Authors: Timothy J Allen, David A. Sterling
Affiliation: University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: Treatment planning for the Venezia HDR brachytherapy applicator is often performed using inverse planning tools such as IPSA or HIPO. However, there are planners who are either unfamiliar wit...
Authors: Jenghwa Chang, Marissa Joyce Vaccarelli
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose: AAPM Report 365 recommends medical physics graduate programs offer courses covering mathematical/statistical methods (section 3.1.7) as well as computational methods/medical informatics (sect...
Authors: Christopher L. Deufel, Suman Gautam, William Y. Song
Affiliation: Virginia Commonwealth University, Mayo Clinic
Abstract Preview: Purpose: Direction modulated brachytherapy creates anisotropic dose distribution from an isotropic source. This study aims to develop a truncated conditional value at risk optimization algorithm for D...
Authors: Sahaja Acharya, Matthew Ladra, Junghoon Lee, Lina Mekki, Bohua Wan
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University, Department of Computer Science, Johns Hopkins University
Abstract Preview: Purpose: Cerebellar mutism syndrome (CMS) is the most frequently observed complication in children undergoing surgical resection of posterior fossa tumors. Previous work explored lesion to symptom map...
Authors: Dylan Yamabe Breitkreutz, Lee Chin, Brige P. Chugh, Mark D'Souza, Brian M. Keller, Anthony Kim, Michelle K. Nielsen, Arjun Sahgal
Affiliation: Sunnybrook Health Sciences Centre
Abstract Preview: Purpose: The Elekta Unity MR-linac delivers highly conformal SBRT treatments using IMRT. These treatment plans require patient-specific quality assurance (PSQA) measurements to detect discrepancies be...
Authors: Gourav Jhanwar, Mojtaba Tefagh, Masoud Zarepisheh
Affiliation: The University of Edinburgh, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
Radiotherapy treatment planning involves solving computationally-intensive and time-consuming optimization problems. Central to these problems is a large matrix known as the dose-influence...
Authors: Tsuicheng D. Chiu, Weiguo Lu, Aaron Thomlinson, You Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose: To develop and validate an MR-compatible anthropomorphic motion phantom to assess liver motion, real-time dosimetry, and gating system performance under controlled and reproducible respirator...
Authors: Guang-Pei Chen, Mi Huang, Haidy G. Nasief, Eric S. Paulson
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Recently, kV imaging has been integrated into the Accuray Radixact platform, facilitating online adaptive and scan-plan-treat workflows with helical delivery in the near future. In order to s...
Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...
Authors: Carlos E. Cardenas, Udbhav S. Ram, Marcin Wierzbicki
Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham, Juravinski Cancer Centre
Abstract Preview: Purpose:
This study aims to systematically evaluate the dosimetric properties and delivery efficiency of 6X-FFF and 10X-FFF beams for lung SBRT on the Varian TrueBeam STx using the Eclipse TPS 16.1...
Authors: Kathryn J. Dess, Martha M. Matuszak, Dan Polan
Affiliation: University of Michigan
Abstract Preview: Purpose: A recent survey demonstrated 18 of 20 top academic institutions have implemented auto-segmentation. Studies to date have focused on geometric contour changes and dosimetric differences using ...
Authors: Deidre Batchelar, Michael Kudla, Stephanie Merkl, Tony Teke
Affiliation: BC Cancer - Kelowna
Abstract Preview: Purpose: Preplanning 3D-printed templates for cervical and vaginal brachytherapy is an iterative process, often taking hours to for an individual patient.
This study demonstrates an end-to-end auto...
Authors: Diana Cardona, Casey C. Heirman, William Jeck, Kyle J. Lafata, Xiang Li, Lauren M. Neldner, Jeffrey S. Nelson, Megan K. Russ, Ehsan Samei
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Pathology, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: Medical physicists have traditionally supported radiation-based medicine, but their expertise can translate to other image-based fields including pathology. As pathology transitions to digita...
Authors: Ciprian N. Ionita, Parisa Naghdi, Ahmad Rahmatpour
Affiliation: University at Buffalo, SUNY: University at Buffalo
Abstract Preview: Purpose: Quantitative angiography (QA) evaluates neurovascular hemodynamics, but is affected by X-ray parameters, vessel foreshortening, and imaging chain factors like detector efficiency, pixel size,...
Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens
Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI
Abstract Preview: Purpose:
It has been challenging to acquire clinically useful MR images of pediatric cancer patients without anesthesia, and MR contrast agents. Custom-made immobilization devices and optimization ...
Authors: Jason Chiang, Magnus Dahlbom, Veronica Hankil, Xinyi Li, Catherine (Caffi) Meyer, Kyung Hyun Sung
Affiliation: UCLA, University of California, Los Angeles
Abstract Preview: Purpose:
Yttrium-90 (90Y) radioembolization is a well-established therapy for large or multifocal liver tumors. Accurate dosimetry is critical but remains challenging, as low particle density risks...
Authors: Bryan Bednarz, John M. Floberg, Joseph B. Schulz, Jordan M. Slagowski
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Catheter placement for high-dose-rate brachytherapy (HDR BT) is clinician dependent and potentially suboptimal for delivering simultaneous integrated boosts to intraprostatic gross tumor volu...
Authors: Shen Fu, Zhangmin LI, Zuofeng LI, Yuanshui Zheng
Affiliation: GuangZhou Concord Cancer Center, Guangzhou Concord Cancer Center
Abstract Preview: Purpose: To investigate the influence of different robustness optimization strategies and parameters in proton therapy plans for head and neck tumors on target coverage and OAR (organ at risk) sparing...
Authors: J. Daniel Bourland, Christina K Cramer, Justin M. Napolitano, James D. Ververs
Affiliation: Wake Forest University School of Medicine
Abstract Preview: Purpose:
Brain metastases (BM) can be treated with linear accelerator (LINAC)-based stereotactic radiosurgery (SRS). Treatment planning for this modality has evolved over time; treatment plans typi...
Authors: Joseph A. Moore, Paul Rothweiler, Jussi K. Sillanpaa, Adhvaith Sridhar
Affiliation: University of Minnesota
Abstract Preview: Purpose: To investigate 3D printed human tissue simulant phantoms for use in radiation therapy and to quantify the mechanical and radiation properties of these phantoms.
Methods: We designed and 3D...
Authors: Martin Frank, Oliver Jäkel, Niklas Wahl
Affiliation: Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Karlsruhe Institute of Technology (KIT)
Abstract Preview: Purpose: Machine learning (ML) models on normal tissue complication and tumor control probability ((N)TCP) exploiting e.g. dosiomic and radiomic features are playing an increasingly important role in ...
Authors: Ibtisam Almajnooni, Victor Cobilean, Milos Manic, Harindra Sandun Mavikumbure, Elisabeth Weiss, Lulin Yuan
Affiliation: Virginia Commonwealth University
Abstract Preview: Purpose: This study aims to optimize the 3D U-Net architecture for dose prediction in lung cancer radiation therapy (RT) plans, particularly in scenarios with limited clinical data, as well as to quan...
Authors: Kristina Bjegovic, Yong Chen, Gilberto Gonzalez, Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu
Affiliation: University of Maryland School of Medicine, University of California, Irvine, University of Oklahoma Health Sciences Center, University of Oklahoma Health Science Center
Abstract Preview: Purpose: Proton therapy is becoming an increasingly popular choice for cancer treatment due to its precision, reduced side effects, and effectiveness. While dosimetry is fundamental to the success of ...
Authors: Hyejoo Kang, Andrew Keeler, Mathias Lehmann, Jason Patrick Luce, Ha Nguyen, John C. Roeske
Affiliation: Varian Imaging Laboratory, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago
Abstract Preview: Purpose: Markerless tumor tracking (MTT) using dual-energy (DE) subtraction imaging is being considered as a non-invasive method to track tumors during lung cancer treatment. Prior to clinical impleme...
Authors: Brankica Andelic, Young-Bin Cho, Tara M. Gray, Bingqi Guo, Andrew Robert Hadfield, Hakan Nordstrom, Jacob Scott, John Suh, Nara Yoon
Affiliation: Adelphi University, Elekta, Cleveland Clinic
Abstract Preview: Purpose: To investigate the biological effect of Spatially Fractionated Radiation Therapy (SFRT) within Gamma-Knife (GK) using retrospective planning for brain metastases patients. This study presents...
Authors: Adebayo Abe, Samuel Olaolu Adeneye, Eben Aje, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Lilian Ekpo, Muhammad Habeebu, Adedayo O. Joseph, Charles S. Mayo, Noah Ndianaobong, Ikechi S Ozoemelam, Margaret Dideolu Taiwo, Godwin Uwagba
Affiliation: University of Michigan, University of Ibadan, University of Lagos, Missouri University of Science and Technology, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre, NSIA-LUTH Cancer Center
Abstract Preview: Purpose:
Head and neck cancers (HNC) present significant challenges in radiotherapy due to complex anatomy and the proximity to critical organs at risk (OARs). These challenges are compounded in na...
Authors: Alex Lindgren-Ruby, Jeffrey M. Moirano, Joseph Everett Wishart
Affiliation: University of Washington
Abstract Preview: Purpose:
To evaluate polynomial fitting of signal intensity for signal-to-noise ratio (SNR) estimation from weekly QC ACR MRI phantom images and compare against other SNR estimation methods as well...
Authors: Hengjie Liu, Dan Ruan, Ke Sheng, DI Xu
Affiliation: Physics and Biology in Medicine, University of California, Los Angeles, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose:
State-of-the-art deep learning-based deformable image registration often uses large, complex models directly adapted from computer vision tasks but achieves only comparable performance to ...
Authors: Austen N. Curcuru, Winter Green, Yao Hao, Jiayi Liu, Yuting Peng, Tiezhi Zhang, Xiandong Zhao
Affiliation: Washington University School of Medicine, Department of Radiation Oncology, WashU Medicine, Virginia Commonwealth University, Washington University School of Medicine, Washington University in St. Louis
Abstract Preview: Purpose: We proposed a treatment planning optimization method that utilizes customized spot map modification to achieve less dosimetry uncertainty, monitor unit ratio (MUR) and neutron dose in a spot ...
Authors: Kim Creach, Kim Howard, Julius G. Ojwang, Richard A. Shaw, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: To present a standardized MRI-CT hybrid workflow for High-Dose-Rate (HDR) Image-Guided Adaptive Brachytherapy (IGBT) in cervical cancer, aligned with AAPM TG-303, as a model to assist with im...
Authors: Eric C. Ford, Yulun He, Minsun Kim, Dustin Melancon, Juergen Meyer, Dong Joo Rhee, Yinghua Tao
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, MD Anderson Cancer Center, University of Washington
Abstract Preview: Purpose: To develop and evaluate an automated-planning technique capable of generating high-quality treatment plans for hippocampal-sparing-whole-brain radiation therapy.
Methods: An auto-planning ...
Authors: Hoyeon Lee
Affiliation: University of Hong Kong
Abstract Preview: Purpose: Deep-learning approaches are widely investigated for Cone-Beam CT (CBCT) scatter correction to improve the quality of the linear-accelerator mounted CBCT. This study aims to optimize the deep...
Authors: Nuraddeen Nasiru Garba, Kalpana M Kanal, Abdullahi Mohammed, Rabiu Nasiru, Muhammad SHAFIU Shehu, Daniel Vergara, Joseph Everett Wishart
Affiliation: AHMADU BELLO UNIVERSITY, ZARIA, University of Washington
Abstract Preview: Purpose: To establish local Diagnostic Reference Levels (DRLs) for head and neck computed tomography (CT) exams in Abuja, Nigeria, and to investigate the performance of brain metastasis (BM) and brain...
Authors: Kenny Guida, Daniel Johnson, Wesley Tucker
Affiliation: University of Kansas Medical Center, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Intensity modulated proton therapy (IMPT) has emerged as a standard of care for unilateral head and neck (HN) cancers due to superior OAR sparing. With the increase of proton centers national...