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Results for "cross platform": 50 found

4D Monte Carlo Dose Evaluation for Mobile Targets in a Magnetic Field

Authors: Odunola Grace Babawale, B. Gino Fallone, Alireza Gazor, Andrei D. Ghila, Patricia A. K. Oliver, Michael W. Reynolds, Keith D. Wachowicz, Tania Rosalia Wood, Shima Y. Tari, Eugene Yip, Jihyun Yun

Affiliation: Nova Scotia Health, Dept. of Medical Physics and Dalhousie University, Dept. of Physics and Atmospheric Science, Dept. of Radiation Oncology, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta; MagnetTx Oncology Solutions, www.magnetTX.com, Department of Medical Physics, Arthur J. E. Child Comprehensive Cancer Centre, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta, Department of Medical Physics, BC Cancer, Medical Physics Division, Department of Oncology, University of Alberta and Department of Medical Physics, Cross Cancer Institute

Abstract Preview: Purpose: To evaluate the dose to a moving target and its surroundings in a magnetic field using 4D-Monte-Carlo (MC) simulation.
Methods: The study utilizes a previously validated MC model of our li...

A Comparative Study of Hypersight and Truebeam Cone Beam Computed Tomography Image Quality

Authors: Sorour Hosseini, YuHuei Jessica Huang, Thomas Boyd Martin, Geoffrey S. Nelson, Nicholas Pierre Nelson, Hui Zhao

Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah

Abstract Preview: Purpose: To evaluate image quality—including noise, contrast-to-noise ratio (CNR), uniformity, and low-contrast visibility (LCV)—on the HyperSight and TrueBeam cone-beam computed tomography (CBCT) pla...

A Customizable Phantom Insert Design for Testing Deformable Image Registration with Simulated Respiratory Motion

Authors: Mubasheer Chombakkadath, Tara E. Tyson, Iris Z. Wang

Affiliation: Roswell Park Comprehensive Cancer Center, University at Buffalo (SUNY)

Abstract Preview: Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART). Existing DIR phantoms either simulate tumor shape or volume changes but lack comprehensive motion simulati...

A Dual Energy CT-Guided Intelligent Radiation Therapy Platform

Authors: Jiayi Chen, Manju Liu, Ning Wen, Haoran Zhang, Yibin Zhang

Affiliation: Department of Radiation Oncology, Ruijin Hospital, Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Duke Kunshan University, Department of Radiation Oncology,Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

Abstract Preview: Purpose: This study introduces a novel Dual Energy CT (DECT)-Guided Intelligent Radiation Therapy (DEIT) platform designed to streamline and optimize the radiotherapy process. The DEIT system combines...

A GUI-Based Python Platform for the Quantification of Pre-Clinical Planar Optical Imaging Using 3D Anatomical Information

Authors: Bryan Bednarz, Malick Bio Idrissou, Campbell Haasch, Reinier Hernandez

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin–Madison, University of Wisconsin - Madison

Abstract Preview: Purpose: Quantitative optical imaging is a powerful tool in murine models for assessing tumor growth and metastatic spread using bioluminescence imaging (BLI) and for detecting radiopharmaceutical upt...

A Novel Approach to Preclinical Intensity-Modulated Radiotherapy Using an Open-Source Ring-Based Compensator Device and Inverse Treatment Planning System

Authors: Benjamin R. Awad, Bulent Aydogan, Howard J Halpern, Erik Pearson, Gage H. Redler, Jordan M. Slagowski, Rajit Tummala, Autumn E. Walter-Denzin, Jimmy Zydlo

Affiliation: University of Wisconsin-Madison Department of Human Oncology, University of Oxford, The University of Chicago, Moffitt Cancer Center, California State University, Fresno, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Small animal models are crucial in cancer research to develop, validate, and translate basic scientific hypotheses into clinical advancements. This study aims to make small animal intensity-m...

A Plan Complexity Comparison between Monaco and Eclipse - Meta Analysis of 17,000 Plans and 30,000 Beams

Authors: Christopher Colyer, Leon F Dunn, Jonathan Dunning, Simon Goodall, Andy Schofield

Affiliation: GenesisCare

Abstract Preview: Purpose: Modern radiotherapy is characterized by complex treatment plans utilizing dynamic MLCs, gantry positions and recently, collimator rotations. The purpose of this work was to compare the plan c...

A Quantitative Analysis of Hypersight CBCT Image Quality Using a Phantom-Based Approach Under Different Scatter Conditions

Authors: Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Joseph Shields, Christopher Tyerech

Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pennsylvania, UPMC

Abstract Preview: Purpose: HyperSight is a new platform for image-guided radiation therapy, offering advanced reconstruction algorithms, a large field-of-view, and rapid acquisition times. To validate the performance o...

Advanced Modeling of Singlet Oxygen Distribution in Pleural Cavity Photodynamic Therapy Using Validated Geometric Standardization

Authors: Hongjing Sun, Timothy C. Zhu

Affiliation: University of Pennsylvania

Abstract Preview: Purpose: This study aims to develop a model of singlet oxygen distribution in pleural photodynamic therapy (PDT) by combining standardized anatomical coordinates with CT-validated geometry reconstruct...

An Automated Solution to Staged Treatments for Arteriovenous Malformations in Gammaknife

Authors: Strahinja Stojadinovic, Robert Timmerman, Yulong Yan

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas Southwestern Medical Center, University of Texas Southwestern Medical Center

Abstract Preview: Purpose: Radiosurgery for large (>10cc) arteriovenous malformations (AVMs) poses significant challenges due to increased risks of complications and lower obliteration rates. To mitigate toxicity, larg...

Automated Multimodal Image Registration for Prostate Bed Radiation Treatment

Authors: Quan Chen, Xue Feng, Chunhui Han, Gaofeng Huang, Trevor Ketcherside, Yi Lao, Yun Rose Li, An Liu, Bo Liu, Kun Qing, William T. Watkins

Affiliation: Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, City of Hope National Medical Center, Mayo Clinic Arizona, Carina Medical LLC

Abstract Preview: Purpose: New treatment platforms such as Ethos (Varian Medical Systems) allow the introduction of multi-modal imaging into adaptive radiotherapy workflow to facilitate an up-to-date view of patients’ ...

Automated Quantification of Irradiation-Induced Effects on Ribosome Biogenesis Using Foundational AI Model and Image Analysis

Authors: Kyle J. Wang, Yading Yuan

Affiliation: Bergen County Technical High School, Columbia University Irving Medical Center, Department of Radiation Oncology

Abstract Preview: Purpose: Genotoxic cancer therapies inevitably damage normal cells, particularly circulating hematopoietic cells, posting a risk for therapy-induced leukemia. This study aims to develop an automated i...

BEST IN PHYSICS IMAGING: Revolutionizing Neurocognitive Dynamic Pattern Discovery with Self-Supervised AI in Functional Brain Imaging

Authors: Lei Xing, Zixia Zhou

Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Stanford University, Stanford

Abstract Preview: Purpose: Functional brain imaging techniques, such as functional magnetic resonance imaging (fMRI), generate high-dimensional, dynamic data reflecting complex neural processes. However, extracting rob...

Comparative Analysis of Quantum-Classical Hybrid and Traditional Deep Learning Approaches for Chest X-Ray Image Classification

Authors: Ji Hye Han, Yookyung Kim, Jang-Hoon Oh, Heesoon Sheen, Han-Back Shin

Affiliation: Ewha Womans university, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, High-Energy Physics Center, Chung-Ang Universit, Ewha Womans University, Kyung Hee University Hospital

Abstract Preview: Purpose: Chest X-rays are critical for diagnosing conditions such as pneumonia, tuberculosis, and COVID-19. Although deep learning (DL) approaches, especially convolutional neural networks, have signi...

Development of Cross-Platform Application for Radiation Contamination Assessment

Authors: Wesley E. Bolch, Lotem Buchbinder Shadur, Natalia Estefania Carrasco-Rojas, Chansoo Choi, Robert Joseph Dawson, Shaheen Dewji, John Francis, Emmanual Mate-Kole, Wyatt Smither, Yitian Wang

Affiliation: Georgia Tech, University of Florida, Nuclear and Radiological Engineering and Medical Physics Programs, Georgia Institute of Technology

Abstract Preview: Purpose: Develop a software application capable of assessing the radiation contamination of military service members and members of the general public for fast, on-site radiological triage. The softwa...

Development of a Fast Quality Assurance Software Tool for Helical Online Adaptive Radiation Therapy

Authors: Guang-Pei Chen, Mi Huang, Haidy G. Nasief, Eric S. Paulson

Affiliation: Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Recently, kV imaging has been integrated into the Accuray Radixact platform, facilitating online adaptive and scan-plan-treat workflows with helical delivery in the near future. In order to s...

Do We Need Pediatric-Specific Models for Radiotherapy Auto-Contouring? a Comparative Study of Pediatric and Adult-Trained Tools

Authors: Gregory T. Armstrong, James E. Bates, Christine V. Chung, Lei Dong, Ralph Ermoian, Jie Fu, Christine Hill-Kayser, Rebecca M. Howell, Meena S. Khan, Sharareh Koufigar, John T. Lucas, Thomas E. Merchant, Taylor Meyers, Tucker J. Netherton, Constance A. Owens, Arnold C. Paulino, Sogand Sadeghi

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, St. Jude Children's Research Hospital, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, St. Jude Children’s Research Hospital, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, University of Washington/ Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences

Abstract Preview: Purpose: Clinical workflows often rely on auto-segmentation tools trained on adult data, which may exhibit suboptimal performance in pediatric imaging due to inherent anatomical variations and smaller...

Dosimetric Assessment of Spatially Fractionated Radiation Therapy on Prostate Cancer Cases: Our Experience in Nsia-Luth Cancer Center, Lagos

Authors: Adebayo Abe, Samuel Olaolu Adeneye, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Sylvester Entonu, Muhammad Habeebu, Adedayo O. Joseph, Oluwaseyi Oderinde, Oluwadara Ojediran, Margaret Dideolu Taiwo

Affiliation: University of Ibadan, University of Lagos, Missouri University of Science and Technology, Purdue University, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre

Abstract Preview: Purpose:
Spatially Fractionated Radiation Therapy (SFRT) is an advanced radiotherapy technique designed to deliver highly heterogeneous radiation doses, aiming to optimize tumor control while minim...

Dosimetric Impact of Calculation Grid Size in ZAP-X Stereotactic Radiosurgery

Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang

Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center

Abstract Preview: Purpose: ZAP-X is the newest cranial stereotactic radiosurgery (SRS) platform. Small-volume structures usually found in the head and neck may be susceptible to dose-volume averaging, which has not bee...

Dosinme: A 3D Visualization Platform for Internal Dosimetry and Radionuclide Behavior in Computational Human Phantoms

Authors: Lotem Buchbinder Shadur, Shaheen Dewji, Martin Graffigna, Alejandro Rafael Martinez, Emmanuel Mate-Kole, Antonio McClain, Samuel Taylor, Jeffrey Wang

Affiliation: Student, Nuclear and Radiological Engineering and Medical Physics Programs, Georgia Institute of Technology

Abstract Preview: Purpose: DosInMe is an internal dosimetry visualization tool developed by the Radiological Engineering, Detection, and Dosimetry Laboratory at Georgia Tech to assist researchers and professionals in v...

Enhancing Dosimetric Conformity in Single-Energy Bragg Peak Flash Therapy Using Aperture-Based Techniqu

Authors: Chin-Cheng Chen, Chingyun Cheng, Longfei Diao, Benjamin Durkee, Minglei Kang, Haibo Lin, LeLe Liu, Yangguang Ma, Xuanqin Mou, YunTong Pei, Charles B. Simone, YuFei Wang, Xueqing Yan, Xingyi Zhao, Wang Zhengda

Affiliation: Peking University, St. Jude Children's Research Hospital, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, School of Software Engineering, Xi’an Jiaotong University, School of information and communications engineering, Faculty of electronic and information engineering, Xi’an Jiaotong University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: This study evaluates the effectiveness of apertures in improving lateral dose falloff in proton pencil beam scanning (PBS) single-energy Bragg peak (SEBP) FLASH radiotherapy (RT). The approac...

Enhancing Medical Physics Education: From Student Needs to a Moodle-Based LMS

Authors: Paul B. Ravindran

Affiliation: Christian Institute of Health Sciences and Research

Abstract Preview: Purpose: In the past decades, Master's programs in Medical Physics in India have made significant strides, though many have faced challenges in accessing adequate resources for didactic lectures and p...

Evaluating Commercial Auto-Segmentation Software: Is Performance on Pediatric Organs-at-Risk Accurate?

Authors: Gregory T. Armstrong, James E. Bates, Lei Dong, Ralph Ermoian, Jie Fu, Christine Hill-Kayser, Rebecca M. Howell, Sharareh Koufigar, John T. Lucas, Thomas E. Merchant, Tucker J. Netherton, Sogand Sadeghi

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, St. Jude Children's Research Hospital, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, St. Jude Children’s Research Hospital, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, University of Washington/ Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: This study evaluates the adaptability and limitations of commercially available (MIM, RayStation) tools trained on predominately adult datasets (ages 20–60+ years) for delineating organs at r...

Evaluating the Impact of Different Deface Algorithms on the Deep Learning Segmentation Software Performance

Authors: Ali Ammar, Quan Chen, Yi Rong, Libing Zhu

Affiliation: Mayo Clinic Arizona

Abstract Preview: Purpose: To investigate how defacing algorithms, essential for patient privacy in data sharing, impact AI-based segmentation performance in CT imaging for radiation therapy. This study evaluates wheth...

Expanding the Reach: Integrating AI-Generated Auto Contours Via Ray Station’s Deep Learning Segmentation into Diverse Treatment Planning Systems

Authors: Raghavendra Raghavendra, Kanaparthy Raja Muralidhar, Venkataramanan Ramachandran, Srinivas Srinivas

Affiliation: Karkinos Healthcare

Abstract Preview: Purpose: This study explores the Integrating AI-Generated Auto Contours via Ray Station’s Deep Learning Segmentation into Diverse Treatment Planning Systems.
Methods: The research encompassed a gro...

Failure Mode and Effects Analysis (FMEA) on Use of Surface Guided Imaging

Authors: Victoria Noelle Bry, Tamara Egan, Eric C. Ford, Angelia Landers, Juergen Meyer

Affiliation: Fred Hutch Cancer Center, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington

Abstract Preview: Purpose: Surface guided radiation therapy (SGRT) can improve patient safety, however, its complex integration may expose processes to increased risk of error. This work identifies potential failures f...

Feasibility of Using a Dynamic-Platform with High-Resolution Patient-Specific QA Device for Periodic and Patient-Specific-QA in Respiratory-Gated Radiotherapy Lung SBRT Treatment

Authors: Tae Kyu Lee

Affiliation: Allina Health

Abstract Preview: Purpose: To assess the feasibility of a dynamic-platform integrated with high-resolution patient-specific-quality-assurance (PSQ device for periodic quality assurance (PQA) and PSQA in respiratory-gat...

Implementation of an Innovative Digital Competency Record System

Authors: Benjamin J. Sintay, Caroline Vanderstraeten, David B. Wiant

Affiliation: Fuse Oncology, Cone Health

Abstract Preview: Purpose: The Joint Commission (JC) mandates that healthcare organizations establish and evaluate staff competencies to ensure safe and effective patient care. In the context of increasing sub-speciali...

Investigating the Radiation Chemistry of Flash Radiation Therapy through Electron Paramagnetic (EPR) Spectroscopy

Authors: Ramin Abolfath, Alexander Baikalov, Stefan Bartzsch, Nolan M. Esplen, Alan Eduardo Lopez Hernandez, Emil Schueler

Affiliation: MD Anderson Cancer Center, PI Experimental Medical Physics, Institute of Radiation Medicine (IRM), Helmholtz Munich, Germany, Howard University, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: FLASH radiation therapy (FLASH-RT) leverages ultra-high dose rates (UHDR) to spare normal tissue as compared to conventional (CONV)-RT while preserving tumor control; this is termed the FLASH...

Investigation of Metallic Artefact Reduction Capabilities of Hypersight Enabled Platforms

Authors: Harald Keller, Iymad Mansour, Jeff D. Winter

Affiliation: Princess Margaret Cancer Centre

Abstract Preview: Purpose: The growing number of adaptive therapy applications is motivating image segmentation and direct dose calculation on CBCT. The purpose of this investigation is to evaluate the recently release...

Leveraging Codex-Based Spatial Profiling of the Tumor Microenvironment in Concurrent Radiation Therapy and Immunotherapy

Authors: Todd A Aguilera, Bassel Dawod, Sebastian Diegeler, Eslam Elghonaimy, Purva Gopal, Jiaqi Liu, Hao Peng, Arely Perez Rodriguez, Nina N. Sanford, Robert Timmerman, Megan B Wachsmann, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center

Abstract Preview: Purpose: This study pioneers the integration of CODEX (co-detection by indexing)-based spatial profiling and advanced computational techniques to investigate the tumor immune microenvironment (TIME) i...

Low-Cost Image Quality Assurance Phantom Customization Via Additive Manufacturing

Authors: Sarah E. Holler, Daniel Johnson

Affiliation: Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: As the technological availability of modern clinical infrastructure increases in resource-restricted regions of the world, the needs to maintain quality standards of practice need not be hamp...

Moving Away from Measuring Everything - Implementing 3D Recalculation in a Large Networked Radiotherapy Institution to Replace Routine IMRT / VMAT QA

Authors: Eujin Chan, Christopher Colyer, Leon F Dunn, Jonathan Dunning, Michael Grace, Onno Kamst, Alex Livingstone, Thulani Nyathi, Vladimir Sashin, Philip Satory, Hilmar Schachenmayr, Brindha Subramanian, Lindsay J. Tremethick, Luke Webb

Affiliation: GenesisCare

Abstract Preview: Purpose: The purpose of this work is to outline the methodology and results from the implementation of a 3D recalculation software to replace IMRT/VMAT PSQA measurement across a large, networked radio...

Multi-Sid Optimization for 4 Pi Robotic Radiotherapy

Authors: Qihui Lyu, Dan Ruan, Ke Sheng, Jingjie Yu

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose: The robotic arm radiotherapy platform enables flexible delivery of non-coplanar and non-isocentric radiotherapy with variable Source-to-Isocenter Distances (SIDs). However, the high degrees o...

Multi-Vendor Validation of a Deep Learning-Based Synthetic CT Generation Model for MR-Only Radiotherapy Planning in the Pelvis

Authors: Gregory Bolard, Rabten Datsang, Sarah Ghandour, Timo Kiljunen, Pauliina Paavilainen, Sami Suilamo, Katlin Tiigi

Affiliation: Turku University Hospital, Virginia Commonwealth University, MVision AI, North Estonia Medical Centre, Docrates Cancer Center, Hopital Riviera-Chablais

Abstract Preview: Purpose: To verify the performance of a vendor-neutral deep learning model for synthetic CT generation from T2-weighted and balanced steady-state MR sequences to support both MR-only simulation and MR...

Opentps: An Open-Source Radiotherapy Treatment Planning System to Foster Research, Innovation, and Education in Medical Physics

Authors: Ana Maria Barragan Montero, Damien Dasnoy, Sylvain Deffet, Valentine Dormal, Colin Gaban, Melanie Ghislaine, Valentin Hamaide, Guillaume Janssens, John A. Lee, Eliot Peeters, Danah Pross, Luciano Rivetti, Benjamin Roberfroid, Romain Schyns, Kevin Souris, Edmond S. Sterpin, Sophie Wuyckens

Affiliation: Ion Beam Applications SA, Hospital Riviera-Chablais, UCLouvain, Multitel, UniversitĂŠ Catholique de Louvain, IBA, Faculty of Mathematics and Physics, University of Ljubljana, Universite Catholique de Louvain

Abstract Preview: Purpose: Treatment planning systems (TPSs) are essential for simulating and optimizing radiotherapy treatments. However, clinical TPSs are expensive software commercialized by private companies and of...

Preliminary Evaluation of a Gpτ-Based Medical Physics Education Tool

Authors: Ramesh Boggula, Jay W. Burmeister, Michael Joiner

Affiliation: Wayne State University, Karmanos Cancer Center, Gershenson ROC, Wayne State University School of Medicine

Abstract Preview: Purpose: Recent advances in large language models such as ChatGPT offer new possibilities for supplementing traditional teaching methods. In this study, we developed a custom GPT-powered tool freely a...

QA Your QA:3 Steps to Ensure a Robust QA Review Workflow.

Authors: Shahid B. Awan, Harold Li, Aba Lippuner

Affiliation: Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: QA review is a necessary component of QA management but is often pushed aside owing to time constraints and overreliance on vendor solutions. At our multicenter institution, we designed a 3-s...

Quantitative Fluorescence Molecular Tomography Guide Radiation Therapy

Authors: Jiahao Chen, Yunwen Huang, Yidong Yang, Shanshan Zhang, Ning Zhao, Cheng Zheng

Affiliation: Department of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China

Abstract Preview: Purpose: To develop a molecular image-guided radiotherapy technique for accurate and effective radiation treatment using quantitative fluorescence molecular tomography (FMT).
Methods: X-ray cone be...

Quantitative SPECT: Comparison across Platforms.

Authors: Rachel Barbee

Affiliation: UT MD Anderson Cancer Center

Abstract Preview: N/A...

Robustness of Deep Learning-Based Motion Compensated 4D-CBCT Reconstruction to out-of-Distribution Data

Authors: Geoffrey D. Hugo, Eric Laugeman, Thomas R. Mazur, Pamela Samson, Kim A. Selting, Zhehao Zhang

Affiliation: University of Illinois, Washington University in St. Louis School of Medicine, WashU Medicine

Abstract Preview: Purpose: To investigate the robustness of a deep learning (DL)-based 4D-CBCT motion-compensated (MoCo) reconstruction method to out-of-distribution data.
Methods: Our developed 4D-CBCT reconstructi...

Routine Quality Monitoring in Abdominal CT Using Global Noise Reference Levels in a 4-Parameter Protocol Summary Plot

Authors: Joke Binst, Hilde TC Bosmans, Niki Fitousi, Bram Miseur, Dimitar Petrov, Kwinten Torfs, Janne Vignero

Affiliation: Qaelum NV, Department of radiology, UZLeuven, Department of imaging and pathology, KULeuven

Abstract Preview: Purpose: Routine quality monitoring in CT abdomen is crucial for ensuring optimal image quality and patient safety, but the simultaneous evaluation of all aspects of importance is challenging. The pur...

Scan Efficiency and Imaging Dose Analysis of Next-Generation Nonstop Gated CBCT for Respiratory Gating Lung Radiotherapy

Authors: Sean L. Berry, Weixing Cai, Laura I. Cervino, Yusuf Emre Erdi, Yabo Fu, Yiming Gao, Daphna Gelblum, Wendy B. Harris, Xiuxiu He, Tianfang Li, Xiang Li, Seng Boh Gary Lim, Jean M. Moran, Mitchell Yu, Hao Zhang

Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Gated CBCT (gCBCT) is commonly employed for respiratory gating lung cancer patients to ensure precise patient setup. However, the scan is time-consuming on C-arm linear accelerators (LINAC) d...

Segmentation Regularized Registration Training Improves Multi-Domain Generalization of Deformable Image Registration for MR-Guided Prostate Radiotherapy

Authors: Lando S. Bosma, Victoria Brennan, Nicolas Cote, ChengCheng Gui, Nima Hassan Rezaeian, Jue Jiang, Sudharsan Madhavan, Josiah Simeth, Neelam Tyagi, Harini Veeraraghavan, Michael J Zelefsky

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, NYU Langone Health, University Medical Center Utrecht, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Deep learning-based deformable image registration (DIR) models often lack robustness when applied to datasets with differing imaging characteristics. We aimed to (1) improve registration netw...

Slit Scanning Delivery Simulation for Flash Radiotherapy

Authors: Muhammad Ramish Ashraf, Dixin Chen, Aaron Garza, Lloyd Emmanuel Kamole Ghomsi, Edward Elliot Graves, Billy W Loo, Stavros Melemenidis, Joseph B. Schulz, Lawrie Skinner, Murat Surucu

Affiliation: Department of Radiation Oncology, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: FLASH radiotherapy, supported by robust preclinical evidence showing an improved therapeutic index, is advancing toward clinical trials. Clinical FLASH treatments will likely require scanning...

Supercomputing-Enabled CT Virtual Imaging Trials: A Population-Scale Pilot Study

Authors: Ehsan Abadi, Zakaria Aboulbanine, Nicholas D Felice, David Fenwick, Anuj J. Kapadia, Cindy Marie McCabe, Jayasai Ram Rajagopal, Ehsan Samei

Affiliation: Duke University, Oak Ridge National Laboratory, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose:
Virtual imaging trials (VITs) offer a computational alternative to clinical imaging trials leveraging virtual patients, scanners, and interpreters to assess imaging questions. To provide m...

Topas-Nbio – Status and Outlook after a Decade of Developments

Authors: Alejandro Bertolet, Jorge Naoki Dominguez Kondo, Bruce A. Faddegon, Kathryn D Held, Nicolas Henthorn, Jay LaVerne, Thongchai Masilela, Stephen J. McMahon, Isaac Meyer, Victor V. Onecha, Harald Paganetti, Jose A. Ramos-Mendez, Jan PO Schuemann, Wook-Geun Shin, Michael Taylor, John Warmenhoven

Affiliation: Massachusetts General Hospital, Queen's University Belfast, Massachusetts General Hospital and Harvard Medical School, University of California San Francisco, University of Manchester, Notre Dame University

Abstract Preview: Purpose: TOPAS-nBio brings a cutting-edge Monte Carlo (MC) simulation framework to the research community to test hypotheses of radiation effects at the nanometer/cell scale. Here, we present the deve...

Toward Harmonized AI-Based Quantitative CT: A Voxel-Printed, Patient Specific Phantom for Cross-Platform Harmonization

Authors: Aditya P. Apte, Joseph O. Deasy, Yusuf Emre Erdi, Anqi Fu, Johannes Hertrich, Andrew Jackson, Usman Mahmood, Jason Ocana, Trahan Sean, Amita Shukla-Dave

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Automated AI-based quantitative CT tools hold immense promise for advancing clinical decision-making, yet their reproducibility and generalizability remain vulnerable to variability in imagin...

Unlocking Adaptive Radiotherapy Flexibility: Integrating Ethos Adaptive Therapy and Halcyon IGRT with Scripting Innovations

Authors: Min Geon Choi, Sean J. Domal, Ruiqi Li, Taoran Li, Mu-Han Lin, Yang Kyun Park, David D.M. Parsons, Justin D. Visak

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, University of Pennsylvania, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Ethos X-ray-guided online adaptive radiotherapy (ART) enables precise, daily adaptive treatments but requires significant resources, limiting widespread adoption. Many treatment sites do not ...

Validation of Radiopharmaceutical Therapy (RPT) Dose Calculation Platforms from Absolute Absorbed Dose Measurement of 225ac

Authors: Bryan Bednarz, Larry A. DeWerd, Sean Jollota, Ahtesham Ullah Khan, Ohyun Kwon, Jeff Radtke

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison

Abstract Preview: Purpose: The accurate quantification of absorbed dose is essential for alpha-emitting radionuclides used in radiopharmaceutical therapy (RPT). This study presents the first direct comparison of physic...