Authors: Ioannis Androulakis, Miranda E.M.C. Christianen, Jérémy Godart, Mischa Hoogeman, Inger-Karine K. Kolkman-Deurloo, Lorne Luthart, Remi A. Nout, Henrike Westerveld
Affiliation: Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam
Abstract Preview: Purpose:
Despite the advantages of transrectal ultrasound-based treatment planning for HDR prostate cancer brachytherapy which allows on-line treatment delivery in the intraoperative setting, it is...
Authors: Ioannis Androulakis, Jérémy Godart, Mischa Hoogeman, Inger-Karine K. Kolkman-Deurloo, Remi A. Nout, Robin Straathof, Henrike Westerveld, Myra van Laar
Affiliation: Department of BioMechanical Engineering, Delft University of Technology, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam
Abstract Preview: Purpose:
In brachytherapy for gynaecological cancers using intracavitary applicators, implant reconstruction is commonly performed using applicator libraries. These libraries contain applicator geo...
Authors: Harsh Arya, Yan Chang, Yujie Chi, Varghese Anto Chirayath, Joshua Rajan, Pan Zui
Affiliation: University of Texas at Arlington, Department of Physics, University of Texas at Arlington
Abstract Preview: Purpose: In targeted alpha therapy (TAT), absorbed dose rates can vary significantly spatially and temporally, impacting therapeutic efficacy as well as carcinogenic potential. This study reports the ...
Authors: Zhitao Dai
Affiliation: Chinese Academy of Medical Sciences Cancer Hospital Shenzhen Hospital
Abstract Preview: Purpose: To investigate the accuracy of 3D printed individualized vaginal template assisted pre-planning in the interstitial implantation of cervical cancer, to examine the advantages when compared wi...
Authors: Victor B. Kassey, Maciej M. Kmiec, Periannan Kuppusamy, Sergey V. Petryakov, Conner Ubert
Affiliation: Dartmouth College
Abstract Preview: Purpose: Tumor hypoxia—a state of reduced oxygen supply—is well known to affect treatment response, particularly in radiotherapy and chemotherapy. Oxygen-enhanced magnetic resonance imaging (OE-MRI) u...
Authors: Amy Tien Yee Chang, Chi Wai Cheung, Tin Lok Chiu, Chen-Yu Huang, Chi Wa Kong, Pei-Xiong Li, Pak Hang Nam, Bin Yang, Siu Ki Yu
Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital
Abstract Preview: Purpose: This study introduces BrachyPlanCheck, an independent Monte Carlo (MC)-based dose calculation tool for 192Ir brachytherapy retrospective study or algorithm commissioning.
Methods: BrachyPl...
Authors: Hamid Aghdam, DJ Chen, Heather Chen, Sharad Goyal, Yonas Solomon Mekuria, Martin Ojong-Ntui, Yuan James Rao
Affiliation: The George Washington University, The George Washington University Cancer Center
Abstract Preview: Purpose: Elekta Leipzig and Valencia Skin applicators are designed to treat skin lesions. The applicators limit the irradiation to the required treatment area using a densimet shielding. Valencia uses...
Authors: Ivan M. Buzurovic, Phillip M. Devlin, Evangelia Kaza, Michael John Lavelle
Affiliation: Department of Radiation Oncology, Dana-Farber/Brigham and Women’s Cancer Center, Harvard Medical School, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology
Abstract Preview: Purpose: Recent work in surface brachytherapy (SBT) has demonstrated the feasibility of using magnetic resonance (MR)-guidance in place of Computer Tomography (CT) in SBT planning. The purpose of this...
Authors: Brett Bocian, Patrick James Jensen, Luis Augusto Perles, Christopher J. Tien
Affiliation: Yale University School of Medicine, University of Miami, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center
Abstract Preview: Purpose: Guidelines for dose prescriptions in endometrial cancer are based upon depth from the cylinder, traditionally 5 mm or 0 mm (i.e., surface). There are no current single-channel vaginal cylinde...
Authors: Zachary R. Grelewicz, Kevin C. Jones, Yixiang Liao, Andrew Ogilvy, Julius V. Turian
Affiliation: Rush University Medical Center
Abstract Preview: Purpose: To demonstrate the accuracy and QA application of a time-resolved 3D gamma camera, we measured the path traversed by the Ir-192 High-Dose-Rate (HDR) brachytherapy source passing through a rin...
Authors: Hiroki Katayama, Hiroki Kawasaki, Motonori Kitaoka, Yosuke Takahashi, Takashi Tanii, Masato Tsuzuki
Affiliation: Kagawa University Hospital
Abstract Preview: Purpose:
Surface-guided radiotherapy (SGRT) with ExacTrac Dynamic (ETD) allows motion tracking and beam gating during treatment delivery. Accurate evaluation of beam-on and beam-off delays is essen...
Authors: Jingxi Weng, Jian Wu
Affiliation: University of Florida
Abstract Preview: Purpose: Modern brachytherapy treatment planning software includes pre-defined applicator models. However, previous studies have shown significant discrepancies between actual and model-based first dw...
Authors: Peter Balter, Thomas Alexander Cuthbert, Weiliang Du, Song Gao, Nicholas Zacharopoulos
Affiliation: Aktina Medical Corp, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: The purpose of this study is to evaluate the accuracy and reproducibility of a commercial product for verifying the size, location, and coincidence of physical isocenter (P_iso) and radiation...
Authors: Niels Bassler, Jonathan Bortfeldt, Carlos Granja, Guyue Hu, Margarita Kozak, Julie Lascaud, Kirsten Lauber, Grigory Liubchenko, Jasper Nijkamp, Cristina Oancea, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Brita Singers Sørensen, Matthias Würl
Affiliation: Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital, Advacam
Abstract Preview: Purpose: To apply in-vivo proton radiography (pRad) to aid image registration and treatment plan refinement for a novel precision image-guided small animal proton irradiation platform.
Methods:...
Authors: Davide Brivio, Erno Sajo, Ryan Williams, Piotr Zygmanski
Affiliation: University of Massachusetts Lowell, Brigham and Women's Hospital, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: To develop a non-invasive 3D in-vivo dosimetry tool exploring the relationship between positron annihilations and dose per voxel using Monte Carlo simulation. The Positron Guided Radiation Th...
Authors: Bryan Bednarz, John M. Floberg, Joseph B. Schulz, Jordan M. Slagowski
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Catheter placement for high-dose-rate brachytherapy (HDR BT) is clinician dependent and potentially suboptimal for delivering simultaneous integrated boosts to intraprostatic gross tumor volu...
Authors: Mojtaba Behzadipour, Suman Gautam, Tianjun Ma, Ikchit Singh Sangha, Bongyong Song, William Song, Kumari Sunidhi
Affiliation: UC San Diego, Virginia Commonwealth University
Abstract Preview: Purpose: This study aims to develop a knowledge-based voxel-wise dose prediction system using a convolutional neural network (CNN) for high-dose-rate (HDR) prostate brachytherapy and to evaluate its p...
Authors: Awens Alphonse, Nebi Demez, Brian P. Laffey, Shyam Pokharel, Suresh Rana, Nishan Shrestha
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: The Imaging Ring is a mobile digital X-ray system capable of producing 2D planar X-rays, fluoroscopy, and 3D Cone-Beam Computed Tomography (CBCT) images. This study aimed to evaluate the long...
Authors: Dirk A Bartkoski, Leonard Che Fru, Benjamin Abraham Insley, Michael Kleckner, Dongyeon Lee, Reza Reiazi, Mohammad Reza Salehpour, Aviad Schori, Ramesh C. Tailor
Affiliation: Empyrean Medical Systems, The University of Texas MD Anderson Cancer Center, Convergent-RnR, The University of Texas, MD Anderson, Houston TX
Abstract Preview: Purpose: A Geant4-based model was created for a G4BraggReflection process to simulate radiation transport within a novel radiotherapy system developed by Convergent Radiotherapy and Radiosurgery (CRnR...
Authors: Sam Beddar, Brett Bocian, David B. Flint, Benjamin Abraham Insley, Patrick James Jensen, Rachael M. Martin Paulpeter, Joshua S. Niedzielski, Luis Augusto Perles, Reza Reiazi, Gabriel O. Sawakuchi
Affiliation: University of Miami, MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Empyrean Medical Systems, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: The Harrison-Anderson-Mick (HAM) applicator is an Ir-192 High-Dose-Rate (HDR) intraoperative radiotherapy device. It features a silicone body with embedded catheters that guide the Ir-192 sou...
Authors: Jochen Cammin, Yushi Chang, Mariana Guerrero, Kai Jiang, Narottam Lamichhane, Elizabeth Nichols
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: Our institution handles a large GYN SYED patient load (5 HDR fractions over 3 days). In recent years, we faced many logistical challenges, such as broken/contaminated catheters, which disrupt...
Authors: Jonathan Dowell, Wei Luo, Shane McCarthy, Janelle A. Molloy, Markus Murphy
Affiliation: University of Kentucky, Department of Radiation Medicine, Iridesce Solutions, Inc.
Abstract Preview: Purpose: The novel machine quality assurance (QA) device nüFilm (Iridesce Solutions, Lexington KY) allows for an objective assessment of light and radiation fields independent of setup. Herein, the ab...
Authors: B. Gino Fallone, Gawon Han, Keith D. Wachowicz, Mark G. Wright, Eugene Yip, Jihyun Yun
Affiliation: Medical Physics Division, Department of Oncology, University of Alberta, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta, Medical Physics Division, Department of Oncology, University of Alberta and Department of Medical Physics, Cross Cancer Institute, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta; MagnetTx Oncology Solutions, www.magnetTX.com
Abstract Preview: Purpose: MRI-radiotherapy hybrid systems can guide the therapeutic beam, dynamically adjusting to a moving tumor in real-time. However, there is a time delay from imaging and beam control, requiring p...
Authors: Timothy J Allen, Clara Ferreira
Affiliation: University of Minnesota, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: Presurgical treatment planning for GammaTile cranial implants is limited to estimates of required tiles and provides no positioning information. Existing tools are intended for tile estimatio...
Authors: James L. Giltz, Michael J. Merrick
Affiliation: Alyzen Medical Physics, University of Kentucky
Abstract Preview: Purpose: To evaluate the capability of MyQA SRS in performing high-resolution machine QA to verify multileaf collimator (MLC) behavior and integrity for adaptive radiotherapy (ART). This study demonst...
Authors: Salim Balik, Eric Chang, Kristine Garcia, Andrew Islas, Lijun Ma, Zhilei Liu Shen, Elizabeth Zhang-Velten
Affiliation: Radiation Oncology, Keck School of Medicine of USC
Abstract Preview: Purpose: NRG protocols recommend simulating and treating head and neck (HN) cancer patients in a supine position for optimal setup reproducibility. However, certain patients cannot tolerate the supine...
Authors: Leon Dunn
Affiliation: IsoAnalytics Pty. Ltd.
Abstract Preview: Purpose: The purpose of this work is to present the development and results of an automated Varian Trajectory Log file processing software platform called Sentinel (IsoAnalytics Pty. Ltd.).
Methods...
Authors: Kim Creach, Kim Howard, Julius G. Ojwang, Richard A. Shaw, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: To present a standardized MRI-CT hybrid workflow for High-Dose-Rate (HDR) Image-Guided Adaptive Brachytherapy (IGBT) in cervical cancer, aligned with AAPM TG-303, as a model to assist with im...
Authors: Baozhu Lu, Hongjing Sun, Timothy C. Zhu, Yifeng Zhu
Affiliation: University of Pennsylvania
Abstract Preview: Purpose: This study aims to validate the feasibility of using Cherenkov imaging for surface dose distribution measurement during Total Skin Electron Therapy (TSET) by developing a perspective-correcte...
Authors: Xiu tong Lin
Affiliation: Department of Radiation physics and technology, Shandong Second Provincial General Hospital
Abstract Preview: Purpose: To compare the dosimetric differences between the photon and proton plans and between the different target according to the placement of the implants for patients undergoing radiotherapy afte...
Authors: Owen Thomas Dillon, Andrew Kanawati, Tess Reynolds
Affiliation: Westmead Hospital, Image X Institute, Faculty of Medicine and Health, The University of Sydney
Abstract Preview: Purpose: Metal artefacts from implanted hardware and surgical tools remain a limitation for widespread adoption of intraoperative CBCT imaging. Gantry-based non-circular imaging trajectories have emer...
Authors: Stephen R. Bowen, Shijun Chen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Qianqian Tong, Jiajie Wang, Shouyi Wang, Faisal Yaseen
Affiliation: The University of Texas at Austin, Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Fred Hutchinson Cancer Center, University of Texas at Arlington
Abstract Preview: Purpose: Tumor subregion clustering and prediction of region-specific response can augment assessments and adaptive treatment decisions. A modeling framework was constructed to predict chemoradiation ...
Authors: Michael B. Altman, Sharbacha Edward, Jose L. Garcia Ramirez, Anamaria Guta, Elizabeth Gaines Jeong, Justin K. Mikell, Phillip D. H. Wall, Jacqueline Esthappan Zoberi
Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, WashU Medicine
Abstract Preview: Purpose: Modern HDR remote afterloaders (RAL) are equipped with enhanced safety features for accurate source positioning. However, little guidance is provided on the use of these features. We have cli...