Authors: Brett Bocian, Nesrin Dogan, John C. Ford, Alan Pollack, Ryder Marshall Schmidt, Junwei Shi, Jorge D Vega
Affiliation: University of Miami, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: X-ray fluorescence computed tomography (XFCT) is an emerging molecular imaging modality gaining attention in cancer theranostics with high-Z metal nanoparticles (MNPs). While XFCT has been de...
Authors: Fu-Xiong Chang, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Nancy Y Lee, Chih-Hsun Lin, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Pingfang Tsai, Shouyi Wei, Irini Yacoub, Yunjie Yang, Ajay Zheng, Jun Zhou
Affiliation: New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Liverage Biomedical Inc., Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Institute of Physics, Academia Sinica
Abstract Preview: Purpose: FLASH therapy presents an opportunity to alter the radiotherapy paradigm and significantly enhancing normal organ protection while maintaining the effectiveness of tumor control. The temporal...
Authors: John J. DeMarco, Farideh Pak, Olivia Grahm C Valadie
Affiliation: Cedars Sinai, Cedars-Sinai, Cedars-Sinai Medical Center
Abstract Preview: Purpose: To investigate the performance of the Integral Quality Monitor (IQM) device for patient-specific QA, focusing on segment-by-segment signal evaluation compared to cumulative signal evaluation....
Authors: John Bennet, Indrin J. Chetty, Tai H. Dou
Affiliation: Department of Radiation Oncology,Cedars Sinai Medical Center, Department of Radiation Oncology, Cedars Sinai Medical Center, Department of Radiation Oncology,Cedars-Sinai Medical Center
Abstract Preview: Purpose:
To investigate the effect of complexity of stereotactic radiosurgery (SRS) volumetric modulated arc therapy plans on gamma pass rates (GPR) using a novel high-resolution ion chamber array ...
Authors: Emily Hansen, Tyler Kaulfers, Alois M. Ndlovu, Francia Romero, Niara Rowe, Roland Teboh
Affiliation: Montefiore Einstein University Hospital, Hackensack University Medical Center
Abstract Preview: Purpose: Daily use and reliance on the auto registration feature requires a performance check. Clinical application of auto registration is performed without a selected region of interest (ROI), requi...
Authors: Yuemeng Feng, Hamid Sabet
Affiliation: Massachusetts General Hospital, Harvard Medical School
Abstract Preview: Purpose: We propose a novel brain-dedicated PET system comprising elliptical cylinder with a neck cut-out, supplemented by front and back panels to improve sensitivity and line-of-response sampling. T...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski, Huanyi Zhou
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose: A new CT configuration utilizing a multiple X-ray-source array (MXA) is under development to mitigate cone-beam (CB) artifacts in single-rotation wide coverage imaging. We investigate the sam...
Authors: Dylan Yamabe Breitkreutz, Lee Chin, Brige P. Chugh, Mark D'Souza, Brian M. Keller, Anthony Kim, Michelle K. Nielsen, Arjun Sahgal
Affiliation: Sunnybrook Health Sciences Centre
Abstract Preview: Purpose: The Elekta Unity MR-linac delivers highly conformal SBRT treatments using IMRT. These treatment plans require patient-specific quality assurance (PSQA) measurements to detect discrepancies be...
Authors: Milad BaradaranGhahfarokhi, Manuel A. Morales Paliza
Affiliation: Vanderbilt University Medical Center
Abstract Preview: Purpose: The purpose of this study was to commission Varian HDR surface applicators using a high-resolution diode array and film dosimetry. This work evaluates dosimetric characteristics of these appl...
Authors: Michalis Aristophanous, Steven Blum, Laura I. Cervino, Antonio L. Damato, Karen Episcopia, Chi Huang, Shih-Chi Lin, Michelle K. Savacool
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Varian Ethos (Varian Medical Systems, Palo Alto, CA) is a 6 MV flattening-filter-free (FFF) only machine, posing a challenge in creating homogeneous dose distributions when using manual 3D-CR...
Authors: Wenwen Bai
Affiliation: The Fourth Hospital of Hebei Medical University
Abstract Preview: Purpose: To compare three kind of solutions (EDR2 Film, MatriXX, COMPASS) for VMA quality assurance at head and Neck in Monaco plannig system.
Methods: Monacao 5.1 planning system optimazed 10 case...
Authors: Go Akamatsu, Yuma Iwao, Kurumi Narita, Hideaki Tashima, Taiga Yamaya, Eiji Yoshida
Affiliation: National Institutes for Quantum Science and Technology
Abstract Preview: Purpose: In brain positron emission tomography (PET), higher spatial resolution is better for visualizing detailed structures such as small nuclei and the layered structure of the cerebral cortex. The...
Authors: Wesley E. Bolch, Lotem Buchbinder Shadur, Natalia Estefania Carrasco-Rojas, Chansoo Choi, Robert Joseph Dawson, Shaheen Dewji, John Francis, Emmanual Mate-Kole, Wyatt Smither, Yitian Wang
Affiliation: Georgia Tech, University of Florida, Nuclear and Radiological Engineering and Medical Physics Programs, Georgia Institute of Technology
Abstract Preview: Purpose: Develop a software application capable of assessing the radiation contamination of military service members and members of the general public for fast, on-site radiological triage. The softwa...
Authors: Soo Hyun Byun, Troy Farncombe, Edcer Jerecho DC Laguda
Affiliation: McMaster University
Abstract Preview: Purpose: We present the adaptation of a Cadmium Zinc Telluride (CdZnTe) detector, initially designed for SPECT-MR applications, to neutron imaging. This study explores a novel technique that utilizes ...
Authors: John M. Boone, Andrew M. Hernandez, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski
Affiliation: Johns Hopkins University, University of California, UT MD Anderson Cancer Center, University of New Mexico Albuquerque, UC Davis Health
Abstract Preview: Purpose: To significantly improve image quality relative to clinically deployed digital breast tomosynthesis (DBT) systems, which use a 1D acquisition geometry (an arc), with a 2D image acquisition ge...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski, Huanyi Zhou
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose: A Multiple-X-ray Source Array (MXA) for CT (MXA-CT) is under development to mitigate cone beam artifacts in axial CT scans using wide collimation. The purpose of this study is to assess the i...
Authors: Wesley S. Culberson, Ryan Gardner, Patrick M Hill, Mark Pankuch, Karsten K. Wake
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Wisconsin, Northwestern Medicine Proton Center
Abstract Preview: Purpose: To assess the dosimetric capabilities of Sun Nuclear (Melbourne, FL) EDGE Diode Detectors™ for measurements in the plateau region of pencil beam scanning (PBS) fields. Many clinical dosimeter...
Authors: Enzo Charles Aucca, Roger Challco, Andres M. Gonzales Galvez, Carmen SANDRA Guzman Calcina, Jimmy Hernandez-Bello, Modesto Montoya, Renzo Aaron Ocampo, Erick Paniagua, Miguel Alberto Risco-Castillo, Dante E. Roa, Renzo E. Romero, William Souza Santos, Mirko Salomón Alva Sánchez
Affiliation: Graduate Program in Information Technologies and Health Management, University of Porto AlegreFederal University of Health Sciences of Porto Alegre, Universidad Tecnologica del Peru, Pontificia Universidad Catolica del Peru, Electronic Engineering Department, Leonard Cancer Institute - Radiation Oncology, Universidad Nacional de Ingenieria, Universidad Nacional de Ingenieria, Electronic Engineering Department, Federal University of Sergipe, HRS Oncology International, Universidad Nacional Federico Villareal
Abstract Preview: Purpose: Provide Monte Carlo (MC) and experimental dosimetric assessments of a 3D cubic electronic detector array based on percent depth doses (PDDs), profiles, linearity, and dose rate response of ph...
Authors: Nobukazu Fuwa, Masato Horita, Takahiro Kato, Ryo Tanokura, Yuki Tominaga
Affiliation: Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Central Japan International Medical Center, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University
Abstract Preview: Purpose:
We have installed a new type of scanned proton therapy system (Varian ProBeam 360°TM). This study aimed to evaluate the four different dose calculation algorithms.
Methods:
Sixteen b...
Authors: Sabrina Campelo, Sandun Y. Jayarathna, Adam D. Melancon, Paige L. Nitsch, Christopher Ryan Peeler, Julianne M. Pollard-Larkin, Ramaswamy Sadagopan, Xiaochun Wang, George Zhao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Development of an in-house analytical simulation for streamlining photon counting detector (PCD) system protocols through measuring transmitted photon energy spectra through a Hafnium (Hf)-lo...
Authors: Grace Hutchinson, Daniel E. Hyer, Samuel D. Rusu, Blake R. Smith, Joel J. St-Aubin
Affiliation: Iowa Health Care, University of Iowa
Abstract Preview: Purpose: To assess the feasibility and consistency of the Sun Nuclear Corporation (SNC) MR conditional Quad Wedge, as an accessory to the IC Profiler-MR, and to evaluate beam output and energy in the ...
Authors: Davide Brivio, Lia Carroll, Juliane Daartz, Jan PO Schuemann, Piotr Zygmanski
Affiliation: Massachusetts General Hospital, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: We employ High-Energy Current (HEC) detectors for real-time monitoring of proton beams at conventional to FLASH dose rates. This would help overcome the need for fast and accurate dosimeters ...
Authors: Xun Jia, Heng Li, Wen Li, Devin Miles, Daniel Sforza, Lingshu Yin, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: FLASH therapy holds great potential to revolutionize radiotherapy by minimizing toxicities of normal tissues. The extraordinarily high dose rate of FLASH proton beam makes precise delivery to...
Authors: Saree Alnaghy, Owen Thomas Dillon, Sean P Hood, Paul J. Keall, Ricky O'Brien, Tess Reynolds
Affiliation: Image X Institute, Faculty of Medicine and Health, The University of Sydney, University of Wollongong, Medical Radiations, School of Health and Biomedical Sciences, RMIT University
Abstract Preview: Purpose: Photon Counting Detectors (PCDs) have been demonstrated to improve resolution, contrast and lesion detectability in fan-beam CT. There is naturally a desire to bring these improvements to Con...
Authors: Sang Hyun Cho, Sandun Y. Jayarathna, Neerajan Nepal
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: To develop/validate a Monte Carlo (MC) model of an experimental benchtop x-ray fluorescence computed tomography (XFCT) system with a pixelated CdTe detector that can be used for MC simulation...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Sarah E. McKenney, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose:
While wide coverage (160 mm) CT scanners can image whole organs (e.g. heart, brain, kidneys, etc.) in one axial scan, the peripheral regions of the field of view (along z) suffer from cons...
Authors: Hulya Ozdemir Buss, Jeffrey Geiger, Kim Howard, Julius G. Ojwang, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: The Radixact Synchrony system integrates real-time motion tracking and compensates to improve treatment accuracy for moving targets. This study presents a streamlined and efficient quality as...
Authors: Muhammad Ramish Ashraf, Clinton Gibson, Gregory Szalkowski, Lei Wang, Siqi Wang, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University
Abstract Preview: Purpose: To develop a neural network-based super-resolution framework for enhancing the resolution of sparse dosimetry measurements in patient-specific radiotherapy QA. Sparse detector arrays, such as...
Authors: Salahuddin Ahmad, Imad M. Ali, Zaid Alkalani, Nesreen Alsbou
Affiliation: University of Oklahoma, University of Central Oklahoma, University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: To design and evaluate a 3D-detector for proton CT-imaging and radiography, utilizing volumetric plastic scintillator detector exposed to high-energy therapeutic beams from proton therapy sys...
Authors: Guang-Pei Chen, Renae Conlin, Juan A. Garcia-Alvarez, Kirk Morris, Haidy G. Nasief, Eenas A. Omari, Eric S. Paulson
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Cumulative dose limits make replacing and calibrating Metal Oxide Semiconductor Field Effect dosimeters (MOSFET-d) used for in-vivo dosimetry a common clinical task. Calibration protocols for...
Authors: Ryan Burri, Nazanin Hoshyar, Jerry W. McCoy, Yulin Song, Huma Syed
Affiliation: Bay Pines VA Medical Center
Abstract Preview: Purpose: The study aimed to streamline traditionally manual, iterative, and time-consuming VMAT commissioning process. The goal was to identify an optimal set of MLC dosimetric parameters that minimiz...