Authors: Gary Y. Ge, Charles Mike Weaver, Jie Zhang
Affiliation: University of Kentucky
Abstract Preview: Purpose: The recently introduced CMS regulation on CT dose and image quality mandates the use of global noise as the metric for image quality assessment. The regulation cites two methods for calculati...
Authors: Huay Din, Grace Jianan Gang, Grace Hyun Kim, Michael F. McNitt-Gray, Joseph W. Stayman, Yijie Yuan
Affiliation: Johns Hopkins University, John Hopkins University, University of Pennsylvania, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose:
Radiomics rely on quantitative features to discern underlying biological signatures. However, feature dependence on the imaging systems themselves hampers the creation of reproducible and ...
Authors: Nina Burbure, Tawfik Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital, Dept. of Radiation Oncology, Fox Chase Cancer Center at Temple University Hospital
Abstract Preview: Purpose: Higher rates of local failures and toxicities challenged radiation therapy of centrally located lung cancer (CLLC). We assessed the treatment response by measuring the early changes of PET+ n...
Authors: Benjamin R. Awad, Bulent Aydogan, Howard J Halpern, Erik Pearson, Gage H. Redler, Jordan M. Slagowski, Rajit Tummala, Autumn E. Walter-Denzin, Jimmy Zydlo
Affiliation: University of Wisconsin-Madison Department of Human Oncology, University of Oxford, The University of Chicago, Moffitt Cancer Center, California State University, Fresno, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Small animal models are crucial in cancer research to develop, validate, and translate basic scientific hypotheses into clinical advancements. This study aims to make small animal intensity-m...
Authors: Dale Black, David Clymer, Huanjun Ding, Hamidreza Khodajou Chokami, Sabee Molloi, Christine Vy Nguyen, Tim Sananikone, Alireza Shojazadeh, Randy Wang
Affiliation: Department of Radiological Sciences, University of California, University of California, Department of Radiological Sciences, University of California, Irvine, Department of Radiological Sciences, University of California, Irvine
Abstract Preview: Purpose: We present a novel multi-material decomposition (MMD) algorithm for accurate quantification of material concentration in reconstructed dual-energy CT images. This method addresses limitations...
Authors: Jaryd Ricardo Christie, Anthony J. Doemer, William T. Hrinivich, Junghoon Lee, Calin Reamy, Kundan S Thind
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, Henry Ford Health
Abstract Preview: Purpose: To develop and validate an open-source Python package for fast, widely compatible, and user-friendly photon dose calculation algorithm through comparisons with clinical treatment planning sys...
Authors: Zhiqiang Chen, Hewei Gao, Li Zhang, Guoxi Zhu
Affiliation: Tsinghua University
Abstract Preview: Purpose: Spectral cone-beam CT has better performance in material identification and quantitative analysis compared to single-energy cone-beam CT. However, X-ray scattering introduces significant scat...
Authors: Cheewai Cheng, Indra J. Das, Jeffrey Yui Hei Wong, Poonam Yadav
Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine
Abstract Preview: Purpose: Radiation treatment machine replacement brings chaos and urgency of timely completion of machine commissioning for every procedure used including TBI that are time consuming. Based on past ex...
Authors: Santosh K. Agarwalla, Nrusingh C. Biswal, Shree C, Harikrishnan Suresh Kumar, Jajati K. Nayak, Prema P., Sarath K S, Tamil Selvan S, Hem D. Shukla
Affiliation: Variable Energy Cyclotron Centre, Department of Physics, Fakir Mohan University, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Sciences, Amrita Vishwa Vidyapeetham
Abstract Preview: Purpose: The rapid oxygen depletion in tissues during irradiation is the most accepted mechanism of the FLASH effect. However, the Normal Tissue Complication Probability (NTCP) and Tumor Control Proba...
Authors: Richard Lesieur, Olivia Magneson, David E. Solis, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: This study evaluates the deliverability and precision of multileaf collimator (MLC) positioning in treatment plans generated by two different Treatment Planning Systems (TPS), Monaco and Pinn...
Authors: Mateb Ali Alghamwa, Haya Aljuaid, Siyong Kim, Tianjun Ma, William Song
Affiliation: Virginia Commonwealth University
Abstract Preview: Purpose: The integration of Plastic Scintillation Detectors (PSDs) into 0.35T MR-Linac systems represents a significant advancement in radiotherapy, offering substantial benefits due to their tissue-e...
Authors: Brian Burger, Carri K. Glide-Hurst, John W. Hayes, Carson Hoffman, Minglei Kang, Jessica R. Miller, Jordan M. Slagowski, Yuhao Yan
Affiliation: Department of Human Oncology, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Leo Cancer Care
Abstract Preview: Purpose: The combination of upright CT and patient positioner for particle therapy present tremendous potential for high precision IGRT and online adaptive radiation therapy (ART), where reliable CT p...
Authors: David L. Barbee, Paulina E. Galavis, Lena Adel Samad, Jose R. Teruel Antolin
Affiliation: NYU, NYU Langone Health
Abstract Preview: Purpose: To validate an automated script that converts treatment plans of varying Varian MLC models
Methods: A C# script was developed using the Eclipse Scripting API to convert treatment plans...
Authors: Maria Jose Almada, Carlos Bohorquez, Maximiliano Musso, Rosa Petit, Carlos Daniel Venencia, Lucy D. Wolfsberger
Affiliation: LAP, Instituto Zunino - Fundacion Marie Curie
Abstract Preview: Purpose:
PSQA is crucial in maintaining patient safety, typically depending on dosimetric measurements. However, advancements in computational technology have highlighted the growing significance o...
Authors: Shupeng Chen, Xiaoda Cong, Raymond Dalfsen, Rohan Deraniyagala, Xuanfeng Ding, James E. Dolan, Xiaoqiang Li, Jian Liang, Peilin Liu, An Qin, Martin Soukup, Craig Stevens, Xiangkun Xu, Weili Zheng
Affiliation: Corewell Health William Beaumont University Hospital, Corewellhealth William Beaumont University Hospital, William Beaumont University Hospital, Elekta, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Corewellhealth William Beaumont Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital
Abstract Preview: Purpose: To facilitate clinical use of the proton feature of Monaco treatment planning system(TPS), we commissioned and validated it on a compact proton therapy system.
Methods: Pencil Beam Scannin...
Authors: Milad BaradaranGhahfarokhi, Manuel A. Morales Paliza
Affiliation: Vanderbilt University Medical Center
Abstract Preview: Purpose: The purpose of this study was to commission Varian HDR surface applicators using a high-resolution diode array and film dosimetry. This work evaluates dosimetric characteristics of these appl...
Authors: Serdar Charyyev, Cynthia Fu-Yu Chuang, Veng Jean Heng, Lianli Liu, Lei Xing, Yong Yang
Affiliation: Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose: To replace large finite-size photon phase space files with a compact neural network capable of generating an infinite number of particles.
Methods: Three separate models were developed to ...
Authors: Sarah Aubert, Harald Keller, Jeff D. Winter
Affiliation: Princess Margaret Cancer Centre
Abstract Preview: Purpose: Support for treatment planning directly on CBCT imaging on C-arm linacs will enable adaptive radiation therapy (ART) capacity with increased treatment technique flexibility. The HyperSight im...
Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: To assess the dependency of CT numbers on position in the field-of-view (FOV) using single-energy (SE) and dual-energy (DE) images and energy-integrating detector (EID) and photon-counting de...
Authors: Clifford Ghee Ann Chua, Calvin Wei Yang Koh, Kah Seng Lew, Zubin Master, Sung Yong Park, Hong Qi Tan, Andrew Wibawa
Affiliation: National Cancer Centre Singapore
Abstract Preview: Purpose: To investigate the impact of spot position deviation on reference dosimetry measurements using different delivery patterns and to determine the optimal delivery pattern for reference dosimetr...
Authors: Wesley E. Bolch, Lotem Buchbinder Shadur, Natalia Estefania Carrasco-Rojas, Chansoo Choi, Robert Joseph Dawson, Shaheen Dewji, John Francis, Emmanual Mate-Kole, Wyatt Smither, Yitian Wang
Affiliation: Georgia Tech, University of Florida, Nuclear and Radiological Engineering and Medical Physics Programs, Georgia Institute of Technology
Abstract Preview: Purpose: Develop a software application capable of assessing the radiation contamination of military service members and members of the general public for fast, on-site radiological triage. The softwa...
Authors: Bhuvaneswari Narayanan, Niko Papanikolaou, Daniel L. Saenz
Affiliation: UT Health San Antonio, University of Texas HSC San Antonio
Abstract Preview: Purpose: To evaluate dosimetric accuracy of Brainlab Elements (BLE) 4.0 treatment planning system (TPS) for linac based SRS and Spine SBRT treatment.
Methods: RT Safe cranial and thorax phantoms wi...
Authors: Kazi Towmim Afrin, Imad M. Ali, Jordan West
Affiliation: University of Oklahoma Health Sciences Center, University of Oklahoma
Abstract Preview: Purpose: To evaluate quantitatively the dosimetric uncertainties associated with dose calculation and measurement of small photon fields used in stereotactic photon therapy.
Methods: The output fac...
Authors: Matthew Stephen Andriotty, Chi Ma, Xiao Wang, Keying (Karen) Xu, Suhong Yu, Ning J. Yue, Yin Zhang
Affiliation: Brigham and Women's Hospital, Rutgers Cancer Institute of New Jersey
Abstract Preview: Purpose: To evaluate the effects of overlapping CT reconstruction on dosimetry calculation for LINAC-based SRS patients simulated on CT simulators from three different vendors.
Methods: CT simulati...
Authors: Zakaria Aboulbanine, Greeshma A. Agasthya, Paul Inman, Anuj J. Kapadia, Anthony Hong Cheol Lim, Jayasai Ram Rajagopal, Chris C. Wang
Affiliation: Oak Ridge National Laboratory, Georgia Institute of Technology
Abstract Preview: Purpose: Radiobiological simulation via TOPAS-nBio requires significant computational resources and time to provide meaningful results. This study aims to decrease simulation time and computational re...
Authors: Darwin Abraham Garcia, Michael P. Grams, Scott C Lester, Maryam Mashayekhi, Douglas John Moseley, Robert W Mutter, Sean S Park, Chrystian Quintero Mateus
Affiliation: Mayo Clinic - Rochester, Mayo Clinic
Abstract Preview: Purpose: MBRT delivers sub-millimeter wide regions of high “peak” (~10s Gy) and low “valley” (~1 Gy) doses to treat cancer. MBRT commissioning is performed in flat, uniform plastic water. Thus, differ...
Authors: Nobukazu Fuwa, Masato Horita, Takahiro Kato, Ryo Tanokura, Yuki Tominaga
Affiliation: Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Central Japan International Medical Center, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University
Abstract Preview: Purpose:
We have installed a new type of scanned proton therapy system (Varian ProBeam 360°TM). This study aimed to evaluate the four different dose calculation algorithms.
Methods:
Sixteen b...
Authors: Chloe DiTusa, Panayiotis Mavroidis, Christopher W. Schneider, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center, University of North Carolina
Abstract Preview: Purpose: To evaluate and compare dose calculation differences between Monaco and AdaptBox by TheraPanacea on AI-generated pseudo-CTs (pCTs) from a CBCT.
Methods: Dose calculations in water phan...
Authors: Yunzhi Ma, Ling Zhuang
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: Multiple layers of brass mesh bolus (RPD, Inc., Albertville, MN) may be needed to provide better body conformity and sufficient dose build up on patient surface during electron treatment. Thi...
Authors: Bing-Hao Chiang, Eric C. Ford, Juergen Meyer, Timothy D. Solberg
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: This study evaluated the potential risk reduction of various pretreatment patient-specific quality assurance (PSQA) programs for Intensity Modulated Radiation Therapy (IMRT) in mitigating fai...
Authors: Matthew R. Hoerner, Maryam Naseri, Mena Shenouda
Affiliation: Yale University School of Medicine, Yale University
Abstract Preview: Purpose:
Historically film has been the gold standard receptor for measurements of x-ray tube focal spot size. Flat Panel Digital Radiography Detectors (FPDRDs) have lower spatial resolution compar...
Authors: Wesley E. Bolch, Chansoo Choi, Chan Hyeong Kim, Suhyeon Kim, Bangho Shin, Yeon Soo Yeom
Affiliation: Hanyang University, University of Florida, 2) Department of Radiation Convergence Engineering, Yonsei University
Abstract Preview: Purpose: Task Group 103 of International Commission on Radiological Protection (ICRP) recently released new-generation adult and pediatric mesh-type reference computational phantoms (MRCPs) via ICRP P...
Authors: Max Chen, Sean Marquardt, Ben Yang, Kai Yang
Affiliation: Cary Academy, Massachusetts General Hospital, Winchester High School
Abstract Preview: Purpose: To analyze the impact of scanner model variation on the effective dose conversion factor (“k-factor”), which is most commonly used for CT effective dose calculation.
Methods: The stand...
Authors: Michael Ashenafi, Nicholas Becerra Espinosa, Mario Ramos Gallardo, Matthew Pacella, Sean M. Tanny
Affiliation: Department of Radiation Oncology, University of Rochester
Abstract Preview: Purpose: A new multileaf collimator (MLC) model has been introduced in Varian Eclipse v18.0, with the treatment planning system (TPS) explicitly modeling the leaf end effects. The vendor recommends a ...
Authors: Hajee Reyaz Ali Sahib, Sangeeta Hazarika, Muthukumaran Manavalan, Jaswin Raj, Daya Nand Sharma, Seema Sharma, Subramani Vellaiyan
Affiliation: AIIMS NCI Jhajjar, PTW North America Corporation, All India Institute of Medical Sciences
Abstract Preview: Purpose:
Purpose is to investigate the effect of extended source-to-imager distances (SID) on the resolution of VMAT patient-specific quality assurance (PSQA) in portal dosimetry (PD).
Methods:<...
Authors: Takahiro Kato, Teiji Nishio, Masataka Oita, Robabeh Rahimi, Yuki Tominaga, Yushi Wakisaka
Affiliation: University of Maryland, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University, Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Medical Physics Laboratory, Division of Health Science, Osaka University Graduate School of Medicine, Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
Abstract Preview: Purpose: This study evaluated dose verifications and lateral penumbra improvements for scanned proton therapy plans with and without a multi-leaf collimator (MLC) under various air gaps.
Methods: E...
Authors: Alexander Alsalihi, Gary Y. Ge, Charles Mike Weaver, Jie Zhang
Affiliation: University of Kentucky
Abstract Preview: Purpose: The upcoming CMS regulation, titled “Excessive Radiation Dose or Inadequate Image Quality for Diagnostic Computed Tomography (CT) in Adults”, employs two measures, size-adjusted DLP (SAD) and...
Authors: Salim Balik, Nguyen Phuong Dang, Hualin Zhang
Affiliation: Radiation Oncology, Keck School of Medicine of USC
Abstract Preview: Purpose: An accurate and convenient monitoring of radiation dose delivery during treatment is essential for ensuring patient safety and treatment efficacy. This project aims to develop innovative algo...
Authors: Bin Cai, Andrew R. Godley, Brian A. Hrycushko, Heejung Kim, Mu-han Lin, David D.M. Parsons, Justin D. Visak, Da Wang, Tingliang Zhuang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: The standard radiation therapy workflow requires CT-simulation and planning, whether for initial treatments or re-planning due to significant anatomical changes. IPART instead uses one patien...
Authors: John P. Aris, Wesley E. Bolch, Chansoo Choi, Carlos G. Colon-Ortiz, Robert Joseph Dawson, Abdul-Vehab Dozic, Amy M. Geyer, Harald Paganetti, Shreya P. Pathak, Julia D. Withrow
Affiliation: St. Luke's Health System, Massachusetts General Hospital, University of Florida
Abstract Preview: Purpose: The goal of this study was to enhance the accuracy of renal dosimetry in radiopharmaceutical therapy (RPT) by developing a more detailed and precise kidney model. In RPT, accurate dose estima...
Authors: Robert A. Dahl
Affiliation: Mayo Foundation
Abstract Preview: Purpose: To develop tools to simplify/accelerate the quality assurance testing of the Mobetron mobile linear accelerator and increase safety when moving it to different OR’s.
Methods: The Mobet...
Authors: Estelle Batin, Michael A. Carlson, Nilendu Gupta, Zachary X. Richards, Diana Shvydka
Affiliation: Department of Radiation Oncology, The Ohio State University Wexner Medical Center
Abstract Preview: Purpose: With an increase in world-wide proton treatment availability, patients sometimes are transferred between proton and photon modalities. Among the main reasons for modality shifts are proton be...
Authors: Stephen M Corner, Daiki Hara, Jiasen Ma, Robert W Mutter, Mark D. Pepin, Nicholas B. Remmes, Hok Seum Wan Chan Tseung
Affiliation: Mayo Clinic - Rochester
Abstract Preview: Purpose: Proton minibeam radiotherapy (pMBRT) is a form of spatially fractionated radiation therapy leveraging submillimeter beams to improve the therapeutic ratio. We report on collimator design, com...
Authors: Em Harkness, Francesco Ria, Ehsan Samei
Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose:
A recently introduced mathematical method quantifies performance-based clinical risk to create a risk-to-risk assessment with radiation risk, rendering the so-called total risk. However, t...
Authors: Chloe DiTusa, Panayiotis Mavroidis, Christopher W. Schneider, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center, University of North Carolina
Abstract Preview: Purpose:
To calculate radiobiological metrics of daily dose delivered for head and neck (HN) patients using the daily cone beam CT (CBCT) to generate a pseudo CT (pCT). Moreover, this work compares...
Authors: Steve B. Jiang, Austen Matthew Maniscalco, Dan Nguyen, Chenyang Shen, Jiacheng Xie, Shunyu Yan, Ying Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Although treatment planning systems (TPSs) can handle dose calculation and plan optimization automatically, planning for radiotherapy still requires extensive efforts and expertise from a mul...
Authors: Austen N. Curcuru, Winter Green, Yao Hao, Jiayi Liu, Yuting Peng, Tiezhi Zhang, Xiandong Zhao
Affiliation: Washington University School of Medicine, Department of Radiation Oncology, WashU Medicine, Virginia Commonwealth University, Washington University School of Medicine, Washington University in St. Louis
Abstract Preview: Purpose: We proposed a treatment planning optimization method that utilizes customized spot map modification to achieve less dosimetry uncertainty, monitor unit ratio (MUR) and neutron dose in a spot ...
Authors: Curtiland Deville, Rachel B. Ger, Elaina Hales, Heng Li, Todd R. McNutt
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Lack of specialized coding knowledge limits the use of data from large SQL repositories. We aimed to develop intuitive user interfaces for a registry that allows users to visualize the relati...
Authors: Sean P. Devan, Cory S. Knill, Choonik Lee, Claire Zhang
Affiliation: University of Michigan, Department of Radiation Oncology, University of Michigan
Abstract Preview: Purpose: Tools such as step-by-step instructions, checklists, and automated calculations can improve process efficiency, mitigate errors, and facilitate standardization across different users and clin...
Authors: Kevin Peter Risolo
Affiliation: University of Pennsylvania
Abstract Preview: Purpose: To quantify the improved efficiency of checking patient treatment plan MU by utilizing RadFormation’s ClearCalc script-based program.
Methods: A total of 58 patients planned for treatment ...
Authors: Michael Armstrong, Courtney R. Buckey, Quan Chen, Suzanne J. Chungbin, Mirek Fatyga, Yi Rong, Jun Tan, Xiang Sheng Yan
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: To model a commercial rotational table in treatment planning system (TPS) for accurate dose optimization and calculation.
Methods: A commercial rotational table (CDR Equilibrium®) is r...
Authors: Ryan Burri, Nazanin Hoshyar, Jerry W. McCoy, Yulin Song, Huma Syed
Affiliation: Bay Pines VA Medical Center
Abstract Preview: Purpose: The study aimed to streamline traditionally manual, iterative, and time-consuming VMAT commissioning process. The goal was to identify an optimal set of MLC dosimetric parameters that minimiz...
Authors: Sagine Berry-Tony, Lasya Daggumati, James R Duncan, Melak Senay, Allan Thomas
Affiliation: University of Missouri-Kansas City School of Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine, Washington University in St. Louis
Abstract Preview: Purpose: Most acquired images in FGIs are not permanently archived. In the context of modern computational prowess, novel improvements to FGI practice likely sit just under the surface of large-scale ...
Authors: Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, Tae Ho Kim, Sangmin Lee
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: The CyberKnife system, designed for stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), considers SRS MapCHECK an effective tool for patient-specific QA (PSQA). This wo...
Authors: Michael Evan Chaga, Timothy Chen, Shabbar Danish, Jesse Feng, Joseph Hanley, Georg A. Weidlich
Affiliation: Zap Surgical, Tenafly High School, Jersey Shore University Medical Center
Abstract Preview: Purpose: ZapMU is the first independent monitor unit check software freely available supporting ZAP-X. In this study, the validation of ZapMU for independent check of dose calculation is performed, ut...