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Results for "deep neural": 66 found

A Deep Learning-Based Approach for Rapid Prediction of IMRT/VMAT Patient-Specific Quality Assurance for Online Adaptive Plans Generated with a 0.35T MR-Linac

Authors: Suman Gautam, Tianjun Ma, William Song

Affiliation: Virginia Commonwealth University

Abstract Preview: Purpose: We propose an artificial intelligence (AI)-based method to rapidly predict the patient-specific quality assurance (PSQA) results for magnetic resonance (MR)-guided online adaptive radiation th...

A Modular Approach to Reversible and Stackable Medical Imaging Translation Models: CBCT-Based Synthetic MRI with Multiple U-Nets in Series (MUNETs)

Authors: Eric Chang, Nguyen Phuong Dang, Andrew Lim, Lauren Lukas, Lijun Ma, Yutaka Natsuaki, Zhengzheng Xu, Hualin Zhang

Affiliation: Radiation Oncology, Keck School of Medicine of USC

Abstract Preview: Purpose: Harnessed the power of AI and Deep Learning (DL), Generalized Neural Network models for medical image transformation are trained to predict target images from reference images, often requirin...

A Self-Supervised Deep Learning Approach for Automatic Identification and Metal Artifact Reduction in Cone-Beam CT for Brachytherapy

Authors: Rani Anne', Wenchao Cao, Yingxuan Chen, Wookjin Choi, Firas Mourtada, Yevgeniy Vinogradskiy

Affiliation: Thomas Jefferson University

Abstract Preview: Purpose: In-room mobile cone-beam CT (CBCT) is emerging to enhance high-dose-rate (HDR) brachytherapy workflow using on-demand imaging. However, metal artifacts from X-ray markers inside gynecological...

A Two-Layer, Two-Task Prediction Model Based on 3D Imaging and Residual Networks for Mid-Chemoradiation Tumor Response Prediction on FDG PET for La-NSCLC

Authors: Stephen R. Bowen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Jing Sun, Jiajie Wang, Shouyi Wang, Faisal Yaseen, Xiaojing Zhu

Affiliation: Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Shanghai University of Electric Power, Fred Hutchinson Cancer Center, University of Texas at Arlington

Abstract Preview: Purpose: Accurate prediction of patient response to radiotherapy plays a crucial role in monitoring disease progression and assessing treatment efficacy, enabling clinicians to develop personalized th...

An Image Representation of Radiomics Data for Enhanced Deep Radiomics Analysis with Consideration of Feature Interactions

Authors: Xiaolong Fu, Runping Hou, Md Tauhidul Islam, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine

Abstract Preview: Purpose: To introduce a novel schematic image representation of radiomics data, called OmicsMap, for high-performance deep radiomics analysis. OmicsMap transforms tabular radiomics data into an image ...

Automated Diagnosis of Pancreatic Cancer Using Both Radiomics and 3D-Convolutional Neural Network

Authors: Beth Bradshaw Ghavidel, Benyamin Khajetash, Yang Lei, Meysam Tavakoli

Affiliation: Icahn School of Medicine at Mount Sinai, Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Emory University, Department of Radiation Oncology, Emory University

Abstract Preview: Purpose: Pancreatic cancer is among the most aggressive types of cancer, with a five-year survival rate of approximately 10%. Recent studies show that radiomics and deep learning (DL)-based methods ar...

Automatic 4D Lung PET-CT Segmentation Using Hybrid Deep Neural Network

Authors: Hongyi Jiang, Fang-Fang Yin

Affiliation: Duke University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose:
Imaging moving tissues using PET-CT can be difficult. Separating signal into phases during construction reduces signal count and increases influence of noise. Algorithms that use signal fr...

BEST IN PHYSICS IMAGING: Revolutionizing Neurocognitive Dynamic Pattern Discovery with Self-Supervised AI in Functional Brain Imaging

Authors: Lei Xing, Zixia Zhou

Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Stanford University, Stanford

Abstract Preview: Purpose: Functional brain imaging techniques, such as functional magnetic resonance imaging (fMRI), generate high-dimensional, dynamic data reflecting complex neural processes. However, extracting rob...

Beam Orientation Optimization in IMRT Using Sparse Mixed Integer Programming and Non-Convex IMRT Fluence Map Optimization

Authors: Yabo Fu, Yang Lei, Yu Lei, Haibo Lin, Ruirui Liu, Tian Liu, Kenneth Rosenzweig, Charles B. Simone, Shouyi Wei, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York Proton Center

Abstract Preview: Purpose: Beam orientation optimization (BOO) in intensity-modulated radiation therapy (IMRT) is traditionally a complex, non-convex problem tackled with heuristic methods. This study benchmarks global...

Biologically Guided Deep Learning for MRI-Based Brain Metastasis Outcome Prediction after Stereotactic Radiosurgery

Authors: Evan Calabrese, Hangjie Ji, Kyle J. Lafata, Casey Y. Lee, Eugene Vaios, Chunhao Wang, Lana Wang, Zhenyu Yang, Jingtong Zhao

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Duke Kunshan University, North Carolina State University

Abstract Preview: Purpose: To develop a biologically guided deep learning (DL) model for predicting brain metastasis(BM) local control outcomes following stereotactic radiosurgery (SRS). By integrating pre-SRS MR image...

Brain Tumor Segmentation from Multi-Parametric MRI with Integrated Evidential Uncertainty Estimation

Authors: Sahaja Acharya, Matthew Ladra, Junghoon Lee, Lina Mekki

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University

Abstract Preview: Purpose: Multi-parametric MRI (mpMRI) is widely used for deep learning (DL)-based automatic segmentation of brain tumors. While multi-contrast images concatenated as channels are typically input to ne...

Cerebellar Mutism Syndrome Prediction with 3D Residual Convolutional Neural Network

Authors: Sahaja Acharya, Matthew Ladra, Junghoon Lee, Lina Mekki, Bohua Wan

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University, Department of Computer Science, Johns Hopkins University

Abstract Preview: Purpose: Cerebellar mutism syndrome (CMS) is the most frequently observed complication in children undergoing surgical resection of posterior fossa tumors. Previous work explored lesion to symptom map...

Comparative Analysis of Nine Deep Learning Architectures for Variable Density Grappa 1H Magnetic Resonance Spectroscopy Imaging (MRSI) Reconstruction

Authors: Kimberly Chan, Anke Henning, Mahrshi Jani, Andrew Wright, Xinyu Zhang

Affiliation: Advanced Imaging Research Center (AIRC), UT Southwestern Medical Center

Abstract Preview: Purpose: To evaluate the performance of multiple deep learning architectures for MRSI reconstruction and determine their effectiveness in maintaining high-resolution metabolite mapping while reducing ...

Comparative Analysis of Quantum-Classical Hybrid and Traditional Deep Learning Approaches for Chest X-Ray Image Classification

Authors: Ji Hye Han, Yookyung Kim, Jang-Hoon Oh, Heesoon Sheen, Han-Back Shin

Affiliation: Ewha Womans university, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, High-Energy Physics Center, Chung-Ang Universit, Ewha Womans University, Kyung Hee University Hospital

Abstract Preview: Purpose: Chest X-rays are critical for diagnosing conditions such as pneumonia, tuberculosis, and COVID-19. Although deep learning (DL) approaches, especially convolutional neural networks, have signi...

Construction and Application Study of a Deep Learning-Based Iscout-Guided Precision Radiotherapy Positioning Error Prediction Model for Breast Cancer

Authors: Fangfen Dong, Jiaming Li, Xiaobo Li, Weipei Wang, Zhixin Wang, Bing Wu, Benhua Xu, Yong Yang, Yifa Zhao

Affiliation: Department of Radiation Oncology, Fujian Medical University Union Hospital/Fujian Key Laboratory of Intelligent Imaging and Precision Radiotherapy for Tumors/Clinical Research Center for Radiology and Radiotherapy of Fujian Province (Digestive, Hematologi, Zhangpu County Hospital, School of Medical Imaging, Fujian Medical University

Abstract Preview: Purpose: To explore the construction and clinical application value of a deep learning-based positioning error prediction model, providing a reference for optimizing iSCOUT system-guided precision rad...

Contrast-Free Full Intracranial Vessel Geometry Estimation from MRI with Metric Learning-Based Inference

Authors: Zhaoyang Fan, Eric Nguyen, Dan Ruan, Jiayu Xiao

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiology, University of Southern California, University of Southern California

Abstract Preview: Purpose: MR vessel wall imaging (VWI) has been shown to be effective for evaluating intracranial atherosclerosis disease. However, VWI typically also requires an MR angiography (MRA) in the same imagi...

Deep Learning Based Filter with Back-Projection Operator for CT Reconstruction

Authors: Justus Adamson, Mu Chen, Ke Lu, Zhenyu Yang, Fang-Fang Yin, Rihui Zhang, Yaogong Zhang, Haipeng Zhao, Haiming Zhu, Yuchun Zhu

Affiliation: Shanghai Dacheng Medical Technology, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan

Abstract Preview: Purpose: In filtered back-projection (FBP) reconstruction, conventional filters often reduce noise at the expense of high-frequency details, leading to structural details loss. To address this limitat...

Deep Learning-Based Categorization of Brain Tumours Using Brain MRI : Advancing Precision Medicine in Neuroimaging

Authors: William F.B Igoniye, Belema Manuel, Christopher F. Njeh, O Ray-offor

Affiliation: Indiana University School of Medicine, Department of Radiation Oncology, Department of Radiology, University of Port Harcourt Teaching Hospital

Abstract Preview: Purpose: The accurate and efficient categorization of brain tumors is essential for effective treatment planning and improved patient outcomes. Current MRI-based diagnostic methods are time-intensive ...

Deep Learning-Driven Comparative Analysis of CNN-Based Architectures and High-Order Vision Mamba U-Net (H-vMUNet) for MRI-Based Brain Tumor Segmentation

Authors: Sang Hee Ahn, Nalee Kim, Do Hoon Lim

Affiliation: Samsung Medical Center, Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine

Abstract Preview: Purpose: MRI offers superior soft-tissue contrast, aiding tumor localization and segmentation in radiation therapy, which traditionally relies on oncologists' expertise. This study compares CNN-based ...

Deep-Learning Convolutional Neural Network-Based Breast Cancer Localization for Mammographic Images: A Study on Simulated and Clinical Images

Authors: Xiaoyu Duan, Xiang Li, Wenbo Wan, Lei Zhang, Yiwen Zhang

Affiliation: Duke University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Breast screening has been proved to reduce breast cancer mortality by early detection and treatment for patients. Mammography is the most common and widely used technique for breast cancer sc...

Developing a Comprehensive Multi-Modal Framework for Population-Scale Liver Volumetry: Insights and Predictive Models

Authors: Mustafa Bashir, Diana Kadi, Kyle J. Lafata, Jacob A. Macdonald, Mark Martin, Yuqi Wang, Marilyn Yamamoto

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Electrical and Computer Engineering, Duke University, Department of Radiology, Duke Unversity

Abstract Preview: Purpose: To develop a high-throughput, automated-data-interrogation pipeline for integrating imaging and clinical information to identify key determinants of liver volume (LV), enabling population-sca...

Developing an AI-Driven Predictor for Forecasting Treatment Outcomes in Patients with Early-Stage Breast Cancer

Authors: Lucy Jiang, Chengyu Shi

Affiliation: Department of Radiation Oncology, City of Hope Orange County, Amity Regional High School (10th Grade)

Abstract Preview: Purpose: Early-stage breast cancer is common among females, with typically high local tumor control rates (LCR). Brachytherapy is a common way to achieve LCR following surgery. However, the patients m...

Dual-Domain Reconstruction Network for Nonstop Gated CBCT Imaging: Application in Respiratory Gating Ablative Radiotherapy for Pancreatic Cancer

Authors: Sean L. Berry, Weixing Cai, Laura I. Cervino, Yabo Fu, Daphna Gelblum, Wendy B. Harris, Xiuxiu He, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Boris Mueller, Huiqiao Xie, Mitchell Yu, Hao Zhang

Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Gating ablative radiotherapy for pancreatic cancer accounts for tumor movement due to respiration and typically requires 5, 15, or 25 fractions. Pretreatment imaging verification is essential...

Enhanced Pelvic Organ Segmentation Using LLM-Driven Prompts for Prostate Cancer Low-Dose-Rate Brachytherapy

Authors: Yang Lei, Tian Liu, Ren-Dih Sheu, Meysam Tavakoli, Jing Wang, Kaida Yang, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Emory University

Abstract Preview: Purpose:
The study aimed to improve target and organ at risk (OAR) segmentation in low-dose-rate brachytherapy (LDR-BT) for prostate cancer treatment, by integrating clinical guidelines into deep l...

Evaluating the Impact of Contour Variability on the Effectiveness of Deep Learning Features in Head and Neck Imaging

Authors: Hania A. Al-Hallaq, Xuxin Chen, Anees H. Dhabaan, Elahheh (Ella) Salari, Xiaofeng Yang

Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose:
Radiomics image analysis could lead to the development of predictive signatures and personalized radiotherapy treatments. However, variations in delineation are known to affect hand-crafte...

Evaluation of AI-Generated Synthetic 4DCT from 3DCT for Radiotherapy Planning

Authors: Shinichiro Mori, Isabella Pfeiffer, Chester R. Ramsey, Alexander Usynin

Affiliation: Thompson Proton Center, National Institutes for Quantum Science and Technology, Thompson Cancer Survival Center

Abstract Preview: Purpose: Four-dimensional CT imaging (4DCT) has become a standard tool for managing respiratory motion in radiation therapy. However, many treatment delivery systems and most diagnostic CT scanners la...

Evaluation of Daily Respiratory Pattern from a Single Free-Breathing Cone Beam CT Scan

Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Xiuxiu He, Tianfang Li, Xiang Li, Hao Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose:
This work aims to develop an innovative technique to evaluate patients’ daily respiratory pattern using three-dimensional (3D) deformation vector fields (DVF) derived from a free-breathing...

Fast 3D Scintillation Dosimetry Using Single View Deep Learning Reconstruction

Authors: Louis Archambault, Nicolas Drouin, Alexis Horik, Simon Thibault

Affiliation: Département de Physique, de Génie Physique et D'optique, et Centre de Recherche sur le Cancer, Université Laval, Département de Physique, de Génie Physique et D'optique, et Centre d'optique, photonique et laser, Université Laval

Abstract Preview: Purpose: To develop a novel type of real-time 3D dosimeter for the quality assurance of linear accelerators used in external beam radiotherapy.
Methods: An experimental setup was constructed using ...

Generalized 2D Cine Multi-Modal MRI-Based Dynamic Volumetric Reconstruction Using Motion-Aligned Implicit Neural Network with Spatial Prior Embedding

Authors: Ming Chao, Karyn A Goodman, Yang Lei, Tian Liu, Jing Wang, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai

Abstract Preview: Purpose: Real-time volumetric MRI is essential for motion management in MRI-guided radiotherapy (MRIgRT), yet acquiring high-quality 3D images remains challenging due to time constraints and motion ar...

Generating Brain Pseudo-CT from PET-Only Images Using Deep Learning Method

Authors: Pouya Azarbar, Nima Kasraie, Mahsa Shahrbabki Mofrad, Peyman Sheikhzadeh

Affiliation: UT Southwestern Medical Center, Shahid Beheshti University of Medical science, Imam Khomeini Hospital Complex,Tehran University of Medical Sciences, Tehran University of Medical Science

Abstract Preview: Purpose: PET imaging become crucial in diagnosing and managing various diseases, but its key limitation is the lack of detailed anatomical information. Integrating CT-scans with PET images enhances cl...

Generation of Virtual Lung PET Images from CT Data Via Deep Learning for Accelerated Tumor Detection and Preliminary Diagnosis

Authors: Pouya Azarbar, Nima Kasraie, Peyman Sheikhzadeh

Affiliation: UT Southwestern Medical Center, Shahid Beheshti University of Medical science, Imam Khomeini Hospital Complex,Tehran University of Medical Sciences

Abstract Preview: Purpose: Positron Emission Tomography (PET) is crucial for diagnosing and monitoring diseases due to its functional imaging capabilities. However, its high cost, significant radiation exposure, and li...

Geometric Alignment of MV-CBCT and Dual-Layer Kv-CBCT Projections Using Deep Learning

Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Nicholas Lowther, Daniel Morf, Marios Myronakis

Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Womens Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute

Abstract Preview: Purpose: Applications of combined kV-MV CBCT include metal artifact correction and material identification. Difficulties arise, however, when the imagers have misaligned geometric perspectives of the ...

Graph Neural Network with Long Short-Term Memory for CT-Based Macrotrabecular-Massive Hepatocellular Carcinoma Diagnosis

Authors: Enhui Chang, Yunfei Dong, Yifei Hao, Chengliang Jin, Shengsheng Lai, Yi Long, Mengni Wu, Yulu Wu, Ruimeng Yang, Zhenyu Yang, Yue Yuan, Lei Zhang, Wanli Zhang, Yaogong Zhang

Affiliation: Duke Kunshan University, Department of Radiology, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Macrotrabecular-Massive Hepatocellular Carcinoma (MTM-HCC) is one type of liver cancer showed minimum image signature for accurate non-invasive diagnosis. This study aims to develop and evalu...

Hands-on AI Education for Radiology Residents

Authors: Wilfred R Furtado, Gary Y. Ge, James Lee, Jie Zhang

Affiliation: University of Kentucky

Abstract Preview: Purpose: Despite advancements in Artificial Intelligence (AI) and its growing role in clinical practices like radiology, formal AI education remains limited in medical training. This gap contributes t...

High-Resolution Limited-Angle CBCT Image Reconstruction for Non-Coplanar Radiation Therapy Via Dual-Domain Ordered-Subset Neural Representation with Prior Embedding (DDOS-NeRP)

Authors: Yu Gao, Lei Xing, Siqi Ye

Affiliation: Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) scans are often the only option for non-coplanar radiation therapy to prevent potential mechanical collisions. However, the consecutive angular occlusion of pr...

Hybrid Prior-Enhanced Deep Image Prior (HPEDIP) Image Reconstruction for Ultra-Short Scans

Authors: Renee Farrell, Jinkoo Kim, Xin Qian, Ziyu Shu, Zhaozheng Yin, Tiezhi Zhang

Affiliation: Stony Brook Medicine, Washington University in St. Louis, Stony Brook University, Stony Brook University Hospital

Abstract Preview: Purpose: Ultra-short CT scan allows fast imaging speed, dose reduction, and compact system design. We developed a deep image prior (DIP) based reconstruction method named Hybrid Prior-Enhanced Deep Im...

Hyperpolarized 13c Image Superresolution with Deep Learning

Authors: Kofi M. Deh, Tamas Jozsa, Tsang-Wei Tu

Affiliation: Cranfield University, Howard University Hospital, Howard University

Abstract Preview: Purpose: To enhance the quality of hyperpolarized (HP) 13C magnetic resonance images by integrating deep learning with perfusion modeling.
Methods: A convolutional neural network (CNN) and a superr...

Image Similarity Measurement Based on Handcrafted and Deep Learning Radiomics

Authors: John Ginn, Chenlu Qin, Deshan Yang

Affiliation: Duke University, Department of Radiation Oncology, Duke University

Abstract Preview: Purpose: Clinical implementation of auto-segmentation tools has been hindered by poor interpretability and generalizability of AI models, necessitating the development of automated contour quality ass...

Improve the Risk Prediction of Radiation-Induced Esophagitis in Lung IMRT By an Anisotropic Dose Convolution Neural Network

Authors: Ibtisam Almajnooni, Elisabeth Weiss, Lulin Yuan

Affiliation: Virginia Commonwealth University

Abstract Preview: Purpose: We developed a deep learning neural network (DLNN) to predict the risk of radiation-induced esophagitis (RE) during lung cancer radiation therapy based on the spatial dose distribution, for t...

Improving Mammography Diagnosis Accuracy through Global Context and Local Lesion Integration

Authors: Minbin Chen, Xiaoyi Dai, Xiaoyu Duan, Chunhao Wang, Fan Xia, Zhenyu Yang, Fang-Fang Yin, Chulong Zhang, Rihui Zhang

Affiliation: Duke University, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University, The First People's Hospital of Kunshan

Abstract Preview: Purpose: Deep learning (DL)-based mammography diagnosis presents unique challenges, as accurate interpretation requires both global breast condition analysis and local lesion structural information. E...

Improving Post-SRS Brain Metastasis Radionecrosis Diagnosis Accuracy Via Deep Feature Space Analysis

Authors: Evan Calabrese, Scott R. Floyd, Kyle J. Lafata, Zachary J. Reitman, Eugene Vaios, Chunhao Wang, Lana Wang, Deshan Yang, Zhenyu Yang, Jingtong Zhao

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Duke Kunshan University

Abstract Preview: Purpose:
This study proposes a novel neural ordinary differential equation (NODE) framework to distinguish post-SRS radionecrosis from recurrence in brain metastases (BMs). By integrating imaging f...

Improving Segmentation Precision in Prostate Cancer Adaptive Radiotherapy with the Intentional Deep Overfit Learning (IDOL) Approach

Authors: Seungryong Cho, Donghyeok Choi, Joonil Hwang, Byung-Hee Kang, Jin Sung Kim, Eungman Lee, Younghee Park

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, KAIST, Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Ewha Womans University of Medicine

Abstract Preview: Purpose: Radiation therapy (RT) is critical for cancer treatment, but changes in tumor size and shape during therapy challenge precise dose delivery. Adaptive radiation therapy (ART) addresses these v...

Innovative Deep Learning Network for Overall Survival Prediction for NSCLC: Outperforming Pre-Trained Models VGG16 and ResNet50

Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder

Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida

Abstract Preview: Purpose: Early-stage NSCLC patients undergoing SBRT often die due to intercurrent illnesses. However, prediction of overall survival (OS) remains crucial due to the risk of disease recurrence. This st...

Integrating Neuroanatomic Knowledge in Clinical Target Volumes for Glioma Patients Using Deep Learning

Authors: Ali Ajdari, Thomas R. Bortfeld, Christopher Bridge, Gregory Buti, Marcela Giovenco, Fredrik Lofman, Gregory C. Sharp, Helen A Shih, Tugba Yilmaz

Affiliation: Massachusetts General Hospital, RaySearch Laboratories, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Massachusetts General Hospital and Harvard Medical School

Abstract Preview: Purpose: Defining radiation target volumes with accurate integration of the neuroanatomy is one of the major difficulties in designing glioma treatments. We developed a deep learning network for norma...

Inter-Machine Harmonization in Echocardiographic Videos for Predicting Left Ventricular Ejection Fraction

Authors: Akihiro Haga, Ren Iwasaki, Kenya Kusunose, Makoto Miyake, Kenji Moriuchi, Yasuharu Takeda, Hidekazu Tanaka, Hirotsugu Yamada

Affiliation: Department of Cardiovascular Medicine, Nephrology, and Neurology Graduate School of Medicine, University of the Ryukyus, Graduate School of Biomedical Sciences, Tokushima University, Tokushima university, Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Department of Cardiology, Tenri Hospital, Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Division of Heart Failure, Department of Heart Failure and Transplant, National Cerebral and Cardiovascular Center

Abstract Preview: Purpose: Device dependency is a significant challenge in medical AI, potentially limiting generalization performance. This study aimed to develop a robust deep learning model for predicting left ventr...

Interpretable Deep Learning Predicts Metastasis-Free Survival (MFS) from Conventional Imaging for Oligometastatic Castration-Sensitive Prostate Cancer (omCSPC) Using Multi-Modality PSMA PET and CT Imaging.

Authors: Yufeng Cao, Luigi Marchionni, William Silva Mendes, Cem Onal, Lei Ren, Amit Sawant, Nicole L Simone, Philip Sutera, Phuoc Tran

Affiliation: University of Maryland School of Medicine, 9Department of Radiation Oncology, Thomas Jefferson University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, University of Maryland, Baltimore, Baskent University Faculty of Medicine, Department of Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine, Maryland University Baltimore, 8Department of Pathology and Laboratory Medicine, Weill Cornell Medicine

Abstract Preview: Purpose: This study aims to predict 2-yr Metastasis-free survival (MFS) for oligometastatic castration-sensitive prostate cancer (omCSPC) patients treated by metastasis-directed therapy (MDT) by devel...

Lymph Node Malignancy Prediction in Head and Neck Cancer Using a Graph Neural Network

Authors: Liyuan Chen, Meixu Chen, Bowen Jing, Sepeadeh Radpour, Erich Josef Schmitz, David Sher, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Prospective clinical trials have shown that involved nodal radiation therapy (INRT) can substantially improve patients’ quality of life without increasing the risk of elective nodal failure. ...

Memory-Efficient Deep Learning for Volumetric Cone-Beam CT Image Reconstruction

Authors: Ziqi Gao, Lei Xing, Siqi Ye, S. Kevin Zhou

Affiliation: Department of Radiation Oncology, Stanford University, University of Science and Technology of China (USTC)

Abstract Preview: Purpose: To address the challenge of high memory usage in volumetric cone-beam CT (CBCT) imaging, we propose a method that combines joint reconstruction and super-resolution for sparsely sampled CBCT ...

Motion Correction-Driven Patient-Specific 2D Cine MRI-Based Dynamic Volumetric Reconstruction for MRI-Guided Radiotherapy Intra-Fractional Motion Monitoring

Authors: Karyn A Goodman, Yang Lei, Tian Liu, D. Michael Lovelock, Charlotte Elizabeth Read, Jing Wang, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai

Abstract Preview: Purpose: Real-time volumetric MRI is essential for precise motion management in MRI-guided radiotherapy (MRIgRT). While 2D Cine MRI offers high temporal resolution for motion tracking, it inherently l...

Multi-Mechanism CNN and Long Short-Term Memory Fusion Model for Improved CT-Based Thyroid Cancer Diagnosis

Authors: Yunfei Dong, Dongyang Guo, Jiongli Pan, Tao Peng, Caiyin Tang, Zhenyu Yang, Fang-Fang Yin, Lei Zhang, Tianyi Zhang, Yaogong Zhang

Affiliation: Duke Kunshan University, Department of Radiology, Taizhou People’s Hospital Affiliated to Nanjing Medical University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: This study aims to improve the accuracy of CT-based diagnosis of thyroid cancer by developing a hybrid model that integrates Convolutional Neural Networks (CNNs) with Long Short-Term Memory (...

Multi-Scale, Multi-Task Framework with Jacobian Descent for Multi-Plan Dose Prediction in Sequential Boost Radiotherapy

Authors: Steve B. Jiang, Mu-Han Lin, Yu-Chen Lin, Austen Matthew Maniscalco, Dan Nguyen, David Sher, Xinran Zhong

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, UT Dallas

Abstract Preview: Purpose:
Sequential boost radiotherapy (RT) poses a challenge in allocating dose across multiple plans while protecting organs at risk (OARs). Clinicians must decide whether OAR sparing should occu...

Multi-Vendor Validation of a Deep Learning-Based Synthetic CT Generation Model for MR-Only Radiotherapy Planning in the Pelvis

Authors: Gregory Bolard, Rabten Datsang, Sarah Ghandour, Timo Kiljunen, Pauliina Paavilainen, Sami Suilamo, Katlin Tiigi

Affiliation: Turku University Hospital, Virginia Commonwealth University, MVision AI, North Estonia Medical Centre, Docrates Cancer Center, Hopital Riviera-Chablais

Abstract Preview: Purpose: To verify the performance of a vendor-neutral deep learning model for synthetic CT generation from T2-weighted and balanced steady-state MR sequences to support both MR-only simulation and MR...

Neural Implicit K-Space for Accelerated Patient-Specific Non-Cartesian MRI Reconstruction

Authors: Daniel O Connor, Mary Feng, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger, Jess E. Scholey, Ke Sheng, DI Xu, Wensha Yang, Yang Yang

Affiliation: UCSF, University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, University of San Francisco, Department of Radiology, University of California, San Francisco, University of California San Francisco, Siemens Medical Solutions USA Inc.

Abstract Preview: Purpose: The scanning time for a fully sampled MRI is lengthy. Compressed sensing (CS) has been developed to minimize image artifacts in accelerated scans, but the required iterative reconstruction is...

Non-Contact Blood Pressure Estimation Using Remote Photoplethysmography Signals Extracted from Facial Video: A Deep Learning Approach

Authors: Mavlonbek Khomidov, Jong-Ha Lee

Affiliation: Department of Biomedical Engineering, Keimyung University, Department of Computer Engineering, Keimyung University

Abstract Preview: Purpose: In this research, we aim to estimate blood pressure using remote photoplethysmography (rPPG) signal extracted from facial video. This method provides non-invasive and contactless, continuous ...

Pancrea-Seg-Net: A Semi-Supervised Deep Learning Framework for Pancreatic Tumor and Vessel Segmentation

Authors: Manju Liu, Ning Wen, Fuhua Yan, Yanzhao Yang, Zhenyu Yang, Haoran Zhang, Lei Zhang, Yajiao Zhang

Affiliation: Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy where precise segmentation of tumors and adjacent vessels is crucial for effective treatment planning. This study dev...

Patient-Specific Orthogonal Projection Based Real-Time Volumetric X-Ray Imaging for Proton Therapy

Authors: Hao Chen, Kai Ding, Xiaoyu Hu, Xun Jia, Heng Li, Devin Miles

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: Accurately delivering radiation dose is critical in intensity-modulated proton therapy (IMPT), where intrafraction motion management plays a pivotal role. Our proton therapy system equipped x...

Physics and Geometry Input-Based Neural Network Dose Engine

Authors: Ricardo Garcia Santiago, Narges Miri, Daryl P. Nazareth, Ankit Pant, Mukund Seshadri

Affiliation: Roswell Park Comprehensive Cancer Center

Abstract Preview: Purpose: To develop a transformer-based deep learning network framework for predicting VMAT dose distributions. This can provide fast and efficient calculations with accuracies potentially comparable ...

Posterior-Mean Diffusion Model for Realistic PET Image Reconstruction

Authors: Osama R. Mawlawi, Yiran Sun

Affiliation: RICE University, UT MD Anderson Cancer Center

Abstract Preview: Purpose: Conventional PET reconstruction methods often produce noisy images with artifacts due to data/model mismatches and inconsistencies. Recently, deep learning-based conditional denoising diffusi...

Predicting Elective Pelvic Nodal Volumes with Deep Learning: A Tool to Facilitate Peer Review

Authors: Brian M. Anderson, Shiva K. Das, Meagan Foster, Anirudh Karunaker, Lawrence B. Marks, Lukasz Mazur, Michael Repka

Affiliation: UNC Chapel HIll, University of North Carolina at Chapel Hill, UNC School of Medicine, University of North Carolina

Abstract Preview: Purpose: Development of a peer review segmentation check system to identify deviations in physician contours of standard risk pelvic lymph nodes in patients receiving radiation therapy for prostate an...

Real-Time Automatic Treatment Planning System (RT-AutoTPS) for Volumetric Modulated Arc Radiotherapy (VMAT)

Authors: Steve B. Jiang, Austen Matthew Maniscalco, Dan Nguyen, Chenyang Shen, Jiacheng Xie, Shunyu Yan, Ying Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Although treatment planning systems (TPSs) can handle dose calculation and plan optimization automatically, planning for radiotherapy still requires extensive efforts and expertise from a mul...

Real-Time Proton and Carbon Ion Monte Carlo Dose Calculation through GPU-Acceleration and DL-Based Denoising Algorithms

Authors: Yankui Chang, Shijun Li, Xi Pei, Ripeng Wang, Xuanhe Wang, X. George Xu, Qing Zhang, Jingfang Zhao

Affiliation: University of Science and Technology of China, Shanghai proton and heavy ion center, School of Nuclear Science and Technology, University of Science and Technology of China, Anhui Wisdom Technology Co., Ltd.

Abstract Preview: Purpose:
This paper describes disruptive methods using both GPU-based MC simulation and deep-learning (DL)-based MC denoising algorithms, as well as clinical tests involving more than 560 patient p...

SPECT/CT Multimodal Segmentation of Bone Marrow for Theranostic Dosimetry

Authors: Tommaso Frigerio, Joshua Genender, John M. Hoffman, Catherine (Caffi) Meyer

Affiliation: UCLA, David Geffen School of Medicine at UCLA

Abstract Preview: Purpose: Accurate bone marrow segmentation is required for bone marrow dosimetry to monitor for dangers in PSMA-Lu177 radioligand therapy. We introduce a hybrid (AI/semantic knowledge) segmentation pi...

Simulating Realistic Digital Phantoms for Virtual Clinical Trials in Radiology and Radiation Oncology Using a Deep-Learning Based Conditional Denoising Diffusion Probabilistic Model (c-DDPM)

Authors: Matthew Brown, Yushi Chang, Jinhyuk Choi, William Silva Mendes, Lei Ren, Aman Sangal, William Paul Segars, Phuoc Tran, Hualiang Zhong

Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Digital phantoms like XCAT are essential for imaging and treatment optimization in radiology and radiation oncology. However, the lack of realistic textures (HU distribution) in XCAT limits i...

Simultaneous Motion Estimation and Image Reconstruction with Spatiotemporal Implicit Neural Representation Initial (STINR-SMEIR) for Gas Bubble Motion Artifact Reduction in on-Board CBCT Imaging

Authors: Hua-Chieh Shao, Shanshan Tang, Jing Wang, Kai Wang, You Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, University of Maryland Medical Center

Abstract Preview: Purpose: Artifacts caused by gas bubble movement in the gastrointestinal tract can severely degrade the image quality of on-board abdominal cone-beam computed tomography (CBCT), impacting its utility ...

Task-Specific Deep-Neural-Network Architecture Optimization for CBCT Scatter Correction

Authors: Hoyeon Lee

Affiliation: University of Hong Kong

Abstract Preview: Purpose: Deep-learning approaches are widely investigated for Cone-Beam CT (CBCT) scatter correction to improve the quality of the linear-accelerator mounted CBCT. This study aims to optimize the deep...

Ultra-Sparse-View Cone-Beam CT Reconstruction Based Strictly-Structure-Preserved Deep Neural Network in Image-Guided Radiation Therapy

Authors: Guangjun Li, Ying Song, Huanan Tang, Tianxiong Wu, Qiuyi Ye, Wei Zhang

Affiliation: West China Second Hospital of Sichuan University, United Imaging Healthcare, West China Hospital of Sichuan University

Abstract Preview: Purpose:
To propose a general low-dose reconstruction model for ultra-sparse-view cone-beam CT (CBCT) and evaluate its clinical application in improving image quality and reducing radiation dose fo...