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Results for "dynamic contrast": 19 found

3D Topological Features for Outcome Assessment of Therapeutic Responses to Neoadjuvant Chemoradiotherapy (NCRT) with and without Anti-CD40 Immunotherapy in Local Advanced Rectal Cancer (LARC)

Authors: Todd A Aguilera, Gaurav Khatri, Jiaqi Liu, Hao Peng, Nina N. Sanford, Robert Timmerman, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT southwestern medical center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
This study first integrates 3D topological data analysis with radiomics from local advanced rectal cancer T2-weighted MRI to evaluate therapeutic responses and quantify treatment-induced c...

A Novel Method for Virtual Extension of Image-Derived Vasculature Segmentations

Authors: Raneem Atta, Alejandro Bertolet, Mislav Bobić, Wesley E. Bolch, Robert Joseph Dawson, Carlos Huesa-Berral, Harald Paganetti, Eric Wehrenberg-Klee

Affiliation: Massachusetts General Hospital, University of Florida, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Massachusetts General Hospital and Harvard Medical School, Department of Radiology, Massachusetts General Hospital and Harvard Medical School

Abstract Preview: Purpose: Representations of intra-organ vasculature have a variety of uses in the field of computational dosimetry but generally rely on models derived from population-averaged reference individuals. ...

An Optimal-Mass-Transport-Based Mathematical Model Applied to Brain DCE-MRI to Differentiate Brain Metastases Recurrence from Radiation Necrosis

Authors: Aditya P. Apte, Xinan Chen, Joseph O. Deasy, Ramesh Paudyal, Kyung Peck, Amita Shukla-Dave, Nathaniel Swinburne, Robert J. Young

Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: We apply our novel formulation of unbalanced-regularized-optimal-mass-transport (urOMT) theory to brain DCE-MRI data to quantify and visualize the behaviors of fluid flows in post-treatment f...

Dynamic Angular Couch Kinematics in Radiotherapy

Authors: Eva Lee, R. Lee MacDonald, Alasdair Syme, Christopher G. Thomas

Affiliation: Department of Radiation Oncology, QE2 Cancer Centre, Nova Scotia Health, Dalhousie University, Nova Scotia Health

Abstract Preview: Purpose:
Dynamic couch rotation in radiotherapy offers dosimetric benefits, however patient comfort remains a concern. This study investigates couch kinematics in trajectory-based radiotherapy plan...

Dynamic X-Ray Acoustic Computed Tomography (XACT)

Authors: Leshan Sun, Liangzhong Xiang, Yifei Xu, Yuchen Yan

Affiliation: University of California, Irvine

Abstract Preview: Purpose: X-ray Acoustic Computed Tomography (XACT) is a transformative innovation in medical imaging, overcoming the limitations of conventional X-ray techniques. It introduces new possibilities in cl...

Evaluating Phantom Usability for Thermal Imaging Localization in Radiation Therapy

Authors: Nema Bassiri, Kristen A. Duke, Neil A. Kirby, Thomas Wilson Klender, Christien Kluwe, Niko Papanikolaou, Holly Paschal, Karl H. Rasmussen, Daniel L. Saenz, Michelle de Oliveira

Affiliation: Miami Cancer Institute, University of Texas HSC San Antonio, UT Health San Antonio

Abstract Preview: Purpose: Determine the practical usability for three phantoms to be used with the ExacTrac Dynamic thermal imaging system. Thermal-guided imaging can be used for inter and intra motion management, pat...

Evaluation of the Improvements of a New Leaf Model (Enhanced Leaf Model) for the Halcyon

Authors: Evan Barber, Gloria P. Beyer, Callum Hartley, Jordi Saez, Philip Wheeler

Affiliation: Department of Radiation Oncology, Hospital Clinic de Barcelona, Department of Radiotherapy Physics, Velindre University NHS Trust, Medical Physics Services, LLC

Abstract Preview: Purpose: To evaluate the Enhanced Leaf Model (ELM) in Eclipse v18 to the standard leaf model for the Halcyon multileaf collimator (MLC) using a measurement-based method.
Methods: The Halcyon’s doub...

Feasibility Study on Creating a Digital Twin of Digital Subtraction Angiography Data Utilizing Monte Carlo and Computational Fluid Dynamic Simulations

Authors: Ciprian N. Ionita, Parisa Naghdi, Ahmad Rahmatpour

Affiliation: University at Buffalo, SUNY: University at Buffalo

Abstract Preview: Purpose: Quantitative angiography (QA) evaluates neurovascular hemodynamics, but is affected by X-ray parameters, vessel foreshortening, and imaging chain factors like detector efficiency, pixel size,...

From Noisy Signals to Accurate Maps: Transforming Look-Locker MRI with an Intelligent T₁ Estimation

Authors: Prabhu C. Acharya, Hassan Bagher-Ebadian, Stephen L. Brown, James R. Ewing, Mohammad M. Ghassemi, Benjamin Movsas, Farzan Siddiqui, Kundan S Thind

Affiliation: Michigan State University, Oakland University, Henry Ford Health

Abstract Preview: Purpose: Accurate T1 quantification using T One by Multiple Read Out Pulse (TOMROP) sequences is essential for physiological assessments in dynamic-contrast-enhanced (DCE) MRI and T1 mapping studies. ...

Functional MRI Guided Partial Tumor Irradiation to Improve Tumor Control and Spare Tumor Microenvironment

Authors: Bingqi Guo, Ping Xia

Affiliation: Cleveland Clinic

Abstract Preview: Purpose:
Spatially fractionated radiation therapy (SFRT) delivers a “GRID” or “lattice” of high and low doses to tumors to increase tumor control, minimize normal tissue damage, and preserve the im...

Image Quality Improvement Using a Patient-Specific Post-Trigger Delay Protocol for Coronary CT Angiography

Authors: Cecelia Brewington, Connor Edwards Miles All Leska-Kent, Kyrillos Grace, Katherine Hyde, Sabee Molloi, Shiva Mostafavi, Liqiang Ren, Alireza Shojazadeh, Justin Truong

Affiliation: Department of Radiology, UT Southwestern Medical Center, University of California, Irvine, University of Texas Southwestern

Abstract Preview: Purpose: To retrospectively assess image quality in coronary CT angiography (CCTA) using a patient-specific post-trigger delay (PTD) protocol, developed using half of the injection time plus a dispers...

Intraoperative Dynamic Contrast-Enhanced Fluorescence Imaging in Quantifying Tissue Perfusion of Amputation Patients

Authors: Logan M. Bateman, Xu Cao, Jonathan T. Elliott, Lillian A. Fisher, Ida Leah Gitajn, Xinyue Han, Eric R. Henderson, Shudong Jiang, Jessica M. Sin, Yue Tang

Affiliation: Dartmouth College, Dartmouth-Hitchcock Medical Center

Abstract Preview: Purpose: Adequate tissue perfusion is essential for fracture healing and infection prevention, as it supplies oxygen, nutrients and antibiotics to the injury area. However, current methods of assessin...

Investigating Interstitial Fluid Pressure and Hydraulic Conductivity By Examining the Biophysical Properties of Drug Transport Using Cross Voxel Exchange Model and Dynamic Contrast Enhanced MRI

Authors: Catherine Coolens, Janny Yeyoung Kim, Michael Milosevic, Noha Sinno

Affiliation: Princess Margaret Hospital, University of Toronto

Abstract Preview: Purpose: In solid tumors, Interstitial fluid pressure (IFP) acts as a barrier to molecular transport to the tumor center and serves as a predictor of cancer patients’ treatment responsiveness. The nov...

Non-Planar Narrow-Beam CT: Near Scatter-Free, High-Resolution Breast Imaging at Screening Mammography Doses.

Authors: Peymon Ghazi

Affiliation: MALCOVA Inc.

Abstract Preview: Purpose: To develop a near scatter‐free breast CT imaging system that expands coverage of the posterior breast anatomy and enhances contrast resolution for solid masses and microcalcifications, while ...

Patient-Specific Ultra-Sparse k-Space Reconstruction Using Motion Decomposition and Sinusoidal Representation Networks for Dynamic Volumetric MRI in Radiotherapy

Authors: Karyn A Goodman, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Qian Wang, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Beth Israel Deaconess Medical Center

Abstract Preview: Purpose: Accurate motion management in MRI-guided radiotherapy (MRIgRT) relies on real-time volumetric MRI to track intra-fractional anatomical changes. Dense k-space sampling, while capable of produc...

Predicting Pathological Complete Response to Neoadjuvant Chemotherapy for Breast Cancer at Early Time Points Using a Two-Stage Dual-Task Deep Learning Strategy

Authors: Bowen Jing, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Medical images acquired at multiple time points during neoadjuvant chemotherapy allow physicians to assess patients’ responses and personalize treatment plans accordingly. Studies from the I-...

Robustness Evaluation of Dynamic Arc Proton Therapy: A Comparative Analysis of Small and Large Spot Sizes in Lung and Prostate Cancer Planning

Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Hina Saeed, Gagandeep Saini, Nishan Shrestha, Somol Sunny

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: This study evaluates the robustness of DynamicARC proton therapy plans for lung and prostate cancer, comparing small spot size (SS) and large spot size (LS) plans under nominal and worst-case...

Synthetic Spheres: Ultrasound Image Quality Assessment with a Uniform Phantom

Authors: Ted Lynch

Affiliation: Sun Nuclear, a Mirion Medical Company

Abstract Preview: Purpose: A novel ultrasound quality assurance method is presented that constructs “synthetic spheres” at arbitrary locations within the image frame by combining correlation length measurements from a ...

Use of Edge-Driven Modified Fuzzy C-Means Algorithm in DCE-MRI Image Sequences for Prostate Cancer Lesion Segmentation

Authors: Ilias Gatos, Stavros Grigoriadis, George C. Kagadis, Maria Karamesini, Paraskevi Katsakiori, Dimitris N. Mihailidis, Stavros Spiliopoulos, Efstratios Syrmas, Ioannis Theotokas, Stavros Tsantis, Pavlos Zoumpoulis

Affiliation: Diagnostic Echotomography, University of Pennsylvania, University of Athens, University of Patras

Abstract Preview: Purpose: To detect prostate lesions on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) images which is a particularly difficult task due to the heterogeneous and inconsistent representa...