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Results for "delivery efficiency": 57 found

A Dosimetric Study of Range-Compensated Proton Arc Therapy

Authors: Alonso N. Gutierrez, Daniel E. Hyer, Blake R. Smith

Affiliation: Miami Cancer Institute, Baptist Health South Florida, Iowa Health Care, University of Iowa

Abstract Preview: Purpose: To perform a feasibility study of optimizing and producing a compact range compensator to deliver single-energy pencil beam scanning (PBS) proton arc therapy treatments. Omitting energy chang...

A Feasible, Extendable, and Low-Cost Web-Based Application to Minimize the Second-Check Workload

Authors: William N. Duggar, Li Yuan

Affiliation: University of Mississippi Medical Center

Abstract Preview: Purpose:
Radiation Oncology departments typically utilize various systems from different vendors. Ensuring the integrity and correctness of data during transfers between these systems is essential ...

A GPU Accelerated Monte Carlo Dose Engine for Small Animal Proton Radiotherapy

Authors: Haonian Gong, Yue Gu, Meiqi Liu, Zihao Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang, Cheng Zheng

Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China

Abstract Preview: Purpose:
Proton radiotherapy in preclinical small animals requires specific dose engine due to its low energy and small irradiation volume. This study is to develop a GPU-based Monte Carlo dose eng...

A Novel Lattice Technique Based Spot Scanning Proton Arc Therapy Via Spot Sparsity Optimization and LET Optimization

Authors: Zhitao Dai, Riao Dao, Xuanfeng Ding, Qingkun Fan, Yajun Jia, Gang Liu, Gang Peng, Yujia Qian, Hong Quan, Kunyu Yang, Sheng Zhang, Lewei Zhao

Affiliation: Department of Radiation Oncology, Stanford University, Corewellhealth William Beaumont University Hospital, School of Mathematics and Statistics, Wuhan University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Chinese Academy of Medical Sciences Cancer Hospital Shenzhen Hospital, School of Physics and Technology,Wuhan University, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

Abstract Preview: Purpose: Lattice radiation therapy (LRT) is an innovative three-dimensional(3D) implementation type of spatially fractionated radiation therapy (SFRT). This study aims to develop a novel spot-scanning...

A Quantitative Analysis of Interplay Effects in IMPT for Lung Cancer SBRT: Comparing Two Machine Delivery Sequence Models

Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Lewei Zhao

Affiliation: Department of Radiation Oncology, Stanford University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital

Abstract Preview: Purpose: This study quantitatively evaluates the interplay effect in intensity-modulated proton therapy (IMPT) for lung cancer stereotactic body radiotherapy (SBRT) using two different machine deliver...

Adapting Newer Treatment Planning Strategy for Uveal Melanoma Cases Using Gamma Knife Radiosurgery

Authors: Deepak Agrawal, Subhash Gupta, Shashanksharad Kale, Gopishankar Natanasabapathi, Manoj Phalak, Dhanabalan Rajasekaran, Surendra Kumar Saini, Subramani Vellaiyan

Affiliation: All India Institute of Medical Sciences (AIIMS), All India Institute of Medical Sciences

Abstract Preview: Purpose:
To evaluate planning strategy for uveal melanoma tumor (UM) in gamma knife stereotactic radiosurgery (GKSRS) using Lightning inverse planning software for treatment planning.
Methods:

An Efficient Workflow for X-Ray Imaging-Based IGRT/ART

Authors: Lili Chen, Ahmed A. Eldib, Chang Ming Charlie Ma

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose: Specialized adaptive radiotherapy (ART) systems have been developed and clinically implemented, which are either cost-ineffective such as MR-linacs or inflexible in workflow such as the Ethos...

An Integrated, Web-Based Tool for Automated Treatment Time Calculations, Data Visualization, and Documentation for Superficial Radiotherapy Using an SRT-100 Vision

Authors: Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Yongsook C. Lee, Michael Leyva, Alejandro Rene Llanes Lopez, Carlos M. Rivera, Ranjini P. Tolakanahalli

Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute, Miami Cancer Institute, Baptist Health

Abstract Preview: Purpose: Accurate treatment time calculation is a critical component of superficial radiotherapy (SRT), particularly for the SRT-100 Vision, where dose delivery depends on applicator geometry, treatme...

Automated Classification of Treatment Sites from Physician Consult Notes Using a Large Language Model

Authors: Klea Hoxha, Dylan P. O'Connell, Ricky R Savjani

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, UCLA Radiation Oncology

Abstract Preview: Purpose: Ambiguities in physician simulation orders lead to workflow disruptions during CT simulation. Often, information that could provide
helpful context to simulation therapists and planners is...

Automated Parametric Custom Collimator Creation for Preclinical Irradiation Studies

Authors: Muhammad Ramish Ashraf, Dixin Chen, Lloyd Emmanuel Kamole Ghomsi, Edward Elliot Graves, Billy W Loo, Stavros Melemenidis, Joseph B. Schulz, Lawrie Skinner

Affiliation: Department of Radiation Oncology, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Precise beam collimation is essential in preclinical radiotherapy studies to ensure accurate dose delivery. Manual design and fabrication of organ-specific collimators usually consist of mult...

Biomechanically Informed Diagnostic-to-Synthetic CT Transformation for Expedited Radiation Therapy Planning

Authors: Liyuan Chen, Steve Jiang, Chenyang Shen

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center

Abstract Preview: Purpose: Delays in radiation therapy (RT) initiation caused by conventional CT simulation processes can hinder timely treatment delivery and patient outcomes. This study proposes a Virtual Treatment S...

Breastplan-Helper: Publicly Shared Source Scripting Toolset to Assist in 3D Breast Planning

Authors: Ryan Clark, Anthony Magliari, Luis Felipe Oliveira E Silva, Yang Sheng, Jason R Vickress, Qingrong Jackie Wu, Giulianne Rivelli Rodrigues Zaratim

Affiliation: Verspeeten Family Cancer Center, Office of Medical Affairs, Varian, A Siemens Healthineers Company, Confiar Radioterapia, Duke University Medical Center

Abstract Preview: Purpose: Develop a toolset to replace several of the tedious steps required to manually generate 3D breast treatment plans using static gantry forward planned tangent beams.

Methods: Eclipse Sc...

Checking of Sensitivity of Volumetric Modulated Arc Therapy Quality Assurance System with a Cavity Generation Method

Authors: Kaile Li, Esmail Parsai

Affiliation: Alexander T. Augusta Military Medical Center, Alexander T. Augusta Miliary Medical Center

Abstract Preview: Purpose: To evaluate the sensitivity of the portal dosimetry system with the Arc CHECK system at identical Volumetric Modulated Arc Therapy (VMAT) setup
Methods: An Arc CHECK system from Sun Nuclea...

Commission and Clinical Implementation of the 1st Step-and-Shoot Proton Arc Therapy for Head and Neck Cancer Patient Treatment

Authors: Xiaoda Cong, Rohan Deraniyagala, Xuanfeng Ding, Xiaoqiang Li, Jian Liang, Peilin Liu, Craig Stevens, Xiangkun Xu, Weili Zheng

Affiliation: Corewell Health William Beaumont University Hospital, Corewellhealth William Beaumont University Hospital, William Beaumont University Hospital, Corewellhealth William Beaumont Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital

Abstract Preview: Purpose:
Commission a step-and-shoot arc therapy(SPArc-step&shoot) for treating head-neck cancer patients as a desired interim milestone toward full dynamic treatment.
Methods:
An in-house de...

Commissioning a Comprehensive Workflow for VMAT Total Body Irradiation (TBI) Using Publicly and Commercially Available Resources

Authors: Alan H. Baydush, Sarah Cummings, Jeffrey Michael Fenoli, Christy Hickerson, Lalith Kumaraswamy, Philmo Oh, Sarah B. Wisnoskie

Affiliation: Novant Health Cancer Institute, Novant Health

Abstract Preview: Purpose: To develop, validate, and commission a VMAT Total Body Irradiation (TBI) workflow by integrating publicly available resources, commercial solutions, and in-house testing to enhance treatment ...

Comparison of Frame-Based and Frameless Gamma Knife Coordinate Spaces for Treatment of Trigeminal Neuralgia

Authors: Tatiana Bejarano, Omer Gal, Alonso N. Gutierrez, Matthew D. Hall, Rupesh Kotecha, Yongsook C. Lee, Michael W. McDermott, Minesh P. Mehta, Robert H. Press, Carlos M. Rivera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek

Affiliation: Miami Cancer Institute, Baptist Health South Florida

Abstract Preview: Purpose:
Gamma Knife (GK) cone beam computed tomography-based stereotactic reference (CBCTRef) combined with pre-planning MRI, provides a flexible alternative to the historical frame-based localiza...

Creation of Customized Workflows in a New Surface-Guided Radiation Therapy (SGRT) System

Authors: Sorour Hosseini, YuHuei Jessica Huang, Jeremy Kunz, Nicholas Pierre Nelson, Ryan G. Price, Prema Rassiah, Hui Zhao

Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah

Abstract Preview: Purpose: To investigate the feasibility and clinical implications of creating customized workflows in a new SGRT system: LUNA 3D (LAP, Florida).
Methods: Three clinical SGRT workflows were designed...

Deep Learning-Based Segmentation for Precision Radiation Therapy in Breast Cancertreatment

Authors: Hamdah Alanazi, Silvia Pella

Affiliation: FAU, Florida Atlantic University

Abstract Preview: Purpose: The appearance of breast cancer in the global list of most common cancers worldwide requires
research for ultimate treatment approaches including radiation therapy to reduce deaths from br...

Design and Testing of an External Control System for Beam Control and Pre-Delivery Optimization for Conventional- and Ultra-High-Dose-per-Pulse Flash Irradiations

Authors: Alexander Baikalov, Luke Connell, Nicholas Coupey, Nolan M. Esplen, Rebecca Lim, Chinh Nguyen, Emil Schueler

Affiliation: Northwell, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: FLASH radiotherapy delivered using electron linear accelerators (LINAC) requires precise control and minimal variation of dose rate and We developed a robust external beam control system (EBC...

Developing and Evaluating the First Pre-Treatment Physics Plan Checklist for Error Detection in Biology-Guided Radiotherapy (BgRT)

Authors: Michael Burke, David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Vanessa Hill, Ann-Teresa Jasman, John Kim, Svetlana Kuznetsova, MinYoung Lee, Daniel Longo, Henry S. Park, Adam Shulman, Lauren Tressel, Weili Zhong

Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose:
The complexity of biology-guided radiotherapy (BgRT), particularly with systems like RefleXion X1, necessitates robust pre-treatment quality assurance (QA) to ensure patient safety, treatm...

Development and Evaluation of Aria Report-Based Initial Chart Check Tool

Authors: Ulrich Langner, Timothy Leech, Oleksii Semeniuk

Affiliation: Brown University Health

Abstract Preview: Purpose: To standardize and improve quality of the chart review process, while simultaneously increasing the efficiency of the physicist, by allowing them to allocate more time for other items.
Met...

Development and Experimental Validation of an in-House Proton Treatment Planning System with Energy Layer Optimization

Authors: Hao Gao, Yuting Lin, Jufri Setianegara, Aoxiang Wang, Peng Xiao, Qingguo Xie, Yanan Zhu

Affiliation: Department of Biomedical Engineering, Huazhong University of Science and Technology, Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: Intensity-modulated proton therapy (IMPT) achieves uniform tumor dose distribution while sparing organs-at-risk (OAR) by optimizing spot weights across energy layers. Accelerating IMPT delive...

Development of a GPU-Based Dose Calculation Engine for MRI-Guided Proton Therapy

Authors: Yaowen Cao, Haonian Gong, Yue Gu, Meiqi Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang, Xiaogang Yuan

Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China

Abstract Preview: Purpose: Magnetic resonance imaging (MRI)-guided proton therapy is an innovative technology that combines superior soft tissue imaging capabilities of MRI with the high dose conformity of proton thera...

Dosimetric Comparison of 6X and 10X Flattening Filter-Free Photon Beams on a Truebeam Linac Using the Eclipse TPS

Authors: Carlos E. Cardenas, Udbhav S. Ram, Marcin Wierzbicki

Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham, Juravinski Cancer Centre

Abstract Preview: Purpose:
This study aims to systematically evaluate the dosimetric properties and delivery efficiency of 6X-FFF and 10X-FFF beams for lung SBRT on the Varian TrueBeam STx using the Eclipse TPS 16.1...

Dosimetric Comparison of MR-Linac Vs. Cyberknife for Prostate Stereotactic Body Radiation Therapy

Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: Prostate stereotactic body radiation therapy (SBRT) requires precise dose delivery to the target volume and organ-at-risk (OAR) sparing. This study compares MR-Linac (MRL) and CyberKnife (CK)...

Dosimetric Variations Induced By Inaccurate Collimator Angles in Single-Isocenter SRS Plan for Multi-Lesion Brain Metastases

Authors: Makunda Aryal, Gregory Bartlett, David D. Campos, Ke Colin Huang, Sook Kien Ng, Christopher F. Njeh, Oluwaseyi Oderinde, Edwin Quashie, Ashok Tiwari, Yong Yue

Affiliation: Purdue University, Department of Radiation Oncology, Indiana University, Indiana University, Indiana University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose:
Linear accelerator-based single-isocenter Stereotactic Radiosurgery (SRS) is widely used for treating brain metastases due to its efficiency, reduced treatment time, and lower imaging dose...

Dual-Domain Reconstruction Network for Nonstop Gated CBCT Imaging: Application in Respiratory Gating Ablative Radiotherapy for Pancreatic Cancer

Authors: Sean L. Berry, Weixing Cai, Laura I. Cervino, Yabo Fu, Daphna Gelblum, Wendy B. Harris, Xiuxiu He, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Boris Mueller, Huiqiao Xie, Mitchell Yu, Hao Zhang

Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Gating ablative radiotherapy for pancreatic cancer accounts for tumor movement due to respiration and typically requires 5, 15, or 25 fractions. Pretreatment imaging verification is essential...

Evaluating the Efficacy and Efficiency of Spine Treatment Using Diagnostic CT

Authors: Sunil Mani, Ilakiya Raghavendiran, Vasanthan Sakthivel, Skanda Kabilan Swamy

Affiliation: Edmond Santa Fe High School, Edmnd Deer Creek High, Cancer Specialists of North Florida, Advanced Medical Physics

Abstract Preview: Purpose: Purpose/Objective(s): To evaluate and validate the dose calculation and delivery accuracy for patients planned using diagnostic CT
Methods: A total of forty-two patients with palliative sp...

Evaluation of Hybrid Dynamic Conformal Arc Planning for SRS and SBRT Treatment

Authors: Pat Esposito, Ashley Klein, Carmine Verna, Ling Zhuang

Affiliation: Northwestern Medicine

Abstract Preview: Purpose: To evaluate dosimetric parameters and treatment delivery efficiency between volumetric modulated arc therapy (VMAT) and hybrid dynamic conformal arc (HDCA) on SRS and SBRT planning through st...

Evaluation of Plan Quality and Optimal Isocenter Arrangement for Total Marrow and Lymphoid Irradiation on a Ring-Gantry Linac with Dual-Layer Mlc Using the Knowledge-Based Planning Technique

Authors: Chunhui Han, An Liu, Anthony Magliari, Lesley Rosa

Affiliation: Office of Medical Affairs, Varian, A Siemens Healthineers Company, Department of Radiation Oncology, City of Hope National Medical Center

Abstract Preview: Purpose: To evaluate the performance of a knowledge-based planning (KBP) optimization model for total marrow and lymphoid irradiation (TMLI) on a ring-gantry linac with a dual-layer MLC and to evaluat...

Evaluation of Treatment Delivery Efficiency and Workflow Optimization in Prostate Stereotactic Body Radiation Therapy: A Comparative Study of C-Arm and O-Ring Linear Accelerators

Authors: Yijian Cao, Jenghwa Chang, Lyu Huang

Affiliation: Northwell, Hofstra University Medical Physics Program

Abstract Preview: Purpose: This study evaluates the treatment delivery efficiency and workflow of two advanced linear accelerator systems—Varian’s TrueBeam (C-arm) and Halcyon (O-ring)—for prostate Stereotactic Body Ra...

Exploring the Compatibility of VMAT and Respiratory Beam Gating on MR-Linac: A Proof-of-Concept Study

Authors: Caiden Atienza, Pim T. S. Borman, Martin F. Fast, Daniel E. Hyer, Bas W. Raaymakers, Jeffrey E. Snyder, Prescilla Uijtewaal, Peter Woodhead

Affiliation: Department of Radiotherapy, University Medical Center Utrecht, Yale New Haven Health, University of Iowa

Abstract Preview: Purpose:
On conventional C-arm linacs, VMAT is the preferred delivery modality due to its superior efficiency and highly conformal dose distributions. MR-linacs offer superior soft-tissue imaging t...

Feasibility Study of Single Gantry Angle Proton Minibeam Lattice Radiotherapy

Authors: Anthony Hong Cheol Lim, Rayyan L Mahmood, Alexander Stanforth, Chris C. Wang, Mingyao Zhu

Affiliation: Georgia Institute of Technology, Emory University

Abstract Preview: Purpose: The purpose of this project is to test the feasibility of proton minibeam lattice radiotherapy within an existing clinical setting.
Methods:
The TOPAS code is used to model a scenario i...

Feasibility of Rapidarc Dynamic for Lattice Radiation Therapy of Bulky Liver Tumors

Authors: Christine V. Chung, Laurence Edward Court, Meena S. Khan, Ethan B. Ludmir, Rachael M. Martin Paulpeter, Saurabh Shashikumar Nair, Callistus M. Nguyen, Joshua S. Niedzielski, Luis Augusto Perles

Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Spatially Fractionated Radiation Therapy (SFRT) has re-emerged as an efficacious treatment approach for bulky solid tumors. RapidArc Dynamic (RAD) has unique beam delivery capabilities that m...

GPU-Accelerated Beamlet and Full Dose Calculations for Efficient Radiation Therapy Planning

Authors: Girish Bal, Jan Kralj, Ayan Mitra, PhD, Ling Shao, Matjaz Subic, Yevgen Voronenko

Affiliation: RefleXion Medical, Cosylab

Abstract Preview: Purpose: This work enhances the efficiency of radiation therapy treatment planning by optimizing the beamlet dose matrix and full patient dose computations using GPU acceleration. The Collapsed-Cone C...

High-Fidelity Treatment Optimization for Online Adaptive Stereotactic Partial Breast Irradiation: Integrating Dose and Treatment Time Considerations

Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Courtney Bosse Stanley, Dennis N. Stanley, Sean Xavier Sullivan, Natalie N. Viscariello

Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, University of Alabama at Birmingham

Abstract Preview: Purpose: CBCT-guided online adaptive radiation therapy (OART) with Ethos for stereotactic accelerated partial breast irradiation (APBI) can mitigate inter-fraction variation, leading to dosimetric adv...

Hypersight® Offline Adaptive Workflow

Authors: Doris Dimitriadis/Dimitriadou, Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Noor Mail, Adam Olson, Tyler Wilhite

Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, UPMC

Abstract Preview: Purpose: The goal of the HyperSight® offline adaptive-workflow is to create a methodical approach to adaptive-radiotherapy (ART) that considers modifications in patient setup and anatomy. Through effi...

Image-Guided Adaptive Proton Therapy for Head and Neck Cancer Using a Novel Gantry-Less System

Authors: Philip Blumenfeld, Jon Feldman, Yair Hillman, Michael Marash, Aron Popovtzer, Alexander Pryanichnikov, Shimshon Winograd, Marc Wygoda, Vered Zivan

Affiliation: Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), P-Cure Ltd./Inc., Sharett Institute of Oncology, Hadassah Medical Center, Hebrew University of Jerusalem

Abstract Preview: Purpose:
Image-guided adaptive proton therapy (IGAPT) allows tailored dose adjustments to account for anatomical and physiological changes during treatment. Recent efforts have developed a cost-eff...

Introduce a Novel Spot-Scanning Proton Arc(SPArc) Optimization Algorithm for Single Energy Extraction(SEE) Synchrotron-Accelerator-Based Proton Therapy System (PTS)

Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Jiajian Shen

Affiliation: Department of Radiation Oncology, Mayo Clinic, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital

Abstract Preview: Purpose: This study aims to develop the first SPArc optimization algorithm based on the Dynamic Programming (SPArc-DP), to improve the treatment delivery efficiency for synchrotron-accelerator-based P...

Investigating Pitch Factor on Plan Quality in Patients Treated with Hippocampal Avoidance Whole Brain Radiotherapy Using Volo Ultra-Optimized Helical Tomotherapy Plans

Authors: Awens Alphonse, Nebi Demez, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Gagandeep Saini, Nishan Shrestha, Somol Sunny

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: This study examined the impact of varying the pitch factor in hippocampal-avoidance whole-brain (HP-WB) radiotherapy treatments, utilizing the newly introduced VOLO Ultra optimization for Hel...

Investigating the Dosimetric Benefits of Enhanced Solid Angle Accessibility in a Self-Shielded Radiosurgery System

Authors: Peter Jermain, Ying Niu, Abdul Rashid, Yuan Yuan, Mohammad Zarenia

Affiliation: Medstar Georgetown University Hospital, MedStar Georgetown University Hospital, Department of Radiation Medicine, MedStar Georgetown University Hospital

Abstract Preview: Purpose: ZAP-X is a self-shielded radiosurgery system that utilizes a linac-based isocentric technique and a compact gyroscopic gantry design. While it provides a large solid angle for beam orientatio...

Mid-Range Planning for Efficient and Robust Proton Arc Therapy

Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Zi Yang, Kangning Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Delivery efficiency and robustness are critical in spot-scanning proton arc therapy (SPAT), yet the conventional use of redundant energy layers (ELs) prolongs switching times and reduces effi...

Multi-Sid Optimization for 4 Pi Robotic Radiotherapy

Authors: Qihui Lyu, Dan Ruan, Ke Sheng, Jingjie Yu

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose: The robotic arm radiotherapy platform enables flexible delivery of non-coplanar and non-isocentric radiotherapy with variable Source-to-Isocenter Distances (SIDs). However, the high degrees o...

Optimized Dosimetric Planning for Trigeminal Neuralgia Using Cyberknife S7 Precision TPS with Volo Optimizer

Authors: Amy Fitzpatrick, Kim Howard, Julius G. Ojwang, Neelu Soni

Affiliation: Mercy Hospital Springfield

Abstract Preview: Purpose: This study evaluates the dosimetric advantages and workflow improvements of the CyberKnife S7 Precision Treatment Planning System (TPS) with the VOLO optimizer for stereotactic radiosurgery (...

Optimizing Minimum Monitor Unit Thresholds for Proton Breast Therapy on the Iba Proteusone

Authors: Chia-Lung Chien, Wen C. Hsi, Faraz Kalantari, Pouya Sabouri, Man Yam

Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)

Abstract Preview: Purpose:
Reducing treatment delivery time is critical to improving patient throughput and minimizing the risk of intrafraction motion, which can compromise treatment accuracy. This study identifies...

Optimizing Timing of Physics Consults for Proton Prostate Therapy: Improving Patient Experience and Operational Efficiency

Authors: Charles D. Bloch, Stephen R. Bowen, Bing-Hao Chiang, Alex Egan, Eric C. Ford, Sharareh Koufigar, Dominic A. Maes, Juergen Meyer, Sharon Pai, Frank Rafie, Rajesh Regmi, Jatinder Saini, George A. Sandison, Marco Schwarz, Bishwambhar Sengupta, Tony P. Wong

Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Physics, University of Washington

Abstract Preview: Purpose: This study aimed to optimize the strategy and timing of physics consults for proton prostate patients to improve the patient experience and resource utilization in our radiation oncology depa...

Predicting CBCT-Based Adaptive Radiation Therapy Session Duration Using Machine Learning

Authors: Leslie Harrell, Sanjay Maraboyina, Romy Megahed, Maida Ranjbar, Xenia Ray, Pouya Sabouri

Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), University of California San Diego

Abstract Preview: Purpose: Real-time adaptive radiation therapy (ART) dynamically modifies patients’ treatment plan during delivery to account for anatomical and physiological variations. Addressing ART planning time v...

Presenting a Novel Treatment Scheme for Debulking Unresectable Large Tumors: Feasibility, Safety and Patient Reported Early Clinical Outcomes of SBRT Immediately Post-Spatially Fractionated Radiotherapy Delivery

Authors: James Knight II, Joshua Misa, Damodar Pokhrel, William St Clair, Eddy S Yang

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine

Abstract Preview: Purpose: Highly-heterogenous sieve-like dose distribution via SFRT to large/bulky tumors (≥6 cm) could enhance tumor cell-death via both direct/indirect cell-kill mechanisms. Adding highly-conformal S...

Python-Based Patient Coaching System for Gated Treatment Delivery

Authors: Usha Robins Abraham, Monique Lockhart Chisem, Alonso N. Gutierrez, Janos Juhasz, Michael Leyva, Carlos M. Rivera, Ranjini P. Tolakanahalli, Vanessa Vega Fleites

Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute, Miami Cancer Institute, Baptist Health

Abstract Preview: Purpose:
Accurate breath hold (BH) gated treatments rely heavily on patient cooperation. Maintaining consistent breath-hold levels can be challenging for patients. Surface image guidance (SGRT) is ...

Real-Time 3D Dose Verification for MR-Guided Online Adaptive Radiotherapy (ART) Via Geometry-Encoded Deep Learning Framework

Authors: Steve B. Jiang, Dan Nguyen, Chenyang Shen, Fan-Chi F. Su, Jiacheng Xie, Shunyu Yan, Daniel Yang, Ying Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Fast dose verification is essential for the safety and efficiency of MR-guided adaptive radiotherapy (ART) as patients anxiously waiting on the treatment couch. Conventional tools often requi...

Rectangular Aperture-Based Beam Orientation Optimization for 4π Non-Coplanar Small Animal IMRT Delivery

Authors: Dante PI Capaldi, Lu Jiang, Qihui Lyu, Ke Sheng

Affiliation: Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose:
Preclinical small animal studies help understand radiation-induced biological responses, toxicities, and mechanisms, facilitating the translation of new therapies to patient treatment. Int...

Small but Mighty: A Lightweight and Computationally Efficient Model for Deformable Image Registration

Authors: Hengjie Liu, Dan Ruan, Ke Sheng, DI Xu

Affiliation: Physics and Biology in Medicine, University of California, Los Angeles, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, Los Angeles

Abstract Preview: Purpose:
State-of-the-art deep learning-based deformable image registration often uses large, complex models directly adapted from computer vision tasks but achieves only comparable performance to ...

Standardized MRI-CT Hybrid Workflow for High-Dose-Rate Image-Guided Adaptive Brachytherapy in Cervical Cancer: Aapm TG-303 Implementation

Authors: Kim Creach, Kim Howard, Julius G. Ojwang, Richard A. Shaw, Neelu Soni

Affiliation: Mercy Hospital Springfield

Abstract Preview: Purpose: To present a standardized MRI-CT hybrid workflow for High-Dose-Rate (HDR) Image-Guided Adaptive Brachytherapy (IGBT) in cervical cancer, aligned with AAPM TG-303, as a model to assist with im...

The Feasibility of Ethos-Based Pulsed Reduced Dose-Rate (PRDR) Radiotherapy

Authors: Chia-Lung Chien, Renteng Hou, Wen C. Hsi, Faraz Kalantari, Ganesh Narayanasamy, Zhong Su

Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)

Abstract Preview: Purpose:
PRDR is an effective re-irradiation treatment for patients who have already reached the tolerance dose to their organs at risk (OARs). While PRDR is implemented on TrueBeam by limiting the...

Treatment Plan Comparisons of Head and Neck Cancers on Varian Ethos/Halcyon and Truebeam Linac

Authors: Yunfeng Cui, Joseph P. Kowalski, Qiuwen Wu, Yibo Xie

Affiliation: Duke University, Duke University Medical Center

Abstract Preview: Purpose: A Varian Ethos/Halcyon linac was recently commissioned in our clinic and was used to treat head and neck cancer patients. The purpose of this study is to compare treatment plan quality and de...

Unlocking Adaptive Radiotherapy Flexibility: Integrating Ethos Adaptive Therapy and Halcyon IGRT with Scripting Innovations

Authors: Min Geon Choi, Sean J. Domal, Ruiqi Li, Taoran Li, Mu-Han Lin, Yang Kyun Park, David D.M. Parsons, Justin D. Visak

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, University of Pennsylvania, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Ethos X-ray-guided online adaptive radiotherapy (ART) enables precise, daily adaptive treatments but requires significant resources, limiting widespread adoption. Many treatment sites do not ...

Workflow for Same Day Linac-Based Stereotactic Radiosurgery

Authors: William Amestoy, Carolina Benjamin, Markus Bredel, Rodrigo Delgadillo, Nesrin Dogan, Michael E Ivan, Ricardo J Komotar, Gregory J. Kubicek, Eric Mellon, Ivaylo B. Mihaylov, Maria Irene Monterroso, Raymond A. Schulz, Ashish Shah, Robert M Starke

Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center, Varian Medical Systems

Abstract Preview: Purpose: Stereotactic Radiosurgery (SRS) is a widely used treatment modality in radiation oncology, utilizing various technologies such as Gamma Knife (GK), Cyber Knife (CK) and Linac-based SRS with H...