Authors: Chin-Cheng Chen, Chia-Ho Hua, Christopher J. Kutyreff, Thomas E. Merchant
Affiliation: St. Jude Children's Research Hospital
Abstract Preview: Purpose: A dosimetric study was conducted to determine the optimal field parameters for a commercially available small-field applicator (SFA) used in spot-scanning proton stereotactic radiosurgery, pa...
Authors: Shari Damast, Svetlana Kuznetsova, Christopher J. Tien
Affiliation: Yale University School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: Current contour similarity evaluation approaches (Dice Similarity Coefficient, Mean Distance to Agreement) are limited to geometric agreement without assessment of ultimate dosimetric impact....
Authors: Wesley E. Bolch, Carlos G. Colon-Ortiz, Robert Joseph Dawson, Lazaro Fuentes Alfonso, Shreya P. Pathak, Julia D. Withrow
Affiliation: University of Florida
Abstract Preview: Purpose: To develop tetrahedral mesh-based tissue models within the breasts of the International Commission on Radiological Protection (ICRP) adult female mesh-type reference computational phantom (AF...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Samuel Richter, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study evaluates the necessity and potential benefits of online adaptive stereotactic body radiotherapy (SBRT) for prostate cancer using the ViewRay MR-Linac system. By leveraging real-ti...
Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Haley Park, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose:
Pancreatic cancer poses therapeutic challenges due to the proximity of critical organs, requiring precise radiotherapy. Magnetic resonance (MR)-guided linear accelerators provide daily ima...
Authors: Dan Giardina, John Karageorgiou, Chris Malone, Naganathan Mani, Allan Thomas
Affiliation: Washington University School of Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine
Abstract Preview: Purpose: Relative to planar imaging, MAA-SPECT/CT offers more reliable lung shunt fraction (LSF) and lung mean dose (LMD) estimates in 90Y radioembolization. But lung truncation in SPECT/CT can limit ...
Authors: Mark E Artz, Jiyeon Park, Lori Rice, Mohammad Saki, Sanjeev Shukla, Michael Vieceli
Affiliation: University of Florida Health Proton Therapy Institute, Department of Radiation Oncology, University of Florida College of Medicine, UF Health Proton Therapy Institute, Department of Urology, University of Florida College of Medicine
Abstract Preview: Purpose: To investigate how varying levels of DNA repair mutations affect the LET sensitivity of prostate cancer cells.
Methods: The prostate cancer cell lines Du145 (low DNA repair mutations), PC3...
Authors: Michalis Aristophanous, Steven Blum, Laura I. Cervino, Antonio L. Damato, Karen Episcopia, Chi Huang, Shih-Chi Lin, Michelle K. Savacool
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Varian Ethos (Varian Medical Systems, Palo Alto, CA) is a 6 MV flattening-filter-free (FFF) only machine, posing a challenge in creating homogeneous dose distributions when using manual 3D-CR...
Authors: Jonathan J. Chen, Alexei V. Chvetsov, Yulun He, Ramesh Rengan, Andrew Stacey, Kent Wallner
Affiliation: University of Washington and Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: To show that the RBE of low-energy photon sources used in COMS (Collaborative Ocular Melanoma Study) eye plaques compensates for protracted irradiation and attenuation of low-energy photons i...
Authors: Sorour Hosseini, YuHuei Jessica Huang, Jeremy Kunz, Nicholas Pierre Nelson, Ryan G. Price, Prema Rassiah, Hui Zhao
Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah
Abstract Preview: Purpose: To investigate the feasibility and clinical implications of creating customized workflows in a new SGRT system: LUNA 3D (LAP, Florida).
Methods: Three clinical SGRT workflows were designed...
Authors: Hyo-Min Cho, Cheolpyo Hong, Changwoo Lee, Sunyoung Lee
Affiliation: Daegu Catholic University, Korea Research Institute of Standards and Science (KRISS), Korea Research Institute of Standards and Science
Abstract Preview: Purpose: With the increasing prevalence of metabolic syndrome, the importance of diagnosing obesity and fatty liver diseases has grown significantly. As a result, there is a rising demand for non-inva...
Authors: Ahmad Amoush, Adam C. Riegel
Affiliation: Columbia University Irving Medical Center
Abstract Preview: Purpose: To investigate the dosimetric differences between the reference CT plan, the scheduled plan, and the adaptive plan for a bladder cancer patient treated with Varian Ethos system.
Methods: A...
Authors: Dennis A. Cheek, Wei Luo, Cameron Thayer-Freeman, Brien Timothy Washington
Affiliation: UT Southwestern Medical Center, University of Kentucky, Department of Radiation Medicine, University of Kentucky
Abstract Preview: Purpose: To investigate the effect of variation in the α/β of cervical cancer on clinical outcome for cervix cancer patients treated with radiation therapy.
Methods: A distribution of experimentall...
Authors: Li Tong, Chuyan Wang, Zhengkui Wang, Yingli Yang, Jie Zhang
Affiliation: Shanghai United imaging Healthcare Advanced Technology Research Institute, Shanghai United Imaging Healthcare Co., LTD, Department of Radiology, Ruijin Hospital, Institute for Medical Imaging Technology, Ruijin Hospital
Abstract Preview: Purpose:
Pelvic radiotherapy (RT)-induced bone marrow (BM) damage affects patient prognosis by causing hematologic toxicity. However, consensus on BM-sparing (BMS) RT is still lacking, owing to the...
Authors: Wesley E. Bolch, Chansoo Choi, Chan Hyeong Kim, Suhyeon Kim, Bangho Shin, Yeon Soo Yeom
Affiliation: Hanyang University, University of Florida, 2) Department of Radiation Convergence Engineering, Yonsei University
Abstract Preview: Purpose: Task Group 103 of International Commission on Radiological Protection (ICRP) recently released new-generation adult and pediatric mesh-type reference computational phantoms (MRCPs) via ICRP P...
Authors: Richard Dortch, Thammathida Ketsiri, Zhiqiang Li, Shiv P. Srivastava
Affiliation: Barrow Neurological Institute, Dignity Health Cancer Institute, St. Joseph's Hospital & Medical Center
Abstract Preview: Purpose: Imaging the spinal cord post-surgery is challenging due to metal surgical implants, which induce signal loss and geometric distortions. Together, this hinders the visualization of the spinal ...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, Dan Nguyen, Justin D. Visak, Hui Ju Wang, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Knowledge-based planning (KBP) plays a crucial role in improving treatment plans by leveraging previous clinical data to guide new cases. KBP is applied to the Ethos 2.0 Intelligent Optimizat...
Authors: Bin Cai, Andrew R. Godley, Brian A. Hrycushko, Heejung Kim, Mu-han Lin, David D.M. Parsons, Justin D. Visak, Da Wang, Tingliang Zhuang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: The standard radiation therapy workflow requires CT-simulation and planning, whether for initial treatments or re-planning due to significant anatomical changes. IPART instead uses one patien...
Authors: Hania A. Al-Hallaq, Duncan Henry Bohannon, Chih-Wei Chang, Anees H. Dhabaan, Vishal Dhere, H Scott McGinnis, Pretesh Patel, Sagar Patel, Keyur Shah, Xiaofeng Yang, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Two-fraction proton SABR is an attractive alternative to brachytherapy for localized prostate cancer. However, potential interfractional anatomical changes necessitate online adaptation, espe...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, David D.M. Parsons, Justin D. Visak, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Adaptive radiotherapy (ART) programs are resource-intensive due to their technical complexities, requiring highly skilled planners. Leveraging integrated automated treatment planning system (...
Authors: Tess Armstrong, Nema Bassiri, Alonso N. Gutierrez, Michael Kasper, Natalia Lutsik, Eric Mellon, Kathryn E. Mittauer, Siamak P. Nejad-Davarani, Shyam Pokharel, Suresh Rana, Hui Wang, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Miami Cancer Institute, Baptist Health South Florida, ViewRay, Inc., Miami Cancer Institute, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Department of Radiation Oncology, University of Miami
Abstract Preview: Purpose: Radiation treatments on the MR-linac (MRL) enable daily acquisition of anatomical and physiological images for adaptive treatment planning. The apparent diffusion coefficient (ADC) estimated ...
Authors: Seungtaek Choi, Laurence Edward Court, Eun Young Han, Yusung Kim, Hunter S. Mehrens, Tucker J. Netherton, Shiqin Su
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Automated treatment planning is gaining traction for its enhanced consistency and efficiency. A key challenge, however, lies in the inability of neural network dose predictions directly trans...
Authors: Wesley E. Bolch, Chansoo Choi, Robert Joseph Dawson, Michael Lassmann, Maikol Salas-Ramirez, Bangho Shin, Johannes Tran-Gia, Yitian Wang
Affiliation: Department of Nuclear Medicine, University Hospital Würzburg, University of Florida
Abstract Preview: Purpose: Conduct a parameterized library of mesh-type skeletal models across the lumbar vertebrae. In radiopharmaceutical dosimetry, the hematopoietic active bone marrow is typically a dose-limiting n...
Authors: Jian Chen, Qiufen Guo, Aihua Li, Jing Liu, Junjie MA, Qian WU, Haonan Xiao, Peng Xie, Xiaohui Yan, Yong Yin, Zhe Zhang
Affiliation: Department of Radiation Oncology, Peking University Shenzhen Hospital, Department of Radiation Oncology and Physics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Obstetrics and Gynaecology, Liao Cheng People’s Hospital
Abstract Preview: Purpose: Online Adaptive radiation therapy (ART) has been an effective technique to manage patient’s inter-fractional anatomical changes and therefore reduces planning target volume (PTV). However, on...
Authors: Hua-Chieh Shao, You Zhang, Ruizhi Zuo
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Cone-beam CT (CBCT) provides on-board patient anatomy for image guidance and treatment adaptation in radiotherapy. However, to compensate for respiration-induced anatomical motion, motion-res...
Authors: Lili Chen, Xiaoming Chen, Chang Ming Charlie Ma, Joshua Meyer
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Fast CBCT (HyperSight) acquisition technique together with a surface-guided breath-hold (SGBH) would allow a better image quality for accurate target/organ delineation. It facilitates breath-...
Authors: Danielle Renee Daiger, Nicholas N. Sperling
Affiliation: University of Toledo, University of Toledo Medical Center
Abstract Preview: Purpose:
To retrospectively evaluate the impact of planned delivery time on plan quality metrics for breath-hold VMAT SBRT thoracic cancer patients.
Methods:
Patients treated for SBRT thoraci...
Authors: Yukio Fujita, Satoshi Ishikura, Fumiki Ito, Yujiro Nakajima, Takumi Sakamoto, Naoki Tohyama, Ryohei Yamauchi
Affiliation: Komazawa University Graduate School, St. Luke's International Hospital
Abstract Preview: Purpose: The aperture shape controller (ASC) is an Eclipse feature that increases muti-leaf collimator (MLC) aperture size. This study aimed to evaluate the effects of ASC settings on the robustness o...
Authors: Jae Won Jung, Daniel Lee
Affiliation: Thomas S. Wootton High School, East Carolina University Brody School of Medicine
Abstract Preview: Purpose: Monkeys have played a key role in enhancing our understanding of the behavior of radioactive materials within living organisms in the field of nuclear medicine. However, detailed dosimetric d...
Authors: William G. Breen, Dalton Griner, Scott C Lester, Joseph John Lucido, Beth A. Schueler, Jack C. Thull
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Designing a total skin electron (TSE) beam therapy protocol requires finding the optimal balance between penetration depth, field uniformity, and x-ray contamination (XC). To better understan...