Authors: Jeremy S. Bredfeldt, Cindy I. Hancox, Arianna Liles, Alex Marques, Usha Tedrow
Affiliation: Department of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School
Abstract Preview: Purpose: Ventricular tachycardia (VT) can be treated using cardiac radioablation. 4DCT simulation is commonly used, however, contrast injection timing is challenging. This study aimed to develop a pro...
Authors: Aaron Conard, Victoria Croog, Marie Gurka, Lan Lin
Affiliation: Johns Hopkins University
Abstract Preview: Purpose:
This study evaluates the utility of the Active Breathing Coordinator (ABC) and Surface Guided Radiation Therapy (SGRT) techniques in implementing Deep Inspiration Breath Hold (DIBH) for le...
Authors: Hongyu An, Phillip Cuculich, H Michael Gach, Yao Hao, Trevor McKeown, Clifford Robinson, Yuhao Wang, Deshan Yang
Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, Duke University, Department of Radiation Oncology, Duke University, Washington University in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis
Abstract Preview: Purpose: This study investigated cardiac motion characteristics of ventricular tachycardia patients to support patient-specific motion management for stereotactic arrhythmia radiotherapy (STAR) treatm...
Authors: Hui-Shan Jian, Yu-Ying Lin
Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou
Abstract Preview: Purpose: The image quality assurance of mammographic images is crucial for correct diagnosis. To develop and validate an explainable deep-learning classifier for phantom image quality assessment of di...
Authors: Juan-Francisco Calvo-Ortega, Andrew Cousins, Ashley Cullen, Andrew Dipulia, Peter B. Greer, Seng Boh Gary Lim, Shih-Chi Lin, D. Michael Lovelock, Conor McGarry, Victoria Robinson, Cameron Stanton, Baozhou Sun, Ching-Ling Teng, Gemma Warner, Benjamin J. Zwan
Affiliation: Northern Ireland Cancer Centre, Baylor College of Medicine, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Christchurch Hospital, Northwell, Central Coast Cancer Centre, Calvary Mater Hospital, Hospital Quironsalud Barcelona, Icahn School of Medicine at Mount Sinai, Chris O'Brien Lifehouse, University of Newcastle
Abstract Preview: Purpose: This multi-institution Electronic Silicon-based Remote Survey of Small-field Output (ESPRESSO) study aims to develop the remote audit process to evaluate the safety of single-isocenter multi-...
Authors: Rami M. Shorti, Gary R. Stinnett
Affiliation: Intermountain Health, Radiation Oncology, Intermountain Health, Advanced Visualization Engineering Department
Abstract Preview: Purpose: In this work we present the workflow, materials analysis, and lessons learned from leveraging advanced 3D printing Polyjet Technology to print conformal bolus for radiation therapy.
Method...
Authors: Gary Y. Ge, Azmul Siddique, Jie Zhang
Affiliation: Department of Radiology, University of Kentucky, University of Kentucky
Abstract Preview: Purpose: Virtual grid technology addresses scattered radiation without a physical grid, offering the potential to reduce patient radiation dose while maintaining image quality. However, this potential...
Authors: Cristel Baiu, Laura Castaneda Martinez, Ivan M. Rosado-Mendez
Affiliation: University of Wisconsin, Department of Medical Physics, University of Wisconsin-Madison, Departments of Medical Physics and Radiology, University of Wisconsin-Madison
Abstract Preview: Purpose: 2D matrix array transducers (2DMAT) are advancing volumetric ultrasound due to their ability to provide more isotropic 3D resolution, fast volumetric imaging, and highly customizable focusing...
Authors: Andrew Huang, Jonathan Huang, Andrew S Kennedy, Ellie Grace Kong, Ajay Zheng
Affiliation: New York Proton Center, Centennial Medical Center, Executive Medical Physics Associates, Sarah Cannon Cancer Institute, Belmont University
Abstract Preview: Purpose:
Lung stereotactic body radiotherapy (SBRT) is the standard of care for early-stage lung cancer. Respiratory phase gating can be applied to mitigate motion-induced effects. The purpose of t...
Authors: Amar K. Basavatia, Lee C. Goddard, Rachel Grimm, Wolfgang A. Tomé
Affiliation: Montefiore Medical Center
Abstract Preview: Purpose: To characterize the “MyOSL Chip” OSLD system for clinical use and compare the response of multiple readers to allow for utilization in a multi-clinic environment.
Methods: Dose calibration...
Authors: Milad BaradaranGhahfarokhi, Manuel A. Morales Paliza
Affiliation: Vanderbilt University Medical Center
Abstract Preview: Purpose: The purpose of this study was to commission Varian HDR surface applicators using a high-resolution diode array and film dosimetry. This work evaluates dosimetric characteristics of these appl...
Authors: Niko Ahjoniemi, Antti Kulmala, Katja Peltola
Affiliation: Clinical Research Institute HUS, Helsinki University Hospital
Abstract Preview: Purpose: To determine the backlash of a multileaf collimator (MLC) using four measurement methods: motor encoder (primary readout), linear potentiometer (secondary readout), amorphous silicon panel (p...
Authors: Sarah Aubert, Harald Keller, Jeff D. Winter
Affiliation: Princess Margaret Cancer Centre
Abstract Preview: Purpose: Support for treatment planning directly on CBCT imaging on C-arm linacs will enable adaptive radiation therapy (ART) capacity with increased treatment technique flexibility. The HyperSight im...
Authors: Yunfeng Cui, Will Giles, Xinyi Li, Ke Lu, Jennifer C. O'Daniel, Anna E. Rodrigues, Chunhao Wang, Lana Wang, Yibo Xie, Sua Yoo, Jingtong Zhao
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose:
To establish quantitative measurement of plan modulation for SRS/SBRT treated with Volumetric Modulated Arc Therapy (VMAT) on C-arm LINACs.
Methods:
A total of 461 plans were analyze...
Authors: Ziyad ABUBAKR ALHAREESHi, Ibtihaj Yussef Alhodire, Najla Sobhi Bin Shehima, Aram Mufteh A Genaw
Affiliation: Tripoli university hospital
Abstract Preview: Purpose:
This research investigates the recombination and polarity correcting factors for CC04, CC13, FC65P, FC65G, Razor, and PP05 ionization chambers to improve radiation dosimetry accuracy. Unde...
Authors: Emi Ai Eastman, Christina Lee, Xinhua Li, Alexander W. Scott, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose: Iterative reconstruction (IR) methods are valuable for reducing dose in modern CT; however, IR methods have the effect of reducing spatial resolution and hence the lesion edge sharpness. Furt...
Authors: Ryan Andosca, Igor Barjaktarevic, Peter Boyle, Jie Deng, Minji Victoria Kim, Michael Vincent Lauria, Daniel A. Low, Claudia R. Miller, Drew Moghanaki, Louise Naumann, Jack Neylon, Dylan P. O'Connell, Ricky R Savjani
Affiliation: Department of Pulmonology, University of California Los Angeles, University of California, Los Angeles, Department of Radiation Oncology, University of California, Los Angeles, UCLA, UCLA Radiation Oncology
Abstract Preview: Purpose: To develop a Hounsfield Unit ventilation-based correction method for use with model-based CT when used as a replacement for 4DCT.
Methods: The model-based CT we employ is termed 5DCT, whic...
Authors: Ehsan Abadi, Njood Alsaihati, Steven T. Bache, Mridul Bhattarai, Cindy Marie McCabe, Francesco Ria, Ehsan Samei
Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Duke University Health System, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: To compare and contrast alternative methods including reader (in hominum), phantom (in phantasma), in vivo, and in silico methods deployed to assess the performance of photon counting (PCCT) ...
Authors: Sang Hyun Cho, Amrit Kaphle, Sunil Krishnan, Neerajan Nepal
Affiliation: The University of Texas MD Anderson Cancer Center, The University of Texas Health Science Center
Abstract Preview: Purpose: To determine the basic dosimetry parameters and characteristics of a commercial cabinet x-ray unit for small animal irradiation as well as the specific dosimetry parameters for concurrent irr...
Authors: Jennifer L. Dolan, Chengyin Li, Parag Parikh, Doris N. Rusu, Kundan S Thind
Affiliation: Henry Ford Health, Cedars-Sinai Medical Center
Abstract Preview: Purpose: The time and resource demands of online Adaptive Radiation Therapy (ART) can limit its widespread clinical adoption and potentially impact patient throughput. To address this, we developed a ...
Authors: Ben Archibald-Heeren, Grace Gwe-Ya Kim, Kelly Kisling, Xenia Ray
Affiliation: UC San Diego, Icon Cancer Centres, University of California, San Diego, University of California San Diego
Abstract Preview: Purpose: To evaluate improvements in external beam plans for gynecological cancers from a novel planning solution: RapidArc Dynamic (RAD) (Varian Medical Systems, Palo Alto, CA) which optimizes VMAT w...
Authors: Milad BaradaranGhahfarokhi, Ashley Elizabeth Bonner, James R. Burns, Annie Cooney, George X. Ding, Kenneth L. Homann, Guozhen Luo
Affiliation: Corewell Health William Beaumont University Hospital, Vanderbilt University Medical Center
Abstract Preview: Purpose: The goal of this study was to evaluate the performance of a new plastic scintillating detector (PSD) system with 0.5×0.5 mm2 and 1.0×1.0 mm2 probes (referred to as Medscint0.5 and Medscint1.0...
Authors: Junghoon Lee, Todd R. McNutt, Harry Quon, Bohua Wan
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, Department of Computer Science, Johns Hopkins University
Abstract Preview: Purpose: Xerostomia is a common toxicity in head and neck cancer (HNC) radiotherapy (RT). A few deep learning (DL) models have been proposed to predict the chance of xerostomia 12 months after RT with...
Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Wagner Henrique Marques, Raphael Morata, Victor H.F Oliveira
Affiliation: University of São Paulo (USP), Institute of Physics
Abstract Preview: Purpose: This study investigates the feasibility of 3D printing materials in creating anthropomorphic kidney phantoms that accurately simulate the radiological properties of human tissues, for applica...
Authors: Xiaodong Wu, Xingchen Zhai, Weizhao Zhao
Affiliation: University of Miami
Abstract Preview: Purpose: The ZAP-X is a self-contained, self-shielded radiosurgery system utilizing a 3MV LINAC. Its self-shielded design, poses challenges for conventional beam quality assurance (QA) methods. This s...
Authors: Xinhua Li, Jie Zhang, Yifang (Jimmy) Zhou
Affiliation: University of Kentucky, Cedars-Sinai Medical Center
Abstract Preview: Purpose: Fat volume fraction (FVF) is an important biomarker for non-alcoholic fatty liver disease. CT can be a good modality for FVF assessment if the accuracy is adequate. We aimed to study the impa...
Authors: Muhammed AR Anjum, Andrew J. Fagan
Affiliation: Mayo Clinic
Abstract Preview: Purpose:
This study describes a novel post-processing method to boost image SNR for deuterium-MRI acquired using chemical shift imaging (CSI) at 7T. Deuterium MRI via exogenous administration of a ...
Authors: Amy Berrington de Gonzalez, Keith T Griffin, Jae Won Jung, Cari M Kitahara, Choonik Lee, Choonsik Lee, Aimee L McNamara, Matthew Mille, Harald Paganetti, Sergio Morato Rafet, Jan PO Schuemann, Jungwook Shin, Torunn I Yock
Affiliation: University of Michigan, East Carolina University, Massachusetts General Hospital, National Cancer Institute, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Massachusetts General Hospital and Harvard Medical School, Institute of Cancer Research
Abstract Preview: Purpose: Radiotherapy dose reconstruction enables retrospective epidemiological studies that connect late health effects to the organ-absorbed radiation doses received during treatment. Though clinica...
Authors: Omer Gal, Alonso N. Gutierrez, Matthew D. Hall, Rupesh Kotecha, Minesh P. Mehta, Andrew J. Wroe, Jen Yu
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose: Linear energy transfer (LET) is directly related to relative-biological-effectiveness dose in proton therapy. This study aims to investigate how the treatment field hinge angles affect LET of...
Authors: Rico Castillo, Katherine Gonzalez, Casey C. Heirman, Kyle J. Lafata, Casey Y. Lee, Xiang Li, Yvonne M Mowery, Yvonne M Mowery, Daniel Murphy, Allison Pittman, Ashlyn G. Rickard
Affiliation: Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh
Abstract Preview: Purpose: To evaluate the ability of a deep learning model to identify pathomic features in lymph nodes of preclinical head and neck squamous cell carcinoma (HNSCC) models as surrogates for predicting ...
Authors: Jonathan Dowell, Wei Luo, Shane McCarthy, Janelle A. Molloy, Markus Murphy
Affiliation: University of Kentucky, Department of Radiation Medicine, Iridesce Solutions, Inc.
Abstract Preview: Purpose: The novel machine quality assurance (QA) device nüFilm (Iridesce Solutions, Lexington KY) allows for an objective assessment of light and radiation fields independent of setup. Herein, the ab...
Authors: Stephanie Bennett, Ross I. Berbeco, Ning Jin, Sonal Josan, Justin Michael Sheetz, Atchar Sudhyadhom
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Massachusetts - Lowell, Siemens Healthineers, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Women's Hospital
Abstract Preview: Purpose: AGuIX, a Gadolinium-based theranostic radiosensitizing nanoparticle, is currently under clinical evaluation in Europe and the US. Using patients from the double-blinded NanoBrainMets trial, u...
Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu
Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center
Abstract Preview: Purpose: The purpose of this work is to describe the design and development of a newly developed upright-geometry dedicated breast CT system and to quantitatively and qualitatively evaluate its imagin...
Authors: Shifeng Chen, Erica Fisler, Arun Gopal, Mariana Guerrero, Jason Hendershot, Kai Huang, Eric Kusmaul, Adam Schrum, Megan Steinberg, Kai Wang
Affiliation: University of Maryland School of Medicine, Department Radiation Oncology, Kaufman Cancer Center, Upper Chesapeake Medical Center, University of Maryland Medical System Central Maryland Radiation Oncology, Department of Radiation Oncology, University of Maryland Medical Center, Baltimore Washington Medical Center Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose:
Our goal is to develop and clinically deploy an automated planning tool using multicriteria optimization (MCO) for VMAT in prostate only, whole pelvis radiotherapy treatments.
Methods:<...
Authors: Paul J. Black, Jordan B Lunsford, James D. Ververs, India Wood
Affiliation: Atrium Health Wake Forest Baptist, Wake Forest University School of Medicine, Wake Forest School of Medicine
Abstract Preview: Purpose:
To develop a 3D-printed modular CT simulator phantom that allows the assessment of all AAPM TG-66 recommended monthly quality assurance (QA) tests.
Methods:
A modular CT simulator mo...
Authors: Yankui Chang, Shijun Li, Xi Pei, Ripeng Wang, Xuanhe Wang, X. George Xu, Qing Zhang, Jingfang Zhao
Affiliation: University of Science and Technology of China, Shanghai proton and heavy ion center, School of Nuclear Science and Technology, University of Science and Technology of China, Anhui Wisdom Technology Co., Ltd.
Abstract Preview: Purpose:
This paper describes disruptive methods using both GPU-based MC simulation and deep-learning (DL)-based MC denoising algorithms, as well as clinical tests involving more than 560 patient p...
Authors: David L. Barbee, Jose R. Teruel Antolin, Jinyu Xue
Affiliation: NYU Langone Health
Abstract Preview: Purpose: This work introduces a method of regional dose evaluation of normal brain tissue using local target-specific evaluation and compares to global dose evaluation for linac-based single-isocenter...
Authors: Grant Gibbard, Chunhui Han, An Liu
Affiliation: RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the efficacy of a new approach to streamline treatment planning for biology-guided radiotherapy (BgRT) of fluorodeoxyglucose (FDG)-avid bony lesions on a BgRT machine with real-ti...
Authors: Jie Deng, Yunxiang Li, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Magnetic Resonance Imaging (MRI) has exceptional soft tissue contrast and an essential role in radiotherapy. The introduction of clinical MR-LINACs has enabled adaptive radiotherapy (ART) usi...
Authors: Klaus Bacher, Louise D'hondt, Jeff Rutten, Gwenny Verfaillie
Affiliation: Ghent University
Abstract Preview: Purpose: Manual organ segmentation is a very time-consuming but necessary process in personalized dosimetry. Automatic segmentation tools may alleviate this task. In this study the impact of automatic...
Authors: Caiden Atienza, Daniel E. Hyer, Samuel D. Rusu, Blake R. Smith, Joel J. St-Aubin
Affiliation: Iowa Health Care, University of Iowa
Abstract Preview: Purpose: Pinnacle3 TPS (Philips Radiation Oncology Systems, Fitchburg, WI, USA) support is set to end by December 31, 2026. This work presents a validated method to archive Pinnacle data, which may be...