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Results for "features predicting": 45 found

A Hybrid Radiomics-Integrated Machine Learning Framework for Early Identification of Potential Radiation Pneumonitis in Lung Cancer Patients

Authors: Christos Ilioudis, Marios Myronakis, Sotirios Raptis, Kyriaki Theodorou

Affiliation: Medical Physics Department, Medical School, University of Thessaly, Department of Information and Electronic Engineering, International Hellenic University (IHU)

Abstract Preview: Purpose: This study presents a radiomics-driven, machine learning framework developed to predict the possibility of Radiation Pneumonitis (RP), as a side effect of radiation therapy in lung cancer pat...

A Multi-Omics Approach for Predicting Acute Hematologic Toxicity in Patients with Cervical Cancer Undergoing External-Beam Radiotherapy

Authors: Sijuan Huang, Yongbao Li

Affiliation: Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, Guangdong, 510060, China, Sun-Yat sen University Cancer Center

Abstract Preview: Purpose: Hematologic toxicity (HT) is one of the most prevalent treatment-related toxicities experienced by locally advanced cervical cancer (LACC) patients receiving radiotherapy (RT). This study aim...

A Radiomics and Dosomics-Based Approach for Predicting Hematologic Toxicity in Patients with Cervical or Endometrial Cancer

Authors: Yongrui Bai, Xuming Chen, Yong Liu, Xiumei Ma

Affiliation: Department of Radiation Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Abstract Preview: Purpose: Hematologic toxicity (HT) is a common complication in patients with cervical or endometrial cancer. This study aims to develop a precise predictive model for acute HT in patients with cervica...

A Two-Layer, Two-Task Prediction Model Based on 3D Imaging and Residual Networks for Mid-Chemoradiation Tumor Response Prediction on FDG PET for La-NSCLC

Authors: Stephen R. Bowen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Jing Sun, Jiajie Wang, Shouyi Wang, Faisal Yaseen, Xiaojing Zhu

Affiliation: Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Shanghai University of Electric Power, Fred Hutchinson Cancer Center, University of Texas at Arlington

Abstract Preview: Purpose: Accurate prediction of patient response to radiotherapy plays a crucial role in monitoring disease progression and assessing treatment efficacy, enabling clinicians to develop personalized th...

A Vision-Language Deep Learning Model for Predicting Survival Outcomes in Glioblastoma Patients

Authors: Zachary Buchwald, Chih-Wei Chang, Richard L.J. Qiu, Mojtaba Safari, Hui-Kuo Shu, Lisa Sudmeier, Xiaofeng Yang, David Yu, Xiaohan Yuan

Affiliation: Emory University and Winship Cancer Institute, Emory University, Georgia Institute of Technology, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: This study proposes a novel vision-language model (VLM) to predict survival outcomes in glioblastoma (GBM) patients. By integrating multimodal MRI data and clinical information, the proposed ...

AI-Driven Drug Discovery through an Interactive Analysis of Radiomics and Biological Insights in Glioblastoma

Authors: Nobuki Imano, Yuzuha Kadooka, Daisuke Kawahara, Misato Kishi, Yuji Murakami, Shumpei Onishi

Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Neurosurgery, Hiroshima University Hospital

Abstract Preview: Purpose: Radiomics has proven useful in predicting overall survival in glioblastoma (GBM) patients, but consistent molecular correlations remain unidentified, leaving its biological basis unclear. Thi...

Automated Framework for Predicting Tumour Growth in Vestibular Schwannomas Using Contrast-Enhanced T1-Weighted MRI

Authors: Mehdi Amini, Minerva Becker, Simina Chiriac, Alexandre Cusin, Dimitrios Daskalou, Ghasem Hajianfar, Sophie Neveu, Marcella Pucci, Yazdan Salimi, Pascal Senn, Habib Zaidi

Affiliation: Geneva University Hospital, Division of Radiology, Diagnostic Department, Geneva University Hospitals, Service of Otorhinolaryngology-Head and Neck Surgery, Department of Clinical Neurosciences, Geneva University Hospitals

Abstract Preview: Purpose: Personalized prediction of vestibular schwannoma (VS) tumour growth is crucial for guiding patient management decisions toward observation versus intervention. This study proposes an automate...

BEST IN PHYSICS THERAPY: Overcoming Challenges in Developing Machine Learning-Driven Acute Kidney Injury Predictive Models Using Non-Standard Emrs in Resource-Limited Settings

Authors: Yuanhan Chen, Ziqiang Chen, Qi Cheng, Feng Ding, Rui Fang, Shengwen Guo, Li Hao, Qiang He, Haiquan Huang, Yu Kuang, Xinling Liang, Yuanjiang Liao, Guohui Liu, Chen Lu, Qingquan Luo, Jing Sun, Yanhua Wu, Zhen Xie, Qin Zhang, Lang Zhou

Affiliation: South China University of Technology, Dongguan people's hospital, Sichuan Provincial People's Hospital, People’s Hospital of Xinjiang Uygur Autonomous Region, Second Hospital of Anhui Medical University, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangdong Easy Life Information Technology Co., Ltd, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Medical Physics Program, University of Nevada, Second Hospital of Jilin University, Chongqing Ninth People's Hospital

Abstract Preview: Purpose: Acute kidney injury (AKI) is a global healthcare issue with a rapid onset and severe consequences. Repeated measurement of serum creatinine (SCr) levels, a clinical standard of care, is cruci...

Binary Classification of Lymphedema in 3DCRT Patients Using Machine Learning on 3D Dose Distribution Data

Authors: Jee Suk Chang, Hojin Kim, Jin Sung Kim, Jaehyun Seok

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Integrative Medicine

Abstract Preview: Purpose: This study aims to leverage 3D dose distribution data to develop a machine learning model capable of accurately predicting lymphedema occurrence in patients undergoing 3D conformal radiation ...

CBCT-Based Radiomics of Head and Neck Cancer for Predicting Patient Toxicity to Radiotherapy

Authors: Rodrigo Delgadillo, Nesrin Dogan, Benjamin J. Rich, Stuart E Samuels, Levent Sensoy

Affiliation: University of Miami Sylvester Comprehensive Cancer Center

Abstract Preview: Purpose: Daily Cone beam CT (CBCT) images may be useful in detecting early morphological changes during head and neck cancer radiotherapy. The aim of this study was to evaluate the performance of CBCT...

CT Jacobian-Derived Texture-Based Radiomics Biomarker Predicts Future COPD Exacerbations

Authors: Jean Bourbeau, Jim Hogg, Miranda Kirby, Meghan Koo, Kalysta Makimoto, Wan Tan

Affiliation: Montreal Chest Institute of the Royal Victoria Hospital, McGill University Health Centre, Toronto Metropolitan University, Centre for Heart Lung Innovation, University of British Columbia

Abstract Preview: Purpose: Chronic obstructive pulmonary disease (COPD) exacerbations are burdensome to patients and healthcare systems. CT imaging-derived measures of emphysema and airway remodeling have been shown to...

Can Regional Radiomic Features from Pre-Treatment Computed Tomography Serve As Biomarkers for Predicting Radiation Pneumonitis?

Authors: David J. Carlson, Ming Chao, Tian Liu, Yong Hum Na, Kenneth E Rosenzweig, Robert Samstein, Lewis Tomalin

Affiliation: Icahn School of Medicine at Mount Sinai, Yale University School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: To investigate the potential of regional radiomic features extracted from five lung sub-lobes on pre-treatment CT as biomarkers for predicting radiation pneumonitis (RP) using machine learnin...

Construction and Application Study of a Deep Learning-Based Iscout-Guided Precision Radiotherapy Positioning Error Prediction Model for Breast Cancer

Authors: Fangfen Dong, Jiaming Li, Xiaobo Li, Weipei Wang, Zhixin Wang, Bing Wu, Benhua Xu, Yong Yang, Yifa Zhao

Affiliation: Department of Radiation Oncology, Fujian Medical University Union Hospital/Fujian Key Laboratory of Intelligent Imaging and Precision Radiotherapy for Tumors/Clinical Research Center for Radiology and Radiotherapy of Fujian Province (Digestive, Hematologi, Zhangpu County Hospital, School of Medical Imaging, Fujian Medical University

Abstract Preview: Purpose: To explore the construction and clinical application value of a deep learning-based positioning error prediction model, providing a reference for optimizing iSCOUT system-guided precision rad...

Early GU Toxicity Prediction in Prostate SBRT Using Delivered Dosimetry Via Long Short-Term Memory Model

Authors: Amar Kishan, Jun Lian, Yunkui Pang, Jonathan Pham, X. Sharon Qi, Michael Steinberg, Luca F Valle, Pew-Thian Yap

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of North Carolina at Chapel Hill

Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) is a highly effective treatment for prostate cancer, yet predicting genitourinary (GU) toxicity has primarily relied on planned dosimetry. This study inv...

Enhanced Prediction of Iroc Stereotactic Radiosurgery Phantom Audit Results with Treatment Parameters, Complexity Metrics, DVH, and Dosiomics Using Machine Learning

Authors: Lian Duan, Stephen F. Kry, Hunter S. Mehrens, Christine Peterson, Paige A. Taylor

Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center

Abstract Preview: Purpose: To develop predictive models for IROC SRS head phantom audits and to identify important factors influencing institutional performance.
Methods: The IROC SRS head phantom includes two TLDs ...

Enhanced Predictive Model for Toxicity and 3-Year Survival in HCC Patients Using Learning Health System Infrastructure and AI-Driven Statistical Profiling

Authors: Ameer Elaimy, Theodore Lawrence, Charles S. Mayo, Seyyedeh Azar Oliaei Motlagh, Benjamin S. Rosen

Affiliation: University of Michigan

Abstract Preview: Purpose: To analyze the impact of clinical features on short-term survival, toxicity, and poor outcomes in HCC patients treated with SBRT,using automated data aggregation and enhanced algorithms with ...

Enhancing Radiotherapy Planning with Machine Learning: Correlating Anatomical Features and Planning Difficulty to Guide Optimal Plan Design

Authors: Li Chen, Shouliang Ding, Xiaoyan Huang, Lecheng Jia, Hua Li, Hongdong Liu, Yanfei Liu, Zun Piao, Guangyu Wang

Affiliation: State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Shenzhen United Imaging Research Institute of Innovative Medical Equipment

Abstract Preview: Purpose: Optimal radiotherapy planning is challenging, influenced by anatomical factors such as surrounding organs and tumor characteristics, which complicate dose distribution and target coverage. Wh...

Evaluating Supervised Learning Models for Binary Classification of Radiomic Data in Predicting Head and Neck Cancer Treatment Outcomes

Authors: Theodore Higgins Arsenault, Kyle O'Carroll, Christian Erik Petersen, Alex T. Price, Meiying Xing

Affiliation: University Hospitals Seidman Cancer Center

Abstract Preview: Purpose: To assess the performance of various supervised learning models’ ability to predict binary classification of radiomic data for head and neck (H&N) cancer treatment outcomes.
Methods: Using...

Evaluation of Radiomic Feature Robustness in Quantitative CBCT Imaging for Radiotherapy of Prostate Cancer

Authors: Cem Altunbas, Farhang Bayat, Roy Bliley, Brian Kavanagh, Uttam Pyakurel, Tyler Robin, Ryan Sabounchi

Affiliation: Department of Radiation Oncology, University of Colorado School of Medicine, Taussig Cancer Center, Cleveland Clinic

Abstract Preview: Purpose: The use of image features extracted from serial CBCT images to assess radiotherapy response and toxicity is an active research area. However, poor image quality often compromises reliability ...

Feasibility Study of Deep Learning-Based MRI-to-PET Generation for Rectal Cancer: Overall Survival Prediction and Pathological Complete Response Assessment

Authors: Weigang Hu, Zhenhao Li, Jiazhou Wang, Xiaojie Yin, Zhen Zhang

Affiliation: Fudan University Shanghai Cancer Center

Abstract Preview: Purpose:
This study aims to develop and validate a novel deep learning method to generate synthetic PET images for rectal cancer from MRI data. By incorporating metabolic information from the synth...

Gaze Angle Selection in Proton Therapy for Ocular Tumors with Machine Learning

Authors: Ling Chen, Alexei V. Trofimov, Yi Wang, Dufan Wu

Affiliation: Massachusetts General Hospital, MGH

Abstract Preview: Purpose:
Selecting gaze angles of the eye is an important part of set-up of proton therapy for ocular tumors, ensuring that the treatment beam could irradiate the tumor while maximally sparing impo...

Identification of Potential Patients for Resimulation and Adaptive Planning By Machine Learning

Authors: Mark Ashamalla, Renee Farrell, Jinkoo Kim, Kartik Mani, Xin Qian, Samuel Ryu, Yizhou Zhao

Affiliation: Stony Brook Medicine, Stony Brook University Hospital

Abstract Preview: Purpose: Adaptive planning is increasingly used in head and neck radiation therapy due to factors like tumor response or changes in patient anatomy. However, methods such as resimulation or offline re...

Implementing a Learning-to-Optimize Machine Learning Framework to Accelerate VMAT Treatment Planning Optimization for Prostate Cancer

Authors: Ara Alexandrian, Sadiki Daniel

Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center

Abstract Preview: Purpose: To develop a learning-to-optimize machine learning model that accelerates optimization in VMAT treatment planning by training on prostate patient data.
Methods: A treatment plan dataset of...

Inter-Machine Harmonization in Echocardiographic Videos for Predicting Left Ventricular Ejection Fraction

Authors: Akihiro Haga, Ren Iwasaki, Kenya Kusunose, Makoto Miyake, Kenji Moriuchi, Yasuharu Takeda, Hidekazu Tanaka, Hirotsugu Yamada

Affiliation: Department of Cardiovascular Medicine, Nephrology, and Neurology Graduate School of Medicine, University of the Ryukyus, Graduate School of Biomedical Sciences, Tokushima University, Tokushima university, Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Department of Cardiology, Tenri Hospital, Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Division of Heart Failure, Department of Heart Failure and Transplant, National Cerebral and Cardiovascular Center

Abstract Preview: Purpose: Device dependency is a significant challenge in medical AI, potentially limiting generalization performance. This study aimed to develop a robust deep learning model for predicting left ventr...

Interpretable Deep Learning Predicts Metastasis-Free Survival (MFS) from Conventional Imaging for Oligometastatic Castration-Sensitive Prostate Cancer (omCSPC) Using Multi-Modality PSMA PET and CT Imaging.

Authors: Yufeng Cao, Luigi Marchionni, William Silva Mendes, Cem Onal, Lei Ren, Amit Sawant, Nicole L Simone, Philip Sutera, Phuoc Tran

Affiliation: University of Maryland School of Medicine, 9Department of Radiation Oncology, Thomas Jefferson University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, University of Maryland, Baltimore, Baskent University Faculty of Medicine, Department of Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine, Maryland University Baltimore, 8Department of Pathology and Laboratory Medicine, Weill Cornell Medicine

Abstract Preview: Purpose: This study aims to predict 2-yr Metastasis-free survival (MFS) for oligometastatic castration-sensitive prostate cancer (omCSPC) patients treated by metastasis-directed therapy (MDT) by devel...

Investigating the Multimodal Fusion Techniques to Improve Prediction Accuracy of Biochemical Recurrence of Prostate Cancer

Authors: Clint Bahler, Ruchika Reddy Chimmula, Harrison Louis Love, Oluwaseyi Oderinde, Courtney Yong

Affiliation: Purdue University, Department of Urology, Indiana University School of Medicine, Advanced Molecular Imaging in Radiotherapy (AdMIRe) Research Laboratory, School of Health Sciences, Purdue University

Abstract Preview: Purpose: Prostate cancer (PCa) is a common malignancy in men, and predicting biochemical recurrence (BCR) is crucial for guiding treatment decisions. Integrating multimodal data, including clinical, i...

Key Tumor Volume Zones for Advancing the Radiomics-Based Distant Recurrence Prediction

Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder

Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida

Abstract Preview: Purpose: Radiomics feature-based model for predicting distant recurrence can potentially provide critical insight for clinical decision-making and assistance in treatment strategies. This study focuse...

Knowledge-Based Three-Dimensional Dose Prediction for High Dose Rate Prostate Brachytherapy

Authors: Mojtaba Behzadipour, Suman Gautam, Tianjun Ma, Ikchit Singh Sangha, Bongyong Song, William Song, Kumari Sunidhi

Affiliation: UC San Diego, Virginia Commonwealth University

Abstract Preview: Purpose: This study aims to develop a knowledge-based voxel-wise dose prediction system using a convolutional neural network (CNN) for high-dose-rate (HDR) prostate brachytherapy and to evaluate its p...

LLM-Enhanced Multi-Modal Framework for Predicting Pain Relief of Stereotactic Body Radiotherapy for Spine Metastases Using Clinical Factors and Imaging Reports

Authors: John Byun, Steven D Chang, Mingli Chen, Cynthia Chuang, Xuejun Gu, Melanie Hayden Gephart, Yusuke Hori, Hao Jiang, Mahdieh Kazemimoghadam, Fred Lam, Gordon Li, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang, Qingying Wang, Zi Yang, Xianghua Ye, Kangning Zhang

Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Accurate prediction of pain relief is crucial in determining the clinical effectiveness of Stereotactic body radiotherapy (SBRT) regimen for spine metastases. We propose a deep-learning frame...

Lymph Node Malignancy Prediction in Head and Neck Cancer Using a Graph Neural Network

Authors: Liyuan Chen, Meixu Chen, Bowen Jing, Sepeadeh Radpour, Erich Josef Schmitz, David Sher, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Prospective clinical trials have shown that involved nodal radiation therapy (INRT) can substantially improve patients’ quality of life without increasing the risk of elective nodal failure. ...

Lymphocytic Feature Characterization Using a Deep Learning Algorithm on Post-Radiation Lymph Nodes

Authors: Rico Castillo, Katherine Gonzalez, Casey C. Heirman, Kyle J. Lafata, Casey Y. Lee, Xiang Li, Yvonne M Mowery, Yvonne M Mowery, Daniel Murphy, Allison Pittman, Ashlyn G. Rickard

Affiliation: Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh

Abstract Preview: Purpose: To evaluate the ability of a deep learning model to identify pathomic features in lymph nodes of preclinical head and neck squamous cell carcinoma (HNSCC) models as surrogates for predicting ...

MRI Radiomics-Based Machine Learning Model for Predicting BNCT Treatment Response in Glioblastoma

Authors: Huang Chi-Shiuan, Wu Chih-Chun, Hui-Yu Cathy Tsai, Chen Yan-Han, Chen Yi-Wei, Pan Yi-Ying

Affiliation: Institute of Nuclear Engineering and Science, National Tsing Hua University, Taipei Veterans General Hospital, Tri-Service General Hospital

Abstract Preview: Purpose:
This study aims to develop and validate a machine learning (ML) model based on MRI-derived radiomic features to predict progressive disease (PD) in glioblastoma (GBM) patients four months ...

Muilt-Instance Learning Model with 2D and 3D Features Representation and Transformer-Based Prediction for FDG PET Tumor Chemoradiation Response of La-NSCLC

Authors: Stephen R. Bowen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Jiajie Wang, Shouyi Wang, Faisal Yaseen, Han Zhou

Affiliation: Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Fred Hutchinson Cancer Center, University of Texas at Arlington

Abstract Preview: Purpose: Predicting the effects of the spatial-temporal tumor response to chemoradiation can assist in adjusting radiation dose and support clinical decision-making in radiotherapy. A multi-instance l...

Multimodal Data Integration with Machine Learning for Predicting PARP Inhibitor Efficacy and Prognosis in Ovarian Cancer

Authors: Qianxi Ni, Xian Xiong

Affiliation: The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University

Abstract Preview: Purpose:
Poly(ADP)-ribose polymerase inhibitors (PARPi) have brought a significant breakthrough in the maintenance treatment of ovarian cancer. However, beyond BRCA mutation/HRD, the direct impact ...

Multimodal Framework for Predicting Radiation-Induced Severe Acute Esophagitis in Esophageal Cancer

Authors: Yeona Cho, Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Jihun Kim, Jin Sung Kim, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu

Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, Memorial Sloan Kettering Cancer Center, Yonsei University

Abstract Preview: Purpose: We hypothesized that combining clinical, imaging, and radiotherapy dose-distribution features could increase predictive model accuracy in radiation-induced severe acute esophagitis (SAE) in e...

Nomogram Based on Interpretable Multiregional Radiomics of Cone-Beam Breast CT and Clinicopathologic Features for Predicting FISH Status in HER2 2+ Breast Cancer to Differentiate HER2-Low from -Positive: A Multi-Center Study

Authors: Keyi Bian, Marco Caballo, Wenxiu Guo, Haijie Li, Jiao Li, Aidi Liu, Yue Ma, Ioannis Sechopoulos, Yafei Wang, Yaopan Wu, Zhaoxiang Ye, Yuwei Zhang, Yueqiang Zhu, Daan van den Oever

Affiliation: Radboud University Medical Center, Tianjin Medical University Cancer Institute & Hospital, Sun Yat-Sen University Cancer Center

Abstract Preview: Purpose: To develop and validate a nomogram integrating intra- and peritumoral radiomics of contrast-enhanced cone-beam breast CT (CE-CBBCT) and clinicopathologic features for predicting fluorescence ...

Precision Radiotherapy Dose Prediction Using Foundation Model-Augmented Learning

Authors: Hilary P Bagshaw, Mark K Buyyounouski, Xianjin Dai, PhD, Praveenbalaji Rajendran, Lei Xing, Yong Yang

Affiliation: Department of Radiation Oncology, Stanford University, Massachusetts General Hospital, Harvard Medical School

Abstract Preview: Purpose: Artificial intelligence (AI)-driven methods have transformed dose prediction, streamlining the automation of radiotherapy treatment planning. However, traditional approaches depend exclusivel...

Predicting Brain V60% in Linac-Based Single-Isocenter-Multiple-Targets (SIMT) Stereotactic Radiosurgery Using Machine Learning

Authors: John Ginn, Zhuoyun Huang, Yongbok Kim, Ke Lu, Chunhao Wang, Yibo Xie, Zhenyu Yang, Jingtong Zhao

Affiliation: Duke University, Duke Kunshan University

Abstract Preview: Purpose: This study aims to develop and validate a machine learning model for predicting V60%, a critical dosimetric metric in LINAC-based Single-Isocenter-Multiple-Targets (SIMT) stereotactic radiosu...

Predicting Hematologic Toxicity in Advanced Cervical Cancer Patients Using Interpretable Machine Learning Models Based on Radiomics and Dosimetrics

Authors: Qianxi Ni, Qionghui Zhou

Affiliation: The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University

Abstract Preview: Purpose:
This study aims to develop and evaluate interpretable machine learning models that use radiomic and dosimetric features to predict HT in advanced cervical cancer patients.
Methods:
R...

Predicting Hormone Receptor Status in Breast Cancer Using Mammographic and Sonographic Data and Machine Learning Models

Authors: Zahra Bagherpour, Manijeh Beigi, Pedram Fadavi, Faraz Kalantari, Moghadaseh Khaleghibizaki, Hengameh Nazari, Mojtaba Safari, Sepideh Soltani

Affiliation: Department of Radiation Oncology, School of Medicine, Iran University of Medical Sciences, Department of Radiation Oncology, School of Medicine, Emory University and Winship Cancer Institute, Department of Radiation Oncology, Iran University of Medical Sciences, University of Arkansas for medical sciences, Department of Radiation physics, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences

Abstract Preview: Purpose: This study aims to evaluate whether readily available mammographic and sonographic data, combined with machine learning (ML) models, can predict critical molecular factors (ER, PR, HER2) in b...

Predicting Proton Therapy Dose Delivery Accuracy: A Machine Learning Approach Using Iroc’s Proton Phantom Data

Authors: Lian Duan, Stephen F. Kry, Hunter S. Mehrens, Paige A. Taylor

Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center

Abstract Preview: Purpose: To develop a machine learning model for predicting dose delivery accuracy and identifying its key factors in IROC’s proton phantom program.
Methods: IROC’s proton QA program has six proton...

Prediction of Vertebral Compression Fracture after Stereotactic Body Radiotherapy for Spinal Metastases Using Clinical, Radiomic and Dosiomic Features

Authors: Yukio Fujita, Syoma Ide, Kei Ito, Tomohiro Kajikawa, Satoshi Kito, Keiko Murofushi, Yujiro Nakajima, Yuhi Suda, Kentaro Taguchi, Naoki Tohyama, Fumiya Tsurumaki

Affiliation: Komazawa University Graduate School, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Department of Radiology, Kyoto Prefectural University of Medicine

Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) for spine metastases is more effective for pain relief and local control than conventional radiotherapy. However, it is associated with vertebral compres...

To Investigate the Utility of Magnetic Resonance Imaging (MRI)-Based Radiomics for Predicting Tumor Response and Adverse Effects, Specifically Gastrointestinal (GI) Toxicity, in Cervical Cancer Patients Undergone Radiotherapy.

Authors: Issam M. El Naqa, Kurukulasuriya Ruwani Fernando, Himani Himani, Vivek Kumar, Arun Oinam, Manju Sharma

Affiliation: Panjab University, Moffitt Cancer Center, H. Lee Moffitt Cancer Center, Post Graduate Institute of Medical Sciences, University of California San Francisco

Abstract Preview: Purpose: To investigate the utility of Magnetic Resonance Imaging (MRI)-based radiomics for predicting tumor response and adverse effects, specifically gastrointestinal (GI) toxicity, in cervical canc...

Ukan Architecture for Voxel-Level Dose Prediction in Radiotherapy

Authors: Lu Jiang, Ke Sheng

Affiliation: Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose:
Conventional radiotherapy treatment planning is guided by a set of generic objectives that are unspecific to patient anatomy. Treatment planning thus heavily relies on the planner’s experi...

Using Bayesian Analysis to Quantify the Impact of Clinical and Dosimetric Features for Predicting Swallowing Dysfunction in Oropharyngeal Cancer after Radiotherapy

Authors: Matthew D Blackledge, Christopher M. Nutting, Anju Mohanan Kaimal, Justine Tyler, Konstantinos Zormpas-Petridis

Affiliation: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Institute of Cancer Research, The Royal Marsden NHS Foundation Trust, The Institute of Cancer Research

Abstract Preview: Purpose: Swallowing dysfunction (dysphagia) is a common side effect of radiotherapy for oropharyngeal cancer, significantly affecting patient's quality of life. This study aims to investigate the rela...