Authors: Tsuicheng D. Chiu, Strahinja Stojadinovic, Aaron Thomlinson, You Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose: Design and develop an automated verification and validation platform for the Elekta Leksell Gamma Knife (GK) Icon/Esprit High-Definition Motion Management (HDMM) system.
Methods: The H...
Authors: Shanli Ding, Osama R. Mawlawi, Tinsu Pan
Affiliation: UT MD Anderson Cancer Center
Abstract Preview: Purpose:
Reliable detection of anomalies in Gamma Camera/SPECT flood images is vital for quality assurance (QA). Traditional methods relying on numerical thresholds and manual inspections often mis...
Authors: Petr Bruza, Jeremy Eric Hallett, Brian W Pogue
Affiliation: Thayer School of Engineering, Dartmouth College, University of Wisconsin - Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: Cherenkov imaging is a powerful tool for localizing entrance and exit dose during radiotherapy treatment. The current implementation uses an intensified-CMOS (iCMOS) camera allowing for high-...
Authors: Steven Brown, Mike Hopkins, Jerimy C. Polf, Scott Sawyer, Benjamin L. Viglianti
Affiliation: H3D, inc, University of Michigan, M3D, Inc, M3D Imaging
Abstract Preview: Purpose: We characterized the sensitivity, energy dependence, and calibrated dose rate for a radiation imaging survey meter (RAVIN Cam; M3d inc., Ann Arbor MI) based on cadmium zinc telluride (CZT) cr...
Authors: Jorge Naoki Dominguez Kondo, Qihui Lyu
Affiliation: University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Targeted alpha therapy (TAT) has emerged as a highly potent therapeutic method in oncology, but its development is limited by the lack of imaging methods to quantify its dosimetry. Convent...
Authors: Alejandro Bertolet, Carlos Huesa-Berral, Victor V. Onecha
Affiliation: Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: Radioembolization for liver tumors using 90Y microspheres uses SPECT as confirmatory dosimetry, although 90Y is a pure β-emitter, and SPECT-imaging is only available through subsequent bremss...
Authors: Sam Beddar, Jason Michael Holmes, Daniel G. Robertson, James J. Sohn, Ethan D. Stolen
Affiliation: Department of Radiation Oncology, Mayo Clinic, MD Anderson Cancer Center, Department of Radiation & Cellular Oncology, University of Chicago, Department of Radiation and Cellular Oncology, University of Chicago
Abstract Preview: Purpose: Camera-based scintillation dosimetry incorporating large volumes have shown promise for fast and comprehensive evaluation of external beam treatment fields. While some efforts have been made ...
Authors: Ted Bartley, Steven Brown, Steven Chinn, Mike Hopkins, Stanley Leong, Jerimy C. Polf, Luke Rothermel, Scott Sawyer, Benjamin L. Viglianti
Affiliation: University of California School of Medicine, University of Michigan, H3D, inc, University Hospitals, M3D, Inc, M3D Imaging, California Pacific Medical Center
Abstract Preview: Purpose: In a collaboration between surgical oncologists and medical physicists, a new intra-operative gamma camera for imagining sentinel lymph nodes (SLN) during radio-guided SLN biopsy procedures h...
Authors: Jeremy Eric Hallett, Aubrey Parks, Brian W Pogue
Affiliation: University of Wisconsin - Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: Cherenkov imaging visualizes radiotherapy beams, assuming emission is proportional to deposited dose. However, attempts for Cherenkov as a quantitative dose estimation have been unsuccessful ...
Authors: Ananta Raj Chalise, Matthias K Gobbert, Zhuoran Jiang, Sina Mossahebi, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma, Jie Zhang
Affiliation: University of Maryland School of Medicine, University of Maryland Baltimore County, University of Maryland, Baltimore County, Stanford University, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc
Abstract Preview: Purpose: Prompt gamma (PG) imaging is a promising modality for proton dose verification. Currently, there is a lack of effective tool to investigate the PG emission during proton therapy and optimize ...
Authors: Alonso N. Gutierrez, Matthew D. Hall, Rupesh Kotecha, Yongsook C. Lee, Michael W. McDermott, Minesh P. Mehta, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose: The objective of this study is to systematically evaluate and validate the performance of a commercially available 3D Linear stage device as a quality assurance (QA) tool to validate position...
Authors: Zachary R. Grelewicz, Kevin C. Jones, Yixiang Liao, Andrew Ogilvy, Julius V. Turian
Affiliation: Rush University Medical Center
Abstract Preview: Purpose: To demonstrate the accuracy and QA application of a time-resolved 3D gamma camera, we measured the path traversed by the Ir-192 High-Dose-Rate (HDR) brachytherapy source passing through a rin...
Authors: Mostafa Cham, Matthias K Gobbert, Zhuoran Jiang, Sina Mossahebi, Ruth Obe, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma
Affiliation: University of Maryland School of Medicine, UMBC, University of Maryland Baltimore County, University of Maryland, Baltimore County, Stanford University, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc, Department of Infomation Systems, UMBC
Abstract Preview: Purpose: Compton camera (CC)-based prompt gamma imaging (PGI) offers real-time proton range verification. However, its limited-angle measurements cause severe distortions in PGI, affecting its clinica...
Authors: Nadège Anizan, David Broggio, Eric Chojnacki, Estelle Davesne, Didier Franck, Stéphanie Lamart, Alexandre Pignard
Affiliation: Institut Bergonié, Service de Physique Médicale, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSN-RES/SEMIA/LSMA
Abstract Preview: Purpose: To develop an innovative method enabling a comprehensive uncertainty budget associated to personalized absorbed doses for 177Lu-PSMA therapy and providing probability distributions of all dos...
Authors: Thomas R. Bortfeld, Prof. Elisabetta De Bernardi, Tianxue Du, Beatrice Foglia, Chiara Gianoli, Takamitsu Masuda, Katia Parodi, Marco Pinto, Boon-Keng Kevin Teo, Yunhe Xie
Affiliation: Department Of Radiation Oncology, Massachusetts General Hospital (MGH), School of Medicine and Surgery, University of Milano-Bicocca, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, National Institutes for Quantum Science and Technology (QST), University of Pennsylvania, Department of Experimental Physics - Medical Physics, Ludwig-Maximilians-Universität (LMU) München
Abstract Preview: Purpose: The full potential offered by protons in clinical practice is limited by range uncertainties. One possibility for monitoring is through secondary prompt gammas (PG). PG emission along the pen...
Authors: Louis Archambault, Nicolas Drouin, Alexis Horik, Simon Thibault
Affiliation: Département de Physique, de Génie Physique et D'optique, et Centre de Recherche sur le Cancer, Université Laval, Département de Physique, de Génie Physique et D'optique, et Centre d'optique, photonique et laser, Université Laval
Abstract Preview: Purpose: To develop a novel type of real-time 3D dosimeter for the quality assurance of linear accelerators used in external beam radiotherapy.
Methods: An experimental setup was constructed using ...
Authors: Ramesh Boggula, Jay W. Burmeister
Affiliation: Wayne State University, Karmanos Cancer Center, Gershenson ROC, Wayne State University School of Medicine
Abstract Preview: Purpose: This study evaluated the performance of a hybrid Compton camera for real-time imaging during the administration of Lu-177-based radiopharmaceuticals, including Pluvicto and Lutathera. The aim...
Authors: Lukas M. Carter, Jazmin Schwartz
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Accurate lung shunt fraction (LSF) estimation is essential for the safety and efficacy of 90Y-radioembolization therapy. This study compares planar gamma camera imaging and tomographic SPECT-...
Authors: Molokotima Kekana, Dennis S. Mackin, Stephen W. Peterson, Jerimy C. Polf
Affiliation: Department of Physics, University of Cape Town, M3D, Inc, The University of Texas MD Anderson Cancer Center, Houston
Abstract Preview: Purpose: To study the imaging characteristics of a prototype prompt gamma (PG) imaging system consisting of multiple rotating Compton cameras (CC).
Methods: The prototype CC imaging system is c...
Authors: Ananta Raj Chalise, Matthias K Gobbert, Hajar Moradmand, Sina Mossahebi, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma, Jie Zhang
Affiliation: University of Maryland School of Medicine, University of Maryland Baltimore County, University of Maryland, University of Maryland, Baltimore County, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc
Abstract Preview: Purpose: We are developing a novel Compton Camera (CC) system mounted orthogonally on the treatment nozzle for prompt gamma (PG) imaging-based proton range verification during treatment. This study in...
Authors: Robert A. Dahl
Affiliation: Mayo Foundation
Abstract Preview: Purpose: To develop tools to simplify/accelerate the quality assurance testing of the Mobetron mobile linear accelerator and increase safety when moving it to different OR’s.
Methods: The Mobet...
Authors: Mercy Iyabode Akerele, Yuni K. Dewaraja, Richard Laforest, Justin K. Mikell, Wendy Siman, Allan Thomas, Daniel Thorek
Affiliation: University of Michigan, Washington University School of Medicine in St. Louis, Washington University School of Medicine, University of Colorado Anschutz Medical Campus, School of Medicine, Washington University in St. Louis, Mallinckrodt Institute of Radiology, Washington University School of Medicine
Abstract Preview: Purpose: Post-therapy quantitative 90Y SPECT and PET measurements show ~25% lower activity than vendor-reported values for glass microspheres. We hypothesize this discrepancy is due to bremsstrahlung ...
Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital
Abstract Preview: Purpose: Frameless gamma knife (GK) treatments use a thermoplastic mask coupled with high-definition motion management system that utilizes an infrared camera, and a reflective marker placed on the pa...
Authors: Sharon L. White
Affiliation: University Of Alabama at Birmingham
Abstract Preview: N/A...