Search Submissions 🔎

Results for "enhanced power": 65 found

3D Topological Features for Outcome Assessment of Therapeutic Responses to Neoadjuvant Chemoradiotherapy (NCRT) with and without Anti-CD40 Immunotherapy in Local Advanced Rectal Cancer (LARC)

Authors: Todd A Aguilera, Gaurav Khatri, Jiaqi Liu, Hao Peng, Nina N. Sanford, Robert Timmerman, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT southwestern medical center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
This study first integrates 3D topological data analysis with radiomics from local advanced rectal cancer T2-weighted MRI to evaluate therapeutic responses and quantify treatment-induced c...

A Modular Approach to Reversible and Stackable Medical Imaging Translation Models: CBCT-Based Synthetic MRI with Multiple U-Nets in Series (MUNETs)

Authors: Eric Chang, Nguyen Phuong Dang, Andrew Lim, Lauren Lukas, Lijun Ma, Yutaka Natsuaki, Zhengzheng Xu, Hualin Zhang

Affiliation: Radiation Oncology, Keck School of Medicine of USC

Abstract Preview: Purpose: Harnessed the power of AI and Deep Learning (DL), Generalized Neural Network models for medical image transformation are trained to predict target images from reference images, often requirin...

A Novel Feature Selection Method for Survival Prediction of Head-and-Neck Following Radiation Therapy

Authors: Xiaoying Pan, X. Sharon Qi

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, School of Computer Science and technology,Xi'an University of Posts and Telecommunications

Abstract Preview: Purpose:
Survival prediction for cancer presents a substantial hurdle in personalized oncology, due to intricate, high-dimensional medical data. Our study introduces an innovative feature selection...

An Automated Solution to Staged Treatments for Arteriovenous Malformations in Gammaknife

Authors: Strahinja Stojadinovic, Robert Timmerman, Yulong Yan

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas Southwestern Medical Center, University of Texas Southwestern Medical Center

Abstract Preview: Purpose: Radiosurgery for large (>10cc) arteriovenous malformations (AVMs) poses significant challenges due to increased risks of complications and lower obliteration rates. To mitigate toxicity, larg...

Analysis of Noise Power Spectra in MR Parallel Imaging

Authors: Sulaiman D. Aldoohan, Gerardo Garcia

Affiliation: University of Toledo Medical Center

Abstract Preview: Purpose: To evaluate the noise power spectra (NPS) of images acquired using parallel imaging with varying acceleration factors in 1-D and 3-D spaces and to compare the level of the power of the noise ...

Assessing Mlc Errors and Their Dosimetric Impact Delivered on Elekta Linear Accelerator from Two TPS Systems

Authors: Richard Lesieur, Olivia Magneson, David E. Solis, Sotirios Stathakis

Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center

Abstract Preview: Purpose: This study evaluates the deliverability and precision of multileaf collimator (MLC) positioning in treatment plans generated by two different Treatment Planning Systems (TPS), Monaco and Pinn...

Assessing Skin Microcirculation in Breast Cancer Radiotherapy: Effectiveness of a Specialized Bra Compared in Two Hypofractionated Protocols.

Authors: Rosa Maria Cibrián Ortiz de Anda, Altea C Esteve, Carlos M Galindo-González, Carmen C García, Amparo Gonzalez-Sanchis, Jose C Gordo-Partearroyo, Emilio Soria-Olivas, Javier Vijande

Affiliation: IFIC-UV, Valencia University, Hospital General Universitario

Abstract Preview: Purpose: To determine how skin microcirculation is affected by the two hypo-fractionated radiotherapy protocols in breast cancer patients using Laser Doppler Imaging, a non-invasive method for assessi...

Assessment of Radiation Protection Knowledge Among Operation Professional Nurses

Authors: Yu-Ying Lin

Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou

Abstract Preview: Purpose: This study aimed to evaluate the level of radiation protection knowledge among operating room professional nurses.

Methods: A questionnaire was distributed to operating room profession...

Centralizing Resources with a Microsoft-Based Wiki Platform: Enhancing Collaboration and Efficiency in Radiation Oncology

Authors: Simon Brundage, Jiajin Fan, Ulrich Langner, Qiongge Li, Jian Liu, Wei Nie, Edwin Quashie, Xiaofeng Zhu

Affiliation: Brown University Health, Hofstra University Medical Physics Program, Inova Hospital, Inova Schar Cancer Institute, Indiana University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose:
Managing departmental policies, clinical protocols, QA procedures, workflows, and troubleshooting documentation is critical in radiation oncology. A Microsoft-based wiki platform was devel...

Deep-Dive Comparative Assessment between Digitally Reconstructed Radiographs and X-Ray Digital Radiographs from Lung CT Scans

Authors: Xinyi Fu, Dan Ruan, Ke Sheng

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose:
Digitally reconstructed radiographs (DRRs) are easy to generate and widely used to establish research protocols in pulmonary diagnosis and image-guided radiotherapy tasks. A question remai...

Denoising Diffusion-Weighted Images of Rectal Cancer Acquired on a 0.35 T Magnetic Resonance Imaging-Guided Linear Accelerator Using Singular Value Decomposition

Authors: Jacqueline M. Andreozzi, Tess Armstrong, Shiva Bhandari, John M Bryant, Jessica M Frakes, David J. Gladstone, Sarah E Hoffe, Kujtim Latifi, Arash Naghavi, Steven Nichols, Ibrahim M. Oraiqat, Russell Palm, Gage H. Redler, Stephen A Rosenberg, Joseph Weygand

Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Thayer School of Engineering, Dartmouth College, Department of Radiation Oncology, Ohio State University, Moffitt Cancer Center, Department of Radiation Oncology, Moffitt Cancer Center

Abstract Preview: Purpose: The MR-linac provides unique opportunities for integrating advanced imaging into radiotherapy workflows, but the lower sensitivity of systems like the 0.35T model can pose challenges for diff...

Detector Physics-Incorporated Diffusion Denoising Models for Digital Breast Tomosynthesis with Dual-Layer Flat Panel Detectors

Authors: Alexander Bookbinder, Matthew Tivnan, Xiangyi Wu, Wei Zhao

Affiliation: Stony Brook Medicine, Massachusetts General Hospital

Abstract Preview: Purpose: To investigate and benchmark a system-adaptive diffusion-based digital breast tomosynthesis (DBT) denoising model for a direct-indirect dual-layer flat panel detector (DI-DLFPD) with a k-edge...

Developing a Comprehensive Multi-Modal Framework for Population-Scale Liver Volumetry: Insights and Predictive Models

Authors: Mustafa Bashir, Diana Kadi, Kyle J. Lafata, Jacob A. Macdonald, Mark Martin, Yuqi Wang, Marilyn Yamamoto

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Electrical and Computer Engineering, Duke University, Department of Radiology, Duke Unversity

Abstract Preview: Purpose: To develop a high-throughput, automated-data-interrogation pipeline for integrating imaging and clinical information to identify key determinants of liver volume (LV), enabling population-sca...

Development and Validation of Patient-Specific 3D-Printed Electron Applicators for Precision Radiotherapy

Authors: Md. Jobairul Islam

Affiliation: Department of Radiation Oncology, Labaid Cancer Hospital and Super Speciality Centre

Abstract Preview: Purpose: Electron radiotherapy is an effective treatment for superficial tumors but requires field-shaping devices like electron applicators, which are labor-intensive to produce. This study aimed to ...

Development of a Visualization Tool for LET and Proton Spot Mapping for PB Treatment Planning

Authors: Chang Chang, Mohammad Kanber, Stephen Kenneth Northway

Affiliation: East Carolina University, California Protons Cancer Therapy Center, California Proton Cancer Therapy Center

Abstract Preview: Purpose:
Proton therapy treatment planning involves the consideration of unique physical quantities such as Linear Energy Transfer (LET) and spot location maps that do not exist in photon treatment...

Differential Hole-Size Lattice Patterns for Escalating SFRT Dose to Large, Deep-Seated, and Unresectable Masses

Authors: Joshua Misa, Damodar Pokhrel, William St. Clair

Affiliation: University of Kentucky, Department of Radiation Medicine

Abstract Preview: Purpose: Development of a novel spatially fractionated radiotherapy (SFRT) lattice deployment method featuring a large high-dose sphere at the tumor’s center, surrounded by smaller diameter spheres. W...

Direct Dose Verification in Liver SBRT Utilizing an Accumulative Daily CBCT Algorithm

Authors: Michael Buckstein, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Kaida Yang, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai

Abstract Preview: Purpose: Inter-fraction anatomic variations in liver SBRT can cause significant discrepancies between planned and delivered doses. We developed a CBCT-based accumulative algorithm to directly compare ...

Dosimetric Analysis of Plans Using X-Ray and X-γ-Ray Combination Strategy for Advanced Cervical Cancer Patients with Pelvic Lymph Node Metastasis

Authors: Yi Li

Affiliation: Department of Radiation Oncology, the First Affiliated Hospital of Xi'an Jiaotong University

Abstract Preview: Purpose: Advances in radiotherapy technology are crucial for improving cervical cancer (CC) treatment. This study explores a novel X-ray and γ-ray dual-modality radiation (TaiChiB) system, comparing i...

Dosimetric Assessment of Spatially Fractionated Radiation Therapy on Prostate Cancer Cases: Our Experience in Nsia-Luth Cancer Center, Lagos

Authors: Adebayo Abe, Samuel Olaolu Adeneye, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Sylvester Entonu, Muhammad Habeebu, Adedayo O. Joseph, Oluwaseyi Oderinde, Oluwadara Ojediran, Margaret Dideolu Taiwo

Affiliation: University of Ibadan, University of Lagos, Missouri University of Science and Technology, Purdue University, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre

Abstract Preview: Purpose:
Spatially Fractionated Radiation Therapy (SFRT) is an advanced radiotherapy technique designed to deliver highly heterogeneous radiation doses, aiming to optimize tumor control while minim...

Dosimetric Comparative Analysis of Modulated and Non Modulated Electron Bolus in Nasal Electron Therapy

Authors: Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Michael Leyva, Alejandro Rene Llanes Lopez, William Romaguera, Ranjini P. Tolakanahalli, Deborah Wang

Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute, Miami Cancer Institute, Baptist Health

Abstract Preview: Purpose: To evaluate whether a modulated electron bolus (MEB) technique improves both nominal and shifted dose distributions in nasal electron therapy as compared to a non‑modulated, uniform‑thickness...

Dual Energy Cone Beam Computed Tomography for Artifact Reduction and Enhanced Image Quality Using Existing Hardware in Radiation Therapy

Authors: Michael J. Choi, Vindu Wathsala Kathriarachchi, Christopher L. Nelson, Andrew P. Soderstrom, Yawei Zhang

Affiliation: The University of Texas MD Anderson Cancer Center, MD Anderson, UF Health Proton Therapy Institute

Abstract Preview: Purpose: Cone Beam Computed Tomography (CBCT) is widely used in image-guided radiation therapy for patient positioning. While kV photons offer high image contrast, they are prone to artifacts caused b...

Efficient FAST-Forward Planning Strategy for X-Ray Based Online Adaptive Radiotherapy

Authors: Prasanna Alluri, Mona Arbab, Xingzhe Li, Chang-Shiun Lin, Mu-han Lin, David D.M. Parsons, Asal Rahimi, Justin D. Visak, Narine Wandrey

Affiliation: UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX

Abstract Preview: Purpose: Intelligence-Optimization-Engine (IOE) v1.0 relied heavily on planner expertise and patient-specific IMRT beam arrangements, requiring frequent revisions. While VMAT workflows offered potenti...

Empowering Knowledge Transfer in Global Radiotherapy Planning: An Educational Case Study of Knowledge-Based Models in Nepal

Authors: Rita Buono, Elisabetta Cagni, Roberta Castriconi, Surendra Bahadur Chand, Marco Esposito, Claudio Fiorino, Valeria Landoni, Aldo Mazzilli, Eugenia Moretti, Lorenzo Placidi, Giulia Rambaldi Guidasci, Alessia Tudda

Affiliation: IRCCS San Raffaele Scientific Institute, Department of Advanced Technology, IRCCS Regina Elena National Cancer Institute, ASU FC Medical Physics, University Hospital of Parma AOUP, ICTP, B.P. Koirala Memorial Cancer Hospital, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Fatebenefratelli Isola Tiberina – Gemelli Isola

Abstract Preview: Purpose: To explore the feasibility and educational impact of transferring knowledge-based planning (KBP) models—developed using Italian breast radiotherapy data—to a Nepalese hospital, thereby demons...

Enhancing CNN-Based Brain Metastasis Detection in MRI By Integrating Locoregional 3D Deformation Technique

Authors: Minbin Chen, Ke Lu, Kaizhong Shi, Chunhao Wang, Chuan Wu, Zhenyu Yang, Fang-Fang Yin, Jingtong Zhao

Affiliation: The First People's Hospital of Kunshan, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, Department of Radiation Oncology, Duke Kunshan University

Abstract Preview: Purpose: MRI-based automatic detection of brain metastases is often challenged by the small size and subtle nature of metastases. This study aimed to develop a novel deep learning-based brain metastas...

Enhancing Daily QC for Photon-Counting CT: Incorporating 40 keV VMI Evaluations with the ACR CT Phantom

Authors: Lakshmi Ananthakrishnan, Xinhui Duan, Liqiang Ren, Gary Xu, Kuan Zhang, Yue Zhang

Affiliation: Department of Radiology, UT Southwestern Medical Center, Imaging Services, UT Southwestern Medical Center

Abstract Preview: Purpose: Daily quality control (QC) programs for diagnostic CT include water CT number (HU), standard deviation (SD), and visual artifact evaluations. At our institution, 70 keV virtual monoenergetic ...

Enhancing Dose Conformity in Halcyon SRS Plans: A Novel Approach Using Optimized Collimator Angles and Sub-Arcs.

Authors: David Chighvinadze, Chieh-Wen Liu, Sugandima Weragoda, Ping Xia

Affiliation: Cleveland Clinic Sandusky, Cleveland Clinic

Abstract Preview: Purpose: To explore the feasibility of using coplanar beams with collimator angle optimization for brain SRS plans with Halcyon system.
Methods: This study used a dataset of 26 patients with 2-3 br...

Enhancing T2-Weighted Brain MRI Resolution across Orientations Using AI-Based Volumetric Reconstruction

Authors: Mengqi Shen, Meghna Trivedi, Tony J.C. Wang, Andy (Yuanguang) Xu, Yading Yuan

Affiliation: Columbia University Medical Center, Dept of Med Hematology & Oncology, Data Science Institute at Columbia University, Columbia University Irving Medical Center, Department of Radiation Oncology, Columbia University Irving Medical Center

Abstract Preview: Purpose: T2-weighted (T2w) images are critical for identifying pathological changes due to their superior contrast in differentiating tissue types. However, they often lack detailed anatomical resolut...

Evaluating the Efficacy and Efficiency of Spine Treatment Using Diagnostic CT

Authors: Sunil Mani, Ilakiya Raghavendiran, Vasanthan Sakthivel, Skanda Kabilan Swamy

Affiliation: Edmond Santa Fe High School, Edmnd Deer Creek High, Cancer Specialists of North Florida, Advanced Medical Physics

Abstract Preview: Purpose: Purpose/Objective(s): To evaluate and validate the dose calculation and delivery accuracy for patients planned using diagnostic CT
Methods: A total of forty-two patients with palliative sp...

Evaluation of Target Localization Accuracy As a Function of CBCT Acquisition Speed

Authors: Kuan Ling Chen, Jiajin Fan, Maduka M. Kaluarachchi, Wei Nie

Affiliation: Inova Schar Cancer Institute

Abstract Preview: Purpose: This study evaluates the impact of CBCT acquisition speed on the accuracy of moving target alignment during image-guided radiotherapy. Additionally, the influence of target motion speed and r...

Evaluation of the Improvements of a New Leaf Model (Enhanced Leaf Model) for the Halcyon

Authors: Evan Barber, Gloria P. Beyer, Callum Hartley, Jordi Saez, Philip Wheeler

Affiliation: Department of Radiation Oncology, Hospital Clinic de Barcelona, Department of Radiotherapy Physics, Velindre University NHS Trust, Medical Physics Services, LLC

Abstract Preview: Purpose: To evaluate the Enhanced Leaf Model (ELM) in Eclipse v18 to the standard leaf model for the Halcyon multileaf collimator (MLC) using a measurement-based method.
Methods: The Halcyon’s doub...

GPU-Accelerated Beamlet and Full Dose Calculations for Efficient Radiation Therapy Planning

Authors: Girish Bal, Jan Kralj, Ayan Mitra, PhD, Ling Shao, Matjaz Subic, Yevgen Voronenko

Affiliation: RefleXion Medical, Cosylab

Abstract Preview: Purpose: This work enhances the efficiency of radiation therapy treatment planning by optimizing the beamlet dose matrix and full patient dose computations using GPU acceleration. The Collapsed-Cone C...

Generalizable 7T T1 Map Synthesis from 1.5T and 3T T1W MRI for High-Resolution MRI-Guided Radiation Therapy

Authors: Zachary Buchwald, Chih-Wei Chang, Zach Eidex, Hui Mao, Richard L.J. Qiu, Justin R. Roper, Mojtaba Safari, Hui-Kuo Shu, Xiaofeng Yang, David Yu

Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Emory University School of Medicine

Abstract Preview: Purpose: MRI-guided radiation therapy (MRgRT) benefits significantly from enhanced soft-tissue contrast and spatial resolution, which aid in accurately delineating tumors and organs at risk. Although ...

Glandular Dose Map in Voxelized Phantoms across Advanced Breast Imaging Modalities Obtained from Monte Carlo Simulations

Authors: Rodrigo T Massera, Sofia Giaccone Thomaz, Alessandra Tomal, Giovanna Tramontin

Affiliation: Universidade Estadual de Campinas. Instituto de Física Gleb Wataghin, Department of Imaging & Pathology, unit of Medical Physics & Quality Assessment, KU Leuven

Abstract Preview: Purpose: Monte Carlo simulations are increasingly used in breast dosimetry for their precision in estimating difficult-to-measure quantities, such as glandular dose. With ionizing radiation in breast ...

Gradient-Based Radiomics for Outcome Prediction and Decision-Making in Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR): A Preliminary Study

Authors: Michael Dohopolski, Jiaqi Liu, Hao Peng, Robert Timmerman, Zabi Wardak, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
This study introduces a gradient-based radiomics framework to enhance outcome prediction in Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR) for brain metastases...

Imaging Performance of Direct-Indirect Dual-Layer Flat-Panel-Detector Prototypes for Contrast-Enhanced Digital Mammography

Authors: Salman M. Arnab, Yves Chevalier, Samuel Gagné, Adrian F. Howansky, Luc Laperrière, Xiangyi Wu, Wei Zhao

Affiliation: Stony Brook Medicine, Analogic Canada

Abstract Preview: Purpose: A direct-indirect dual-layer flat-panel-detector (DI-DLFPD) is under development for patient motion artifact-free contrast-enhanced digital mammography (CEDM). DI-DLFPD comprises a direct fro...

Improved SNR and Estimation Accuracy for Deuterium-MRI Acquired with Chemical Shift Imaging at 7 Tesla

Authors: Muhammed AR Anjum, Andrew J. Fagan

Affiliation: Mayo Clinic

Abstract Preview: Purpose:
This study describes a novel post-processing method to boost image SNR for deuterium-MRI acquired using chemical shift imaging (CSI) at 7T. Deuterium MRI via exogenous administration of a ...

Improving Patient Safety with MRI Visible Laterality Markers

Authors: Ndey Badjan, Chris Beasley, Issack Boru, Josh Joyner, Erica Owenby, Scott H. Robertson, Nicholas Said

Affiliation: Duke University Health System

Abstract Preview: Purpose:
To design MRI-visible laterality markers to boost patient safety by minimizing errors in laterality and subsequent procedures.
Methods:
The markers were made using commercially avail...

Improving the Robustness of AI-Based Detection and Segmentation for Brain Metastasis By Optimizing Loss Function and Multi-Dataset Training

Authors: Omar Awad, Alfredo Enrique Echeverria, Issam M. El Naqa, Daniel Allan Hamstra, Yiding Han, Ryan Lafratta, Abdallah Sherif Radwan Mohamed, Piyush Pathak, Zaid Ali Siddiqui, Baozhou Sun, Vincent Ugarte

Affiliation: H. Lee Moffitt Cancer Center, Harris Health, Baylor College of Medicine

Abstract Preview: Purpose:
Accurate detection and segmentation of brain metastases are critical for diagnosis, treatment planning, and follow-up imaging but are challenging due to labor-intensive manual assessments ...

Initial Comparison of 3D CBCT Performance: New Mobile C-Arm Vs. O-Arm Unit

Authors: Wendy Siman, Wei Zhou

Affiliation: University of Colorado Anschutz Medical Campus, School of Medicine

Abstract Preview: Purpose:
To compare the image quality and radiation dose of 3D cone-beam CT modes of a mobile C-arm and an O-arm unit for intraoperative imaging.
Methods:
A 50-µm tungsten wire was imaged at ...

Intraoperative Dynamic Contrast-Enhanced Fluorescence Imaging in Quantifying Tissue Perfusion of Amputation Patients

Authors: Logan M. Bateman, Xu Cao, Jonathan T. Elliott, Lillian A. Fisher, Ida Leah Gitajn, Xinyue Han, Eric R. Henderson, Shudong Jiang, Jessica M. Sin, Yue Tang

Affiliation: Dartmouth College, Dartmouth-Hitchcock Medical Center

Abstract Preview: Purpose: Adequate tissue perfusion is essential for fracture healing and infection prevention, as it supplies oxygen, nutrients and antibiotics to the injury area. However, current methods of assessin...

Investigating Pitch Factor on Plan Quality in Patients Treated with Hippocampal Avoidance Whole Brain Radiotherapy Using Volo Ultra-Optimized Helical Tomotherapy Plans

Authors: Awens Alphonse, Nebi Demez, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Gagandeep Saini, Nishan Shrestha, Somol Sunny

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: This study examined the impact of varying the pitch factor in hippocampal-avoidance whole-brain (HP-WB) radiotherapy treatments, utilizing the newly introduced VOLO Ultra optimization for Hel...

Maximizing Integrated Treatment Planning Tools to Increase Automation for X-Ray-Based Adaptive Lung Sabr

Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, David D.M. Parsons, Justin D. Visak, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX

Abstract Preview: Purpose: Adaptive radiotherapy (ART) programs are resource-intensive due to their technical complexities, requiring highly skilled planners. Leveraging integrated automated treatment planning system (...

Mid-Range Planning for Efficient and Robust Proton Arc Therapy

Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Zi Yang, Kangning Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Delivery efficiency and robustness are critical in spot-scanning proton arc therapy (SPAT), yet the conventional use of redundant energy layers (ELs) prolongs switching times and reduces effi...

Multi-Path Deep Learning Model for Predicting Post-Radiotherapy Functional Liver Imaging in Patients with Hepatocellular Carcinoma

Authors: Smith Apisarnthanarax, Stephen R. Bowen, Sunan Cui, Jie Fu, Clemens Grassberger, Yulun He, Yejin Kim, Matthew J. Nyflot, Sharon Pai

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Washington, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Physics, University of Washington, University of Washington and Fred Hutchinson Cancer Center

Abstract Preview: Purpose: 99mTc-sulfur colloid SPECT imaging enables quantitative assessment of voxel-wise liver function in patients with hepatocellular carcinoma (HCC). Accurately predicting post-radiotherapy (RT) l...

Nausea, Heartburn, K-Edge Imaging: Pepto Bismol As a CT Contrast Agent

Authors: Magdalena Bazalova-Carter, Ross I. Berbeco, James Day, Xinchen Deng, Chelsea Amanda Saffron Dunning, Dianne M. Ferguson, Matthew W. Jacobson, Toby Morris, Marios Myronakis, Jericho Daniel O'Connell, Fides Schwartz, Jainil Shah, Aaron Sodickson

Affiliation: Brigham and Womens Hospital, University of Massachsetts Lowell and Dana-Farber Cancer Institute Boston, Medical Physics Department, Medical School, University of Thessaly, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, University of Washington, University of Victoria, Siemens Healthineers, Dana Farber/Brigham and Women's Cancer Center, Brigham and Women's Hospital

Abstract Preview: Purpose: While CT imaging has advanced with improved machine design, we propose further gains can be achieved by enhancing sensitivity to contrast agents. Current CT sensitivity is limited to 1% bismu...

On Dosimetric Water Equivalency of 3D Printed Materials

Authors: Emily Helen Hayes, Luke Maloney

Affiliation: University of Florida

Abstract Preview: Purpose: To determine the dosimetric water equivalency of polylactic acid (PLA) and commercial 3D printing resin using electron stopping power as a surrogate, for use in radiochromic film calibration ...

Predicting Prostate Cancer Recurrence Using an Atlas-Based Tumor Control Probability Model

Authors: Jeremy T. Booth, Martin Andrew Ebert, Robert Finnegan, Annette Haworth, George Hruby, Burhan Javed, Kazi Ridita Mahtaba, Leyla Moghaddasi, Yutong Zhao

Affiliation: Northern Sydney Cancer Centre, Royal North Shore Hospital, The University of Sydney, The University of Western Australia, Genesis Care, Rockhampton Hospital

Abstract Preview: Purpose:
To evaluate the efficacy of an atlas-based tumor control probability (TCP) model in predicting prostate cancer (PCa) recurrence by retrospectively integrating patient-specific primary radi...

Prior-Adapted Progressive Motion-Resolved CBCT Reconstruction Using a Dynamic Reconstruction and Motion Estimation Method

Authors: Hua-Chieh Shao, You Zhang, Ruizhi Zuo

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Cone-beam CT (CBCT) provides on-board patient anatomy for image guidance and treatment adaptation in radiotherapy. However, to compensate for respiration-induced anatomical motion, motion-res...

Prostate Dosimetric Comparison between Cyberknife and Radixact Modalities Using Precision and Raystation Planning Systems

Authors: Mireille Conrad, Cédric De Marco, Marie Fargier-Voiron, Maud Jaccard, Oscar Matzinger, Nicolas Joel Lionel Perichon

Affiliation: Clinique De Genolier

Abstract Preview: Purpose: The Accuray Synchrony real-time motion fiducial tracking solution allows for prostate stereotactic treatment on both Cyberknife and Radixact machines. In our radiotherapy department, two solu...

Protocol for In Vivo Dosimetry Using Myoslchip System: Characterization and Clinical Application

Authors: Jeremy S. Bredfeldt, Daniel W. Cail, Maria A. Czerminska, Cindy I. Hancox, David Hu, Benjamin Karasko, Claire Keun Sun Park

Affiliation: Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, Brigham and Women's Hospital, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School

Abstract Preview: Purpose: To develop a robust clinical protocol for in vivo dosimetry in radiotherapy using the myOSLchip Optically Stimulated Luminescent Dosimeter (OSLD) system by performing characterization and eva...

Quality and Performance Advantages of a Machine Learning-Assisted Framework for IMRT Fluence Map Optimization

Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang

Affiliation: Duke University Medical Center

Abstract Preview: Purpose: Gradient-based optimization is the standard approach for IMRT fluence map optimization (FMO). Recently, a machine learning (ML)-assisted framework using a one-layer neural network was propose...

Quantifying Respiratory Motion Effects in Lung Cancer Radiotherapy Using 4DCT Voxel Analysis

Authors: Chih-Chiang Chang, Chingyun Cheng, Ben Durkee, Minglei Kang, Elissa Khoudary, Yangguang Ma, Xuanqin Mou, YuFei Wang, Tengda Zhang, Wang Zhengda

Affiliation: Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, School of Software Engineering, Xi’an Jiaotong University, School of information and communications engineering, Faculty of electronic and information engineering, Xi’an Jiaotong University, Department of Medical Physics, Columbia University, University of Pennsylvania, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: This study presents a voxel-based analysis method based on deformable image registration to accurately quantify respiratory-induced motion and deformation of both targets and organs at risk (...

Quantitative Accuracy in Iodine Measurements and CT Numbers Using Standard and Ultra-High Resolution Photon-Counting CT in Coronary CTA

Authors: Afrouz Ataei, Victor Moy, Mark P. Supanich

Affiliation: Rush University

Abstract Preview: Purpose: To evaluate iodine quantification and CT number accuracy in coronary CT angiography (CTA) using standard and ultra-high resolution (UHR) modes of photon-counting CT (PCCT) across different do...

Quantitative Assessment of Iodine Detectability As a Function of Tissue Density, Thickness and Dose in Contrast-Enhanced Mammography

Authors: Jeffrey S. Nelson, Raj Kumar Panta, Megan K. Russ, Ehsan Samei

Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Contrast-enhanced mammography (CEM) enhances tumor detection by utilizing energy-dependent information from iodinated contrast agents. However, there is a lack of quantitative techniques to a...

Radial Waveguide Structures for Enhanced Power Transmission Efficiency in Dielectric Wall Accelerators

Authors: Julien Bancheri, Chau Giang Bui, David G Cooke, Christopher M Lund, Morgan J Maher, Jan P. Seuntjens, Jason Z Yuan

Affiliation: Princess Margaret Cancer Centre & University of Toronto, Medical Biophysics, University of Toronto, University of Toronto, Medical Physics Unit, McGill University, Department of Physics, McGill University

Abstract Preview: Purpose: The dielectric wall accelerator (DWA) offers a low-cost solution for proton therapy, using non-resonant waveguides to accelerate particles. Radial waveguides (RWGs), consisting of a dielectri...

Retrospective Study Using Avi Planner for Head and Neck Cancer Cases: Our Experience at Nsia-Luth Cancer Center, South - West Nigeria

Authors: Adebayo Abe, Samuel Olaolu Adeneye, Eben Aje, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Lilian Ekpo, Muhammad Habeebu, Adedayo O. Joseph, Charles S. Mayo, Noah Ndianaobong, Ikechi S Ozoemelam, Margaret Dideolu Taiwo, Godwin Uwagba

Affiliation: University of Michigan, University of Ibadan, University of Lagos, Missouri University of Science and Technology, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre, NSIA-LUTH Cancer Center

Abstract Preview: Purpose:
Head and neck cancers (HNC) present significant challenges in radiotherapy due to complex anatomy and the proximity to critical organs at risk (OARs). These challenges are compounded in na...

Small but Mighty: A Lightweight and Computationally Efficient Model for Deformable Image Registration

Authors: Hengjie Liu, Dan Ruan, Ke Sheng, DI Xu

Affiliation: Physics and Biology in Medicine, University of California, Los Angeles, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, Los Angeles

Abstract Preview: Purpose:
State-of-the-art deep learning-based deformable image registration often uses large, complex models directly adapted from computer vision tasks but achieves only comparable performance to ...

Tackling the Challenge of Multi-Target Metastases Treatment: Evaluation of Ethos Treatment Planning System

Authors: Avery Antes, Bulent Aydogan, Rama Chicfeh, Erik Pearson, Neslihan Sarigul

Affiliation: The University Of Chicago, The University of Chicago

Abstract Preview: Purpose: This study evaluates the performance of the Ethos Treatment Planning System (TPS) in managing oligometastatic cancer patients previously treated using multiple isocenter plans.
Methods: Th...

Tailor-TS System: Tailored Tumor Segmentation System with Facility-Specific Semi-Supervised Learning

Authors: Gong Vincent Hao, Daisuke Kawahara, Jokichi Kawazoe, Yuji Murakami, Ikuno Nishibuchi, Peiying Colleen Ruan, Daguang Xu, Dong Yang

Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University, NVIDIA

Abstract Preview: Purpose:
Accurate tumor segmentation in head and neck cancer is critical for effective treatment planning, but variability in practices across medical facilities poses challenges for standardizatio...

Task Specific Image Quality Assessment Using Spectral Photon-Counting CT.

Authors: Azza Mohamed Ahmed, Nadine Francis, Osama Khan, Nabil Maalej, Aamir Raja, Briya Tariq

Affiliation: Khalifa University

Abstract Preview: Purpose: The study aims to evaluate the task-specific diagnostic performance of spectral photon-counting CT (SPCCT) using application-specific phantoms.
Methods:
Parameters such as linearity res...

Transforming CT Technologist Training: Real-Time Feedback, Gamification, and Phantom-Based Education for Accurate Patient Positioning

Authors: Rebecca Lamoureux, Zahra (Zara) Razi, Zachary Whipps

Affiliation: University of New Mexico Hospital

Abstract Preview: Purpose: Patient mispositioning in CT imaging contributes to inconsistent radiation dose delivery and suboptimal image quality, impacting patient safety and diagnostic outcomes. This study evaluates a...

Tumor Density on Time-Weighted Mid-Position Images for Thoracic Tumors

Authors: Katrinus Keijnemans, Eric S. Paulson, An Tai

Affiliation: Department of Radiotherapy, University Medical Center Utrecht, Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Time-weighted mid-position images (MidPs), derived from four-dimensional computed tomography (4DCT) via deformable image registration (DIR), are frequently selected for treatment planning due...

Tumor Response to Catalytic Effect of Carbamide Peroxide to Megavoltage Radiodynamic Therapy with 5-Aminolevulinic Acid

Authors: Lili Chen, Dusica Cvetkovic, Chang Ming Charlie Ma, Dae-Myoung Yang

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose: Cytotoxicity caused by the reactive oxygen species (ROS) is a mechanism for treating cancer cells in radiation therapy. 5-aminolevulinic acid (5-ALA)-mediated radiodynamic therapy (RDT), whic...

Using Contrast-Enhanced Computed Tomography for Non-Invasive Lung Shunt Fraction Prediction in Yttrium-90 Radioembolization

Authors: Roger Eric Goldman, Adrianna Imani Johnson Carter, Talia Marx, Brahim Mehadji, Emilie Roncali, Catherine T. Vu

Affiliation: UC Davis, Department of Radiology, UC Davis Health

Abstract Preview: Purpose:
Accurate estimation of the Lung Shunt Fraction (LSF) is critical for yttrium-90 (90Y) radioembolization treatment planning to minimize risks of excessive lung irradiation due to arterio-ve...

Weakly Supervised Spatial Implicit Neural Representation Learning for 3D MRI-Ultrasound Deformable Image Registration in HDR Prostate Brachytherapy

Authors: Michael Baine, Yang Lei, Yu Lei, Ruirui Liu, Tian Liu, Jing Wang

Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center

Abstract Preview: Purpose: Accurate 3D deformable registration of MRI and ultrasound (US) is essential for real-time image guidance during high-dose-rate (HDR) prostate brachytherapy. However, MRI-US registration of th...