Authors: Sorour Hosseini, YuHuei Jessica Huang, Thomas Boyd Martin, Geoffrey S. Nelson, Nicholas Pierre Nelson, Hui Zhao
Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah
Abstract Preview: Purpose: To evaluate image quality—including noise, contrast-to-noise ratio (CNR), uniformity, and low-contrast visibility (LCV)—on the HyperSight and TrueBeam cone-beam computed tomography (CBCT) pla...
Authors: Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) reduces imaging time and dose but suffers from under-sampling artifacts. 2D–3D deformable registration addresses this problem by estimating LA-CBCTs from defor...
Authors: Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Joseph Shields, Christopher Tyerech
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pennsylvania, UPMC
Abstract Preview: Purpose: HyperSight is a new platform for image-guided radiation therapy, offering advanced reconstruction algorithms, a large field-of-view, and rapid acquisition times. To validate the performance o...
Authors: Mojtaba Behzadipour, Siyong Kim, Mitchell Polizzi, Richard R. Wargo, Lulin Yuan
Affiliation: VCU Health - Department of Radiology, Virginia Commonwealth University
Abstract Preview: Purpose:
The purpose of this study is to develop a method for generating missing tissue in CT scans of patients with large body sizes, where the field of view (FOV) of the scanner fails to capture ...
Authors: Hilary P Bagshaw, Mark K Buyyounouski, Cynthia Fu-Yu Chuang, Yu Gao, Dimitre Hristov, Lianli Liu, Lawrie Skinner, Lei Xing
Affiliation: Department of Radiation Oncology, Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose:
MR-guided radiation therapy has introduced a significant leap in cancer treatment by allowing adaptive treatment. The low-field MR-guided system predominantly uses the TrueFISP sequence, w...
Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Maximilian Stephen Meineke, Runhe Tan
Affiliation: The James Cancer Center, The Ohio State University, The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: The response of healthy vasculature due to radiation treatments is an underexplored area of radiation oncology. Understanding the impact of radiation on veins could advance treatment optimiza...
Authors: Petr Bruza, Jeremy Eric Hallett, Brian W Pogue
Affiliation: Thayer School of Engineering, Dartmouth College, University of Wisconsin - Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: Cherenkov imaging is a powerful tool for localizing entrance and exit dose during radiotherapy treatment. The current implementation uses an intensified-CMOS (iCMOS) camera allowing for high-...
Authors: Quan Chen, Xue Feng, Chunhui Han, Gaofeng Huang, Trevor Ketcherside, Yi Lao, Yun Rose Li, An Liu, Bo Liu, Kun Qing, William T. Watkins
Affiliation: Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, City of Hope National Medical Center, Mayo Clinic Arizona, Carina Medical LLC
Abstract Preview: Purpose: New treatment platforms such as Ethos (Varian Medical Systems) allow the introduction of multi-modal imaging into adaptive radiotherapy workflow to facilitate an up-to-date view of patients’ ...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski, Huanyi Zhou
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose: A new CT configuration utilizing a multiple X-ray-source array (MXA) is under development to mitigate cone-beam (CB) artifacts in single-rotation wide coverage imaging. We investigate the sam...
Authors: Peter Balter, Kristy K. Brock, Clifton David Fuller, Tze Yee Lim, James Long, Brigid A. McDonald, Androniki Mitrou, Andrew J. Schaefer, Stina Svensson
Affiliation: The University of Texas MD Anderson Cancer Center, RaySearch Laboratories, Rice University, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences
Abstract Preview: Purpose: CBCT-based accumulated dose can provide up-to-date dose information on responding anatomy. To optimize resources, it is necessary to determine how many scans provide adequate information for ...
Authors: Rachael Blair, Les Butler, Lillian Dickson, Kyungmin Ham, Charles Hartman, Kenneth (Kip) Matthews, Corinne Vanya
Affiliation: Louisiana State University, University of Minnesota, Refined Imaging LLC, Center for Advanced Microstructures and Devices
Abstract Preview: Purpose:
To develop and evaluate an x-ray interferometry system (XIS) for low-dose, high-sensitivity diagnostic imaging of lung diseases such as chronic obstructive pulmonary disease (COPD), asthma...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Iowa, Iowa Health Care
Abstract Preview: Purpose: In proton therapy, the substantial size of the gantry introduces sag, causing the proton isocenter to drift as a function of gantry angle. While the scanning magnets correct the beam’s isocen...
Authors: Jeremy Eric Hallett, Aubrey Parks, Brian W Pogue
Affiliation: University of Wisconsin - Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: Cherenkov imaging visualizes radiotherapy beams, assuming emission is proportional to deposited dose. However, attempts for Cherenkov as a quantitative dose estimation have been unsuccessful ...
Authors: Jacinta E. Browne, Tzu Cheng Chao, Ajit Deveraj, Ece Ercan, Tim Leiner, Alessio Perazzolo, Michal Povazan, Jouke Smink, Camilla Vita, Spencer Waddle, Dinghui Wang
Affiliation: Università Cattolica del Sacro Cuore, Philips Healthcare, Mayo Clinic
Abstract Preview: Purpose:
In recent years, mid-field MRI has shown promise to meet the technical demands of cardiac imaging1. Mid-field strengths offer advantages to CMR due to shorter T1-relaxation times, lower sp...
Authors: Krystal M. Kirby, Aliasghar Rohani, Christopher W. Schneider, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center, Louisiana State University, Baton Rouge, Louisiana
Abstract Preview: Purpose: Accurate treatment delivery in MR-guided radiotherapy (MRgRT) systems requires consistent imaging quality assurance (QA) to assess MR image quality. However, standard QA phantoms have limited...
Authors: Laura I. Cervino, Karen Episcopia, Hsiang-Chi Kuo, Sangkyu Lee, Seng Boh Gary Lim, Shih-Chi Lin, Grace Tang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: This study evaluated the performance of the HyperSight Cone-Beam Computed Tomography (CBCT) system on a TrueBeam C-arm LINAC (TB) and two Ethos ring-gantry LINACs (ES) for adaptive radiation ...
Authors: Julien Forthomme, Carolina Llina Fuentes, Valentin Hamaide, Lucian Hotoiu, Rudi Labarbe, Rasmus Nilsson, Arnaud Pin, Francois Vander Stappen, Erik Traneus
Affiliation: RaySearch Laboratories AB, Ion Beam Applications SA
Abstract Preview: Purpose: Conformal FLASH achieves ultra-high-dose-rate (UHDR) proton therapy (>40 Gy/sec) by scanning a mono-energetic pencil beam through accessories (range shifter, Conformal Energy Modulator, apert...
Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: The dependence of CT number on position in the field-of-view (FOV) imposes challenges in radiotherapy treatment planning. This study aims to decrease this dependence using photon counting det...
Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: To assess the dependency of CT numbers on position in the field-of-view (FOV) using single-energy (SE) and dual-energy (DE) images and energy-integrating detector (EID) and photon-counting de...
Authors: Imad M. Ali, Nesreen Alsbou, Sakeeneh Majeed
Affiliation: University of Central Oklahoma, University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: to design and assess a microwave imaging system equipped with multiple antennas for generating high-resolution 3D images of phantom models that simulate abdominal, thoracic, and brain tissues...
Authors: Mohammed Alzaabi, Owen Thomas Dillon, Julia Johnson, Andrew Kanawati, Tess Reynolds, Ann Yan
Affiliation: Westmead Hospital, Image X Institute, Faculty of Medicine and Health, The University of Sydney, Khalifa University
Abstract Preview: Purpose: To develop a physiological carotid artery phantom and Bayesian geometric calibration method to examine the feasibility of extended field-of-view interventional CBCT artery imaging using a mul...
Authors: Leshan Sun, Liangzhong Xiang, Yifei Xu, Yuchen Yan
Affiliation: University of California, Irvine
Abstract Preview: Purpose: X-ray Acoustic Computed Tomography (XACT) is a transformative innovation in medical imaging, overcoming the limitations of conventional X-ray techniques. It introduces new possibilities in cl...
Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: Accurate delineation of the urethra is critical for optimizing tumor control and minimizing urethral toxicity in prostate stereotactic body radiation therapy (SBRT). The purpose of this study...
Authors: Nema Bassiri, Kristen A. Duke, Neil A. Kirby, Thomas Wilson Klender, Christien Kluwe, Niko Papanikolaou, Holly Paschal, Karl H. Rasmussen, Daniel L. Saenz, Michelle de Oliveira
Affiliation: Miami Cancer Institute, University of Texas HSC San Antonio, UT Health San Antonio
Abstract Preview: Purpose: Determine the practical usability for three phantoms to be used with the ExacTrac Dynamic thermal imaging system. Thermal-guided imaging can be used for inter and intra motion management, pat...
Authors: Claus Belka, Stefanie Corradini, George Dedes, Nikolaos Delopoulos, Christopher Kurz, Guillaume Landry, Ahmad Neishabouri, Domagoj Radonic, Adrian Thummerer, Niklas Wahl, Fan Xiao
Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, LMU Munich, Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), National Center for Radiation Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO)
Abstract Preview: Purpose: In MR-guided online adaptive radiotherapy, MRI lacks tissue attenuation information necessary for accurate dose calculations. Instead of using deep learning methods to generate synthetic CT i...
Authors: Jochen Cammin, Shifeng Chen, Arun Gopal, Kai Huang, Jason K Molitoris, Amit Sawant, Kai Wang
Affiliation: University of Maryland, Department of Radiation Oncology, University of Maryland School of Medicine, Maryland University Baltimore, Department of Radiation Oncology, University of Maryland Medical Center
Abstract Preview: Purpose: The HyperSight CBCT optional feature on Varian TrueBeam linacs offers a larger field-of-view, improved Hounsfield units (HU) accuracy, and overall improved image quality, including metal arti...
Authors: Ramesh Boggula, Jay W. Burmeister
Affiliation: Wayne State University, Karmanos Cancer Center, Gershenson ROC, Wayne State University School of Medicine
Abstract Preview: Purpose: This study evaluated the performance of a hybrid Compton camera for real-time imaging during the administration of Lu-177-based radiopharmaceuticals, including Pluvicto and Lutathera. The aim...
Authors: Oluyemi Bright Aboyewa, KyungPyo Hong, Daniel Kim
Affiliation: Department of Radiology, Northwestern University
Abstract Preview: Purpose: While non-Cartesian MRI is desirable for fast imaging with high spatial resolution and robustness to motion, it requires long post-processing times. Preconditioning with an adequate density c...
Authors: Doris Dimitriadis/Dimitriadou, Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Noor Mail, Adam Olson, Tyler Wilhite
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, UPMC
Abstract Preview: Purpose: The goal of the HyperSight® offline adaptive-workflow is to create a methodical approach to adaptive-radiotherapy (ART) that considers modifications in patient setup and anatomy. Through effi...
Authors: Richard Dortch, Thammathida Ketsiri, Zhiqiang Li, Shiv P. Srivastava
Affiliation: Barrow Neurological Institute, Dignity Health Cancer Institute, St. Joseph's Hospital & Medical Center
Abstract Preview: Purpose: Imaging the spinal cord post-surgery is challenging due to metal surgical implants, which induce signal loss and geometric distortions. Together, this hinders the visualization of the spinal ...
Authors: Saree Alnaghy, Owen Thomas Dillon, Sean P Hood, Paul J. Keall, Ricky O'Brien, Tess Reynolds
Affiliation: Image X Institute, Faculty of Medicine and Health, The University of Sydney, University of Wollongong, Medical Radiations, School of Health and Biomedical Sciences, RMIT University
Abstract Preview: Purpose: Photon Counting Detectors (PCDs) have been demonstrated to improve resolution, contrast and lesion detectability in fan-beam CT. There is naturally a desire to bring these improvements to Con...
Authors: Ciprian Catana
Affiliation: Massachusetts General Hospital
Abstract Preview: N/A...
Authors: Gregory J Bootsma, Tunok Mondol
Affiliation: University Health Network, Princess Margaret Cancer Center
Abstract Preview: Purpose:
To evaluate the impact of prototype fluence field modulation (FFM) cone-beam CT (CBCT) on dose reduction and image quality using Monte Carlo simulations. This study particularly looks at t...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Sarah E. McKenney, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose:
While wide coverage (160 mm) CT scanners can image whole organs (e.g. heart, brain, kidneys, etc.) in one axial scan, the peripheral regions of the field of view (along z) suffer from cons...
Authors: Peymon Ghazi
Affiliation: MALCOVA Inc.
Abstract Preview: Purpose: To develop a near scatter‐free breast CT imaging system that expands coverage of the posterior breast anatomy and enhances contrast resolution for solid masses and microcalcifications, while ...
Authors: Jeff Boob, Jaydev K. Dave, Tim Minch, Bhavyata Tanna
Affiliation: Dr. Ronald E. McNair Academic High School, Mayo Clinic, CurveBeam AI
Abstract Preview: Purpose: To estimate effective doses associated with different imaging protocols for hip imaging with a cone beam CT (CBCT) scanner specifically designed for weight-bearing acquisitions.
Methods: A...
Authors: Salahuddin Ahmad, Imad M. Ali, Zaid Alkalani, Nesreen Alsbou
Affiliation: University of Oklahoma, University of Central Oklahoma, University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: To design and evaluate a 3D-detector for proton CT-imaging and radiography, utilizing volumetric plastic scintillator detector exposed to high-energy therapeutic beams from proton therapy sys...
Authors: Jadon O Buller, Yankun Lang, Liangzhong Xiang, Andrea Paulina Yanez
Affiliation: University of Maryland School of Medicine, University of California, Irvine
Abstract Preview: Purpose: With the widespread adoption of electroporation, there is growing interest in deep-tissue electric field monitoring. Electroporation therapy ablates target regions by generating electric fiel...
Authors: Yong Chen, Gilberto Gonzalez, Omprakash Gottam, Liangzhong Xiang
Affiliation: University of California, Irvine, Koneru Lakshmaiah Education Foundation, University of Texas at San Antonio., University of Oklahoma Health Science Center
Abstract Preview: Purpose: Clinics currently lack techniques for real-time, in vivo monitoring of radiation therapy (RT), which is desirable for precise treatment. Radiation-induced acoustic computed tomography (RACT) ...
Authors: Bryan Bednarz, Laura Bennett, Abby E. Besemer, Tyler J Bradshaw, Steve Y Cho, John M. Floberg, Joseph Grudzinski, Elissa Khoudary, Michael J. Lawless
Affiliation: Department of Radiology, University of Wisconsin, University of Wisconsin-Madison Department of Medical Physics, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Voximetry, Inc, University of Pennsylvania, Department of Radiology, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: To assess the impact of using a standardized immobilization setup for multi-time-point SPECT/CT imaging on radiopharmaceutical therapy (RPT) dosimetry image registration.
Methods: Ten ...
Authors: Petr Bruza, Alexander Geiersbach, David J. Gladstone, Lesley A Jarvis, Allison Matous
Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health
Abstract Preview: Purpose: During external beam radiation therapy, couch kicks are often necessary to achieve effective treatments, yet they make interpreting Cherenkov images much more challenging. We present a surfac...
Authors: Petr Bruza, Rafael Carballeira, Megan Clark, David J. Gladstone, Austin Sloop, Roman Vasyltsiv, Kevin Jacob Willy
Affiliation: Dartmouth College, Thayer School of Engineering, Dartmouth College
Abstract Preview: Purpose: Develop an optical dosimetry system to accomplish standard of care on-patient dosimetry and pretreatment quality assurance for ultra-high dose rate (UHDR) electron therapy ahead of human tria...
Authors: Rebecca Lamoureux, Zahra (Zara) Razi, Zachary Whipps
Affiliation: University of New Mexico Hospital
Abstract Preview: Purpose: Patient mispositioning in CT imaging contributes to inconsistent radiation dose delivery and suboptimal image quality, impacting patient safety and diagnostic outcomes. This study evaluates a...
Authors: Julia Brosch-Lenz, Munir Ghesani, Francesc Massanes, Michael Morris, Babak Saboury, Eliot Siegel, Alexander Hans Vija
Affiliation: Institute of Nuclear Medicine, Siemens Medical Solutions USA Inc., Molecular Imaging
Abstract Preview: Purpose: Quantitative imaging of the radiopharmaceutical distribution is crucial for treatment evaluation and dosimetry. However, as patient numbers for Lutetium-177-(177Lu)-labelled therapies continu...
Authors: Michael Baine, Yang Lei, Yu Lei, Ruirui Liu, Tian Liu, Jing Wang
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center
Abstract Preview: Purpose: Accurate 3D deformable registration of MRI and ultrasound (US) is essential for real-time image guidance during high-dose-rate (HDR) prostate brachytherapy. However, MRI-US registration of th...
Authors: Petr Bruza, Megan Clark, David J. Gladstone, Lesley A Jarvis, Allison Matous
Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health
Abstract Preview: Purpose: In vivo dosimetry (IVD) is underutilized, in part, because measured point doses cannot be accurately localized to the patient or treatment planning system (TPS), complicating the clinical and...