Vester Walker, Jim Walsh, Alisa I. Walz-Flannigan, Cheng Wang, Helen H. Wang, Hui-Chuan Wang, Jiali Wang, Jian-xiong Wang, Kai Wang, Kyle Wang, Ning Wang, Yuntao Wang, Zhendong Wang, Zhixing Wang, Grace Ward, Sarah M. Way, Rachel L. Waymire, Melvin Weatherly, Charles Travis Webb, Lincoln J. Webb, Jia Wei, Wenbo Wei, Callie Weiant, Miriam S. Weiser, Eric M. Welch, Jered R Wells, Michelle C. Wells, S. Brock Westlund, Gerald A. White, John White, Darunee S. Whitt, David Wikler, Austin Wilkinson, Carly D. Williams, Mark Bennett Williams, Joshua M. Wilson, Keli C. Wilson, Nicholai Wingreen, Joseph Wishart, Alon Witztum, Katherine M. Woch Naheedy, Andy Wolf, Serkalem E. Wondimgezhu, Genevieve N. Wu, Wenhao Wu, Ye Wu, Yuxiang Xing, Li Xiong, Weijun Xiong, Xunyi Xu, Yan Xu, Tianyou Xue, Yanjie Xue, Girijesh K. Yadava, Derek Z. Yaldo, Kaiguo Yan, Yue Yan, Nathan E. Yanasak, Bowen Yang, Ray Yang, Xiaocheng Yang, Yun Yang, Yunze Yang, Bin Yao, Yuan (John) Yao, Anna N Yaroslavsky, Feng-Ju Yeh, Susanne Yerich, Michael V. Yester, Xiaofei Ying, Tekeste Yohannis, Tony Younes, Eyesha Younus, Jialu Yu, Justin Yu, Yan Yu, Pui Kuen Yuen, Joshua P. Yung, Steve Yuvan, Mehran Miron Zaini, Ramtin Zakikhani, Lee Anne Zarger, Merissa Zeman, Lisa Zent, Di Zhang, Dongqing Zhang, Hao Zhang, Jun Zhang, Lei Zhang, Lu Zhang, Maochen Zhang, Peng Zhang, Peng Zhang, Qingyun Zhang, Xin Zhang, Yi Zhang, Yinghui Zhang, Yongbin Zhang, Zhongwei Zhang, Bo Zhao, Xuandong Zhao, Yizhou Zhao, Weiping Zheng, Yi Zheng, Troy Zhou, Xiangzhi Zhou, Xiaohong Joe Zhou, Yuwei Zhou, Jin Zhu, Mingyao Zhu, Eric C. Zickgraf, John R. Zullo, Piotr Zygmanski, Leo van Battum

Affiliation: DTC Consultants, NL Health, Dartmouth Hitchcock Medical Center, ProCure Proton Therapy Center, Medical & Radiation Physics, Inc, Augusta University, Genesis Healthcare Partners, Michigan Medicine, Washington DC VA Medical Center, VA Medical Center, Mercy Southeast Hospital, Food And Drug Administration, University of Iowa, Advanced Radiation Physics Service, Inc, University of Pittsburgh, University of Wisconsin, Wellspan Health, Good Samaritan Hospital, Howard University Hospital, St. Mary's Memorial Health Center, Penn State Milton S. Hershey Med Ctr., New York Weill Cornell Medical Ctr, X-Ray Computations, Inc., US Navy, Penn State Health, Kelsey Seybold Clinic, Advocate Aurora, Fresno Cancer Center, Central Alabama Radiation Oncology, Riverside Methodist Hospital Ohio Health, Alliance Medical Physics, OCSRI, AAPM, University of Minnesota, University of Virginia Health System, PGIMER, Barrigel, Johns Hopkins Univ, Appex Physics Partners, BoxElder Research, University of Oklahoma Health Sciences Center, Sanford Roger Maris Cancer Center, Berkshire Medical Center, New York Weill Cornell Medicine, Mobimed Technologies, University of Chicago Medicine, Johns Hopkins Medicine, Maimonides Medical Center, Nuvance Health - Vassar Brothers, Crozer Keystone Health System, Karmanos/McLaren, Vanderbilt University, Panhandle Cancer Care Center, The University of Michigan, Piedmont Healthcare, Gamma Medical Physics LLC, Mississippi Baptist Medical Center, Astarita Associates Inc, Landauer Medical Physics, RPS Oncology, Zhejiang University, University of North Carolina School of Medicine, University of Kentucky HealthCare, Peninsula Regional Medical Center, Varian Advanced Oncology Solutions, New York Proton Center, Wake Forest University Medical Center, Rutgers Robert Wood Johnson Medical School, Tx Oncology, Lewis Hall Singletary Oncology Center (John D. Archbold Hospital), Medical Physics Services, University of New Mexico, UPMC Cancer Center, Medical Physics Solutions, LLC, ECU Health, Evercare Hospital Chattogram, Mercy Cancer Center, Sharp Grossmont Hospital, West Virginia University, Virginia Commonwealth University Medical Center, Thomas Jefferson University, Centennial Medical Physics, LLC, University of California, Davis, University of Miami, Varian, Inc., UAB Medical Center, Wellspan health, Cleveland Clinic Foundation, Procure Treatment Center, Retired FDA, Tufts Medical Center, Virginia Commonwealth University, Germantown Academy, Hartford Hospital, Cleveland Clinic Florida, Billings Clinic, Imalogix, University of Wisconsin - Madison, Dana Farber Cancer Institute, Massachusetts General Hospital, Johns Hopkins University, GenensisCare, VARIAN Siemens Healthineers, MedStar Washington Hospital, Illawarra Cancer Care Center, Duke Health, Corewell Health, Columbia University, Johns Hopkins, Baylor Scott & White Health, Ascension Saint Thomas Rutherford Hospital, Varian, a Siemens Healthineers company, Rabin Medical Center, Albany - Stratton VA, Florida Cancer Specialists at Tampa Cancer Center, Baylor St Lukes Medical Center, Baylor College of Medicine, Christiana Care Health System, West Physics, Mayo Clinic Arizona, Emory University, University of Pittsburgh Medical Center, Brigham and Women's Hospital, UCLA, CoxHealth, Starsino Medical Technologies Co Ltd, University of Utah Hospitals, Lahey Health Medical Center, Paul Scherrer Institute (PSI), Karmanos Cancer Institute, Radcom Associates, LLC, Ascension Wisconsin, The University of Alabama at Birmingham, Winter Park Cancer Center, Louisiana State University, UT Health San Antonio, Intermountain Health, Penn Medicine/Lancaster General Health, Elekta Xoft, University of KY HealthCare, Rutgers, Cancer Institute of New Jersey, Real Time Tomography LLC, Toronto Metropolitan University, UCSD, Dartmouth College, Ascension St. Thomas Rutherford hospital, City of Hope, Radiation Management Associates, Levine Cancer Institute, Atrium Health, Varian Medical Systems, Blount Memorial Hospital, Penn State University, Therapy Physics, Inc., Northwest Community Hospital, Duke University Medical Center, Advent Health, Miami Cancer Institute, Washington State Department of Health, Lantheus Medical Imaging, Chesapeake Potomac Regional Cancer Center, MRP Inc., University of Chicago, University of Tennessee Medical Center, Huntsman Cancer Institude, University of Utah, Oregon Health and Science University, Hutchinson Regional Medical Center, Winchester Medical Center, WellSpring Oncology, Medical School of East Carolina Univ, Weill Cornell Medical Center, UPMC Hillman Cancer Centers, Springfield Clinic, CaliberMRI, Inc., Prisma Health, Helen F. Graham Cancer Center, ChristianaCare, Upstate Medical Physics, PC, Loma Linda University Medical Center, Radpocket LLC, RayzeBio, St. Peter's Health Partners, MJS Medical Physics Inc., UCHealth, Astarita Associates, Image X Institute, School of Health Sciences, University of Sydney, Oregon Urology Institute, Seoul National University Hospital, GenesisCare, Reid Health, National Institutes of Health (NIH), Bayhealth Medical Center, Albany Medical College, Advocate Radiation Oncology, Rush, Krueger-Gilbert Health Physics, Sentara Healthcare, Accuray Incorporated, CTSI, RTI Group North America, University of Louisville, Thomas Jefferson University Hospital, NCI, West Physics Consulting, LLC, Boston Children’s Hospital, CHOP, Greater Baltimore Medical Center, Florida Cancer Specialist & Research Institute, Radformation, Texas Oncology South Austin Cancer Center, Mosaic Life Care Cancer Center, University of Virginia, CPDS, Ravenel Oncology Center, M Health Fairview, Torrance Memorial Medical Center, RJK Medical Physics, Inc., NYU Langone-Long Island, Trinity CancerCare Center, Bryn Mawr Hospital, Sanford Health, University of Michigan Health Systems, One Physics - Ohio Medical Physics Consulting, West Michigan Cancer Center, University Hospitals Cleveland Medical Center, Levine Cancer Institute/Atrium Health, Advanced Biophotonics Laboratory, University of Massachusetts Lowell, UConn Health, U.S. Nuclear Regulatory Commission, Wayne State University, University of Oklahoma Health Science Center, Houston Methodist Hospital, Varian, Arizona Center for Cancer Care, NIH Clinical Center, Stanford University, Hospital of the University of Pennsylvania, Peel Regional Cancer Center, Credit Valley Hospital, University of Alabama Birmingham, Lark Physics, Ackerman Cancer Center, Southern District Health Board, Milestone Medical Physics Group, UTHealth Houston McGovern Medical School, Rutgers University, West County Radiological Group, Mayo Clinic, Philips Healthcare, University of Vermont Medical Center, Novant Health at Presbyterian Medical Center, Harvard Medical School, Ratio Therapeutics, Naval Medical Center Portsmouth, University Colorado Denver, School of Medicine, Sutter Santa Cruz Radiation Oncology, Radiophysics Associates, Northside Hospital, SolutionHealth, University of Virginia Health Systems, Johns Hopkins School of Medicine, Austin Health, UPMC, St. Joseph Mercy Health System, Cancer Center of Hawaii, Centra Health, Aspekt Solutions, Winter Haven Hospital, Henry Ford Hospital System, Medical University of South Carolina, Maine Medical Center, Phoenixville Hospital, National Institutes of Health, Associated Medical Professionals, Gundersen Health System, St. Luke's University Health Network, Univesity of Victoria, Department of Radiation Oncology, Stanford University School of Medicine, Washington University in St. Louis, Queen's Medical Center, West O'ahu, Canon Medical Research USA, Inc., Robert Wood Johnson University Hospital, UVA Health System, Section for Biomedical Physics, Department of Radiation Oncology, University Hospital and Medical Faculty, Eberhard Karls University Tübingen, Centennial Medical Physics, McLaren Cancer Institute, Cancer Care Group, Texas Oncology-Tyler, CTSI Oncology Practice Solutions, a varian company, Bank of Cyprus Oncology Centre, Columbus Regional Hospital, Central Florida Cancer Insititute, Texas Oncology - San Antonio, The Ohio State University, Stony Brook University, Greenwich Hospital, INOVA Schar Cancer Institute, Marsden Medical Physics Associates, Allegheny Health Network, Geisinger Health System, University of Maryland Medical System, Texas Oncology, Mount Sinai Medical Center, TrueNorth Medical Physics, Mallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, Houston Methodist Hospital, Houston, TX, Martin Memorial Medical Center, Yale University School of Medicine, Comprehensive Cancer Centers of Nevada, ASR Institute for Cancer Care, Research & Rehabilitation, University of Louisville Brown Cancer Center, Jaeger Corporation, UC San Francisco, Inova Hospital at Fairfax, Upstate Medical Physics, Cedars-Sinai Medical Center, Brown University Health, Texas Oncology-Denton, Assarian Cancer Center, HCA Healthcare, San Diego State University, Cooper University HealthCare, LVeldkamp MedPhys Services, LLC, Morristown Medical Center, Atlantic Health System, OMPC Therapy, LLC & OMPC Diagnostic, LLC, Defense Health Agency, Radiation Oncology, Medical College of Wisconsin, UT Southwestern Medical Center, Kaiser Permanente Bellflower Medical Center, Roswell Park Comprehensive Cancer Center, University of Victoria, MD Anderson Cancer Center at Cooper, Siemens Healthineers, Monmouth Medical Center, Memorial Sloan Kettering Cancer Center, Ironwood Cancer & Research Centers, University of Cincinnati, School of Medical Sciences, Fujita Health University, University of Kentucky/UK HealthCare, University of California, San Francisco, Instituto Nacional do Cancer, Brazil, IBA Dosimetry GmbH, Westchester Medical Center, Ohio State Univ, Houston Methodist, Medical College of Wisconsin, Columbia University Medical Center, Department of Radiation Oncology, College of Medicine, University of Arkansas for Medical Sciences, UT MD Anderson Cancer Center, DFCI/BWCC south shore, Providence Cancer Center, Memorial Sloan-Kettering Cancer Center, American Association of Physicists in Medicine, Lynn Cancer Institute - Radiation Oncology, Renown Health, Purdue Univ, Beth Israel Deaconess Medical Center, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Holy Family Hospital, OhioHealth, IBA Dosimetry, Memorial Hospital Gulfport, University of Florida, George Washington Univ, University of Cincinnati Medical Center, Hubbard, Zickgraf, & Broadbent, Accuray Inc, UVRMC, MIM Software, Massachusetts General Hospital and Harvard Medical School, Mem. Sloan Kettering Cancer Ctr, UF Health Proton Therapy Institute, California Medical Physics, Inc., Henry Ford Health, UPMC Hillman Cancer Center, Vanderbilt University School of Medicine, Saddleback Memorial Medical Center, Stony Brook University Medical Center, University of Pennslyvania, TOP Physics Consulting, Nuvance/Norwalk Hospital, Oregon Health & Science Univ, Brigham & Women's Hospital, University of Pennsylvania, McLaren – Greater Lansing, American Board of Radiology, Penn Medicine | Virtua Radiation Oncology, University of Tennessee, OneOncology, University of Colorado, Indiana University Medical Center, Stronach Regional Cancer Centre, Yale New Haven Health, Vanderbilt University Medical Center, Emory Healthcare / Winship Cancer Institute, Cape Fear Valley Radiation Oncology, Northwell Health, Sutter Health, Virginia Mason Medical Center, MUSC Health- Florence Medical Center, Departement of Radiation Oncology, Curie Institute, Paris, University of Michigan, MD Anderson Cancer Center, University of Alabama at Birmingham, Radiology Inc., Cedars Sinai Hospital, Roswell Park Cancer Institute, Duke University Health System, VA Hospital, DVA Medical Ctr., JFK Medical Center, Mount Sinai West, National Cancer Institute, Chung Nam National University Sejong Hospital, Indiana Univesity, AdventHealth Daytona Beach, Orlando Health, Clinical Research Institute HUS, Northwest Medical Physics Center, University of Pennsylvania, Penn Medicine, Kettering Health Network, Children's Mercy Kansas City, IBA, UMass Memorial Hospital, US Oncology, Kaiser Permanente Southern California Medical Group, The Queen's Health System, NewYork-Presbyterian, Miami Valley Hospital, Karlsruhe Institute of Technology, Piedmont Hospital, Accuray Inc., VARIAN - Advanced Oncology Solutions, GE Healthcare, Virtua Health, Northwestern Medicine Chicago Proton Center, CARO/Montgomery Cancer Center, Walter Reed National Military Medical Center, InterMountain Health Care, Englewood Hospital and Medical Center, Henry Ford Health System, Fluke Health Solutions, Texas Oncology, PA, Inova Alexandria Hospital, New Milford Hospital, Fox Chase Cancer Center, Radiation Therapy and Cancer Inst, Penn State College of Medicine, University of California San Francisco, Unity of Oncologic Therapy S.A., Canon Medical Systems USA, Kaiser Permanente, Baptist Health Paducah, Salina Regional Health, Centre d'Oncologie de la Cote Basque, Minneapolis Radiation Oncology, Coastal Carolina Radiation Oncology, Saint Francis Hospital, Advocate Christ Medical Ctr, Universidad de Costa Rica, CAMP, Blessing Hospital, Texas Oncology Cancer Ctr, CommonSpirit Health, Navy Medical Forces Atlantic, Regions Hospital, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Methodist Hospital, Champlain Valley Physicians Hospital, Mayo Clinic Jacksonville, OHSU, Promedica Health System, Arthur JE Child Comprehensive Cancer Centre, Rhode Island Hospital / Warren Alpert Medical, UPMC Pinnacle Health, Vassar Brothers Hospital, McLeod Regional Medical Center, RJ Tokarz MIRS, St. Francis Hospital, Astarita Associates, Inc., UC Davis Medical Center, Mount Nittany Medical Center, Covenant Radiation Center, National Institute of Standards and Technology, AdventHealth Orlando, St Helena Hospital, Icon Cancer Centre, University of Washington, Indiana University, TrueNorth Medical Physics LLC, Medstar Georgetown University Hospital, Harold Alfond Center for Cancer Care, MN Oncology, Jupiter Medical Center, GE HealthCare, Rochester General Hospital, Piedmont Health, Atrium Health, Minneapolis VA Health Care System, CentraCare Health System, OMPC Diagnostic LLC, Evergreen Health Medical Center, CAMC Cancer Center - Beckley, University of Kansas Medical Center, Avera McKennan, Cleveland Clinic, Louisiana Tech University

Abstract Preview: N/A...

Novel Methods to Select Patients for Functional Avoidance Radiotherapy

Authors: Vikas Aragam, Edward Castillo, Richard Castillo, Yingxuan Chen, Yevgeniy Vinogradskiy, Lydia J. Wilson

Affiliation: Thomas Jefferson University, Emory University, University of Texas at Austin

Abstract Preview: Purpose: 4DCT-based ventilation imaging (4DCT-ventilation) has been innovatively applied in radiotherapy treatment planning to minimize doses to functional portions of the lung, known as functional av...

Off- Axis Winston Lutz on C-Arm Linac Using in-House Phantom

Authors: Colton Baley, Bhuvaneswari Narayanan, Niko Papanikolaou, Daniel L. Saenz

Affiliation: UT Health San Antonio, Texas Oncology, University of Texas HSC San Antonio

Abstract Preview: Purpose: To evaluate the accuracy of off-axis winston lutz (WLT) for linac based stereotactic radiosurgery (SRS) treatments using in-house phantom.

Methods: Traditional WLT that uses cone and s...

Opentps: An Open-Source Radiotherapy Treatment Planning System to Foster Research, Innovation, and Education in Medical Physics

Authors: Ana Maria Barragan Montero, Damien Dasnoy, Sylvain Deffet, Valentine Dormal, Colin Gaban, Melanie Ghislaine, Valentin Hamaide, Guillaume Janssens, John A. Lee, Eliot Peeters, Danah Pross, Luciano Rivetti, Benjamin Roberfroid, Romain Schyns, Kevin Souris, Edmond S. Sterpin, Sophie Wuyckens

Affiliation: Ion Beam Applications SA, Hospital Riviera-Chablais, UCLouvain, Multitel, UniversitĂŠ Catholique de Louvain, IBA, Faculty of Mathematics and Physics, University of Ljubljana, Universite Catholique de Louvain

Abstract Preview: Purpose: Treatment planning systems (TPSs) are essential for simulating and optimizing radiotherapy treatments. However, clinical TPSs are expensive software commercialized by private companies and of...

Optimizing Fractionation Schedules for De-Escalation Radiotherapy in Head and Neck Cancers Using Deep Reinforcement Learning

Authors: Zhongjie Lu

Affiliation: Department of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine

Abstract Preview: Purpose: Patients with locally-advanced head and neck squamous cell carcinomas(HNSCCs), particularly those related to human papillomavirus(HPV), often achieve good locoregional control(LRC), yet they ...

Patient-Specific Bio-Morphological Features in Cherenkov Imaging for Positioning Verification: A Retrospective Analysis in Accelerated Partial Breast Irradiation (aPBI) VMAT Radiotherapy

Authors: Yao Chen, Lesley A Jarvis, Allison Matous, Rongxiao Zhang

Affiliation: Dartmouth College, University of Missouri, Dartmouth Cancer Center, Dartmouth Health

Abstract Preview: Purpose: Precise patient positioning is critical in accelerated partial breast irradiation (aPBI) to ensure accurate dose delivery to the tumor bed while minimizing exposure to surrounding healthy tis...

Planning and Delivering Homogenous Dose to Craniospinal Irradiation on Linear Accelerator

Authors: Issra Rashed, Jennie Wilder, Jingeng Zhu

Affiliation: Rush Riverside Cancer Institute, Advanced Oncology Solutions (AOS) Varian, a Siemens Healthineers company

Abstract Preview: Purpose: Develop a method to plan and deliver homogeneous dose to Craniospinal(CS) irradiation on Linear Accelerator.
Methods: Three treatment planning volumes (PTV) are created in sequence from su...

Precise Measurement of Leaf Open Time in Tomotherapy Using Advanced Plastic Scintillators

Authors: Marcos Feijoo, Mamoru Ichiki, Tatsuya Maeda, Tatsuhiro Makino, Tomonori Megumi, Tadashi Nakabayashi, Yukino Nakata, Shuichi Ozawa, Daishi Takayama

Affiliation: Hiroshima High-Precision Radiotherapy Cancer Center, Blue Physics LLC, Imamura General Hospital, Accuray Inc.

Abstract Preview: Purpose: This study aims to accurately measure the leaf open time (LOT) of the multi-leaf collimator (MLC) in tomotherapy using an advanced plastic scintillator detector (PSD) with high time resolutio...

Precision Radiotherapy Dose Prediction Using Foundation Model-Augmented Learning

Authors: Hilary P Bagshaw, Mark K Buyyounouski, Xianjin Dai, PhD, Praveenbalaji Rajendran, Lei Xing, Yong Yang

Affiliation: Department of Radiation Oncology, Stanford University, Massachusetts General Hospital, Harvard Medical School

Abstract Preview: Purpose: Artificial intelligence (AI)-driven methods have transformed dose prediction, streamlining the automation of radiotherapy treatment planning. However, traditional approaches depend exclusivel...

Predicting Hematologic Toxicity in Advanced Cervical Cancer Patients Using Interpretable Machine Learning Models Based on Radiomics and Dosimetrics

Authors: Qianxi Ni, Qionghui Zhou

Affiliation: The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University

Abstract Preview: Purpose:
This study aims to develop and evaluate interpretable machine learning models that use radiomic and dosimetric features to predict HT in advanced cervical cancer patients.
Methods:
R...

Proposed Method for Optimization of Lattice Radiation Therapy Using an Advanced Ring Gantry Linac

Authors: Eduardo Florian, Osmar Obdulio Hernandez, Otto Hurtarte, Milton Ixquiac, Erick Orlando Montenegro, Franky Eduardo Reyes, Edgar Aparicio Ruiz, Kevin Vega, Vicky de Falla

Affiliation: Liga Nacional Contra el Cancer, Liga Nacional Contra el Cancer/INCAN, Liga Nacional Contra el Cancer / INCAN, Liga Nacional Contra el Cancer and Universidad de San Carlos de Guatemala, Liga Nacional Contra el CĂĄncer / INCAN

Abstract Preview: Introduccion:
Lattice Radiation Therapy (LRT) is a form of spatially fractionated radiation therapy (SFRT) designed to improve control of large tumors by delivering ablative doses while minimizing ...

Quantifying Cervical Cancer Radiotherapy Care Gap in Uganda: Baseline Assessment Prior to Implementation of a Custom Mobile Health App.

Authors: Eric C. Ford, Awusi Kavuma, Solomon Kibudde, Lilie Lin, Apollo Muramuzi, Nibedita Paul, Peniel T Twum, Afua A. Yorke

Affiliation: Uganda Cancer Institute, MD Anderson Cancer Center, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Nebraska, Global Communities

Abstract Preview: Purpose: Sub-Saharan Africa accounts for over one-third of global cervical cancer deaths, despite representing only 14% of the world’s female population. At the only RT center in Uganda, prior studies...

Ratoguide: Evaluation of AI-Driven Fully Automated Treatment Planning Support System for Lung SBRT

Authors: Keiichi Jingu, Noriyuki Kadoya, Takafumi Komiyama, Takeru Nakajima, Hikaru Nemoto, Hiroshi Onishi, Masahide Saito, Ryota Tozuka

Affiliation: Department of Radiology, University of Yamanashi, Department of Radiation Oncology, Tohoku University Graduate School of Medicine, Department of Advanced Biomedical Imaging, University of Yamanashi

Abstract Preview: Purpose: We evaluated the accuracy of a new AI-based fully automated planning software in stereotactic body radiotherapy (SBRT) for early-stage lung cancer.
Methods: We collected data from 125 pati...

Real-Time Fully Automated IMRT Planning without Optimization Process Using a Two-Step AI Framework

Authors: Daisuke Kawahara, Takaaki Matsuura, Yuji Murakami, Ryunosuke Yanagida

Affiliation: Hiroshima High-Precision Radiotherapy Cancer Center, Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima

Abstract Preview: Purpose: In recent years, automation in radiation therapy planning using AI has gained significant attention to reduce the workload of treatment planners. Adaptive Radiation Therapy (ART), as a new fo...

Redefining the Down-Sampling Scheme of U-Net for Precision Biomedical Image Segmentation

Authors: Yizheng Chen, Md Tauhidul Islam, Mingjie Li, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose:
Biomedical image segmentation (BIS) is a cornerstone of medical physics, enabling accurate delineation of anatomical structures and abnormalities, which is critical for diagnosis, treatmen...

Retrospective Evaluation of Combined Photon SBRT and Radium-223 SPECT Based Radiopharmaceutical Therapy Tumor Dosimetry in Clinical Trial Patient Cases

Authors: David P. Adam, Allison Cartee, Eric C. Frey, Michael Ghaly, Bin He, Robert Francois Hobbs, Natalie Rose Kania, Ana Kiess, Ian Marsh, Bonnie N. C. President, Steven Rowe, George Sgouros, Phuoc Tran, Hao Wang

Affiliation: Johns Hopkins University, Radiopharmaceutical Imaging and Dosimetry, LLC (Rapid), 2The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins Medical Institute, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Oncology, Johns Hopkins University, School of Medicine, Department of Radiology, University of North Carolina, Chapel Hill

Abstract Preview: Purpose: Advanced treatment paradigms combining SPECT/CT imageable, alpha emitting, radiopharmaceutical therapy (RPT) and stereotactic body radiotherapy (SBRT) can provide the potential of dose escala...

Simulating Realistic Digital Phantoms for Virtual Clinical Trials in Radiology and Radiation Oncology Using a Deep-Learning Based Conditional Denoising Diffusion Probabilistic Model (c-DDPM)

Authors: Matthew Brown, Yushi Chang, Jinhyuk Choi, William Silva Mendes, Lei Ren, Aman Sangal, William Paul Segars, Phuoc Tran, Hualiang Zhong

Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Digital phantoms like XCAT are essential for imaging and treatment optimization in radiology and radiation oncology. However, the lack of realistic textures (HU distribution) in XCAT limits i...

Spatially Informed Auto-Segmentation of Cardiac Nodes for Radiotherapy Treatment Planning

Authors: Ming Dong, Carri K. Glide-Hurst, Joshua Pan, Nicholas R. Summerfield

Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Radiation dose to the cardiac nodes is more strongly associated with conduction disorders and arrythmias than whole heart (WH) metrics. However, node segmentation is challenging due to comple...

Stereotactic Body Radiosurgery for Refractory Ventricular Tachycardia: Presenting Efficient Clinic Workflow, Dosimetric Analysis and Patients Reported Clinical Results

Authors: Karam Ayoub, Aaron B Hesselson, Ronald C McGarry, Joshua Misa, Damodar Pokhrel

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Department of Cardiology

Abstract Preview: Purpose: Noninvasive stereotactic body radiosurgery (SBRS) is emerging treatment option for advanced heart failure patients with refractory-ventricular tachycardia (rVT) who experienced recurrent impl...

Tackling the Challenge of Multi-Target Metastases Treatment: Evaluation of Ethos Treatment Planning System

Authors: Avery Antes, Bulent Aydogan, Rama Chicfeh, Erik Pearson, Neslihan Sarigul

Affiliation: The University Of Chicago, The University of Chicago

Abstract Preview: Purpose: This study evaluates the performance of the Ethos Treatment Planning System (TPS) in managing oligometastatic cancer patients previously treated using multiple isocenter plans.
Methods: Th...

The GYN Webapp: A Centralized Tool for Enhancing HDR Brachytherapy Treatment Quality and Clinical Outcomes

Authors: Kevin Albuquerque, Ti Bai, Yesenia Gonzalez, Brian A. Hrycushko, Zohaib Iqbal, Paul M. Medin, Shanshan Tang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Cervical cancer remains one of the most common and significant gynecological (GYN) malignancies globally, often presenting at advanced stages where radiation therapy and high-dose-rate (HDR) ...

The Topas Monte Carlo Framework – Status and Outlook after 15 Years of Development

Authors: Alejandro Bertolet, Jorge Naoki Dominguez Kondo, Bruce A. Faddegon, Thongchai Masilela, Isaac Meyer, Victor V. Onecha, Harald Paganetti, Jose A. Ramos-Mendez, Jan PO Schuemann, Wook-Geun Shin

Affiliation: University of California San Francisco, Massachusetts General Hospital and Harvard Medical School, Massachusetts General Hospital

Abstract Preview: Purpose: To present the results of 15 years of developments of the TOPAS TOol for PArticle Simulation framework, and to highlight recent and new developments.

Methods: Fundamental understanding...

To Investigate the Utility of Magnetic Resonance Imaging (MRI)-Based Radiomics for Predicting Tumor Response and Adverse Effects, Specifically Gastrointestinal (GI) Toxicity, in Cervical Cancer Patients Undergone Radiotherapy.

Authors: Issam M. El Naqa, Kurukulasuriya Ruwani Fernando, Himani Himani, Vivek Kumar, Arun Oinam, Manju Sharma

Affiliation: Panjab University, Moffitt Cancer Center, H. Lee Moffitt Cancer Center, Post Graduate Institute of Medical Sciences, University of California San Francisco

Abstract Preview: Purpose: To investigate the utility of Magnetic Resonance Imaging (MRI)-based radiomics for predicting tumor response and adverse effects, specifically gastrointestinal (GI) toxicity, in cervical canc...

Towards AI Decision-Support for Online Adaptive Radiotherapy (oART): A Preliminary Study on CBCT-Guided Post-Prostatectomy Oart

Authors: Michael Cummings, Olga M. Dona Lemus, Hana Mekdash, Tyler Moran, Alexander R Podgorsak, Sean M. Tanny, Matthew J. Webster, Lexiang Yang, Dandan Zheng, Yuwei Zhou, Xiaofeng Zhu

Affiliation: Department of Radiation Oncology, University of Rochester, University of Miami, Inova Schar Cancer Institute, University of Rochester

Abstract Preview: Purpose: oART is revolutionizing radiotherapy by allowing treatment plans to be adjusted based on daily imaging, improving targeting precision and potentially enhancing patient outcomes. However, its ...

Treatment Plan Evaluation of the Patient-Tailored Architect Applicator for Cervical Cancer Brachytherapy

Authors: Jenny Dankelman, Ben J. M. Heijmen, Inger-Karine K. Kolkman-Deurloo, Remi A. Nout, Linda Rossi, Robin Straathof, Linda Wauben, Henrike Westerveld, Nick J. van De Berg, Sharline M. van Vliet - Perez

Affiliation: Department of BioMechanical Engineering, Delft University of Technology, Department of Gynecological Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam

Abstract Preview: Purpose:
To quantify the dosimetric advantages of the 3D-printed patient-tailored ARCHITECT applicator with optimized needle channel configurations compared to clinically used intracavitary/interst...

Two-Stage Clustering and Auto Machine Learning to Predict Chemoradiation Response in Tumor Subregions on FDG PET for La-NSCLC

Authors: Stephen R. Bowen, Shijun Chen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Qianqian Tong, Jiajie Wang, Shouyi Wang, Faisal Yaseen

Affiliation: The University of Texas at Austin, Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Fred Hutchinson Cancer Center, University of Texas at Arlington

Abstract Preview: Purpose: Tumor subregion clustering and prediction of region-specific response can augment assessments and adaptive treatment decisions. A modeling framework was constructed to predict chemoradiation ...

Ultra-Fast Commissioning and Quality Assurance with Plastic Scintillation Detector

Authors: Saad Bin Saeed Ahmed, Marcos Feijoo, Wazir Muhammad, Charles Shang, Naseem Ud Din

Affiliation: South Florida Proton Therapy Institute, Miami Cancer Institute, Blue Physics LLC, Florida Atlantic University

Abstract Preview: Purpose: Accurate, efficient, and reliable commissioning of linear accelerator (LINAC) is critical for ensuring high-quality radiation therapy treatments. The study uses advanced detector technology a...

Unlocking Adaptive Radiotherapy Flexibility: Integrating Ethos Adaptive Therapy and Halcyon IGRT with Scripting Innovations

Authors: Min Geon Choi, Sean J. Domal, Ruiqi Li, Taoran Li, Mu-Han Lin, Yang Kyun Park, David D.M. Parsons, Justin D. Visak

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, University of Pennsylvania, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Ethos X-ray-guided online adaptive radiotherapy (ART) enables precise, daily adaptive treatments but requires significant resources, limiting widespread adoption. Many treatment sites do not ...

Volumetric-Modulated Arc Therapy (VMAT) Is Associated with Improved Dose Homogeneity, but More Normal Tissue Irradiation Compared to Three-Dimensional Conformal Radiation Therapy (3DCRT) for Breast Cancer

Authors: Laura I. Cervino, Linda X. Hong, Jessica Pagan, Angelica A. Perez-Andujar, Maria Thor

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Memorial Sloan-Kettering Cancer Center

Abstract Preview: Purpose: Three-dimensional conformal radiotherapy (3DCRT) and Volumetric-Modulated Arc Therapy (VMAT) are used to treat locally advanced breast cancer. The 3DCRT treatment plans use the treatment fiel...