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Results for "coefficient variation": 50 found

Achieving Consistent Calcium Score in Lung Cancer Screening: Influence of Cardiac Phases

Authors: Emi Ai Eastman, Chao Guo, Christina Lee, Xinhua Li, Alexander W. Scott, Yifang (Jimmy) Zhou

Affiliation: Cedars-Sinai Medical Center

Abstract Preview: Purpose:
Smoking is one of the risk factors for coronary artery disease. It is desirable to estimate the coronary artery calcification (CAC), a key biomarker for atherosclerosis and cardiovascular ...

An Analytical Framework to Quantify the Effect Obstructing Anatomical Features in Intrafractional Spectral Imaging Using a Dual-Layer Kv Imager

Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Marios Myronakis

Affiliation: Medical Physics Department, Medical School, University of Thessaly, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory

Abstract Preview: Purpose:
Dual-layer kV imager (DLI) architecture enables the capability for single-shot dual-energy (DE) intrafraction imaging. As noise from individual DLI layers are primarily uncorrelated, simpl...

An Image Registration-Based Motion Correction Procedure to Recover Joint Cardiac and Respiratory Motion from Respiratory 4DCT

Authors: Phillip Cuculich, Geoffrey D. Hugo, Xiwen Li, Michael T. Prusator, Clifford Robinson, Pamela Samson, Xue Wu

Affiliation: Washington University School of Medicine in St Louis, Washington University School of Medicine in St. Louis, University of Utah, WashU Medicine

Abstract Preview: Purpose: Stereotactic arrhythmia radiotherapy (STAR) requires compensation for both respiratory and cardiac motions of the heart. Respiratory 4DCT scans implicitly include cardiac motion and cycle-to-...

Analysis of Inter-Organ Noise Variability for Clinical CT Images across 3133 Image Series

Authors: Lavsen Dahal, Francesco Ria, Ehsan Samei, Justin B. Solomon, Liesbeth Vancoillie, Yakun Zhang

Affiliation: Duke University, Carilion Clinic, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Clinical diagnostic task-based optimization of CT procedures require precise and organ-specific assessments. This study investigates inter-organ noise variability to highlight the limitations...

Applicability of Online Dose Measurement in Trilogy Linear Accelerators: Using Target Current Pulse Counting Method

Authors: Daming LI, Jinsen Xie, Zhe Zhang

Affiliation: Peking University Shenzhen Hospital Radiotherapy Department, School of Nuclear Science and Technology, University of South China

Abstract Preview: Purpose:
This study aims to investigate the feasibility of online dose measurement of the Trilogy linear accelerator output based on target current pulse signals.
Methods:
A data acquisition ...

Commissioning Silicone Tissue-Compensating Bolus for Electron Beam Therapy

Authors: Carla D. Bradford, Linda Ding, Yansong Geng, Alan Hartford, I-Lin Kuo, Salvatore LaRosa, Joshua N Wancura

Affiliation: University of Massachusetts Chan Medical School

Abstract Preview: Purpose: When treating nasal skin cancers, electron beam radiotherapy dose distributions can be improved by using custom bolus to compensate for uneven surfaces. Here we describe our experience commis...

Comparative Analysis of Soft Tissues and 3D Printing Materials Using Euclidean Distance for Linear Attenuation Coefficient

Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Elsa Bifano Pimenta

Affiliation: University of São Paulo (USP), Institute of Physics

Abstract Preview: Purpose: This study evaluates the similarity between the linear attenuation coefficients of soft tissues and 3D printing materials in diagnostic imaging range using the Euclidean distance approach.

Comprehensive Evaluation of High-Performance Cone-Beam Computed Tomography on C-Arm and Ring-Gantry Linacs for Adaptive Radiation Therapy

Authors: Laura I. Cervino, Karen Episcopia, Hsiang-Chi Kuo, Sangkyu Lee, Seng Boh Gary Lim, Shih-Chi Lin, Grace Tang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: This study evaluated the performance of the HyperSight Cone-Beam Computed Tomography (CBCT) system on a TrueBeam C-arm LINAC (TB) and two Ethos ring-gantry LINACs (ES) for adaptive radiation ...

Conversion Coefficients from Hp(10) to Organ and Effective Doses for Medical Staff Involved in Fluoroscopically Guided Interventional Procedures

Authors: Stephen Balter, Haegin Han, Cari M Kitahara, Taeeun Kwon, Choonsik Lee, Martha S Linet, Donald L. Miller

Affiliation: Columbia University Medical Center, National Cancer Institute, Food and Drug Administration

Abstract Preview: Purpose: Staff in fluoroscopically guided interventional (FGI) procedures are exposed to radiation. Inhomogeneous radiation fields and variability in procedural conditions make it challenging to deriv...

Decreasing the Dependence of CT Number on the Position in the Field-of-View Using Photon Counting Detector CT

Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik

Affiliation: Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose: The dependence of CT number on position in the field-of-view (FOV) imposes challenges in radiotherapy treatment planning. This study aims to decrease this dependence using photon counting det...

Dependency of CT Number on Position in the Field-of-View for Single- and Multi-Energy Images Acquired with Energy-Integrating-Detector and Photon-Counting-Detector CT Scanners

Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik

Affiliation: Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose: To assess the dependency of CT numbers on position in the field-of-view (FOV) using single-energy (SE) and dual-energy (DE) images and energy-integrating detector (EID) and photon-counting de...

Diffusion-Weighted MRI: An Early Biomarker for Treatment Response in MR-Guided Treatment of Rectal Cancer

Authors: Huiming Dong, Jonathan Pham, X. Sharon Qi, Ann Raldow

Affiliation: Department of Radiation Oncology, University of California, Los Angeles

Abstract Preview: Purpose: The study aimed to investigate longitudinal apparent diffusion coefficient (ADC) as an early biomarker of treatment response in patients with locally advanced rectal cancer (LARC) undergoing ...

Do We Need Pediatric-Specific Models for Radiotherapy Auto-Contouring? a Comparative Study of Pediatric and Adult-Trained Tools

Authors: Gregory T. Armstrong, James E. Bates, Christine V. Chung, Lei Dong, Ralph Ermoian, Jie Fu, Christine Hill-Kayser, Rebecca M. Howell, Meena S. Khan, Sharareh Koufigar, John T. Lucas, Thomas E. Merchant, Taylor Meyers, Tucker J. Netherton, Constance A. Owens, Arnold C. Paulino, Sogand Sadeghi

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, St. Jude Children's Research Hospital, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, St. Jude Children’s Research Hospital, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, University of Washington/ Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences

Abstract Preview: Purpose: Clinical workflows often rely on auto-segmentation tools trained on adult data, which may exhibit suboptimal performance in pediatric imaging due to inherent anatomical variations and smaller...

Dosimeteric Parameter Evaluation of Digital Polycrystalline Semiconductor Dosimeters for Quality Assurance of High-Dose-Rate Brachytherapy

Authors: Woong Cho, Jin-Beom Chung, Moo-Jae Han, Sang Won Kang, Boram Lee

Affiliation: Department of Radiation Oncology, Seoul National University Boramae Medical Center, Department of Radiation Oncology, Seoul National University Bundang Hospital, Department of Radiation Oncology, Inha University Hospital

Abstract Preview: Purpose: This study aims to establish a digital quality assurance (QA) system for high-dose-rate (HDR) brachytherapy by evaluating self-developed polycrystalline semiconductor dosimeters (PSDs).
Me...

Efficient Monte Carlo Proton Dose Calculation Using Denoising Diffusion Probabilistic Models

Authors: Chieh-Ya Chiu, Shen-Hao Li, Hsin-Hon Lin, Shu-Wei Wu

Affiliation: Department of Medical Imaging and Radiological Sciences, Chang Gung University, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital Linkou

Abstract Preview: Purpose: Monte Carlo simulation enables precise calculation of dose distribution in proton therapy through tracing the radiation particles with patient tissues. However, achieving clinical-level preci...

Evaluating Necessity of Patient-Specific Deep Learning-Based Auto-Segmentation for Improved Adaptation for Abdominal Tumors

Authors: Asma Amjad, Renae Conlin, Eric S. Paulson, Christina M. Sarosiek

Affiliation: Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: In an effort to improve contouring accuracy for abdominal MR guided online adaptive radiotherapy (MRgOART), patient-specific deep learning-based auto-segmentation (PS-DLAS) has been proposed....

Evaluating the Impact of Bladder Volume on Small Bowel Dose Constraints in Prostate Cancer Patients with Nodal Involvement: Assessing the Efficacy of a 'half-Full Bladder' Guideline

Authors: Neha Devi, Deon M. Dick

Affiliation: Jaeger Corporation

Abstract Preview: Purpose: To evaluate the impact of bladder volume variation on small bowel dose in prostate cancer patients with nodal involvement and assess the efficacy of a 'half-full bladder' guideline for minimi...

Evaluation of Phosphorus-32 Source Uniformity Using Python Algorithm and Monte Carlo Simulation

Authors: Ana Laura Burin, Ilca Marli Moitinho Amaral Medeiros, Priscila Santos Rodrigues, Maria Elisa Chuery Martins Rostelato, Sabrina Spigaroli Sgrignoli, Ana Catarina Koka de Souza Silva, Carla Daruich Souza, Cristhian Ferreira Talacimon, Lara El Hajj Teodoro, Carlos Alberto Zeituni

Affiliation: IPEN - USP, IPEN - Instituto de Pesquisas Energéticas e Nucleares

Abstract Preview: Purpose: The uniform distribution of phosphorus-32 (32P) in beta sources is essential to ensure the accuracy of radiotherapy treatments, such as those for paravertebral cancer. This study evaluated th...

Evaluation of the Hyperscint RP-200 Plastic Scintillation Dosimetry System for Reference Dosimetry in Ultra-High Dose Rate Electron Beam Therapy: A Comparative Study

Authors: Julie Colnot, Eric Deutsch, Christelle Huet, Danahé LeBlanc, Pauline Maury, Charlotte Robert, Imane Saïd Mansour, Cathyanne Schott, Francois Therriault-Proulx

Affiliation: INSERM U1030, Gustave Roussy, University Paris-Saclay, LDRI, IRSN, Medscint, THERYQ / INSERM U1030, Gustave Roussy, University Paris-Saclay, Université Paris-Saclay, Gustave Roussy, Inserm U1030, Radiothérapie Moléculaire et Innovation Thérapeutique

Abstract Preview: Purpose: FLASH radiotherapy, using ultra-high dose rates (UHDR, >100 Gy/s), spares healthy tissues while maintaining tumor control compared to conventional radiotherapy (CONV). However, UHDR dosimetry...

Expert Verification of AI-Generated Cardiac Substructures and Dosimetric Differences between Auto-Contoured and Manually Delineated Contours

Authors: Stephen R. Bowen, Richard Cheng, Kylie Kang, Janice Kim, Ana Paula Santos Lima, Dominic A. Maes, Juergen Meyer, Karen Ordovas, Kerry Reding

Affiliation: Department of Radiation Oncology, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiology, University of Washington, Division of Cardiology, University of Washington, Department of Biobehavioral Nursing and Health Informatics, School of Nursing, University of Washington

Abstract Preview: Purpose: Artificial intelligence (AI)-based auto-segmentation tools can increase the efficacy and reproducibility of radiotherapy (RT) treatment planning. This study evaluates the quality of AI-genera...

Foundation Models with Balanced Data Sampling Enhance Auto-Segmentation for Cardiac Substructures

Authors: Chloe Min Seo Choi, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu

Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Cardiac substructure irradiation predisposes patients for poor outcomes in thoracic radiation therapy. A deep learning model was developed to segment the cardiac substructures invariant to co...

From Concept to Clinic: A Phase-Based Approach for Implementing Auto-Segmentation in Radiation Therapy

Authors: Elizabeth L. Covington, Robert T. Dess, Charles S. Mayo, Michelle L. Mierzwa, Dan Polan, Jennifer Shah, Claire Zhang

Affiliation: University of Michigan, Department of Radiation Oncology, University of Michigan

Abstract Preview: Purpose: Auto-segmentation improves contour consistency and standardization in radiation therapy but may introduce variations from current practices, potentially impacting treatment outcomes and toxic...

GPU-Accelerated Beamlet and Full Dose Calculations for Efficient Radiation Therapy Planning

Authors: Girish Bal, Jan Kralj, Ayan Mitra, PhD, Ling Shao, Matjaz Subic, Yevgen Voronenko

Affiliation: RefleXion Medical, Cosylab

Abstract Preview: Purpose: This work enhances the efficiency of radiation therapy treatment planning by optimizing the beamlet dose matrix and full patient dose computations using GPU acceleration. The Collapsed-Cone C...

Generation of Patient-Specific Phantom for Head & Neck Proton Therapy Based on Xcat

Authors: Cheng-En Hsieh, Shen-Hao Li, Hsin-Hon Lin, Shu-Wei Wu, An-Ci Yang

Affiliation: Department of Medical Imaging and Radiological Sciences, Chang Gung University, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital Linkou

Abstract Preview: Purpose:
The aim of this study is to develop a framework of generating patient-specific phantom tailored for head and neck proton therapy. From these phantoms, digital reference objects based on th...

Gradient-Based Radiomics for Outcome Prediction and Decision-Making in Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR): A Preliminary Study

Authors: Michael Dohopolski, Jiaqi Liu, Hao Peng, Robert Timmerman, Zabi Wardak, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
This study introduces a gradient-based radiomics framework to enhance outcome prediction in Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR) for brain metastases...

Icrp Mesh-Type Reference Computational Phantoms Representing Pregnant Women and Fetuses

Authors: Wesley E. Bolch, Chansoo Choi, Chan Hyeong Kim, Suhyeon Kim, Bangho Shin, Yeon Soo Yeom

Affiliation: Hanyang University, University of Florida, 2) Department of Radiation Convergence Engineering, Yonsei University

Abstract Preview: Purpose: Task Group 103 of International Commission on Radiological Protection (ICRP) recently released new-generation adult and pediatric mesh-type reference computational phantoms (MRCPs) via ICRP P...

Impact analysis of effective dose conversion factors from CT scanner models

Authors: Max Chen, Sean Marquardt, Ben Yang, Kai Yang

Affiliation: Cary Academy, Massachusetts General Hospital, Winchester High School

Abstract Preview: Purpose: To analyze the impact of scanner model variation on the effective dose conversion factor (“k-factor”), which is most commonly used for CT effective dose calculation.

Methods: The stand...

Improving Segmentation Precision in Prostate Cancer Adaptive Radiotherapy with the Intentional Deep Overfit Learning (IDOL) Approach

Authors: Seungryong Cho, Donghyeok Choi, Joonil Hwang, Byung-Hee Kang, Jin Sung Kim, Eungman Lee, Younghee Park

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, KAIST, Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Ewha Womans University of Medicine

Abstract Preview: Purpose: Radiation therapy (RT) is critical for cancer treatment, but changes in tumor size and shape during therapy challenge precise dose delivery. Adaptive radiation therapy (ART) addresses these v...

Integrating Foundation Model with Self-Supervised Learning for Brain Lesion Segmentation with Multimodal and Diverse MRI Datasets

Authors: Zong Fan, Fan Lam, Hua Li, Rita Huan-Ting Peng, Yuan Yang

Affiliation: University of Illinois at Urbana Champaign, University of Illinois at Urbana-Champaign, Washington University School of Medicine, University of Illinois Urbana-Champaign

Abstract Preview: Purpose: Accurate lesion segmentation in MRI is critical for early diagnosis, treatment planning, and monitoring disease progression in various neurological disorders. Cross-site MRI data can alleviat...

Investigating the Use of a DWI Phantom for Routine QA of an MR-Linac at Room Temperature

Authors: Nicholas Carlson, Joel J. St-Aubin

Affiliation: University of Iowa Hospitals and Clinics, University of Iowa

Abstract Preview: Purpose: To establish baselines metrics and determine longitudinal accuracy and reproducibility of Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC) values for a 1.5T Elekta Un...

Investigation into the Robustness of Spine Stereotactic Body Radiotherapy Plans to Patient Setup Errors

Authors: Yukio Fujita, Syoma Ide, Fumiki Ito, Kei Ito, Satoshi Kito, Keiko Murofushi, Yujiro Nakajima, Yuhi Suda, Kentaro Taguchi, Naoki Tohyama, Fumiya Tsurumaki, Riku Watanabe

Affiliation: Komazawa University Graduate School, Komazawa University, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital

Abstract Preview: Purpose: Spine stereotactic body radiotherapy (SBRT) demands high precision due to the target's proximity to the spinal cord and steep dose gradients, which complicate treatment planning. Consequently...

Investigation of Low Iodine Concentration Detectability of Dual-Energy CT Imaging Using a Customized 3D Printed Phantom

Authors: Michalis Aristophanous, Laura I. Cervino, Maria F. Chan, Puneeth Iyengar, Hsiang-Chi Kuo, Nancy Y Lee, Xiang Li, Seng Boh Gary Lim, Usman Mahmood, Jean M. Moran, Jason Ocana

Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: To determine the limits of iodine concentration detection (LOD) and quantification (LOQ) in dual-energy computed tomography using a 3D printed phantom while considering different background, ...

LD-V1 Film Characterization for MV Beam Quality

Authors: Ruiming Chen Edmondson, Darwin Abraham Garcia, James A. Kavanaugh, Joseph John Lucido

Affiliation: Mayo Clinic

Abstract Preview: Purpose: Characterize the dose response and reproducibility of a low-dose film for 6 MV photon beam and assess the film’s energy dependence between kV and MV energies.
Methods: A single 8’x10’ LD-V...

Lung Mass Variability in Clinical Chest CT Imaging with Automatic Contouring Tool

Authors: Yasaman Anbari, Srinivas Cheenu Kappadath, Benjamin P. Lopez

Affiliation: University of Houston, UT MD Anderson Cancer Center

Abstract Preview: Purpose: To improve lung dosimetry for 90Y-radioembolization planning, CT-based techniques have been proposed for patient-specific lung mass estimation instead of assuming nominal 1 kg lung masses. He...

Multi-Center Diffusion-Weighted MRI Validation for 0.35T MR-Linac: A Repeatability and Reproducibility Study

Authors: Tess Armstrong, Nema Bassiri, Alonso N. Gutierrez, Michael Kasper, Natalia Lutsik, Eric Mellon, Kathryn E. Mittauer, Siamak P. Nejad-Davarani, Shyam Pokharel, Suresh Rana, Hui Wang, Joseph Weygand

Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Miami Cancer Institute, Baptist Health South Florida, ViewRay, Inc., Miami Cancer Institute, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Department of Radiation Oncology, University of Miami

Abstract Preview: Purpose: Radiation treatments on the MR-linac (MRL) enable daily acquisition of anatomical and physiological images for adaptive treatment planning. The apparent diffusion coefficient (ADC) estimated ...

Multi-Institutional Analysis of CT Dose Index Variability and Radiomics Features

Authors: Caroline Chung, Michael Knopp, Stephen F. Kry, Hunter S. Mehrens, John Rong

Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, University of Cincinnati

Abstract Preview: Purpose: To evaluate the variability of CT dose index (CTDIvol) and radiomics features across a large cohort of radiotherapy simulation CT scans from multiple institutions.
Methods: Three IROC phan...

Optimizing Dosimetry in Rpt Clinics: Tackling Initial Hurdles and Ensuring Image Accuracy.

Authors: Siju C. George, Alonso N. Gutierrez, Vivek Mishra, Ranjini P. Tolakanahalli

Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute

Abstract Preview: Purpose: This presentation focuses on optimizing dosimetry in RPT clinics by tackling initial setup challenges and ensuring the accuracy of SPECT/CT imaging for dosimetry. It will address the qualific...

PCA-Based Future Frame Prediction for Real-Time MRI-Guided Radiotherapy

Authors: B. Gino Fallone, Gawon Han, Keith D. Wachowicz, Mark G. Wright, Eugene Yip, Jihyun Yun

Affiliation: Medical Physics Division, Department of Oncology, University of Alberta, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta, Medical Physics Division, Department of Oncology, University of Alberta and Department of Medical Physics, Cross Cancer Institute, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta; MagnetTx Oncology Solutions, www.magnetTX.com

Abstract Preview: Purpose: MRI-radiotherapy hybrid systems can guide the therapeutic beam, dynamically adjusting to a moving tumor in real-time. However, there is a time delay from imaging and beam control, requiring p...

Predicting CBCT-Based Adaptive Radiation Therapy Session Duration Using Machine Learning

Authors: Leslie Harrell, Sanjay Maraboyina, Romy Megahed, Maida Ranjbar, Xenia Ray, Pouya Sabouri

Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), University of California San Diego

Abstract Preview: Purpose: Real-time adaptive radiation therapy (ART) dynamically modifies patients’ treatment plan during delivery to account for anatomical and physiological variations. Addressing ART planning time v...

Repeatability of Quantitative 3D T1ρ Imaging in Head and Neck Cancer

Authors: Sandeep Panwar Jogi, Nancy Lee, Ricardo Otazo, Ramesh Paudyal, Qi Peng, Akash Shah, Amita Shukla-Dave, Can Wu

Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center

Abstract Preview: Purpose: Quantitative T1ρ imaging provides enhanced tissue characterization beyond standard T1 and T2 parameters, potentially supporting early-stage longitudinal monitoring of head and neck cancer. Th...

Robustness of Jacobian-Based and HU Change-Based CT Ventilation Imaging to Respiratory Amplitude Variations: A Study Using a Custom Phantom with Respiratory Amplitude Control

Authors: Tatsuya Fujisaki, Hiraku Fuse, Shin Miyakawa, Hiroki Nosaka, Masato Takahashi, Kenji Yasue

Affiliation: Ibaraki Prefectural University of Health Sciences

Abstract Preview: Purpose: This study aimed to evaluate the robustness of Jacobian-based and HUchange-based CT ventilation imaging (CTVI) against respiratory amplitude variations using a custom-designed alveolar phanto...

Sensitivity of CT Ventilation Imaging to Image Acquisition and Reconstruction Parameters: A Phantom Study

Authors: Hilary Louisa Byrne, Paul J. Keall, John Kipritidis, Jeremy Lim

Affiliation: Northern Sydney Cancer Centre, University of Sydney, Image X Institute, Faculty of Medicine and Health, The University of Sydney

Abstract Preview: Purpose:
Non-contrast CT ventilation imaging (CTVI) has been developed as a cost-effective and accessible alternative to PET/SPECT V/Q imaging for visualizing lung function. However, the sensitivit...

Spatially Informed Auto-Segmentation of Cardiac Nodes for Radiotherapy Treatment Planning

Authors: Ming Dong, Carri K. Glide-Hurst, Joshua Pan, Nicholas R. Summerfield

Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Radiation dose to the cardiac nodes is more strongly associated with conduction disorders and arrythmias than whole heart (WH) metrics. However, node segmentation is challenging due to comple...

Streamlining Quality Control for Radiographic and Fluoroscopic Systems

Authors: Caroline Cheney, Patricia G Collins, Allen R. Goode, Preston Le, Andrew M. Polemi, Angela Snyder

Affiliation: UVA Health, Atirix Medical Systems

Abstract Preview: Purpose: Optimize ongoing quality control (QC) for radiographic (DR) and fluoroscopic (FL) systems by identifying metrics most sensitive to hardware disruptions among regional noise, pooled noise, sig...

Uncertainties on Synthetic-CT Generation from CBCT: Another Layer of Complexity in Abdominal Adaptive Radiotherapy

Authors: Laura I. Cervino, Wendy B. Harris, Paulo Quintero, Hao Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: To evaluate the impact of the prediction uncertainty from CBCT-based synthetic CT (sCT) generation in abdominal adaptive radiotherapy.

Methods: CT and CBCT images from 65 abdominal pat...

Uncertainty Analysis for Effective Dose Conversion Factors in CT

Authors: Renxin Chu, Jelena Mihailovic, Kai Yang, Lifeng Yu, Da Zhang

Affiliation: Massachusetts General Hospital, Mayo Clinic, Boston Children's Hospital, UVA Health University Hospital, University of Missouri Health Care

Abstract Preview: Purpose:
A frequently used method to estimate effective dose (ED) in CT is by multiplying the dose length product (DLP) by a conversion factor, known as k-factor. The k-factor in this method is sus...

Uncertainty in Contralateral Breast Dose Reconstruction for Breast Cancer Radiotherapy Patients in the United States between 1990 and 2012

Authors: Amy Berrington de Gonzalez, David Borrego, Rochelle Curtis, Gretchen L Gierach, Jae Won Jung, Choonik Lee, Choonsik Lee, Matthew Mille, Lene Veiga, Jacqueline Vo

Affiliation: University of Michigan, East Carolina University, Radiation Protection Division, Office of Radiation and Indoor Air, U.S. Environmental Protection Agency, National Cancer Institute, Institute of Cancer Research

Abstract Preview: Purpose: Radiotherapy is vital for treating breast cancer, but its long-term health effects remain a concern. Accurate dose reconstruction is crucial for evaluating risks in retrospective epidemiologi...

Using Multi-Peak Reconstructions for Dosimetry of Fast and Quantitative Lutetium-177 SPECT/CT

Authors: Julia Brosch-Lenz, Munir Ghesani, Francesc Massanes, Michael Morris, Babak Saboury, Eliot Siegel, Alexander Hans Vija

Affiliation: Institute of Nuclear Medicine, Siemens Medical Solutions USA Inc., Molecular Imaging

Abstract Preview: Purpose: Quantitative imaging of the radiopharmaceutical distribution is crucial for treatment evaluation and dosimetry. However, as patient numbers for Lutetium-177-(177Lu)-labelled therapies continu...

Validation and Benchmarking of Mirdct Software for Organ Dose Estimation in Routine CT Protocols

Authors: Jared Baggett, Wesley E. Bolch, Lukas M. Carter, Robert Joseph Dawson, Laura Dinwiddie, Gunjan Kayal, Adam Leon Kesner, Harry Marquis, Juan Camilo Ocampo Ramos, Stefan Wehmeier

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, University of Florida, MD Anderson

Abstract Preview: Purpose: Accurate organ dose estimation in computed tomography (CT) has gained attention due to the increasing global utilization of CT imaging. MIRDct, a specialized CT dosimetry software, has recent...

Validation of Synthetic CT-Based Online Monitoring for Adaptive Proton Therapy

Authors: Ozgur Ates, Chin-Cheng Chen, Chia-Ho Hua, Matthew J. Krasin, Thomas E. Merchant

Affiliation: St. Jude Children's Research Hospital

Abstract Preview: Purpose: To validate the use of synthetic CTs generated from CBCT images for online monitoring, ensuring accurate and reliable daily plan quality assessments in adaptive proton therapy (APT).
Metho...