Authors: Lorenzo Arsini, Andrea Ciardiello, Fabio Massimo D'Amore, Stefano Giagu, Federico Giove, Carlo Mancini-Terracciano, Cecilia Voena
Affiliation: Istituto Superiore di Sanità, Sapienza University of Rome, Università Sapienza Roma, Magnetic Resonance for Brain Investigation Laboratory, Museo Storico della Fisica e Centro di Studi e Ricerche Enrico Fermi
Abstract Preview: Purpose: To leverage newly developed heteronuclear magnetic resonance imaging (MRI) techniques, particularly sodium (23Na) imaging, for identifying potential biomarkers of Alzheimer's disease—such as ...
Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Allison Dalton, John B Fiveash, Joel A. Pogue, Richard A. Popple, Farnaz Rahim Li
Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: External-beam Accelerated Partial Breast Irradiation (APBI) using stereotactic-body radiotherapy (SBRT) is increasingly adopted as an alternative to whole-breast radiation, offering targeted ...
Authors: Charmainne Cruje, Maria Dumol, Nawroz Fatima, Marisa Finlay, Kalaina Johnson, Raman Mohla, Jasleen Uppal
Affiliation: Trillium Health Partners, Carlo Fidani Regional Cancer Centre
Abstract Preview: Purpose: To evaluate the robustness of a breast SBRT protocol in achieving target coverage by utilizing online- and retrospectively-matched CBCT-to-CT images.
Methods: The first pilot patient was s...
Authors: Ruiyan Du, Mingzhu Li, Ying Li, Wei Liu, Shihuan Qin, Yiming Ren, Biao Tu, Hui Xu, Lian Zhang, Xiao Zhang, Zengren Zhao
Affiliation: Department of General Surgery, Hebei Key Laboratory of Colorectal Cancer Precision Diagnosis and Treatment, The First Hospital of Hebei Medical University, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Mayo Clinic, Department of Oncology, The First Hospital of Hebei Medical University
Abstract Preview: Purpose: Fiducial tracking is widely used in CyberKnife to dynamically guide the gantry for moving target like liver cancer stereotactic body radiation therapy (SBRT). This study developed a robust fr...
Authors: Silambarasan Anbumani, Nicolette O'Connell, Eenas A. Omari, Amanda Pan, Eric S. Paulson, Lindsay Puckett, Monica E. Shukla, Dan Thill, Jiaofeng Xu
Affiliation: Elekta Inc, Elekta Limited, Linac House, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Accurate electron density information from on-board imaging is essential for direct dose calculations in adaptive radiotherapy (ART). This study evaluates a deep learning model for thoracic s...
Authors: Quan Chen, Xue Feng, Chunhui Han, Gaofeng Huang, Trevor Ketcherside, Yi Lao, Yun Rose Li, An Liu, Bo Liu, Kun Qing, William T. Watkins
Affiliation: Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, City of Hope National Medical Center, Mayo Clinic Arizona, Carina Medical LLC
Abstract Preview: Purpose: New treatment platforms such as Ethos (Varian Medical Systems) allow the introduction of multi-modal imaging into adaptive radiotherapy workflow to facilitate an up-to-date view of patients’ ...
Authors: Ramesh Boggula, Nikhil Jordan Shad
Affiliation: Wayne State University
Abstract Preview: Purpose: To evaluate the effectiveness of OpenAI in reviewing large volumes of radiation delivery reports from Mobius3D/FX. The goal was to assess whether automating this process could identify potent...
Authors: Maria Jose Almada, Bruno Forti, Patricia Murina, Carlos Daniel Venencia
Affiliation: Instituto Zunino - Fundacion Marie Curie, Dra.
Abstract Preview: Purpose: The use of VMAT for the breast requires duplication of the patient's CT, several planning structures, and patient-specific dose-volume constraints depending on the patient's anatomy, fraction...
Authors: Eduardo Florian, Hiram Gay, Geoffrey D. Hugo, Otto Hurtarte, Milton Ixquiac, Erick Orlando Montenegro, Franky Eduardo Reyes, Francisco Javier Reynoso, Edgar Aparicio Ruiz, Baozhou Sun, Jacaranda Van Rheenen, Kevin Vega, Angel Velarde, Vicky de Falla
Affiliation: WashU Medicine, Liga Nacional Contra el Cancer, Liga Nacional Contra el Cancer/INCAN, Liga Nacional Contra el Cancer / INCAN, Liga Nacional Contra el Cancer and Universidad de San Carlos de Guatemala, Washington Univ. in St. Louis, Liga Nacional Contra el Cáncer / INCAN, Washington University in St. Louis, Varian, Baylor College of Medicine
Abstract Preview: Purpose:
IMRT has become the standard of care in high-income countries (HICs) due to reduced toxicity and improved treatment outcomes.
The purpose of this work is validating the KBP model shared...
Authors: Rodrigo Delgadillo, Nesrin Dogan, Benjamin J. Rich, Stuart E Samuels, Levent Sensoy
Affiliation: University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Daily Cone beam CT (CBCT) images may be useful in detecting early morphological changes during head and neck cancer radiotherapy. The aim of this study was to evaluate the performance of CBCT...
Authors: Mahmoud H Abdelgawad, Shahabeddin mostafanazhad Aslmarand, Lili Chen, Xiaoming Chen, Ahmed A. Eldib, Teh Lin, Chang Ming Charlie Ma, Robert A. Price
Affiliation: Physics department, Faculty of science, Al-Azhar University, Fox Chase Cancer Center
Abstract Preview: Purpose: Many modern radiotherapy clinics are moving to online adaptive radiotherapy. A recent upgrade of the CBCT-based adaptive radiotherapy system introduced ultra-high-speed image acquisition. Thi...
Authors: Girish Bal, Thomas I. Banks, Bin Cai, Yesenia Gonzalez, Zohaib Iqbal, Paul M. Medin, Rameshwar Prasad, Chenyang Shen, Robert Timmerman, Yuanyuan Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: Each year more than one million pacemakers and 200k cardioverter-defibrillators are implanted in patients worldwide. The presence of a CIED introduces challenges to the delivery of radiation ...
Authors: Kai-Cheng Chuang, Oana I. Craciunescu, Christopher Kelsey, Joseph Kowalski, Nicole Larrier, Xinyi Li, Sheridan G. Meltsner, Anna E. Rodrigues, Yang Sheng, Qiuwen Wu
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose: To clinically implement a Volumetric Modulated Arc Therapy (VMAT) procedure for Total Body Irradiation (TBI) with off-the-shelf tools.
Methods: Patient is treated on linac couch with a hyb...
Authors: Shupeng Chen, Xiaoda Cong, Raymond Dalfsen, Rohan Deraniyagala, Xuanfeng Ding, James E. Dolan, Xiaoqiang Li, Jian Liang, Peilin Liu, An Qin, Martin Soukup, Craig Stevens, Xiangkun Xu, Weili Zheng
Affiliation: Corewell Health William Beaumont University Hospital, Corewellhealth William Beaumont University Hospital, William Beaumont University Hospital, Elekta, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Corewellhealth William Beaumont Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital
Abstract Preview: Purpose: To facilitate clinical use of the proton feature of Monaco treatment planning system(TPS), we commissioned and validated it on a compact proton therapy system.
Methods: Pencil Beam Scannin...
Authors: Sorour Hosseini, YuHuei Jessica Huang, Jeremy Kunz, Nicholas Pierre Nelson, Ryan G. Price, Prema Rassiah, Hui Zhao
Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah
Abstract Preview: Purpose: To investigate the feasibility and clinical implications of creating customized workflows in a new SGRT system: LUNA 3D (LAP, Florida).
Methods: Three clinical SGRT workflows were designed...
Authors: Yong Chen, Christina Henson, Yuchen Qiu, Marti Roper
Affiliation: University of Oklahoma HSC, University of Oklahoma Health Sciences Center, University of Oklahoma, University of Oklahoma Health Science Center
Abstract Preview: Purpose: Traditionally, Head and Neck cancer patients have one or two treatment replans through their treatment course, which fails to account for anatomical changes in position, weight loss, or tumor...
Authors: Abid Khan, Chad Klochko, Michael J Kovalchick, Hyeok Jun Lee, Hani Nasr, Krishnan Shyamkumar, Kundan S Thind
Affiliation: Henry Ford Radiology, Wayne State University, Henry Ford Health, HFHS
Abstract Preview: Purpose: Automated vascular segmentation in interventional angiography is challenged by contrast kinetics, vessel variations, and 2D projections, limiting the effectiveness of single-model approaches....
Authors: Yaowen Cao, Yunwen Huang, Yidong Yang, Xiaogang Yuan, Ning Zhao, Cheng Zheng
Affiliation: Department of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China
Abstract Preview: Purpose: MRI has better soft tissue contrast than cone beam CT which is commonly used in image guided radiotherapy. This study aims to develop a low-field MRI system for precision small animal radiati...
Authors: Thomas R. Bortfeld, Prof. Elisabetta De Bernardi, Tianxue Du, Beatrice Foglia, Chiara Gianoli, Takamitsu Masuda, Katia Parodi, Marco Pinto, Boon-Keng Kevin Teo, Yunhe Xie
Affiliation: Department Of Radiation Oncology, Massachusetts General Hospital (MGH), School of Medicine and Surgery, University of Milano-Bicocca, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, National Institutes for Quantum Science and Technology (QST), University of Pennsylvania, Department of Experimental Physics - Medical Physics, Ludwig-Maximilians-Universität (LMU) München
Abstract Preview: Purpose: The full potential offered by protons in clinical practice is limited by range uncertainties. One possibility for monitoring is through secondary prompt gammas (PG). PG emission along the pen...
Authors: Yi Li
Affiliation: Department of Radiation Oncology, the First Affiliated Hospital of Xi'an Jiaotong University
Abstract Preview: Purpose: Advances in radiotherapy technology are crucial for improving cervical cancer (CC) treatment. This study explores a novel X-ray and γ-ray dual-modality radiation (TaiChiB) system, comparing i...
Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...
Authors: Minbin Chen, Gang Liu, Manju Liu, Weiwei Sang, Pulin Sun, Mingyuan Ye, Fang-Fang Yin, Lihua Zhang, Haiming Zhu
Affiliation: Jiahui International Hospital, Radiation Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: This study aims to conduct a dosimetric comparison between lattice radiotherapy (LRT) and 3D grid treatment planning techniques, focusing on their differences in delivering three-dimensional ...
Authors: Amar Kishan, Jun Lian, Yunkui Pang, Jonathan Pham, X. Sharon Qi, Michael Steinberg, Luca F Valle, Pew-Thian Yap
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of North Carolina at Chapel Hill
Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) is a highly effective treatment for prostate cancer, yet predicting genitourinary (GU) toxicity has primarily relied on planned dosimetry. This study inv...
Authors: Alexei V. Chvetsov, Pavitra Ramesh, Alexei V. Trofimov
Affiliation: Massachusetts General Hospital, University of Washington
Abstract Preview: Purpose: To investigate the effect of dose and depth dependence of relative biological effectiveness (RBE) on hypofractionated proton therapy for ocular melanoma using equivalent uniform RBE-weighted ...
Authors: Rita Buono, Elisabetta Cagni, Roberta Castriconi, Surendra Bahadur Chand, Marco Esposito, Claudio Fiorino, Valeria Landoni, Aldo Mazzilli, Eugenia Moretti, Lorenzo Placidi, Giulia Rambaldi Guidasci, Alessia Tudda
Affiliation: IRCCS San Raffaele Scientific Institute, Department of Advanced Technology, IRCCS Regina Elena National Cancer Institute, ASU FC Medical Physics, University Hospital of Parma AOUP, ICTP, B.P. Koirala Memorial Cancer Hospital, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Fatebenefratelli Isola Tiberina – Gemelli Isola
Abstract Preview: Purpose: To explore the feasibility and educational impact of transferring knowledge-based planning (KBP) models—developed using Italian breast radiotherapy data—to a Nepalese hospital, thereby demons...
Authors: Muhammad Ramish Ashraf, Girish Bal, Daniel Pham, Murat Surucu
Affiliation: RefleXion Medical, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University
Abstract Preview: Purpose: To determine minimum target size and FDG contrast thresholds for reliable Biology-guided Radiation Therapy (BgRT) delivery using a systematic phantom study.
Methods: A custom 3D-printed ph...
Authors: Damien C. Mathew, Brandon Hai Nguyen, Satwik Pani, Yoichi Watanabe
Affiliation: Minnespolis Radiation Oncology, Department of Radiation Oncology, University of Minnesota Medical School, Washington University
Abstract Preview: Purpose: To formulate a computational algorithm to quantify the tumor movement from the motion data of landmarks on the brain surface. To estimate the magnitude of tumor movement when the head makes a...
Authors: Shahabeddin mostafanazhad Aslmarand, Lili Chen, Dusica Cvetkovic, Troy A. Dos Santos, Chang Ming Charlie Ma, Dae-Myoung Yang
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose:
Pulsed low-dose-rate radiotherapy (PLDR) has been proposed to reduce normal tissue toxicity while maintaining tumor control comparable to conventional radiotherapy (CRT). This study assess...
Authors: Sunil Mani, Ilakiya Raghavendiran, Vasanthan Sakthivel, Skanda Kabilan Swamy
Affiliation: Edmond Santa Fe High School, Edmnd Deer Creek High, Cancer Specialists of North Florida, Advanced Medical Physics
Abstract Preview: Purpose: Purpose/Objective(s): To evaluate and validate the dose calculation and delivery accuracy for patients planned using diagnostic CT
Methods: A total of forty-two patients with palliative sp...
Authors: Shifeng Chen, Mariana Guerrero, Michael J. MacFarlane, Huijun Xu, Baoshe Zhang, Jinghao Zhou
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Capital Region Medical Center, University of Maryland Shore Regional Cancer Center
Abstract Preview: Purpose: The clinical value of surface-guided radiotherapy (SGRT) in prone breast cancer setups is much less established than in supine setups. This study explores SGRT's potential for prone breast pa...
Authors: Olubunmi Odunola Aregbe, Clara Ferreira, Margaret Reynolds, David A. Sterling, Jianling Yuan
Affiliation: University of Minnesota, University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: To analyze volume changes in the high-risk clinical target volume (HR-CTV) during high-dose rate (HDR) brachytherapy for cervical cancer patients. The study aims to evaluate the trend and cor...
Authors: Girish Bal, Thomas I. Banks, Bin Cai, Neil Desai, Aurelie Garant, Orhan Oz, Elizeva Phillips, Rameshwar Prasad, Chenyang Shen, Robert Timmerman
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: This study reports findings from the first-in-human imaging-only trial evaluating the feasibility of using the novel PET tracer 68Ga-PSMA-11 (Illuccix) to guide external beam radiotherapy on ...
Authors: Makunda Aryal, Qiongge Li, Sook Kien Ng, Christopher F. Njeh, Edwin Quashie, Senthamizhchelvan Srinivasan, Yun Wang
Affiliation: Indiana University Medical School, Memorial Health Care System, Indiana University, Inova Hospital, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: Linear-Quadratic-Linear (LQL) model is a modification of the traditional Linear-Quadratic model used in radiobiology to describe cell survival in response to radiation. The LQL model extends ...
Authors: Wesley E. Bolch, Chansoo Choi, Chan Hyeong Kim, Suhyeon Kim, Bangho Shin, Yeon Soo Yeom
Affiliation: Hanyang University, University of Florida, 2) Department of Radiation Convergence Engineering, Yonsei University
Abstract Preview: Purpose: Task Group 103 of International Commission on Radiological Protection (ICRP) recently released new-generation adult and pediatric mesh-type reference computational phantoms (MRCPs) via ICRP P...
Authors: Minbin Chen, Gang Liu, Manju Liu, Weiwei Sang, Pulin Sun, Mingyuan Ye, Fang-Fang Yin, Lihua Zhang, Haiming Zhu
Affiliation: Jiahui International Hospital, Radiation Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: This study aims to evaluate the effects of varying the number of arcs on treatment plans created using Volumetric Modulated Arc Therapy (VMAT) for Lattice radiotherapy (LRT).
Methods: Thre...
Authors: Marissa Brown, Geoffrey D. Clarke, Luke Norton
Affiliation: University of Texas Health Science Center at San Antonio
Abstract Preview: Purpose: To evaluate how different learning strategies affect convolutional neural network (CNN) estimates of the liver's intravoxel incoherent motion (IVIM) parameters.
Methods: A 3-stage U-Net wa...
Authors: Seungryong Cho, Donghyeok Choi, Joonil Hwang, Byung-Hee Kang, Jin Sung Kim, Eungman Lee, Younghee Park
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, KAIST, Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Ewha Womans University of Medicine
Abstract Preview: Purpose: Radiation therapy (RT) is critical for cancer treatment, but changes in tumor size and shape during therapy challenge precise dose delivery. Adaptive radiation therapy (ART) addresses these v...
Authors: Lukas M. Carter, Jazmin Schwartz
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Accurate lung shunt fraction (LSF) estimation is essential for the safety and efficacy of 90Y-radioembolization therapy. This study compares planar gamma camera imaging and tomographic SPECT-...
Authors: Olubunmi Odunola Aregbe, Clara Ferreira, Margaret Reynolds, David A. Sterling
Affiliation: University of Minnesota, University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: Current best practices recommend daily imaging and planning for Tandem and Ring (T&R) HDR patient plans. Accurate target delineation is a critical, yet time consuming step in this process. Th...
Authors: John T Barrett, Chulhaeng Huh, Farshad Mostafaei, Michelle Rocque, Austin Sanders
Affiliation: Department of Radiation Oncology, Medical College of Georgia, Augusta University, Department of Radiation Oncology, Augusta University, Georgia Radiation Therapy Center, Wellstar-MCG Health
Abstract Preview: Purpose: This study involved the use of Accuray’s TPS (Precision) and RayStation TPS for planning TBI treatments. TBI was delivered using Accuray’s Radixact machine, and dose calculation algorithm, do...
Authors: Hassan Bagher-Ebadian, Anthony J. Doemer, Ryan Hall, Joshua P. Kim, Bing Luo, Benjamin Movsas, Humza Nusrat, Kundan S Thind
Affiliation: Department of Physics, Toronto Metropolitan University, Henry Ford Health
Abstract Preview: Purpose: This study investigates the development and feasibility of local LLM-based agents to automate radiotherapy treatment planning, aiming to improve planning efficiency and consistency, while pre...
Authors: Won Chang, Vadim L. Stakhursky, Yevgeniy Vinogradskiy
Affiliation: Jefferson Einstein, Alliance Cancer Specialists, Thomas Jefferson University
Abstract Preview: Purpose: 4DCBCT is a powerful tool for localization of moving targets when treating lung tumors with hypofractionated regimens (SBRT). However, for patients with implanted cardiac devices (ICD) in clo...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang
Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose: Using mixed fractionation schemes is a common technique in treating CNS lesions. This article describes an innovative plan-and-split approach for more efficient planning on the ZAP-X and thus...
Authors: Mingyang Han, Jia Jing, Chongming Li, Hui Lin, Zhenyu Xiong
Affiliation: School of Physics, Hefei University of Technology, Rutgers Cancer Institute of New Jersey
Abstract Preview: Purpose: To enrich the teaching case library of Computational Physics course, one of the basic courses in undergraduates majoring in physics. It is an excellent application case of Medical Physics for...
Authors: Shahed Badiyan, Girish Bal, Thomas I. Banks, Bin Cai, Tu Dan, Aurelie Garant, Andrew R. Godley, Steve Jiang, Orhan Oz, Arnold Pompos, Rameshwar Prasad, Chenyang Shen, David Sher, Robert Timmerman, Kenneth Westover
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: Biology-guided radiotherapy (BgRT) is a novel FDA-cleared technology for treating lung and bone tumors based on 18F-FDG PET uptake. This study summarizes the first-year experience treating 29...
Authors: Zhongjie Lu
Affiliation: Department of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine
Abstract Preview: Purpose: Patients with locally-advanced head and neck squamous cell carcinomas(HNSCCs), particularly those related to human papillomavirus(HPV), often achieve good locoregional control(LRC), yet they ...
Authors: Jian Chen, Qiufen Guo, Aihua Li, Jing Liu, Junjie MA, Qian WU, Haonan Xiao, Peng Xie, Xiaohui Yan, Yong Yin, Zhe Zhang
Affiliation: Department of Radiation Oncology, Peking University Shenzhen Hospital, Department of Radiation Oncology and Physics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Obstetrics and Gynaecology, Liao Cheng People’s Hospital
Abstract Preview: Purpose: Online Adaptive radiation therapy (ART) has been an effective technique to manage patient’s inter-fractional anatomical changes and therefore reduces planning target volume (PTV). However, on...
Authors: Katja M. Langen, Mark McDonald, Bill Stokes, Yinan Wang, Suk Whan (Paul) Yoon
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Effective dose management in high-risk re-irradiation (ReRT) patients entails early, detailed special physics consultation (SPC) to mitigate risks from cumulative radiation dose. SPCs have tr...
Authors: Hua-Chieh Shao, You Zhang, Ruizhi Zuo
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Cone-beam CT (CBCT) provides on-board patient anatomy for image guidance and treatment adaptation in radiotherapy. However, to compensate for respiration-induced anatomical motion, motion-res...
Authors: Petr Bruza, Alexander Geiersbach, David J. Gladstone
Affiliation: Thayer School of Engineering, Dartmouth College
Abstract Preview: Purpose: Cherenkov images are two-dimensional projections of the surface light emissions, and lack spatial information about the radiotherapy beam delivery. We implement the first fusion of Cherenkov ...
Authors: Ruiyan Du, He Huang, Mingzhu Li, Ying Li, Hongyu Lin, Wei Liu, Shihuan Qin, Yiming Ren, Hui Xu, Lian Zhang, Xiao Zhang, Zunhao Zhang
Affiliation: Department of Radiation Oncology, Mayo Clinic, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Department of Oncology, The First Hospital of Hebei Medical University
Abstract Preview: Purpose: Monte Carlo (MC) dose calculation is the gold standard in clinical CyberKnife radiation therapy (RT), considering its steep dose gradients and high-freedom non-coplanar beam angles, but extre...
Authors: Jae Won Jung, Daniel Lee
Affiliation: Thomas S. Wootton High School, East Carolina University Brody School of Medicine
Abstract Preview: Purpose: Monkeys have played a key role in enhancing our understanding of the behavior of radioactive materials within living organisms in the field of nuclear medicine. However, detailed dosimetric d...
Authors: Kim Creach, Kim Howard, Julius G. Ojwang, Richard A. Shaw, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: To present a standardized MRI-CT hybrid workflow for High-Dose-Rate (HDR) Image-Guided Adaptive Brachytherapy (IGBT) in cervical cancer, aligned with AAPM TG-303, as a model to assist with im...
Authors: Brian M. Anderson, Simon A. Brundage, Xuguang Scott Chen, Shiva K. Das, Felice Dong, Spencer Lynch, Panayiotis Mavroidis, Ryan Morse Morse, Heidi Urquidi
Affiliation: University of North Carolina Chapel Hill, University of North Carolina at Chapel Hill, University of North Carolina
Abstract Preview: Purpose: This study aims at correlating different dosimetric indices of nodal GTV with the regional recurrencies observed after head and neck radiotherapy. Also, to perform a tumor control probability...
Authors: Avery Antes, Bulent Aydogan, Rama Chicfeh, Erik Pearson, Neslihan Sarigul
Affiliation: The University Of Chicago, The University of Chicago
Abstract Preview: Purpose: This study evaluates the performance of the Ethos Treatment Planning System (TPS) in managing oligometastatic cancer patients previously treated using multiple isocenter plans.
Methods: Th...
Authors: Anthony R Bardwell, Dong Won Kim, Faith S Kim, Isaac Y Kim, Juying Zhang
Affiliation: Kaiser Permanente
Abstract Preview: Purpose: When a patient develops a significant skin reaction at some point during postmastectomy radiotherapy, a clinical decision is often made to discontinue the planned daily use of bolus. The aim ...
Authors: Anthony J. Doemer, Bing Luo, Benjamin Movsas, Humza Nusrat, Farzan Siddiqui, Chadd Smith, Kundan S Thind, Kyle Verdecchia
Affiliation: Department of Physics, Toronto Metropolitan University, Henry Ford Health
Abstract Preview: Purpose: Large-vision models (LVMs) are rapidly emerging, yet their application in radiation oncology remains largely unexplored. This study investigates the potential of LVMs for offline adaptive rad...
Authors: Jenny Dankelman, Ben J. M. Heijmen, Inger-Karine K. Kolkman-Deurloo, Remi A. Nout, Linda Rossi, Robin Straathof, Linda Wauben, Henrike Westerveld, Nick J. van De Berg, Sharline M. van Vliet - Perez
Affiliation: Department of BioMechanical Engineering, Delft University of Technology, Department of Gynecological Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam
Abstract Preview: Purpose:
To quantify the dosimetric advantages of the 3D-printed patient-tailored ARCHITECT applicator with optimized needle channel configurations compared to clinically used intracavitary/interst...
Authors: Joseph A. Miccio, Nicholas J. Potter, Zain Siddiqui
Affiliation: Penn State Health Milton S. Hershey Medical Center
Abstract Preview: Purpose: Fiducial markers are the gold standard for prostate alignment during CT-based image-guided radiotherapy (IGRT). Radiopaque hydrogel rectal spacers reduce rectal toxicity by displacing the rec...
Authors: Matthew C Abramowitz, Alan Dal Pra, Rodrigo Delgadillo, Nesrin Dogan, John C. Ford, Kyle R. Padgett, Levent Sensoy, Benjamin Spieler, Matthew T. Studenski, Jace Allen Walker
Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center, University of Miami School of Medicine
Abstract Preview: Purpose:
Toxicities that affect a patient’s quality-of-life due to prostate cancer (pCa) radiation therapy (RT) are receiving more attention as RT has become increasingly successful in treating pCA...
Authors: Casey E. Bojechko, Tricia Chinnery, Grace Gwe-Ya Kim, Xenia Ray
Affiliation: University of California San Diego
Abstract Preview: Purpose: To evaluate the use of a calibration curve generated from the CT simulator for direct dose calculation on cone beam computed tomography (CBCT) images taken with the on-board imaging system. T...
Authors: Jean-Pierre Bissonnette, Catherine Coolens, Laura Dawson, Ryan A Kuhn, Michael Maddalena, Teo Stanescu
Affiliation: Princess Margaret Hospital, The Princess Margaret Cancer Centre - UHN, University of Toronto, Princess Margaret Cancer Centre
Abstract Preview: Purpose: To investigate the generation and reproducibility of 3D hypoxia maps in liver hepatocellular carcinoma (HCC) patients using data derived from an Intravoxel Incoherent Motion (IVIM) MR sequenc...
Authors: Go Akamatsu, Hiroaki Ikawa, Yuma Iwao, Han Gyu Kang, Masashi Koto, Hideyuki Mizuno, Akram Mohammadi, Makoto Shinoto, Minoru Tajiri, Hideaki Tashima, Chie Toramatsu, Taiga Yamaya
Affiliation: National Institutes for Quantum Science and Technology
Abstract Preview: Purpose: In-beam positron emission tomography (PET), in which positron emitters produced through fragmentation reactions are visualized, is a practical method for range verification in particle therap...
Authors: Michael B. Altman, Sharbacha Edward, Jose L. Garcia Ramirez, Anamaria Guta, Elizabeth Gaines Jeong, Justin K. Mikell, Phillip D. H. Wall, Jacqueline Esthappan Zoberi
Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, WashU Medicine
Abstract Preview: Purpose: Modern HDR remote afterloaders (RAL) are equipped with enhanced safety features for accurate source positioning. However, little guidance is provided on the use of these features. We have cli...