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Results for "computed tomography": 108 found

3D Printing Assisted Collimator Design for Fan Beam-Based X-Ray Fluorescence Tomographic Imaging

Authors: Brett Bocian, Nesrin Dogan, John C. Ford, Alan Pollack, Ryder Marshall Schmidt, Junwei Shi, Jorge D Vega

Affiliation: University of Miami, University of Miami Sylvester Comprehensive Cancer Center

Abstract Preview: Purpose: X-ray fluorescence computed tomography (XFCT) is an emerging molecular imaging modality gaining attention in cancer theranostics with high-Z metal nanoparticles (MNPs). While XFCT has been de...

4D CBCT Reconstruction Using Denoising Diffusion Implicit Models

Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Bohong Huang, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Four-dimensional cone-beam computed tomography (4D-CBCT) is critical in image-guided radiotherapy (IGRT) for visualizing tumor motion. However, sparse projection sampling often introduces sev...

A Comparative Study of Hypersight and Truebeam Cone Beam Computed Tomography Image Quality

Authors: Sorour Hosseini, YuHuei Jessica Huang, Thomas Boyd Martin, Geoffrey S. Nelson, Nicholas Pierre Nelson, Hui Zhao

Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah

Abstract Preview: Purpose: To evaluate image quality—including noise, contrast-to-noise ratio (CNR), uniformity, and low-contrast visibility (LCV)—on the HyperSight and TrueBeam cone-beam computed tomography (CBCT) pla...

A Foundational Model for Medical Imaging Modality Translation in Head and Neck Radiotherapy

Authors: Jie Deng, Yunxiang Li, Xiao Liang, Weiguo Lu, Jiacheng Xie, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Recently, foundational models trained on large datasets have shown remarkable performance across various tasks. Developing a foundational model for medical image modality translation in head-...

Advancing Magnetic Resonance Imaging (MRI) Safety Clearance: Utilizing Dual-Energy CT (DECT) Material Decomposition for Foreign Object Assessment

Authors: Anzi Zhao

Affiliation: Northwestern Medicine

Abstract Preview: Purpose: This study investigates the utility of Dual-Energy Computed Tomography (DECT) material decomposition in resolving Magnetic Resonance Imaging (MRI) safety concerns for patients with unidentifi...

Afterloader Integrated Electromagnetic Tracking Can be Used to Accurately Define and Assess the Dwell Position Model of Venezia™ Gynaecological Brachytherapy Applicators

Authors: Ioannis Androulakis, Jérémy Godart, Mischa Hoogeman, Inger-Karine K. Kolkman-Deurloo, Remi A. Nout, Robin Straathof, Henrike Westerveld, Myra van Laar

Affiliation: Department of BioMechanical Engineering, Delft University of Technology, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam

Abstract Preview: Purpose:
In brachytherapy for gynaecological cancers using intracavitary applicators, implant reconstruction is commonly performed using applicator libraries. These libraries contain applicator geo...

An Adaptive Radiotherapy Strategy Study Based on Segmented Synthesis and Deformational Registration

Authors: Jie Hu, Zhengdong Jiang, Nan Li, Tie Lv, Yuqing Xia, Shouping Xu, Gaolong Zhang, Wei Zhao, Changyou Zhong

Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Radiotherapy Department of Meizhou People’s Hospital (Huangtang Hospital), UT Health San Antonio, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, Peopleʼs Republic of China, Department of Radiation Oncology

Abstract Preview: Purpose: Patients usually undergo cone-beam computed tomography (CBCT) scans which are used for patient set-up before radiotherapy. However, the low image quality of CBCT hinders its use in adaptive r...

Assessing the Feasibility of LD-V1 Film for Annual Kilovoltage Imaging Dose Measurements

Authors: Maria F. Chan, Seng Boh Gary Lim, Shih-Chi Lin, Dustin W. Lynch, Usman Mahmood, Jeonghoon Park

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: To explore the feasibility of using GafChromic LD-V1 film for annual imaging dose assessment across kV radiography, fluoroscopy, and cone beam computed tomography (CBCT) imaging protocols, as...

Assessment of the Radiological Features of 3D-Printed Polylactic Acid Composites for Creating Personalized Dosimetric Phantoms

Authors: Ashish Binjola, Raj Kishore Bisht, Natanasabapathi Gopishankar, Pratik Kumar, Daya Nand Kishore Sharma, Sukhvir Kishore Singh, Subramani Vellaiyan

Affiliation: Medical Physics Unit, All India Institute of Medical Sciences, All India Institute of Medical Sciences, Department of Radiological Safety, Institute of Nuclear Medicine and Allied Sciences, Department of Radiation Oncology, All India Institute of Medical Sciences

Abstract Preview: Purpose: Additive manufacturing is increasingly being explored to create dosimetry phantoms. Commercial anthropomorphic phantoms represent an average patient and lack anatomical variations due to obes...

Automated Diagnosis of Pancreatic Cancer Using Both Radiomics and 3D-Convolutional Neural Network

Authors: Beth Bradshaw Ghavidel, Benyamin Khajetash, Yang Lei, Meysam Tavakoli

Affiliation: Icahn School of Medicine at Mount Sinai, Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Emory University, Department of Radiation Oncology, Emory University

Abstract Preview: Purpose: Pancreatic cancer is among the most aggressive types of cancer, with a five-year survival rate of approximately 10%. Recent studies show that radiomics and deep learning (DL)-based methods ar...

BEST IN PHYSICS IMAGING: Volumetric Sampling Properties of Longitudinal Multiple X-Ray-Source Array Computed Tomography (MXA-CT)

Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski, Huanyi Zhou

Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation

Abstract Preview: Purpose: A new CT configuration utilizing a multiple X-ray-source array (MXA) is under development to mitigate cone-beam (CB) artifacts in single-rotation wide coverage imaging. We investigate the sam...

Backscattering of Compton Cameras: A Monte Carlo Simulation Approach

Authors: Jorge Naoki Dominguez Kondo, Qihui Lyu

Affiliation: University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose:
Targeted alpha therapy (TAT) has emerged as a highly potent therapeutic method in oncology, but its development is limited by the lack of imaging methods to quantify its dosimetry. Convent...

Benefits on Respiratory Gating Delivery of Lung SBRT

Authors: Andrew Huang, Jonathan Huang, Andrew S Kennedy, Ellie Grace Kong, Ajay Zheng

Affiliation: New York Proton Center, Centennial Medical Center, Executive Medical Physics Associates, Sarah Cannon Cancer Institute, Belmont University

Abstract Preview: Purpose:
Lung stereotactic body radiotherapy (SBRT) is the standard of care for early-stage lung cancer. Respiratory phase gating can be applied to mitigate motion-induced effects. The purpose of t...

Breathing New Life into Pulmonary Imaging: Development and Clinical Validation of an X-Ray Interferometry System

Authors: Rachael Blair, Les Butler, Lillian Dickson, Kyungmin Ham, Charles Hartman, Kenneth (Kip) Matthews, Corinne Vanya

Affiliation: Louisiana State University, University of Minnesota, Refined Imaging LLC, Center for Advanced Microstructures and Devices

Abstract Preview: Purpose:
To develop and evaluate an x-ray interferometry system (XIS) for low-dose, high-sensitivity diagnostic imaging of lung diseases such as chronic obstructive pulmonary disease (COPD), asthma...

CBCT Dose Measurement for Common Protocols on Elekta Versahd and Varian Truebeam

Authors: Yingxuan Chen, Jun Li, Alexis N. Webb

Affiliation: Thomas Jefferson University

Abstract Preview: Purpose: Cone-beam computed-tomography (CBCT) is widely used for image-guided therapy. Cumulative dose from repeated CBCT might be a concern. This study aims to measure and compare the CBCT dose for c...

Can Regional Radiomic Features from Pre-Treatment Computed Tomography Serve As Biomarkers for Predicting Radiation Pneumonitis?

Authors: David J. Carlson, Ming Chao, Tian Liu, Yong Hum Na, Kenneth E Rosenzweig, Robert Samstein, Lewis Tomalin

Affiliation: Icahn School of Medicine at Mount Sinai, Yale University School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: To investigate the potential of regional radiomic features extracted from five lung sub-lobes on pre-treatment CT as biomarkers for predicting radiation pneumonitis (RP) using machine learnin...

Comparative Study between Sparse Primary Sampling Grid Scatter Correction and Low-Count Monte Carlo-Based Scatter Reduction with 3-D Richardson-Lucy Denoising

Authors: Alan Rui Li, Qihui Lyu, Dan Ruan, Ke Sheng

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose:
The Sparse Primary Sampling (SPS) grid was shown in a previous computational study to improve image quality by correcting scatter-induced effects and artifacts in Cone-beam Computed Tomogr...

Comparison of Computed Tomography Scanner Protocols Using an in-House Automated Method across Machines at a Single Institution

Authors: Matthew R. Hoerner, Maryam Naseri, Mena Shenouda

Affiliation: Yale University School of Medicine, Yale University

Abstract Preview: Purpose: To evaluate acquisition parameters of computed tomography (CT) scanner protocols across different machines to provide patients and clinicians consistent care and image quality, respectively.<...

Comparison of Frame-Based and Frameless Gamma Knife Coordinate Spaces for Treatment of Trigeminal Neuralgia

Authors: Tatiana Bejarano, Omer Gal, Alonso N. Gutierrez, Matthew D. Hall, Rupesh Kotecha, Yongsook C. Lee, Michael W. McDermott, Minesh P. Mehta, Robert H. Press, Carlos M. Rivera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek

Affiliation: Miami Cancer Institute, Baptist Health South Florida

Abstract Preview: Purpose:
Gamma Knife (GK) cone beam computed tomography-based stereotactic reference (CBCTRef) combined with pre-planning MRI, provides a flexible alternative to the historical frame-based localiza...

Comparison of Optimized Magnetic Resonance Sequences in the Treatment Planning of Surface Brachytherapy

Authors: Ivan M. Buzurovic, Phillip M. Devlin, Evangelia Kaza, Michael John Lavelle

Affiliation: Department of Radiation Oncology, Dana-Farber/Brigham and Women’s Cancer Center, Harvard Medical School, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology

Abstract Preview: Purpose: Recent work in surface brachytherapy (SBT) has demonstrated the feasibility of using magnetic resonance (MR)-guidance in place of Computer Tomography (CT) in SBT planning. The purpose of this...

Comparison of Radiomic Feature Normalizations, Feature Selection, and Modeling with Different Datasets

Authors: Eric N Carver, Julia Marks

Affiliation: Brown University

Abstract Preview: Purpose: The clinical applicability of radiomic features is hindered by challenges in stability and reproducibility. To address this, researchers are establishing image and feature standardizations an...

Comparison of Respiratory Motion between 4D-MR and 4D-CT in Compression Belt Patients

Authors: Morgan Aire, Krystal M. Kirby, Olivia Magneson, David E. Solis, Hamlet Spears

Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center

Abstract Preview: Purpose: This study evaluates the range of motion of abdominal organs using 4D stack-of-stars magnetic resonance (MR) imaging and 4D computed tomography (CT), the current clinical standard. Accurate o...

Comparison of Ultra-High Resolution and Standard CT Imaging Modes for Small Vessel Visualization in Coronary CTA Using Photon Counting CT

Authors: Afrouz Ataei, Victor Moy, Mark P. Supanich

Affiliation: Rush University

Abstract Preview: Purpose: This study evaluates the impact of ultra-high resolution (UHR) mode on the visualization of small vessels in coronary computed tomography angiography (CTA) using a photon-counting CT scanner....

Comprehensive Commissioning of an O-Ring-Shaped Image-Guided Radiotherapy System with a Gimbal-Mounted Linear Accelerator

Authors: Tetsuo Fukuda, Hideaki Hirashima, Kohei Kawata, Yukako Kishigami, Takashi Mizowaki, Mitsuhiro Nakamura, Yohei Sawada, Maika Urago

Affiliation: Kyoto University, kyotoUnivercity, Hitachi high-tech, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University

Abstract Preview: Purpose: To present the comprehensive commissioning results of the O-ring shaped linac, OXRAY.
Materials and Methods: OXRAY enables a novel three-dimensional unicursal noncoplanar irradiation metho...

Comprehensive Evaluation of High-Performance Cone-Beam Computed Tomography on C-Arm and Ring-Gantry Linacs for Adaptive Radiation Therapy

Authors: Laura I. Cervino, Karen Episcopia, Hsiang-Chi Kuo, Sangkyu Lee, Seng Boh Gary Lim, Shih-Chi Lin, Grace Tang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: This study evaluated the performance of the HyperSight Cone-Beam Computed Tomography (CBCT) system on a TrueBeam C-arm LINAC (TB) and two Ethos ring-gantry LINACs (ES) for adaptive radiation ...

Computed Tomography

Authors: Frank F. Dong, Frank F. Dong

Affiliation: UT MD Anderson Cancer Center

Abstract Preview: N/A...

Computed Tomography Organ Dose Library Derived from Newly Developed Newborn-Infant-Toddler Computational Phantoms

Authors: Jared Baggett, Wesley E. Bolch, Lukas M. Carter, Robert Joseph Dawson, Laura Dinwiddie, Adam Leon Kesner, Cameron B. Kofler, Juan Camilo Ocampo Ramos, Yitian Wang, Stefan Wehmeier

Affiliation: University of Chicago, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, University of Florida, MD Anderson

Abstract Preview: Purpose: To develop a slice-specific computed tomography (CT) organ dose library using Monte Carlo radiation transport simulations on a newly created set of newborn, infant, and toddler computational ...

Contrast-Free Enhancement of Coronary Artery Stenosis: Synthetic Ccta from Non-Contrast CT Using Diffusion Model

Authors: Abdusalam Abdukerim

Affiliation: Institute for Medical Imaging Technology, Ruijin Hospital

Abstract Preview: Purpose:
Coronary computed tomography angiography (CCTA) is the gold-standard non-invasive test for coronary artery disease (CAD), but iodine contrast agents (ICA) pose limitations in specific popu...

Dedicated Cone-Beam Breast CT: Investigation on the Effect of Lesion Type on Detectability Index Using Cascaded Systems Analysis.

Authors: Jing-Tzyh Alan Chiang, Andrew Karellas, Thomas C Larsen, Hsin Wu Tseng, Srinivasan Vedantham

Affiliation: Department of Biomedical Engineering, The University of Arizona, Department of Medical Imaging, The University of Arizona

Abstract Preview: Purpose: To investigate the performance of dedicated breast computed tomography (BCT) for the the tasks of detection of soft tissue lesions and microcalcifications using cascaded systems analysis. The...

Deep Autoencoder for Ring Artifact Denoising in Photon-Counting CT

Authors: Magdalena Bazalova-Carter, James Day, Xinchen Deng

Affiliation: University of Victoria

Abstract Preview: Purpose:
Ring artifacts in Photon-Counting Computed Tomography (PCCT) images can degrade image quality. this study aims to suppress ring artifacts with a novel autoencoder-based framework that leve...

Deep Learning-Based Fast CBCT Imaging with Orthogonal X-Ray Projections for Gynecological Cancer Radiotherapy

Authors: Beth Bradshaw Ghavidel, Chih-Wei Chang, Yuan Gao, Priyanka Kapoor, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Jill Remick, Justin R. Roper, Zhen Tian, Xiaofeng Yang

Affiliation: Whinship Cancer Institute, Emory University, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Current cone-beam computed tomography (CBCT) typically requires no less than 200 degrees of angular projections, which prolongs scanning time and increases radiation exposure. To address thes...

Deep Learning-Based Prompt Gamma Imaging for Proton Range Verification Using Patient Data Simulation

Authors: Mostafa Cham, Matthias K Gobbert, Zhuoran Jiang, Sina Mossahebi, Ruth Obe, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma

Affiliation: University of Maryland School of Medicine, UMBC, University of Maryland Baltimore County, University of Maryland, Baltimore County, Stanford University, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc, Department of Infomation Systems, UMBC

Abstract Preview: Purpose: Compton camera (CC)-based prompt gamma imaging (PGI) offers real-time proton range verification. However, its limited-angle measurements cause severe distortions in PGI, affecting its clinica...

Design of Filtimator (Filter + Collimator) for CBCT of Pediatric Cancer Patients Receiving Proton Therapy

Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens

Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI

Abstract Preview: Purpose:
Cone-beam computed tomography (CBCT) doses shall be limited for pediatric patients in clinical settings. Device called Filtimator (filter+collimator) was custom designed to reduce setup CB...

Development of Sphere Phantoms for Quantitative Evaluation of Computed Tomography Systems Resolution

Authors: Hyo-Min Cho, Changwoo Lee

Affiliation: Korea Research Institute of Standards and Science

Abstract Preview: Purpose: We develop sphere phantoms to assess spatial resolution of computed tomography (CT) systems and validate its usability using table-top X-ray experiment systems.
Methods: We manufactured sp...

Diffusion Model-Based Motion Correction in Portable Computed Tomography for Brain: Human Observer Study

Authors: Rajiv Gupta, Rehab Naeem Khalid, Min Lang, Michael H Lev, Quirin Strotzer, Matthew Tivnan, Maryam Vejdani-Jahromi, Dufan Wu, Siyeop Yoon, Chen Zhennong

Affiliation: Massachusetts General Hospital

Abstract Preview: Purpose: Patient motion is a major source of artifacts in portable brain CT due to the slow scanning speed. A diffusion model was developed to reduce these motion artifacts. This work aims to assess t...

Dose Mapping of Radioactive Gold Nanoparticles Using Three-Dimensional Dosimetry

Authors: Ana Laura Burin, Maysa Müller Ferreira Gesserame, David Alexander Urbina Leal, Ilca Marli Moitinho Amaral Medeiros, Silas Leonel Pereira Miranda, Thuany Corrêa Nogueira, Maria da Penha Alburquerque Potiens, Pedro Henrique Ricardo, Maria Eduarda Zaganin Rigo, Orlando Rodrigues, Priscila Santos Rodrigues, Wilmmer Alexander Arcos Rosero, Maria Elisa Chuery Martins Rostelato, Sabrina Spigaroli Sgrignoli, Ana Catarina Koka de Souza Silva, Cristhian Ferreira Talacimon, Paulo Victor dos Santos Tavares, Lara El Hajj Teodoro, Carlos Alberto Zeituni, José Neres de Almeida

Affiliation: IPEN - USP

Abstract Preview: Purpose: Perform three-dimensional dosimetry of radioactive gold nanoparticles (¹⁹⁸AuNPs) using Fricke xylenol gel (FXG), aiming to determine the dose distribution and evaluate the method's effectiven...

Dosimetric Evaluation of Radiation Treatment Planning Algorithms in IMRT and VMAT Techniques: Analysis with Central and Peripheral Lung Tumors

Authors: Sumanta Manna, Atul Mishra, Surendra Prasad Mishra, Kailash Kumar Mittal, Anoop Kumar Srivastava, Neha Yadav

Affiliation: Department of Radiation Oncology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Department of radiation Oncology, Apollomedics Super Speciality Hospitals, Department of Radiation Oncology, Uttar Pradesh University of Medical Sciences, Department of Radiation Oncology, Kalyan Singh Super Specialty Cancer Institute

Abstract Preview: Purpose: This study aimed to assess the dosimetric performance of Volumetric Modulated Arc Therapy (VMAT), step-and-shoot Intensity-Modulated Radiation Therapy (ss-IMRT), and dynamic Intensity-Modulat...

Dual Energy Cone Beam Computed Tomography for Artifact Reduction and Enhanced Image Quality Using Existing Hardware in Radiation Therapy

Authors: Michael J. Choi, Vindu Wathsala Kathriarachchi, Christopher L. Nelson, Andrew P. Soderstrom, Yawei Zhang

Affiliation: The University of Texas MD Anderson Cancer Center, MD Anderson, UF Health Proton Therapy Institute

Abstract Preview: Purpose: Cone Beam Computed Tomography (CBCT) is widely used in image-guided radiation therapy for patient positioning. While kV photons offer high image contrast, they are prone to artifacts caused b...

Dynamic X-Ray Acoustic Computed Tomography (XACT)

Authors: Leshan Sun, Liangzhong Xiang, Yifei Xu, Yuchen Yan

Affiliation: University of California, Irvine

Abstract Preview: Purpose: X-ray Acoustic Computed Tomography (XACT) is a transformative innovation in medical imaging, overcoming the limitations of conventional X-ray techniques. It introduces new possibilities in cl...

Emulating Human Perception of Low-Dose CT Image Quality Via Deep Generative Models

Authors: Jongduk Baek, Jooho Lee, Adam S. Wang

Affiliation: Stanford University, Yonsei University

Abstract Preview: Purpose: Optimizing the balance between radiation dose and image quality in computed tomography (CT) is important for minimizing patient X-ray exposure while maintaining diagnostic accuracy. While rad...

Enhance Four-Dimension Cone-Beam Computed Tomography (4D-CBCT) from Sparse Views Using a Novel Deep Learning Model

Authors: Lei Ren, Jie Zhang

Affiliation: University of Maryland School of Medicine

Abstract Preview: Purpose: 4D-CBCT is valuable for imaging anatomy affected by respiratory motions to guide radiotherapy delivery. However, 4D-CBCT often has undersampled projections acquired in each respiratory phase ...

Enhanced Lung Function Assessment through Machine Learning Analysis of 4DCT Subregional Respiratory Dynamics

Authors: Jing Cai, Zhi Chen, Hong Ge, Yu-Hua Huang, Bing Li, Zihan Li, Ge Ren

Affiliation: Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Department of Radiation Oncology, The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital

Abstract Preview: Purpose: Algorithms based on subregional respiratory dynamics (SRD) capture spatiotemporal heterogeneity in the ventilation process, though rely on empirical modelings to map surrogate ventilation. Gi...

Enhancing Radiation Oncology Imaging with a Novel Variational Model Decomposition, Radon Transformation, and Kohonen Self-Organizing Map Denoising Framework

Authors: Hassan Bagher-Ebadian, Justine M. Cunningham, Anthony J. Doemer, Mohammad M. Ghassemi, Joshua P. Kim, Benjamin Movsas, Kundan S Thind

Affiliation: Michigan State University, Henry Ford Health

Abstract Preview: Purpose: Reduction of noise in medical images critically enables improved accuracy in delineating tumors and organs at risk, leading to more precise treatment planning and safer image-guided radiation...

Evaluating PET-Based Metrics to Identify Patients with Liver Metastases for Biology-Guided Radiotherapy

Authors: Girish Bal, Ke Colin Huang, Christopher F. Njeh, Oluwaseyi Oderinde, Yong Yue

Affiliation: Purdue University, RefleXion Medical, Indiana University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose: Biology-guided radiotherapy (BgRT) uses real-time positron emission tomography (PET) signals to precisely direct radiotherapy beamlets. The success of BgRT planning and delivery relies on PET...

Evaluating the Impact of Contour Variability on the Effectiveness of Deep Learning Features in Head and Neck Imaging

Authors: Hania A. Al-Hallaq, Xuxin Chen, Anees H. Dhabaan, Elahheh (Ella) Salari, Xiaofeng Yang

Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose:
Radiomics image analysis could lead to the development of predictive signatures and personalized radiotherapy treatments. However, variations in delineation are known to affect hand-crafte...

Evaluation of Thoracic Direct Dose Calculation Using Truebeam Linac with Hypersight Imaging CBCT Solution

Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Alex T. Price, Sagar Regmi, Atefeh Rezaei, Runyon C. Woods

Affiliation: University Hospitals Seidman Cancer Center

Abstract Preview: Purpose: To investigate the feasibility and accuracy of using a Hounsfield Unit(HU) calibrated cone-beam computed tomography(CBCT) for direct dose calculation in thoracic treatment settings. In combin...

Evaluation of Treatment Delivery Efficiency and Workflow Optimization in Prostate Stereotactic Body Radiation Therapy: A Comparative Study of C-Arm and O-Ring Linear Accelerators

Authors: Yijian Cao, Jenghwa Chang, Lyu Huang

Affiliation: Northwell, Hofstra University Medical Physics Program

Abstract Preview: Purpose: This study evaluates the treatment delivery efficiency and workflow of two advanced linear accelerator systems—Varian’s TrueBeam (C-arm) and Halcyon (O-ring)—for prostate Stereotactic Body Ra...

Evaluation of the Reflexion X1 As a Standalone PET/CT Simulator for Treatment Planning and Treatment Adaptation

Authors: Chunhui Han, An Liu, William T. Watkins, Qiuyun Xu

Affiliation: Department of Radiation Oncology, City of Hope National Medical Center

Abstract Preview: Purpose: To evaluate the RefleXion X1 imaging system as a standalone positron emission tomography and computed tomography (PET/CT) simulator for radiotherapy treatment planning and adaptive re-plannin...

Feasibility of 3D Printing for Fabricating Anthropomorphic Kidney Phantoms

Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Wagner Henrique Marques, Raphael Morata, Victor H.F Oliveira

Affiliation: University of São Paulo (USP), Institute of Physics

Abstract Preview: Purpose: This study investigates the feasibility of 3D printing materials in creating anthropomorphic kidney phantoms that accurately simulate the radiological properties of human tissues, for applica...

Feasibility of Real-Time Monitoring in Tumor Treating Fields Therapy Using Electrical Impedance Tomography: Analysis of Current Injection and Measurement Patterns

Authors: Sung Hwan Ahn, Yongha Gi, Jinju Heo, Jinyoung Hong, Yunhui Jo, Yousun KO, Hyeongjin Lim, Sang Yoon PARK, Myonggeun Yoon

Affiliation: Institute of Global Health Technology (IGHT), Korea University, Republic of Korea, Korea University, Samsung Medical Center

Abstract Preview: Purpose:
This study aims to evaluate the feasibility of real-time monitoring of conductivity changes induced by thermal variations during tumor treating fields (TTFields) therapy using Electrical I...

First in-Vivo Application of a Novel Precision Small Animal Irradiation Platform with Proton IMPT Delivery and Advanced on-Board Image-Guidance

Authors: Niels Bassler, Jonathan Bortfeldt, Davide Boscaini, Francesco Evangelista, Guyue Hu, Ze Huang, Margarita Kozak, Julie Lascaud, Giulio Lovatti, Eero Lönnqvist, Jasper Nijkamp, Munetaka Nitta, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Babak Sharifi, Brita Singers Sørensen, Peter Thirolf

Affiliation: Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Ludwig-Maximilians Universität, Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital

Abstract Preview: Purpose: To perform the first in vivo application of a novel small animal radiation research platform combining on-board image-guidance with multi-field intensity modulated spot scanning delivery [1] ...

Foundation Model Guidance for CBCT-CT Image Registration in Radiotherapy

Authors: Hacene Azizi, Abderaouf Behouch, Nabil Maalej, Aamir Raja, Mohamed Lamine Seghier

Affiliation: Khalifa University Biomedical Engineering & Biotechnology, Laboratory of dosing, analysis and characterization in high resolution, Ferhat Abbas Setif 1 University, Khalifa University Physics Department, Khalifa University

Abstract Preview: Purpose:
To ensure accurate alignment of cone-beam computed tomography (CBCT) and computed tomography (CT) images for image-guided radiotherapy, this study evaluates a foundation model guidance fra...

Four-Dimensional Computed Tomography Based on 16cm-Long Detectors Vs 4cm-Long Detectors: Dose Validation

Authors: Qianyi Xu, Inhwan Yeo

Affiliation: INOVA Schar Cancer Institute, Thomas Jefferson University

Abstract Preview: Purpose:
Four-dimensional computed tomography(4DCT) is prone to a geometrical error when respiration changes upon patient shift. 4DCT with a longer-length detector(16cm), uninvolving the shift, has...

Four-Dimensional on-Beam Computed Tomography Reconstruction from Projection Image Differences Representing Motion Change

Authors: Kwang-Ho Cheong, Seungryong Cho, Joonil Hwang, Jae Won Jung, Hoyeon Lee, Raymond Hyunwoo Moon, Inhwan Yeo, Jihyung Yoon

Affiliation: East Carolina University, INOVA Schar Cancer Institute, University of Hong Kong, Hanllym University, KAIST, University of Rochester

Abstract Preview: Purpose: Monitoring a target and neighboring organs during beam delivery is crucial for successful radiotherapy (RT). Conventional transit imaging methods lack volumetric reconstruction capabilities, ...

Fully Automated Zero-Shot Organ Segmentation in Male Pelvic MR Images for MR-Guided Radiation Therapy

Authors: Jihun Kim, Jin Sung Kim, Jun Won Kim, Yong Tae Kim, Chanwoong Lee, Jihyn Pyo, Young Hun Yoon

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine

Abstract Preview: Purpose: Although segmentation foundation models have recently demonstrated promising zero-shot performance on natural images, its clinical application to magnetic resonance (MR) images still requires...

Generalized Ontological Framework for CT Data Profiling and Characterization

Authors: Njood Alsaihati, Ehsan Samei, Justin B. Solomon

Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Inconsistent imaging procedure naming across and within institutions challenges clinical decision-making, quality assessment, and data analysis in radiology. For example, The American College...

Generating Synthetic Positron Emission Tomography from Computed Tomography Using Lightweight Diffusion Model for Head and Neck Cancer

Authors: Rashmi Bhaskara, Shravan Bhavsar, Ananth Grama, Oluwaseyi Oderinde, Shourya Verma

Affiliation: Purdue University

Abstract Preview: Generating Synthetic Positron Emission Tomography from Computed Tomography using Lightweight Diffusion Model for Head and Neck Cancer
Purpose: To generate synthetic PET tumor avidity segments direc...

Glandular Dose Map in Voxelized Phantoms across Advanced Breast Imaging Modalities Obtained from Monte Carlo Simulations

Authors: Rodrigo T Massera, Sofia Giaccone Thomaz, Alessandra Tomal, Giovanna Tramontin

Affiliation: Universidade Estadual de Campinas. Instituto de Física Gleb Wataghin, Department of Imaging & Pathology, unit of Medical Physics & Quality Assessment, KU Leuven

Abstract Preview: Purpose: Monte Carlo simulations are increasingly used in breast dosimetry for their precision in estimating difficult-to-measure quantities, such as glandular dose. With ionizing radiation in breast ...

High-Fidelity Synthetic CT Generation from CBCT for Dibh Breast Cancer Patients Using Shortest Path Regularization

Authors: Manju Liu, Weiwei Sang, Yanyan Shi, Zhenyu Yang, Fang-Fang Yin, Chulong Zhang, Lihua Zhang, Rihui Zhang

Affiliation: Jiahui International Hospital, Jiahui International Hospital, Radiation Oncology, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: This study aims to transform cone-beam computed tomography (CBCT) images acquired from deep inspiration breath-hold (DIBH) breast cancer patients into high-fidelity synthetic CT (sCT) images....

High-Quality Patchnet (HQ-PatchNet) for Synthetic CT Generation in Head & Neck Imaging

Authors: So Hyun Ahn, Chris Beltran, Byongsu Choi, Jeong Heon Kim, Jin Sung Kim, Bo Lu, Justin Chunjoo Park, Bongyong Song, Jun Tan

Affiliation: Mayo Clinic, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Ewha Medical Research Institute, Ewha Womans University College of Medicine, UC San Diego, Yonsei University College of Medicine

Abstract Preview: Purpose:
Cone-beam computed tomography (CBCT) is widely used in IGRT for patient positioning but suffers from low resolution and poor soft tissue contrast. Synthetic CT (sCT) generated from CBCT ad...

Hypersight® Offline Adaptive Workflow

Authors: Doris Dimitriadis/Dimitriadou, Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Noor Mail, Adam Olson, Tyler Wilhite

Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, UPMC

Abstract Preview: Purpose: The goal of the HyperSight® offline adaptive-workflow is to create a methodical approach to adaptive-radiotherapy (ART) that considers modifications in patient setup and anatomy. Through effi...

Iguard: A Fully Unsupervised Image-Guidance Anomaly Recognition and Detection Framework in CBCT-Guided Radiotherapy.

Authors: James M. Lamb, Dishane Chand Luximon, Jack Neylon, Rachel Petragallo, Moritz Ritter, Timothy Ritter

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, ETH Zurich, VCU Health System, Department of Radiation Oncology, University of Colorado

Abstract Preview: Purpose: Anomalies in cone beam computed tomography (CBCT) radiotherapy image guidance can signal treatment deviations. Repetitive review of setup image registrations by humans is inefficient, prone t...

Impact of Computed Tomography Noise Reference Levels in a Pediatric Hospital

Authors: Samuel L. Brady, Joseph G. Meier

Affiliation: Cincinnati Childrens Hospital Med Ctr

Abstract Preview: Purpose:
To establish noise reference levels for our pediatric hospital.
Methods:
Water equivalent diameter (Dw) and image noise was automatically measured by using a global noise algorithm i...

Inconsistencies in Methods for CMS Size-Adjusted Dose Measure

Authors: Alexander Alsalihi, Gary Y. Ge, Charles Mike Weaver, Jie Zhang

Affiliation: University of Kentucky

Abstract Preview: Purpose: The upcoming CMS regulation, titled “Excessive Radiation Dose or Inadequate Image Quality for Diagnostic Computed Tomography (CT) in Adults”, employs two measures, size-adjusted DLP (SAD) and...

Initial Phantom Studies Towards Implementation of Sequential Dual Energy CBCT on an Adaptive Radiotherapy Linac Platform

Authors: James M. Balter, Alexander Moncion, Ikechi S Ozoemelam

Affiliation: University of Michigan

Abstract Preview: Purpose: Sequential dual-energy cone beam computed tomography (DE-CBCT) integrated with an online adaptive platform could potentially improve soft tissue visualization for more accurate anatomical del...

Integrating SPECT and Compton Imaging for Multi-Energy Photon Reconstruction

Authors: Qihui Lyu, Javier Caravaca Rodriguez, Youngho Seo, Ke Sheng, Jingjie Yu

Affiliation: University of California San Francisco, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose:
Simultaneous broad-energy imaging is critical for many theragnostic applications, but the current Single-Photon Emission Computed Tomography (SPECT) can only image low energy photons with ...

Investigation of Low Iodine Concentration Detectability of Dual-Energy CT Imaging Using a Customized 3D Printed Phantom

Authors: Michalis Aristophanous, Laura I. Cervino, Maria F. Chan, Puneeth Iyengar, Hsiang-Chi Kuo, Nancy Y Lee, Xiang Li, Seng Boh Gary Lim, Usman Mahmood, Jean M. Moran, Jason Ocana

Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: To determine the limits of iodine concentration detection (LOD) and quantification (LOQ) in dual-energy computed tomography using a 3D printed phantom while considering different background, ...

Investigation of Metallic Artefact Reduction Capabilities of Hypersight Enabled Platforms

Authors: Harald Keller, Iymad Mansour, Jeff D. Winter

Affiliation: Princess Margaret Cancer Centre

Abstract Preview: Purpose: The growing number of adaptive therapy applications is motivating image segmentation and direct dose calculation on CBCT. The purpose of this investigation is to evaluate the recently release...

Lesion Detection in Contrast Enhanced Cone Beam Breast CT with a Photon Counting Detector: A Monte Carlo Study

Authors: Ahad Ollah Ezzati, Xiaoyu Hu, Xun Jia, Youfang Lai, Kai Yang, Yuncheng Zhong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University

Abstract Preview: Purpose: Contrast-enhanced breast cone-beam computed tomography (bCBCT) provides high-resolution, 3D imaging of breast tissues with improved differentiation between normal and abnormal tissues. Curren...

Long-Term Stability Assessment of an Imaging Ring System Using One Year of Monthly Quality Assurance Data

Authors: Awens Alphonse, Nebi Demez, Brian P. Laffey, Shyam Pokharel, Suresh Rana, Nishan Shrestha

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: The Imaging Ring is a mobile digital X-ray system capable of producing 2D planar X-rays, fluoroscopy, and 3D Cone-Beam Computed Tomography (CBCT) images. This study aimed to evaluate the long...

Mask Guided Diffusion Model for Metal Artifacts Reduction

Authors: Shusen Jing, Qihui Lyu, Dan Ruan, Ke Sheng, Qifan Xu

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose: Metallic implants can significantly distort sinograms, leading to severe artifacts in computed tomography (CT) reconstructions. Reconstructing CT images containing metal is fundamentally an i...

Monte Carlo Modeling of an Experimental X-Ray Fluorescence Computed Tomography (XFCT) System with a Pixelated CdTe Detector

Authors: Sang Hyun Cho, Sandun Y. Jayarathna, Neerajan Nepal

Affiliation: The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: To develop/validate a Monte Carlo (MC) model of an experimental benchtop x-ray fluorescence computed tomography (XFCT) system with a pixelated CdTe detector that can be used for MC simulation...

Multi-Mechanism CNN and Long Short-Term Memory Fusion Model for Improved CT-Based Thyroid Cancer Diagnosis

Authors: Yunfei Dong, Dongyang Guo, Jiongli Pan, Tao Peng, Caiyin Tang, Zhenyu Yang, Fang-Fang Yin, Lei Zhang, Tianyi Zhang, Yaogong Zhang

Affiliation: Duke Kunshan University, Department of Radiology, Taizhou People’s Hospital Affiliated to Nanjing Medical University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: This study aims to improve the accuracy of CT-based diagnosis of thyroid cancer by developing a hybrid model that integrates Convolutional Neural Networks (CNNs) with Long Short-Term Memory (...

Multi-Organ Segmentation of Pelvic Cone-Beam Computed Tomography (CBCT) with Transformer Models to Enhance Adaptive Radiotherapy for Prostate Cancer

Authors: Ming Chao, Thomas Chum, Tenzin Kunkyab, Yang Lei, Tian Liu, Richard G Stock, Hasan Wazir, Junyi Xia, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai

Abstract Preview: Purpose:
This study aims to develop effective strategies for multi-organ segmentation of pelvic cone-beam computed tomography (CBCT) images based on transformer models to facilitate adaptive radiat...

Multicentric Characterization of Organ-Based Tube Current Modulation in Thoracic and Abdominopelvic Computed Tomography: A Dosimetric and Image Quality Study

Authors: Corentin Desport, Dominique Iacchetti, Nicolas Kien, Ramiro Moreno, Melodie Munier, Séléna Pondard

Affiliation: Fibermetrix, Alara Expertise, Alara Group

Abstract Preview: Purpose: To evaluate the efficiency of organ-based tube current modulation (OBTCM) in thoracic and abdominopelvic Computed Tomography (CT) for different radiology departments and manufacturers. This s...

New Generation Photoacoustic Computed Tomography: From bench to bedside

Authors: Lei Li

Affiliation: Rice University

Abstract Preview: N/A...

Normal Tissue Dosimetry during Intra-Cavitary HDR Brachytherapy

Authors: Palanisamy Karunanithi, Karthikeyan Perumal, Siva Subramanian Vadivel

Affiliation: Dr. Kamakshi Memorial Hospital

Abstract Preview: Purpose:
Recent advancements in high dose-rate (HDR) brachytherapy include the image guidance, new applicators, and dose calculation algorithms. Brachytherapy has steep dose gradient, hence relativ...

Optimized Dosimetric Planning for Trigeminal Neuralgia Using Cyberknife S7 Precision TPS with Volo Optimizer

Authors: Amy Fitzpatrick, Kim Howard, Julius G. Ojwang, Neelu Soni

Affiliation: Mercy Hospital Springfield

Abstract Preview: Purpose: This study evaluates the dosimetric advantages and workflow improvements of the CyberKnife S7 Precision Treatment Planning System (TPS) with the VOLO optimizer for stereotactic radiosurgery (...

Optimizing Low-Dose Imaging Parameters for Dual-Energy Cone-Beam Computed Tomography in Image-Guided Radiation Therapy

Authors: Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Luke Layman, Jason Patrick Luce, Ha Nguyen, John C. Roeske

Affiliation: Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago

Abstract Preview: Purpose:
This study aims to optimize virtual monoenergetic (VM) images obtained from dual-energy (DE) cone-beam computer tomography (CBCT) protocols for Image-Guided Radiation Therapy (IGRT). The o...

Optimizing Vessel Wall Visualization Using a Novel Black-Blood CT Technique on Craniocervical CT Angiography

Authors: Xiaohu Li, Jianjun Shen, Guozhi Zhang, Sihua Zhong, Jingjie Zhou

Affiliation: United Imaging Healthcare

Abstract Preview: Purpose:
Visualization of carotid artery vessel wall on computed tomography angiography (CTA) imaging is challenging. This study aims to develop a novel post-processing technique, black-blood compu...

Patient-Specific Quality Assurance in SBRT Treatments Using 3D Polymer Gel Dosimetry

Authors: Esteban Arzaga-Barajas, Paola Jazmin Guadarrama Huerta, Jose Alejandro Jimenez, Guerda Massillon-JL, Maria Adela Poitevin-Chacón, Alejandro Rodriguez-Laguna

Affiliation: UNAM, Medica Sur

Abstract Preview: Purpose: To perform patient-specific quality assurance (PSQA) tests for four SBRT treatments of patients diagnosed with vertebral, ilium, pelvic lymph node and lung tumors.
Methods: MAGIC gel consi...

Personalized Anisotropic Margin Strategy for Cervical Cancer Online Adaptive Radiation Therapy

Authors: Jian Chen, Qiufen Guo, Aihua Li, Jing Liu, Junjie MA, Qian WU, Haonan Xiao, Peng Xie, Xiaohui Yan, Yong Yin, Zhe Zhang

Affiliation: Department of Radiation Oncology, Peking University Shenzhen Hospital, Department of Radiation Oncology and Physics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Obstetrics and Gynaecology, Liao Cheng People’s Hospital

Abstract Preview: Purpose: Online Adaptive radiation therapy (ART) has been an effective technique to manage patient’s inter-fractional anatomical changes and therefore reduces planning target volume (PTV). However, on...

Prediction of Vertebral Compression Fracture after Stereotactic Body Radiotherapy for Spinal Metastases Using Clinical, Radiomic and Dosiomic Features

Authors: Yukio Fujita, Syoma Ide, Kei Ito, Tomohiro Kajikawa, Satoshi Kito, Keiko Murofushi, Yujiro Nakajima, Yuhi Suda, Kentaro Taguchi, Naoki Tohyama, Fumiya Tsurumaki

Affiliation: Komazawa University Graduate School, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Department of Radiology, Kyoto Prefectural University of Medicine

Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) for spine metastases is more effective for pain relief and local control than conventional radiotherapy. However, it is associated with vertebral compres...

Predictive Quality of Differing Body Size Measurands for Radiation Risk Estimation in CT Imaging: A Virtual Trial Study

Authors: Njood Alsaihati, Francesco Ria, Ehsan Samei, Justin B. Solomon, Martina Talarico, Jered Wells

Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Radiation dose and associated risk in X-ray imaging is principally informed by patient size, further used in Computed Tomography (CT) to achieve prescribed image quality levels through tube c...

Quality Assurance of Four-Dimensional Computed Tomography (4DCT)

Authors: Teh Lin, Anna Oneil

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose: Four-dimensional computed tomography(4DCT) is often required to assess organ motions for thoracic and abdominal cancer patients. This study proposes a quality assurance (QA) procedure for two...

Quantifying Uncertainties in Radiation Risk and Performance-Based Clinical Risk Assessment in Clinical Computed Tomography

Authors: Em Harkness, Francesco Ria, Ehsan Samei

Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose:
A recently introduced mathematical method quantifies performance-based clinical risk to create a risk-to-risk assessment with radiation risk, rendering the so-called total risk. However, t...

Quantitative Analysis of Three Strategies for CTPA Scan Timing Optimization

Authors: Zahra Alyani Nezhad, Carrie Bartels, Rachel Bladorn, Sean D. Rose, Kelsey Schluter, Timothy P. Szczykutowicz

Affiliation: Departments of Radiology and Medical Physics, University Wisconsin-Madison, University of Wisconsin Madison, University of Wisconsin-Madison, University of Texas at Houston Medical School, University of Wisonsin-Madison

Abstract Preview: Purpose: Pulmonary embolism is a life-threatening condition, and computed tomography pulmonary angiography (CTPA) is the gold standard for diagnosis. Inadequate contrast enhancement often leads to a h...

Quantitative Fluorescence Molecular Tomography Guide Radiation Therapy

Authors: Jiahao Chen, Yunwen Huang, Yidong Yang, Shanshan Zhang, Ning Zhao, Cheng Zheng

Affiliation: Department of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China

Abstract Preview: Purpose: To develop a molecular image-guided radiotherapy technique for accurate and effective radiation treatment using quantitative fluorescence molecular tomography (FMT).
Methods: X-ray cone be...

Rapid CBCT Imaging with Ultra-Sparse X-Ray Projections for Head & Neck Cancer Radiotherapy

Authors: Hania A. Al-Hallaq, Chih-Wei Chang, Anees H. Dhabaan, Yuan Gao, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Keyur Shah, Sibo Tian, Zhen Tian, Xiaofeng Yang, David Yu, Jun Zhou

Affiliation: Emory University, Whinship Cancer Institute, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Traditional cone-beam computed tomography (CBCT) often requires multiple angular projections, increasing radiation exposure and extending scanning times, which may lead to heightened patient ...

Ratoguide: Evaluation of AI-Driven Fully Automated Treatment Planning Support System for Lung SBRT

Authors: Keiichi Jingu, Noriyuki Kadoya, Takafumi Komiyama, Takeru Nakajima, Hikaru Nemoto, Hiroshi Onishi, Masahide Saito, Ryota Tozuka

Affiliation: Department of Radiology, University of Yamanashi, Department of Radiation Oncology, Tohoku University Graduate School of Medicine, Department of Advanced Biomedical Imaging, University of Yamanashi

Abstract Preview: Purpose: We evaluated the accuracy of a new AI-based fully automated planning software in stereotactic body radiotherapy (SBRT) for early-stage lung cancer.
Methods: We collected data from 125 pati...

Reconstructing Radiopharmaceutical Distributions Using Coded Aperture Tomography with Photon Counting Detector

Authors: David P. Adam, Xun Jia, Youfang Lai, Yuncheng Zhong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University

Abstract Preview: Purpose: Radiopharmaceutical therapy is experiencing a resurgence in interest due to its potential of treating widespread metastatic disease in a patient-specific manner. Accurately measuring and desc...

Shape-Optimized Radiation-Induced Acoustic Computed Tomography for In Vivo online Monitoring of Radiation Therapy

Authors: Yong Chen, Gilberto Gonzalez, Omprakash Gottam, Liangzhong Xiang

Affiliation: University of California, Irvine, Koneru Lakshmaiah Education Foundation, University of Texas at San Antonio., University of Oklahoma Health Science Center

Abstract Preview: Purpose: Clinics currently lack techniques for real-time, in vivo monitoring of radiation therapy (RT), which is desirable for precise treatment. Radiation-induced acoustic computed tomography (RACT) ...

Simultaneous Motion Estimation and Image Reconstruction with Spatiotemporal Implicit Neural Representation Initial (STINR-SMEIR) for Gas Bubble Motion Artifact Reduction in on-Board CBCT Imaging

Authors: Hua-Chieh Shao, Shanshan Tang, Jing Wang, Kai Wang, You Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, University of Maryland Medical Center

Abstract Preview: Purpose: Artifacts caused by gas bubble movement in the gastrointestinal tract can severely degrade the image quality of on-board abdominal cone-beam computed tomography (CBCT), impacting its utility ...

Simultaneous Synthesis of Lung Perfusion and Ventilation Images from CT Using a Dual-Decoder Residual Attention Network for Lung Disease Diagnosis

Authors: Li-Sheng Geng, David Huang, Haoze Li, Xi Liu, Meng Wang, Tianyu Xiong, Ruijie Yang, Weifang Zhang, Meixin Zhao

Affiliation: School of Physics, Beihang University, Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Department of Radiation Oncology, Peking University Third Hospital, Department of Nuclear Medicine, Peking University Third Hospital, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: This study aimed to develop a deep learning-based framework for simultaneously generating lung perfusion and ventilation images from three-dimensional computed tomography (3D CT) images.
M...

Spatial Resolution Degradation in Weekly Computed Tomography Quality Control and Implications for X-Ray Tube Replacement

Authors: Hadley Anna DeBrosse, Kevin J. Little

Affiliation: The Ohio State University

Abstract Preview: Purpose: This work examines the consistency and pattern of spatial resolution degradation in weekly quality control (QC) testing prior to CT tube failure and replacement and investigates potential cor...

Streamlining Direct-to-Unit Clinical Set-Ups for Radiation Therapy

Authors: Lori Buchholtz, Alison Garda, Chris L. Hallemeier, Kathryn L. Kolsky, Han Liu, Joseph John Lucido, Marisa Schinter, Andrew J. Veres, Sara Walerak

Affiliation: Mayo Clinic

Abstract Preview: Purpose: The C_START initiative aims to streamline and simplify the Direct-to-Unit (DtU) clinical setup and treatment planning process for photon radiation therapy, particularly for emergent cases suc...

Supercomputing-Enabled CT Virtual Imaging Trials: A Population-Scale Pilot Study

Authors: Ehsan Abadi, Zakaria Aboulbanine, Nicholas D Felice, David Fenwick, Anuj J. Kapadia, Cindy Marie McCabe, Jayasai Ram Rajagopal, Ehsan Samei

Affiliation: Duke University, Oak Ridge National Laboratory, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose:
Virtual imaging trials (VITs) offer a computational alternative to clinical imaging trials leveraging virtual patients, scanners, and interpreters to assess imaging questions. To provide m...

Text-Conditioned Latent Diffusion Model for Synthesis of Contrast-Enhanced CT from Non-Contrast CT

Authors: Yizheng Chen, Michael Gensheimer, Mingjie Li, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose: Automatically translating non-contrast to contrast-enhanced computed tomography (CT) images is critical for improving clinical workflow, reducing heathcare cost, minimizing radiation exposure...

Time and Energy-Encoded CT Reconstruction

Authors: Shusen Jing, Qihui Lyu, Dan Ruan, Ke Sheng, Qifan Xu

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose: Conventional computed tomography (CT) measures the collective attenuation of primary photon fluence and then reconstructs the 3D images without using the timing information of individual phot...

Time-Resolved CBCT: A Novel Solution for Motion Management

Authors: Bulent Aydogan, Xiaochuan Pan, Erik Pearson, Zheng Zhang

Affiliation: The University of Chicago

Abstract Preview: Purpose: Motion management remains one of the significant challenges in external beam radiation therapy (RT). We are developing time-resolved cone-beam computed tomography (trCBCT) for imaging during ...

Tin-Filtered Spectral Shaping Technique in Clinical Photon-Counting CT: Impact on Noise Magnitude By Object Size, Radiation Dose, and Spectral Reconstruction Type

Authors: Xinhui Duan, Vivek Nair, Liqiang Ren, KyuHo Song, Kuan Zhang, Yue Zhang

Affiliation: Department of Radiology, UT Southwestern Medical Center

Abstract Preview: Purpose: To evaluate how tin-filtered spectral shaping in clinical photon-counting computed tomography (PCCT) affects noise magnitude across varying object sizes, radiation doses, and spectral reconst...

To Establish Local Diagnostic Reference Levels (DRLs) for Head and Neck Computed Tomography (CT) Exams in Abuja, Nigeria, and to Investigate the Performance of Brain Metastasis (BM) and Brain Lesion (BL) Segmentation Techniques Using U-Net Models.

Authors: Nuraddeen Nasiru Garba, Kalpana M Kanal, Abdullahi Mohammed, Rabiu Nasiru, Muhammad SHAFIU Shehu, Daniel Vergara, Joseph Everett Wishart

Affiliation: AHMADU BELLO UNIVERSITY, ZARIA, University of Washington

Abstract Preview: Purpose: To establish local Diagnostic Reference Levels (DRLs) for head and neck computed tomography (CT) exams in Abuja, Nigeria, and to investigate the performance of brain metastasis (BM) and brain...

Towards AI-Driven Adaptive Radiotherapy: Developing a Framework for Utilizing Large-Vision Models in Head-and-Neck Cancer Treatment.

Authors: Anthony J. Doemer, Bing Luo, Benjamin Movsas, Humza Nusrat, Farzan Siddiqui, Chadd Smith, Kundan S Thind, Kyle Verdecchia

Affiliation: Department of Physics, Toronto Metropolitan University, Henry Ford Health

Abstract Preview: Purpose: Large-vision models (LVMs) are rapidly emerging, yet their application in radiation oncology remains largely unexplored. This study investigates the potential of LVMs for offline adaptive rad...

Tumor Density on Time-Weighted Mid-Position Images for Thoracic Tumors

Authors: Katrinus Keijnemans, Eric S. Paulson, An Tai

Affiliation: Department of Radiotherapy, University Medical Center Utrecht, Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Time-weighted mid-position images (MidPs), derived from four-dimensional computed tomography (4DCT) via deformable image registration (DIR), are frequently selected for treatment planning due...

Using Contrast-Enhanced Computed Tomography for Non-Invasive Lung Shunt Fraction Prediction in Yttrium-90 Radioembolization

Authors: Roger Eric Goldman, Adrianna Imani Johnson Carter, Talia Marx, Brahim Mehadji, Emilie Roncali, Catherine T. Vu

Affiliation: UC Davis, Department of Radiology, UC Davis Health

Abstract Preview: Purpose:
Accurate estimation of the Lung Shunt Fraction (LSF) is critical for yttrium-90 (90Y) radioembolization treatment planning to minimize risks of excessive lung irradiation due to arterio-ve...

Validating a Pre-Existing CT HU-to-Mass Density Curve for Direct Dose Calculation on High Quality Cbcts

Authors: Casey E. Bojechko, Tricia Chinnery, Grace Gwe-Ya Kim, Xenia Ray

Affiliation: University of California San Diego

Abstract Preview: Purpose: To evaluate the use of a calibration curve generated from the CT simulator for direct dose calculation on cone beam computed tomography (CBCT) images taken with the on-board imaging system. T...

Validation and Benchmarking of Mirdct Software for Organ Dose Estimation in Routine CT Protocols

Authors: Jared Baggett, Wesley E. Bolch, Lukas M. Carter, Robert Joseph Dawson, Laura Dinwiddie, Gunjan Kayal, Adam Leon Kesner, Harry Marquis, Juan Camilo Ocampo Ramos, Stefan Wehmeier

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, University of Florida, MD Anderson

Abstract Preview: Purpose: Accurate organ dose estimation in computed tomography (CT) has gained attention due to the increasing global utilization of CT imaging. MIRDct, a specialized CT dosimetry software, has recent...

Voxel-Based Micro-Yucatan Minipig Phantoms for Use in Internal Dosimetry

Authors: John P. Aris, Wesley E. Bolch, Natalia Estefania Carrasco-Rojas, Ann M. Chan, Chansoo Choi, Aitor Gallastegui Menoyo, Rowan James Milner, Bangho Shin, Maria M. Von Chamier

Affiliation: University of Florida

Abstract Preview: Purpose: In preclinical studies, minipigs serve as valuable experimental models for predicting absorbed doses due to their anatomical and physiological similarities to humans. However, minipig computa...