Authors: Adayabalam Balajee, Elijah Berberette, Maria Escalona, Dray Gentry, Chester R. Ramsey, Terri Ryan
Affiliation: ORAU, Thompson Proton Center, University of Tennessee
Abstract Preview: Purpose:
Dicentric chromosomes, characterized by two centromeres on a single chromosome, are key biomarkers in biological dosimetry for quantifying ionizing radiation exposure. However, manual dete...
Authors: Michael Cuddy, Samuel J. Fahrenholtz, Khushnood Hamdani, Saman Jirjes, Robert G. Paden, Jeremiah W. Sanders, William F. Sensakovic, Wolfgang Stefan, Jeffrey Xiao, Yuxiang Zhou
Affiliation: Mayo, Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Title: An automated system for MRI coil performance evaluation
Purpose: To develop an automated quality control (QC) system for MRI coils to assess element-level signal-to-noise ratio (SNR), ar...
Authors: Beth Bradshaw Ghavidel, Benyamin Khajetash, Yang Lei, Meysam Tavakoli
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Emory University, Department of Radiation Oncology, Emory University
Abstract Preview: Purpose: Pancreatic cancer is among the most aggressive types of cancer, with a five-year survival rate of approximately 10%. Recent studies show that radiomics and deep learning (DL)-based methods ar...
Authors: Steven Brown, Mike Hopkins, Jerimy C. Polf, Scott Sawyer, Benjamin L. Viglianti
Affiliation: H3D, inc, University of Michigan, M3D, Inc, M3D Imaging
Abstract Preview: Purpose: We characterized the sensitivity, energy dependence, and calibrated dose rate for a radiation imaging survey meter (RAVIN Cam; M3d inc., Ann Arbor MI) based on cadmium zinc telluride (CZT) cr...
Authors: Md Mainul Abrar, Harsh Arya, Yujie Chi, Yijing Liu, Joshua Rajan, Pan Zui
Affiliation: University of Texas at Arlington, The University of Texas at Arlington, Department of Physics, University of Texas at Arlington
Abstract Preview: Purpose: Understanding the biological effects of alpha radiation at varying dose rates and energies is essential for advancing therapeutic strategies. This study demonstrates the capabilities of an in...
Authors: Casey E. Bojechko, Lance C Moore
Affiliation: University of California, San Diego, University of California San Diego
Abstract Preview: Purpose: EPID images collected during treatment can serve as an in-vivo error detection mechanism. Previous works have shown that comparing in-vivo EPID images to AI-predicted EPID images for IMRT pla...
Authors: Robert H Hadfield, Madelyn Johnson, Baozhu Lu, Hongjing Sun, Vikas Vikas, Brian C. Wilson, Weibing Yang, Timothy C. Zhu
Affiliation: University of Glasgow, University of Toronto, University of Pennsylvania
Abstract Preview: Purpose:
Multispectral Singlet Oxygen Luminescent Dosimetry (MSOLD) has been developed as a real-time in vivo dosimetry technique for Photodynamic Therapy (PDT). This study investigates the feasibi...
Authors: Soo Hyun Byun, Troy Farncombe, Edcer Jerecho DC Laguda
Affiliation: McMaster University
Abstract Preview: Purpose: We present the adaptation of a Cadmium Zinc Telluride (CdZnTe) detector, initially designed for SPECT-MR applications, to neutron imaging. This study explores a novel technique that utilizes ...
Authors: Theresa Busch, Robert H Hadfield, Madelyn Johnson, Baozhu Lu, Hongjing Sun, Brian C. Wilson, Weibing Yang, Timothy C. Zhu
Affiliation: University of Glasgow, University of Toronto, University of Pennsylvania
Abstract Preview: Purpose: Direct detection of singlet-state oxygen (¹O₂) is crucial for advancing type II photodynamic therapy (PDT), but its short lifetime makes in vivo measurement highly challenging. Although Photo...
Authors: Thomas R. Bortfeld, Prof. Elisabetta De Bernardi, Tianxue Du, Beatrice Foglia, Chiara Gianoli, Takamitsu Masuda, Katia Parodi, Marco Pinto, Boon-Keng Kevin Teo, Yunhe Xie
Affiliation: Department Of Radiation Oncology, Massachusetts General Hospital (MGH), School of Medicine and Surgery, University of Milano-Bicocca, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, National Institutes for Quantum Science and Technology (QST), University of Pennsylvania, Department of Experimental Physics - Medical Physics, Ludwig-Maximilians-Universität (LMU) München
Abstract Preview: Purpose: The full potential offered by protons in clinical practice is limited by range uncertainties. One possibility for monitoring is through secondary prompt gammas (PG). PG emission along the pen...
Authors: Nan Li, Yaoying Liu, Shouping Xu, Xinlei Xu, Gaolong Zhang
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, School of physics, Beihang University, Beihang University, Department of Radiation Oncology
Abstract Preview: Purpose:
CT simulation is essential for radiation therapy preparation but has limitations in distinguishing lesions. Contrast-enhanced CT (CECT) improves lesion detection and characterization, but ...
Authors: Sarah Burleson, Antonio L. Damato, Yabo Fu, Laura Happersett, Tianfang Li, Xiang Li, Himanshu Nagar, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: An iodinated hydrogel perirectal spacer, injected between the prostate and rectum, reduces rectal high-dose exposure during prostate SBRT. We assessed the feasibility of tracking the spacer a...
Authors: Christopher Bartee, Justin Riley DeFrancisco, Marcos Feijoo, Siyong Kim, Tianjun Ma
Affiliation: Blue Physics LLC, Virginia Commonwealth University
Abstract Preview: Purpose: Irradiation with FLASH has been shown to decrease normal tissue toxicity while maintaining similar tumor control. To advance FLASH into the clinic, more preclinical investigations are first n...
Authors: Shatha Al Afifi, Hana Baroudi, Leonard Che Fru, Laurence Edward Court, Suzanne B. Evans, Kent A. Gifford, Adam D. Melancon, Melissa P. Mitchell, Issa Mohamad, Patricia Murina, Manickam Muruganandham, Tucker J. Netherton, Callistus M. Nguyen, Joshua S. Niedzielski, Deborah L. Schofield, Simona Shaitelman, Willie Shaw, Sanjay S. Shete, Adam Shulman, Brendon Smith, Sheeba Thengumpallil, Carlos Daniel Venencia, Conny Vrieling
Affiliation: University of Cape Town, MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, University of the Free State, UT MD Anderson Cancer Center, King Hussein Cancer Center, Instituto Zunino - Fundacion Marie Curie, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Dra., Hirslanden Clinique des Grangettes, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Therapeutic Radiology, Yale University School of Medicine, Yale University, The University of Texas, MD Anderson, Houston TX
Abstract Preview: Purpose:
Automated contouring and planning tools are usually trained on single-institution datasets, seldom tested across diverse patient populations. This introduces a risk of population bias, res...
Authors: Maria Jose Almada, Oscar Apaza, Carlos Bohorquez, Ezequiel Cabrera, Rogelio Diaz Moreno, Maximiliano Musso, Rosa Petit, Carlos Daniel Venencia, Lucy D. Wolfsberger
Affiliation: LAP, FaMAF, UNC, Instituto Zunino - Fundacion Marie Curie
Abstract Preview: Purpose:
PSQA employs gamma analysis to verify the planned versus delivered dose. Evaluating the effectiveness of PSQA techniques in identifying errors is crucial. This study aims to incorporate ML...
Authors: Maya Ataya, Clint Bahler, Ramotallah Dami Jubril, Michael Koch, Oluwaseyi Oderinde, Mark Tann
Affiliation: Purdue University, epartment of Urology, Indiana University School of Medicine, Department of Urology, Indiana University School of Medicine, Department of Radiology and Imaging Sciences, Indiana University School of Medicine
Abstract Preview: Purpose:
To investigate racial differences in the detection of biochemical recurrence (BCR) using 68Ga-PSMA-11 PET/CT, known for its improved sensitivity and specificity in patients after radical p...
Authors: Yuqi Yang, Fang-Fang Yin
Affiliation: Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Reactive oxygen species (ROS) are unstable molecules which play important roles in the cellular process after Flash radiotherapy. The rapid changes in ROS levels during treatment may provide ...
Authors: Amar K. Basavatia, Lee C. Goddard, Wolfgang A. Tomé, Christian Velten, Ping Yan, Ravindra Yaparpalvi, Maria Stefania diMayorca
Affiliation: Montefiore Medical Center
Abstract Preview: Purpose: High dose rate (HDR) brachytherapy planning is a high-risk procedure performed under significant time pressure, with human failure being the leading cause of error. To elevate training for me...
Authors: Curtiland Deville, Rachel B. Ger, Heng Li, Todd R. McNutt
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Proton therapy patients receive quality assurance CT scans (QACTs) during treatment to verify dosimetric accuracy and determine adaptive therapy needs as proton treatments are highly sensitiv...
Authors: Marcos Feijoo, Mamoru Ichiki, Tatsuya Maeda, Tatsuhiro Makino, Tomonori Megumi, Tadashi Nakabayashi, Yukino Nakata, Shuichi Ozawa, Daishi Takayama
Affiliation: Hiroshima High-Precision Radiotherapy Cancer Center, Blue Physics LLC, Imamura General Hospital, Accuray Inc.
Abstract Preview: Purpose: This study aims to accurately measure the leaf open time (LOT) of the multi-leaf collimator (MLC) in tomotherapy using an advanced plastic scintillator detector (PSD) with high time resolutio...
Authors: Go Akamatsu, Han Gyu Kang, Chie Seki, Hitomi Sudo, Hideaki Tashima, Chie Toramatsu, Hidekatsu Wakizaka, Iwao Yamaya, Taiga Yamaya
Affiliation: National Institutes for Quantum Science and Technology
Abstract Preview: Purpose:
Tumor oxygen status, which provides important information to optimize particle therapy, may constantly change during a treatment period of several weeks. However, it is impractical to perf...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
This work demonstrates how existing software, when creatively adapted, can address a wide range of clinical challenges. By focusing on data exploration and application-specific modificatio...
Authors: Angela J Da Silva, Andrew Groll, Gopinath Kuduvalli, Thomas Laurence, David W. Meer, Manoj Narayanan, Mingshan Sun, Don Vernekohl, Ray Yang
Affiliation: RefleXion Medical
Abstract Preview: Purpose: To implement post-treatment review of delivered dose fractions on RefleXion X1 accounting for independent detection of transmitted beamlets and transient dose fluctuations of individual pulse...
Authors: Fred B. Bateman, Ilaria M. Luna, Ronald E. Tosh
Affiliation: Sidwell Friends School, NIST, Dosimetry Group, Radiation Physics Division, National Institute of Standards and Technology
Abstract Preview: Purpose: To exploit the rapid response time and dose sensitivity of ultrasonic detection methods for resolving pulse structure in FLASH-level beams.
Methods: Two ultrasonic transducers position...
Authors: Petr Bruza, Megan Clark, David J. Gladstone, Lesley A Jarvis, Allison Matous
Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health
Abstract Preview: Purpose: In vivo dosimetry (IVD) is underutilized, in part, because measured point doses cannot be accurately localized to the patient or treatment planning system (TPS), complicating the clinical and...