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Results for "case rate": 146 found

A Dosimetric Study of Misconnection to Unloaded Needles in Interstitial HDR Brachytherapy

Authors: Shifeng Chen, Mariana Guerrero, Brian A. Hrycushko, Kai Huang, Kai Jiang, Narottam Lamichhane, Paul M. Medin, Elizabeth Nichols

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland Medical Center

Abstract Preview: Purpose: Unloaded needle catheters, if not handled properly, pose a risk for channel misconnection in interstitial high dose rate (iHDR) brachytherapy. This study aims to investigate the dosimetric im...

A Dual Energy CT-Guided Intelligent Radiation Therapy Platform

Authors: Jiayi Chen, Manju Liu, Ning Wen, Haoran Zhang, Yibin Zhang

Affiliation: Department of Radiation Oncology, Ruijin Hospital, Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Duke Kunshan University, Department of Radiation Oncology,Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

Abstract Preview: Purpose: This study introduces a novel Dual Energy CT (DECT)-Guided Intelligent Radiation Therapy (DEIT) platform designed to streamline and optimize the radiotherapy process. The DEIT system combines...

A Foundational Model for Medical Imaging Modality Translation in Head and Neck Radiotherapy

Authors: Jie Deng, Yunxiang Li, Xiao Liang, Weiguo Lu, Jiacheng Xie, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Recently, foundational models trained on large datasets have shown remarkable performance across various tasks. Developing a foundational model for medical image modality translation in head-...

A Monte Carlo Framework for Automated Quality Assurance of Dynamically Collimated Pencil Beam Scanning Clinical Treatment Deliveries

Authors: Laura Bennett, Wesley S. Culberson, Albert Du, Kevin J. Erhart, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake

Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care, .decimal

Abstract Preview: Purpose: To develop and experimentally validate a novel Monte Carlo (MC) framework designed to enable calculation-based quality assurance (QA) for collimated intensity modulated proton therapy treatme...

A Monte Carlo-Based Secondary Dose Verification Tool for Treatment Plans of Robotic Radiosurgery System

Authors: Chuxiong Ding, Xuejun Gu, Heejung Kim, Weiguo Lu, Yang Kyun Park, Yulong Yan

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: The purpose of this study was to develop and evaluate a Monte Carlo (MC) dose calculation software (DosemanCK) for secondary dose verification of CyberKnife (CK) treatment plans. Unlike tradi...

A New Voxel-Based Similarity Approach for Assessing Contour Similarity and Clinical Dosimetric Effect

Authors: Shari Damast, Svetlana Kuznetsova, Christopher J. Tien

Affiliation: Yale University School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: Current contour similarity evaluation approaches (Dice Similarity Coefficient, Mean Distance to Agreement) are limited to geometric agreement without assessment of ultimate dosimetric impact....

A New Way to Assess Dynamic Response of Centrally Located Lung Cancer (CLLC) to SBRT and Conventional Radiation Therapy (CRT)

Authors: Nina Burbure, Tawfik Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang

Affiliation: FCCC at Temple University Hospital, Dept. of Radiation Oncology, Fox Chase Cancer Center at Temple University Hospital

Abstract Preview: Purpose: Higher rates of local failures and toxicities challenged radiation therapy of centrally located lung cancer (CLLC). We assessed the treatment response by measuring the early changes of PET+ n...

A Window-Level Based Approach for Generating Missing Tissue in CT Scans Using a Transformer-Gan Model

Authors: Mojtaba Behzadipour, Siyong Kim, Mitchell Polizzi, Richard R. Wargo, Lulin Yuan

Affiliation: VCU Health - Department of Radiology, Virginia Commonwealth University

Abstract Preview: Purpose:
The purpose of this study is to develop a method for generating missing tissue in CT scans of patients with large body sizes, where the field of view (FOV) of the scanner fails to capture ...

AI Auto-Contouring for CT-Based High-Dose-Rate Interstitial Brachytherapy of Cervical Cancer: Implications for Organ-at-Risk (OAR) Contouring and Dosimetric Analysis

Authors: Indrin J. Chetty, Jing Cui, Mitchell Kamrava, Tiffany M. Phillips, Jennifer M. Steers, Brad Stiehl

Affiliation: Department of Radiation Oncology,Cedars-Sinai Medical Center, Cedars-Sinai Medical Center

Abstract Preview: Purpose: Auto-contouring for HDR interstitial brachytherapy can be confounded by large deformation in anatomy and image quality. Here we evaluated the performance of an AI-based auto-contouring softwa...

Adapting Newer Treatment Planning Strategy for Uveal Melanoma Cases Using Gamma Knife Radiosurgery

Authors: Deepak Agrawal, Subhash Gupta, Shashanksharad Kale, Gopishankar Natanasabapathi, Manoj Phalak, Dhanabalan Rajasekaran, Surendra Kumar Saini, Subramani Vellaiyan

Affiliation: All India Institute of Medical Sciences (AIIMS), All India Institute of Medical Sciences

Abstract Preview: Purpose:
To evaluate planning strategy for uveal melanoma tumor (UM) in gamma knife stereotactic radiosurgery (GKSRS) using Lightning inverse planning software for treatment planning.
Methods:

Adaptive Proton Flash Therapy through Iterative Modular Pin Recycling

Authors: Zachary Diamond, Pretesh Patel, Sibo Tian, Xiaofeng Yang, David Yu, Ahmal Jawad Zafar, Jun Zhou

Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose:
We propose a method to optimize adaptive proton FLASH therapy (ADP-FLASH) using modularized pin-ridge filters (pRFs) by recycling module pins from the initial plan, reducing pRF adjustment...

Adversarial Diffusion-Based Self-Supervised Learning for High-Resolution MR Imaging

Authors: Zachary Buchwald, Chih-Wei Chang, Zach Eidex, Richard L.J. Qiu, Mojtaba Safari, Shansong Wang, Xiaofeng Yang, David Yu

Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: MRI offers excellent soft tissue contrast for diagnosis and treatment but suffers from long acquisition times, causing patient discomfort and motion artifacts. To accelerate MRI, supervised d...

An Automated Solution to Staged Treatments for Arteriovenous Malformations in Gammaknife

Authors: Strahinja Stojadinovic, Robert Timmerman, Yulong Yan

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas Southwestern Medical Center, University of Texas Southwestern Medical Center

Abstract Preview: Purpose: Radiosurgery for large (>10cc) arteriovenous malformations (AVMs) poses significant challenges due to increased risks of complications and lower obliteration rates. To mitigate toxicity, larg...

An Automated Tool for the Categorization of a Clinical Database By Anatomic Region for Big Data Applications

Authors: Yasin Abdulkadir, Justin Hink, James M. Lamb, Jack Neylon

Affiliation: Department of Radiation Oncology, University of California, Los Angeles

Abstract Preview: Purpose: Curation remains a significant barrier to the use of ‘big data’ radiotherapy planning databases of 100,000 patients or more. Anatomic site of treatment is an important stratification for almo...

An Evaluation of an SRS Quality Assurance System for Complex Patient Plans.

Authors: John Bennet, Indrin J. Chetty, Tai H. Dou

Affiliation: Department of Radiation Oncology,Cedars Sinai Medical Center, Department of Radiation Oncology, Cedars Sinai Medical Center, Department of Radiation Oncology,Cedars-Sinai Medical Center

Abstract Preview: Purpose:
To investigate the effect of complexity of stereotactic radiosurgery (SRS) volumetric modulated arc therapy plans on gamma pass rates (GPR) using a novel high-resolution ion chamber array ...

An International Survey of High Dose Rate Brachytherapy Dosimetry Practices

Authors: Anna Becker, Tomislav Bokulic, Mauro Carrara, Krzysztof Chelminski, Larry A. DeWerd, Alexis Dimitriadis, Benjamin Kellogg, Malcolm R. McEwen, Zakithi L.M Msimang, Mark J. Rivard, Thorsten Sander, Thorsten Schneider, Jamema Swamidas, Egor Titovich, Paula Toroi, Carlos E. de Almeida, Jacco de Pooter, Liset de la Fuente Rosales, Deborah G. van der Merwe

Affiliation: Radiation and Nuclear Safety Authority, University of Zagreb, National Physical Laboratory, IAEA, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Rio de Janeiro State University, Dosimetry Laboratory, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, Physikalisch-Technische Bundesanstalt, National Metrology Institute, University of the Witwatersrand, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, National Research Council, Warren Alpert Medical School of Brown University

Abstract Preview: Purpose: The recently published IAEA-TRS-492 international code of practice (CoP) aims at improving traceability, accuracy, and consistency in Brachytherapy Dosimetry. To assess current approaches to ...

Analytical Approach to Calculate Normal Tissue Complication Probability and Tumor Control Probability for Ultra-High Dose Rate Radiation (FLASH) Based on Linear-Quadratic Model

Authors: Santosh K. Agarwalla, Nrusingh C. Biswal, Shree C, Harikrishnan Suresh Kumar, Jajati K. Nayak, Prema P., Sarath K S, Tamil Selvan S, Hem D. Shukla

Affiliation: Variable Energy Cyclotron Centre, Department of Physics, Fakir Mohan University, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Sciences, Amrita Vishwa Vidyapeetham

Abstract Preview: Purpose: The rapid oxygen depletion in tissues during irradiation is the most accepted mechanism of the FLASH effect. However, the Normal Tissue Complication Probability (NTCP) and Tumor Control Proba...

Analyzer-Less X-Ray Interferometry with Super-Resolution Methods

Authors: Joyoni Dey, Hunter Cole Meyer, Murtuza Taqi

Affiliation: Louisiana State University

Abstract Preview: Purpose: We propose using super-resolution methods for X-ray grating interferometry without an analyzer with detectors that fail to meet the Nyquist sampling rate needed for traditional image recovery...

Auto-Contouring of OAR Enhances Patient Safety and Workflow in Gamma Knife Stereotactic Radiosurgery

Authors: Sven Ferguson, S. Murty Goddu, Ana Heermann, Taeho Kim, Nels C. Knutson, Hugh HC Lee, Shanti Marasini, Timothy Mitchell, Seungjong Oh, Kevin Renick

Affiliation: Washington University in St. Louis School of Medicine, Washington University School of Medicine in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis

Abstract Preview: Purpose: In the Gamma Knife stereotactic radiosurgery (GK-SRS), the delineation of organs-at-risks (OARs) was not fully automated. Due to the cumbersome nature of manual OAR contouring, dose evaluatio...

Automated Framework for Predicting Tumour Growth in Vestibular Schwannomas Using Contrast-Enhanced T1-Weighted MRI

Authors: Mehdi Amini, Minerva Becker, Simina Chiriac, Alexandre Cusin, Dimitrios Daskalou, Ghasem Hajianfar, Sophie Neveu, Marcella Pucci, Yazdan Salimi, Pascal Senn, Habib Zaidi

Affiliation: Geneva University Hospital, Division of Radiology, Diagnostic Department, Geneva University Hospitals, Service of Otorhinolaryngology-Head and Neck Surgery, Department of Clinical Neurosciences, Geneva University Hospitals

Abstract Preview: Purpose: Personalized prediction of vestibular schwannoma (VS) tumour growth is crucial for guiding patient management decisions toward observation versus intervention. This study proposes an automate...

Automated Parametric Custom Collimator Creation for Preclinical Irradiation Studies

Authors: Muhammad Ramish Ashraf, Dixin Chen, Lloyd Emmanuel Kamole Ghomsi, Edward Elliot Graves, Billy W Loo, Stavros Melemenidis, Joseph B. Schulz, Lawrie Skinner

Affiliation: Department of Radiation Oncology, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Precise beam collimation is essential in preclinical radiotherapy studies to ensure accurate dose delivery. Manual design and fabrication of organ-specific collimators usually consist of mult...

Automated Tool for Radiotherapy Initial Patient Setup: A Robust Approach Based on Vertebral Identification

Authors: Hailun Pan, Yingli Yang, Jie Zhang, Yibin Zhang

Affiliation: Department of Radiation Oncology,Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Department of Radiology, Ruijin Hospital, Department of Radiation Oncology, Ruijin Hospital, , Shanghai Jiaotong University School Of Medicine, Shanghai United imaging Healthcare Advanced Technology Research Institute

Abstract Preview: Purpose: Accurate patient positioning is critical in radiotherapy (RT) to ensure effective treatment delivery and minimize harming surrounding healthy tissues. Vertebral misalignment during RT setup h...

Automated Treatment Planning for Linac-Based Stereotactic Radiosurgery of Intraocular Malignancies Via Hyperarc Knowledge-Based Planning

Authors: Chase Cochran, Shane McCarthy, Damodar Pokhrel, William St Clair

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine

Abstract Preview: Purpose: Manually generating intraocular stereotactic radiosurgery (SRS) plans involves significant challenges, including lengthy planning times and inter-planner variability. Knowledge-based SRS plan...

BEST IN PHYSICS MULTI-DISCIPLINARY: Building a Cross-Modality Model to Integrate Bio-Clinical Features, Anatomical MRI, and White-Matter Pathlength Mapping for Personalized Glioblastoma RT Planning

Authors: Steve Braunstein, Angela Jakary, Hui Lin, Bo Liu, Janine Lupo, Tiffany Ngan, Ke Sheng, Nate Tran

Affiliation: Radiation Oncology, University of California San Francisco, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, University of California San Francisco, Department of Radiology and Biomedical Imaging, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose: Current RT clinical target volumes (CTVs) for Glioblastoma (GBM) employ 2cm isotropic expansions of gross tumor volumes. However, studies showed patients still experience progression beyond t...

Best- and Worst-Case Scenario: Uncertainty Bounds Informed By Daily Scanning in Weekly CBCT-Based Accumulated Dose for Head and Neck Cancer

Authors: Peter Balter, Kristy K. Brock, Clifton David Fuller, Tze Yee Lim, James Long, Brigid A. McDonald, Androniki Mitrou, Andrew J. Schaefer, Stina Svensson

Affiliation: The University of Texas MD Anderson Cancer Center, RaySearch Laboratories, Rice University, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences

Abstract Preview: Purpose: CBCT-based accumulated dose can provide up-to-date dose information on responding anatomy. To optimize resources, it is necessary to determine how many scans provide adequate information for ...

Big Data in-Vivo Epid Image Prediction for VMAT Radiotherapy

Authors: Casey E. Bojechko, Lance C Moore

Affiliation: University of California, San Diego, University of California San Diego

Abstract Preview: Purpose: EPID images collected during treatment can serve as an in-vivo error detection mechanism. Previous works have shown that comparing in-vivo EPID images to AI-predicted EPID images for IMRT pla...

Biokinetic Modeling and Dosimetry of Radiopharmaceutical Extravasation in Lu-177-PSMA Therapy for Metastatic Castration-Resistant Prostate Cancer

Authors: Shaheen Dewji, Emmanuel Mate-Kole, Sergio F Ruiz, Chris C. Wang

Affiliation: Georgia Institute of Technology, Nuclear and Radiological Engineering and Medical Physics Programs, Georgia Institute of Technology

Abstract Preview: Purpose: Extravasations are clinical events when a substance is administered intravenously and the fluid starts to leak into surrounding tissue instead of the target vessel. In the case of radiopharma...

Brachify: An Open-Source 3D Modeling Solution for 3D Printable Cervical and Vaginal Cylindrical Templates

Authors: Michael Kudla, Stephanie Merkl

Affiliation: BC Cancer - Kelowna

Abstract Preview: Purpose: 3D modeling for 3D printed GYN high dose rate (HDR) brachytherapy templates can be a time-consuming, error-prone process. To simplify the creation these templates, a software application has ...

Brachyplancheck: An Independent Monte Carlo Dose Calculation Tool for Brachytherapy Using Egs_Brachy

Authors: Amy Tien Yee Chang, Chi Wai Cheung, Tin Lok Chiu, Chen-Yu Huang, Chi Wa Kong, Pei-Xiong Li, Pak Hang Nam, Bin Yang, Siu Ki Yu

Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital

Abstract Preview: Purpose: This study introduces BrachyPlanCheck, an independent Monte Carlo (MC)-based dose calculation tool for 192Ir brachytherapy retrospective study or algorithm commissioning.
Methods: BrachyPl...

Characterization of Commercially-Available Dosimeters and Prototype Diamond Detectors for Absolute Flash Dosimetry of Small-Field Pulsed Proton Beams

Authors: Ronald C Chen, Hao Gao, Nicolas Gerard, Harold Li, Yuting Lin, Jarrick Nys, Jufri Setianegara, Mark Szczepanski, Aoxiang Wang

Affiliation: 4Physikalisch-Technische Werkstätten (PTW), Department of Biomedical Engineering, Huazhong University of Science and Technology, Ion Beam Applications (IBA), Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: Modern synchrocyclotrons can produce magnetically-scanned protons at ultra-high dose-rates (FLASH). However, their pulsed nature leads to high doses-per-pulse (DPP) which can cause non-neglig...

Characterizing and Modeling Higher-Order Motions of Collimator Subsystem on a 60RPM Gantry Linac for Improved Small Target Dosimetry

Authors: David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Blake Gaderlund, Ray Yang

Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: To address the root cause of dosimetric discrepancy for small central targets (<2cm) especially sensitive to geometric alignment of beamlets, by modeling higher-order oscillations of the coll...

Clinical Implementation of Volumetric Modulated Arc Therapy (VMAT) for Total Body Irradiation (TBI) with Off-the-Shelf Tools

Authors: Kai-Cheng Chuang, Oana I. Craciunescu, Christopher Kelsey, Joseph Kowalski, Nicole Larrier, Xinyi Li, Sheridan G. Meltsner, Anna E. Rodrigues, Yang Sheng, Qiuwen Wu

Affiliation: Duke University, Duke University Medical Center

Abstract Preview: Purpose: To clinically implement a Volumetric Modulated Arc Therapy (VMAT) procedure for Total Body Irradiation (TBI) with off-the-shelf tools.
Methods: Patient is treated on linac couch with a hyb...

Clinical Implementation of a Film Based Psqa System for SBRT on a 1.5T MR-Linac

Authors: Dylan Yamabe Breitkreutz, Lee Chin, Brige P. Chugh, Mark D'Souza, Brian M. Keller, Anthony Kim, Michelle K. Nielsen, Arjun Sahgal

Affiliation: Sunnybrook Health Sciences Centre

Abstract Preview: Purpose: The Elekta Unity MR-linac delivers highly conformal SBRT treatments using IMRT. These treatment plans require patient-specific quality assurance (PSQA) measurements to detect discrepancies be...

Clinical Validation of AI-Driven Segmentation Model for Pediatric Craniospinal Irradiation: Marked Reduction in Contouring Time and Enhanced Workflow Efficiency

Authors: Alexander Choi, William Ross Green, Christine Hill-Kayser, Gary D. Kao, Michael LaRiviere, Rafe A. McBeth, Steven Philbrook

Affiliation: Department of Radiation Oncology, University of Pennsylvania

Abstract Preview: Purpose: To validate the potential of clinical deployment of an in-house AI-driven auto-segmentation tool for pediatric craniospinal irradiation (CSI) in proton therapy, with goals of reducing manual ...

Clinical Validation of Fully Automated Script for Plan Conversion between Linacs with Different Mlc Model

Authors: David L. Barbee, Paulina E. Galavis, Lena Adel Samad, Jose R. Teruel Antolin

Affiliation: NYU, NYU Langone Health

Abstract Preview: Purpose: To validate an automated script that converts treatment plans of varying Varian MLC models

Methods: A C# script was developed using the Eclipse Scripting API to convert treatment plans...

Commissioning Radcalc v7.3 with a Collapsed Cone Calculation Algorithm for 6X FFF and 10X FFF Energies

Authors: Maria Jose Almada, Carlos Bohorquez, Maximiliano Musso, Rosa Petit, Carlos Daniel Venencia, Lucy D. Wolfsberger

Affiliation: LAP, Instituto Zunino - Fundacion Marie Curie

Abstract Preview: Purpose:
PSQA is crucial in maintaining patient safety, typically depending on dosimetric measurements. However, advancements in computational technology have highlighted the growing significance o...

Comparison Analysis of Three Kind of Solutions for Head and Neck Cancer VMAT Verification

Authors: Wenwen Bai

Affiliation: The Fourth Hospital of Hebei Medical University

Abstract Preview: Purpose: To compare three kind of solutions (EDR2 Film, MatriXX, COMPASS) for VMA quality assurance at head and Neck in Monaco plannig system.
Methods: Monacao 5.1 planning system optimazed 10 case...

Comparison of CBCT Dose Calculation Accuracy between Truebeam Hypersight Image Reconstruction Algorithms

Authors: Sarah Aubert, Harald Keller, Jeff D. Winter

Affiliation: Princess Margaret Cancer Centre

Abstract Preview: Purpose: Support for treatment planning directly on CBCT imaging on C-arm linacs will enable adaptive radiation therapy (ART) capacity with increased treatment technique flexibility. The HyperSight im...

Comprehensive Analysis of Plan Modulation in SRS/SBRT Plans: A Single Institution Study of 461 Cases

Authors: Yunfeng Cui, Will Giles, Xinyi Li, Ke Lu, Jennifer C. O'Daniel, Anna E. Rodrigues, Chunhao Wang, Lana Wang, Yibo Xie, Sua Yoo, Jingtong Zhao

Affiliation: Duke University, Duke University Medical Center

Abstract Preview: Purpose:
To establish quantitative measurement of plan modulation for SRS/SBRT treated with Volumetric Modulated Arc Therapy (VMAT) on C-arm LINACs.
Methods:
A total of 461 plans were analyze...

Deep Learning-Based Multileaf Collimator Sequence Prediction for Automated VMAT Treatment Planning in Pancreatic Cancer

Authors: Zixu Guan, Takahiro Iwai, Takashi Mizowaki, Mitsuhiro Nakamura, Michio Yoshimura

Affiliation: Kyoto University, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University

Abstract Preview: Purpose:
The goal of this study is to develop a fully automated treatment planning approach for VMAT in pancreatic cancer that can convert patient anatomy into LINAC machine parameters. In this wor...

Deep Learning-Driven Comparative Analysis of CNN-Based Architectures and High-Order Vision Mamba U-Net (H-vMUNet) for MRI-Based Brain Tumor Segmentation

Authors: Sang Hee Ahn, Nalee Kim, Do Hoon Lim

Affiliation: Samsung Medical Center, Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine

Abstract Preview: Purpose: MRI offers superior soft-tissue contrast, aiding tumor localization and segmentation in radiation therapy, which traditionally relies on oncologists' expertise. This study compares CNN-based ...

Demographic Attributes of the Train-Test Sets and Their Impact on AI Performance: Medical Imaging Applications

Authors: Maryellen L. Giger, Fahd Hatoum, Robert Tomek, Heather M. Whitney

Affiliation: The University of Chicago

Abstract Preview: Purpose: To assess the importance of applying stratified sampling across demographic attributes (including age, sex, race, and ethnicity) when constructing training and testing datasets for ML-based d...

Development and Clinical Validation of Hyperarc Stereotactic Radiosurgery Method for Intraocular Tumors

Authors: Chase Cochran, Damodar Pokhrel, William St Clair

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine

Abstract Preview: Purpose: Currently, intraocular disease is primarily treated via COMS-plaques brachytherapy. Various stereotactic approaches via photons/proton beam have also been implemented (CyberKnife/GammaKnife/p...

Development and Evaluation of Aria Report-Based Initial Chart Check Tool

Authors: Ulrich Langner, Timothy Leech, Oleksii Semeniuk

Affiliation: Brown University Health

Abstract Preview: Purpose: To standardize and improve quality of the chart review process, while simultaneously increasing the efficiency of the physicist, by allowing them to allocate more time for other items.
Met...

Development and Experimental Validation of an in-House Proton Treatment Planning System with Energy Layer Optimization

Authors: Hao Gao, Yuting Lin, Jufri Setianegara, Aoxiang Wang, Peng Xiao, Qingguo Xie, Yanan Zhu

Affiliation: Department of Biomedical Engineering, Huazhong University of Science and Technology, Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: Intensity-modulated proton therapy (IMPT) achieves uniform tumor dose distribution while sparing organs-at-risk (OAR) by optimizing spot weights across energy layers. Accelerating IMPT delive...

Development and Validation of a Principal Component Analysis Statistical Shape Pediatric/Adolescent Breast Model for Pre-CT Era Breast Dose Reconstruction in Late Effect Studies of Female Childhood Cancer Survivors

Authors: Gregory T. Armstrong, James E. Bates, Kristy K. Brock, Laurence Edward Court, Matt Ehrhardt, Danielle Friedman, Aashish C. Gupta, Donald Hancock, Rebecca M. Howell, Cindy Im, Tera S Jones, Choonsik Lee, Wendy Leisenring, Taylor Meyers, Lindsay Morton, Chaya Moskowitz, Joe Neglia, Vikki Nolan, Caleb O'Connor, Kevin C. Oeffinger, Constance A. Owens, Arnold C. Paulino, Chelsea C. Pinnix, Sander Roberti, Cecile Ronckers, Susan A. Smith, Kumar Srivastava, Lucie Turcotte

Affiliation: Department of Medicine, Duke University School of Medicine, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, The University of Texas MD Anderson Cancer Center, Department of Oncology, St. Jude Children’s Research Hospital, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, Division of Pediatric Epidemiology and Clinical Research, University of Minnesota, Division of Childhood Cancer Epidemiology, University Medicine at Johannes Gutenberg University Mainz, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Pediatrics, University of Minnesota, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Biostatistics, St. Jude Children’s Research Hospital, Clinical Research Division, Fred Hutchinson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences

Abstract Preview: Purpose: To (1) develop and validate a novel anatomically realistic pediatric/adolescent population-based breast model, (2) incorporate model into an age-scalable female reference phantom, and (3) dem...

Development of Hybrid Shielding Collimator to Reduce Radiation Exposure in Fluoroscopy

Authors: Yona Choi, Kyo-tai Kim, Seungwoo Park, Dung Thi Tran

Affiliation: Gemss Health Care Inc,, Korea Institute of Radiological & Medical Sciences

Abstract Preview: Purpose: We developed shielding materials and a hybrid concept collimator for fluoroscopy to reduce the dose to normal tissues outside the treatment field, which are capable of quantifying dose rate a...

Development of Treatment Planning System for Carbon Ion Radiotherapy in Yonsei Cancer Center

Authors: Min Cheol Han, Chae-Seon Hong, Changhwan Kim, Dong Wook Kim, Hojin Kim, Jin Sung Kim, HO Lee, Sac Lee, Yongdo Yun

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine

Abstract Preview: Purpose: Carbon ion radiotherapy (CIRT) offers the advantage of a greater relative biological effectiveness (RBE) weighted dose, which must be integrated into the treatment planning system (TPS). This...

Development of an Inverse Treatment Planning System for Precision Small Animal Radiotherapy

Authors: Zihao Liu, Qiwei Wu, Yanfei Xiong, Yidong Yang, Ning Zhao

Affiliation: Department of Engineering and Applied Physics, School of Physical Sciences, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China

Abstract Preview: Purpose: To develop an inverse planning framework that optimizes beam angles and intensities for small animal radiotherapy and to validate its accuracy and effectiveness.
Methods: The inverse plann...

Direct-to-Unit Dose Calculations for Stereotactic Radiosurgery on a C-Arm Linac with Modern on-Board Imaging Solutions

Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Haley K Perlow, Alex T. Price, Atefeh Rezaei, Prashant Vempati, Runyon C. Woods

Affiliation: University Hospitals Seidman Cancer Center

Abstract Preview: Purpose: The HyperSight imaging feature on C-arm linacs(HS-CBCT) offers increased CT number accuracy over conventional on-board imaging. The C-arm geometry allows for noncoplanar treatments common to ...

Dose Reconstruction from Prompt-Gamma Imaging Towards Real-Time Adaptive Proton Therapy

Authors: Thomas R. Bortfeld, Prof. Elisabetta De Bernardi, Tianxue Du, Beatrice Foglia, Chiara Gianoli, Takamitsu Masuda, Katia Parodi, Marco Pinto, Boon-Keng Kevin Teo, Yunhe Xie

Affiliation: Department Of Radiation Oncology, Massachusetts General Hospital (MGH), School of Medicine and Surgery, University of Milano-Bicocca, Department of Medical Physics, Ludwig-Maximilians-Universität Mßnchen (LMU Munich), Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) Mßnchen, National Institutes for Quantum Science and Technology (QST), University of Pennsylvania, Department of Experimental Physics - Medical Physics, Ludwig-Maximilians-Universität (LMU) Mßnchen

Abstract Preview: Purpose: The full potential offered by protons in clinical practice is limited by range uncertainties. One possibility for monitoring is through secondary prompt gammas (PG). PG emission along the pen...

Dosex As a per-Pulse Uhdr and Conventional Electrometer Compatible with Sandard Clinical Probes

Authors: Petr Bruza, David J. Gladstone, Austin Sloop, Rongxiao Zhang

Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Health

Abstract Preview: Purpose: UHDR-specific probes are becoming available on the market but often demand high costs and long order times. The reduced sensitivity of these probes often imposes challenges when measuring con...

Dosimetric Analysis of Lymphopenia after Lung Irradiation and Modeling the Probability of Normal Tissue Complications

Authors: Tianyuan Dai, Xiaoying Fan, Shuting Wang, Yong Yin

Affiliation: Department of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences

Abstract Preview: Purpose: Decreased lymphocytes increase the risk of infections and other problems. Radiation exposure can cause the development of severe lymphopenia. In this study, we used a dynamic blood flow model...

Dosimetric Comparison of 6X and 10X Flattening Filter-Free Photon Beams on a Truebeam Linac Using the Eclipse TPS

Authors: Carlos E. Cardenas, Udbhav S. Ram, Marcin Wierzbicki

Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham, Juravinski Cancer Centre

Abstract Preview: Purpose:
This study aims to systematically evaluate the dosimetric properties and delivery efficiency of 6X-FFF and 10X-FFF beams for lung SBRT on the Varian TrueBeam STx using the Eclipse TPS 16.1...

Dosimetric Evaluation of Enhanced Dynamic Leaf Gap Modeling in Small-Field Clinical Plans: A Verification Study

Authors: Ian J. Butterwick, Sumudu Katugampola, ChangSeon Kim, Evan G. Meekins, Zhengdong Zhang

Affiliation: Mount Sinai Beth Israel, Gesinger Medical Center, Geisinger Medical Center

Abstract Preview: Purpose: To evaluate the dosimetric impact of enhanced dynamic leaf gap (EDLG) modeling in Eclipse V18.0 on small-field dosimetry within VMAT plans.
Methods: Plans with small fields (1 cm x 1 cm to...

Dosimetric Impact of Catheter Length Changes in HDR Brachytherapy for Accelerated Partial Breast Irradiation

Authors: Dylan Richeson, Dorin A. Todor

Affiliation: Inova Schar Cancer Institute, Virginia Commonwealth University

Abstract Preview: Purpose: High dose-rate (HDR) brachytherapy is prone to errors that can lead to incorrect dose delivery and potential medical events. One common issue is applicator length discrepancies, either due to...

Dynamic Winston-Lutz Testing for FFF Beams

Authors: Cambridge L Bui-Nguyen, Alexander S. Nguyen, Liqiang (Lee) Tao

Affiliation: Varian AOS @Epic Care, UC Berkeley

Abstract Preview: Purpose: Dynamic Winston-Lutz (WL) testing provides a comprehensive framework for evaluating the accuracy of isocenter alignment. This study investigates the impact of dynamic beam modulation, such as...

Early Imaging Identification of Osteoradionecrosis and Classification Using the Novel Clinrad System

Authors: Serageldin Attia, Zayne Belal, Cem Dede, Clifton David Fuller, Andrew Hope, Laia Humbert Vidan, Kate Hutcheson, Zaphanlene Kaffey, Stephen Y. Lai, Abdallah Mohamed, Amy Moreno, Jillian Rigert, Erin Watson

Affiliation: Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center; The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Princess Margaret Cancer Centre, University Health Network, 610 University Ave., The University of Texas MD Anderson Cancer Center, UT MD Anderson, Princess Margaret Cancer Centre, UT MD Anderson Cancer Center, Hospital of the University of Pennsylvania, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Head and Neck Surgery, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology

Abstract Preview: Purpose: Osteoradionecrosis (ORN) of the jaw is a debilitating radiation-induced toxicity lacking standardized classification criteria or treatment guidelines. Early identification of tissue injury co...

Evaluating Normal Tissue Toxicity Following Pulsed Low Dose Rate Radiotherapy

Authors: Shahabeddin mostafanazhad Aslmarand, Lili Chen, Dusica Cvetkovic, Troy A. Dos Santos, Chang Ming Charlie Ma, Dae-Myoung Yang

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose:
Pulsed low-dose-rate radiotherapy (PLDR) has been proposed to reduce normal tissue toxicity while maintaining tumor control comparable to conventional radiotherapy (CRT). This study assess...

Evaluating the Efficacy and Efficiency of Spine Treatment Using Diagnostic CT

Authors: Sunil Mani, Ilakiya Raghavendiran, Vasanthan Sakthivel, Skanda Kabilan Swamy

Affiliation: Edmond Santa Fe High School, Edmnd Deer Creek High, Cancer Specialists of North Florida, Advanced Medical Physics

Abstract Preview: Purpose: Purpose/Objective(s): To evaluate and validate the dose calculation and delivery accuracy for patients planned using diagnostic CT
Methods: A total of forty-two patients with palliative sp...

Evaluating the Performance and Limitations of an Automated Treatment Planning Tool for Intact Breast Radiotherapy across Diverse Patient Populations

Authors: Shatha Al Afifi, Hana Baroudi, Leonard Che Fru, Laurence Edward Court, Suzanne B. Evans, Kent A. Gifford, Adam D. Melancon, Melissa P. Mitchell, Issa Mohamad, Patricia Murina, Manickam Muruganandham, Tucker J. Netherton, Callistus M. Nguyen, Joshua S. Niedzielski, Deborah L. Schofield, Simona Shaitelman, Willie Shaw, Sanjay S. Shete, Adam Shulman, Brendon Smith, Sheeba Thengumpallil, Carlos Daniel Venencia, Conny Vrieling

Affiliation: University of Cape Town, MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, University of the Free State, UT MD Anderson Cancer Center, King Hussein Cancer Center, Instituto Zunino - Fundacion Marie Curie, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Dra., Hirslanden Clinique des Grangettes, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Therapeutic Radiology, Yale University School of Medicine, Yale University, The University of Texas, MD Anderson, Houston TX

Abstract Preview: Purpose:
Automated contouring and planning tools are usually trained on single-institution datasets, seldom tested across diverse patient populations. This introduces a risk of population bias, res...

Evaluation of Dose-Rate Metrics in Intensity Modulated Proton Therapy for Prostate Cancer Treatments

Authors: Stella Flampouri, Edgar Gelover, William Andrew LePain, Roelf L. Slopsema, Alexander Stanforth, Mingyao Zhu

Affiliation: Emory Healthcare, Emory University

Abstract Preview: Purpose: Little consideration was given to the change in dose rate (DR) observed when moving to pencil beam scanning (PBS). This study reports on DR in clinical prostate PBS plans. While dose distribu...

Evaluation of Four Different Dose Calculation Algorithms for Commissioning of a New Tyoe of Scanned Proton Therapy System

Authors: Nobukazu Fuwa, Masato Horita, Takahiro Kato, Ryo Tanokura, Yuki Tominaga

Affiliation: Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Central Japan International Medical Center, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University

Abstract Preview: Purpose:
We have installed a new type of scanned proton therapy system (Varian ProBeam 360°TM). This study aimed to evaluate the four different dose calculation algorithms.
Methods:
Sixteen b...

Evaluation of a Commercially Available Solution for Dose Verification Using Daily AI Generated Pseudo-CT from CBCT.

Authors: Chloe DiTusa, Panayiotis Mavroidis, Christopher W. Schneider, Sotirios Stathakis

Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center, University of North Carolina

Abstract Preview: Purpose: To evaluate and compare dose calculation differences between Monaco and AdaptBox by TheraPanacea on AI-generated pseudo-CTs (pCTs) from a CBCT.

Methods: Dose calculations in water phan...

Evaluation of the Inverse Planning Optimization with Leksell GammaplanÂŽ

Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang

Affiliation: FCCC at Temple University Hospital

Abstract Preview: Purpose: Our GammaKnife(GK) has been upgraded from 4C to ICON recently. In this study we evaluated the performance of Lightning IPO for ICON.
Methods: 10 cases with single brain metastasis previous...

Explainable Hybrid CNN-LLM Model to Guide Treatment Planning of Cervical Cancer High Dose Rate Brachytherapy

Authors: Adnan Jafar, Xun Jia, Michael B. Roumeliotis

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University

Abstract Preview: Purpose: HDR brachytherapy (HDRBT) treatment planning is challenging due to the need for high-quality plans under time pressure, considering anatomy and applicator geometry. This study proposes an exp...

Fast Synthetic-CT-Free Dose Calculation in MR Guided RT

Authors: Claus Belka, Stefanie Corradini, George Dedes, Nikolaos Delopoulos, Christopher Kurz, Guillaume Landry, Ahmad Neishabouri, Domagoj Radonic, Adrian Thummerer, Niklas Wahl, Fan Xiao

Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, LMU Munich, Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), National Center for Radiation Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO)

Abstract Preview: Purpose: In MR-guided online adaptive radiotherapy, MRI lacks tissue attenuation information necessary for accurate dose calculations. Instead of using deep learning methods to generate synthetic CT i...

Feasibility of Commercial Independent-Dose-Calculation for Pencil-Beam-Scanning Proton Therapy

Authors: Wen C. Hsi, Kayla Schneider

Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences

Abstract Preview: Purpose:
Measurement-based patient-specific quality-assurance (PSQA) conducted with a 2D dosimeter to verify delivered dose of each field over 3 measurement-depths is time-consuming with limited se...

First Phantom Testing of Biology-Guided Radiotherapy for Sequential Integrated Boost Radiotherapy

Authors: Girish Bal, David J. Carlson, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Henry S. Park

Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: This study explores the feasibility, accuracy, and dosimetric performance of hybrid biology-guided radiotherapy (BgRT) combined with image-guided radiotherapy (IGRT) for delivering sequential...

From Prediction to Practice: Performance of a Deep Learning-Based Breast Planning Algorithm

Authors: Thomas L. Hayes, Nicholas C. Koch, Han Liu, Qingyang (Grace) Shang, Benjamin J. Sintay, Caroline Vanderstraeten, David B. Wiant

Affiliation: Fuse Oncology, Cone Health, Cone Health Cancer Center

Abstract Preview: Purpose:
This study evaluates the accuracy of a deep learning-based automatic breast planning script in predicting beam energy for breast cancer treatments. The script was validated and implemented...

Hydrated Electron Yield Under Electron Irradiation at Ultra-High Dose Rates with Varying Physical Beam Parameters

Authors: Xu Cao, Wesley S. Culberson, Aubrey Parks, Brian W Pogue, Matthew Reed, William Scott Thomas

Affiliation: University of Wisconsin: Madison, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison

Abstract Preview: Purpose: Under Ultra-High Dose Rate (UHDR) irradiation, radical-radical interactions are likely enhanced due higher density production in time and space and this alters the cascade of reactions that s...

Image Guidance for Mitigating the Impact of Table Walkout on Delivered Dose in Non-Coplanar Stereotactic Radiotherapy

Authors: William E Burrell, Philip F. Durham, Anne N Hubbard, Yohan Akeakamai Walter, Hsinshun Terry Wu

Affiliation: Willis Knighton Cancer Center

Abstract Preview: Purpose: Linear accelerator (LINAC)-based single-isocenter, multi-target (SIMT) treatment has streamlined the stereotactic radiosurgery (SRS) workflow. However, off-isocenter treatment carries multipl...

Impact of IMRT Beam Scatter and Electronic Noise on Real-Time Kv and Fluoroscopy Image Quality

Authors: Wei Luo, Cameron Thayer-Freeman, Yifeng Zhao

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky

Abstract Preview: Purpose: Real-time Kilovoltage (kV) imaging has emerged as a powerful clinical aid, providing high-precision localization of moving targets during treatment. However, the Megavoltage (MV) treatment be...

Implementation of an Innovative Digital Competency Record System

Authors: Benjamin J. Sintay, Caroline Vanderstraeten, David B. Wiant

Affiliation: Fuse Oncology, Cone Health

Abstract Preview: Purpose: The Joint Commission (JC) mandates that healthcare organizations establish and evaluate staff competencies to ensure safe and effective patient care. In the context of increasing sub-speciali...

Improve the Risk Prediction of Radiation-Induced Esophagitis in Lung IMRT By an Anisotropic Dose Convolution Neural Network

Authors: Ibtisam Almajnooni, Elisabeth Weiss, Lulin Yuan

Affiliation: Virginia Commonwealth University

Abstract Preview: Purpose: We developed a deep learning neural network (DLNN) to predict the risk of radiation-induced esophagitis (RE) during lung cancer radiation therapy based on the spatial dose distribution, for t...

Integrated Catheter Position and Dwell Time Optimization for Focal Dose Escalation in Prostate HDR Brachytherapy

Authors: Bryan Bednarz, John M. Floberg, Joseph B. Schulz, Jordan M. Slagowski

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Catheter placement for high-dose-rate brachytherapy (HDR BT) is clinician dependent and potentially suboptimal for delivering simultaneous integrated boosts to intraprostatic gross tumor volu...

Interplay of Relative Biological Effectiveness and Dose Rate in Eye Plaque Brachytherapy with Low Energy Photons

Authors: Alexei V. Chvetsov, Sunan Cui, Sunyoung Jang, Robert D. Stewart

Affiliation: University of Washington and Fred Hutchinson Cancer Center, Penn State College of Medicine, University of Washington

Abstract Preview: Purpose: To evaluate spatial variation of relative biological effectiveness (RBE) in COMS (Collaborative Ocular Melanoma Study) eye plaques with low energy 125I and 103Pd photon sources as a function ...

Introduce a Novel Spot-Scanning Proton Arc(SPArc) Optimization Algorithm for Single Energy Extraction(SEE) Synchrotron-Accelerator-Based Proton Therapy System (PTS)

Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Jiajian Shen

Affiliation: Department of Radiation Oncology, Mayo Clinic, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital

Abstract Preview: Purpose: This study aims to develop the first SPArc optimization algorithm based on the Dynamic Programming (SPArc-DP), to improve the treatment delivery efficiency for synchrotron-accelerator-based P...

Investigating the Effect of Beam Flattening Filter on Dose Estimated with Varian’s Original and Enhanced Mlc Models

Authors: Kenny Guida, Hongyu Jiang, Harold Li, Hem Bahadur Moktan Tamang

Affiliation: University of Nebraska Medical Center, Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: Varian Eclipse v18.0 introduced Enhanced Leaf Model (ELM) of MLC, which provides better dose calculation accuracy than original DLG-based MLC model. The leaf-gap (LG) parameter for ELM repres...

Investigation of the Impact of Dlg Changes on Plan Quality and Patient Specific QA

Authors: Nicole C. Detorie, Steven M. Kirsner, Remy Y. Manigold

Affiliation: Scripps Cancer Center

Abstract Preview: Purpose:
Dosimetric Leaf Gap (DLG) is an important factor in obtaining the proper beam model in the Eclipse treatment planning system. The purpose of this study was to investigate the dosimetric im...

Investigation on Quantifying Chemical Species Post Electron and Proton Irradiation Using the Geant4-DNA 'UHDR' Example

Authors: Konstantinos Chatzipapas, George C. Kagadis, Panagiotis Konstas, Dimitris N. Mihailidis, Dimitris Visvikis

Affiliation: LaTIM, INSERM UMR1101, University of Pennsylvania, LaTIM, INSERM, University of Brest, University of Patras

Abstract Preview: Purpose: This study investigates the temporal evolution of radiolytic species (H3O+, OH•, OH-) in water under electron and proton irradiation using the mesoscopic chemistry model that allows longer te...

Is Your Resident Ready to Become a Brachytherapy Physicist? a Training Exercise and Evaluation Tool in HDR Brachytherapy Planning Errors

Authors: Amar K. Basavatia, Lee C. Goddard, Wolfgang A. TomĂŠ, Christian Velten, Ping Yan, Ravindra Yaparpalvi, Maria Stefania diMayorca

Affiliation: Montefiore Medical Center

Abstract Preview: Purpose: High dose rate (HDR) brachytherapy planning is a high-risk procedure performed under significant time pressure, with human failure being the leading cause of error. To elevate training for me...

Joint Optimization of Patient-Specific Range Modulators and Beam Intensities for Conformal Flash Proton Therapy

Authors: Hao Gao, Jiayue Han, Wangyao Li, Yuting Lin, Jufri Setianegara, Aoxiang Wang, Yanan Zhu

Affiliation: Department of Biomedical Engineering, Huazhong University of Science and Technology, Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: Proton therapy leverages Bragg-peak-based dose delivery to achieve ultra-high-dose-rate FLASH with patient-specific range modulators (PSRM). Current proton FLASH (pFLASH) planning typically i...

Knowledge-Based Planning in Proton Therapy: Validation and Model Size Considerations with Limited Data

Authors: Gregory A Azzam, Michael Butkus, Nesrin Dogan, Robert Kaderka, Nhan Vu, Yihang Xu

Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center, University of Miami, Sylvester Comprehensive Cancer Center

Abstract Preview: Purpose: Knowledge-based planning (KBP) has demonstrated potential for improving planning quality and efficiency. Adoption of KBP in particle therapy has been slow due to limited number of plans to tr...

Knowledge-Based Three-Dimensional Dose Prediction for High Dose Rate Prostate Brachytherapy

Authors: Mojtaba Behzadipour, Suman Gautam, Tianjun Ma, Ikchit Singh Sangha, Bongyong Song, William Song, Kumari Sunidhi

Affiliation: UC San Diego, Virginia Commonwealth University

Abstract Preview: Purpose: This study aims to develop a knowledge-based voxel-wise dose prediction system using a convolutional neural network (CNN) for high-dose-rate (HDR) prostate brachytherapy and to evaluate its p...

Learning from Failures – Case Studies into Failing Patient Specific Quality Assurance Plans

Authors: Christopher S. Melhus, Elizabeth Meyer, Cassandra Stambaugh

Affiliation: Tufts Medical Center

Abstract Preview: Purpose: To investigate the clinical treatment planning parameters that impact patient-specific quality assurance (PSQA) passing rates for hippocampal avoidance whole brain (HAWB) treatment plans.
...

Log-Based Predictive Modeling of the Dynamic Collimation System (DCS) Trimmer Dynamics for Efficient Proton Pbs Delivery

Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake

Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care

Abstract Preview: Purpose: To develop an accurate predictive temporal model for the movement of Dynamic Collimation System (DCS) trimmers during collimated proton pencil beam scanning (PBS) deliveries using log data. T...

Lymphocytic Feature Characterization Using a Deep Learning Algorithm on Post-Radiation Lymph Nodes

Authors: Rico Castillo, Katherine Gonzalez, Casey C. Heirman, Kyle J. Lafata, Casey Y. Lee, Xiang Li, Yvonne M Mowery, Yvonne M Mowery, Daniel Murphy, Allison Pittman, Ashlyn G. Rickard

Affiliation: Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh

Abstract Preview: Purpose: To evaluate the ability of a deep learning model to identify pathomic features in lymph nodes of preclinical head and neck squamous cell carcinoma (HNSCC) models as surrogates for predicting ...

MC-Dolce: Monte Carlo-Based System for Dose and Linear Energy Transfer Calculations Engine for Carbon-Ion Radiotherapy

Authors: Min Cheol Han, Jin Sung Kim, Seok Ho Lee, Gahee Son, Yongdo Yun

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Hanyang University, Department of Integrative Medicine, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine

Abstract Preview: Purpose: This study aims to develop the MC-DOLCE, a Monte Carlo (MC)-based system capable of calculating physical and biological dose distributions, as well as linear energy transfer (LET) distributio...

Maximum Conformity IMPT Planning with the Dynamic Collimation System

Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake

Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Iowa, Iowa Health Care

Abstract Preview: Purpose:
To perform end-to-end treatment planning and delivery verification of energy-specific collimated treatments optimized to achieve the maximum obtainable high-dose conformity using the dynam...

Mitigating Discrepancies in Radiology Reports: A Robust LLM Approach for Generating Consistent Impressions

Authors: Junwen Liu, Mengzhen Wang, Ning Wen, Jifeng Xiao, Fuhua Yan, Yanzhao Yang, Xuekun Zhang, Zheyu Zhang

Affiliation: Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai Jiaotong University, The SJTU-Ruijin-UIH Institute for Medical Imaging Technology, Shanghai Jiaotong University Schoo of Medicine

Abstract Preview: Purpose:This study aims to develop and evaluate a large language model (LLM) fine-tuned to generate consistent and accurate impressions from imaging findings. Additionally, the study investigates the ...

Monte Carlo Evaluation of Water-Equivalent Materials for Nanowire-Based Oslds in Flash Radiotherapy

Authors: James Chun Lam Chow, Harry E Ruda

Affiliation: University of Toronto, Princess Margaret Cancer Centre

Abstract Preview: Purpose: FLASH radiotherapy (FLASH-RT) with dose rate greater than 40 Gy/s, has demonstrated potential in reducing normal tissue toxicity while maintaining tumor control. However, accurate and reliabl...

Multi-Modality Artificial Intelligence for Involved-Site Radiation Therapy: Clinical Target Volume Delineation in High-Risk Pediatric Hodgkin Lymphoma

Authors: Tyler J Bradshaw, Sharon M Castellino, Steve Y Cho, David Hodgson, Bradford S Hoppe, Kara M Kelly, Andrea Lo, Sarah Milgrom, Xin Tie

Affiliation: Department of Radiation Oncology, University of Toronto, Department of Radiology, University of Wisconsin, University of Colorado Anschutz, Department of Medical Physics, University of Wisconsin, Department of Radiation Oncology, Mayo Clinic, Department of Radiation Oncology, BC Cancer, Vancouver Center, Department of Radiology, University of Wisconsin - Madison, Roswell Park Comprehensive Cancer Center, Emory University School of Medicine

Abstract Preview: Purpose: Clinical target volume (CTV) delineation for involved-site radiation therapy (ISRT) in Hodgkin lymphoma (HL) is time-consuming due to the need to analyze multi-time-point PET/CT scans co-regi...

Multi-Vendor Validation of a Deep Learning-Based Synthetic CT Generation Model for MR-Only Radiotherapy Planning in the Pelvis

Authors: Gregory Bolard, Rabten Datsang, Sarah Ghandour, Timo Kiljunen, Pauliina Paavilainen, Sami Suilamo, Katlin Tiigi

Affiliation: Turku University Hospital, Virginia Commonwealth University, MVision AI, North Estonia Medical Centre, Docrates Cancer Center, Hopital Riviera-Chablais

Abstract Preview: Purpose: To verify the performance of a vendor-neutral deep learning model for synthetic CT generation from T2-weighted and balanced steady-state MR sequences to support both MR-only simulation and MR...

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Authors: Houssam Abou Mourad, Christopher Ackerman, Stephen Adler, Kirk Aduddell, Muhammad K. Afghan, Hamid G. Aghdam, Diego Aguilar, Kang-Hyun Ahn, Francis Ai, Hua Ai, Ray Anthony Aikens, Manik Aima, Victoria Ainsworth, Erfan Akbari, Blessing Akinro, Rani Al-Senan, Khalid Alabbasi, Sam Alam, Daniel Alexander, Mohammed H. Aljallad, Mazin T. Alkhafaji, Ahmad K. Alkhatib, Scott J. Alleman, James Logan Allen, Ibtisam Almajnooni, Tiba Alnaqshabandi, Murat Alp, Stephen J. Amadon, Riska Amilia, Ala Amini, Shiho Amster, Mason R. Anders, Erin Angel, Ledi Anggara, John A. Antolak, Debora Antonio, Felicity Appiah, Haiqa Arain, Lahcen Arhjoul, Ali V. Aritkan, Muhammad Arshad, Mark E. Artz, Nathan S. Artz, Frank A Ascoli, John R. Ashburn, Benjamin Astarita, Masakazu Atsumi, Rex G. Ayers, Tara M. Bachman, Nina L. Bahar, Bing Bai, Michael J. Bailey, Chris Baird, Mohammad Bakhtiari, Andrew J. Ballesio, Isabel Balvoa, Qinan Bao, Jeffrey J. Barbarits, Joseph Barbiere, Philip C. Bardos, Gary T. Barnes, John C. Barrett, Divya Bartley, Steven J. Bartolac, Robert Barton, Christopher P. Bass, Loni Bates, Alan Baydush, John E. Bayouth, Stephen Beach, Kevin Beaudette, Kaelyn Becker, Natalie A. Beckmann, Colleen Beer, Sepideh Behinaein, Jake M. Bell, David M. Bellezza, Maria R. Bellon, Ahmed Benelfassi, Stephanie Louise Bennett, Todd Bernath, Kate Bevins, Nicholas B. Bevins, Brian J. Bismack, David Blaich, Anthony P. Blatnica, Joseph W. Blickenstaff, Steven Blum, Maggie Bobbett, Dayna Bodensteiner, Daniel Boedeker, Robert C. Boggs, Jason D. Bond, Sjirk N. Boon, Jennifer M. Borsavage, Ryan J. Bosca-Harasim, Ryan J. Bosca-Harasim, Satya R. Bose, Todd Bossenberger, Cristina Boswell, Djamal Boukerroui, Christopher M. Bowen, Aaron Brammer, Rich Brancaleoone, Eric Brass, Luis Bravo, William Breeden, Christina Breeze, Eric E. Brost, Justin L. Brown, Karen L. Brown, Marissa Brown, Norman Lee Brown, Payton Brown, Patrick V. Brunick, Ryan Brunkhorst, Gwendolyn P. Brunner, Camelia E. Bunaciu, Maria Bunta, Olwen Burton, Karim Butalag, Priscilla F. Butler, Angela Cagwin, Jeffrey L. Campbell, Warren G. Campbell, Tyler Cantrell, Xu Cao, Yanan Cao, Peter F. Caracappa, Amanda M. Caringi, Joe Caron, Joshua Carter, Kenneth W. Cashon, Sarah Castillo, Everett Cavanaugh, Suran Chae, Abhi Chakrabarti, PhD, Philip Chan, Jina Chang, Sha X. Chang, Youssef M. Charara, Pierre E. Charpentier, Priyanka Chaudhary, Senthamil Selvan Chelliah, Chen Chen, Doris Chen, Kuan Ling Chen, Max Chen, Mingyue Chen, Mu Chen, Xinan Chen, Yie Chen, Yong Chen, Caroline Cheney, Shyh-Shi R. Chern, Stephen Thomas Chesser, Kin Man Cheung, Pai-Chun Melinda Chi, Yuwei Chi, Omar Chibani, Hung Ching, Gwi Ae Cho, Jongmin Cho, David Choi, Wing Yan Choi, Nitish Chopra, Daniel Christ, Olav I. Christianson, Emmanuel Christodoulou, Heeteak Chung, Sophia Claudio, Arely Clavel, William J. Clouse, Gilad Cohen, Michael S. Cohen, Vladimir Collantes, Jason Collier, Jacob Collins, Daria C. Comsa, Charles Conduah, Virgil N. Cooper, Anita M. Corrao, Frank D. Corwin, Mihaela Cosma, Ben Coull-Neveu, Mary K. Cox, Daniel F. Craft, Steven D. Crawford, Troy M. Crawford, Charles E. Creagh, Beatrice Croteau, Camille Crumbley, Wilbert F. Cruz, Guoqiang Cui, J. Adam M. Cunha, Scott Cupp, Bruce H. Curran, Jordan McCauley Cutsinger, Alita D Almeida, Harold DSouza, Nana Dabo-Akoteng, Robert Dahl, Shaun W. Dahl, Ghayath Dakkouri, Malek Daneshvarnezhad, Mylinh Dang, Matt Daniels, George M. Daskalov, David A. Davenport, Amanda Davidek, Scott E. Davidson, Maria De Ornelas, Dylan A. DeAngelis, Mike Deady, Daniel Dean, Savannah Decker, Savannah Decker, Michael Delafuente, Omer Demirkaya, Logan Dempsey, Marc Dennis, Viv Dennis, Dana Derby, Garron A. Deshazer, Veronique Destombes, Ajaya K. Devabhaktuni, Suneetha Devpura, James A. Deye, Shalmali Dharmadhikari, Dominic J. DiCostanzo, Richard V. DiPietro, Emily Diller, Lei Ding, Nayha V. Dixit, Charles Dodge, David N. Dodoo Amoo, Shana Donchatz, Lei Dong, Elangovan Doraisamy, Jennifer E. Dorand, Sarah Driver, Jiayi Du, Michael Duax, Ibrahim M. Duhaini, Ibrahim Duhaini, Kristen Duke, Richard Dunia, Leon Dunn, Shannon R. Durfee, Brittany Earl, Behzad Ebrahimi, Colton Eckert, Hisham Elasmar, John G. Eley, Abdelhamid Elfaham, David C. Ellerbusch, Scott J. Emerson, Sara Endo, David Erickson, Freddy Escorcia, Caroline Esposito, Patrice Essien, Adam Evearitt, Benjamin Fahimian, Liliosa C. Fajardo, Kevin Fallon, Guoqing Fan, Jiahua Fan, Mingdong Fan, Pei Fan, Bing Fang, Jian Fang, Yile Fang, Marc A. Felice, Ye Feng, Michele Sutton Ferenci, Philippe Feru, Jade Alecia Fischer, Aaron Fishbein, Caitlyn M. Fitzherbert, Damian Fondevila, Grant Fong, Robert Wesley Foster, Luke Fourie, Jeffrey Brian Fowlkes, Alexandre Franca Velo, D. Jay Freedman, Ronald W. Frick, Jie Fu, Samuel Fulton, Kamalakar Gaddam, Justin D. Gagneur, Mariana Gallo, Mariana Gallo, David Gammel, Robert G. Gandy, Junfang Gao, Yiming Gao, Victor L. Garcia, Michael Garcia-Alcoser, Jeffrey Garrett, Steven Anthony Gasiecki, Keith Gatermann, Avinash Gautam, Bhoj Gautam, Olivier Gayou, Andrew J. Gearhart, Paul B. Geis, Renil B. George, David P. Gierga, Robert Gilliam, James Giltz, Eric L. Gingold, Frederic Girard, Garth Gladfelder, Sharon Glaze, Brendan K. Glennon, Steven P. Glennon, Guy Godwin, David Lloyd Goff, Lisa M. Goggin, Daniel Goldberg-Zimring, Edward Joseph Goldschmidt, Ehsan Golkar, Angel Gomez, Jason Gong, Manish K. Goyal, Frank Graeff, Royce L. Gragg, Jonathan Gray, Alexander D. Green, Olga L. Green, Andrew Christopher Greene, Travis Greene, Jared Grice, Kevin T. Grizzard, Suveena Guglani, Jeffrey B. Guild, Patrick P. Guo, Sandesh Gupta, Megan Gute, Jonathan Ha, Rachael L. Hachadorian, Christopher Haddad, Lubomir Hadjiiski, Scott W. Hadley, Tomoe Hagio, Kelsey Hall, Logan P. Hall, Klaus A. Hamacher, Amineh Hamad Khatib, Amineh O. Hamad Khatib, Brian R. Hames, Carnell Hampton, Samuel S. Hancock, Robyn S. Handschuh, Jeremy Hansen, Paul Harden, Joseph Harms, Daniel P. Harrington, Carley Harris, Jamie Marie Harris, Jennifer Hart, Richard P. Harvey, Jeremy Hawk, Naoki Hayashi, Maria Laura Haye, Katherine Hazelwood, David Hearshen, Bret H. Heintz, Adam Henry, Frank William Hensley, Michael Chris Hermansen, Marissa Hernandez, Nadia Hernandez, Dayadna Hernandez Perez, Sarah Hetherington, Emily Hewson, Maynard High, Brian P. Hill, Charles B. Hill, Yunsil Ho, Simeon Hodges, David M. Hoeprich, Michael N. Hoff, Robert F. Hoffman, Russell Holden, Clay Holdsworth, Scott Hollingsworth, John R. Holmes, Steve Holmes, Neal S. Holter, Thomas M. Holtschneider, Amirul Hoque, Sabbir Hossain, Tyler S. Howlin, Andrew Robert Hoy, An Ting Hsia, Hao-Yun Hsu, David Hu, Tom C. Hu, Yu-Chi Hu, Long Huang, Mi Huang, Joshua Hubbell, Michael J. Huberts, Julie C. Hudson, Geoffrey Hugo, Donglai Huo, Justin D. Hurley, Martina H. Hurwitz, Mohammad NASEEM Hussain, Andrew Hwang, Ui-Jung Hwang, Joe Ianni, Geoffrey Ibbott, Khalil Ibrahim, Ileana Iftimia, Mohammad Islam, Oleksandra Ivashchenko, Keyvan Jabbari, Joshua Jackson, Joshua Jackson, Ferenc Jacso, Mary Ellen Jafari, Karim Jaffer, Amit Jain, Ngoneh Jallow, Sachin R. Jambawalikar, Joshua A. James, Sunyoung Jang, Desiree Jangha, Tomaj Javidtash, Jun-Hsuang Jen, Peter Jenkins, Todd P. Jenkins, Andrew R. Jensen, Mads Lykke Jensen, Hosang Jin, Bowen Jing, Danielle Marie Johnson, Joshua D. Johnson, Holly Johnston, Kevin Jones, Badal R. Juneja, Nikhil Sriram Kabilan, Robert Kaderka, Jaclyn Kain, Faraz Kalantari, Maduka M. Kaluarachchi, Ali Kamen, Amrit Kaphle, Alireza Kassaee, Saravjeet Kaur, Vaiva Kaveckyte, Linda A. Kelley, Katelyn Kelly, Kathryn Elise Bales Kelly, Delsin B. Khan, Om Khanal, Maksud Khatri, William Steadman Kiger, Bryan Kim, Jong Oh Kim, Sangroh Kim, Sophia Kim, Brian W. King, Erica Kinsey, Assen S. Kirov, Marc T. Kleiman, Matic Knap, Robert J. Kobistek, Inger-Karine Kolkman-Deurloo, Erika Kathryn Kollitz, Dramane Konate, Xiang Kong, Walter Kopecky, Sandra Kos, Nataliya Kovalchuk, Shane Krafft, James A. Kraus, Robert Krauss, Deae-eddine Krim, Serguei Kriminski, Kerry T. Krugh, Lichung Ku, Esra Kucukmokroc, Randi Kudner, Andrew T. Kuhls-Gilcrist, Antti Juhani Kulmala, Akila D. Kumarasiri, Zacariah E. Labby, Taylor Lackey, Edcer Jerecho Laguda, Thang Lam, Michael A. S. Lamba, Kara Lambson, Laurel Zenaida Larramendi, Andy D. Lau, Wolfram Laub, Tyler Laugh, Robert P. Laureckas, Donald Laury, Patricia Lavey, Ashlie Laydon, Adam LeVay, Brandon Lee, Brian Lee, Dong-Chang Lee, Ji Hyun Lee, Jui-Min Lee, Bryan Lemieux, Matthew Lesher, Nicole Leslie, Etienne Lessard, Trish Lewis, Alan Li, Alexander N. Li, Hui Li, Jenny Li, Jiaxin Li, Qiongge Li, Taoran Li, Xiang Li, Yanlong Li, Zisheng Li, Xing Liang, Yun Liang, Chien-Yi Liao, Karisa Liaw, Sung-Yen Lin, Tiffany Lin, Holly M. Lincoln, Lin Ling, Chang Liu, Shaohua Liu, Yu Liu, Chih-Ming Mark Lo, Eric Lobb, Dilson Lobo, Virginia L. Lockamy, Lauren C. Long, Nelia S. Long, Troy Long, Michele Loscocco, Thomas Lowinger, Cynthia Lu, Minghui Lu, Winnie Lu, Yonggang Lu, Jianqiao Luo, Pei-Chin Luo, Xuhan Luo, Jan Luse, Daniel A. Lutterman, Dang Hoang Oanh Luu, Yulia Lyatskaya, Trina Lynd, Morgan Cervo Lyon, Chi Ma, Jingfei Ma, Tianjun Ma, Laurie Madden, Gregory E. Madison, Kurt Maffei, Michael J. Maffett, Nyasha G. Maforo, Dennise Magill, Emma Magness, Alphonso W. Magri, Dennis Mah, Usman Mahmood, Rebecca N. Mahon, Courage Mahuvava, Andrew D. Maidment, Gerassimos M. Makrigiorgos, Harish K. Malhotra, Kate Mallory, P. Scott Mange, Vivek Maradia, Jacob Marasco, Camilla Marino, Loren R. Marous, Wagner Marques, Craig M. Marsden, Edward I. Marshall, Jonathan Marshall, Caroline Martel, Colin Martin, Alejandro Martinez, Jeffrey P. Masten, Richard Mathew, Bobby Mathews, Anetia S. Matthews Jackson, Matthew R. Maynard, Joel R. McAllister, Rafe McBeth, James A. McCulloch, Kiernan T. McCullough, Keelin McGee, Kiaran P. McGee, Brian M. McGill, Christopher M. McGuinness, Robert McKoy, Steven M. McQuiggan, Lacey Medlock, Chirag D. Mehta, Nancy Meiler, Robert Meiler, Matthew A. Meineke, Caroline Melancon, Daniel S. Meleason, Carolyn Meltzer, Chunhua Men, Stephanie Merkl, Michael Merrick, Keith A. Michel, Georgeta Mihai, Ana Mihail, Devin A. Miles, Edward J. Miller, Elizabeth A. Miller, Ronaldo Minniti, Linda Minor, Filmon Misgina, Ajeet Kumar Mishra, Chad Mitchell, Drew P. Mitchell, Gregory S. Mitchell, Jessica Mitchell, Jacqueline Moga, Uwe Mollenhauer, Julien-Fabrice Ngoune Momo, Emi Mondragon, Nicholas Mongillo, Victor J. Montemayor, Scott Montgomery, Diego Luis Montufar Hidalgo, Mohammadamin Moradi, Serban Morcovescu, Jill Anna Moreau, Terrance Moretti, Toby Morris, Courtney K. Morrison, Alexander Albert Morrow, Jill Moton, Jonathon Mueller, Reshma Munbodh, Daniel W. Mundy, Daniela Murgulet, Scott A. Murphy, Benjamin C. Musall, Jana E. Musgrove, Samantha Musial, Yong Hum Na, Joel Nace, Paul Naine, Justin Napolitano, Vrinda Narayana, Ganesh Narayanasamy, Moulay Ali Nassiri, Muhammad Naveed, Richard D. Nawfel, Ritish Nedunoori, Aaron Nelson, Kristin J. Nelson, Aaron Nelson, MD, Neerajan Nepal, Emily Neubauer Sugar, Shree Neupane, David Newey, Mark Newpower, Susan Ng, Bau H. Nguyen, Daniel J. Nicewonger, Xingyu Nie, Ethan Nikolau, Kevin D. Nitzling, Kai Niu, John M. Noll, Prashanth K. Nookala, Khalid Noori, James T. Norweck, Hamidreza Nourzadeh, Jessica L. Nute, Sebastiaan Nysten, Kevin OGrady, Ceferino Obcemea, Keith Ober, Jacqueline Ogburn, Timilehin Ogunbeku, Mina Okello, Brian Olson, Martin Keane Ongeti, Savannah Orrill, Joseph Ott, Bahadir Ozus, Jan Pachon, Alexis Paige-Glenn, Jason Paisley, Farideh Pak, Randahl C. Palmer, Kiran Pant, Virginia Pappas, Abby Pardes, So-Yeon Park, Alexis Parker, Karla Parker, Homayon Parsai, Tommy O. Parsons, Pankaj Patel, Amy Patrick, Johnlly G. Pattaserial, Lindsey M. Patton, Taylor J. Patton, Nava R. Paudel, Timothy John Paul, Colin Paulbeck, Olga V. Pen, Cheng Peng, Yuanlin Peng, Carmelo Perez, Dominik PeruĹĄko, Alexander Pevsner, Douglas Pfeiffer, Melanie Piantino, Daniel Piatigorski, Rajesh Pidikiti, Natalie Piechowska, Greg Pierce, Tina Pike, Donika Plyku, Robert Pohlman, Mariela Adelaida Porras-Chaverri, Subechhya Pradhan, Guillem Pratx, Chris Proctor, Alexander Pryanichnikov, Diane Pugel, Yue Qiu, Adam C. Quinton, Todd Racine, Andrea Radine, Dustin K. Ragan, Balasubramanian Rajagopalan, Kishore Rajendran, Eric V. Ramirez, Mehdi Ramshad, Vijay K. Rana, Brianne Raulston, Amy K. Readshaw, Hailey Reaux, Ian Reineck, Xuemin Ren, Meral L. Reyhan, Davenport Ria, Matthew J. Riblett, Kenneth M. Richardson, Rebecca F Richardson, Matthew Richeson, Ashlyn Rickard, Adam Riegel, Lynn N. Rill, Miguel A. Rios, E. Russell Ritenour, Scott P. Robertson, Marthony L. Robins, Rebecca Robinson Rey, Steve Rodney, Priscila Rodrigues, Edgardo Rodriguez, Tino Romaguera, Emilie Roncali, Joseph E. Roring, Alison R. Roth, Lawrence N. Rothenberg, Nick Rothwein, Kricia Emilia Ruano Espinoza, Damian DG Rudder, Donald R. Ruegsegger, Erwin W. Ruff, Brandon J. Russell, Frederick Rustad, Narayan Sahoo, Jonathan H. Saleeby, Habeeb H. Saleh, Flavio Salinas Aranda, Steffen Sammet, Daniel Sandoval, Aman Sangal, Joseph P. Santoro, MaĂ­ra Santos, Alexis Marie Sanwick, Milind Sardesai, Vikren Sarkar, Duminda Satharasinghe, Jessica L. Saunders, Carmen Sawyers, Sarah B. Scarboro, James Scheuermann, Colleen G. Schinkel, Dale Schippers, Joshua William Schlegel, David J. Schlesinger, Charles Ross Schmidtlein, Erich Schmitz, Jose Schneider, Erich A. Schnell, Lisa Schober, Leah Schubert, Michelle L. Schwer, James Seekamp, Jennifer Seger-Paisley, J. Anthony Seibert, Balaji Selvaraj, Raj N. Selvaraj, Meredith A. Semon-Pomposelli, Lasitha Senadheera, Naima Senhou, Christopher F. Serago, Hananiel Setiawan, Shakil B. Shafique, Aarti Shah, Hina Shah, Alok Shankar, Ryan Shanks, Kritika Sharma, Sunil K. Sharma, Jennifer M. Shealy, Ron Sheen, Gina L. Shelton, Mohammad Ullah Shemanto, Zion Sheng, Andrew J. Shepard, Justin R. Sherman, Kaizhong Shi, Xiaolin Shi, J. Allen Shih, Taciana Soares Shiue, Deborah J. Shumaker, Noah Silverberg, Ramon Alfredo C. Siochi, Amogh Sirniirkar, Marlene Skopec, Michael G. Skowronski, Dana Smetherman, Erika Smith, Eileen Sneeden, Jesse Snyder, James C. So, Emilie Soisson, Nima Soltani, Kwang Hyun Song, Liang Song, Xiaoling Song, Jigar B. Soni, Yashvant C. Soni, Jagadeesh R. Sonnad, Michael A. Speidel, Michael P. Speiser, James D. Speitel, Tanya Spellman, Joseph Patrick Speth, Daniel J. Spitznagel, Sara T. St. James, Alexander Stanforth, George Starkschall, James Stebelton, James P. Steinman, Jonathan M. Stenbeck, Robin L. Stern, Patrick D. Stevens, Erika Stewart, Gary Stinnett, Sarah A. Strand, Keith J. Strauss, Kristen Stryker, Edward Sudentas, Kevinraj N. Sukumar, Orhan H. Suleiman, John L. Sullivan, Paul Robert Sullivan, Mei Sun, Peng Sun, Kumari Sunidhi, Jacob Sunnerberg, Elizabeth A. Swanson, William J. Swanson, Larry E. Sweeney, Sean Swiedom, Gregory Szalkowski, Katsuyuki Taguchi, MohammadAli Tajik-Mansoury, Reza Taleei, Derek Tang, Shengzhang Tang, Mahin Tariq, Jason S. Tavel, Neelima Tellapragada, Alexandra Tellez, Dawn Tellez, Juan Manuel Tellez, Xiaokun Teng, James A. Terry, Biniam Tesfamicael, Confex Test, Aapm Tester, Contex Tester, Namita Thakur, David J. Theel, Kathleen D. Thomas, Emily A. Thompson, Stephen K. Thompson, Daniela Thorwarth, Kevin Tierney, Anders Tingberg, Ragu S. Tirukonda, Robert A. Tokarz, Robert J. Tokarz, Naresh B. Tolani, Brian Tom, Shidong Tong, Ebrahim Torangan, Martin Tornai, Diana Tovmasian, Trung Tran, Bryan Traughber, Samuel Trichter, Sugata Tripathi, Petra Trnkova, Panagiotis Tsiamas, Ryan Tsiao, Haifeng Tu, Philip N Tubiolo, Jeff D. Turley, Adam Turner, PhD, DABR, Conner Ubert, Chibueze Zimuzo Uche, Vincent M. Ulizio, Gnanaprakasam Vadivelu, Hema Vaithianathan, Sunil Valaparla, Fabiola Vallejo CastaĂąeda, Liesbeth Vancoillie, Matt Vanderhoek, Caroline Vanderstraeten, Nancy J. Vazquez, Linda A. Veldkamp, Trevor L. Vent, Anthony M. Ventura, Keith Ver Steeg, Irina Vergalasova, CHENG WANG, Christopher Waite-Jones, Matthew C. Walb, Reuben Waldron, Arlie Vester Walker, Jim Walsh, Alisa I. Walz-Flannigan, Cheng Wang, Helen H. Wang, Hui-Chuan Wang, Jiali Wang, Jian-xiong Wang, Kai Wang, Kyle Wang, Ning Wang, Yuntao Wang, Zhendong Wang, Zhixing Wang, Grace Ward, Sarah M. Way, Rachel L. Waymire, Melvin Weatherly, Charles Travis Webb, Lincoln J. Webb, Jia Wei, Wenbo Wei, Callie Weiant, Miriam S. Weiser, Eric M. Welch, Jered R Wells, Michelle C. Wells, S. Brock Westlund, Gerald A. White, John White, Darunee S. Whitt, David Wikler, Austin Wilkinson, Carly D. Williams, Mark Bennett Williams, Joshua M. Wilson, Keli C. Wilson, Nicholai Wingreen, Joseph Wishart, Alon Witztum, Katherine M. Woch Naheedy, Andy Wolf, Serkalem E. Wondimgezhu, Genevieve N. Wu, Wenhao Wu, Ye Wu, Yuxiang Xing, Li Xiong, Weijun Xiong, Xunyi Xu, Yan Xu, Tianyou Xue, Yanjie Xue, Girijesh K. Yadava, Derek Z. Yaldo, Kaiguo Yan, Yue Yan, Nathan E. Yanasak, Bowen Yang, Ray Yang, Xiaocheng Yang, Yun Yang, Yunze Yang, Bin Yao, Yuan (John) Yao, Anna N Yaroslavsky, Feng-Ju Yeh, Susanne Yerich, Michael V. Yester, Xiaofei Ying, Tekeste Yohannis, Tony Younes, Eyesha Younus, Jialu Yu, Justin Yu, Yan Yu, Pui Kuen Yuen, Joshua P. Yung, Steve Yuvan, Mehran Miron Zaini, Ramtin Zakikhani, Lee Anne Zarger, Merissa Zeman, Lisa Zent, Di Zhang, Dongqing Zhang, Hao Zhang, Jun Zhang, Lei Zhang, Lu Zhang, Maochen Zhang, Peng Zhang, Peng Zhang, Qingyun Zhang, Xin Zhang, Yi Zhang, Yinghui Zhang, Yongbin Zhang, Zhongwei Zhang, Bo Zhao, Xuandong Zhao, Yizhou Zhao, Weiping Zheng, Yi Zheng, Troy Zhou, Xiangzhi Zhou, Xiaohong Joe Zhou, Yuwei Zhou, Jin Zhu, Mingyao Zhu, Eric C. Zickgraf, John R. Zullo, Piotr Zygmanski, Leo van Battum

Affiliation: DTC Consultants, NL Health, Dartmouth Hitchcock Medical Center, ProCure Proton Therapy Center, Medical & Radiation Physics, Inc, Augusta University, Genesis Healthcare Partners, Michigan Medicine, Washington DC VA Medical Center, VA Medical Center, Mercy Southeast Hospital, Food And Drug Administration, University of Iowa, Advanced Radiation Physics Service, Inc, University of Pittsburgh, University of Wisconsin, Wellspan Health, Good Samaritan Hospital, Howard University Hospital, St. Mary's Memorial Health Center, Penn State Milton S. Hershey Med Ctr., New York Weill Cornell Medical Ctr, X-Ray Computations, Inc., US Navy, Penn State Health, Kelsey Seybold Clinic, Advocate Aurora, Fresno Cancer Center, Central Alabama Radiation Oncology, Riverside Methodist Hospital Ohio Health, Alliance Medical Physics, OCSRI, AAPM, University of Minnesota, University of Virginia Health System, PGIMER, Barrigel, Johns Hopkins Univ, Appex Physics Partners, BoxElder Research, University of Oklahoma Health Sciences Center, Sanford Roger Maris Cancer Center, Berkshire Medical Center, New York Weill Cornell Medicine, Mobimed Technologies, University of Chicago Medicine, Johns Hopkins Medicine, Maimonides Medical Center, Nuvance Health - Vassar Brothers, Crozer Keystone Health System, Karmanos/McLaren, Vanderbilt University, Panhandle Cancer Care Center, The University of Michigan, Piedmont Healthcare, Gamma Medical Physics LLC, Mississippi Baptist Medical Center, Astarita Associates Inc, Landauer Medical Physics, RPS Oncology, Zhejiang University, University of North Carolina School of Medicine, University of Kentucky HealthCare, Peninsula Regional Medical Center, Varian Advanced Oncology Solutions, New York Proton Center, Wake Forest University Medical Center, Rutgers Robert Wood Johnson Medical School, Tx Oncology, Lewis Hall Singletary Oncology Center (John D. Archbold Hospital), Medical Physics Services, University of New Mexico, UPMC Cancer Center, Medical Physics Solutions, LLC, ECU Health, Evercare Hospital Chattogram, Mercy Cancer Center, Sharp Grossmont Hospital, West Virginia University, Virginia Commonwealth University Medical Center, Thomas Jefferson University, Centennial Medical Physics, LLC, University of California, Davis, University of Miami, Varian, Inc., UAB Medical Center, Wellspan health, Cleveland Clinic Foundation, Procure Treatment Center, Retired FDA, Tufts Medical Center, Virginia Commonwealth University, Germantown Academy, Hartford Hospital, Cleveland Clinic Florida, Billings Clinic, Imalogix, University of Wisconsin - Madison, Dana Farber Cancer Institute, Massachusetts General Hospital, Johns Hopkins University, GenensisCare, VARIAN Siemens Healthineers, MedStar Washington Hospital, Illawarra Cancer Care Center, Duke Health, Corewell Health, Columbia University, Johns Hopkins, Baylor Scott & White Health, Ascension Saint Thomas Rutherford Hospital, Varian, a Siemens Healthineers company, Rabin Medical Center, Albany - Stratton VA, Florida Cancer Specialists at Tampa Cancer Center, Baylor St Lukes Medical Center, Baylor College of Medicine, Christiana Care Health System, West Physics, Mayo Clinic Arizona, Emory University, University of Pittsburgh Medical Center, Brigham and Women's Hospital, UCLA, CoxHealth, Starsino Medical Technologies Co Ltd, University of Utah Hospitals, Lahey Health Medical Center, Paul Scherrer Institute (PSI), Karmanos Cancer Institute, Radcom Associates, LLC, Ascension Wisconsin, The University of Alabama at Birmingham, Winter Park Cancer Center, Louisiana State University, UT Health San Antonio, Intermountain Health, Penn Medicine/Lancaster General Health, Elekta Xoft, University of KY HealthCare, Rutgers, Cancer Institute of New Jersey, Real Time Tomography LLC, Toronto Metropolitan University, UCSD, Dartmouth College, Ascension St. Thomas Rutherford hospital, City of Hope, Radiation Management Associates, Levine Cancer Institute, Atrium Health, Varian Medical Systems, Blount Memorial Hospital, Penn State University, Therapy Physics, Inc., Northwest Community Hospital, Duke University Medical Center, Advent Health, Miami Cancer Institute, Washington State Department of Health, Lantheus Medical Imaging, Chesapeake Potomac Regional Cancer Center, MRP Inc., University of Chicago, University of Tennessee Medical Center, Huntsman Cancer Institude, University of Utah, Oregon Health and Science University, Hutchinson Regional Medical Center, Winchester Medical Center, WellSpring Oncology, Medical School of East Carolina Univ, Weill Cornell Medical Center, UPMC Hillman Cancer Centers, Springfield Clinic, CaliberMRI, Inc., Prisma Health, Helen F. Graham Cancer Center, ChristianaCare, Upstate Medical Physics, PC, Loma Linda University Medical Center, Radpocket LLC, RayzeBio, St. Peter's Health Partners, MJS Medical Physics Inc., UCHealth, Astarita Associates, Image X Institute, School of Health Sciences, University of Sydney, Oregon Urology Institute, Seoul National University Hospital, GenesisCare, Reid Health, National Institutes of Health (NIH), Bayhealth Medical Center, Albany Medical College, Advocate Radiation Oncology, Rush, Krueger-Gilbert Health Physics, Sentara Healthcare, Accuray Incorporated, CTSI, RTI Group North America, University of Louisville, Thomas Jefferson University Hospital, NCI, West Physics Consulting, LLC, Boston Children’s Hospital, CHOP, Greater Baltimore Medical Center, Florida Cancer Specialist & Research Institute, Radformation, Texas Oncology South Austin Cancer Center, Mosaic Life Care Cancer Center, University of Virginia, CPDS, Ravenel Oncology Center, M Health Fairview, Torrance Memorial Medical Center, RJK Medical Physics, Inc., NYU Langone-Long Island, Trinity CancerCare Center, Bryn Mawr Hospital, Sanford Health, University of Michigan Health Systems, One Physics - Ohio Medical Physics Consulting, West Michigan Cancer Center, University Hospitals Cleveland Medical Center, Levine Cancer Institute/Atrium Health, Advanced Biophotonics Laboratory, University of Massachusetts Lowell, UConn Health, U.S. Nuclear Regulatory Commission, Wayne State University, University of Oklahoma Health Science Center, Houston Methodist Hospital, Varian, Arizona Center for Cancer Care, NIH Clinical Center, Stanford University, Hospital of the University of Pennsylvania, Peel Regional Cancer Center, Credit Valley Hospital, University of Alabama Birmingham, Lark Physics, Ackerman Cancer Center, Southern District Health Board, Milestone Medical Physics Group, UTHealth Houston McGovern Medical School, Rutgers University, West County Radiological Group, Mayo Clinic, Philips Healthcare, University of Vermont Medical Center, Novant Health at Presbyterian Medical Center, Harvard Medical School, Ratio Therapeutics, Naval Medical Center Portsmouth, University Colorado Denver, School of Medicine, Sutter Santa Cruz Radiation Oncology, Radiophysics Associates, Northside Hospital, SolutionHealth, University of Virginia Health Systems, Johns Hopkins School of Medicine, Austin Health, UPMC, St. Joseph Mercy Health System, Cancer Center of Hawaii, Centra Health, Aspekt Solutions, Winter Haven Hospital, Henry Ford Hospital System, Medical University of South Carolina, Maine Medical Center, Phoenixville Hospital, National Institutes of Health, Associated Medical Professionals, Gundersen Health System, St. Luke's University Health Network, Univesity of Victoria, Department of Radiation Oncology, Stanford University School of Medicine, Washington University in St. Louis, Queen's Medical Center, West O'ahu, Canon Medical Research USA, Inc., Robert Wood Johnson University Hospital, UVA Health System, Section for Biomedical Physics, Department of Radiation Oncology, University Hospital and Medical Faculty, Eberhard Karls University Tübingen, Centennial Medical Physics, McLaren Cancer Institute, Cancer Care Group, Texas Oncology-Tyler, CTSI Oncology Practice Solutions, a varian company, Bank of Cyprus Oncology Centre, Columbus Regional Hospital, Central Florida Cancer Insititute, Texas Oncology - San Antonio, The Ohio State University, Stony Brook University, Greenwich Hospital, INOVA Schar Cancer Institute, Marsden Medical Physics Associates, Allegheny Health Network, Geisinger Health System, University of Maryland Medical System, Texas Oncology, Mount Sinai Medical Center, TrueNorth Medical Physics, Mallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, Houston Methodist Hospital, Houston, TX, Martin Memorial Medical Center, Yale University School of Medicine, Comprehensive Cancer Centers of Nevada, ASR Institute for Cancer Care, Research & Rehabilitation, University of Louisville Brown Cancer Center, Jaeger Corporation, UC San Francisco, Inova Hospital at Fairfax, Upstate Medical Physics, Cedars-Sinai Medical Center, Brown University Health, Texas Oncology-Denton, Assarian Cancer Center, HCA Healthcare, San Diego State University, Cooper University HealthCare, LVeldkamp MedPhys Services, LLC, Morristown Medical Center, Atlantic Health System, OMPC Therapy, LLC & OMPC Diagnostic, LLC, Defense Health Agency, Radiation Oncology, Medical College of Wisconsin, UT Southwestern Medical Center, Kaiser Permanente Bellflower Medical Center, Roswell Park Comprehensive Cancer Center, University of Victoria, MD Anderson Cancer Center at Cooper, Siemens Healthineers, Monmouth Medical Center, Memorial Sloan Kettering Cancer Center, Ironwood Cancer & Research Centers, University of Cincinnati, School of Medical Sciences, Fujita Health University, University of Kentucky/UK HealthCare, University of California, San Francisco, Instituto Nacional do Cancer, Brazil, IBA Dosimetry GmbH, Westchester Medical Center, Ohio State Univ, Houston Methodist, Medical College of Wisconsin, Columbia University Medical Center, Department of Radiation Oncology, College of Medicine, University of Arkansas for Medical Sciences, UT MD Anderson Cancer Center, DFCI/BWCC south shore, Providence Cancer Center, Memorial Sloan-Kettering Cancer Center, American Association of Physicists in Medicine, Lynn Cancer Institute - Radiation Oncology, Renown Health, Purdue Univ, Beth Israel Deaconess Medical Center, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Holy Family Hospital, OhioHealth, IBA Dosimetry, Memorial Hospital Gulfport, University of Florida, George Washington Univ, University of Cincinnati Medical Center, Hubbard, Zickgraf, & Broadbent, Accuray Inc, UVRMC, MIM Software, Massachusetts General Hospital and Harvard Medical School, Mem. Sloan Kettering Cancer Ctr, UF Health Proton Therapy Institute, California Medical Physics, Inc., Henry Ford Health, UPMC Hillman Cancer Center, Vanderbilt University School of Medicine, Saddleback Memorial Medical Center, Stony Brook University Medical Center, University of Pennslyvania, TOP Physics Consulting, Nuvance/Norwalk Hospital, Oregon Health & Science Univ, Brigham & Women's Hospital, University of Pennsylvania, McLaren – Greater Lansing, American Board of Radiology, Penn Medicine | Virtua Radiation Oncology, University of Tennessee, OneOncology, University of Colorado, Indiana University Medical Center, Stronach Regional Cancer Centre, Yale New Haven Health, Vanderbilt University Medical Center, Emory Healthcare / Winship Cancer Institute, Cape Fear Valley Radiation Oncology, Northwell Health, Sutter Health, Virginia Mason Medical Center, MUSC Health- Florence Medical Center, Departement of Radiation Oncology, Curie Institute, Paris, University of Michigan, MD Anderson Cancer Center, University of Alabama at Birmingham, Radiology Inc., Cedars Sinai Hospital, Roswell Park Cancer Institute, Duke University Health System, VA Hospital, DVA Medical Ctr., JFK Medical Center, Mount Sinai West, National Cancer Institute, Chung Nam National University Sejong Hospital, Indiana Univesity, AdventHealth Daytona Beach, Orlando Health, Clinical Research Institute HUS, Northwest Medical Physics Center, University of Pennsylvania, Penn Medicine, Kettering Health Network, Children's Mercy Kansas City, IBA, UMass Memorial Hospital, US Oncology, Kaiser Permanente Southern California Medical Group, The Queen's Health System, NewYork-Presbyterian, Miami Valley Hospital, Karlsruhe Institute of Technology, Piedmont Hospital, Accuray Inc., VARIAN - Advanced Oncology Solutions, GE Healthcare, Virtua Health, Northwestern Medicine Chicago Proton Center, CARO/Montgomery Cancer Center, Walter Reed National Military Medical Center, InterMountain Health Care, Englewood Hospital and Medical Center, Henry Ford Health System, Fluke Health Solutions, Texas Oncology, PA, Inova Alexandria Hospital, New Milford Hospital, Fox Chase Cancer Center, Radiation Therapy and Cancer Inst, Penn State College of Medicine, University of California San Francisco, Unity of Oncologic Therapy S.A., Canon Medical Systems USA, Kaiser Permanente, Baptist Health Paducah, Salina Regional Health, Centre d'Oncologie de la Cote Basque, Minneapolis Radiation Oncology, Coastal Carolina Radiation Oncology, Saint Francis Hospital, Advocate Christ Medical Ctr, Universidad de Costa Rica, CAMP, Blessing Hospital, Texas Oncology Cancer Ctr, CommonSpirit Health, Navy Medical Forces Atlantic, Regions Hospital, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Methodist Hospital, Champlain Valley Physicians Hospital, Mayo Clinic Jacksonville, OHSU, Promedica Health System, Arthur JE Child Comprehensive Cancer Centre, Rhode Island Hospital / Warren Alpert Medical, UPMC Pinnacle Health, Vassar Brothers Hospital, McLeod Regional Medical Center, RJ Tokarz MIRS, St. Francis Hospital, Astarita Associates, Inc., UC Davis Medical Center, Mount Nittany Medical Center, Covenant Radiation Center, National Institute of Standards and Technology, AdventHealth Orlando, St Helena Hospital, Icon Cancer Centre, University of Washington, Indiana University, TrueNorth Medical Physics LLC, Medstar Georgetown University Hospital, Harold Alfond Center for Cancer Care, MN Oncology, Jupiter Medical Center, GE HealthCare, Rochester General Hospital, Piedmont Health, Atrium Health, Minneapolis VA Health Care System, CentraCare Health System, OMPC Diagnostic LLC, Evergreen Health Medical Center, CAMC Cancer Center - Beckley, University of Kansas Medical Center, Avera McKennan, Cleveland Clinic, Louisiana Tech University

Abstract Preview: N/A...

New Insights into Automatic Treatment Planning for Cancer Radiotherapy Using Explainable Artificial Intelligence.

Authors: Md Mainul Abrar, Yujie Chi

Affiliation: University of Texas at Arlington, Department of Physics, University of Texas at Arlington

Abstract Preview: Purpose: Healthcare 5.0, proposed in 2021, includes interpretable healthcare analysis as a core component. Achieving this requires the application of explainable artificial intelligence (XAI) to overc...

One Year Experience of Biology-Guided Radiotherapy (BgRT) on PET-Linac in an Academic Center

Authors: Shahed Badiyan, Girish Bal, Thomas I. Banks, Bin Cai, Tu Dan, Aurelie Garant, Andrew R. Godley, Steve Jiang, Orhan Oz, Arnold Pompos, Rameshwar Prasad, Chenyang Shen, David Sher, Robert Timmerman, Kenneth Westover

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical

Abstract Preview: Purpose: Biology-guided radiotherapy (BgRT) is a novel FDA-cleared technology for treating lung and bone tumors based on 18F-FDG PET uptake. This study summarizes the first-year experience treating 29...

Optimizing EBRT Workflow: Impact of Physics-Managed, Centralized Task Scheduling on Treatment Timeliness

Authors: Carl D. Elliston, Michael J. Price, Adam C. Riegel, Yi-Fang Wang

Affiliation: Columbia University Irving Medical Center

Abstract Preview: Purpose: To quantify the impact on the timely initiation of EBRT patient treatments when a workflow is implemented for which a core team of physicists (CTP) oversees the scheduling of all patient-cent...

Optimizing Motion Profiles of a Dynamic Collimator in Proton Therapy

Authors: Simona Cacciatore, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Julien Smeets, Blake R. Smith, Nhan Vu, Karsten K. Wake

Affiliation: University of Wisconsin, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care

Abstract Preview: Purpose: To evaluate time reduction strategies for the Dynamic Collimation System (DCS) using an IBA (Louvain-la-Neuve, Belgium) proton therapy system. Delivery time for a multi-energy-layer patient s...

Optimizing Prostate Cancer Radiotherapy: Comprehensive Analysis of Automated Planning with Neural Network-Based Dose Prediction

Authors: Seungtaek Choi, Laurence Edward Court, Eun Young Han, Yusung Kim, Hunter S. Mehrens, Tucker J. Netherton, Shiqin Su

Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Automated treatment planning is gaining traction for its enhanced consistency and efficiency. A key challenge, however, lies in the inability of neural network dose predictions directly trans...

Optimizing Quality Assurance CT Frequency and Setup Uncertainty in Brain Proton Therapy Patients for Reduced Normal Tissue Dose

Authors: Rachel B. Ger, Heng Li, Anh Tran

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: Proton therapy patients undergo quality assurance CT scans (QACTs) during treatment to verify dosimetric accuracy and utilize robustness scenarios for setup and range uncertainties. For intra...

Physics and Geometry Input-Based Neural Network Dose Engine

Authors: Ricardo Garcia Santiago, Narges Miri, Daryl P. Nazareth, Ankit Pant, Mukund Seshadri

Affiliation: Roswell Park Comprehensive Cancer Center

Abstract Preview: Purpose: To develop a transformer-based deep learning network framework for predicting VMAT dose distributions. This can provide fast and efficient calculations with accuracies potentially comparable ...

Plan Optimization Parameter Impact on Gamma Pass Rates

Authors: Parham Alaei, Timothy J Allen, Tomas Agustin Montenegro

Affiliation: University of Minnesota, Department of Radiation Oncology, University of Minnesota, Minneapolis

Abstract Preview: Purpose:
To assess possible relationships between treatment plan optimization parameters and gamma pass rates in quality assurance (QA) analysis of IMRT/VMAT plans.
Methods:
Plan optimization...

Post-Implant Dosimetry (PID) between 1D and 2D Cs-131 Seed Models for Post-Op Cavities in Recurrent GBM Patients

Authors: Cindy Pham, Anurag Sharma, John Starner, Ching-Ling Teng, Michael A. Trager, Gabriella Wernicke

Affiliation: Northwell, Northwell Health, Radiation Medicine, Northwell Health

Abstract Preview: Purpose: Precisely identifying orientation of implanted seeds on post-implant CTs is challenging. This research addresses the dosimetric uncertainties stemming from uncertainties in identifying seed o...

Preclinical Dosimetric Evaluation for Small Animal Study to Investigate Normal Tissue-Sparing Effects in the Electron Ultra-High Dose-Rate (FLASH) Environment

Authors: Ashok Bhandari, Andrew Joseph Fanning, Kyle J. Gallagher, Brendan Graff, Christopher Jenkins, Kyuhak Oh, Ying Yan, Su-Min Zhou

Affiliation: University of Nebraska Medical Center

Abstract Preview: Purpose: This study aimed to design a robust experimental setup to ensure accurate dose delivery using ultra-high-dose-rate for small animal experiments by conducting dosimetric evaluations prior to a...

Predicting Brain V60% in Linac-Based Single-Isocenter-Multiple-Targets (SIMT) Stereotactic Radiosurgery Using Machine Learning

Authors: John Ginn, Zhuoyun Huang, Yongbok Kim, Ke Lu, Chunhao Wang, Yibo Xie, Zhenyu Yang, Jingtong Zhao

Affiliation: Duke University, Duke Kunshan University

Abstract Preview: Purpose: This study aims to develop and validate a machine learning model for predicting V60%, a critical dosimetric metric in LINAC-based Single-Isocenter-Multiple-Targets (SIMT) stereotactic radiosu...

Proton Pencil Beam Scanning Ultra-High Dose Rate 3D Lattice Radiotherapy: A Proof-of-Concept Flash Sfrt Study

Authors: Richard Bakst, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Minglei Kang, Nancy Y Lee, Haibo Lin, Hang Qi, Charles B. Simone, Pingfang Tsai, Milo Vermeulen, Shouyi Wei, Xiaodong Wu, Lee Xu, Irini Yacoub, Xingyi Zhao, Ajay Zheng

Affiliation: University of Miami, Peking University, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, icahn school of medicine at mount sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose:
Three-dimensional lattice radiation therapy (3D-LRT) effectively achieves local tumor control with limited morbidity. Pencil beam scanning (PBS) proton therapy provides precise dose confor...

Quantitative Analysis of Dose Perturbation from Gantry Rotational Errors in Dynamic Spot-Scanning Proton Arc Therapy (SPArc)

Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Lewei Zhao

Affiliation: Department of Radiation Oncology, Stanford University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital

Abstract Preview: Purpose:
This study investigates the dosimetric impact of systematic and random gantry position errors (GPE) during dynamic Spot-Scanning Proton Arc Therapy (SPArc) delivery.
Methods:
Four ca...

Quantitative Fluorescence Molecular Tomography Guide Radiation Therapy

Authors: Jiahao Chen, Yunwen Huang, Yidong Yang, Shanshan Zhang, Ning Zhao, Cheng Zheng

Affiliation: Department of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China

Abstract Preview: Purpose: To develop a molecular image-guided radiotherapy technique for accurate and effective radiation treatment using quantitative fluorescence molecular tomography (FMT).
Methods: X-ray cone be...

Radiation Oncology Case Rate Model

Authors: Anne Hubbard

Affiliation: ASTRO

Abstract Preview: N/A...

Radiation Sub-Segmentectomy in 90y Radioembolization: Post-Therapy Dosimetry, Treatment Response, and Pathological Necrosis

Authors: Guilherme Rosa Ferreira, Dan Giardina, John Karageorgiou, Chris Malone, Allan Thomas

Affiliation: Washington University School of Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine

Abstract Preview: Purpose: Radiation segmentectomy has become a primary strategy in 90Y radioembolization, with localized treated volumes that can include up to two liver segments. The goal is complete pathological nec...

Radiochemical Monte Carlo Model to Investigate the Oxygen Impacts on Radical Yields Under Proton Flash Irradiation

Authors: Yao Hao, Yuting Peng, Francisco Javier Reynoso, Tianyu Zhao, Xiandong Zhao

Affiliation: Varian, University of South Florida, Washington University School of Medicine, Washington University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose: Ultra-high dose-rate (FLASH) dose rate (> 40 Gy/s) may result in a radio-protective effect in healthy tissue compared with conventional dose rate (CDR). This effect has been observed in vivo ...

Ratoguide: Evaluation of AI-Driven Fully Automated Treatment Planning Support System for Lung SBRT

Authors: Keiichi Jingu, Noriyuki Kadoya, Takafumi Komiyama, Takeru Nakajima, Hikaru Nemoto, Hiroshi Onishi, Masahide Saito, Ryota Tozuka

Affiliation: Department of Radiology, University of Yamanashi, Department of Radiation Oncology, Tohoku University Graduate School of Medicine, Department of Advanced Biomedical Imaging, University of Yamanashi

Abstract Preview: Purpose: We evaluated the accuracy of a new AI-based fully automated planning software in stereotactic body radiotherapy (SBRT) for early-stage lung cancer.
Methods: We collected data from 125 pati...

Real-Time 3D Dose Verification for MR-Guided Online Adaptive Radiotherapy (ART) Via Geometry-Encoded Deep Learning Framework

Authors: Steve B. Jiang, Dan Nguyen, Chenyang Shen, Fan-Chi F. Su, Jiacheng Xie, Shunyu Yan, Daniel Yang, Ying Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Fast dose verification is essential for the safety and efficiency of MR-guided adaptive radiotherapy (ART) as patients anxiously waiting on the treatment couch. Conventional tools often requi...

Real-Time Proton and Carbon Ion Monte Carlo Dose Calculation through GPU-Acceleration and DL-Based Denoising Algorithms

Authors: Yankui Chang, Shijun Li, Xi Pei, Ripeng Wang, Xuanhe Wang, X. George Xu, Qing Zhang, Jingfang Zhao

Affiliation: University of Science and Technology of China, Shanghai proton and heavy ion center, School of Nuclear Science and Technology, University of Science and Technology of China, Anhui Wisdom Technology Co., Ltd.

Abstract Preview: Purpose:
This paper describes disruptive methods using both GPU-based MC simulation and deep-learning (DL)-based MC denoising algorithms, as well as clinical tests involving more than 560 patient p...

Recovery Factor Comparisons for Reirradiation Overlapping the Spinal Cord

Authors: Xinxin Deng, Issam M. El Naqa, Jimm Grimm, Lijun Ma, Vitali Moiseenko, Timothy E. Schultheiss, Gopal Subedi, Wolfgang A. TomĂŠ, Ellen D. Yorke, Albert van der Kogel

Affiliation: Montefiore Medical Center, Wellstar Kennestone Hospital Cancer Center, H. Lee Moffitt Cancer Center, Department of Human Oncology, University of Wisconsin–Madison, Department of Radiation Oncology, Wellstar Health System, Radiation Oncology, Keck School of Medicine of USC, Georgia Institute of Technology, University of California San Diego, City Of Hope National Medical Centre, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Reirradiation is increasingly utilized in clinical practice but dose-time recovery factors for human subjects remain uncertain. We constructed a reirradiation recovery model for spinal cord e...

Rectal Spacer Injection on the Day of HDR Prostate Brachytherapy Enhances Dosimetry and Reduces Rectal Dose for Patients Receiving Combined Brachytherapy and EBRT.

Authors: Francis A Asamoah, David D. Campos, Jordan A Holmes, Ke Colin Huang, Omar Ishaq, Sook Kien Ng, Arpan Prabhu, Edwin Quashie, Yong Yue

Affiliation: Indiana University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose: Evaluate a novel rectal spacer workflow with spacer injection during brachytherapy to streamline logistics, reduce hospital visits and costs, and compare the benefits of SpaceOAR Vue and Barr...

Refined Nnu-Net Training for Practice-Specific Autosegmentation of APBI Targets

Authors: Daniel A. Alexander, Jonathan Baron, Brook Kennedy Byrd, William Ross Green, Bolin Li, Rafe A. McBeth, Abigail Pepin, Steven Philbrook

Affiliation: Department of Radiation Oncology and Applied Sciences, Department of Radiation Oncology, University of Pennsylvania, Thayer School of Engineering, University of Pennsylvania

Abstract Preview: Purpose: As accelerated partial breast irradiation (APBI) gains traction, the prospect of a rapid sim-to-completion of treatment workflow is an attractive option for patients. While OAR autocontouring...

Reinforcement Learning Based Machine Parameter Optimization for Two-Arc Prostate VMAT Planning

Authors: William T. Hrinivich, Junghoon Lee, Lina Mekki

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University, Johns Hopkins University

Abstract Preview: Purpose: Volumetric modulated arc therapy (VMAT) planning is a computationally expensive process. In this work, we propose a reinforcement learning (RL) framework to automatically optimize dose rate a...

Reliable Markerless Lung Tumor Tracking with Built-in Patient-Specific Quality Assurance

Authors: Weixing Cai, Laura I. Cervino, Qiyong Fan, Yabo Fu, Tianfang Li, Xiang Li, Jean M. Moran, Hai Pham, Pengpeng Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: AAPM Task Group Report 273 emphasizes the importance of rigorous validation to ensure the generalizability and robustness of machine learning-based clinical tools before their implementation ...

Retrospective Analysis of Treatment Pauses Due to Intrafraction Movement for Frameless Single Fraction Gamma Knife Icon Radiosurgery

Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang

Affiliation: FCCC at Temple University Hospital

Abstract Preview: Purpose: Frameless gamma knife (GK) treatments use a thermoplastic mask coupled with high-definition motion management system that utilizes an infrared camera, and a reflective marker placed on the pa...

Retrospective Evaluation of Combined Photon SBRT and Radium-223 SPECT Based Radiopharmaceutical Therapy Tumor Dosimetry in Clinical Trial Patient Cases

Authors: David P. Adam, Allison Cartee, Eric C. Frey, Michael Ghaly, Bin He, Robert Francois Hobbs, Natalie Rose Kania, Ana Kiess, Ian Marsh, Bonnie N. C. President, Steven Rowe, George Sgouros, Phuoc Tran, Hao Wang

Affiliation: Johns Hopkins University, Radiopharmaceutical Imaging and Dosimetry, LLC (Rapid), 2The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins Medical Institute, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Oncology, Johns Hopkins University, School of Medicine, Department of Radiology, University of North Carolina, Chapel Hill

Abstract Preview: Purpose: Advanced treatment paradigms combining SPECT/CT imageable, alpha emitting, radiopharmaceutical therapy (RPT) and stereotactic body radiotherapy (SBRT) can provide the potential of dose escala...

Retrospective Postimplant Dosimetry: Comparison of Line and Point Source for 131cs Low Dose Rate Intracranial Implant Brachytherapy

Authors: Tirthraj Adhikari, Timothy J Allen, Abdullah A. Alshreef, Clara Ferreira

Affiliation: Medical School Department of Radiation Oncology University of Minnesota, University of Minnesota, Loma Linda University Medical Center

Abstract Preview: Purpose: GammaTile Brachytherapy with 131Cs is an effective treatment for glioblastomas, offering local control with minimal radiation necrosis. While the line source model is preferred for dose distr...

Role of Medical Physicists in CT Contrast Optimization: A Case Study

Authors: Zahra Alyani Nezhad, Carrie Bartels, Rachel Bladorn, Sean D. Rose, Kelsey Schluter, Timothy P. Szczykutowicz

Affiliation: Departments of Radiology and Medical Physics, University Wisconsin-Madison, University of Wisconsin Madison, University of Wisconsin-Madison, University of Texas at Houston Medical School, University of Wisonsin-Madison

Abstract Preview: Purpose: This study presents a scientifically quantified case study that underscores the importance of the medical physicist’s contribution to contrast enhancement optimization.
Methods: CT pulmona...

Scissor-Beam Based Carbon Ion Minibeam Treatment Planning Method

Authors: Hao Gao, Qiang Li, Yuting Lin, Wei Wang, Wei Wu, Weijie Zhang

Affiliation: Institute of Modern Physics, Chinese Academy of Sciences, China, Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: Carbon minibeam radiation therapy (cMBRT) offers high peak-to-valley dose ratio (PVDR) and relative biological effectiveness. A key challenge is balancing uniform target coverage with PVDR pr...

Scoring Functions for Reinforcement Learning in Accelerated Partial Breast Irradiation Treatment Planning

Authors: Rafe A. McBeth, Kuancheng Wang, Ledi Wang

Affiliation: Department of Radiation Oncology, University of Pennsylvania, Georgia Institute of Technology, University of Pennsylvania

Abstract Preview: Purpose:
The integration of AI in clinical workflows presents unprecedented opportunities to enhance treatment quality in radiation oncology, yet it also demands innovative approaches to address th...

Simplified Method of Assessing Lung Volume Limits during the Planning Process in the Re-Treatment Environment

Authors: Sameera Kumar, Chang Ming Charlie Ma, Robert A. Price

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose:
Difficulty assessing lung limits during treatment planning in the retreatment environment can be compounded as limits are volume-based (ie. VxGy<37%) and require a critical volume with a m...

Spot Scanning Gantry-Based Gaze-Gated Ocular Proton Treatment Planning at Mayo Clinic Rochester

Authors: Amanda J. Deisher, Susannah V. Hickling, Shima Ito, Jon J. Kruse

Affiliation: CancerCare Manitoba, Mayo Clinic

Abstract Preview: Purpose:
To date, 11 ocular patients were treated with spot scanning gantry-based gaze-gated ocular proton program at Mayo Clinic, Rochester MN since 2023. Treatments are done in the half-arc gantr...

Standardizing Hybrid Angio-CT Procedure Terminology: Mapping to Acr Common Lexicon for Future Drl Establishmen

Authors: Manuel M. Arreola, Hugh Davis, Daniella Fabri, Emily L. Marshall, BC Schwarz

Affiliation: University of Florida

Abstract Preview: Purpose:
This study aims to map procedure names, descriptions, and CPT codes from a Hybrid Angio-CT room to the American College of Radiology (ACR) Common Lexicon. This mapping will support expedit...

Temporal Drift in Ir-192 Source Strength Measurements: A Braphyqs Multi-Center Analysis

Authors: Åsa K. Carlsson Tedgren, Taran Hellebust, Antonio Herreros, Jacob Johansen, Christian Kirisits, Panagiotis Papagiannis, Mark J. Rivard, Frank-Andre Siebert, Frank Verhaegen, Javier Vijande, Jan Wiersma, Marisol de Brabandere, Ruud van Leeuwen

Affiliation: UKSH, Campus Kiel, Klinik für Strahlentherapie (Radioonkologie), Department of Oncology, The Norwegian Radium Hospital, Oslo University Hospital, Radiation Physics, Department of Medicine and Health (IMH), Linköping University, Radiation Oncology Department, Hospital Clínic-Universitat de Barcelona, IDIBAPS, IFIC-UV, Radiation Oncology, Amsterdam UMC location University of Amsterdam, Department of Radiation Oncology, Radboud University Medical Center, Department of Oncology, Aarhus University Hospital, University Hospital Gasthuisberg, Dept. of Radiation Oncology, Medical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Department of Radiation Oncology (MAASTRO), GROW – School for Oncology and Reproduction, Maastricht University Medical Centre+, Department of Radiation Oncology, Comprehensive Cancer Center, Medical University of Vienna, Warren Alpert Medical School of Brown University

Abstract Preview: Purpose: This study, which was carried out by the GEC-ESTRO BRAPHYQS working group, reports the increasing divergence between clinical reference air kerma rate (RAKR) measurements and vendor-provided ...

The Feasibility of Ethos-Based Pulsed Reduced Dose-Rate (PRDR) Radiotherapy

Authors: Chia-Lung Chien, Renteng Hou, Wen C. Hsi, Faraz Kalantari, Ganesh Narayanasamy, Zhong Su

Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)

Abstract Preview: Purpose:
PRDR is an effective re-irradiation treatment for patients who have already reached the tolerance dose to their organs at risk (OARs). While PRDR is implemented on TrueBeam by limiting the...

The GYN Webapp: A Centralized Tool for Enhancing HDR Brachytherapy Treatment Quality and Clinical Outcomes

Authors: Kevin Albuquerque, Ti Bai, Yesenia Gonzalez, Brian A. Hrycushko, Zohaib Iqbal, Paul M. Medin, Shanshan Tang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Cervical cancer remains one of the most common and significant gynecological (GYN) malignancies globally, often presenting at advanced stages where radiation therapy and high-dose-rate (HDR) ...

Towards Clinical Translation: Optical Methods Deliver in-Vivo per-Pulse Dosimetry in Electron Flash-RT

Authors: Petr Bruza, Rafael Carballeira, Megan Clark, David J. Gladstone, Austin Sloop, Roman Vasyltsiv, Kevin Jacob Willy

Affiliation: Dartmouth College, Thayer School of Engineering, Dartmouth College

Abstract Preview: Purpose: Develop an optical dosimetry system to accomplish standard of care on-patient dosimetry and pretreatment quality assurance for ultra-high dose rate (UHDR) electron therapy ahead of human tria...

Treatment Dose Reconstruction of Digitized Deliveries on Reflexion X1 System Based on Megavoltage Imager and Dose Monitor Chamber

Authors: Angela J Da Silva, Andrew Groll, Gopinath Kuduvalli, Thomas Laurence, David W. Meer, Manoj Narayanan, Mingshan Sun, Don Vernekohl, Ray Yang

Affiliation: RefleXion Medical

Abstract Preview: Purpose: To implement post-treatment review of delivered dose fractions on RefleXion X1 accounting for independent detection of transmitted beamlets and transient dose fluctuations of individual pulse...

Treatment Planning System Modelling of a New Commercial Rotational Table

Authors: Michael Armstrong, Courtney R. Buckey, Quan Chen, Suzanne J. Chungbin, Mirek Fatyga, Yi Rong, Jun Tan, Xiang Sheng Yan

Affiliation: Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose: To model a commercial rotational table in treatment planning system (TPS) for accurate dose optimization and calculation.

Methods: A commercial rotational table (CDR EquilibriumÂŽ) is r...

Unidose: A Universal Framework for IMRT Dose Prediction

Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Zi Yang, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Dose prediction (DP) is essential in guiding radiotherapy planning. However, current DP models for intensity-modulated radiation therapy (IMRT) primarily rely on fixed-beam orientations and a...

Universal MR-to-Synthetic CT: A Streamlined Framework for MR-Only Radiotherapy Planning

Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose:
Converting MR images to synthetic CT (MR2sCT) is highly desirable as it streamlines the radiotherapy treatment planning workflow. This approach leverages the superior soft tissue visibilit...

Unlocking Adaptive Radiotherapy Flexibility: Integrating Ethos Adaptive Therapy and Halcyon IGRT with Scripting Innovations

Authors: Min Geon Choi, Sean J. Domal, Ruiqi Li, Taoran Li, Mu-Han Lin, Yang Kyun Park, David D.M. Parsons, Justin D. Visak

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, University of Pennsylvania, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Ethos X-ray-guided online adaptive radiotherapy (ART) enables precise, daily adaptive treatments but requires significant resources, limiting widespread adoption. Many treatment sites do not ...

Use of Gold Nanoparticles As Shielding during Eye Plaque Brachytherapy

Authors: Clara Ferreira, Tomas Agustin Montenegro, Courtney C. Oare

Affiliation: University of Minnesota

Abstract Preview: Purpose: This work provides a simulated proof of concept for the use of intravitreal gold nanoparticle (AuNP) during eye plaque brachytherapy as a radiation shield to critical structures in the eye us...

Using Multiple Sequences MRI for Synthesizing CT Based on a Deep Learning Approach

Authors: Jie Hu, Nan Li, Chuanbin Xie, Shouping Xu, Xinlei Xu, Gaolong Zhang, Zhilei Zhang

Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, the First Medical Center of the People's Liberation Army General Hospital, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, PeopleĘźs Republic of China, Department of Radiation Oncology, School of Physics, Beihang University, Beijing, 102206, PeopleĘźs Republic of China

Abstract Preview: Purpose: This study aims to synthesize CT images for MRI-only radiation therapy using a deep learning approach that integrates information from the T1- and T2-weighted MRI sequence.
Methods: 97 hea...

Using Single-Energy Bragg Peak (SEBP) Flash Combined with Intensity-Modulated Proton Therapy (IMPT) for Flash Treatment in a Clinical Synchrotron-Based Proton System

Authors: Chingyun Cheng, Ben Durkee, Carri K. Glide-Hurst, Minglei Kang, Haibo Lin, Bhudatt R. Paliwal, Charles B. Simone, Zhizhen Wei, Tengda Zhang, Xingyi Zhao

Affiliation: University of Wisconsin, Department of Mechanical Engineering, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Transmission Beam (TB), Single-Energy Bragg Peak (SEBP), and Single-Energy Spread-Out Bragg Peak (SESOBP) are primary proton conformal FLASH techniques. However, each comes with significant l...

Using a-Si 1200 Epid Portal Dosimetry for VMAT Commissioning

Authors: Ryan Burri, Nazanin Hoshyar, Jerry W. McCoy, Yulin Song, Huma Syed

Affiliation: Bay Pines VA Medical Center

Abstract Preview: Purpose: The study aimed to streamline traditionally manual, iterative, and time-consuming VMAT commissioning process. The goal was to identify an optimal set of MLC dosimetric parameters that minimiz...

Validating a Pre-Existing CT HU-to-Mass Density Curve for Direct Dose Calculation on High Quality Cbcts

Authors: Casey E. Bojechko, Tricia Chinnery, Grace Gwe-Ya Kim, Xenia Ray

Affiliation: University of California San Diego

Abstract Preview: Purpose: To evaluate the use of a calibration curve generated from the CT simulator for direct dose calculation on cone beam computed tomography (CBCT) images taken with the on-board imaging system. T...

Weakly Supervised Spatial Implicit Neural Representation Learning for 3D MRI-Ultrasound Deformable Image Registration in HDR Prostate Brachytherapy

Authors: Michael Baine, Yang Lei, Yu Lei, Ruirui Liu, Tian Liu, Jing Wang

Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center

Abstract Preview: Purpose: Accurate 3D deformable registration of MRI and ultrasound (US) is essential for real-time image guidance during high-dose-rate (HDR) prostate brachytherapy. However, MRI-US registration of th...

What Do We Do with Our Old Pinnacle Data?

Authors: Caiden Atienza, Daniel E. Hyer, Samuel D. Rusu, Blake R. Smith, Joel J. St-Aubin

Affiliation: Iowa Health Care, University of Iowa

Abstract Preview: Purpose: Pinnacle3 TPS (Philips Radiation Oncology Systems, Fitchburg, WI, USA) support is set to end by December 31, 2026. This work presents a validated method to archive Pinnacle data, which may be...

“You Can’t Unsee It”: Clinical Scintillation Imaging Enables First Localized Comparison between In Vivo dosimetry Measurements and the Treatment Plan

Authors: Petr Bruza, Megan Clark, David J. Gladstone, Lesley A Jarvis, Allison Matous

Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health

Abstract Preview: Purpose: In vivo dosimetry (IVD) is underutilized, in part, because measured point doses cannot be accurately localized to the patient or treatment planning system (TPS), complicating the clinical and...