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Results for "dbt optimization": 16 found

A Novel Optimization Algorithm That Improves DVH Based Planning for Direction Modulated Brachytherapy Tandem Applicator.

Authors: Christopher L. Deufel, Suman Gautam, William Y. Song

Affiliation: Virginia Commonwealth University, Mayo Clinic

Abstract Preview: Purpose: Direction modulated brachytherapy creates anisotropic dose distribution from an isotropic source. This study aims to develop a truncated conditional value at risk optimization algorithm for D...

Combining Proton Flash and Spatially Fractionated Radiotherapy โ€“ Experimental and Simulation Based Dosimetric Characterization

Authors: Gulakhshan M Hamad, Sina Mossahebi, Yannick P. Poirier, Amit Sawant

Affiliation: University of Maryland School of Medicine, Maryland University Baltimore

Abstract Preview: Purpose:
The combination of ultra-high dose rate (UHDR) proton therapy, known for normal tissue sparing, with spatially-fractionated radiotherapy (SFRT), promising enhanced tumor control and tissue...

Development of an Orthogonal X-Ray Projections-Guided Cascading Volumetric Reconstruction and Tumor-Tracking Model for Adaptive Radiotherapy

Authors: Penghao Gao, Zejun Jiang, Huazhong Shu, Linlin Wang, Gongsen Zhang, Jian Zhu

Affiliation: Laboratory of Image Science and Technology, Key Laboratory of Computer Network and Information Integration, Southeast University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences

Abstract Preview: Purpose: We propose a cascading framework for time-varying anatomical volumetric reconstruction and tumor-tracking, guided by onboard orthogonal-view X-ray projections.
Methods: We employe multiple...

Dosimetric Characterization of Spatial Fractionation Collimator for Ultra-High Dose Rate Electron Beam

Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Arnab Chakravarti, Nilendu Gupta, Sagarika Jain, Maximilian Stephen Meineke, Allison N. Palmiero, Runhe Tan

Affiliation: The Ohio State University - James Cancer Hospital, Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center, The Ohio State University, The James Cancer Center

Abstract Preview: Purpose: Ultra-High Dose Rate Radiation Therapy (UHDR-RT) induces normal tissue sparing while maintaining iso-effective tumor control compared to conventional methods, known as the โ€œFLASH effectโ€. How...

End-to-End Pre-Planning Needle Trajectory and Dwell Time Optimization for 3D Printable Cervical and Vaginal Templates

Authors: Deidre Batchelar, Michael Kudla, Stephanie Merkl, Tony Teke

Affiliation: BC Cancer - Kelowna

Abstract Preview: Purpose: Preplanning 3D-printed templates for cervical and vaginal brachytherapy is an iterative process, often taking hours to for an individual patient.
This study demonstrates an end-to-end auto...

Evaluating the Impact of Reconstruction Algorithm on Wide-Angle Digital Breast Tomosynthesis System Optimization for Microcalcification Detection

Authors: Xiaoyu Duan, Xinyu Hu, Runqiu Li, Xiang Li

Affiliation: Dukekunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose:
Accurate detection of small-sized microcalcifications (ฮผCalcs) (< 500 ยตm) is critical for early breast cancer diagnosis, requiring optimal imaging systems and reconstruction algorithms. Ho...

Evaluation of the Accumulated Dose in Combined Radiotherapy for Cervical Carcinoma Using DVH Addition and Deformable Image Registration Based on Optimization of BT Boost Region in EBRT

Authors: Qiu Tang, Yeqiang Tu, Jiahao Wang, Lu Wang

Affiliation: Women's Hospital School of Medicine Zhejiang University, Hangzhou Women's Hospital

Abstract Preview: Purpose: The BT boost regions were previously delineated and optimized during EBRT planning process. The differences of DVH parameters addition (PA), deformable dose summation (DS) with BT boost regio...

Impact of Diacetylene Polymer Chemistry on Real-Time Radiochromic Film Dosimetry

Authors: Rohith Kaiyum, Ozzy Mermut, Alexandra Rink

Affiliation: Department of Medical Biophysics, University of Toronto, Department of Physics and Astronomy, York University

Abstract Preview: Purpose: To investigate the relationship between chemical features and real-time response to ionizing radiation dose of radiochromic diacetylene crystals.
Methods: A number of radiochromic diacetyl...

Incorporating Cyclic Group Equivariance into Deep Learning for Reliable Reconstruction of Rotationally Symmetric Tomography Systems

Authors: Fang-Fang Yin, Lei Zhang, Yaogong Zhang

Affiliation: Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Rotational symmetry is an inherent property of many tomography systems (e.g., CT, PET, SPECT), arising from the circular arrangement or rotation of detectors. This study revisits the image re...

Integrated Catheter Position and Dwell Time Optimization for Focal Dose Escalation in Prostate HDR Brachytherapy

Authors: Bryan Bednarz, John M. Floberg, Joseph B. Schulz, Jordan M. Slagowski

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Catheter placement for high-dose-rate brachytherapy (HDR BT) is clinician dependent and potentially suboptimal for delivering simultaneous integrated boosts to intraprostatic gross tumor volu...

Investigating the Flash Effect: Uncovering Brain Sparing and Cognitive Preservation across Varying Dose Rates in Whole-Brain Irradiation of in-Vivo Mouse Models

Authors: Denise Dunn, Scott R. Floyd, Tyler V. Kay, Anna Lynnette-Price, Eric L. Martin, Stepan Mikhailov, Taylor Nguyen, Mark Oldham, Victoria J. P. Radosova, Zachary J. Reitman, Ramona Rodriguiz, Andrew Thompson, William Wetsel, Seth Wilcox, Ying Wu

Affiliation: Duke University Mouse Behavior Core, Department of Physics, Duke University, Medical Physics Graduate Program, Duke University, Duke University Medical Physics Program, Duke University, Duke University Mouse Behavioral and Neuroendocrine Analysis Core Facility, Department of Radiation Oncology, Duke University Medical Center

Abstract Preview: Purpose: FLASH radiation therapy (RT) shows promise for reducing normal tissue damage, though its mechanisms remain unclear. Using an in-vivo model with the High Intensity Gamma-ray Source (HIGS) lina...

Optimization-Based Image Reconstruction Regularized with Inter-Spectral Structural Similarity for Limited-Angle Dual-Energy Cone-Beam CT

Authors: Chih-Wei Chang, Junbo Peng, Richard L.J. Qiu, Justin Roper, Xiangyang Tang, Tonghe Wang, Huiqiao Xie, Xiaofeng Yang, David Yu

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Emory Univ, Emory University, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Limited-angle dual-energy (DE) cone-beam CT (CBCT) is considered a promising solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, ...

Small but Mighty: A Lightweight and Computationally Efficient Model for Deformable Image Registration

Authors: Hengjie Liu, Dan Ruan, Ke Sheng, DI Xu

Affiliation: Physics and Biology in Medicine, University of California, Los Angeles, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, Los Angeles

Abstract Preview: Purpose:
State-of-the-art deep learning-based deformable image registration often uses large, complex models directly adapted from computer vision tasks but achieves only comparable performance to ...

Streamlining Orthovoltage QA: Feasibility of IC Profiler Dosimetry and Workflow Optimization

Authors: Huixiao Chen, Zhe (Jay) Chen, MinYoung Lee, Sameer Taneja

Affiliation: Yale School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: Superficial radiation therapy uses low-energy x-rays to treat various types of cancers, including non-melanoma skin cancers, and dermatological conditions such as keloid scars, mycosis fungoi...

The Biological TCP/NTCP Modelling on Oropharyngeal Head-and-Neck Cancer for Patients Treated with Proton Beam Therapy

Authors: Wen C. Hsi, Tae Kyu Lee, Biniam Yo Tesfamicael

Affiliation: Allina Health, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Oklahoma Proton Center

Abstract Preview: Purpose: When minimal dose-variations induced by inter-fractional anatomical-changes and positioning-deviation were found for having limited impact on clinic-outcomes of oropharyngeal head-and-neck (H...

Using a-Si 1200 Epid Portal Dosimetry for VMAT Commissioning

Authors: Ryan Burri, Nazanin Hoshyar, Jerry W. McCoy, Yulin Song, Huma Syed

Affiliation: Bay Pines VA Medical Center

Abstract Preview: Purpose: The study aimed to streamline traditionally manual, iterative, and time-consuming VMAT commissioning process. The goal was to identify an optimal set of MLC dosimetric parameters that minimiz...