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Results for "estimation distributions": 17 found

A No-Reference Medical Image Quality Assessment Method Based on Automated Distortion Recognition Technology: Application to Preprocessing in MRI-Guided Radiotherapy

Authors: Jiayun Chen, Shengqi Chen, Yuan Tang, Zilin Wang, Guohua Wu, Jianan Wu

Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, School of Electronic Engineering, Beijing University of Posts and Telecommunications, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

Abstract Preview: Purpose:
To develop a novel no-reference image quality assessment (NRIQA) method for evaluating the effectiveness of image preprocessing in MRI-guided radiotherapy (MRIgRT), thereby enhancing clini...

AI-Based Real-Time Estimation of Patient Dose Distributions and Risk Based Tube Current Modulation

Authors: Marc Kachelriess

Affiliation: DKFZ Heidelberg, FS05

Abstract Preview: N/A...

Development of Preclinical Multiscale Dosimetry for Beta-Particle Emitting Radionuclide in Radiopharmaceutical Therapy

Authors: Adedamola Adeniyi, Bryan Bednarz, Malick Bio Idrissou, Reinier Hernandez, Ohyun Kwon, Brian W. Miller, Zachary S Morris, Maya Takashima, Jamey Weichert

Affiliation: Departments of Radiation Oncology and Medical Imaging, University of Arizona, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin–Madison, Department of Radiology, School of Medicine and Public Health, University of Wisconsin–Madison, Department of Human Oncology, School of Medicine and Public Health, University of Wisconsin–Madison

Abstract Preview: Purpose: As radiopharmaceutical therapy (RPT) becomes more prevalent in clinical applications, understanding dose-response relationships in the tumor microenvironment (TME) and normal tissues is essen...

Dosimetric Validation and Algorithmic Limitations of Pencil Beam Scanning Proton Therapy for Thin Chest-Wall Treatments

Authors: J Isabelle Choi, Meng Wei Ho, Isabel Lin, Hang Qi, Qi Zeng, Ajay Zheng

Affiliation: New York Proton Center, Scarsdale High School

Abstract Preview: Purpose: Proton therapy is a promising treatment modality for breast cancer due to its unique dosimetric advantage. Accurate dose calculation is critical to ensure effective treatment outcomes. The fo...

Estimation of Brain Tumor’s Intra-Fraction Movement during Radiosurgery Using Fiducial Markers on the Skin Surface – a Simulation Study

Authors: Damien C. Mathew, Brandon Hai Nguyen, Satwik Pani, Yoichi Watanabe

Affiliation: Minnespolis Radiation Oncology, Department of Radiation Oncology, University of Minnesota Medical School, Washington University

Abstract Preview: Purpose: To formulate a computational algorithm to quantify the tumor movement from the motion data of landmarks on the brain surface. To estimate the magnitude of tumor movement when the head makes a...

Evaluating Uncertainty Estimation Models for Clinical Integration of AI-Generated Radiotherapy Dose Distributions

Authors: Jacob S. Buatti, Kristen A. Duke, Malena Fassnacht, Neil A. Kirby, Parker New, Niko Papanikolaou, Arkajyoti Roy, Yuqing Xia, Michelle de Oliveira

Affiliation: The University of Texas San Antonio, UT Southwestern Medical Center, UT Health San Antonio

Abstract Preview: Purpose:
Quantifying and visualizing uncertainty is critical for building clinical trust in AI-generated dose distributions. This study evaluates Monte Carlo Dropout (MCD), Snapshot Ensemble (SE), ...

Evaluating the Radiological Safety of 64Cu-Macrin in PET/MRI Studies through Radiopharmaceutical Dosimetry

Authors: Alejandro Bertolet, Mislav Bobić, Carlos Huesa-Berral, Aileen O'Shea, Ralph Weissleder

Affiliation: Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Massachusetts General Hospital and Harvard Medical School

Abstract Preview: Purpose: To develop a pipeline for estimating the absorbed dose to various organs from positron emission tomography (PET) combined with magnetic resonance imaging (MRI). We use this pipeline to evalua...

Impact of Nanoscale TEM-Based and Simplified 3D Modeling Approaches on Monte Carlo Studies of Radiosensitization Effects in Gnp-Laden Cells

Authors: Sang Hyun Cho, Sandun Y. Jayarathna, Amrit Kaphle

Affiliation: The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: To assess the effectiveness of various nanoscale models of gold nanoparticle (GNP)-laden cells for Monte Carlo (MC) studies of GNP-mediated radiation dose enhancement/DNA damage.

Metho...

Improved SNR and Estimation Accuracy for Deuterium-MRI Acquired with Chemical Shift Imaging at 7 Tesla

Authors: Muhammed AR Anjum, Andrew J. Fagan

Affiliation: Mayo Clinic

Abstract Preview: Purpose:
This study describes a novel post-processing method to boost image SNR for deuterium-MRI acquired using chemical shift imaging (CSI) at 7T. Deuterium MRI via exogenous administration of a ...

Influence of Treatment Site on Lung Shunt Fraction Estimation in 90y-Radioembolization Planning: Comparison of Planar and SPECT Imaging-Based Quantification

Authors: Lukas M. Carter, Jazmin Schwartz

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Accurate lung shunt fraction (LSF) estimation is essential for the safety and efficacy of 90Y-radioembolization therapy. This study compares planar gamma camera imaging and tomographic SPECT-...

Mesh-Based Multiregion Model of Adult Human Kidneys for Dosimetric Evaluation of Radiopharmaceutical Therapy

Authors: John P. Aris, Wesley E. Bolch, Chansoo Choi, Carlos G. Colon-Ortiz, Robert Joseph Dawson, Abdul-Vehab Dozic, Amy M. Geyer, Harald Paganetti, Shreya P. Pathak, Julia D. Withrow

Affiliation: St. Luke's Health System, Massachusetts General Hospital, University of Florida

Abstract Preview: Purpose: The goal of this study was to enhance the accuracy of renal dosimetry in radiopharmaceutical therapy (RPT) by developing a more detailed and precise kidney model. In RPT, accurate dose estima...

Optimization of Impulsed Acquisition Protocols on 1.5T MRI Using Simulation-Based Bayesian Experimental Design for Cell Size Imaging

Authors: Yan Dai, Jie Deng, Xun Jia, Wen Li, Junzhong Xu

Affiliation: Johns Hopkins University, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiology, Vanderbilt University Medical Center, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Cell size is a vital parameter in evaluating the tumor microenvironment, including cell apoptosis and radiotherapy(RT)-induced immune cell infiltration. The IMPULSED(Imaging Microstructural P...

Organ Dose Estimation from Successive CBCT Imaging for Patients Undergoing Radiation Therapy for Prostate Cancer

Authors: Panagiotis Iliopoulos, Marios Myronakis, Kyriaki Theodorou

Affiliation: Medical Physics Department, Medical School, University of Thessaly

Abstract Preview: Purpose: To estimate individualized absorbed dose at Organs at Risk (OARs) from kV Cone Beam CT (CBCT) imaging in the pelvic area, prior radiotherapy, and assess excess risk for secondary malignancies...

Preclinical Assessment of 68ga-Dotatate As a Surrogate for 177lu-Dotatate Dose Distribution in Radionuclide Therapy

Authors: Payman Hejazi, Faraz Kalantari, Milad Peer-Firozjaei, Romina Pourhashem, Ehsan Tajikmansoury

Affiliation: Department of Radiobiology and Medical Physics, Babol University of Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Medical Physics, Semnan University of Medical Sciences, Department of Medical Physics, Semnan University of Medical Sciences, Semnan, Iran, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine

Abstract Preview: Purpose:
Pretreatment biodistribution imaging play a crucial role in optimizing tumors and organ absorbed doses estimation in radionuclide therapy. Surrogating radionuclides for more efficient trea...

Prostate Dosimetric Comparison between Cyberknife and Radixact Modalities Using Precision and Raystation Planning Systems

Authors: Mireille Conrad, Cédric De Marco, Marie Fargier-Voiron, Maud Jaccard, Oscar Matzinger, Nicolas Joel Lionel Perichon

Affiliation: Clinique De Genolier

Abstract Preview: Purpose: The Accuray Synchrony real-time motion fiducial tracking solution allows for prostate stereotactic treatment on both Cyberknife and Radixact machines. In our radiotherapy department, two solu...

Real-Time 3D Dose Verification for MR-Guided Online Adaptive Radiotherapy (ART) Via Geometry-Encoded Deep Learning Framework

Authors: Steve B. Jiang, Dan Nguyen, Chenyang Shen, Fan-Chi F. Su, Jiacheng Xie, Shunyu Yan, Daniel Yang, Ying Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Fast dose verification is essential for the safety and efficiency of MR-guided adaptive radiotherapy (ART) as patients anxiously waiting on the treatment couch. Conventional tools often requi...

Validation of an Open Source Automatic Segmentation Tool for Personalized Dosimetry

Authors: Klaus Bacher, Louise D'hondt, Jeff Rutten, Gwenny Verfaillie

Affiliation: Ghent University

Abstract Preview: Purpose: Manual organ segmentation is a very time-consuming but necessary process in personalized dosimetry. Automatic segmentation tools may alleviate this task. In this study the impact of automatic...