Search Submissions 🔎

Results for "cine acquired": 51 found

12 Year Clinical Experience with Low-Tesla MRI for Tumor Progression

Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens

Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI

Abstract Preview: Purpose:
Low-Tesla MRI (0.23T Panorama MR Scanner, Philips) has been used for tumor progression during proton therapy treatments, and for initial contouring in addition to diagnostic MRI. The pulse...

4D CBCT Reconstruction Using Denoising Diffusion Implicit Models

Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Bohong Huang, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Four-dimensional cone-beam computed tomography (4D-CBCT) is critical in image-guided radiotherapy (IGRT) for visualizing tumor motion. However, sparse projection sampling often introduces sev...

A Deformable Registration-Based Pipeline for the Characterisation of Respiratory Motion from 2D Lung Cine MRI

Authors: Michael W. Kissick, Chung Tin Lo, Jamie R McClelland, Niek Schreuder, Tracy Underwood

Affiliation: Hawkes Institute, University College London, Leo Cancer Care

Abstract Preview: Purpose: The emerging field of upright radiotherapy raises the question of how respiratory motion differs between upright and supine treatment postures. Therefore, we have developed a versatile pipeli...

A Hybrid Transformer-CNN for Tracking-Free 3D Ultrasound Volume Reconstruction from 2D Freehand Scans

Authors: Wenfeng He, Tian Liu, Pretesh Patel, Richard L.J. Qiu, Keyur Shah, Tonghe Wang, Xiaofeng Yang, Chulong Zhang

Affiliation: Icahn School of Medicine at Mount Sinai, Emory University, Medical Physics Graduate Program, Duke Kunshan University, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: This study introduces a tracking-free approach to reconstruct 3D ultrasound (US) volumes from 2D freehand US scans. By eliminating the reliance on external tracking systems, this method aims ...

A Pilot Study to Implement a Definitive Breast SBRT Technique

Authors: Charmainne Cruje, Maria Dumol, Nawroz Fatima, Marisa Finlay, Kalaina Johnson, Raman Mohla, Jasleen Uppal

Affiliation: Trillium Health Partners, Carlo Fidani Regional Cancer Centre

Abstract Preview: Purpose: To evaluate the robustness of a breast SBRT protocol in achieving target coverage by utilizing online- and retrospectively-matched CBCT-to-CT images.
Methods: The first pilot patient was s...

A Qualitative Evaluation of the Prostate Patients Hscbct Images and Limbus Contours

Authors: Doris Dimitriadis/Dimitriadou, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Adam Olson

Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, UPMC

Abstract Preview: Purpose: The objective of this study was to qualitatively evaluate Prostate Hypersight Cone-Beam CT (HSCBCT) images and assess its capability for Limbus auto-contouring. The qualitative evaluation and...

Advanced Daily Imaging Technology Improves Tracking of Soft Tissue Decomposition for Head and Neck Cancer Patients Receiving Radiotherapy

Authors: Robert K Chin, Klea Hoxha, Erika Jank, Jesus Juarez, Eulanca Yuka Liu, Dylan P. O'Connell, X. Sharon Qi, Ricky R Savjani

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, Los Angeles, UCLA Radiation Oncology

Abstract Preview: Purpose:
Daily cone beam CT (CBCT) images are acquired prior to each radiotherapy treatment for verifying patient positioning. HyperSight is an advanced imaging solution that replaces standard CBCT...

An Assessment of the Potential Impact of the Elekta Unity’s 1.5T Magnetic Field upon the Performance of a Conventional Linac Installed in an Adjacent Vault: A Case Study

Authors: Matthew Stephen Andriotty, Taoran Cui, Josh Kilian-Meneghin, Ke Nie, Xiao Wang, Zhenyu Xiong, Ning J. Yue, Yin Zhang

Affiliation: Rutgers Cancer Institute of New Jersey, RWJBarnabas Health

Abstract Preview: Purpose: To investigate the potential impact of the Elekta Unity’s 1.5T magnetic field upon the performance of a conventional linac installed in an adjacent vault.
Methods: The linac vaults for thi...

Application of a Conditional Diffusion Model to Improve Real-Time MR Imaging in Online Adaptive MR-Guided Radiotherapy

Authors: Hideaki Hirashima, Haruo Inokuchi, Nobutaka Mukumoto, Naruki Murahashi, Mitsuhiro Nakamura, Megumi Nakao, Keiko Shibuya, Linna Zhang

Affiliation: Kyoto University, Osaka Metropolitan University

Abstract Preview: Purpose:
To transform the quality of 2D cine MR images acquired during online adaptive MR-guided radiotherapy (OA-MRgRT) by utilizing a conditional diffusion model to achieve image quality comparab...

Assessing Breast Cancer Tumor Segmentability on an Investigational, Double-Bolus, Prone-to-Supine Breast MRI Protocol for Surgical Guidance.

Authors: Richard J Barth, Brook Kennedy Byrd, Roberta DiFlorio-Alexander, Misty J Fox, Venkat Krishnaswamy, Keith D. Paulsen, Timothy B Rooney

Affiliation: Cairn Surgical Inc., Dartmouth Health, Thayer School of Engineering, Dartmouth Hitchcock Medical Center, University of Virginia Health, CairnSurgical Inc.

Abstract Preview: Purpose: Supine breast MRI enables precise surgical planning with demonstrated benefit in decreasing positive margin rates during BCS. However, acquiring supine breast MRI scans in a secondary imaging...

Clinical Application of Biology-Guided Radiotherapy (BgRT) to Patient Having a Cardiac Implantable Electronic Device (CIED)

Authors: Girish Bal, Thomas I. Banks, Bin Cai, Yesenia Gonzalez, Zohaib Iqbal, Paul M. Medin, Rameshwar Prasad, Chenyang Shen, Robert Timmerman, Yuanyuan Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical

Abstract Preview: Purpose: Each year more than one million pacemakers and 200k cardioverter-defibrillators are implanted in patients worldwide. The presence of a CIED introduces challenges to the delivery of radiation ...

Commissioning Silicone Tissue-Compensating Bolus for Electron Beam Therapy

Authors: Carla D. Bradford, Linda Ding, Yansong Geng, Alan Hartford, I-Lin Kuo, Salvatore LaRosa, Joshua N Wancura

Affiliation: University of Massachusetts Chan Medical School

Abstract Preview: Purpose: When treating nasal skin cancers, electron beam radiotherapy dose distributions can be improved by using custom bolus to compensate for uneven surfaces. Here we describe our experience commis...

Comparative Analysis of Nine Deep Learning Architectures for Variable Density Grappa 1H Magnetic Resonance Spectroscopy Imaging (MRSI) Reconstruction

Authors: Kimberly Chan, Anke Henning, Mahrshi Jani, Andrew Wright, Xinyu Zhang

Affiliation: Advanced Imaging Research Center (AIRC), UT Southwestern Medical Center

Abstract Preview: Purpose: To evaluate the performance of multiple deep learning architectures for MRSI reconstruction and determine their effectiveness in maintaining high-resolution metabolite mapping while reducing ...

Comparison of Frame-Based and Frameless Gamma Knife Coordinate Spaces for Treatment of Trigeminal Neuralgia

Authors: Tatiana Bejarano, Omer Gal, Alonso N. Gutierrez, Matthew D. Hall, Rupesh Kotecha, Yongsook C. Lee, Michael W. McDermott, Minesh P. Mehta, Robert H. Press, Carlos M. Rivera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek

Affiliation: Miami Cancer Institute, Baptist Health South Florida

Abstract Preview: Purpose:
Gamma Knife (GK) cone beam computed tomography-based stereotactic reference (CBCTRef) combined with pre-planning MRI, provides a flexible alternative to the historical frame-based localiza...

Comprehensive Commissioning of an O-Ring-Shaped Image-Guided Radiotherapy System with a Gimbal-Mounted Linear Accelerator

Authors: Tetsuo Fukuda, Hideaki Hirashima, Kohei Kawata, Yukako Kishigami, Takashi Mizowaki, Mitsuhiro Nakamura, Yohei Sawada, Maika Urago

Affiliation: Kyoto University, kyotoUnivercity, Hitachi high-tech, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University

Abstract Preview: Purpose: To present the comprehensive commissioning results of the O-ring shaped linac, OXRAY.
Materials and Methods: OXRAY enables a novel three-dimensional unicursal noncoplanar irradiation metho...

Data-Driven Gating in Ga-68 PET/CT: Impacts on Patient Selection and Dosimetry Predictions in Radiopharmaceutical Therapy

Authors: Zhuo Chen, Tinsu Pan, Allan Thomas

Affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine, WashU Medicine, UT MD Anderson Cancer Center

Abstract Preview: Purpose: Misregistration between data-driven gated (DDG)-PET and CT can limit the benefits of motion correction and improved localization and quantitation. DDG-CT offers a solution to these issues. He...

Deep Autoencoder for Ring Artifact Denoising in Photon-Counting CT

Authors: Magdalena Bazalova-Carter, James Day, Xinchen Deng

Affiliation: University of Victoria

Abstract Preview: Purpose:
Ring artifacts in Photon-Counting Computed Tomography (PCCT) images can degrade image quality. this study aims to suppress ring artifacts with a novel autoencoder-based framework that leve...

Deep Learning-Based Segmentation Using Cine Epid Images for Real-Time Tumor Monitoring

Authors: Fumiaki Komatsu, Shunsuke Moriya, Ryosuke Nakamura, Takeji Sakae, Toshiyuki Terunuma, Tetsuya Tomita

Affiliation: Graduate School of Comprehensive Human Sciences, University of Tsukuba, Institute of Medicine, University of Tsukuba, Proton Medical Research Center, University of Tsukuba, Department of Radiology, University of Tsukuba Hospital

Abstract Preview: Purpose: To develop a deep learning (DL) model capable of accurately tracking lung tumors independent of beam angle variations.
Methods: A thoracic dynamic phantom simulating lung motion in the sup...

Determining the Effect of Motion during Gamma Knife Stereotactic Radiosurgery on Anterior and Posterior Lesions Using an Anthropomorphic Phantom

Authors: Guang-Pei Chen, Nitish Chopra, Juan A. Garcia-Alvarez, Mi Huang, Slade J. Klawikowski, Haidy G. Nasief, George A. Noid, Abdul Parchur, Eric S. Paulson, Christina M. Sarosiek, Christopher Schultz

Affiliation: Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: During routine delivery of mask-based Gamma Knife (GK) SRS, motion is tracked via the position of a reflective sticker placed on the patient’s nose relative to two stationary reflectors on th...

Development of a Template-Based Planning Workflow for Offline Adaptive Head and Neck Cancer Using Ethos 2.0

Authors: Kaelyn Becker, Xenia Ray

Affiliation: University of California, San Diego, University of California San Diego

Abstract Preview: Purpose: Ethos 2.0 with HyperSight (Varian Medical Systems) imaging enables nearly fully automated offline adaptive radiotherapy including automated deformation of targets and recalculation on the Hou...

Dual-Modality Protoacoustic and Ultrasound Imaging for Real-Time Monitoring of Proton Therapy In Vivo

Authors: Kristina Bjegovic, Yong Chen, Lucia Rodriguez Gonzalez, Marti Roper, Liangzhong Xiang

Affiliation: University of California, Irvine, University of California Irvine, University of Oklahoma Health Sciences Center, University of Oklahoma Health Science Center

Abstract Preview: Purpose: Proton therapy is an increasingly popular cancer treatment due to its precision, enabled by the Bragg Peak (BP), which minimizes side effects. This profile necessitates in-patient localizatio...

Enhance Four-Dimension Cone-Beam Computed Tomography (4D-CBCT) from Sparse Views Using a Novel Deep Learning Model

Authors: Lei Ren, Jie Zhang

Affiliation: University of Maryland School of Medicine

Abstract Preview: Purpose: 4D-CBCT is valuable for imaging anatomy affected by respiratory motions to guide radiotherapy delivery. However, 4D-CBCT often has undersampled projections acquired in each respiratory phase ...

Enhancing Radiation Oncology Imaging with a Novel Variational Model Decomposition, Radon Transformation, and Kohonen Self-Organizing Map Denoising Framework

Authors: Hassan Bagher-Ebadian, Justine M. Cunningham, Anthony J. Doemer, Mohammad M. Ghassemi, Joshua P. Kim, Benjamin Movsas, Kundan S Thind

Affiliation: Michigan State University, Henry Ford Health

Abstract Preview: Purpose: Reduction of noise in medical images critically enables improved accuracy in delineating tumors and organs at risk, leading to more precise treatment planning and safer image-guided radiation...

Evaluation of Daily Respiratory Pattern from a Single Free-Breathing Cone Beam CT Scan

Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Xiuxiu He, Tianfang Li, Xiang Li, Hao Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose:
This work aims to develop an innovative technique to evaluate patients’ daily respiratory pattern using three-dimensional (3D) deformation vector fields (DVF) derived from a free-breathing...

Evaluation of a Commercial Metal Artifact Reduction Algorithm for IGRT in Patients with Hip Prostheses

Authors: Laura Bennett, Matthew Charles, Greg Cooley, John M. Floberg, Ryan Hutten, Elissa Khoudary, Nicholas Lynch, Kaili Ranta, Jordan M. Slagowski, Trevor Wilson

Affiliation: University of Pennsylvania, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, University of Wisconsin-Madison, University of Wisconsin-Madison

Abstract Preview: Purpose: To evaluate the impact of an iterative cone beam CT with metal artifact reduction (iCBCT+MAR) reconstruction algorithm (HyperSight TrueBeam 4.1, Varian Medical Systems) on image quality and s...

Evaluation of a Commercially Available Solution for Dose Verification Using Daily AI Generated Pseudo-CT from CBCT.

Authors: Chloe DiTusa, Panayiotis Mavroidis, Christopher W. Schneider, Sotirios Stathakis

Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center, University of North Carolina

Abstract Preview: Purpose: To evaluate and compare dose calculation differences between Monaco and AdaptBox by TheraPanacea on AI-generated pseudo-CTs (pCTs) from a CBCT.

Methods: Dose calculations in water phan...

Feasibility of Markerless Dynamic Tumor Tracking-VMAT Using Diaphragm Detection and Respiratory Phase-Based Offset Vector

Authors: Noriko Kishi, Takashi Mizowaki, Mitsuhiro Nakamura, Yukine Shimizu

Affiliation: Kyoto University, Kyoto Univercity, Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University

Abstract Preview: Purpose: To predict tumor positions in markerless dynamic tumor tracking (ML-DTT)-VMAT by compensating for the asynchrony between the tumor and the diaphragm.
Methods: Rotational fluoroscopic X-ray...

First in-Vivo Application of a Novel Precision Small Animal Irradiation Platform with Proton IMPT Delivery and Advanced on-Board Image-Guidance

Authors: Niels Bassler, Jonathan Bortfeldt, Davide Boscaini, Francesco Evangelista, Guyue Hu, Ze Huang, Margarita Kozak, Julie Lascaud, Giulio Lovatti, Eero Lönnqvist, Jasper Nijkamp, Munetaka Nitta, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Babak Sharifi, Brita Singers Sørensen, Peter Thirolf

Affiliation: Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Ludwig-Maximilians Universität, Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital

Abstract Preview: Purpose: To perform the first in vivo application of a novel small animal radiation research platform combining on-board image-guidance with multi-field intensity modulated spot scanning delivery [1] ...

First in-Vivo Proton Radiography Experiments for an Image-Guided Small Animal Irradiation Platform with a TimePix3-Based Detector Setup

Authors: Niels Bassler, Jonathan Bortfeldt, Carlos Granja, Guyue Hu, Margarita Kozak, Julie Lascaud, Kirsten Lauber, Grigory Liubchenko, Jasper Nijkamp, Cristina Oancea, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Brita Singers Sørensen, Matthias Würl

Affiliation: Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital, Advacam

Abstract Preview: Purpose: To apply in-vivo proton radiography (pRad) to aid image registration and treatment plan refinement for a novel precision image-guided small animal proton irradiation platform.

Methods:...

Fully Automated Zero-Shot Organ Segmentation in Male Pelvic MR Images for MR-Guided Radiation Therapy

Authors: Jihun Kim, Jin Sung Kim, Jun Won Kim, Yong Tae Kim, Chanwoong Lee, Jihyn Pyo, Young Hun Yoon

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine

Abstract Preview: Purpose: Although segmentation foundation models have recently demonstrated promising zero-shot performance on natural images, its clinical application to magnetic resonance (MR) images still requires...

Getting in Focus: Review of Current Focal Spot Size Testing Methods with Flat Panel Digital Radiography Detectors

Authors: Matthew R. Hoerner, Maryam Naseri, Mena Shenouda

Affiliation: Yale University School of Medicine, Yale University

Abstract Preview: Purpose:
Historically film has been the gold standard receptor for measurements of x-ray tube focal spot size. Flat Panel Digital Radiography Detectors (FPDRDs) have lower spatial resolution compar...

High-Fidelity Synthetic CT Generation from CBCT for Dibh Breast Cancer Patients Using Shortest Path Regularization

Authors: Manju Liu, Weiwei Sang, Yanyan Shi, Zhenyu Yang, Fang-Fang Yin, Chulong Zhang, Lihua Zhang, Rihui Zhang

Affiliation: Jiahui International Hospital, Jiahui International Hospital, Radiation Oncology, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: This study aims to transform cone-beam computed tomography (CBCT) images acquired from deep inspiration breath-hold (DIBH) breast cancer patients into high-fidelity synthetic CT (sCT) images....

Hypersight® Offline Adaptive Workflow

Authors: Doris Dimitriadis/Dimitriadou, Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Noor Mail, Adam Olson, Tyler Wilhite

Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, UPMC

Abstract Preview: Purpose: The goal of the HyperSight® offline adaptive-workflow is to create a methodical approach to adaptive-radiotherapy (ART) that considers modifications in patient setup and anatomy. Through effi...

Improving 4D-MRI Parameters for Abdominal Tumor Motion Management: A Phantom Study

Authors: Morgan Aire, Krystal M. Kirby, Olivia Magneson, David E. Solis

Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center

Abstract Preview: Purpose: For soft-tissue abdominal tumors, a 4D-MR may provide improved tumor tracking over the clinical standard 4D-CT. This project aims to optimize a clinically available 4D-MR pulse sequence to ac...

Initial Phantom Studies Towards Implementation of Sequential Dual Energy CBCT on an Adaptive Radiotherapy Linac Platform

Authors: James M. Balter, Alexander Moncion, Ikechi S Ozoemelam

Affiliation: University of Michigan

Abstract Preview: Purpose: Sequential dual-energy cone beam computed tomography (DE-CBCT) integrated with an online adaptive platform could potentially improve soft tissue visualization for more accurate anatomical del...

Longitudinal CMR Strain Analysis of Right Ventricular (RV) Function across Aging in Offspring of Baboons Exposed to Moderate Maternal Undernutrition

Authors: Geoffrey D. Clarke, Laura A. Cox, Alexander J Moody, Peter W Nathanielsz, Bowen Yang

Affiliation: Wake Forest University School of Medicine, University of Texas Health Science Center at San Antonio, Texas Biomedical Research Institute

Abstract Preview: Purpose:
Recent studies show diagnostic value of myocardial strain analysis for left ventricular (LV) function using cardiac magnetic resonance imaging (CMR). RV function analysis is more challengi...

Lung Nodule Volume Estimation: Performance of Conventional Energy-Integrating and Cdznte-Photon-Counting CT Using Hybrid Reconstruction Method

Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Luuk J Oostveen, Elsa Bifano Pimenta, Ioannis Sechopoulos, Alessandra Tomal

Affiliation: Radboud University Medical Center, University of São Paulo (USP), Institute of Physics, Universidade Estadual de Campinas. Instituto de Física Gleb Wataghin

Abstract Preview: Purpose: The study evaluated the accuracy and precision of lung nodule volume measurements, specifically solid nodules (SNs) and ground-glass opacities (GGOs) in different imaging settings.
Methods...

Multi-Organ Segmentation of Pelvic Cone-Beam Computed Tomography (CBCT) with Transformer Models to Enhance Adaptive Radiotherapy for Prostate Cancer

Authors: Ming Chao, Thomas Chum, Tenzin Kunkyab, Yang Lei, Tian Liu, Richard G Stock, Hasan Wazir, Junyi Xia, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai

Abstract Preview: Purpose:
This study aims to develop effective strategies for multi-organ segmentation of pelvic cone-beam computed tomography (CBCT) images based on transformer models to facilitate adaptive radiat...

Novel 3D Imaging Systems for Surgical Guidance : Loop-X and Nview S1 in Comparison with O-Arm

Authors: Jia Wang, Vani Yadav

Affiliation: Stanford University

Abstract Preview: Purpose: To evaluate the radiation dose and imaging quality of two novel CBCT X-Ray imaging systems used in spine surgeries.
Methods: CBCT scan of ACR CT and CTDI phantoms was performed to acquire ...

Off- Axis Winston Lutz on C-Arm Linac Using in-House Phantom

Authors: Colton Baley, Bhuvaneswari Narayanan, Niko Papanikolaou, Daniel L. Saenz

Affiliation: UT Health San Antonio, Texas Oncology, University of Texas HSC San Antonio

Abstract Preview: Purpose: To evaluate the accuracy of off-axis winston lutz (WLT) for linac based stereotactic radiosurgery (SRS) treatments using in-house phantom.

Methods: Traditional WLT that uses cone and s...

Prior-Informed Neural Super-Resolution Dosimetry for Radiotherapy QA from Sparse Dosimeter Arrays

Authors: Muhammad Ramish Ashraf, Clinton Gibson, Gregory Szalkowski, Lei Wang, Siqi Wang, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University

Abstract Preview: Purpose: To develop a neural network-based super-resolution framework for enhancing the resolution of sparse dosimetry measurements in patient-specific radiotherapy QA. Sparse detector arrays, such as...

Qualitative Assessment of Low-Dose 4D Cone-Beam CT Protocols for Daily Lung SBRT Patient Alignment

Authors: Yussuf A. Abdelal, Junguo Bian, Michael Delafuente, Sebastien A. Gros, Hyejoo Kang, Luke Layman, M Mahesh, John C. Roeske

Affiliation: Department of Radiology and Medical Imaging, Stritch School of Medicine, Loyola University Medical Center, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Johns Hopkins Univ

Abstract Preview: Purpose: This study evaluates the feasibility of optimizing 4DCBCT imaging protocols for gated lung SBRT, by reducing dose while maintaining the image quality required for accurate patient alignment.<...

Scan Efficiency and Imaging Dose Analysis of Next-Generation Nonstop Gated CBCT for Respiratory Gating Lung Radiotherapy

Authors: Sean L. Berry, Weixing Cai, Laura I. Cervino, Yusuf Emre Erdi, Yabo Fu, Yiming Gao, Daphna Gelblum, Wendy B. Harris, Xiuxiu He, Tianfang Li, Xiang Li, Seng Boh Gary Lim, Jean M. Moran, Mitchell Yu, Hao Zhang

Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Gated CBCT (gCBCT) is commonly employed for respiratory gating lung cancer patients to ensure precise patient setup. However, the scan is time-consuming on C-arm linear accelerators (LINAC) d...

Streamlining Direct-to-Unit Clinical Set-Ups for Radiation Therapy

Authors: Lori Buchholtz, Alison Garda, Chris L. Hallemeier, Kathryn L. Kolsky, Han Liu, Joseph John Lucido, Marisa Schinter, Andrew J. Veres, Sara Walerak

Affiliation: Mayo Clinic

Abstract Preview: Purpose: The C_START initiative aims to streamline and simplify the Direct-to-Unit (DtU) clinical setup and treatment planning process for photon radiation therapy, particularly for emergent cases suc...

Synthetic CT Generation from a Cycle Diffusion Model Based Framework for Ultrasound-Based Prostate HDR Brachytherapy

Authors: Michael Baine, Charles Enke, Yang Lei, Yu Lei, Ruirui Liu, Su-Min Zhou

Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Radiation Oncology, University of Nebraska Medical Center

Abstract Preview: Purpose: This study presents a framework for generating synthetic CT images using a Cycle Diffusion model, which can be utilized to enhance needle conspicuity in ultrasound-guided prostate HDR brachyt...

Synthetic Vs. Conventional Planar Imaging: Performance and Clinical Feasibility

Authors: Jennifer Kwak, Chelsea Manica, Justin K. Mikell, Michael Silosky, Wendy Siman

Affiliation: Washington University School of Medicine in St. Louis, University of Colorado Anschutz Medical Campus, School of Medicine, Rocky Vista University

Abstract Preview: Purpose:
This study evaluates synthetic planar imaging (synP) from SPECT projections against conventional planar imaging, focusing on detectability, spatial resolution, and feasibility. SynP allows...

Testing the Performance of Rbe Models Using a Comprehensive Panel of Pancreatic Cancer Cell Lines

Authors: Joana Antunes, Scott James Bright, David B. Flint, Mojtaba Hoseini-Ghahfarokhi, Mandira Manandhar, Poliana Marinello, Gabriel O. Sawakuchi, Tingshi Su

Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Laboratory of Instrumentation and Experimental Particle Physics; Faculty of Science of University of Lisbon, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, MD Anderson Cancer Center

Abstract Preview: Purpose: To study the accuracy of relative biological effectiveness (RBE) models to predict the RBE of a comprehensive panel of pancreatic cancer cell lines.

Methods: Clonogenic cell survival w...

Time-Resolved CBCT: A Novel Solution for Motion Management

Authors: Bulent Aydogan, Xiaochuan Pan, Erik Pearson, Zheng Zhang

Affiliation: The University of Chicago

Abstract Preview: Purpose: Motion management remains one of the significant challenges in external beam radiation therapy (RT). We are developing time-resolved cone-beam computed tomography (trCBCT) for imaging during ...

Treatment Dose Reconstruction of Digitized Deliveries on Reflexion X1 System Based on Megavoltage Imager and Dose Monitor Chamber

Authors: Angela J Da Silva, Andrew Groll, Gopinath Kuduvalli, Thomas Laurence, David W. Meer, Manoj Narayanan, Mingshan Sun, Don Vernekohl, Ray Yang

Affiliation: RefleXion Medical

Abstract Preview: Purpose: To implement post-treatment review of delivered dose fractions on RefleXion X1 accounting for independent detection of transmitted beamlets and transient dose fluctuations of individual pulse...

Tumor Density on Time-Weighted Mid-Position Images for Thoracic Tumors

Authors: Katrinus Keijnemans, Eric S. Paulson, An Tai

Affiliation: Department of Radiotherapy, University Medical Center Utrecht, Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Time-weighted mid-position images (MidPs), derived from four-dimensional computed tomography (4DCT) via deformable image registration (DIR), are frequently selected for treatment planning due...

Twin Table-Tilt Imaging: Rapid Metal Artefact Reduction Intraoperative CBCT Imaging during Pedicle Screw Spinal Fixation

Authors: Owen Thomas Dillon, Andrew Kanawati, Tess Reynolds

Affiliation: Westmead Hospital, Image X Institute, Faculty of Medicine and Health, The University of Sydney

Abstract Preview: Purpose: Metal artefacts from implanted hardware and surgical tools remain a limitation for widespread adoption of intraoperative CBCT imaging. Gantry-based non-circular imaging trajectories have emer...