Authors: Aditya P. Apte, Xinan Chen, Joseph O. Deasy, Ramesh Paudyal, Kyung Peck, Amita Shukla-Dave, Nathaniel Swinburne, Robert J. Young
Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: We apply our novel formulation of unbalanced-regularized-optimal-mass-transport (urOMT) theory to brain DCE-MRI data to quantify and visualize the behaviors of fluid flows in post-treatment f...
Authors: Maria Jose Almada, Bruno Forti, Andres Lima, Carlos Daniel Venencia
Affiliation: Instituto Zunino - Fundacion Marie Curie
Abstract Preview: Purpose:
To automate the planning of radiotherapy treatments for bone metastases using a script in the ECLIPSE planning system version 15.6 with a graphical interface.
Methods:
A script was d...
Authors: Evan Calabrese, Hangjie Ji, Kyle J. Lafata, Casey Y. Lee, Eugene Vaios, Chunhao Wang, Lana Wang, Zhenyu Yang, Jingtong Zhao
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Duke Kunshan University, North Carolina State University
Abstract Preview: Purpose: To develop a biologically guided deep learning (DL) model for predicting brain metastasis(BM) local control outcomes following stereotactic radiosurgery (SRS). By integrating pre-SRS MR image...
Authors: Rex Carden, Carlos E. Cardenas, Ho-hsin Rita Chang, John B Fiveash, Heinzman A. Katherine, Yogesh Kumar, Gaurav Nitin Rathi, Richard A. Popple, Kayla Lewis Steed
Affiliation: University of Alabama at Birmingham
Abstract Preview: Purpose: Brain metastases (BMs) often require multiple radiotherapy (RT) courses as new lesions appear. Comparing follow-up imaging with prior RT plans is time-intensive. We developed an AI tool that ...
Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital
Abstract Preview: Purpose: Our GammaKnife(GK) has been upgraded from 4C to ICON recently. In this study we evaluated the performance of Lightning IPO for ICON.
Methods: 10 cases with single brain metastasis previous...
Authors: Michael Dohopolski, Jiaqi Liu, Hao Peng, Robert Timmerman, Zabi Wardak, Haozhao Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
This study introduces a gradient-based radiomics framework to enhance outcome prediction in Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR) for brain metastases...
Authors: Omar Awad, Alfredo Enrique Echeverria, Issam M. El Naqa, Daniel Allan Hamstra, Yiding Han, Ryan Lafratta, Abdallah Sherif Radwan Mohamed, Piyush Pathak, Zaid Ali Siddiqui, Baozhou Sun, Vincent Ugarte
Affiliation: H. Lee Moffitt Cancer Center, Harris Health, Baylor College of Medicine
Abstract Preview: Purpose:
Accurate detection and segmentation of brain metastases are critical for diagnosis, treatment planning, and follow-up imaging but are challenging due to labor-intensive manual assessments ...
Authors: Eyub Y. Akdemir, Gregory A Azzam, Rupesh Kotecha, Gregory J. Kubicek, Natalia Lutsik, Eric Mellon, Siamak P. Nejad-Davarani, Parag Parikh, Karen C. Snyder
Affiliation: Miami Cancer Institute, Baptist Health South Florida, Department of Radiation Oncology, University of Miami, Henry Ford Health
Abstract Preview: Purpose: Resection cavity volumes shrink gradually over time after surgical resection of brain metastases. Fractionated stereotactic radiosurgery (fSRS) is often delivered to the cavity to prevent rec...
Authors: Yufeng Cao, Luigi Marchionni, William Silva Mendes, Cem Onal, Lei Ren, Amit Sawant, Nicole L Simone, Philip Sutera, Phuoc Tran
Affiliation: University of Maryland School of Medicine, 9Department of Radiation Oncology, Thomas Jefferson University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, University of Maryland, Baltimore, Baskent University Faculty of Medicine, Department of Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine, Maryland University Baltimore, 8Department of Pathology and Laboratory Medicine, Weill Cornell Medicine
Abstract Preview: Purpose: This study aims to predict 2-yr Metastasis-free survival (MFS) for oligometastatic castration-sensitive prostate cancer (omCSPC) patients treated by metastasis-directed therapy (MDT) by devel...
Authors: J. Daniel Bourland, Christina K Cramer, Justin M. Napolitano, James D. Ververs
Affiliation: Wake Forest University School of Medicine
Abstract Preview: Purpose:
Brain metastases (BM) can be treated with linear accelerator (LINAC)-based stereotactic radiosurgery (SRS). Treatment planning for this modality has evolved over time; treatment plans typi...
Authors: John Byun, Steven D Chang, Mingli Chen, Cynthia Chuang, Xuejun Gu, Melanie Hayden Gephart, Yusuke Hori, Hao Jiang, Mahdieh Kazemimoghadam, Fred Lam, Gordon Li, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang, Qingying Wang, Zi Yang, Xianghua Ye, Kangning Zhang
Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Accurate prediction of pain relief is crucial in determining the clinical effectiveness of Stereotactic body radiotherapy (SBRT) regimen for spine metastases. We propose a deep-learning frame...
Authors: Nadège Anizan, David Broggio, Désirée Deandreis, Didier Franck, Camilo Garcia, Stéphanie Lamart, Sébastien Leygnac, Alexandre Pignard
Affiliation: Gustave Roussy, Service de Physique Médicale, Institut Bergonié, Service de Physique Médicale, Gustave Roussy, Service de Médecine Nucléaire, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS
Abstract Preview: Purpose: This work aimed at developing an innovative workflow for 177Lu-PSMA personalized dosimetry to lesions and organs at risk (OAR) simultaneously, considering the cross-irradiation from bone meta...
Authors: Ozan Cem Guler, William Silva Mendes, Sangbo Oh, Cem Onal, Lei Ren, Apurva Singh, Phuoc Tran
Affiliation: University of Maryland School of Medicine, Baskent University Faculty of Medicine, Department of Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: To predict metastasis-free survival (MFS) for patients with prostate adenocarcinoma treated with androgen deprivation therapy and external radiotherapy using clinical factors and radiomics ex...
Authors: Yukio Fujita, Syoma Ide, Kei Ito, Tomohiro Kajikawa, Satoshi Kito, Keiko Murofushi, Yujiro Nakajima, Yuhi Suda, Kentaro Taguchi, Naoki Tohyama, Fumiya Tsurumaki
Affiliation: Komazawa University Graduate School, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Department of Radiology, Kyoto Prefectural University of Medicine
Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) for spine metastases is more effective for pain relief and local control than conventional radiotherapy. However, it is associated with vertebral compres...
Authors: Lili Chen, Andy T. Clark, Dusica Cvetkovic, Chang Ming Charlie Ma, Dae-Myoung Yang
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Radiodynamic therapy (RDT) shows promise as a strategy to inhibit the metastasis of premetastatic small cell lung cancer (SCLC). This study evaluates the therapeutic effect of RDT in inhibiti...
Authors: Albert Admasu, Kayla Alfonso, Maria de la Luz De Ornelas, Nesrin Dogan, Eric Mellon, Yunze Yang
Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Rotational uncertainties in single-isocenter multi-target (SIMT) stereotactic radiosurgery (SRS) HyperArc treatments can cause additional target displacement, potentially degrading overall pl...
Authors: Tommaso Frigerio, Joshua Genender, John M. Hoffman, Catherine (Caffi) Meyer
Affiliation: UCLA, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose: Accurate bone marrow segmentation is required for bone marrow dosimetry to monitor for dangers in PSMA-Lu177 radioligand therapy. We introduce a hybrid (AI/semantic knowledge) segmentation pi...
Authors: Carl D. Elliston, Lawrence Koutcher, Michael J. Price, Adam C. Riegel, Michael B Sisti, Tony J.C. Wang, Andy (Yuanguang) Xu
Affiliation: Columbia University Irving Medical Center
Abstract Preview: Purpose: An inverse treatment planning software was recently introduced to Gamma Knife radiosurgery. The purpose of this study is to compare the plan quality of the Gamma Knife ”Lightning” with that o...
Authors: David L. Barbee, Jose R. Teruel Antolin, Jinyu Xue
Affiliation: NYU Langone Health
Abstract Preview: Purpose: This work introduces a method of regional dose evaluation of normal brain tissue using local target-specific evaluation and compares to global dose evaluation for linac-based single-isocenter...
Authors: Jeremy S. Bredfeldt, Benito De Celis Alonso, Braian Adair Maldonado Luna, Kevin M. Moerman, Gerardo Uriel Perez Rojas, René Eduardo Rodríguez-Pérez, Kamal Singhrao
Affiliation: Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, Department of Radiation Oncology, Brigham and Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, Department of Mechanical Engineering, University of Galway, Faculty of Physics and Mathematics, Benemérita Universidad Autónoma de Puebla
Abstract Preview: Purpose: Online adaptive radiotherapy replanning for single-isocenter bone cancer metastasis treatment reduces on-table treatment time and patient discomfort compared to the multi-isocenter standard-o...
Authors: Nuraddeen Nasiru Garba, Kalpana M Kanal, Abdullahi Mohammed, Rabiu Nasiru, Muhammad SHAFIU Shehu, Daniel Vergara, Joseph Everett Wishart
Affiliation: AHMADU BELLO UNIVERSITY, ZARIA, University of Washington
Abstract Preview: Purpose: To establish local Diagnostic Reference Levels (DRLs) for head and neck computed tomography (CT) exams in Abuja, Nigeria, and to investigate the performance of brain metastasis (BM) and brain...
Authors: Michael Evan Chaga, Timothy Chen, Shabbar Danish, Jesse Feng, Joseph Hanley, Georg A. Weidlich
Affiliation: Zap Surgical, Tenafly High School, Jersey Shore University Medical Center
Abstract Preview: Purpose: ZapMU is the first independent monitor unit check software freely available supporting ZAP-X. In this study, the validation of ZapMU for independent check of dose calculation is performed, ut...
Authors: William Amestoy, Carolina Benjamin, Markus Bredel, Rodrigo Delgadillo, Nesrin Dogan, Michael E Ivan, Ricardo J Komotar, Gregory J. Kubicek, Eric Mellon, Ivaylo B. Mihaylov, Maria Irene Monterroso, Raymond A. Schulz, Ashish Shah, Robert M Starke
Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center, Varian Medical Systems
Abstract Preview: Purpose: Stereotactic Radiosurgery (SRS) is a widely used treatment modality in radiation oncology, utilizing various technologies such as Gamma Knife (GK), Cyber Knife (CK) and Linac-based SRS with H...