Authors: Dale W. Litzenberg, Ikechi S Ozoemelam, Rowan Paplanus, Michael Pillainayagam, Donald A. Roberts
Affiliation: University of Michigan, Oregon Health & Science University
Abstract Preview: Purpose: Clinical linear accelerators use dual foil scattering systems designed to achieve large uniform fields (up to 25×25cm²), which can reduce beam fluence by up to 93% compared to the unmodified ...
Authors: Gulakhshan M Hamad, Sina Mossahebi, Yannick P. Poirier, Amit Sawant
Affiliation: University of Maryland School of Medicine, Maryland University Baltimore
Abstract Preview: Purpose:
The combination of ultra-high dose rate (UHDR) proton therapy, known for normal tissue sparing, with spatially-fractionated radiotherapy (SFRT), promising enhanced tumor control and tissue...
Authors: Min Cheol Han, Chae-Seon Hong, Changhwan Kim, Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, HO Lee, Kwangwoo Park, Ye-In Park, Junyoung Son
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Yongin Severance Hospital, Yonsei University College of Medicine
Abstract Preview: Purpose: Overresponse in surface in-vivo dosimetry using optically stimulated luminescence dosimeter (OSLD) depends on the beam incidence angle. This study aimed to investigate correction factors to d...
Authors: Edward A. Opalko, Matthew B. Podgorsak, Dheerendra Prasad
Affiliation: Roswell Park Comprehensive Cancer Center
Abstract Preview: Purpose: To design a 3D printed insert for Varian’s SRS Head Phantom that allows for multi-planar film dosimetry and to evaluate its ability in end-to-end testing for Gamma Knife treatments.
Method...
Authors: Dr. Sheaka Alobaidli, Anju K V, Dr. Chiranjib Konar, Sreejesh MS, Dr. Vijayaprabhu N, Dr. Deepti Sharma, Dr. Hanuman Prasad Yadav
Affiliation: Amity Institute of Applied Sciences, Kuwait Cancer Control Center, Institute of Liver and Biliary Sciences, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Amity institute of Applied Sciences, Amity University, Institute of Liver and Biliary Sciences(ILBS)
Abstract Preview: Purpose:
The accuracy of dose delivery in stereotactic body radiotherapy (SBRT) is critical for effectively treating hepatocellular carcinoma (HCC). This study aims to develop patient-specific 3D-p...
Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Arnab Chakravarti, Nilendu Gupta, Sagarika Jain, Maximilian Stephen Meineke, Allison N. Palmiero, Runhe Tan
Affiliation: The Ohio State University - James Cancer Hospital, Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center, The Ohio State University, The James Cancer Center
Abstract Preview: Purpose: Ultra-High Dose Rate Radiation Therapy (UHDR-RT) induces normal tissue sparing while maintaining iso-effective tumor control compared to conventional methods, known as the “FLASH effect”. How...
Authors: Christoph Bert, Leon Brückner, Luitpold Distel, Julian Freier, Peter Hommelhoff, Bastian Löhrl
Affiliation: Department of Radiation Oncology, Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Department Physik, Friedrich-Alexander Universität Erlangen-Nürnberg
Abstract Preview: Purpose: Low energy electron (LEE) bunches in the kilo electronvolt (keV) range are thought to have a high relative biological effectiveness (RBE). To investigate this, it is necessary to establish re...
Authors: Yijian Cao, Jenghwa Chang, Nicholas Coupey, Lyu Huang, Jessica Jung
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose:
The Synergy bioabsorbable polymer (BP) stent, made of Platinum Chromium Alloy, is widely utilized in treating coronary artery disease. This study investigates dose perturbations caused by ...
Authors: Darwin Abraham Garcia, Michael P. Grams, Scott C Lester, Maryam Mashayekhi, Douglas John Moseley, Robert W Mutter, Sean S Park, Chrystian Quintero Mateus
Affiliation: Mayo Clinic - Rochester, Mayo Clinic
Abstract Preview: Purpose: MBRT delivers sub-millimeter wide regions of high “peak” (~10s Gy) and low “valley” (~1 Gy) doses to treat cancer. MBRT commissioning is performed in flat, uniform plastic water. Thus, differ...
Authors: Milad BaradaranGhahfarokhi, Ashley Elizabeth Bonner, James R. Burns, Annie Cooney, George X. Ding, Kenneth L. Homann, Guozhen Luo
Affiliation: Corewell Health William Beaumont University Hospital, Vanderbilt University Medical Center
Abstract Preview: Purpose: The goal of this study was to evaluate the performance of a new plastic scintillating detector (PSD) system with 0.5×0.5 mm2 and 1.0×1.0 mm2 probes (referred to as Medscint0.5 and Medscint1.0...
Authors: Robert Berry, John Buatti, Nathan Burger, Ryan T. Flynn, Greg Johns, Maksim Kravchenko, Sergey Kutsaev, Yen-Po Lee, Marcos Ruelas, Joel J. St-Aubin, Timothy J. Waldron
Affiliation: RadiaBeam Technologies, University of Iowa
Abstract Preview: Purpose: To report the factory acceptance tests of a preclinical linear accelerator, the FLEX-9 electron FLASH linac from RadiaBeam Technologies.
Methods: The FLEX-9 FLASH electron linac is designe...
Authors: Rohith Kaiyum, Ozzy Mermut, Alexandra Rink
Affiliation: Department of Medical Biophysics, University of Toronto, Department of Physics and Astronomy, York University
Abstract Preview: Purpose: To investigate the relationship between chemical features and real-time response to ionizing radiation dose of radiochromic diacetylene crystals.
Methods: A number of radiochromic diacetyl...
Authors: Denise Dunn, Scott R. Floyd, Tyler V. Kay, Anna Lynnette-Price, Eric L. Martin, Stepan Mikhailov, Taylor Nguyen, Mark Oldham, Victoria J. P. Radosova, Zachary J. Reitman, Ramona Rodriguiz, Andrew Thompson, William Wetsel, Seth Wilcox, Ying Wu
Affiliation: Duke University Mouse Behavior Core, Department of Physics, Duke University, Medical Physics Graduate Program, Duke University, Duke University Medical Physics Program, Duke University, Duke University Mouse Behavioral and Neuroendocrine Analysis Core Facility, Department of Radiation Oncology, Duke University Medical Center
Abstract Preview: Purpose: FLASH radiation therapy (RT) shows promise for reducing normal tissue damage, though its mechanisms remain unclear. Using an in-vivo model with the High Intensity Gamma-ray Source (HIGS) lina...
Authors: Slade J. Klawikowski, Natalya V. Morrow, Haidy G. Nasief, Eric S. Paulson, An Tai, Hualiang Zhong
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Gafchromic film is commonly used for quality assurance in SRS/SBRT. However, its application in low-dose measurements, such as monitoring doses on cardiac implantable electronic devices—where...
Authors: Wesley S. Culberson, Aleksandra Ilina, Brian W Pogue, Matthew Reed, Connor Strainis, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel
Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin–Madison, University of Wisconsin-Madison, University of Wisconsin - Madison
Abstract Preview: Purpose: FLASH radiotherapy reduces skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR), while preserving damage to tumor tissue. The FLASH effec...
Authors: Mohammad Nazmul Alim, Regina DeWitt
Affiliation: Department of Physics, East Carolina University,, Department of Physics, East Carolina University
Abstract Preview: Purpose: This study quantifies the ability of Luxel (Al₂O₃:C) to measure radiation dose from a Moxtek X-ray source. Key aspects of OSL dosimetry, including OSL curves, dose response, depth dose, and b...
Authors: Omer Abdulaziz Ali, Robin Hill, Nathan Huntelerslag
Affiliation: Waikato Hospital, Hamilton, New Zealand, Central Coast Cancer Centre, Gosford, Australia
Abstract Preview: Purpose: Characterizing transmission through eye shields is essential to understanding dose distribution in underlying tissues. This study aims to utilize Monte Carlo (MC) simulations to model and cha...