Authors: Aaron Conard, Victoria Croog, Marie Gurka, Lan Lin
Affiliation: Johns Hopkins University
Abstract Preview: Purpose:
This study evaluates the utility of the Active Breathing Coordinator (ABC) and Surface Guided Radiation Therapy (SGRT) techniques in implementing Deep Inspiration Breath Hold (DIBH) for le...
Authors: Yufeng Cao, Arun Gopal, Kai Huang, Kai Wang
Affiliation: Department of Radiation Oncology, University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland Medical Center, University of Maryland, Baltimore
Abstract Preview: Purpose: The treatment of left-sided breast tumors poses significant concerns regarding the risk of radiation-induced damage to nearby organs, particularly the heart. In clinical practice, breath-hold...
Authors: Charmainne Cruje, Maria Dumol, Nawroz Fatima, Marisa Finlay, Kalaina Johnson, Raman Mohla, Jasleen Uppal
Affiliation: Trillium Health Partners, Carlo Fidani Regional Cancer Centre
Abstract Preview: Purpose: To evaluate the robustness of a breast SBRT protocol in achieving target coverage by utilizing online- and retrospectively-matched CBCT-to-CT images.
Methods: The first pilot patient was s...
Authors: Hui-Shan Jian, Yu-Ying Lin
Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou
Abstract Preview: Purpose: The image quality assurance of mammographic images is crucial for correct diagnosis. To develop and validate an explainable deep-learning classifier for phantom image quality assessment of di...
Authors: Scott James Bright, Vered Domankevich-Bachar, Mandira Manandhar, Poliana Marinello, Yogesh Rai, Marco Freitas Reis, Alexandre Rubinstein, Gabriel O. Sawakuchi, Ronen Segal, Walison Augusto Silva Brito, Mark Wasley, Amy Wu
Affiliation: MD Anderson Cancer Center, Alpha Tau Medical Ltd, Alpha Tau Medical LTD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Immunologically cold breast cancers are aggressive and difficult to treat due to their lack of immune cell infiltration. The combination of high-LET radiation with DNA repair inhibitors offer...
Authors: Nana Akosua O. Adomako, Evangeline Dorleagbenu, Victor E. Ekpo, Fatima Issaka, Abigail N.M. Quaye
Affiliation: Tema General Hospital, Pink Africa Foundation, Korle Bu Teaching Hospital, Methodist University, Medical Equipment and Ancillary Services
Abstract Preview: Purpose: This preliminary study evaluates the effectiveness of breast cancer awareness programs for teenagers in Tema, Ghana. In Ghana, breast cancer poses a significant public health challenge. There...
Authors: Sen Bai, Guyu Dai, Dong Gao, Lecheng Jia, Guangjun Li, Yanfang Liu, Ying Song, Qing Xiao, Wei Zhang
Affiliation: United Imaging Healthcare, West China Hospital of Sichuan University, Shenzhen United Imaging Research Institute of Innovative Medical Equipment
Abstract Preview: Purpose:
Electronic portal imaging device (EPID) is currently the most widely used in-vivo dosimetry (IVD) device. However, the effective detector area shortage hinders further applications. This s...
Authors: Michael Dohopolski, Xuejun Gu, Hao Jiang, Steve B. Jiang, Christopher Kabat, Jingying Lin, Weiguo Lu, Michael Tang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Neuralrad LLC, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: To streamline access to clinical data stored in Oncology Information Systems such as MOSAIQ or ARIA, we developed an AI-powered chatbot capable of querying, summarizing, and interactively ans...
Authors: Wesley A. Belcher, Aidan Burke, Matthew Green, Taylor Stamey
Affiliation: ECU Health, East Carolina University Brody School of Medicine
Abstract Preview: Purpose: The purpose of this study was to determine the effect of using deep inhalation breath hold (DIBH) vs. free breathing (FB) and intensity-modulated radiation therapy (IMRT) vs. 3D for right-sid...
Authors: Laura A. Doyle, Amy S. Harrison, Allyson P Koecher, Jackson D Reeves, Lindsay B Romak
Affiliation: Christiana Care
Abstract Preview: Purpose: Surface guided radiation therapy (SGRT) is increasingly utilized in radiation oncology, allowing for transition away from permanent skin marks to SGRT-based daily treatment setup. Following i...
Authors: Nrusingh C. Biswal, Sally Cheston, Sung-Woo Lee, Weiguang Yao, Baoshe Zhang
Affiliation: Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: The deep inspiration breath-hold (DIBH) technique in left breast radiation reduces doses to critical organs such as the heart, left lung, and left anterior descending artery (LAD). With the a...
Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...
Authors: Adi Robinson, Michael J. Tallhamer
Affiliation: Centura Health, AdventHealth Orlando
Abstract Preview: Purpose: This study aims to evaluate the integration of Cherenkov imaging into radiation therapy practices, focusing on its utility in enhancing treatment precision, patient safety, and clinical decis...
Authors: Li Chen, Shouliang Ding, Xiaoyan Huang, Lecheng Jia, Hua Li, Hongdong Liu, Yanfei Liu, Zun Piao, Guangyu Wang
Affiliation: State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Shenzhen United Imaging Research Institute of Innovative Medical Equipment
Abstract Preview: Purpose: Optimal radiotherapy planning is challenging, influenced by anatomical factors such as surrounding organs and tumor characteristics, which complicate dose distribution and target coverage. Wh...
Authors: Rajeev Gupta, Shriram Ashok Rajurkar, Teerthraj Verma
Affiliation: King George's Medical University, King George's Medical University, UP
Abstract Preview: Purpose:
The volunteer deep inspiration breath hold (vDIBH) technique is used to reduce the heart dose in left breast cancer radiotherapy. Many times, it is faced that despite rigorous exercise and...
Authors: Samuel O. Adeneye, Victoria Susan Ainsworth, Azeezat Ajose, Stephen M. Avery, Munir Awol, Kavuma Awusi, Onyinye Balogun, Rohini Bhatia, Frank Chinegwundoh, Jumaa Dachi Kisukari, Curtiland Deville, Katy Graef, Yao Hao, M. Saiful Huq, Luca Incrocci, Adedayo O. Joseph, Solomon Kibudde, Joerg Lehmann, Heng Li, Abba Mallum, Thokozani Mkhize, Twalib Ngoma, Wilfred Ngwa, Christopher F. Njeh, Janine Simons, William Swanson, Maureen Bilinga Tendwa, Joseph Weygand, Krishni Wijesooriya
Affiliation: Uganda Cancer Institute, Johns Hopkins University, BIO Ventures for Global Health, Weill Cornell Medicine, Washington University School of Medicine, South Africa Health Product Regulatory Authority, University of Pennsylvania, University of Massachusetts Lowell, NSIA-LUTH Cancer Center, University of Lagos, Indiana University School of Medicine, Department of Radiation Oncology, Erasmus Medical Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, Addis Ababa University, Ocean Road Cancer Institute, Emory University, Barts Health NHS Trust, Inkosi Albert Luthuli Central Hospital, Lagos University Teaching Hospital, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, University of Virginia School of Medicine, University of Newcastle
Abstract Preview: Purpose: Sub-Saharan Africa continues to face a critical shortage in radiotherapy resources, exacerbating the region’s growing cancer burden. One potential strategy that can partially offset this prob...
Authors: Chloe Min Seo Choi, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Cardiac substructure irradiation predisposes patients for poor outcomes in thoracic radiation therapy. A deep learning model was developed to segment the cardiac substructures invariant to co...
Authors: Md. Yousuf Ali, Parvin Akhter Banu, Ehteshamul Hoque, Qazi Mushtaq Hussain, Md Jobairul Islam, Md. Abdul Mannan, Sadia Afrin Sarah, Mostafa Aziz Sumon, Ahammad Al Mamun Sweet, AFM Kamal Uddin
Affiliation: Labaid Cancer Hospital & Superspeciality Centre
Abstract Preview: Purpose: Radiotherapy for left-sided breast cancer can induce cardiac injury. Deep Inspiration Breath Hold (DIBH) is a technique that minimizes cardiac exposure during treatment. This study compares d...
Authors: Jianrong Dai, Jun Dang, Enzhuo Quan, Yong Sang, Jianan Wu
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, National Cancer Center / National Clinical Research Center for Cancer / Cancer Hospital & Shenzhen Hospital / Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: The current conformity index (CI) formula is distorted for radiotherapy plans with multiple, non-enclosing targets. We redefined the volume of reference isodose (VTV) parameter in the CI form...
Authors: Rodrigo T Massera, Sofia Giaccone Thomaz, Alessandra Tomal, Giovanna Tramontin
Affiliation: Universidade Estadual de Campinas. Instituto de Física Gleb Wataghin, Department of Imaging & Pathology, unit of Medical Physics & Quality Assessment, KU Leuven
Abstract Preview: Purpose: Monte Carlo simulations are increasingly used in breast dosimetry for their precision in estimating difficult-to-measure quantities, such as glandular dose. With ionizing radiation in breast ...
Authors: Manju Liu, Weiwei Sang, Yanyan Shi, Zhenyu Yang, Fang-Fang Yin, Chulong Zhang, Lihua Zhang, Rihui Zhang
Affiliation: Jiahui International Hospital, Jiahui International Hospital, Radiation Oncology, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: This study aims to transform cone-beam computed tomography (CBCT) images acquired from deep inspiration breath-hold (DIBH) breast cancer patients into high-fidelity synthetic CT (sCT) images....
Authors: Beatriz Allyne Dia Carandang, Chitho P Feliciano, Teresa Sy-Ortin
Affiliation: Department of Physical Sciences and Mathematics, University of the Philippines Manila, Health Physics Research Section, Atomic Research Division, Department of Science and Technology-Philippine Nuclear Research Institute (DOST-PNRI), Graduate School, University of Santo Tomas
Abstract Preview: Purpose: To investigate the X-ray radiation-induced bystander effect (RIBE), where unirradiated cells mimic the responses of directly irradiated cells, in MCF-7 breast cancer cells in vitro to underst...
Authors: James Ward, Anzi Zhao
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: This study investigates the impact of tissue-equivalent attenuator materials, the region of interest (ROI) size, and the orientation of the attenuator positioning on the measured signal-to-no...
Authors: Liang Cui, Xingyu Lu, Hang Shang, LingHong Zhou
Affiliation: Southern Medical University
Abstract Preview: Purpose: This study examines how varying dose rates of radiotherapy impact normal tissues outside the target area and analyzes the protective effects and regulatory mechanisms of ultra-high dose rate ...
Authors: Keyi Bian, Marco Caballo, Wenxiu Guo, Haijie Li, Jiao Li, Aidi Liu, Yue Ma, Ioannis Sechopoulos, Yafei Wang, Yaopan Wu, Zhaoxiang Ye, Yuwei Zhang, Yueqiang Zhu, Daan van den Oever
Affiliation: Radboud University Medical Center, Tianjin Medical University Cancer Institute & Hospital, Sun Yat-Sen University Cancer Center
Abstract Preview: Purpose: To develop and validate a nomogram integrating intra- and peritumoral radiomics of contrast-enhanced cone-beam breast CT (CE-CBBCT) and clinicopathologic features for predicting fluorescence ...
Authors: Deng-Yuan Chang, Matthew L. Scarpelli
Affiliation: Purdue University
Abstract Preview: Purpose: Tumor-associated macrophages (TAMs) can be assessed by Ferumoxytol-MRI in breast cancer because they are negatively correlated with the prognosis of patient outcome. However, some studies hav...
Authors: Ramesh Boggula, Yash Somnay, Hualin Zhang
Affiliation: Radiation Oncology, Keck School of Medicine of USC, Wayne State University
Abstract Preview: Purpose: Spatially fractionated radiation therapy (SFRT) allows delivery of therapeutic doses to bulky tumors otherwise limited by dose-volume effects that threaten organ-at-risk tolerances. For negle...
Authors: Marian Axente, Mandeep Kaur
Affiliation: Emory University
Abstract Preview: Purpose: To validate a low-cost optical imaging system for respiratory monitoring by comparing its accuracy and feasibility against the clinical gold standard in human subjects.
Methods: Following ...
Authors: Anthony R Bardwell, Dong Won Kim, Faith S Kim, Isaac Y Kim, Juying Zhang
Affiliation: Kaiser Permanente
Abstract Preview: Purpose: When a patient develops a significant skin reaction at some point during postmastectomy radiotherapy, a clinical decision is often made to discontinue the planned daily use of bolus. The aim ...
Authors: Thomas Furno, Arjen Winkel, Ramtin Zakikhani
Affiliation: Genesis Care USA, QLRAD, SMH
Abstract Preview: Purpose: To quantify the dosimetric impact of the newly introduced “Inframammary Fold (IMF) Breast WedgeTM ” device by QLRAD inc. in the region of the inframammary fold during breast radiotherapy.
...
Authors: Les Butler, Joyoni Dey, Conner B Dooley, Victoria L Fontenot, Kyungmin Ham, Hunter Cole Meyer
Affiliation: Louisiana State University, Center for Advanced Microstructures and Devices, Linfield University
Abstract Preview: Purpose: X-ray interferometry is an emerging imaging modality with a wide variety of potential clinical applications, including lung and breast imaging. Small inaccuracies in grating position lead to ...
Authors: Klaus Bacher, Louise D'hondt, Jeff Rutten, Gwenny Verfaillie
Affiliation: Ghent University
Abstract Preview: Purpose: Manual organ segmentation is a very time-consuming but necessary process in personalized dosimetry. Automatic segmentation tools may alleviate this task. In this study the impact of automatic...