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Results for "decay chains": 5 found

A Monte Carlo Simulation Framework for Investigating the Effect of Inter-Track Coupling on H2O2 Productions at Ultra-High Dose Rates

Authors: Ramin Abolfath, Sedigheh Fardirad, Abbas Ghasemizad, Houda Kacem, Marie Catherine Vozenin

Affiliation: University of Guilan, Universite de Lausanne, University Hospital, Geneva, Howard University

Abstract Preview: Purpose: Lower production of H2O2 in water is a hallmark of ultra-high dose rate (UHDR) compared to the conventional dose rate (CDR). The current computational models are in the opposite of the experi...

Addressing Radionuclide Decay Complexities in Targeted Alpha Therapy: A Computational Approach.

Authors: Denis Bergeron, Ryan P Fitzgerald, Ravneet Kaur, Rao Khan

Affiliation: John Hopkins University, NIST Radiation Physics Division, Howard University, National Institute of Standards and Technology

Abstract Preview: Purpose: There is growing interest in short-lived alpha-emitting radionuclides for cancer therapy due to their ability to selectively target and destroy cancer cells while sparing healthy tissue. Howe...

Dosinme: A 3D Visualization Platform for Internal Dosimetry and Radionuclide Behavior in Computational Human Phantoms

Authors: Lotem Buchbinder Shadur, Shaheen Dewji, Martin Graffigna, Alejandro Rafael Martinez, Emmanuel Mate-Kole, Antonio McClain, Samuel Taylor, Jeffrey Wang

Affiliation: Student, Nuclear and Radiological Engineering and Medical Physics Programs, Georgiaย Institute of Technology

Abstract Preview: Purpose: DosInMe is an internal dosimetry visualization tool developed by the Radiological Engineering, Detection, and Dosimetry Laboratory at Georgia Tech to assist researchers and professionals in v...

Poisson Decay in Pharmacokinetics with Imaging in Targeted Alpha Therapy

Authors: Lars R Furenlid, Chiao Huang, Matthew A. Kupinski, Brian W. Miller

Affiliation: University of Arizona, Departments of Radiation Oncology and Medical Imaging, University of Arizona

Abstract Preview: Purpose: To sample random numbers of decay of radiotracers in a pharmacokinetic compartment model for Monte-Carlo simulation of imaging in targeted alpha therapy.
Methods: Time-activity curves (TAC...

Validation of Radiopharmaceutical Therapy (RPT) Dose Calculation Platforms from Absolute Absorbed Dose Measurement of 225ac

Authors: Bryan Bednarz, Larry A. DeWerd, Sean Jollota, Ahtesham Ullah Khan, Ohyun Kwon, Jeff Radtke

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison

Abstract Preview: Purpose: The accurate quantification of absorbed dose is essential for alpha-emitting radionuclides used in radiopharmaceutical therapy (RPT). This study presents the first direct comparison of physic...