Authors: Mitya M. Barreto, Nichole A. Harris
Affiliation: Department of Radiology, University Hospitals Cleveland Medical Center
Abstract Preview: Purpose: To evaluate dosimeter dependence of measured AGD, and to develop a dosimeter independent method for evaluating the AGD, for CEDM exposures.
Methods: Three solid-state dosimeters (Raysafe-X...
Authors: Dale Black, David Clymer, Huanjun Ding, Hamidreza Khodajou Chokami, Sabee Molloi, Christine Vy Nguyen, Tim Sananikone, Alireza Shojazadeh, Randy Wang
Affiliation: Department of Radiological Sciences, University of California, University of California, Department of Radiological Sciences, University of California, Irvine, Department of Radiological Sciences, University of California, Irvine
Abstract Preview: Purpose: We present a novel multi-material decomposition (MMD) algorithm for accurate quantification of material concentration in reconstructed dual-energy CT images. This method addresses limitations...
Authors: Maria F. Chan, Seng Boh Gary Lim, Shih-Chi Lin, Dustin W. Lynch, Usman Mahmood, Jeonghoon Park
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To explore the feasibility of using GafChromic LD-V1 film for annual imaging dose assessment across kV radiography, fluoroscopy, and cone beam computed tomography (CBCT) imaging protocols, as...
Authors: Steven Brown, Mike Hopkins, Jerimy C. Polf, Scott Sawyer, Benjamin L. Viglianti
Affiliation: H3D, inc, University of Michigan, M3D, Inc, M3D Imaging
Abstract Preview: Purpose: We characterized the sensitivity, energy dependence, and calibrated dose rate for a radiation imaging survey meter (RAVIN Cam; M3d inc., Ann Arbor MI) based on cadmium zinc telluride (CZT) cr...
Authors: Dominique Guillet, Arthur Lalonde, Bryan R. Muir, James Renaud, Karim Zerouali
Affiliation: Universite de Montreal, Centre Hospitalier de l'Universite de Montreal, National Research Council
Abstract Preview: Purpose:
To evaluate the dose rate dependence, beam quality dependence, and short-term stability of a novel flashDiamond (fD) prototype detector for conventional and ultra-high dose rate (UHDR) bea...
Authors: Amar K. Basavatia, Lee C. Goddard, Rachel Grimm, Wolfgang A. Tomé
Affiliation: Montefiore Medical Center
Abstract Preview: Purpose: To characterize the “MyOSL Chip” OSLD system for clinical use and compare the response of multiple readers to allow for utilization in a multi-clinic environment.
Methods: Dose calibration...
Authors: Maria F. Chan, Indra J. Das, Xiuxiu He, Seng Boh Gary Lim, Jeonghoon Park, Yunjie Yang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: There is a need for accurate and flexible in-vivo dosimetry systems, particularly for special procedures. Effective dosimetry is crucial for dose verification and maintaining records. A new r...
Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: The dependence of CT number on position in the field-of-view (FOV) imposes challenges in radiotherapy treatment planning. This study aims to decrease this dependence using photon counting det...
Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: To assess the dependency of CT numbers on position in the field-of-view (FOV) using single-energy (SE) and dual-energy (DE) images and energy-integrating detector (EID) and photon-counting de...
Authors: Wesley S. Culberson, Ryan Gardner, Patrick M Hill, Mark Pankuch, Karsten K. Wake
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Wisconsin, Northwestern Medicine Proton Center
Abstract Preview: Purpose: To assess the dosimetric capabilities of Sun Nuclear (Melbourne, FL) EDGE Diode Detectors™ for measurements in the plateau region of pencil beam scanning (PBS) fields. Many clinical dosimeter...
Authors: John Ford, Yu Fujiwara, Isao Murata, Zavier Ndum Ndum
Affiliation: Osaka University, Texas A&M University
Abstract Preview: Purpose: This study investigates how particle energy affects radiation quality and biological effectiveness with the inclusion of medical implants. Our research group used microdosimetric analysis to ...
Authors: Yoshihiko Hoshino, Kenji Hotta, Taeko Matsuura, Ai Nakaoka, Hidenobu Tachibana
Affiliation: Hokkaido University, Department of Radiology, Gunma University Hospital, Radiation Safety and Quality Assurance Division, National Cancer Center Hospital East
Abstract Preview: Purpose: Gel dosimeters enable three-dimensional dose measurements, but no reports have evaluated the fundamental performance of VIPER-type gel dosimeters in proton beam measurements. Therefore, we ev...
Authors: Wesley S. Culberson, Larry A. DeWerd, Ahtesham Ullah Khan, Zachary James Welchel
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: Flattening filter free (FFF) linac beams exhibit a centrally peaked beam profile due to the forward-directed bremsstrahlung production from MeV electrons, leading to volume averaging effects ...
Authors: Caroline Esposito, Keith T Griffin, Jae Won Jung, Choonik Lee, Choonsik Lee, Matthew Mille, Harald Paganetti, Sergio Morato Rafet, Jan PO Schuemann, Jungwook Shin, Torunn I Yock
Affiliation: East Carolina University, University of Michigan, Massachusetts General Hospital, National Cancer Institute, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: The National Cancer Institute’s Pediatric Proton and Photon Therapy Comparison Cohort aims to collect and analyze data from cancer centers across the United States and Canada to quantify diff...
Authors: Lili Chen, Dusica Cvetkovic, Chang Ming Charlie Ma, Dae-Myoung Yang
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: 5-aminolevulinic acid (5-ALA)-mediated radiodynamic therapy (RDT) has been shown to be an effective treatment option using high-energy photon beams. RDT utilizes tumoricidal capabilities caus...
Authors: Konstantinos Chatzipapas, George C. Kagadis, Panagiotis Konstas, Dimitris N. Mihailidis, Dimitris Visvikis
Affiliation: LaTIM, INSERM UMR1101, University of Pennsylvania, LaTIM, INSERM, University of Brest, University of Patras
Abstract Preview: Purpose: This study investigates the temporal evolution of radiolytic species (H3O+, OH•, OH-) in water under electron and proton irradiation using the mesoscopic chemistry model that allows longer te...
Authors: Ruiming Chen Edmondson, Darwin Abraham Garcia, James A. Kavanaugh, Joseph John Lucido
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Characterize the dose response and reproducibility of a low-dose film for 6 MV photon beam and assess the film’s energy dependence between kV and MV energies.
Methods: A single 8’x10’ LD-V...
Authors: Larry A. DeWerd, Ahtesham Ullah Khan
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison
Abstract Preview: Purpose: Total body irradiation (TBI) technique uses high energy photon beams with extended source-to-surface distances (SSDs) to irradiate the entire patient to prepare them for bone marrow or stem c...
Authors: Frank F. Dong, Megan C. Jacobsen, Ke Li, Xinming Liu, John Rong
Affiliation: UT MD Anderson Cancer Center
Abstract Preview: Purpose: We aimed to understand the physical performance of a CdTe PCD-based detector system within a whole-body PCD-CT scanner, with the goal of optimizing its clinical application. Instead of relyin...
Authors: Jeffrey S. Nelson, Raj Kumar Panta, Megan K. Russ, Ehsan Samei
Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: Contrast-enhanced mammography (CEM) enhances tumor detection by utilizing energy-dependent information from iodinated contrast agents. However, there is a lack of quantitative techniques to a...
Authors: Kuan Ling Chen, Jiajin Fan, Rao Khan, Robabeh Rahimi
Affiliation: University of Maryland, Inova Schar Cancer Institute, Howard University
Abstract Preview: Purpose: This study evaluates the dose response, energy dependency, sensitivity, reproducibility, temporal response, and LET dependency along and in the plane perpendicular to a clinical proton beam f...
Authors: Guang-Pei Chen, Renae Conlin, Juan A. Garcia-Alvarez, Kirk Morris, Haidy G. Nasief, Eenas A. Omari, Eric S. Paulson
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Cumulative dose limits make replacing and calibrating Metal Oxide Semiconductor Field Effect dosimeters (MOSFET-d) used for in-vivo dosimetry a common clinical task. Calibration protocols for...
Authors: Frank F. Dong, Megan C. Jacobsen, Ke Li, Xinming Liu, Humberto Monsivais, John Rong
Affiliation: Purdue University, UT MD Anderson Cancer Center
Abstract Preview: Purpose: To investigate the noise characteristics of a clinical photon counting detector CT (PCD-CT) system along axial and through-plane (Z) dimensions using 3D NPS measurements.
Methods: This stu...
Authors: Chingyun Cheng, Ben Durkee, Carri K. Glide-Hurst, Minglei Kang, Haibo Lin, Bhudatt R. Paliwal, Charles B. Simone, Zhizhen Wei, Tengda Zhang, Xingyi Zhao
Affiliation: University of Wisconsin, Department of Mechanical Engineering, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Transmission Beam (TB), Single-Energy Bragg Peak (SEBP), and Single-Energy Spread-Out Bragg Peak (SESOBP) are primary proton conformal FLASH techniques. However, each comes with significant l...
Authors: Dong Wook Kim, Jin Sung Kim, Dongho Lee, Sangmin Lee
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Seoul, Korea, Republic of (South)
Abstract Preview: Purpose:
This study aims to analyze the characteristics of a novel detector based on a dielectric layer (Vieworks Co., Korea), which demonstrates high tolerance to high radiation doses and light tr...
Authors: Jae Won Jung, Choonsik Lee, Jason C. Mace, Sergio Morato Rafet
Affiliation: East Carolina University, Carilion Clinic, National Cancer Institute
Abstract Preview: Purpose: Dosimetry for radionuclides used in nuclear medicine can be accurately calculated if sufficient data is available. However, in most cases crucial information cannot or will not be known a pri...