Authors: Arash Bedayat, Jason Bradfield, Minsong Cao, Robert K Chin, Huiming Dong, J Paul Finn, Fei Han, Justin Hayase, Shu-Fu Shih, Xiaodong Zhong
Affiliation: Cardiac Electrophysiology, University of California, Los Angeles, Department of Radiation Oncology, University of California, Los Angeles, Department of Radiology, University of California, Los Angeles, Siemens Healthineers
Abstract Preview: Purpose: Cardiac SBRT is a promising treatment for ventricular tachycardia (VT). Success depends on accurate target delineation, for which 2D narrowband late gadolinium-enhanced (LGE) MRI offers valua...
Authors: Hongyu An, Phillip Cuculich, H Michael Gach, Yao Hao, Trevor McKeown, Clifford Robinson, Yuhao Wang, Deshan Yang
Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, Duke University, Department of Radiation Oncology, Duke University, Washington University in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis
Abstract Preview: Purpose: Cardiorespiratory motion management is crucial in stereotactic arrhythmia radiotherapy to define target margins and minimize cardiac toxicity. While respiratory 4DCT (r4DCT) images can infer ...
Authors: Anna E. Rodrigues, Yuhao Wang, Deshan Yang
Affiliation: Duke University, Department of Radiation Oncology, Duke University
Abstract Preview: Purpose: Accurate motion margin definition in StereoTactic Arrhythmia Radiotherapy (STAR) requires accurate cardiorespiratory motion assessment. However, respiratory 4DCT (r4DCT) images are affected b...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Dual-energy imaging offers benefits, including metal artifact reductions (MAR) and improved contrast, that enhance visualization. Currently, dual-energy imaging is largely limited to CT scann...
Authors: Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Joseph Shields, Christopher Tyerech
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pennsylvania, UPMC
Abstract Preview: Purpose: HyperSight is a new platform for image-guided radiation therapy, offering advanced reconstruction algorithms, a large field-of-view, and rapid acquisition times. To validate the performance o...
Authors: Rani Anne', Wenchao Cao, Yingxuan Chen, Wookjin Choi, Firas Mourtada, Yevgeniy Vinogradskiy
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: In-room mobile cone-beam CT (CBCT) is emerging to enhance high-dose-rate (HDR) brachytherapy workflow using on-demand imaging. However, metal artifacts from X-ray markers inside gynecological...
Authors: Zhiqiang Chen, Hewei Gao, Li Zhang, Guoxi Zhu
Affiliation: Tsinghua University
Abstract Preview: Purpose: Spectral cone-beam CT has better performance in material identification and quantitative analysis compared to single-energy cone-beam CT. However, X-ray scattering introduces significant scat...
Authors: John T Barrett, Mehnaz Haque, Chulhaeng Huh, Shands James, Thomas B. Lavin, Anobel Maghsoodpour, Farshad Mostafaei, Austin Sanders
Affiliation: Department of Radiation Oncology, Augusta University, Department of Radiation Oncology, Medical College of Georgia, Augusta University, Georgia Radiation Therapy Center, Wellstar-MCG Health, Department of Radiation Oncology, Doctors Hospital of Augusta, Department of Radiology and Imaging, Augusta University
Abstract Preview: Purpose: This study assesses Philips’ O-MAR effectiveness in adjusting AVHU values of common anatomical materials affected by various high-density metal artifacts at varying distances.
Methods:...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski, Huanyi Zhou
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose: A new CT configuration utilizing a multiple X-ray-source array (MXA) is under development to mitigate cone-beam (CB) artifacts in single-rotation wide coverage imaging. We investigate the sam...
Authors: Girish Bal, Thomas I. Banks, Bin Cai, Yesenia Gonzalez, Zohaib Iqbal, Paul M. Medin, Rameshwar Prasad, Chenyang Shen, Robert Timmerman, Yuanyuan Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: Each year more than one million pacemakers and 200k cardioverter-defibrillators are implanted in patients worldwide. The presence of a CIED introduces challenges to the delivery of radiation ...
Authors: Alan Rui Li, Qihui Lyu, Dan Ruan, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
The Sparse Primary Sampling (SPS) grid was shown in a previous computational study to improve image quality by correcting scatter-induced effects and artifacts in Cone-beam Computed Tomogr...
Authors: Sarah Aubert, Harald Keller, Jeff D. Winter
Affiliation: Princess Margaret Cancer Centre
Abstract Preview: Purpose: Support for treatment planning directly on CBCT imaging on C-arm linacs will enable adaptive radiation therapy (ART) capacity with increased treatment technique flexibility. The HyperSight im...
Authors: Laura I. Cervino, Karen Episcopia, Hsiang-Chi Kuo, Sangkyu Lee, Seng Boh Gary Lim, Shih-Chi Lin, Grace Tang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: This study evaluated the performance of the HyperSight Cone-Beam Computed Tomography (CBCT) system on a TrueBeam C-arm LINAC (TB) and two Ethos ring-gantry LINACs (ES) for adaptive radiation ...
Authors: Magdalena Bazalova-Carter, James Day, Xinchen Deng
Affiliation: University of Victoria
Abstract Preview: Purpose:
Ring artifacts in Photon-Counting Computed Tomography (PCCT) images can degrade image quality. this study aims to suppress ring artifacts with a novel autoencoder-based framework that leve...
Authors: Alexander Bookbinder, Matthew Tivnan, Xiangyi Wu, Wei Zhao
Affiliation: Stony Brook Medicine, Massachusetts General Hospital
Abstract Preview: Purpose: To investigate and benchmark a system-adaptive diffusion-based digital breast tomosynthesis (DBT) denoising model for a direct-indirect dual-layer flat panel detector (DI-DLFPD) with a k-edge...
Authors: John M. Boone, Andrew M. Hernandez, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski
Affiliation: Johns Hopkins University, University of California, UT MD Anderson Cancer Center, University of New Mexico Albuquerque, UC Davis Health
Abstract Preview: Purpose: To significantly improve image quality relative to clinically deployed digital breast tomosynthesis (DBT) systems, which use a 1D acquisition geometry (an arc), with a 2D image acquisition ge...
Authors: Michael J. Choi, Vindu Wathsala Kathriarachchi, Christopher L. Nelson, Andrew P. Soderstrom, Yawei Zhang
Affiliation: The University of Texas MD Anderson Cancer Center, MD Anderson, UF Health Proton Therapy Institute
Abstract Preview: Purpose: Cone Beam Computed Tomography (CBCT) is widely used in image-guided radiation therapy for patient positioning. While kV photons offer high image contrast, they are prone to artifacts caused b...
Authors: Xiaoyi Dai, Manju Liu, Weiwei Sang, Pulin Sun, Fan Xia, Zhenyu Yang, Fang-Fang Yin, Chulong Zhang, Rihui Zhang
Affiliation: Jiahui International Hospital, Radiation Oncology, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose:
Current deep learning-based sparse-view CBCT reconstruction methods are prone to hallucinatory artifacts, as they rely on inferred image details that may not correspond to true anatomical ...
Authors: Edward Robert Criscuolo, Chenlu Qin, Deshan Yang, Zhendong Zhang
Affiliation: Duke University, Department of Radiation Oncology, Duke University
Abstract Preview: Purpose:
Low-dose CT (LDCT) imaging minimizes radiation exposure but introduces significant noise, compromising image quality. While deep learning-based denoising models such as HFormer achieve sta...
Authors: Yi-Fang Wang, Yading Yuan
Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology, Columbia University Irving Medical Center
Abstract Preview: Purpose: HyperSight, the latest CBCT technology from Varian Medical Systems, integrates rapid 6-second data acquisition with advanced iterative reconstruction and upgraded hardware. Previous studies h...
Authors: Laura Bennett, Matthew Charles, Greg Cooley, John M. Floberg, Ryan Hutten, Elissa Khoudary, Nicholas Lynch, Kaili Ranta, Jordan M. Slagowski, Trevor Wilson
Affiliation: University of Pennsylvania, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, University of Wisconsin-Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: To evaluate the impact of an iterative cone beam CT with metal artifact reduction (iCBCT+MAR) reconstruction algorithm (HyperSight TrueBeam 4.1, Varian Medical Systems) on image quality and s...
Authors: Jochen Cammin, Shifeng Chen, Arun Gopal, Kai Huang, Jason K Molitoris, Amit Sawant, Kai Wang
Affiliation: University of Maryland, Department of Radiation Oncology, University of Maryland School of Medicine, Maryland University Baltimore, Department of Radiation Oncology, University of Maryland Medical Center
Abstract Preview: Purpose: The HyperSight CBCT optional feature on Varian TrueBeam linacs offers a larger field-of-view, improved Hounsfield units (HU) accuracy, and overall improved image quality, including metal arti...
Authors: Renee Farrell, Jinkoo Kim, Xin Qian, Ziyu Shu, Zhaozheng Yin, Tiezhi Zhang
Affiliation: Stony Brook Medicine, Washington University in St. Louis, Stony Brook University, Stony Brook University Hospital
Abstract Preview: Purpose: Ultra-short CT scan allows fast imaging speed, dose reduction, and compact system design. We developed a deep image prior (DIP) based reconstruction method named Hybrid Prior-Enhanced Deep Im...
Authors: Salman M. Arnab, Yves Chevalier, Samuel Gagné, Adrian F. Howansky, Luc Laperrière, Xiangyi Wu, Wei Zhao
Affiliation: Stony Brook Medicine, Analogic Canada
Abstract Preview: Purpose: A direct-indirect dual-layer flat-panel-detector (DI-DLFPD) is under development for patient motion artifact-free contrast-enhanced digital mammography (CEDM). DI-DLFPD comprises a direct fro...
Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Christian Erik Petersen, Alex T. Price, Atefeh Rezaei, Runyon C. Woods
Affiliation: University Hospitals Seidman Cancer Center
Abstract Preview: Purpose: CBCT is subject to more artifacts due to increased photon scatter, especially in areas of increased tissue heterogeneities compared to fan-beam CTs (FBCTs). Improved imaging panels combined w...
Authors: Wendy Siman, Wei Zhou
Affiliation: University of Colorado Anschutz Medical Campus, School of Medicine
Abstract Preview: Purpose:
To compare the image quality and radiation dose of 3D cone-beam CT modes of a mobile C-arm and an O-arm unit for intraoperative imaging.
Methods:
A 50-µm tungsten wire was imaged at ...
Authors: Harald Keller, Iymad Mansour, Jeff D. Winter
Affiliation: Princess Margaret Cancer Centre
Abstract Preview: Purpose: The growing number of adaptive therapy applications is motivating image segmentation and direct dose calculation on CBCT. The purpose of this investigation is to evaluate the recently release...
Authors: Shusen Jing, Qihui Lyu, Dan Ruan, Ke Sheng, Qifan Xu
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: Metallic implants can significantly distort sinograms, leading to severe artifacts in computed tomography (CT) reconstructions. Reconstructing CT images containing metal is fundamentally an i...
Authors: Gregory J Bootsma, Tunok Mondol
Affiliation: University Health Network, Princess Margaret Cancer Center
Abstract Preview: Purpose:
To evaluate the impact of prototype fluence field modulation (FFM) cone-beam CT (CBCT) on dose reduction and image quality using Monte Carlo simulations. This study particularly looks at t...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Sarah E. McKenney, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose:
While wide coverage (160 mm) CT scanners can image whole organs (e.g. heart, brain, kidneys, etc.) in one axial scan, the peripheral regions of the field of view (along z) suffer from cons...
Authors: Jia Wang, Vani Yadav
Affiliation: Stanford University
Abstract Preview: Purpose: To evaluate the radiation dose and imaging quality of two novel CBCT X-Ray imaging systems used in spine surgeries.
Methods: CBCT scan of ACR CT and CTDI phantoms was performed to acquire ...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Nicholas Lowther, Daniel Morf, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Womens Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Multi-layer flat-panel imagers can improve for clinical image-guided radiotherapy applications, including the enhanced visualization of soft tissue and a reduction in image artifacts. Each im...
Authors: Karyn A Goodman, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Qian Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Beth Israel Deaconess Medical Center
Abstract Preview: Purpose: Accurate motion management in MRI-guided radiotherapy (MRIgRT) relies on real-time volumetric MRI to track intra-fractional anatomical changes. Dense k-space sampling, while capable of produc...
Authors: Loren Bell, Charles S Cathcart, Brett William Eckroate, Harold Y Hu, Joshua Kilian-Meneghin, Ke Nie, Fredrick Warburton, Zhenyu Xiong, Keying (Karen) Xu, Ning J. Yue, Yin Zhang, Lili Zhou
Affiliation: RWJBarnabas Health, Basis Scottsdale, Rutgers Cancer Institute of New Jersey
Abstract Preview: Purpose: This study compares the dosimetric impact of multiple metal artifact reduction (MAR) algorithms from different CT simulator vendors using an anthropomorphic head phantom for head-and-neck (H/...
Authors: Geoffrey D. Hugo, Eric Laugeman, Thomas R. Mazur, Pamela Samson, Kim A. Selting, Zhehao Zhang
Affiliation: University of Illinois, Washington University in St. Louis School of Medicine, WashU Medicine
Abstract Preview: Purpose: To investigate the robustness of a deep learning (DL)-based 4D-CBCT motion-compensated (MoCo) reconstruction method to out-of-distribution data.
Methods: Our developed 4D-CBCT reconstructi...
Authors: Hua-Chieh Shao, Shanshan Tang, Jing Wang, Kai Wang, You Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, University of Maryland Medical Center
Abstract Preview: Purpose: Artifacts caused by gas bubble movement in the gastrointestinal tract can severely degrade the image quality of on-board abdominal cone-beam computed tomography (CBCT), impacting its utility ...
Authors: Xinhui Duan, Vivek Nair, Liqiang Ren, KyuHo Song, Kuan Zhang, Yue Zhang
Affiliation: Department of Radiology, UT Southwestern Medical Center
Abstract Preview: Purpose: To evaluate how tin-filtered spectral shaping in clinical photon-counting computed tomography (PCCT) affects noise magnitude across varying object sizes, radiation doses, and spectral reconst...
Authors: Owen Thomas Dillon, Andrew Kanawati, Tess Reynolds
Affiliation: Westmead Hospital, Image X Institute, Faculty of Medicine and Health, The University of Sydney
Abstract Preview: Purpose: Metal artefacts from implanted hardware and surgical tools remain a limitation for widespread adoption of intraoperative CBCT imaging. Gantry-based non-circular imaging trajectories have emer...
Authors: Les Butler, Joyoni Dey, Conner B Dooley, Victoria L Fontenot, Kyungmin Ham, Hunter Cole Meyer
Affiliation: Louisiana State University, Center for Advanced Microstructures and Devices, Linfield University
Abstract Preview: Purpose: X-ray interferometry is an emerging imaging modality with a wide variety of potential clinical applications, including lung and breast imaging. Small inaccuracies in grating position lead to ...