Authors: Rohith Kaiyum, Ozzy Mermut, Alexandra Rink
Affiliation: Department of Medical Biophysics, University of Toronto, Department of Physics and Astronomy, York University
Abstract Preview: Purpose: To investigate the relationship between chemical features and real-time response to ionizing radiation dose of radiochromic diacetylene crystals.
Methods: A number of radiochromic diacetyl...
Authors: Xu Cao, Wesley S. Culberson, Aubrey Parks, Brian W Pogue, William Scott Thomas
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison
Abstract Preview: Purpose:
The hydrated electron is a critical reactive species generated during the radiolysis of water when ionizing radiation interacts with biological tissues. It plays a pivotal role in mediatin...
Authors: Xun Jia, Youfang Lai
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Ultrahigh dose rate FLASH (>40 Gy/s) radiotherapy (RT) has attracted significant attention. The mechanism remains unclear, hindering clinical translation. This study investigated the behavior...
Authors: Ramin Abolfath, Alexander Baikalov, Stefan Bartzsch, Nolan M. Esplen, Alan Eduardo Lopez Hernandez, Emil Schueler
Affiliation: MD Anderson Cancer Center, PI Experimental Medical Physics, Institute of Radiation Medicine (IRM), Helmholtz Munich, Germany, Howard University, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: FLASH radiation therapy (FLASH-RT) leverages ultra-high dose rates (UHDR) to spare normal tissue as compared to conventional (CONV)-RT while preserving tumor control; this is termed the FLASH...
Authors: Alejandro Bertolet, Jorge Naoki Dominguez Kondo, Bruce A. Faddegon, Kathryn D Held, Nicolas Henthorn, Jay LaVerne, Thongchai Masilela, Stephen J. McMahon, Isaac Meyer, Victor V. Onecha, Harald Paganetti, Jose A. Ramos-Mendez, Jan PO Schuemann, Wook-Geun Shin, Michael Taylor, John Warmenhoven
Affiliation: Massachusetts General Hospital, Queen's University Belfast, Massachusetts General Hospital and Harvard Medical School, University of California San Francisco, University of Manchester, Notre Dame University
Abstract Preview: Purpose: TOPAS-nBio brings a cutting-edge Monte Carlo (MC) simulation framework to the research community to test hypotheses of radiation effects at the nanometer/cell scale. Here, we present the deve...