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Results for "digital twin": 11 found

Comparison of AI-Based and Ants for Longitudinal Deformable Image Registration in Head and Neck Cancer

Authors: Aditya P. Apte, Joseph O. Deasy, Jue Jiang, Nancy Lee, Sudharsan Madhavan, Nishant Nadkarni, Lopamudra Nayak, Harini Veeraraghavan, Wei Zhao

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: To track early response to radiotherapy using digital twins, it is crucial to quantify tumor volume and mass changes. Traditional tumor detection methods, particularly in image registration, ...

Developing digital twins to integrate the predicted physical and radiobiological response into routine radiotherapy: a roadmap

Authors: Joseph O. Deasy

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: N/A...

Digital Twins for Precision Oncology: from Concepts to Clinical Implementation

Authors: Jun Deng

Affiliation: Yale University School of Medicine

Abstract Preview: N/A...

Exploring the Potential of Digital Twins for Online Adaptive Radiotherapy

Authors: Xiaofeng Yang

Affiliation: Emory University

Abstract Preview: N/A...

Feasibility Study on Creating a Digital Twin of Digital Subtraction Angiography Data Utilizing Monte Carlo and Computational Fluid Dynamic Simulations

Authors: Ciprian N. Ionita, Parisa Naghdi, Ahmad Rahmatpour

Affiliation: University at Buffalo, SUNY: University at Buffalo

Abstract Preview: Purpose: Quantitative angiography (QA) evaluates neurovascular hemodynamics, but is affected by X-ray parameters, vessel foreshortening, and imaging chain factors like detector efficiency, pixel size,...

Generation of Patient-Specific Phantom for Head & Neck Proton Therapy Based on Xcat

Authors: Cheng-En Hsieh, Shen-Hao Li, Hsin-Hon Lin, Shu-Wei Wu, An-Ci Yang

Affiliation: Department of Medical Imaging and Radiological Sciences, Chang Gung University, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital Linkou

Abstract Preview: Purpose:
The aim of this study is to develop a framework of generating patient-specific phantom tailored for head and neck proton therapy. From these phantoms, digital reference objects based on th...

In-Silico Clinical Trials Enabled By Digital Twin Approach Can Accurately and Prospectively Predict Outcomes of Clinical Trials Combining Radiation and Systemic Therapy

Authors: Clemens Grassberger, David (Bo) McClatchy, Harald Paganetti

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Massachusetts General Hospital

Abstract Preview: Purpose: While randomized controlled trials (RCTs) are the gold standard for demonstrating efficacy, nearly 50% of late-stage clinical trials fail to meet their endpoint. Tools to study the design of ...

Patient-Specific Imaging Modality Agnostic Virtual Digital Twins Modeling Temporally Varying Digestive Motion

Authors: James M. Balter, Lando S. Bosma, Jorge Tapias Gomez, Nishant Nadkarni, Mert R Sanbuncu, William Paul Segars, Ergys D. Subashi, Neelam Tyagi, Harini Veeraraghavan

Affiliation: University of Michigan, The University of Texas MD Anderson Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Cornell University, University Medical Center Utrecht, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Develop patient-specific virtual digital twin (VDT) cohorts modeling physically realistic spatio-temporal gastrointestinal (GI) organs (stomach and duodenum) digestive motion.
Methods: Pat...

Physics-Informed Neural Network for In Vivo Dosimetry during Proton Therapy Using Protoacoustic Tomography

Authors: Kristina Bjegovic, Yong Chen, Gilberto Gonzalez, Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu

Affiliation: University of Maryland School of Medicine, University of California, Irvine, University of Oklahoma Health Sciences Center, University of Oklahoma Health Science Center

Abstract Preview: Purpose: Proton therapy is becoming an increasingly popular choice for cancer treatment due to its precision, reduced side effects, and effectiveness. While dosimetry is fundamental to the success of ...

Predicting and Monitoring Response to Head and Neck Cancer Radiotherapy Using Multi-Modality Imaging and Radiobiological Digital Twin Simulations

Authors: Eric Aliotta, Michalis Aristophanous, Joseph O. Deasy, Bill Diplas, Milan Grkovski, James Han, Vaios Hatzoglou, Jeho Jeong, Nancy Y Lee, Ramesh Paudyal, Nadeem Riaz, Heiko Schoder, Amita Shukla-Dave

Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: To forecast radiotherapy treatment response for head and neck cancer (HNC) using multimodality imaging and personalized radiobiological modeling.
Methods: Multi-modality imaging data from ...

Quantifying Uncertainties in Radiation Risk and Performance-Based Clinical Risk Assessment in Clinical Computed Tomography

Authors: Em Harkness, Francesco Ria, Ehsan Samei

Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose:
A recently introduced mathematical method quantifies performance-based clinical risk to create a risk-to-risk assessment with radiation risk, rendering the so-called total risk. However, t...