Authors: Huay Din, Grace Jianan Gang, Grace Hyun Kim, Michael F. McNitt-Gray, Joseph W. Stayman, Yijie Yuan
Affiliation: Johns Hopkins University, John Hopkins University, University of Pennsylvania, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose:
Radiomics rely on quantitative features to discern underlying biological signatures. However, feature dependence on the imaging systems themselves hampers the creation of reproducible and ...
Authors: Julien Bancheri, Jan P. Seuntjens
Affiliation: Medical Biophysics, University of Toronto, Princess Margaret Cancer Centre & University of Toronto
Abstract Preview: Purpose: To obtain an analytical expression for the charge collection efficiency of parallel-plate ionization chambers in high dose-per-pulse (DPP) beams that takes into account the square pulse time ...
Authors: David Brizel, Kyle J. Lafata, Jian-Guo Liu, Yvonne M Mowery, Yvonne M Mowery, William Paul Segars, Jack B Stevens
Affiliation: Department of Physics, Duke University, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh
Abstract Preview: Purpose: To develop a technique to quantify tumor topology using a unifying mathematical framework that integrates texture and morphology and to evaluate its feasibility as a prognostic biomarker for ...
Authors: Cheewai Cheng, Indra J. Das, Jeffrey Yui Hei Wong, Poonam Yadav
Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine
Abstract Preview: Purpose: Radiation treatment machine replacement brings chaos and urgency of timely completion of machine commissioning for every procedure used including TBI that are time consuming. Based on past ex...
Authors: Wenbo Gu, Chenhui Qiu, Ke Sheng, Liyan Sun, Weiyuan Sun, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiology, Stanford University, University of Pennsylvania, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, Stanford University,
Abstract Preview: Purpose:
The small animal radio-neuromodulation platform developed in our previous work utilized focused kV x-ray beams rotating and translating in predefined trajectories to irradiate small, mm si...
Authors: Santosh K. Agarwalla, Nrusingh C. Biswal, Shree C, Harikrishnan Suresh Kumar, Jajati K. Nayak, Prema P., Sarath K S, Tamil Selvan S, Hem D. Shukla
Affiliation: Variable Energy Cyclotron Centre, Department of Physics, Fakir Mohan University, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Sciences, Amrita Vishwa Vidyapeetham
Abstract Preview: Purpose: The rapid oxygen depletion in tissues during irradiation is the most accepted mechanism of the FLASH effect. However, the Normal Tissue Complication Probability (NTCP) and Tumor Control Proba...
Authors: Petr Bruza, Megan Clark, David J. Gladstone, Joseph Harms, Anthony E. Mascia, Brian W Pogue, Roman Vasyltsiv, Zhiyan Xiao, Rongxiao Zhang, Yongbin Zhang
Affiliation: Cincinnati Children's Proton Therapy Center, University of Missouri, Dartmouth College, Thayer School of Engineering, Dartmouth College, Washington University in St. Louis, University of Wisconsin - Madison
Abstract Preview: Purpose: With developing FLASH trials requiring diligent delivery monitoring, current proton therapy in-vivo dosimetry (IVD) cannot provide comprehensive verification, including dose and dose-rate vol...
Authors: Julia Bauer, Tianxue Du, Katia Parodi, Marco Pinto, Thomas Tessonnier
Affiliation: Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Heidelberg Ion Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich)
Abstract Preview: Purpose:
Carbon ion therapy could benefit from range verification due to its sensitivity to range uncertainties. Positron emission tomography (PET) aids in this and comparing irradiation-induced PE...
Authors: Sabrina Campelo, Sandun Y. Jayarathna, Adam D. Melancon, Paige L. Nitsch, Christopher Ryan Peeler, Julianne M. Pollard-Larkin, Ramaswamy Sadagopan, Xiaochun Wang, George Zhao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Development of an in-house analytical simulation for streamlining photon counting detector (PCD) system protocols through measuring transmitted photon energy spectra through a Hafnium (Hf)-lo...
Authors: Tae Kyu Lee
Affiliation: Allina Health
Abstract Preview: Purpose: To assess the feasibility of a dynamic-platform integrated with high-resolution patient-specific-quality-assurance (PSQ device for periodic quality assurance (PQA) and PSQA in respiratory-gat...
Authors: Prabhu C. Acharya, Hassan Bagher-Ebadian, Stephen L. Brown, James R. Ewing, Mohammad M. Ghassemi, Benjamin Movsas, Farzan Siddiqui, Kundan S Thind
Affiliation: Michigan State University, Oakland University, Henry Ford Health
Abstract Preview: Purpose: Accurate T1 quantification using T One by Multiple Read Out Pulse (TOMROP) sequences is essential for physiological assessments in dynamic-contrast-enhanced (DCE) MRI and T1 mapping studies. ...
Authors: Dirk A Bartkoski, Michael Kleckner, Dongyeon Lee, Reza Reiazi, Mohammad Reza Salehpour
Affiliation: The University of Texas MD Anderson Cancer Center, Convergent-RnR
Abstract Preview: Purpose:
To develop and validate G4BraggReflection, a novel physics process within Geant4, designed to incorporate diffraction properties resulting in Bragg reflection into Monte Carlo simulations....
Authors: Yu Gao, Lei Xing, Siqi Ye
Affiliation: Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) scans are often the only option for non-coplanar radiation therapy to prevent potential mechanical collisions. However, the consecutive angular occlusion of pr...
Authors: Giavanna Luisa Jadick, Patrick J La Riviere, Cailey Riggs
Affiliation: University of Chicago
Abstract Preview: Purpose: We explore the accuracy of physics models for propagation-based x-ray phase-contrast imaging (XPCI) with an eye to future clinical implementation, providing a practical assessment of detectio...
Authors: Zijia Guo, Viktor Haase, Michael F. McNitt-Gray, Frederic Noo
Affiliation: Siemens Healthineers, University of Utah, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose: The attenuation values in CT hold strong potential for disease diagnosis. However, they lack reliability, which has limited their use to clinical trials where variability can be controlled. S...