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Results for "group group": 196 found

3D Topological Features for Outcome Assessment of Therapeutic Responses to Neoadjuvant Chemoradiotherapy (NCRT) with and without Anti-CD40 Immunotherapy in Local Advanced Rectal Cancer (LARC)

Authors: Todd A Aguilera, Gaurav Khatri, Jiaqi Liu, Hao Peng, Nina N. Sanford, Robert Timmerman, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT southwestern medical center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
This study first integrates 3D topological data analysis with radiomics from local advanced rectal cancer T2-weighted MRI to evaluate therapeutic responses and quantify treatment-induced c...

A Bayesian Model for the Detection of Local Ventilation Changes in Lung Cancer Patients

Authors: Bas W. Raaymakers, Mario Ries, Paris Tzitzimpasis, Cornel Zachiu

Affiliation: Department of Radiotherapy, University Medical Center Utrecht, University Medical Center Utrecht, UMC Utrecht

Abstract Preview: Purpose: Radiation pneumonitis affects approximately 10-30% of lung cancer patients treated with radiation therapy (RT), posing a significant dose-limiting factor. Recently developed CT-ventilation me...

A Causal Machine Learning Analysis of Dosimetric and Clinical Predictors of Osteoradionecrosis in Head and Neck Cancer Radiotherapy

Authors: Jingyuan Chen, Sheng Li, Tianming Liu, Wei Liu, Zhengliang Liu, Zhong Liu, Daniel Ma, Samir H. Patel, Guangya Wang, Yunze Yang

Affiliation: University of Miami, Mayo Clinic, School of Data Science, University of Virginia, School of Computing, University of Georgia, Department of Radiation Oncology, Mayo Clinic, Institute of Western China Economic Research, Southwestern University of Finance and Economics

Abstract Preview: Purpose:
Traditional patient outcome analyses relied heavily on conventional statistical models that primarily elucidate correlation rather than causal relationships. In this study, we aim to ident...

A Clarification on the Bandwidth Difference Method for MRI B0 Homogeneity Assessment

Authors: Christina Brunnquell, Daniel Vergara, Joseph Everett Wishart

Affiliation: University of Minnesota, University of Washington

Abstract Preview: Purpose: To propose and validate a correction to the bandwidth difference method presented in Task Group Report No. 325 for quantifying static magnetic field homogeneity (ΔB0).
Methods: A clarifica...

A Clinical Evaluation of Two Commercially Available Deep-Learning Algorithms for Automated Organs at Risk Contouring

Authors: Steven DiBiase, Gurtej S. Gill, Haohua Billy Huang, Nicholas J. Lavini, Luxshan Shanmugarajah, Salar Souri, Samantha Wong

Affiliation: Stony Brook University, Northwell Health, Cornell University, NewYork-Presbyterian, New York-Presbyterian

Abstract Preview: Purpose: Clinical applications of deep learning-based algorithms have come to the radiation oncology field as organ at risk (OAR) auto contouring programs. We evaluated two of these algorithms’ (Radfo...

A Comparative Analysis of the Dosimetric, Alignment, and Setup Efficiency in Left Breast Cancer Radiotherapy Treated with Dibh Using ABC and Sgrt

Authors: Aaron Conard, Victoria Croog, Marie Gurka, Lan Lin

Affiliation: Johns Hopkins University

Abstract Preview: Purpose:
This study evaluates the utility of the Active Breathing Coordinator (ABC) and Surface Guided Radiation Therapy (SGRT) techniques in implementing Deep Inspiration Breath Hold (DIBH) for le...

A Motion Analysis of Cardiac Substructures for Guiding Stereotactic Arrhythmia Radiotherapy Motion Management

Authors: Hongyu An, Phillip Cuculich, H Michael Gach, Yao Hao, Trevor McKeown, Clifford Robinson, Yuhao Wang, Deshan Yang

Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, Duke University, Department of Radiation Oncology, Duke University, Washington University in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis

Abstract Preview: Purpose: This study investigated cardiac motion characteristics of ventricular tachycardia patients to support patient-specific motion management for stereotactic arrhythmia radiotherapy (STAR) treatm...

A Multi-Regional and Multi-Omics Approach to Predict Penumonitis in Patients with Locally Advanced Non-Small Cell Lung Cancer in Nrg Oncology Trial RTOG 0617

Authors: Katelyn M. Atkins, Indrin J. Chetty, Elizabeth M. McKenzie, Taman Upadhaya, Samuel C. Zhang

Affiliation: Department of Radiation Oncology,Cedars-Sinai Medical Center, Cedars-Sinai Medical Center

Abstract Preview: Purpose:
We explored a multi-regional and multi-omics approach to extract CT-based radiomics and 3D dosiomics features to predict radiation pneumonitis (RP) in patients with locally advanced Non-Sm...

A National Guide for Managing Multidisciplinary Groups to Implement Patient Safety in the Areas of Medical Use of Ionizing Radiation

Authors: Merce Beltran Vilagrasa, Nuria Jornet, Cristina Moreno Saiz, Maria Pinto Monedero, Carlos Prieto Martín, María José Rot San Juan, Pablo Saldaña Gutierrez, Agustin Santos

Affiliation: Servicio de Radiofísica Hospitalaria, Hospital Universitario Clínico San Cecilio, Servicio de Radiofísica y Protección Radiológica, Consorcio Hospitalario Provincial de Castellón, Servicio de Radiofísica y Protección Radiológica. Hospital Universitario de la Princesa, Servicio de Física Médica y Protección Radiológica, Instituto Catalán de Oncología/Hospital Universitario de Bellvitge, Servei de Física i Protecció Radiològica. Hospital Universitari Vall d'Hebron, Servei de Radiofísica i Radioprotecció. Hospital de la Santa Creu i Sant Pau, Servicio de Radiofísica y Protección Radiológica, Hospital Universitario Puerta de Hierro, Servicio de Radiofísica Hospitalaria, Hospital Universitario 12 de Octubre

Abstract Preview: Purpose: Patient safety (PS) is a discipline that is not usually included in the training curricula of medical physics experts in many countries. This implies that PS is addressed by professional soci...

A Novel Feature Selection Method for Survival Prediction of Head-and-Neck Following Radiation Therapy

Authors: Xiaoying Pan, X. Sharon Qi

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, School of Computer Science and technology,Xi'an University of Posts and Telecommunications

Abstract Preview: Purpose:
Survival prediction for cancer presents a substantial hurdle in personalized oncology, due to intricate, high-dimensional medical data. Our study introduces an innovative feature selection...

A Novel Group-Wise Non-Rigid Iterative Closest Point Shape Registration Algorithm with Temporal Smoothness Regularizations for Computing the Respiratory Motion of the Heart in Respiratory 4DCTs and Avoiding Random Cardiac Motion Artifacts

Authors: Hongyu An, Phillip Cuculich, H Michael Gach, Yao Hao, Trevor McKeown, Clifford Robinson, Yuhao Wang, Deshan Yang

Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, Duke University, Department of Radiation Oncology, Duke University, Washington University in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis

Abstract Preview: Purpose: Cardiorespiratory motion management is crucial in stereotactic arrhythmia radiotherapy to define target margins and minimize cardiac toxicity. While respiratory 4DCT (r4DCT) images can infer ...

A Novel Groupwise Shape Deformable Registration Algorithm to Quantify the Respiratory Motion of the Heart in Respiratory 4DCTs While Accounting for Random Cardiac Motion Artifacts in the Respiratory 4DCTs

Authors: Anna E. Rodrigues, Yuhao Wang, Deshan Yang

Affiliation: Duke University, Department of Radiation Oncology, Duke University

Abstract Preview: Purpose: Accurate motion margin definition in StereoTactic Arrhythmia Radiotherapy (STAR) requires accurate cardiorespiratory motion assessment. However, respiratory 4DCT (r4DCT) images are affected b...

A Novel Margin-Based Focal Distance Loss for Lesion Segmentation in Medical Imaging

Authors: Weiguo Lu, Hua-Chieh Shao, Guoping Xu, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Neural network-based lesion segmentation remains a significant challenge due to the low contrast between lesions and surrounding tissues (high ambiguity) and the variability of lesion shap...

A Pilot Survey on Medical Physics Residency Education in External Beam Special Procedures

Authors: Courtney R. Buckey, Jay W. Burmeister, Minsong Cao, Grace Chang, Yu Kuang, Yixiang Liao, Yi Rong, Dandan Zheng

Affiliation: Mayo Clinic, Mayo Clinic Arizona, Karmanos Cancer Center, Gershenson ROC, Wayne State University School of Medicine, Department of Radiation Oncology, University of California, Los Angeles, Medical Physics Program, University of Nevada, Rush University Medical Center, University of Rochester

Abstract Preview: Purpose: Investigate the adequacy of training for therapeutic medical physics residents in select special procedures.
Methods: After a review of existing literature, a multi-institutional group dev...

A Real-Time Framework for Fiducial Tracking and Intrafraction Motion Assessment of Cyberknife in Stereotactic Body Radiation Therapy for Liver Cancer

Authors: Ruiyan Du, Mingzhu Li, Ying Li, Wei Liu, Shihuan Qin, Yiming Ren, Biao Tu, Hui Xu, Lian Zhang, Xiao Zhang, Zengren Zhao

Affiliation: Department of General Surgery, Hebei Key Laboratory of Colorectal Cancer Precision Diagnosis and Treatment, The First Hospital of Hebei Medical University, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Mayo Clinic, Department of Oncology, The First Hospital of Hebei Medical University

Abstract Preview: Purpose: Fiducial tracking is widely used in CyberKnife to dynamically guide the gantry for moving target like liver cancer stereotactic body radiation therapy (SBRT). This study developed a robust fr...

A Risk Assessment Approach to Photon Reference Dosimetry Using TG-100 Methodology

Authors: Ila Farhang, Ryan D. Foster, Devin Heitz, Jordan B Lunsford, Ashkan Shafiee

Affiliation: Atrium Health Wake Forest Baptist, Atrium Health/LCI Cabarrus

Abstract Preview: Purpose: American Association of Physicists in Medicine (AAPM) Task Group (TG) -51 is a widely utilized protocol for the absolute calibration of linear accelerators. The purpose of this project was fo...

A Simplified, Rigorous Procedure for Ultrasound Quality Assurance

Authors: Paul L. Carson, Sander Dekker, Stephen Z Pinter, Megan K. Russ

Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, University of Michigan, Cablon Medical B.V., Univ of Michigan, Dept. of Radiology

Abstract Preview: Purpose:
To promote a simplified, inexpensive, but rigorous set of ultrasound QA tests and to evaluate their potential using a Randomly-placed very Hypoechoic Sphere Phantom (RHSP) in comparison to...

AI-Driven Drug Discovery through an Interactive Analysis of Radiomics and Biological Insights in Glioblastoma

Authors: Nobuki Imano, Yuzuha Kadooka, Daisuke Kawahara, Misato Kishi, Yuji Murakami, Shumpei Onishi

Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Neurosurgery, Hiroshima University Hospital

Abstract Preview: Purpose: Radiomics has proven useful in predicting overall survival in glioblastoma (GBM) patients, but consistent molecular correlations remain unidentified, leaving its biological basis unclear. Thi...

Accuracy Analysis of "Sphere-Mask" Optical Positioning System in Radiotherapy of Breast Cancer

Authors: Xiu tong Lin, Tao Sun

Affiliation: Department of Radiation physics and technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation physics and technology, Shandong Second Provincial General Hospital

Abstract Preview: Purpose: To compare the positioning accuracy and time efficiency of "Sphere-Mask" Optical Positioning System (OPS) and traditional laser light positioning method in breast cancer radiotherapy, and to ...

Acute Workforce Shortages and Potential Solutions through Expanded Residency Training Infrastructure

Authors: Hania A. Al-Hallaq, Abby E. Besemer, Jay W. Burmeister, Jessica Fagerstrom, Kristi Rae Gayle Hendrickson, Neil A. Kirby, Christine M. Swanson, Christopher Watchman, Brian D Wichman

Affiliation: University of Wisconsin-Madison Department of Medical Physics, University of Washington, University of Louisville Brown Cancer Center, Banner, Karmanos Cancer Center, Gershenson ROC, Wayne State University School of Medicine, US Oncology, UT Health San Antonio, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: To address the acute workforce shortage in medical physics by presenting a novel residency expansion model leveraging existing CAMPEP-accredited infrastructure and partnerships with underserv...

Advanced Skeletal Models for Icrp Reference Pediatric Individuals: Development and Dosimetric Implications

Authors: Wesley E. Bolch, Chansoo Choi, Robert Joseph Dawson, Bangho Shin, Yitian Wang

Affiliation: University of Florida

Abstract Preview: Purpose: The skeleton plays a critical role in dosimetry, containing red bone marrow (RBM) and bone endosteum (BE), which are closely linked to radiation-induced leukemia and bone cancer. While severa...

Advancements and Cost-Effectiveness of Proton Therapy in the Global Oncology Landscape

Authors: Aman Anand, Jonathan B. Ashman, Martin Bues, Brady S. Laughlin, Lisa McGee, Justin Pettit, Fan Yang, Libing Zhu

Affiliation: Department of Radiation Oncology Mayo Clinic, Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose: Proton therapy (PT) offers significant clinical and economic benefits across various cancers, whereas it also has faced skepticism due to its historically high costs and perceived overuse in ...

Advancing the Evaluation of Radiation-Induced Vaginal Toxicity Using Ultrasound Radiomics: Phantom Validation and Pilot Clinical Study

Authors: Himanshu Joshi, Tian Liu, Deborah C Marshall, Joseph Shelton, Jing Wang, Xiaofeng Yang, Emi Yoshida, Boran Zhou

Affiliation: Department of Radiation Oncology, Baylor College of Medicine, Icahn School of Medicine at Mount Sinai, Emory University, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, University of California, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Radiation-induced long-term toxicities, such as vaginal stenosis, significantly impact the quality of life for patients undergoing pelvic radiotherapy (RT) for gynecologic (GYN) malignancies....

An Automated Solution to Staged Treatments for Arteriovenous Malformations in Gammaknife

Authors: Strahinja Stojadinovic, Robert Timmerman, Yulong Yan

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas Southwestern Medical Center, University of Texas Southwestern Medical Center

Abstract Preview: Purpose: Radiosurgery for large (>10cc) arteriovenous malformations (AVMs) poses significant challenges due to increased risks of complications and lower obliteration rates. To mitigate toxicity, larg...

An Automated Tool for the Categorization of a Clinical Database By Anatomic Region for Big Data Applications

Authors: Yasin Abdulkadir, Justin Hink, James M. Lamb, Jack Neylon

Affiliation: Department of Radiation Oncology, University of California, Los Angeles

Abstract Preview: Purpose: Curation remains a significant barrier to the use of ‘big data’ radiotherapy planning databases of 100,000 patients or more. Anatomic site of treatment is an important stratification for almo...

An Energy Layer Optimization Approach for Spot Scanning Proton Arc Therapy

Authors: Wenhua Cao, Hadis Moazami Goudarzi, Madison Emily Grayson, Zongsheng Hu, Gino Lim, Steven Hsesheng Lin, Radhe Mohan

Affiliation: The University of Texas MD Anderson Cancer Center, Department of Industrial Engineering, University of Houston, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Proton Arc Therapy (PAT) offers significant potential in treating complex cancer cases by delivering a continuous radiation dose as the gantry rotates. This study aims to investigate the pote...

An Explainable Classifier for Enhancing the Quality Assurance of Digital Breast Tomosynthesis Phantom Images

Authors: Hui-Shan Jian, Yu-Ying Lin

Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou

Abstract Preview: Purpose: The image quality assurance of mammographic images is crucial for correct diagnosis. To develop and validate an explainable deep-learning classifier for phantom image quality assessment of di...

An Investigational, or-Based Imaging Method for Reconstructing Catheters in Image-Guided HDR Brachytherapy

Authors: Margaret Cunningham Barker, Michael E. Campbell, Peyman Kabolizadeh, A. Nisar Syed, Randy Wei, Lisa M. Wilson-Turner

Affiliation: Memorial Radiation Oncology Medical Group, MemorialCare Todd Cancer Institute

Abstract Preview: Purpose:
Interstitial HDR treatment planning can be time-consuming, with substantial time spent waiting for the patient’s arrival and performing manual tasks, such as contouring ROIs and catheter r...

An OAR Margin Recipe Based on Clinical Data and Including Radio-Sensitivity Variation

Authors: Carlo Greco, Joep Stroom, Sandra Vieira

Affiliation: Champalimaud Center for the Unknown

Abstract Preview: Purpose: RTP safety margins are generally based on geometrical uncertainties alone and not directly on clinical outcome. Here we use clinical dose-constraint data to generate dosimetric margins for OA...

An Ultra-High Parallel Performance (UHPP) Framework for Highly Complex Radiotherapy Planning

Authors: Lu Jiang, Shusen Jing, Qihui Lyu, Dan Ruan, Ke Sheng, Qifan Xu

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose: In radiotherapy, the conformity and compactness of dose distribution are vital to patient outcomes. The introduction of highly complex planning, such as 4π radiotherapy, has provided a system...

Analysis of Inter-Organ Noise Variability for Clinical CT Images across 3133 Image Series

Authors: Lavsen Dahal, Francesco Ria, Ehsan Samei, Justin B. Solomon, Liesbeth Vancoillie, Yakun Zhang

Affiliation: Duke University, Carilion Clinic, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Clinical diagnostic task-based optimization of CT procedures require precise and organ-specific assessments. This study investigates inter-organ noise variability to highlight the limitations...

Anatomical Noise Power Exponent (β) As an Image-Based Risk Factor for Breast Cancer

Authors: Yile Fang, Leslie Lamb, Nathaniel David Mercaldo, Kai Yang

Affiliation: Massachusetts General Hospital

Abstract Preview: Purpose: To quantitatively evaluate power-law exponent β as a potential image-based breast cancer risk factor.

Methods: Two groups of breast cancer screening cohorts (target vs. control, 20 sub...

Application of 3D Printed Individualized Applicators Based on Pre-Planning in Interstitial Brachytherapy for Cervical Cancer

Authors: Zhitao Dai

Affiliation: Chinese Academy of Medical Sciences Cancer Hospital Shenzhen Hospital

Abstract Preview: Purpose: To investigate the accuracy of 3D printed individualized vaginal template assisted pre-planning in the interstitial implantation of cervical cancer, to examine the advantages when compared wi...

Assessing Accessibility for the Visually Impaired in Medical Physics Training

Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Maximilian Stephen Meineke, Runhe Tan

Affiliation: The Ohio State University James Cancer Hospital, The James Cancer Center, The Ohio State University, The Ohio State University - James Cancer Hospital

Abstract Preview: Purpose: Accessibility is a topic of increasing importance in many fields, and medical physics is no exception. While the traditional educational pathway presents a plethora of challenges for the visu...

Assessing Breast Cancer Tumor Segmentability on an Investigational, Double-Bolus, Prone-to-Supine Breast MRI Protocol for Surgical Guidance.

Authors: Richard J Barth, Brook Kennedy Byrd, Roberta DiFlorio-Alexander, Misty J Fox, Venkat Krishnaswamy, Keith D. Paulsen, Timothy B Rooney

Affiliation: Cairn Surgical Inc., Dartmouth Health, Thayer School of Engineering, Dartmouth Hitchcock Medical Center, University of Virginia Health, CairnSurgical Inc.

Abstract Preview: Purpose: Supine breast MRI enables precise surgical planning with demonstrated benefit in decreasing positive margin rates during BCS. However, acquiring supine breast MRI scans in a secondary imaging...

Assessing Skin Microcirculation in Breast Cancer Radiotherapy: Effectiveness of a Specialized Bra Compared in Two Hypofractionated Protocols.

Authors: Rosa Maria Cibrián Ortiz de Anda, Altea C Esteve, Carlos M Galindo-González, Carmen C García, Amparo Gonzalez-Sanchis, Jose C Gordo-Partearroyo, Emilio Soria-Olivas, Javier Vijande

Affiliation: IFIC-UV, Valencia University, Hospital General Universitario

Abstract Preview: Purpose: To determine how skin microcirculation is affected by the two hypo-fractionated radiotherapy protocols in breast cancer patients using Laser Doppler Imaging, a non-invasive method for assessi...

Assessing the Potential of Virtual Grid Portable Radiographic Systems for Radiation Dose Reduction: A Comparative Evaluation of Deviation Index in Abdominal Imaging

Authors: Gary Y. Ge, Azmul Siddique, Jie Zhang

Affiliation: Department of Radiology, University of Kentucky, University of Kentucky

Abstract Preview: Purpose: Virtual grid technology addresses scattered radiation without a physical grid, offering the potential to reduce patient radiation dose while maintaining image quality. However, this potential...

Assessment of the Impact of CT Respiratory Motion on PET SUV Quantification through Virtual Imaging

Authors: Ehsan Abadi, Darrin Byrd, Paul E. Kinahan, Katie Marie Olivas, Ehsan Samei

Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, University of Washington

Abstract Preview: Purpose: To evaluate the impact of respiratory motion during CT acquisitions on PET image quantification using an integrated PET-CT simulation pipeline.
Methods: A validated CT simulator (DukeSim) ...

Attention-Based Multiple Instance Learning of Head and Neck Cancer Grading on Digital Pathology Using Vision-Language Foundational Models

Authors: Kyle J. Lafata, Xiang Li, Megan K. Russ, Zion Sheng

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: To adapt Vision-Language Foundational Models (VLFM) to perform HNSCC tumor grading on H&E whole slide images (WSI) via attention-based multiple instance learning (ABMIL).
Methods: We utili...

Augmenting Histopathology Lymphocyte Detection with Gpt-4 in-Context Visual Reasoning

Authors: Kyle J. Lafata, Casey Y. Lee, Xiang Li, Megan K. Russ, Zion Sheng

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose:
Traditional deep learning-based cell segmentation models face limitations, such as the need for extensive training data and retraining when encountering new cell types or domains. This stu...

Automated Case Prioritization in Breast Radiation Therapy Peer Review Rounds

Authors: Leigh A. Conroy, Thomas G Purdie, Christy Wong

Affiliation: Department of Medical Biophysics, University of Toronto, Princess Margaret Cancer Centre

Abstract Preview: Purpose: To develop a novel machine learning (ML) algorithm to evaluate and rank breast radiation therapy (RT) treatment plans based on treatment complexity for prioritization in multidisciplinary pee...

Automatic Contour Quality Assurance Using Deep-Learning Based Contours

Authors: Laurence Edward Court, Raphael Douglas, David Fuentes, Anuja Jhingran, Barbara Marquez, Raymond Mumme, Christine Peterson, Julianne M. Pollard-Larkin, Surendra Prajapati, Dong Joo Rhee, Thomas J. Whitaker

Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Safe deployment of auto-contouring models requires the inclusion of automated quality assurance (QA). One approach is to use an independent auto-contouring model and compare the contours geom...

BEST IN PHYSICS THERAPY: Impact of Local Tissue Oxygenation Level on the Flash Effect in Murine Skin

Authors: David J. Gladstone, P. Jack Hoopes, David I Hunter, Brian W Pogue, Jacob Pierce Sunnerberg, Armin Tavakkoli

Affiliation: Thayer School of Engineering, Dartmouth College, University of Wisconsin - Madison, Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Geisel School of Medicine, Dartmouth College

Abstract Preview: Purpose: The FLASH effect, characterized by normal tissue sparing under ultra-high dose rate (UHDR) radiation delivery, remains mechanistically unclear. This study investigated the relationship betwee...

Brachyplancheck: An Independent Monte Carlo Dose Calculation Tool for Brachytherapy Using Egs_Brachy

Authors: Amy Tien Yee Chang, Chi Wai Cheung, Tin Lok Chiu, Chen-Yu Huang, Chi Wa Kong, Pei-Xiong Li, Pak Hang Nam, Bin Yang, Siu Ki Yu

Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital

Abstract Preview: Purpose: This study introduces BrachyPlanCheck, an independent Monte Carlo (MC)-based dose calculation tool for 192Ir brachytherapy retrospective study or algorithm commissioning.
Methods: BrachyPl...

Brain Structural Covariance Networks in Nicotine-Dependent Users: A Graph Analysis

Authors: Humberto Monsivais, Brian A. Taylor, Francesco Versace

Affiliation: Purdue University, Department of Behavioral Science, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: To identify possible signatures of altered brain morphometry in nicotine-dependency via a structural covariance network approach.

Methods: Fifty-one healthy controls (HC:27M, mean age=...

Bridging the Gap of Radiotherapy Planning Quality between a High-Income Countrie to a Middle-Income Country By the Dosimetric Validation of a KBP Model Vs Junior, Senior Dosimetrists and MCO Planning

Authors: Eduardo Florian, Hiram Gay, Geoffrey D. Hugo, Otto Hurtarte, Milton Ixquiac, Erick Orlando Montenegro, Franky Eduardo Reyes, Francisco Javier Reynoso, Edgar Aparicio Ruiz, Baozhou Sun, Jacaranda Van Rheenen, Kevin Vega, Angel Velarde, Vicky de Falla

Affiliation: WashU Medicine, Liga Nacional Contra el Cancer, Liga Nacional Contra el Cancer/INCAN, Liga Nacional Contra el Cancer / INCAN, Liga Nacional Contra el Cancer and Universidad de San Carlos de Guatemala, Washington Univ. in St. Louis, Liga Nacional Contra el Cáncer / INCAN, Washington University in St. Louis, Varian, Baylor College of Medicine

Abstract Preview: Purpose:
IMRT has become the standard of care in high-income countries (HICs) due to reduced toxicity and improved treatment outcomes.
The purpose of this work is validating the KBP model shared...

CBCT-Based Radiomics of Head and Neck Cancer for Predicting Patient Toxicity to Radiotherapy

Authors: Rodrigo Delgadillo, Nesrin Dogan, Benjamin J. Rich, Stuart E Samuels, Levent Sensoy

Affiliation: University of Miami Sylvester Comprehensive Cancer Center

Abstract Preview: Purpose: Daily Cone beam CT (CBCT) images may be useful in detecting early morphological changes during head and neck cancer radiotherapy. The aim of this study was to evaluate the performance of CBCT...

Can AI-Based Llms be Your Study Buddy for ABR Professional Exams?

Authors: Arjit K. Baghwala, Sunan Cui, Jessica Fagerstrom, Eric C. Ford, Kristi Rae Gayle Hendrickson, Sharareh Koufigar, Samuel Ming Ho Luk, Bishwambhar Sengupta, Afua A. Yorke

Affiliation: University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, University of Vermont Medical Center, University of Washington and Fred Hutchinson Cancer Center, Houston Methodist Hospital

Abstract Preview: Purpose: The global burden of cancer continues to rise, leading to an increased workload in radiation oncology clinics. This surge is not only due to the growing demand for treatment machines and moda...

Can Regional Radiomic Features from Pre-Treatment Computed Tomography Serve As Biomarkers for Predicting Radiation Pneumonitis?

Authors: David J. Carlson, Ming Chao, Tian Liu, Yong Hum Na, Kenneth E Rosenzweig, Robert Samstein, Lewis Tomalin

Affiliation: Icahn School of Medicine at Mount Sinai, Yale University School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: To investigate the potential of regional radiomic features extracted from five lung sub-lobes on pre-treatment CT as biomarkers for predicting radiation pneumonitis (RP) using machine learnin...

Comparing Planned Vs. Delivered Bladder Dose-Toxicity Associations in Prostate Cancer Radiotherapy: Insights from the Mirage Trial

Authors: Minsong Cao, Amar Kishan, Yi Lao, An Liu, Beth Neilsen, X. Sharon Qi, Kun Qing, Ke Sheng, Michael Steinberg, Luca F Valle, Terence Williams

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiation Oncology, City of Hope Medical Center, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, City of Hope National Medical Center

Abstract Preview: Purpose: To investigate the clinical relevance of planned versus delivered doses in toxicity associations utilizing localized assessment of genitourinary (GU) toxicity in bladder subregions among pros...

Comprehensive Assessment of Intra-Fractional and Inter-Fractional Motion in Intensity-Modulated Proton Therapy for Esophageal Cancer

Authors: Tianyuan Dai, Xiaoying Fan, Shuting Wang, Yong Yin

Affiliation: Department of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences

Abstract Preview: Purpose: The purpose of this study was to investigate the interplay effect during intra-fractional motion and the effect of the robust optimization parameters for inter-fractional motion in the intens...

Computed Tomography Organ Dose Library Derived from Newly Developed Newborn-Infant-Toddler Computational Phantoms

Authors: Jared Baggett, Wesley E. Bolch, Lukas M. Carter, Robert Joseph Dawson, Laura Dinwiddie, Adam Leon Kesner, Cameron B. Kofler, Juan Camilo Ocampo Ramos, Yitian Wang, Stefan Wehmeier

Affiliation: University of Chicago, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, University of Florida, MD Anderson

Abstract Preview: Purpose: To develop a slice-specific computed tomography (CT) organ dose library using Monte Carlo radiation transport simulations on a newly created set of newborn, infant, and toddler computational ...

Consecutive Daily Fractions with Itv Boost Are Safe for Treating Central Non-Small Cell Lung Cancer Using Stereotactic Body Radiation.

Authors: Baher Elgohari, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Jeonghoon Park, Tyler Wilhite

Affiliation: UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, UPMC Hillman Cancer Center, UPMC, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose:
To compare toxicity between consecutive-daily (QD) with every-other-day (QoD) delivery of lung stereotactic-body-radiation (SBRT) for central non-small-cell lung cancer (NSCLC).
Methods...

Contrast Volume Prediction Using CT Dose Metrics

Authors: Niki Fitousi, Anna Romanyukha, Stuart Utting

Affiliation: University Hospitals Dorset, Qaelum NV

Abstract Preview: Purpose:
For increased patient safety and with a focus on sustainability in the radiology department, efforts are being made to optimize contrast media usage. In this study, the possibility of util...

Correcting for Lung Ventilation in Model-Based CT

Authors: Ryan Andosca, Igor Barjaktarevic, Peter Boyle, Jie Deng, Minji Victoria Kim, Michael Vincent Lauria, Daniel A. Low, Claudia R. Miller, Drew Moghanaki, Louise Naumann, Jack Neylon, Dylan P. O'Connell, Ricky R Savjani

Affiliation: Department of Pulmonology, University of California Los Angeles, University of California, Los Angeles, Department of Radiation Oncology, University of California, Los Angeles, UCLA, UCLA Radiation Oncology

Abstract Preview: Purpose: To develop a Hounsfield Unit ventilation-based correction method for use with model-based CT when used as a replacement for 4DCT.
Methods: The model-based CT we employ is termed 5DCT, whic...

Cross-Calibration and Comparison of CT Number to Electron Density Using Two Calibration Phantoms

Authors: Afrouz Ataei, Xinhui Duan, Andrew R. Godley, Mi-Ae Park, Mahbubur Rahman, Liqiang Ren, Chenyang Shen, Gary Xu

Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University, Imaging Services, UT Southwestern Medical Center

Abstract Preview: Purpose:
Electron density (ED) phantoms are crucial for calibrating CT number (HU) to relative ED in treatment planning. This study evaluates the differences in HU-to-ED calibrations between two co...

Deep Learning-Based Multileaf Collimator Sequence Prediction for Automated VMAT Treatment Planning in Pancreatic Cancer

Authors: Zixu Guan, Takahiro Iwai, Takashi Mizowaki, Mitsuhiro Nakamura, Michio Yoshimura

Affiliation: Kyoto University, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University

Abstract Preview: Purpose:
The goal of this study is to develop a fully automated treatment planning approach for VMAT in pancreatic cancer that can convert patient anatomy into LINAC machine parameters. In this wor...

Deep-Learning Based Spectral Artifact Removal with In Vivo 7T Proton MRSI Data

Authors: Anke Henning, Mahrshi Jani, Tianyu Wang, Andrew Wright, Xinyu Zhang

Affiliation: Advanced Imaging Research Center (AIRC), UT Southwestern Medical Center

Abstract Preview: Purpose: Proton MRSI offers critical metabolic insights into diseased brain processes but is prone to artifacts, and current post-processing methods are often insufficient, resulting in low-quality da...

Design and Implementation of a Dedicated Ethics and Professionalism Course for a Campep Accredited Graduate Program in Medical Physics

Authors: Jenghwa Chang, Marissa Joyce Vaccarelli

Affiliation: Northwell, Hofstra University Medical Physics Program

Abstract Preview: Purpose: Our University has a CAMPEP-accredited Master of Science (MS) in Medical Physics program with an established curriculum. Prior, ethics and professionalism themes were taught in an introductor...

Designing Impactful Radiotherapy Training for Skill Development and Long-Term Growth

Authors: Stephanie Bennett, Sean L. Berry, Caroline M. Colbert, Dustin J. Jacqmin, James A. Kavanaugh, Minsun Kim, Maura L. Kirk, Emily Kruse, Benjamin Li, Mu-Han Lin, Lindsey A. Olsen, Jose Carlos Pichardo, Justin R. Roper, Leah K. Schubert, Chunhao Wang, Sua Yoo

Affiliation: University of Wisconsin, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation & Cellular Oncology, University of Chicago, Abington - Jefferson Health, Mayo Clinic, University of Washington, University of Colorado Health, University of Colorado Denver, Department of Radiation Oncology, University of Washington and Fred Hutch Cancer Center, Duke University, Pichardo Physics LLC, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: As clinics in lower- and middle-income countries (LMICs) transition to advanced radiotherapy techniques like IMRT and VMAT, gaps in training can result in suboptimal planning. To help support...

Development of Foundation Model for Analysis of Prostate Cancer with Mpmri

Authors: Ahmad Algohary, Adrian Breto, Quadre Emery, Radka Stoyanova

Affiliation: University of Miami, Department of Radiation Oncology, University of Miami

Abstract Preview: Purpose:
To develop a foundation model (U-Found) for multiparametric MRI (mpMRI) of the prostate by using self-supervised learning to prove the feasibility of a prostate-oriented foundation model u...

Development of a Method to Standardize Multi-Institutional Quality Assurance Data through an AI Based Language Model Ontology.

Authors: Rafe A. McBeth, Ayoola Okuribido, Rodney D. Wiersma

Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, UCLA

Abstract Preview: Purpose: To develop a method for standardizing data collected during quality assurance checks across institutions using language models.
Background: QA procedures and data management can vary widel...

Development of a Method to Standardize Multi-Instiutional Quality Assurance Data through an AI Based Language Model Ontology.

Authors: Rafe A. McBeth, Ayoola Okuribido, Rodney D. Wiersma

Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, UCLA

Abstract Preview: Purpose: To develop a method for standardizing data collected during quality assurance checks across institutions using language models.
Background: QA procedures and data management can vary widel...

Development of a Robust 3D-Ultrasound (3DUS) Quality Assurance (QA) Framework for a Real-Time Needle-Tracking System in HDR GYN Brachytherapy

Authors: Diandra Ayala-Peacock, Lindsey Hendricks Bloom, Oana I. Craciunescu, Julie A. Raffi, Megan K. Russ, Ryan Sanford, Rajesh Venkarataman

Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, Duke University Medical Center, Duke University, Eigen Health, Duke Univesity

Abstract Preview: Purpose: To establish a robust QA framework to characterize and ensure accuracy, reliability, and reusability of a transrectal ultrasound (TRUS)-based needle tracking system (NTS) for clinical HDR GYN...

Development of an MRI Guided Precision Small Animal Radiotherapy System

Authors: Yaowen Cao, Yunwen Huang, Yidong Yang, Xiaogang Yuan, Ning Zhao, Cheng Zheng

Affiliation: Department of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China

Abstract Preview: Purpose: MRI has better soft tissue contrast than cone beam CT which is commonly used in image guided radiotherapy. This study aims to develop a low-field MRI system for precision small animal radiati...

Difference in Image Quality between Natively Reconstructed and PACS Reformatted CT Images

Authors: Beth Reed, Justin B. Solomon

Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: The purpose of this study was to compare image quality between CT images of variable slice thickness reconstructed directly at the scanner verses reformatted at a PACS workstation.
Methods...

Direct Measurement of DNA Damage to Determine Dose and Biological Effectiveness

Authors: Michael Lamontagne, Ileana Pazos, Jerimy C. Polf, Joseph W. Robertson, Teniola Tobun, Ronald E. Tosh, Michael Zwolak

Affiliation: Biophysics and Biomedical Research Group, Microsystems and Nanotechnology Division, National Institute of Standards and Technology, M3D, Inc, National Institute of Standards and Technology, Dosimetry Group, Radiation Physics Division, National Institute of Standards and Technology

Abstract Preview: Purpose: To study how damage to DNA molecules increases and changes as a function of the type and dose of radiation.

Methods: DNA molecules of a known length (number of base pairs (BP)) within ...

Do We Need Pediatric-Specific Models for Radiotherapy Auto-Contouring? a Comparative Study of Pediatric and Adult-Trained Tools

Authors: Gregory T. Armstrong, James E. Bates, Christine V. Chung, Lei Dong, Ralph Ermoian, Jie Fu, Christine Hill-Kayser, Rebecca M. Howell, Meena S. Khan, Sharareh Koufigar, John T. Lucas, Thomas E. Merchant, Taylor Meyers, Tucker J. Netherton, Constance A. Owens, Arnold C. Paulino, Sogand Sadeghi

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, St. Jude Children's Research Hospital, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, St. Jude Children’s Research Hospital, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, University of Washington/ Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences

Abstract Preview: Purpose: Clinical workflows often rely on auto-segmentation tools trained on adult data, which may exhibit suboptimal performance in pediatric imaging due to inherent anatomical variations and smaller...

Does the Method Matter? How in Hominum, In Vivo, in silico, and in Phantasma Measures Compare and Contrast Is Assessing the Utility of Photon Counting CT?

Authors: Ehsan Abadi, Njood Alsaihati, Steven T. Bache, Mridul Bhattarai, Cindy Marie McCabe, Francesco Ria, Ehsan Samei

Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Duke University Health System, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: To compare and contrast alternative methods including reader (in hominum), phantom (in phantasma), in vivo, and in silico methods deployed to assess the performance of photon counting (PCCT) ...

Dosimetric Analysis of Lymphopenia after Lung Irradiation and Modeling the Probability of Normal Tissue Complications

Authors: Tianyuan Dai, Xiaoying Fan, Shuting Wang, Yong Yin

Affiliation: Department of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences

Abstract Preview: Purpose: Decreased lymphocytes increase the risk of infections and other problems. Radiation exposure can cause the development of severe lymphopenia. In this study, we used a dynamic blood flow model...

Dosimetric Assessment of Multicriteria Optimization for Accelerated Partial Breast Irradiation (APBI)

Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan

Affiliation: Medical University of South Carolina

Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...

Dosimetric Impact of Adaptive Radiotherapy with Ethos for Prostate Cancer: Localized Analysis of Bladder and Rectum across Planned, Non-Adaptive Accumulated, and Adapted Treatments

Authors: Huisi Ai, Scott Glaser, Yi Lao, Percy Lee, Sara N. Lim, An Liu, Bo Liu, Borna Maraghechi, Kun Qing, Chengyu Shi, William T. Watkins, Terence Williams, Qiuyun Xu, Jiahua Zhu

Affiliation: WashU Medicine, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, City of Hope Orange County, Department of Radiation Oncology, City of Hope National Medical Center, Department of Radiation Oncology, City of Hope Orange County, Department of Radiation Oncology, City of Hope Medical Center

Abstract Preview: Purpose: To employ a novel surface dose mapping approach for localized assessment of the dosimetric impact of Ethos adaptive radiotherapy (ART) for prostate cancer (PC).
Methods: This study include...

Empowering Radiation Oncology in Sudan with Virtual and Augmented Reality Solutions

Authors: Abdelfatah Abdalla Nemer Abdelsalam, Elmubarak M. Ahmed, Sarah A. Ashmeg, M. Saiful Huq, Alsadeg Awad Alamin Mohamed, Ali Sid Ahmed Mohammed, Christopher Tyerech

Affiliation: UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, UPMC Hillman Cancer Center, University of Medical Science and Technology, King Abdulaziz Medical City, Department of Radiation Oncology, University of Pennsylvania, Tumor Therapy and Cancer Research Center, Al Neelain University

Abstract Preview: Purpose: Severe conflict in Sudan has led to the closure of several cancer services within the country. With new centers in development by an IAEA and Rays of Hope initiative, many barriers exist in m...

Energy Dependency of Biological Effects from Radiation Scattering Around Medical Implants in Particle Therapy

Authors: John Ford, Yu Fujiwara, Isao Murata, Zavier Ndum Ndum

Affiliation: Osaka University, Texas A&M University

Abstract Preview: Purpose: This study investigates how particle energy affects radiation quality and biological effectiveness with the inclusion of medical implants. Our research group used microdosimetric analysis to ...

Enhancing Lung SBRT Planning Efficiency: A Template-Based Approach Using Chest Wall Overlapping Cases

Authors: Felicia Chu, Qiongge Li, Jian Liu

Affiliation: Inova Hospital, Brown University Rhode Island Hospital, Hofstra University Medical Physics Program

Abstract Preview: Purpose:
This study aims to enhance the efficiency of stereotactic body radiation therapy (SBRT) planning for lung cancer by developing and evaluating optimization templates derived from historical...

Enhancing Urethral Visualization for Prostate SBRT Using Post-Void T2-Weighted Imaging on a Low-Field 0.35T MR-Linac System

Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Nishan Shrestha, Somol Sunny

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: Accurate delineation of the urethra is critical for optimizing tumor control and minimizing urethral toxicity in prostate stereotactic body radiation therapy (SBRT). The purpose of this study...

Ensuring Consistency in Digital Pathology: Medical Physics Approaches to Comparison of Scanner Contrast and Chromaticity

Authors: Diana Cardona, Casey C. Heirman, William Jeck, Kyle J. Lafata, Xiang Li, Lauren M. Neldner, Jeffrey S. Nelson, Megan K. Russ, Ehsan Samei

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Pathology, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Medical physicists have traditionally supported radiation-based medicine, but their expertise can translate to other image-based fields including pathology. As pathology transitions to digita...

Ensuring Consistency in Digital Pathology: Medical Physics Approaches to Comparison of Scanner Sharpness and Artifact Severity

Authors: Diana Cardona, Casey C. Heirman, William Jeck, Kyle J. Lafata, Xiang Li, Lauren M. Neldner, Jeffrey S. Nelson, Megan K. Russ, Ehsan Samei

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Pathology, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Medical physicists traditionally support radiation-based medicine, but their expertise is translatable to image-based fields like pathology. As pathology transitions to digital practices, phy...

Estimating Organ Dose of Standard Pediatric CT Protocols to Computational Phantoms through the Dukesim CT Simulator

Authors: Dean Darnell, Iyanna M Lewis, Francesco Ria, William Paul Segars

Affiliation: Duke University, Duke University Medical Physics Graduate Program, Center for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Duke University Medical Center

Abstract Preview: Purpose: To estimate radiation dose to pediatric patients during standard CT imaging of the chest and abdomen and determine how dose varies with patient age, height and weight and how measurements com...

Evaluating Normal Tissue Toxicity Following Pulsed Low Dose Rate Radiotherapy

Authors: Shahabeddin mostafanazhad Aslmarand, Lili Chen, Dusica Cvetkovic, Troy A. Dos Santos, Chang Ming Charlie Ma, Dae-Myoung Yang

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose:
Pulsed low-dose-rate radiotherapy (PLDR) has been proposed to reduce normal tissue toxicity while maintaining tumor control comparable to conventional radiotherapy (CRT). This study assess...

Evaluating the Adequacy of Planning Target Volume Margins in Lung Stereotactic Body Radiation Therapy: Assessment of Intrafraction Motion Using a Fiducial Marker

Authors: Rashmi Benda, Qinghao Chen, Shifeng Chen, Giovanni Lasio, Peter Olivieri, Huijun Xu, Junliang Xu, Byong Yong Yi, Baoshe Zhang, Jinghao Zhou

Affiliation: University of Maryland Baltimore Washington Medical Group, Department of Radiation Oncology, University of Maryland School of Medicine, Capital Region Medical Center, University of Maryland Shore Regional Cancer Center

Abstract Preview: Purpose:
We investigated if the patients receiving lung stereotactic body radiation therapy (SBRT) have adequate planning target volume (PTV) margins by evaluating the intrafraction motion using a ...

Evaluating the Interchangeability of Two Similar but Not Beam-Matched Varian Truebeam Linear Accelerators in the Delivery of Patient-Specific Quality Assurance

Authors: Elizabeth M. Alves, Alistair K. Templeton, Julius V. Turian

Affiliation: Rush University Medical Center

Abstract Preview: Purpose: To test the performance of two similar, but not beam-matched, linacs in interchangeably delivering IMRT and VMAT patient-specific quality assurance (PSQA) tests.
Methods: Two TrueBeam lina...

Evaluating the Performance of Using Large Language Models to Automate Summarization of CT Simulation Orders in Radiation Oncology

Authors: Meiyun Cao, Edward L. Clouser, Xiaoning Ding, Jason Michael Holmes, Shaw Hu, Linda L. Lam, Wendy S. Lindholm, Wei Liu, Samir H. Patel, Diego Santos Toesca, Jason Sharp, Sujay A. Vora, Peilong Wang

Affiliation: Department of Radiation Oncology, Mayo Clinic, Mayo Clinic Arizona, George Washington University

Abstract Preview: Purpose: In current clinical workflow of radiation oncology departments, therapists manually summarize CT simulation orders into summaries before the CT simulation for execution. This process signific...

Evaluating the Role of Surface-Guided Radiotherapy in Prone Breast Cancer Treatment

Authors: Shifeng Chen, Mariana Guerrero, Michael J. MacFarlane, Huijun Xu, Baoshe Zhang, Jinghao Zhou

Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Capital Region Medical Center, University of Maryland Shore Regional Cancer Center

Abstract Preview: Purpose: The clinical value of surface-guided radiotherapy (SGRT) in prone breast cancer setups is much less established than in supine setups. This study explores SGRT's potential for prone breast pa...

Evaluation of Color Display Performance of Pathology Relevant Colors Using the Macbeth Colorchecker

Authors: Diana Cardona, Casey C. Heirman, William Jeck, Kyle J. Lafata, Lauren M. Neldner, Jeffrey S. Nelson, Megan K. Russ, Ehsan Samei

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Pathology, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Display image accuracy is critical for digital diagnostic fields, such as radiology and digital pathology. While the AAPM TG-18 test patterns are established for grayscale radiology monitor Q...

Evaluation of the Accumulated Dose in Combined Radiotherapy for Cervical Carcinoma Using DVH Addition and Deformable Image Registration Based on Optimization of BT Boost Region in EBRT

Authors: Qiu Tang, Yeqiang Tu, Jiahao Wang, Lu Wang

Affiliation: Women's Hospital School of Medicine Zhejiang University, Hangzhou Women's Hospital

Abstract Preview: Purpose: The BT boost regions were previously delineated and optimized during EBRT planning process. The differences of DVH parameters addition (PA), deformable dose summation (DS) with BT boost regio...

Evaluation of the Varian Truebeam Linac Matching Process: Before, during, and after the Commission

Authors: Edwin Quashie, Yun Wang

Affiliation: Indiana University Medical School, Indiana University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose: To provide a formal evaluation for the TrueBeam linac matching process before, during and after the commission of the newly installed TrueBeam linac which we want to match to an existing True...

Expanding the Reach: Integrating AI-Generated Auto Contours Via Ray Station’s Deep Learning Segmentation into Diverse Treatment Planning Systems

Authors: Raghavendra Raghavendra, Kanaparthy Raja Muralidhar, Venkataramanan Ramachandran, Srinivas Srinivas

Affiliation: Karkinos Healthcare

Abstract Preview: Purpose: This study explores the Integrating AI-Generated Auto Contours via Ray Station’s Deep Learning Segmentation into Diverse Treatment Planning Systems.
Methods: The research encompassed a gro...

Exploring NSCLC Microenvironments: Multi-Score Survival Models Integrationg Radiomics-Based Regional Imaging Features and Genomics

Authors: Nobuki Imano, Daisuke Kawahara, Misato Kishi, Yuji Murakami

Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University

Abstract Preview: Purpose: This study aims to develop a comprehensive Multi-score by integrating Radiomics-score (Rad-score), Gene-score derived from gene expression levels, and tumor environment Rad-score (TE-Rad-scor...

Feasibility Study of Group Sparse-Based Beam Angle Optimization for Multi-Field Carbon Ion Radiotherapy

Authors: Min Cheol Han, Hojin Kim, Jin Sung Kim, Hyejin Lee, Sac Lee, Yongdo Yun

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine

Abstract Preview: Purpose: Carbon ion radiotherapy (CIRT) is characterized by high relative biological effectiveness (RBE), which must be integrated into the treatment planning process. This study aims to develop a nov...

Feasibility of Developing a Radiomic Fingerprint to Predict Pulmonary Embolism Clot Types to Aid in Determining Intervention for Intermediate-Risk Patients.

Authors: Lindsay Hammons, Lisa Baumann Kreuziger, Haidy G. Nasief, Matthew Scheidt, Farrell Sean, Antonio Sosa Lozano

Affiliation: Division of Hematology and Oncology, University of Washington, Vascular and Interventional Radiology, Medical college of wisconsin, Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Venous thromboembolism, which includes pulmonary embolism (PE), is the third leading cause of acute cardiovascular syndrome behind myocardial infarction and stroke. Current research categoriz...

Feasibility of Rapidarc Dynamic for Lattice Radiation Therapy of Bulky Liver Tumors

Authors: Christine V. Chung, Laurence Edward Court, Meena S. Khan, Ethan B. Ludmir, Rachael M. Martin Paulpeter, Saurabh Shashikumar Nair, Callistus M. Nguyen, Joshua S. Niedzielski, Luis Augusto Perles

Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Spatially Fractionated Radiation Therapy (SFRT) has re-emerged as an efficacious treatment approach for bulky solid tumors. RapidArc Dynamic (RAD) has unique beam delivery capabilities that m...

Fetal Radiation Exposure Monitoring of Pregnant Employees across Multiple Departments and Areas in a Hospital

Authors: Janet Ching-Mei Feng, Janet Gutierrez, Aylin Ozus, Patricia Svolos

Affiliation: Bellaire High, McGovern Medical School, University of Texas Health Science Center at Houston, Environmental Health & Safety, University of Texas Health Science Center at Houston, UTHealth McGovern Medical School

Abstract Preview: Purpose: Exposure to radiation may become harmful to the fetus depending on the gestational age and absorbed dose. The Nuclear Regulatory Commission states the radiation exposure to the embryo/fetus o...

Flash Radiation Spares Reproductive Capability in Adult C. Elegans

Authors: Barry Andricks, Stratton Black, Scott R. Floyd, Ashutosh Kotwal, Eric L. Martin, Stepan Mikhailov, Mark Oldham, Niccolo Terrando, Andrew Thompson, Ying Wu

Affiliation: Department of Physics, Duke University, Medical Physics Graduate Program, Duke University, Duke University, Department of Radiation Oncology, Duke University Medical Center, Triangle Universities Nuclear Laboratory

Abstract Preview: Purpose: To evaluate and quantify the effects of high energy electron radiation delivered at FLASH and conventional dose rates on the reproductive capability of adult C. elegans nematodes.
Methods:...

Fractionation of Electron RT Reduces the Flash Effect in Murine Skin

Authors: Xu Cao, Wesley S. Culberson, Aleksandra Ilina, Kendall Jarvis, Brian W Pogue, Matthew Reed, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel

Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin–Madison, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison

Abstract Preview: Purpose: While FLASH radiotherapy is known to reduce skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR). Currently it is not clear whether this ...

Gene Interaction-Encoded Deep Learning Uncovers Microenvironment for Radiation-Induced Pulmonary Fibrosis

Authors: Md Tauhidul Islam, Junyan Liu, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose: Radiation-induced lung injury (RILI) is a common complication in patients receiving radiotherapy for lung cancer, with approximately 16%–28% developing pulmonary fibrosis. The exact mechanism...

Generalizable 7T T1 Map Synthesis from 1.5T and 3T T1W MRI for High-Resolution MRI-Guided Radiation Therapy

Authors: Zachary Buchwald, Chih-Wei Chang, Zach Eidex, Hui Mao, Richard L.J. Qiu, Justin R. Roper, Mojtaba Safari, Hui-Kuo Shu, Xiaofeng Yang, David Yu

Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Emory University School of Medicine

Abstract Preview: Purpose: MRI-guided radiation therapy (MRgRT) benefits significantly from enhanced soft-tissue contrast and spatial resolution, which aid in accurately delineating tumors and organs at risk. Although ...

Generalized Ontological Framework for CT Data Profiling and Characterization

Authors: Njood Alsaihati, Ehsan Samei, Justin B. Solomon

Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Inconsistent imaging procedure naming across and within institutions challenges clinical decision-making, quality assessment, and data analysis in radiology. For example, The American College...

Glandular Dose Map in Voxelized Phantoms across Advanced Breast Imaging Modalities Obtained from Monte Carlo Simulations

Authors: Rodrigo T Massera, Sofia Giaccone Thomaz, Alessandra Tomal, Giovanna Tramontin

Affiliation: Universidade Estadual de Campinas. Instituto de Física Gleb Wataghin, Department of Imaging & Pathology, unit of Medical Physics & Quality Assessment, KU Leuven

Abstract Preview: Purpose: Monte Carlo simulations are increasingly used in breast dosimetry for their precision in estimating difficult-to-measure quantities, such as glandular dose. With ionizing radiation in breast ...

Growing As Leaders Together – Results from the Medical Physics Leadership Academy Fundamentals of Leadership Cohort Program

Authors: Ashley Cetnar, Emily Y. Hirata, Cassandra Stambaugh

Affiliation: University of California San Francisco, Tufts Medical Center, The Ohio State University - James Cancer Hospital

Abstract Preview: Purpose: To provide results from the first four years of the Medical Physics Leadership Academy (MPLA) Fundamental of Leadership Cohort program
Methods: The MPLA Cohorts program began with the Fund...

Hyperbaric Oxygen Therapy Prior to SRS Does Not Enhance Radiosensitivity in the Murine Glioblastoma Model

Authors: Beverly Allen, Jay C. Buckey, David J. Gladstone, P. Jack Hoopes, David I Hunter, Armin Tavakkoli

Affiliation: Thayer School of Engineering, Dartmouth College, Geisel School of Medicine, Dartmouth College, Geisel School of Medicine, Thayer School of Engineering

Abstract Preview: Purpose: Hyperbaric oxygen (HBO) therapy immediately prior to radiation therapy has been proposed as treatment to enhance radiosensitivity of hypoxic tumors. A murine glioblastoma model was utilized t...

Icrp Mesh-Type Reference Computational Phantoms Representing Pregnant Women and Fetuses

Authors: Wesley E. Bolch, Chansoo Choi, Chan Hyeong Kim, Suhyeon Kim, Bangho Shin, Yeon Soo Yeom

Affiliation: Hanyang University, University of Florida, 2) Department of Radiation Convergence Engineering, Yonsei University

Abstract Preview: Purpose: Task Group 103 of International Commission on Radiological Protection (ICRP) recently released new-generation adult and pediatric mesh-type reference computational phantoms (MRCPs) via ICRP P...

Immune Response on Ultra-High Dose Rate (FLASH) and Conventional Proton Radiation in a Mouse Xenograft Model

Authors: Ning Cao, Sunan Cui, Danielle P. Johnson Erickson, Juergen Meyer, Ramesh Rengan, Ben A Shaver, Jing Zeng

Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington and Fred Hutchinson Cancer Center, University of Washington

Abstract Preview: Purpose: To investigate the immune response in primary irradiated tumors and non-irradiated tumors in a mouse melanoma xenograft model, comparing 18Gy of conventional (CONV) and ultra-high dose rate (...

Impact of Positron Emission Tomography (PET) Image Characteristics on Biology-Guided Radiotherapy (BgRT) Treatment Accuracy

Authors: Angela J Da Silva, Andrew Groll, Manoj Narayanan, Jeffrey Schmall, Sanchit Sharma, Timothy Pok Chi Yeung

Affiliation: Reflexion Medical Inc,, RefleXion Medical

Abstract Preview: Purpose: PET-based biology-guided radiotherapy (BgRT) is a radiation therapy technique that uses PET imaging to deliver tracked dose to the tumor in real-time. We characterized the delivery accuracy o...

Impact of Transfer Learning on Estimation of Intravoxel Incoherent Motion Parameters in the Liver

Authors: Marissa Brown, Geoffrey D. Clarke, Luke Norton

Affiliation: University of Texas Health Science Center at San Antonio

Abstract Preview: Purpose: To evaluate how different learning strategies affect convolutional neural network (CNN) estimates of the liver's intravoxel incoherent motion (IVIM) parameters.
Methods: A 3-stage U-Net wa...

Impact of Tumor-to-Normal Ratio and Glass Microsphere Particle Density on Local Progression-Free Survival Following Lobar Yttrium-90 Radioembolization

Authors: Jason Chiang, Magnus Dahlbom, Veronica Hankil, Xinyi Li, Catherine (Caffi) Meyer, Kyung Hyun Sung

Affiliation: UCLA, University of California, Los Angeles

Abstract Preview: Purpose:
Yttrium-90 (90Y) radioembolization is a well-established therapy for large or multifocal liver tumors. Accurate dosimetry is critical but remains challenging, as low particle density risks...

Impact of a Dedicated Working Group on Standardization of CT-Guided Adaptive Radiation Therapy

Authors: Anthony J. Doemer, Aharon Feldman, Ian Gallagher, Yimei Huang, Brett M. Miller, Benjamin Movsas, Kundan S Thind

Affiliation: Henry Ford Health

Abstract Preview: Purpose: CT-guided adaptive radiation therapy (CTgART) is a technical, resource intensive, procedure that involves many different radiation oncology team members. To ensure consistent, high-quality CT...

Implementing Equity, Diversity, and Inclusion in Medical Physics Education: The Role of AI-Powered Chatbots

Authors: James Chun Lam Chow, Kay Li

Affiliation: University of Toronto, Princess Margaret Cancer Centre

Abstract Preview: Purpose: This study aims to integrate Equity, Diversity, and Inclusion (EDI) principles into AI-driven educational tools for medical physics. The goal is to create a chatbot framework that fosters acc...

Improved Setup Accuracy for Dibh Whole Breast Radiotherapy with Surface-Guided Radiation Therapy

Authors: CheukKai Becket Hui, Goldie M. Klein, Yildirim D. Mutaf, Amir Pourmoghaddas

Affiliation: UC Health, Kaiser Permanente

Abstract Preview: Purpose:
In this study, we investigated the effect of SGRT (Align-RT) implementation on patient setup accuracy for DIBH breast radiotherapy treatments.
Methods:
We extracted vertical post-ima...

Improvement of Spine Phantom for MR Imaging of the Spine

Authors: Richard Dortch, Thammathida Ketsiri, Zhiqiang Li, Shiv P. Srivastava

Affiliation: Barrow Neurological Institute, Dignity Health Cancer Institute, St. Joseph's Hospital & Medical Center

Abstract Preview: Purpose: Imaging the spinal cord post-surgery is challenging due to metal surgical implants, which induce signal loss and geometric distortions. Together, this hinders the visualization of the spinal ...

In Vivo Dosimetry for Cied Management – Is It Really Needed?

Authors: Anthony J. Doemer, Aharon Feldman, Stephen J. Gardner, Brett M. Miller, Benjamin Movsas, Farzan Siddiqui, Chadd Smith, Kundan S Thind, Kyle Verdecchia

Affiliation: Henry Ford Health

Abstract Preview: Purpose: To evaluate the efficacy of calculation-only approach for CIED risk-level assessment.
Methods: A total of 86 patients were included in this retrospective analysis. For each patient, in viv...

Incorporating Cyclic Group Equivariance into Deep Learning for Reliable Reconstruction of Rotationally Symmetric Tomography Systems

Authors: Fang-Fang Yin, Lei Zhang, Yaogong Zhang

Affiliation: Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Rotational symmetry is an inherent property of many tomography systems (e.g., CT, PET, SPECT), arising from the circular arrangement or rotation of detectors. This study revisits the image re...

Induced Bystander Effect in MCF-7 Breast Cancer Cells after X-Ray Irradiation

Authors: Beatriz Allyne Dia Carandang, Chitho P Feliciano, Teresa Sy-Ortin

Affiliation: Department of Physical Sciences and Mathematics, University of the Philippines Manila, Health Physics Research Section, Atomic Research Division, Department of Science and Technology-Philippine Nuclear Research Institute (DOST-PNRI), Graduate School, University of Santo Tomas

Abstract Preview: Purpose: To investigate the X-ray radiation-induced bystander effect (RIBE), where unirradiated cells mimic the responses of directly irradiated cells, in MCF-7 breast cancer cells in vitro to underst...

Integrated Catheter Position and Dwell Time Optimization for Focal Dose Escalation in Prostate HDR Brachytherapy

Authors: Bryan Bednarz, John M. Floberg, Joseph B. Schulz, Jordan M. Slagowski

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Catheter placement for high-dose-rate brachytherapy (HDR BT) is clinician dependent and potentially suboptimal for delivering simultaneous integrated boosts to intraprostatic gross tumor volu...

Integrating Foundation Model with Self-Supervised Learning for Brain Lesion Segmentation with Multimodal and Diverse MRI Datasets

Authors: Zong Fan, Fan Lam, Hua Li, Rita Huan-Ting Peng, Yuan Yang

Affiliation: University of Illinois at Urbana Champaign, University of Illinois at Urbana-Champaign, Washington University School of Medicine, University of Illinois Urbana-Champaign

Abstract Preview: Purpose: Accurate lesion segmentation in MRI is critical for early diagnosis, treatment planning, and monitoring disease progression in various neurological disorders. Cross-site MRI data can alleviat...

Investigating CT-Based Lung Ventilation Heterogeneity As a Biomarker for COPD Severity

Authors: Shiho Amster, Ryan Andosca, Igor Barjaktarevic, Michael Vincent Lauria, Daniel A. Low, Dylan P. O'Connell, Ann Raldow, Brad Stiehl

Affiliation: Department of Pulmonology, University of California Los Angeles, Department of Radiation Oncology, University of California, Los Angeles, Cedars-Sinai Medical Center

Abstract Preview: Purpose: Image-based biomarkers could be useful for disease diagnosis and prognosis, especially in heterogeneous lung diseases like COPD. The purpose of this study is to assess the feasibility of usin...

Investigating Racial Differences in 68ga-PSMA-11 PET/CT Imaging for Patients with Biochemical Recurrence after Radical Prostatectomy: Preliminary Findings

Authors: Maya Ataya, Clint Bahler, Ramotallah Dami Jubril, Michael Koch, Oluwaseyi Oderinde, Mark Tann

Affiliation: Purdue University, epartment of Urology, Indiana University School of Medicine, Department of Urology, Indiana University School of Medicine, Department of Radiology and Imaging Sciences, Indiana University School of Medicine

Abstract Preview: Purpose:
To investigate racial differences in the detection of biochemical recurrence (BCR) using 68Ga-PSMA-11 PET/CT, known for its improved sensitivity and specificity in patients after radical p...

Investigating in-Vivo Megavoltage Radiodynamic Therapy from 6 to 45MV Photon Beam Radiation Therapy with 5-Aminolevulinic Acid

Authors: Lili Chen, Dusica Cvetkovic, Chang Ming Charlie Ma, Dae-Myoung Yang

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose: 5-aminolevulinic acid (5-ALA)-mediated radiodynamic therapy (RDT) has been shown to be an effective treatment option using high-energy photon beams. RDT utilizes tumoricidal capabilities caus...

Investigating the Flash Effect: Uncovering Brain Sparing and Cognitive Preservation across Varying Dose Rates in Whole-Brain Irradiation of in-Vivo Mouse Models

Authors: Denise Dunn, Scott R. Floyd, Tyler V. Kay, Anna Lynnette-Price, Eric L. Martin, Stepan Mikhailov, Taylor Nguyen, Mark Oldham, Victoria J. P. Radosova, Zachary J. Reitman, Ramona Rodriguiz, Andrew Thompson, William Wetsel, Seth Wilcox, Ying Wu

Affiliation: Duke University Mouse Behavior Core, Department of Physics, Duke University, Medical Physics Graduate Program, Duke University, Duke University Medical Physics Program, Duke University, Duke University Mouse Behavioral and Neuroendocrine Analysis Core Facility, Department of Radiation Oncology, Duke University Medical Center

Abstract Preview: Purpose: FLASH radiation therapy (RT) shows promise for reducing normal tissue damage, though its mechanisms remain unclear. Using an in-vivo model with the High Intensity Gamma-ray Source (HIGS) lina...

Investigation of High Cumulative Doses and Dose Outliers in a Pediatric Hospital

Authors: Niki Fitousi, Stanley Thomas Fricke, Anna Romanyukha

Affiliation: Qaelum NV, Children's National Hospital

Abstract Preview: Purpose:
To identify opportunities for improvement through investigation of outliers in exam dose length product (DLP) and patients receiving high cumulative doses (CED), in the context of our “ped...

Investigation of Triggered Imaging and Auto Beam Hold Using a Dynamic Thorax Phantom for Intra-Fraction Motion Management

Authors: Liu Hong, Zhong Su

Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)

Abstract Preview: Purpose: During treatment delivery on TrueBeam platform 2.7, Triggered Imaging (TI) enables kV images acquisition at regular intervals and Auto Beam Hold (ABH) provides beam pausing if the target is m...

LD-V1 Film Characterization for MV Beam Quality

Authors: Ruiming Chen Edmondson, Darwin Abraham Garcia, James A. Kavanaugh, Joseph John Lucido

Affiliation: Mayo Clinic

Abstract Preview: Purpose: Characterize the dose response and reproducibility of a low-dose film for 6 MV photon beam and assess the film’s energy dependence between kV and MV energies.
Methods: A single 8’x10’ LD-V...

LLM-Enhanced Multi-Modal Framework for Predicting Pain Relief of Stereotactic Body Radiotherapy for Spine Metastases Using Clinical Factors and Imaging Reports

Authors: John Byun, Steven D Chang, Mingli Chen, Cynthia Chuang, Xuejun Gu, Melanie Hayden Gephart, Yusuke Hori, Hao Jiang, Mahdieh Kazemimoghadam, Fred Lam, Gordon Li, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang, Qingying Wang, Zi Yang, Xianghua Ye, Kangning Zhang

Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Accurate prediction of pain relief is crucial in determining the clinical effectiveness of Stereotactic body radiotherapy (SBRT) regimen for spine metastases. We propose a deep-learning frame...

Large Scale Deployment of a Tailored and Hybrid Educational Strategy for Wartime Capacity Building: Aapm/HUG/Uamp Initiative to Transition Ukraine from Co-60 to IMRT through a Comprehensive Medical Physics Training Program

Authors: Victoria Susan Ainsworth, Stephen M. Avery, Serhii Brovchuk, Thomas Brown, Sean A. Dresser, Matthew D. Goss, Viktor M. Iakovenko, Kelly Kisling, Nataliya Kovalchuk, Robert F. Krauss, Wilfred F. Ngwa, Jatinder R. Palta, Julie A. Raffi, Peter Allan Sandwall, Natalka Suchowerska, William Swanson, Shada J. Wadi-Ramahi, Ruslan Zelinskyi

Affiliation: Allegheny Hospital, Johns Hopkins University, Virginia Commonwealth University, Stanford University, O.O. Shalimov National Institute of Surgery and Transplantology, Department of Radiation Oncology, UT Southwestern Medical Center, School of Physics, The University of Sydney, MaineHealth, University of California, San Diego, Duke University, Emory University, University of Pennsylvania, University of Pittsburgh Medical Center, Medical Physics Department, Medical center of Yuriy Spizhenko, OhioHealth, University of Massachusetts Lowell, St. Francis Hospital

Abstract Preview: Purpose: The AAPM International Council, in collaboration with Help Ukraine Group (HUG) and Ukrainian Association of Medical Physicists (UAMP), developed a novel hybrid year-long training course to as...

Latent Diffusion for 3D CT Reconstruction from Biplanar X-Rays

Authors: Guha Balakrishnan, Osama R. Mawlawi, Yiran Sun, Ashok Veeraraghavan

Affiliation: RICE University, UT MD Anderson Cancer Center

Abstract Preview: Purpose:
Previous deep learning (DL) techniques such as X2CT-GAN [1] has shown great promise in reconstructing realistic CT volume from biplanar X-rays, however they introduce numerous artifacts in...

Longitudinal CMR Strain Analysis of Right Ventricular (RV) Function across Aging in Offspring of Baboons Exposed to Moderate Maternal Undernutrition

Authors: Geoffrey D. Clarke, Laura A. Cox, Alexander J Moody, Peter W Nathanielsz, Bowen Yang

Affiliation: Wake Forest University School of Medicine, University of Texas Health Science Center at San Antonio, Texas Biomedical Research Institute

Abstract Preview: Purpose:
Recent studies show diagnostic value of myocardial strain analysis for left ventricular (LV) function using cardiac magnetic resonance imaging (CMR). RV function analysis is more challengi...

Lymphocytic Feature Characterization Using a Deep Learning Algorithm on Post-Radiation Lymph Nodes

Authors: Rico Castillo, Katherine Gonzalez, Casey C. Heirman, Kyle J. Lafata, Casey Y. Lee, Xiang Li, Yvonne M Mowery, Yvonne M Mowery, Daniel Murphy, Allison Pittman, Ashlyn G. Rickard

Affiliation: Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh

Abstract Preview: Purpose: To evaluate the ability of a deep learning model to identify pathomic features in lymph nodes of preclinical head and neck squamous cell carcinoma (HNSCC) models as surrogates for predicting ...

Mesial Temporal Tau-PET Is Related to Diffusion Tensor Imaging Outcomes in Adults with Down Syndrome

Authors: Andrew Alexander, Brecca Bettcher, Bradley T Christian, Jose Guerrero-Gonzalez, Steven Kecskemeti, Lisette LeMerise, Max McLachlan, Andrew McVea, Matthew Zammit

Affiliation: University of Wisconsin-Madison School of Medicine and Public Health and Waisman Center

Abstract Preview: Purpose: Individuals with Down syndrome (DS) develop Alzheimer’s Disease (AD) with very high prevalence (>90%). Neuropathology includes amyloid plaque (Aβ) accumulation, followed by neurofibrillary ta...

Minimizing Abscopal Effects in Normal Tissues with Flash-RT: Mechanisms of Action and Potential Clinical Applications

Authors: Liang Cui, Xingyu Lu, Hang Shang, LingHong Zhou

Affiliation: Southern Medical University

Abstract Preview: Purpose: This study examines how varying dose rates of radiotherapy impact normal tissues outside the target area and analyzes the protective effects and regulatory mechanisms of ultra-high dose rate ...

Modality-Agnostic Image Cascade (MAGIC) for Multi-Modality Cardiac Substructure Segmentation

Authors: Ming Dong, Carri K. Glide-Hurst, Qisheng He, Anudeep Kumar, Alex Singleton Kuo, Joshua Pan, Chase Ruff, Nicholas R. Summerfield

Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Recent evidence highlights the importance of incorporating cardiac substructures (CS) into treatment planning for thoracic cancers, however current segmentation methods are limited to a singl...

Multi-Modality Artificial Intelligence for Involved-Site Radiation Therapy: Clinical Target Volume Delineation in High-Risk Pediatric Hodgkin Lymphoma

Authors: Tyler J Bradshaw, Sharon M Castellino, Steve Y Cho, David Hodgson, Bradford S Hoppe, Kara M Kelly, Andrea Lo, Sarah Milgrom, Xin Tie

Affiliation: Department of Radiation Oncology, University of Toronto, Department of Radiology, University of Wisconsin, University of Colorado Anschutz, Department of Medical Physics, University of Wisconsin, Department of Radiation Oncology, Mayo Clinic, Department of Radiation Oncology, BC Cancer, Vancouver Center, Department of Radiology, University of Wisconsin - Madison, Roswell Park Comprehensive Cancer Center, Emory University School of Medicine

Abstract Preview: Purpose: Clinical target volume (CTV) delineation for involved-site radiation therapy (ISRT) in Hodgkin lymphoma (HL) is time-consuming due to the need to analyze multi-time-point PET/CT scans co-regi...

Multi-Sid Optimization for 4 Pi Robotic Radiotherapy

Authors: Qihui Lyu, Dan Ruan, Ke Sheng, Jingjie Yu

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose: The robotic arm radiotherapy platform enables flexible delivery of non-coplanar and non-isocentric radiotherapy with variable Source-to-Isocenter Distances (SIDs). However, the high degrees o...

Multicentric Characterization of Organ-Based Tube Current Modulation in Thoracic and Abdominopelvic Computed Tomography: A Dosimetric and Image Quality Study

Authors: Corentin Desport, Dominique Iacchetti, Nicolas Kien, Ramiro Moreno, Melodie Munier, Séléna Pondard

Affiliation: Fibermetrix, Alara Expertise, Alara Group

Abstract Preview: Purpose: To evaluate the efficiency of organ-based tube current modulation (OBTCM) in thoracic and abdominopelvic Computed Tomography (CT) for different radiology departments and manufacturers. This s...

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Authors: Houssam Abou Mourad, Christopher Ackerman, Stephen Adler, Kirk Aduddell, Muhammad K. Afghan, Hamid G. Aghdam, Diego Aguilar, Kang-Hyun Ahn, Francis Ai, Hua Ai, Ray Anthony Aikens, Manik Aima, Victoria Ainsworth, Erfan Akbari, Blessing Akinro, Rani Al-Senan, Khalid Alabbasi, Sam Alam, Daniel Alexander, Mohammed H. Aljallad, Mazin T. Alkhafaji, Ahmad K. Alkhatib, Scott J. Alleman, James Logan Allen, Ibtisam Almajnooni, Tiba Alnaqshabandi, Murat Alp, Stephen J. Amadon, Riska Amilia, Ala Amini, Shiho Amster, Mason R. Anders, Erin Angel, Ledi Anggara, John A. Antolak, Debora Antonio, Felicity Appiah, Haiqa Arain, Lahcen Arhjoul, Ali V. Aritkan, Muhammad Arshad, Mark E. Artz, Nathan S. Artz, Frank A Ascoli, John R. Ashburn, Benjamin Astarita, Masakazu Atsumi, Rex G. Ayers, Tara M. Bachman, Nina L. Bahar, Bing Bai, Michael J. Bailey, Chris Baird, Mohammad Bakhtiari, Andrew J. Ballesio, Isabel Balvoa, Qinan Bao, Jeffrey J. Barbarits, Joseph Barbiere, Philip C. Bardos, Gary T. Barnes, John C. Barrett, Divya Bartley, Steven J. Bartolac, Robert Barton, Christopher P. Bass, Loni Bates, Alan Baydush, John E. Bayouth, Stephen Beach, Kevin Beaudette, Kaelyn Becker, Natalie A. Beckmann, Colleen Beer, Sepideh Behinaein, Jake M. Bell, David M. Bellezza, Maria R. Bellon, Ahmed Benelfassi, Stephanie Louise Bennett, Todd Bernath, Kate Bevins, Nicholas B. Bevins, Brian J. Bismack, David Blaich, Anthony P. Blatnica, Joseph W. Blickenstaff, Steven Blum, Maggie Bobbett, Dayna Bodensteiner, Daniel Boedeker, Robert C. Boggs, Jason D. Bond, Sjirk N. Boon, Jennifer M. Borsavage, Ryan J. Bosca-Harasim, Ryan J. Bosca-Harasim, Satya R. Bose, Todd Bossenberger, Cristina Boswell, Djamal Boukerroui, Christopher M. Bowen, Aaron Brammer, Rich Brancaleoone, Eric Brass, Luis Bravo, William Breeden, Christina Breeze, Eric E. Brost, Justin L. Brown, Karen L. Brown, Marissa Brown, Norman Lee Brown, Payton Brown, Patrick V. Brunick, Ryan Brunkhorst, Gwendolyn P. Brunner, Camelia E. Bunaciu, Maria Bunta, Olwen Burton, Karim Butalag, Priscilla F. Butler, Angela Cagwin, Jeffrey L. Campbell, Warren G. Campbell, Tyler Cantrell, Xu Cao, Yanan Cao, Peter F. Caracappa, Amanda M. Caringi, Joe Caron, Joshua Carter, Kenneth W. Cashon, Sarah Castillo, Everett Cavanaugh, Suran Chae, Abhi Chakrabarti, PhD, Philip Chan, Jina Chang, Sha X. Chang, Youssef M. Charara, Pierre E. Charpentier, Priyanka Chaudhary, Senthamil Selvan Chelliah, Chen Chen, Doris Chen, Kuan Ling Chen, Max Chen, Mingyue Chen, Mu Chen, Xinan Chen, Yie Chen, Yong Chen, Caroline Cheney, Shyh-Shi R. Chern, Stephen Thomas Chesser, Kin Man Cheung, Pai-Chun Melinda Chi, Yuwei Chi, Omar Chibani, Hung Ching, Gwi Ae Cho, Jongmin Cho, David Choi, Wing Yan Choi, Nitish Chopra, Daniel Christ, Olav I. Christianson, Emmanuel Christodoulou, Heeteak Chung, Sophia Claudio, Arely Clavel, William J. Clouse, Gilad Cohen, Michael S. Cohen, Vladimir Collantes, Jason Collier, Jacob Collins, Daria C. Comsa, Charles Conduah, Virgil N. Cooper, Anita M. Corrao, Frank D. Corwin, Mihaela Cosma, Ben Coull-Neveu, Mary K. Cox, Daniel F. Craft, Steven D. Crawford, Troy M. Crawford, Charles E. Creagh, Beatrice Croteau, Camille Crumbley, Wilbert F. Cruz, Guoqiang Cui, J. Adam M. Cunha, Scott Cupp, Bruce H. Curran, Jordan McCauley Cutsinger, Alita D Almeida, Harold DSouza, Nana Dabo-Akoteng, Robert Dahl, Shaun W. Dahl, Ghayath Dakkouri, Malek Daneshvarnezhad, Mylinh Dang, Matt Daniels, George M. Daskalov, David A. Davenport, Amanda Davidek, Scott E. Davidson, Maria De Ornelas, Dylan A. DeAngelis, Mike Deady, Daniel Dean, Savannah Decker, Savannah Decker, Michael Delafuente, Omer Demirkaya, Logan Dempsey, Marc Dennis, Viv Dennis, Dana Derby, Garron A. Deshazer, Veronique Destombes, Ajaya K. Devabhaktuni, Suneetha Devpura, James A. Deye, Shalmali Dharmadhikari, Dominic J. DiCostanzo, Richard V. DiPietro, Emily Diller, Lei Ding, Nayha V. Dixit, Charles Dodge, David N. Dodoo Amoo, Shana Donchatz, Lei Dong, Elangovan Doraisamy, Jennifer E. Dorand, Sarah Driver, Jiayi Du, Michael Duax, Ibrahim M. Duhaini, Ibrahim Duhaini, Kristen Duke, Richard Dunia, Leon Dunn, Shannon R. Durfee, Brittany Earl, Behzad Ebrahimi, Colton Eckert, Hisham Elasmar, John G. Eley, Abdelhamid Elfaham, David C. Ellerbusch, Scott J. Emerson, Sara Endo, David Erickson, Freddy Escorcia, Caroline Esposito, Patrice Essien, Adam Evearitt, Benjamin Fahimian, Liliosa C. Fajardo, Kevin Fallon, Guoqing Fan, Jiahua Fan, Mingdong Fan, Pei Fan, Bing Fang, Jian Fang, Yile Fang, Marc A. Felice, Ye Feng, Michele Sutton Ferenci, Philippe Feru, Jade Alecia Fischer, Aaron Fishbein, Caitlyn M. Fitzherbert, Damian Fondevila, Grant Fong, Robert Wesley Foster, Luke Fourie, Jeffrey Brian Fowlkes, Alexandre Franca Velo, D. Jay Freedman, Ronald W. Frick, Jie Fu, Samuel Fulton, Kamalakar Gaddam, Justin D. Gagneur, Mariana Gallo, Mariana Gallo, David Gammel, Robert G. Gandy, Junfang Gao, Yiming Gao, Victor L. Garcia, Michael Garcia-Alcoser, Jeffrey Garrett, Steven Anthony Gasiecki, Keith Gatermann, Avinash Gautam, Bhoj Gautam, Olivier Gayou, Andrew J. Gearhart, Paul B. Geis, Renil B. George, David P. Gierga, Robert Gilliam, James Giltz, Eric L. Gingold, Frederic Girard, Garth Gladfelder, Sharon Glaze, Brendan K. Glennon, Steven P. Glennon, Guy Godwin, David Lloyd Goff, Lisa M. Goggin, Daniel Goldberg-Zimring, Edward Joseph Goldschmidt, Ehsan Golkar, Angel Gomez, Jason Gong, Manish K. Goyal, Frank Graeff, Royce L. Gragg, Jonathan Gray, Alexander D. Green, Olga L. Green, Andrew Christopher Greene, Travis Greene, Jared Grice, Kevin T. Grizzard, Suveena Guglani, Jeffrey B. Guild, Patrick P. Guo, Sandesh Gupta, Megan Gute, Jonathan Ha, Rachael L. Hachadorian, Christopher Haddad, Lubomir Hadjiiski, Scott W. Hadley, Tomoe Hagio, Kelsey Hall, Logan P. Hall, Klaus A. Hamacher, Amineh Hamad Khatib, Amineh O. Hamad Khatib, Brian R. Hames, Carnell Hampton, Samuel S. Hancock, Robyn S. Handschuh, Jeremy Hansen, Paul Harden, Joseph Harms, Daniel P. Harrington, Carley Harris, Jamie Marie Harris, Jennifer Hart, Richard P. Harvey, Jeremy Hawk, Naoki Hayashi, Maria Laura Haye, Katherine Hazelwood, David Hearshen, Bret H. Heintz, Adam Henry, Frank William Hensley, Michael Chris Hermansen, Marissa Hernandez, Nadia Hernandez, Dayadna Hernandez Perez, Sarah Hetherington, Emily Hewson, Maynard High, Brian P. Hill, Charles B. Hill, Yunsil Ho, Simeon Hodges, David M. Hoeprich, Michael N. Hoff, Robert F. Hoffman, Russell Holden, Clay Holdsworth, Scott Hollingsworth, John R. Holmes, Steve Holmes, Neal S. Holter, Thomas M. Holtschneider, Amirul Hoque, Sabbir Hossain, Tyler S. Howlin, Andrew Robert Hoy, An Ting Hsia, Hao-Yun Hsu, David Hu, Tom C. Hu, Yu-Chi Hu, Long Huang, Mi Huang, Joshua Hubbell, Michael J. Huberts, Julie C. Hudson, Geoffrey Hugo, Donglai Huo, Justin D. Hurley, Martina H. Hurwitz, Mohammad NASEEM Hussain, Andrew Hwang, Ui-Jung Hwang, Joe Ianni, Geoffrey Ibbott, Khalil Ibrahim, Ileana Iftimia, Mohammad Islam, Oleksandra Ivashchenko, Keyvan Jabbari, Joshua Jackson, Joshua Jackson, Ferenc Jacso, Mary Ellen Jafari, Karim Jaffer, Amit Jain, Ngoneh Jallow, Sachin R. Jambawalikar, Joshua A. James, Sunyoung Jang, Desiree Jangha, Tomaj Javidtash, Jun-Hsuang Jen, Peter Jenkins, Todd P. Jenkins, Andrew R. Jensen, Mads Lykke Jensen, Hosang Jin, Bowen Jing, Danielle Marie Johnson, Joshua D. Johnson, Holly Johnston, Kevin Jones, Badal R. Juneja, Nikhil Sriram Kabilan, Robert Kaderka, Jaclyn Kain, Faraz Kalantari, Maduka M. Kaluarachchi, Ali Kamen, Amrit Kaphle, Alireza Kassaee, Saravjeet Kaur, Vaiva Kaveckyte, Linda A. Kelley, Katelyn Kelly, Kathryn Elise Bales Kelly, Delsin B. Khan, Om Khanal, Maksud Khatri, William Steadman Kiger, Bryan Kim, Jong Oh Kim, Sangroh Kim, Sophia Kim, Brian W. King, Erica Kinsey, Assen S. Kirov, Marc T. Kleiman, Matic Knap, Robert J. Kobistek, Inger-Karine Kolkman-Deurloo, Erika Kathryn Kollitz, Dramane Konate, Xiang Kong, Walter Kopecky, Sandra Kos, Nataliya Kovalchuk, Shane Krafft, James A. Kraus, Robert Krauss, Deae-eddine Krim, Serguei Kriminski, Kerry T. Krugh, Lichung Ku, Esra Kucukmokroc, Randi Kudner, Andrew T. Kuhls-Gilcrist, Antti Juhani Kulmala, Akila D. Kumarasiri, Zacariah E. Labby, Taylor Lackey, Edcer Jerecho Laguda, Thang Lam, Michael A. S. Lamba, Kara Lambson, Laurel Zenaida Larramendi, Andy D. Lau, Wolfram Laub, Tyler Laugh, Robert P. Laureckas, Donald Laury, Patricia Lavey, Ashlie Laydon, Adam LeVay, Brandon Lee, Brian Lee, Dong-Chang Lee, Ji Hyun Lee, Jui-Min Lee, Bryan Lemieux, Matthew Lesher, Nicole Leslie, Etienne Lessard, Trish Lewis, Alan Li, Alexander N. Li, Hui Li, Jenny Li, Jiaxin Li, Qiongge Li, Taoran Li, Xiang Li, Yanlong Li, Zisheng Li, Xing Liang, Yun Liang, Chien-Yi Liao, Karisa Liaw, Sung-Yen Lin, Tiffany Lin, Holly M. Lincoln, Lin Ling, Chang Liu, Shaohua Liu, Yu Liu, Chih-Ming Mark Lo, Eric Lobb, Dilson Lobo, Virginia L. Lockamy, Lauren C. Long, Nelia S. Long, Troy Long, Michele Loscocco, Thomas Lowinger, Cynthia Lu, Minghui Lu, Winnie Lu, Yonggang Lu, Jianqiao Luo, Pei-Chin Luo, Xuhan Luo, Jan Luse, Daniel A. Lutterman, Dang Hoang Oanh Luu, Yulia Lyatskaya, Trina Lynd, Morgan Cervo Lyon, Chi Ma, Jingfei Ma, Tianjun Ma, Laurie Madden, Gregory E. Madison, Kurt Maffei, Michael J. Maffett, Nyasha G. Maforo, Dennise Magill, Emma Magness, Alphonso W. Magri, Dennis Mah, Usman Mahmood, Rebecca N. Mahon, Courage Mahuvava, Andrew D. Maidment, Gerassimos M. Makrigiorgos, Harish K. Malhotra, Kate Mallory, P. Scott Mange, Vivek Maradia, Jacob Marasco, Camilla Marino, Loren R. Marous, Wagner Marques, Craig M. Marsden, Edward I. Marshall, Jonathan Marshall, Caroline Martel, Colin Martin, Alejandro Martinez, Jeffrey P. Masten, Richard Mathew, Bobby Mathews, Anetia S. Matthews Jackson, Matthew R. Maynard, Joel R. McAllister, Rafe McBeth, James A. McCulloch, Kiernan T. McCullough, Keelin McGee, Kiaran P. McGee, Brian M. McGill, Christopher M. McGuinness, Robert McKoy, Steven M. McQuiggan, Lacey Medlock, Chirag D. Mehta, Nancy Meiler, Robert Meiler, Matthew A. Meineke, Caroline Melancon, Daniel S. Meleason, Carolyn Meltzer, Chunhua Men, Stephanie Merkl, Michael Merrick, Keith A. Michel, Georgeta Mihai, Ana Mihail, Devin A. Miles, Edward J. Miller, Elizabeth A. Miller, Ronaldo Minniti, Linda Minor, Filmon Misgina, Ajeet Kumar Mishra, Chad Mitchell, Drew P. Mitchell, Gregory S. Mitchell, Jessica Mitchell, Jacqueline Moga, Uwe Mollenhauer, Julien-Fabrice Ngoune Momo, Emi Mondragon, Nicholas Mongillo, Victor J. Montemayor, Scott Montgomery, Diego Luis Montufar Hidalgo, Mohammadamin Moradi, Serban Morcovescu, Jill Anna Moreau, Terrance Moretti, Toby Morris, Courtney K. Morrison, Alexander Albert Morrow, Jill Moton, Jonathon Mueller, Reshma Munbodh, Daniel W. Mundy, Daniela Murgulet, Scott A. Murphy, Benjamin C. Musall, Jana E. Musgrove, Samantha Musial, Yong Hum Na, Joel Nace, Paul Naine, Justin Napolitano, Vrinda Narayana, Ganesh Narayanasamy, Moulay Ali Nassiri, Muhammad Naveed, Richard D. Nawfel, Ritish Nedunoori, Aaron Nelson, Kristin J. Nelson, Aaron Nelson, MD, Neerajan Nepal, Emily Neubauer Sugar, Shree Neupane, David Newey, Mark Newpower, Susan Ng, Bau H. Nguyen, Daniel J. Nicewonger, Xingyu Nie, Ethan Nikolau, Kevin D. Nitzling, Kai Niu, John M. Noll, Prashanth K. Nookala, Khalid Noori, James T. Norweck, Hamidreza Nourzadeh, Jessica L. Nute, Sebastiaan Nysten, Kevin OGrady, Ceferino Obcemea, Keith Ober, Jacqueline Ogburn, Timilehin Ogunbeku, Mina Okello, Brian Olson, Martin Keane Ongeti, Savannah Orrill, Joseph Ott, Bahadir Ozus, Jan Pachon, Alexis Paige-Glenn, Jason Paisley, Farideh Pak, Randahl C. Palmer, Kiran Pant, Virginia Pappas, Abby Pardes, So-Yeon Park, Alexis Parker, Karla Parker, Homayon Parsai, Tommy O. Parsons, Pankaj Patel, Amy Patrick, Johnlly G. Pattaserial, Lindsey M. Patton, Taylor J. Patton, Nava R. Paudel, Timothy John Paul, Colin Paulbeck, Olga V. Pen, Cheng Peng, Yuanlin Peng, Carmelo Perez, Dominik Peruško, Alexander Pevsner, Douglas Pfeiffer, Melanie Piantino, Daniel Piatigorski, Rajesh Pidikiti, Natalie Piechowska, Greg Pierce, Tina Pike, Donika Plyku, Robert Pohlman, Mariela Adelaida Porras-Chaverri, Subechhya Pradhan, Guillem Pratx, Chris Proctor, Alexander Pryanichnikov, Diane Pugel, Yue Qiu, Adam C. Quinton, Todd Racine, Andrea Radine, Dustin K. Ragan, Balasubramanian Rajagopalan, Kishore Rajendran, Eric V. Ramirez, Mehdi Ramshad, Vijay K. Rana, Brianne Raulston, Amy K. Readshaw, Hailey Reaux, Ian Reineck, Xuemin Ren, Meral L. Reyhan, Davenport Ria, Matthew J. Riblett, Kenneth M. Richardson, Rebecca F Richardson, Matthew Richeson, Ashlyn Rickard, Adam Riegel, Lynn N. Rill, Miguel A. Rios, E. Russell Ritenour, Scott P. Robertson, Marthony L. Robins, Rebecca Robinson Rey, Steve Rodney, Priscila Rodrigues, Edgardo Rodriguez, Tino Romaguera, Emilie Roncali, Joseph E. Roring, Alison R. Roth, Lawrence N. Rothenberg, Nick Rothwein, Kricia Emilia Ruano Espinoza, Damian DG Rudder, Donald R. Ruegsegger, Erwin W. Ruff, Brandon J. Russell, Frederick Rustad, Narayan Sahoo, Jonathan H. Saleeby, Habeeb H. Saleh, Flavio Salinas Aranda, Steffen Sammet, Daniel Sandoval, Aman Sangal, Joseph P. Santoro, Maíra Santos, Alexis Marie Sanwick, Milind Sardesai, Vikren Sarkar, Duminda Satharasinghe, Jessica L. Saunders, Carmen Sawyers, Sarah B. Scarboro, James Scheuermann, Colleen G. Schinkel, Dale Schippers, Joshua William Schlegel, David J. Schlesinger, Charles Ross Schmidtlein, Erich Schmitz, Jose Schneider, Erich A. Schnell, Lisa Schober, Leah Schubert, Michelle L. Schwer, James Seekamp, Jennifer Seger-Paisley, J. Anthony Seibert, Balaji Selvaraj, Raj N. Selvaraj, Meredith A. Semon-Pomposelli, Lasitha Senadheera, Naima Senhou, Christopher F. Serago, Hananiel Setiawan, Shakil B. Shafique, Aarti Shah, Hina Shah, Alok Shankar, Ryan Shanks, Kritika Sharma, Sunil K. Sharma, Jennifer M. Shealy, Ron Sheen, Gina L. Shelton, Mohammad Ullah Shemanto, Zion Sheng, Andrew J. Shepard, Justin R. Sherman, Kaizhong Shi, Xiaolin Shi, J. Allen Shih, Taciana Soares Shiue, Deborah J. Shumaker, Noah Silverberg, Ramon Alfredo C. Siochi, Amogh Sirniirkar, Marlene Skopec, Michael G. Skowronski, Dana Smetherman, Erika Smith, Eileen Sneeden, Jesse Snyder, James C. So, Emilie Soisson, Nima Soltani, Kwang Hyun Song, Liang Song, Xiaoling Song, Jigar B. Soni, Yashvant C. Soni, Jagadeesh R. Sonnad, Michael A. Speidel, Michael P. Speiser, James D. Speitel, Tanya Spellman, Joseph Patrick Speth, Daniel J. Spitznagel, Sara T. St. James, Alexander Stanforth, George Starkschall, James Stebelton, James P. Steinman, Jonathan M. Stenbeck, Robin L. Stern, Patrick D. Stevens, Erika Stewart, Gary Stinnett, Sarah A. Strand, Keith J. Strauss, Kristen Stryker, Edward Sudentas, Kevinraj N. Sukumar, Orhan H. Suleiman, John L. Sullivan, Paul Robert Sullivan, Mei Sun, Peng Sun, Kumari Sunidhi, Jacob Sunnerberg, Elizabeth A. Swanson, William J. Swanson, Larry E. Sweeney, Sean Swiedom, Gregory Szalkowski, Katsuyuki Taguchi, MohammadAli Tajik-Mansoury, Reza Taleei, Derek Tang, Shengzhang Tang, Mahin Tariq, Jason S. Tavel, Neelima Tellapragada, Alexandra Tellez, Dawn Tellez, Juan Manuel Tellez, Xiaokun Teng, James A. Terry, Biniam Tesfamicael, Confex Test, Aapm Tester, Contex Tester, Namita Thakur, David J. Theel, Kathleen D. Thomas, Emily A. Thompson, Stephen K. Thompson, Daniela Thorwarth, Kevin Tierney, Anders Tingberg, Ragu S. Tirukonda, Robert A. Tokarz, Robert J. Tokarz, Naresh B. Tolani, Brian Tom, Shidong Tong, Ebrahim Torangan, Martin Tornai, Diana Tovmasian, Trung Tran, Bryan Traughber, Samuel Trichter, Sugata Tripathi, Petra Trnkova, Panagiotis Tsiamas, Ryan Tsiao, Haifeng Tu, Philip N Tubiolo, Jeff D. Turley, Adam Turner, PhD, DABR, Conner Ubert, Chibueze Zimuzo Uche, Vincent M. Ulizio, Gnanaprakasam Vadivelu, Hema Vaithianathan, Sunil Valaparla, Fabiola Vallejo Castañeda, Liesbeth Vancoillie, Matt Vanderhoek, Caroline Vanderstraeten, Nancy J. Vazquez, Linda A. Veldkamp, Trevor L. Vent, Anthony M. Ventura, Keith Ver Steeg, Irina Vergalasova, CHENG WANG, Christopher Waite-Jones, Matthew C. Walb, Reuben Waldron, Arlie Vester Walker, Jim Walsh, Alisa I. Walz-Flannigan, Cheng Wang, Helen H. Wang, Hui-Chuan Wang, Jiali Wang, Jian-xiong Wang, Kai Wang, Kyle Wang, Ning Wang, Yuntao Wang, Zhendong Wang, Zhixing Wang, Grace Ward, Sarah M. Way, Rachel L. Waymire, Melvin Weatherly, Charles Travis Webb, Lincoln J. Webb, Jia Wei, Wenbo Wei, Callie Weiant, Miriam S. Weiser, Eric M. Welch, Jered R Wells, Michelle C. Wells, S. Brock Westlund, Gerald A. White, John White, Darunee S. Whitt, David Wikler, Austin Wilkinson, Carly D. Williams, Mark Bennett Williams, Joshua M. Wilson, Keli C. Wilson, Nicholai Wingreen, Joseph Wishart, Alon Witztum, Katherine M. Woch Naheedy, Andy Wolf, Serkalem E. Wondimgezhu, Genevieve N. Wu, Wenhao Wu, Ye Wu, Yuxiang Xing, Li Xiong, Weijun Xiong, Xunyi Xu, Yan Xu, Tianyou Xue, Yanjie Xue, Girijesh K. Yadava, Derek Z. Yaldo, Kaiguo Yan, Yue Yan, Nathan E. Yanasak, Bowen Yang, Ray Yang, Xiaocheng Yang, Yun Yang, Yunze Yang, Bin Yao, Yuan (John) Yao, Anna N Yaroslavsky, Feng-Ju Yeh, Susanne Yerich, Michael V. Yester, Xiaofei Ying, Tekeste Yohannis, Tony Younes, Eyesha Younus, Jialu Yu, Justin Yu, Yan Yu, Pui Kuen Yuen, Joshua P. Yung, Steve Yuvan, Mehran Miron Zaini, Ramtin Zakikhani, Lee Anne Zarger, Merissa Zeman, Lisa Zent, Di Zhang, Dongqing Zhang, Hao Zhang, Jun Zhang, Lei Zhang, Lu Zhang, Maochen Zhang, Peng Zhang, Peng Zhang, Qingyun Zhang, Xin Zhang, Yi Zhang, Yinghui Zhang, Yongbin Zhang, Zhongwei Zhang, Bo Zhao, Xuandong Zhao, Yizhou Zhao, Weiping Zheng, Yi Zheng, Troy Zhou, Xiangzhi Zhou, Xiaohong Joe Zhou, Yuwei Zhou, Jin Zhu, Mingyao Zhu, Eric C. Zickgraf, John R. Zullo, Piotr Zygmanski, Leo van Battum

Affiliation: DTC Consultants, NL Health, Dartmouth Hitchcock Medical Center, ProCure Proton Therapy Center, Medical & Radiation Physics, Inc, Augusta University, Genesis Healthcare Partners, Michigan Medicine, Washington DC VA Medical Center, VA Medical Center, Mercy Southeast Hospital, Food And Drug Administration, University of Iowa, Advanced Radiation Physics Service, Inc, University of Pittsburgh, University of Wisconsin, Wellspan Health, Good Samaritan Hospital, Howard University Hospital, St. Mary's Memorial Health Center, Penn State Milton S. Hershey Med Ctr., New York Weill Cornell Medical Ctr, X-Ray Computations, Inc., US Navy, Penn State Health, Kelsey Seybold Clinic, Advocate Aurora, Fresno Cancer Center, Central Alabama Radiation Oncology, Riverside Methodist Hospital Ohio Health, Alliance Medical Physics, OCSRI, AAPM, University of Minnesota, University of Virginia Health System, PGIMER, Barrigel, Johns Hopkins Univ, Appex Physics Partners, BoxElder Research, University of Oklahoma Health Sciences Center, Sanford Roger Maris Cancer Center, Berkshire Medical Center, New York Weill Cornell Medicine, Mobimed Technologies, University of Chicago Medicine, Johns Hopkins Medicine, Maimonides Medical Center, Nuvance Health - Vassar Brothers, Crozer Keystone Health System, Karmanos/McLaren, Vanderbilt University, Panhandle Cancer Care Center, The University of Michigan, Piedmont Healthcare, Gamma Medical Physics LLC, Mississippi Baptist Medical Center, Astarita Associates Inc, Landauer Medical Physics, RPS Oncology, Zhejiang University, University of North Carolina School of Medicine, University of Kentucky HealthCare, Peninsula Regional Medical Center, Varian Advanced Oncology Solutions, New York Proton Center, Wake Forest University Medical Center, Rutgers Robert Wood Johnson Medical School, Tx Oncology, Lewis Hall Singletary Oncology Center (John D. Archbold Hospital), Medical Physics Services, University of New Mexico, UPMC Cancer Center, Medical Physics Solutions, LLC, ECU Health, Evercare Hospital Chattogram, Mercy Cancer Center, Sharp Grossmont Hospital, West Virginia University, Virginia Commonwealth University Medical Center, Thomas Jefferson University, Centennial Medical Physics, LLC, University of California, Davis, University of Miami, Varian, Inc., UAB Medical Center, Wellspan health, Cleveland Clinic Foundation, Procure Treatment Center, Retired FDA, Tufts Medical Center, Virginia Commonwealth University, Germantown Academy, Hartford Hospital, Cleveland Clinic Florida, Billings Clinic, Imalogix, University of Wisconsin - Madison, Dana Farber Cancer Institute, Massachusetts General Hospital, Johns Hopkins University, GenensisCare, VARIAN Siemens Healthineers, MedStar Washington Hospital, Illawarra Cancer Care Center, Duke Health, Corewell Health, Columbia University, Johns Hopkins, Baylor Scott & White Health, Ascension Saint Thomas Rutherford Hospital, Varian, a Siemens Healthineers company, Rabin Medical Center, Albany - Stratton VA, Florida Cancer Specialists at Tampa Cancer Center, Baylor St Lukes Medical Center, Baylor College of Medicine, Christiana Care Health System, West Physics, Mayo Clinic Arizona, Emory University, University of Pittsburgh Medical Center, Brigham and Women's Hospital, UCLA, CoxHealth, Starsino Medical Technologies Co Ltd, University of Utah Hospitals, Lahey Health Medical Center, Paul Scherrer Institute (PSI), Karmanos Cancer Institute, Radcom Associates, LLC, Ascension Wisconsin, The University of Alabama at Birmingham, Winter Park Cancer Center, Louisiana State University, UT Health San Antonio, Intermountain Health, Penn Medicine/Lancaster General Health, Elekta Xoft, University of KY HealthCare, Rutgers, Cancer Institute of New Jersey, Real Time Tomography LLC, Toronto Metropolitan University, UCSD, Dartmouth College, Ascension St. Thomas Rutherford hospital, City of Hope, Radiation Management Associates, Levine Cancer Institute, Atrium Health, Varian Medical Systems, Blount Memorial Hospital, Penn State University, Therapy Physics, Inc., Northwest Community Hospital, Duke University Medical Center, Advent Health, Miami Cancer Institute, Washington State Department of Health, Lantheus Medical Imaging, Chesapeake Potomac Regional Cancer Center, MRP Inc., University of Chicago, University of Tennessee Medical Center, Huntsman Cancer Institude, University of Utah, Oregon Health and Science University, Hutchinson Regional Medical Center, Winchester Medical Center, WellSpring Oncology, Medical School of East Carolina Univ, Weill Cornell Medical Center, UPMC Hillman Cancer Centers, Springfield Clinic, CaliberMRI, Inc., Prisma Health, Helen F. Graham Cancer Center, ChristianaCare, Upstate Medical Physics, PC, Loma Linda University Medical Center, Radpocket LLC, RayzeBio, St. Peter's Health Partners, MJS Medical Physics Inc., UCHealth, Astarita Associates, Image X Institute, School of Health Sciences, University of Sydney, Oregon Urology Institute, Seoul National University Hospital, GenesisCare, Reid Health, National Institutes of Health (NIH), Bayhealth Medical Center, Albany Medical College, Advocate Radiation Oncology, Rush, Krueger-Gilbert Health Physics, Sentara Healthcare, Accuray Incorporated, CTSI, RTI Group North America, University of Louisville, Thomas Jefferson University Hospital, NCI, West Physics Consulting, LLC, Boston Children’s Hospital, CHOP, Greater Baltimore Medical Center, Florida Cancer Specialist & Research Institute, Radformation, Texas Oncology South Austin Cancer Center, Mosaic Life Care Cancer Center, University of Virginia, CPDS, Ravenel Oncology Center, M Health Fairview, Torrance Memorial Medical Center, RJK Medical Physics, Inc., NYU Langone-Long Island, Trinity CancerCare Center, Bryn Mawr Hospital, Sanford Health, University of Michigan Health Systems, One Physics - Ohio Medical Physics Consulting, West Michigan Cancer Center, University Hospitals Cleveland Medical Center, Levine Cancer Institute/Atrium Health, Advanced Biophotonics Laboratory, University of Massachusetts Lowell, UConn Health, U.S. Nuclear Regulatory Commission, Wayne State University, University of Oklahoma Health Science Center, Houston Methodist Hospital, Varian, Arizona Center for Cancer Care, NIH Clinical Center, Stanford University, Hospital of the University of Pennsylvania, Peel Regional Cancer Center, Credit Valley Hospital, University of Alabama Birmingham, Lark Physics, Ackerman Cancer Center, Southern District Health Board, Milestone Medical Physics Group, UTHealth Houston McGovern Medical School, Rutgers University, West County Radiological Group, Mayo Clinic, Philips Healthcare, University of Vermont Medical Center, Novant Health at Presbyterian Medical Center, Harvard Medical School, Ratio Therapeutics, Naval Medical Center Portsmouth, University Colorado Denver, School of Medicine, Sutter Santa Cruz Radiation Oncology, Radiophysics Associates, Northside Hospital, SolutionHealth, University of Virginia Health Systems, Johns Hopkins School of Medicine, Austin Health, UPMC, St. Joseph Mercy Health System, Cancer Center of Hawaii, Centra Health, Aspekt Solutions, Winter Haven Hospital, Henry Ford Hospital System, Medical University of South Carolina, Maine Medical Center, Phoenixville Hospital, National Institutes of Health, Associated Medical Professionals, Gundersen Health System, St. Luke's University Health Network, Univesity of Victoria, Department of Radiation Oncology, Stanford University School of Medicine, Washington University in St. Louis, Queen's Medical Center, West O'ahu, Canon Medical Research USA, Inc., Robert Wood Johnson University Hospital, UVA Health System, Section for Biomedical Physics, Department of Radiation Oncology, University Hospital and Medical Faculty, Eberhard Karls University Tübingen, Centennial Medical Physics, McLaren Cancer Institute, Cancer Care Group, Texas Oncology-Tyler, CTSI Oncology Practice Solutions, a varian company, Bank of Cyprus Oncology Centre, Columbus Regional Hospital, Central Florida Cancer Insititute, Texas Oncology - San Antonio, The Ohio State University, Stony Brook University, Greenwich Hospital, INOVA Schar Cancer Institute, Marsden Medical Physics Associates, Allegheny Health Network, Geisinger Health System, University of Maryland Medical System, Texas Oncology, Mount Sinai Medical Center, TrueNorth Medical Physics, Mallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, Houston Methodist Hospital, Houston, TX, Martin Memorial Medical Center, Yale University School of Medicine, Comprehensive Cancer Centers of Nevada, ASR Institute for Cancer Care, Research & Rehabilitation, University of Louisville Brown Cancer Center, Jaeger Corporation, UC San Francisco, Inova Hospital at Fairfax, Upstate Medical Physics, Cedars-Sinai Medical Center, Brown University Health, Texas Oncology-Denton, Assarian Cancer Center, HCA Healthcare, San Diego State University, Cooper University HealthCare, LVeldkamp MedPhys Services, LLC, Morristown Medical Center, Atlantic Health System, OMPC Therapy, LLC & OMPC Diagnostic, LLC, Defense Health Agency, Radiation Oncology, Medical College of Wisconsin, UT Southwestern Medical Center, Kaiser Permanente Bellflower Medical Center, Roswell Park Comprehensive Cancer Center, University of Victoria, MD Anderson Cancer Center at Cooper, Siemens Healthineers, Monmouth Medical Center, Memorial Sloan Kettering Cancer Center, Ironwood Cancer & Research Centers, University of Cincinnati, School of Medical Sciences, Fujita Health University, University of Kentucky/UK HealthCare, University of California, San Francisco, Instituto Nacional do Cancer, Brazil, IBA Dosimetry GmbH, Westchester Medical Center, Ohio State Univ, Houston Methodist, Medical College of Wisconsin, Columbia University Medical Center, Department of Radiation Oncology, College of Medicine, University of Arkansas for Medical Sciences, UT MD Anderson Cancer Center, DFCI/BWCC south shore, Providence Cancer Center, Memorial Sloan-Kettering Cancer Center, American Association of Physicists in Medicine, Lynn Cancer Institute - Radiation Oncology, Renown Health, Purdue Univ, Beth Israel Deaconess Medical Center, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Holy Family Hospital, OhioHealth, IBA Dosimetry, Memorial Hospital Gulfport, University of Florida, George Washington Univ, University of Cincinnati Medical Center, Hubbard, Zickgraf, & Broadbent, Accuray Inc, UVRMC, MIM Software, Massachusetts General Hospital and Harvard Medical School, Mem. Sloan Kettering Cancer Ctr, UF Health Proton Therapy Institute, California Medical Physics, Inc., Henry Ford Health, UPMC Hillman Cancer Center, Vanderbilt University School of Medicine, Saddleback Memorial Medical Center, Stony Brook University Medical Center, University of Pennslyvania, TOP Physics Consulting, Nuvance/Norwalk Hospital, Oregon Health & Science Univ, Brigham & Women's Hospital, University of Pennsylvania, McLaren – Greater Lansing, American Board of Radiology, Penn Medicine | Virtua Radiation Oncology, University of Tennessee, OneOncology, University of Colorado, Indiana University Medical Center, Stronach Regional Cancer Centre, Yale New Haven Health, Vanderbilt University Medical Center, Emory Healthcare / Winship Cancer Institute, Cape Fear Valley Radiation Oncology, Northwell Health, Sutter Health, Virginia Mason Medical Center, MUSC Health- Florence Medical Center, Departement of Radiation Oncology, Curie Institute, Paris, University of Michigan, MD Anderson Cancer Center, University of Alabama at Birmingham, Radiology Inc., Cedars Sinai Hospital, Roswell Park Cancer Institute, Duke University Health System, VA Hospital, DVA Medical Ctr., JFK Medical Center, Mount Sinai West, National Cancer Institute, Chung Nam National University Sejong Hospital, Indiana Univesity, AdventHealth Daytona Beach, Orlando Health, Clinical Research Institute HUS, Northwest Medical Physics Center, University of Pennsylvania, Penn Medicine, Kettering Health Network, Children's Mercy Kansas City, IBA, UMass Memorial Hospital, US Oncology, Kaiser Permanente Southern California Medical Group, The Queen's Health System, NewYork-Presbyterian, Miami Valley Hospital, Karlsruhe Institute of Technology, Piedmont Hospital, Accuray Inc., VARIAN - Advanced Oncology Solutions, GE Healthcare, Virtua Health, Northwestern Medicine Chicago Proton Center, CARO/Montgomery Cancer Center, Walter Reed National Military Medical Center, InterMountain Health Care, Englewood Hospital and Medical Center, Henry Ford Health System, Fluke Health Solutions, Texas Oncology, PA, Inova Alexandria Hospital, New Milford Hospital, Fox Chase Cancer Center, Radiation Therapy and Cancer Inst, Penn State College of Medicine, University of California San Francisco, Unity of Oncologic Therapy S.A., Canon Medical Systems USA, Kaiser Permanente, Baptist Health Paducah, Salina Regional Health, Centre d'Oncologie de la Cote Basque, Minneapolis Radiation Oncology, Coastal Carolina Radiation Oncology, Saint Francis Hospital, Advocate Christ Medical Ctr, Universidad de Costa Rica, CAMP, Blessing Hospital, Texas Oncology Cancer Ctr, CommonSpirit Health, Navy Medical Forces Atlantic, Regions Hospital, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Methodist Hospital, Champlain Valley Physicians Hospital, Mayo Clinic Jacksonville, OHSU, Promedica Health System, Arthur JE Child Comprehensive Cancer Centre, Rhode Island Hospital / Warren Alpert Medical, UPMC Pinnacle Health, Vassar Brothers Hospital, McLeod Regional Medical Center, RJ Tokarz MIRS, St. Francis Hospital, Astarita Associates, Inc., UC Davis Medical Center, Mount Nittany Medical Center, Covenant Radiation Center, National Institute of Standards and Technology, AdventHealth Orlando, St Helena Hospital, Icon Cancer Centre, University of Washington, Indiana University, TrueNorth Medical Physics LLC, Medstar Georgetown University Hospital, Harold Alfond Center for Cancer Care, MN Oncology, Jupiter Medical Center, GE HealthCare, Rochester General Hospital, Piedmont Health, Atrium Health, Minneapolis VA Health Care System, CentraCare Health System, OMPC Diagnostic LLC, Evergreen Health Medical Center, CAMC Cancer Center - Beckley, University of Kansas Medical Center, Avera McKennan, Cleveland Clinic, Louisiana Tech University

Abstract Preview: N/A...

Next Generation Nanoparticles for Fractionated MRI-Guided Radiation Therapy

Authors: Stephanie Bennett, Ross I. Berbeco, Guillaume Bort, Needa Brown, Lena Carmes, Sandrine Dufort, Michael John Lavelle, Geraldine Le Duc, Francois Lux, Toby Morris, Zeinaf Muradova, Andrea Protti, Olivier Tillement

Affiliation: University de Lyon, NH TherAGuIX, University of Massachsetts Lowell and Dana-Farber Cancer Institute Boston, Department of Radiation & Cellular Oncology, University of Chicago, University of Central Florida, Department of Radiation Oncology, Dana-Farber/Brigham and Women’s Cancer Center, Harvard Medical School, NH TherAguix, Universite de Lyon, Brigham and Women's Hospital, Dana-Farber Cancer Institute

Abstract Preview: Purpose: AGuIX is a theranostic Gd-based nanoparticle currently under phase-2 clinical testing where patients receive 2-3 doses at 1-week intervals prior to imaging and irradiation. AGuIX-Bi is a new ...

Nnae: Automating Anomaly Detection and Quality Assurance in Medical Image Segmentation

Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose:
Deep learning-based automatic medical image segmentation is increasingly employed in clinical practice, significantly reducing manual workload. However, verifying segmentation results rema...

Non-Invasive Ferumoxytol MRI Evaluation of Dual Tumors Response for Hypoxia Region after Radiotherapy

Authors: Deng-Yuan Chang, Matthew L. Scarpelli

Affiliation: Purdue University

Abstract Preview: Purpose: Tumor-associated macrophages (TAMs) can be assessed by Ferumoxytol-MRI in breast cancer because they are negatively correlated with the prognosis of patient outcome. However, some studies hav...

Novel Approach to Improve Treatment Planning Process for Mixed Fractionation Schemes on ZAP-X

Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang

Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center

Abstract Preview: Purpose: Using mixed fractionation schemes is a common technique in treating CNS lesions. This article describes an innovative plan-and-split approach for more efficient planning on the ZAP-X and thus...

Objective Verification of Mechanical and Radiation Isocenters Independent of Setup

Authors: Jonathan Dowell, Wei Luo, Shane McCarthy, Janelle A. Molloy, Markus Murphy

Affiliation: University of Kentucky, Department of Radiation Medicine, Iridesce Solutions, Inc.

Abstract Preview: Purpose: The novel machine quality assurance (QA) device nüFilm (Iridesce Solutions, Lexington KY) allows for an objective assessment of light and radiation fields independent of setup. Herein, the ab...

On Designing a Vascular Flow Phantom for Contrast-Enhanced Ultrasound Imaging

Authors: Kevin M Brom, Josep Chorro Bas, RosaAnna Chorro Bas, Andres Climent Rubio, Jaydev K. Dave, Tobias Kummer, Larissa Shiue, Donald J Tradup

Affiliation: Mayo Clinic, Prehospital Critical Care Training Group

Abstract Preview: Purpose: To design and evaluate the functionality of a vascular flow phantom for contrast-enhanced ultrasound imaging (CEUS).

Methods: A microcontroller-generated signal was amplified by a cust...

Online Active Learning Strategies for Global Medical Physics Education: A Scoping Review

Authors: Mary Gronberg, Kelly Kisling, Ana Maria Marques da Silva

Affiliation: University of California, San Diego, The University of Texas Southwestern Medical Center, Pontifical Catholic University of Rio Grande do Sul

Abstract Preview: Purpose: To evaluate the current status of online teaching in medical physics and identify effective active learning strategies for global medical physics education.
Methods: A scoping review was c...

Optimal Lattice Design for Spatially Fractionated Radiotherapy (SFRT) of Brain Metastasis in Gamma Knife (GK)

Authors: Brankica Andelic, Young-Bin Cho, Tara M. Gray, Andrew Robert Hadfield, Hakan Nordstrom

Affiliation: Elekta, Cleveland Clinic

Abstract Preview: Purpose: Spatially Fractionated Radiotherapy (SFRT) requires highly modulated dose distribution inside a tumor volume optimized using sets of planning structure of spheres in a lattice arrangement. To...

Optimizing Fractionation Schedules for De-Escalation Radiotherapy in Head and Neck Cancers Using Deep Reinforcement Learning

Authors: Zhongjie Lu

Affiliation: Department of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine

Abstract Preview: Purpose: Patients with locally-advanced head and neck squamous cell carcinomas(HNSCCs), particularly those related to human papillomavirus(HPV), often achieve good locoregional control(LRC), yet they ...

Optimizing Motion Management QA: Clinical Integration of Aapm TG-306 for the Radixact Synchrony System

Authors: Hulya Ozdemir Buss, Jeffrey Geiger, Kim Howard, Julius G. Ojwang, Neelu Soni

Affiliation: Mercy Hospital Springfield

Abstract Preview: Purpose: The Radixact Synchrony system integrates real-time motion tracking and compensates to improve treatment accuracy for moving targets. This study presents a streamlined and efficient quality as...

Optimizing Quality Assurance CT Scan Frequency in Proton Therapy: Reducing Excess Dose While Maintaining Treatment Accuracy

Authors: Curtiland Deville, Rachel B. Ger, Heng Li, Todd R. McNutt

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: Proton therapy patients receive quality assurance CT scans (QACTs) during treatment to verify dosimetric accuracy and determine adaptive therapy needs as proton treatments are highly sensitiv...

Optimizing Timing of Physics Consults for Proton Prostate Therapy: Improving Patient Experience and Operational Efficiency

Authors: Charles D. Bloch, Stephen R. Bowen, Bing-Hao Chiang, Alex Egan, Eric C. Ford, Sharareh Koufigar, Dominic A. Maes, Juergen Meyer, Sharon Pai, Frank Rafie, Rajesh Regmi, Jatinder Saini, George A. Sandison, Marco Schwarz, Bishwambhar Sengupta, Tony P. Wong

Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Physics, University of Washington

Abstract Preview: Purpose: This study aimed to optimize the strategy and timing of physics consults for proton prostate patients to improve the patient experience and resource utilization in our radiation oncology depa...

Optimizing Vessel Wall Visualization Using a Novel Black-Blood CT Technique on Craniocervical CT Angiography

Authors: Xiaohu Li, Jianjun Shen, Guozhi Zhang, Sihua Zhong, Jingjie Zhou

Affiliation: United Imaging Healthcare

Abstract Preview: Purpose:
Visualization of carotid artery vessel wall on computed tomography angiography (CTA) imaging is challenging. This study aims to develop a novel post-processing technique, black-blood compu...

Optimizing the Collimator Angles in Radiation Isocenter Localization Using Winston-Lutz Tests

Authors: Weiliang Du

Affiliation: The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Winston-Lutz (WL) tests are often used to localize the radiation isocenter of a linac. The selection of gantry and collimator angles can affect the accuracy of the resulting isocenter. The ef...

Overview of the AAPM/EFOMP Task Group 427: Technical Guidelines for the Use of Proton Therapy in Clinical Trials

Authors: Stella Flampouri

Affiliation: Emory University

Abstract Preview: N/A...

Overview of the EFOMP Particle Therapy Special Interest Group (PT_SIG)

Authors: Richard A. Amos

Affiliation: University College London

Abstract Preview: N/A...

Parameterized 4D Deformable Registration (p4Dreg) in Abdominal 4DCT Scans

Authors: Edward Robert Criscuolo, Deshan Yang

Affiliation: Duke University, Department of Radiation Oncology, Duke University

Abstract Preview: Purpose:
Deformable registration of 4DCT images has many clinical applications, but current methods are unreliable and can produce dangerous errors. Iterative, parametrized image registration does ...

Personalized Radiotherapy: A Novel Approach to Multi-Criteria Optimization with Patient-Specific Risk Integration

Authors: Ali Ajdari, Thomas R. Bortfeld, Zhongxing Liao, Mara Schubert, Katrin Teichert

Affiliation: The University of Texas MD Anderson Cancer Center, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Fraunhofer ITWM

Abstract Preview: Purpose: Radiotherapy (RT) treatment planning often involves solving a multi-criteria optimization (MCO) problem. Conventionally, MCO considers a set of generic (population-wide) dosimetric criteria, ...

Phase One Randomized Two-Arm Dose Escalation of Flash RT in Veterinary Canine Osteosarcoma: Trial Design & Initial Results

Authors: Wesley S. Culberson, Aleksandra Ilina, Brian W Pogue, Matthew Reed, Connor Strainis, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel

Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin–Madison, University of Wisconsin-Madison, University of Wisconsin - Madison

Abstract Preview: Purpose: FLASH radiotherapy reduces skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR), while preserving damage to tumor tissue. The FLASH effec...

Portable Label-Free Raman Spectroscopy for Complementary Evaluation of Radiation Induced Tissue Damage

Authors: Marwan Belal AbuHaija, Anis Ahmad, Chase Prescott Anderson, Nesrin Dogan, John C. Ford, Alan Pollack, Junwei Shi, Jorge D Vega, Gabriel Enrique de Hostos

Affiliation: University of Miami, University of Miami Sylvester Comprehensive Cancer Center

Abstract Preview: Purpose: Raman Spectroscopy (RS) is a non-invasive, label free imaging modality that gathers intrinsic molecular vibrational information. Portable RS systems expand affordability and convenience, supp...

Predicting Elective Pelvic Nodal Volumes with Deep Learning: A Tool to Facilitate Peer Review

Authors: Brian M. Anderson, Shiva K. Das, Meagan Foster, Anirudh Karunaker, Lawrence B. Marks, Lukasz Mazur, Michael Repka

Affiliation: UNC Chapel HIll, University of North Carolina at Chapel Hill, UNC School of Medicine, University of North Carolina

Abstract Preview: Purpose: Development of a peer review segmentation check system to identify deviations in physician contours of standard risk pelvic lymph nodes in patients receiving radiation therapy for prostate an...

Predictive Quality of Differing Body Size Measurands for Radiation Risk Estimation in CT Imaging: A Virtual Trial Study

Authors: Njood Alsaihati, Francesco Ria, Ehsan Samei, Justin B. Solomon, Martina Talarico, Jered Wells

Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Radiation dose and associated risk in X-ray imaging is principally informed by patient size, further used in Computed Tomography (CT) to achieve prescribed image quality levels through tube c...

Preliminary Evaluation of Ultrasound-Derived Fat Fraction Reliability in a Pediatric Cohort

Authors: Lizbeth Ayala-Dominguez, Aaron L Carrel, Diego Hernando, Gabrielle L Hoffmann, Amber Possell, Ivan M. Rosado-Mendez, Jiayi Tang, Andrew Wentland

Affiliation: Department of Pediatrics, University of Wisconsin-Madison, Department of Radiology, University of Wisconsin-Madison, Department of Medical Physics, University of Wisconsin-Madison, Departments of Medical Physics and Radiology, University of Wisconsin-Madison

Abstract Preview: Purpose: Metabolic dysfunction-associated steatotic liver disease (MAFLD) is the leading cause of chronic liver disease in children. While biopsy remains the diagnostic standard, non-invasive imaging ...

Preliminary Evaluation of a Gpτ-Based Medical Physics Education Tool

Authors: Ramesh Boggula, Jay W. Burmeister, Michael Joiner

Affiliation: Wayne State University, Karmanos Cancer Center, Gershenson ROC, Wayne State University School of Medicine

Abstract Preview: Purpose: Recent advances in large language models such as ChatGPT offer new possibilities for supplementing traditional teaching methods. In this study, we developed a custom GPT-powered tool freely a...

Principles of Medical Imaging: An AI-Driven Interdisciplinary Course Bridging Academia, Industry, and Clinical Practice

Authors: Ning Wen, Zheyu Zhang

Affiliation: Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai Jiaotong University

Abstract Preview: Purpose: The graduate course, “Principles of Medical Imaging,” aims to advance imaging technology by integrating artificial intelligence (AI) into medical imaging. It bridges interdisciplinary fields,...

Prospective Hazard Analysis in Radiation Therapy – a Systematic Review

Authors: Jeremy T. Booth, Sonja Dieterich, Jonathan Hindmarsh, Paul J. Keall

Affiliation: Northern Sydney Cancer Centre, Royal North Shore Hospital, UC Davis Medical Center, Image X Institute, Faculty of Medicine and Health, The University of Sydney

Abstract Preview: Purpose: Prospective hazard analysis (PHA) is a core medical physics function. PHA was investigated by AAPM Task Group 100 for the purpose of keeping patients safe and assessing the risks of novel tec...

Prospective Organ-Level Dose Estimation in CT Imaging Using Scout-Net: A Comparison with Established Methods

Authors: Maria Jose Medrano, Grant Stevens, Liyan Sun, Justin Ruey Tse, Adam S. Wang, Sen Wang

Affiliation: Department of Radiology, Stanford University, GE HealthCare, Stanford University

Abstract Preview: Purpose: Patient exposure to ionizing radiation is a major concern in CT imaging. Size-specific dose estimation methods can prospectively estimate organ-level radiation doses based on patient sizes an...

Quantification of Global Dosimetry Audit Performance: Assessing the Sensitivity and Specificity of Dosimetry Audits to Establish Reciprocity Among Different International Clinical Trials Credentialing Organizations

Authors: Fre'Etta Brooks, Catharine H Clark, Patricia Diez, Peter B. Greer, Hideaki Hirashima, Rebecca M. Howell, Mohammad Hussein, Stephen F. Kry, Joerg Lehmann, Jessica Lye, Mitsuhiro Nakamura, Christopher L. Nelson, Rushil Patel, Christine Peterson, Julianne M. Pollard-Larkin

Affiliation: Kyoto University, The University of Texas MD Anderson Cancer Center, Radiotherapy Trials Quality Assurance Group, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Medical Physics & Biomedical Engineering, University College London, Metrology for Medical Physics, National Physical Laboratory, Austin Health, University of Washington Medical Center, University of Newcastle

Abstract Preview: Purpose: To assess the consistency of end-to-end dosimetry audits currently used by different international clinical trial QA organizations with the goal of harmonizing audits and reducing audit overl...

Quantification of Iodine and Calcium Materials through HU Spectral Curve Analysis in Dual-Energy CT for Radiotherapy Planning

Authors: Sean L. Berry, Weixing Cai, Laura I. Cervino, Maria F. Chan, Yabo Fu, Puneeth Iyengar, Hsiang-Chi Kuo, Nancy Lee, Tianfang Li, Xiang Li, Jean M. Moran

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Iodine maps derived from Dual-Energy CT (DECT) provide critical biological information for radiotherapy treatment planning, but clinical iodine maps often mistakenly include bones due to insu...

Quantifying Uncertainties in Radiation Risk and Performance-Based Clinical Risk Assessment in Clinical Computed Tomography

Authors: Em Harkness, Francesco Ria, Ehsan Samei

Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose:
A recently introduced mathematical method quantifies performance-based clinical risk to create a risk-to-risk assessment with radiation risk, rendering the so-called total risk. However, t...

Quantitative Analysis of Three Strategies for CTPA Scan Timing Optimization

Authors: Zahra Alyani Nezhad, Carrie Bartels, Rachel Bladorn, Sean D. Rose, Kelsey Schluter, Timothy P. Szczykutowicz

Affiliation: Departments of Radiology and Medical Physics, University Wisconsin-Madison, University of Wisconsin Madison, University of Wisconsin-Madison, University of Texas at Houston Medical School, University of Wisonsin-Madison

Abstract Preview: Purpose: Pulmonary embolism is a life-threatening condition, and computed tomography pulmonary angiography (CTPA) is the gold standard for diagnosis. Inadequate contrast enhancement often leads to a h...

Quantitative Assessment of Iodine Detectability As a Function of Tissue Density, Thickness and Dose in Contrast-Enhanced Mammography

Authors: Jeffrey S. Nelson, Raj Kumar Panta, Megan K. Russ, Ehsan Samei

Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Contrast-enhanced mammography (CEM) enhances tumor detection by utilizing energy-dependent information from iodinated contrast agents. However, there is a lack of quantitative techniques to a...

Radiation Dose Variability and Predictability Versus PTV Volume and Anatomical Site

Authors: Lars Ewell, Russell J. Hamilton

Affiliation: Banner University Medical Group, Bannerhealth

Abstract Preview: Purpose: To estimate the variability and predictability of radiation dose as a function of the planning target volume (PTV) size and the anatomical sites of head & neck, brain and prostate.
Methods...

Radiodynamic Therapy: Inhibiting Metastases of Small Cell Lung Cancer In Vivo

Authors: Lili Chen, Andy T. Clark, Dusica Cvetkovic, Chang Ming Charlie Ma, Dae-Myoung Yang

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose: Radiodynamic therapy (RDT) shows promise as a strategy to inhibit the metastasis of premetastatic small cell lung cancer (SCLC). This study evaluates the therapeutic effect of RDT in inhibiti...

Raman Spectroscopy Identifies Biomolecular Differences between Caucasian and African American Prostate Cancer Patients

Authors: Nrusingh C. Biswal, Manas R. Gartia, Maria Iftesum, Sanjit K. Roy, Gyana Ranjan Sahoo, Elnaz Sheikh, Hem D. Shukla, Madhur Srivastava

Affiliation: Department of Chemistry and Chemical Biology, Cornell University, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Mechanical and Industrial Engineering, Louisiana State University

Abstract Preview: Purpose: Prostate cancer incidence and mortality levels in African-American men are the highest among all ethnic groups. This points to the role of biological factors in driving disparate outcomes. He...

Real Time Monte Carlo Dose Calculation for Clinical Cyberknife Radiation Therapy Based on Deep Learning Diffusion Model

Authors: Ruiyan Du, He Huang, Mingzhu Li, Ying Li, Hongyu Lin, Wei Liu, Shihuan Qin, Yiming Ren, Hui Xu, Lian Zhang, Xiao Zhang, Zunhao Zhang

Affiliation: Department of Radiation Oncology, Mayo Clinic, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Department of Oncology, The First Hospital of Hebei Medical University

Abstract Preview: Purpose: Monte Carlo (MC) dose calculation is the gold standard in clinical CyberKnife radiation therapy (RT), considering its steep dose gradients and high-freedom non-coplanar beam angles, but extre...

Real-Time Observation of Radiation-Induced DNA Damage for Radiopharmaceuticals

Authors: Denis Bergeron, Brittany Broder, Sean Jollota, Ahtesham Ullah Khan, Michael Lamontagne, Joseph W. Robertson

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Biophysics and Biomedical Research Group, Microsystems and Nanotechnology Division, National Institute of Standards and Technology, National Institute of Standards and Technology

Abstract Preview: Purpose: We present new methodology for real-time measurement of radiation-induced DNA damage caused by radiopharmaceuticals. Building on previous efforts to measure DNA fragmentation with nanopore se...

Reconstructing Radiopharmaceutical Distributions Using Coded Aperture Tomography with Photon Counting Detector

Authors: David P. Adam, Xun Jia, Youfang Lai, Yuncheng Zhong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University

Abstract Preview: Purpose: Radiopharmaceutical therapy is experiencing a resurgence in interest due to its potential of treating widespread metastatic disease in a patient-specific manner. Accurately measuring and desc...

Rectal Spacer Injection on the Day of HDR Prostate Brachytherapy Enhances Dosimetry and Reduces Rectal Dose for Patients Receiving Combined Brachytherapy and EBRT.

Authors: Francis A Asamoah, David D. Campos, Jordan A Holmes, Ke Colin Huang, Omar Ishaq, Sook Kien Ng, Arpan Prabhu, Edwin Quashie, Yong Yue

Affiliation: Indiana University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose: Evaluate a novel rectal spacer workflow with spacer injection during brachytherapy to streamline logistics, reduce hospital visits and costs, and compare the benefits of SpaceOAR Vue and Barr...

Rectangular Aperture-Based Beam Orientation Optimization for 4π Non-Coplanar Small Animal IMRT Delivery

Authors: Dante PI Capaldi, Lu Jiang, Qihui Lyu, Ke Sheng

Affiliation: Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose:
Preclinical small animal studies help understand radiation-induced biological responses, toxicities, and mechanisms, facilitating the translation of new therapies to patient treatment. Int...

Region-Specific Structure-Function Coupling Alterations in Parkinson’s Disease: Insights from Multi-Modal MRI

Authors: Yifei Hao, Ting Huang, Wenxuan Li, Xiang Li, Manju Liu, Rong Liu, Tao Peng, Yulu Wu, Fang-Fang Yin, Lei Zhang, Yaogong Zhang, Jiangtao Zhu

Affiliation: Duke University, Department of Radiology, The Second Affiliated Hospital of Soochow University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: This study investigates the alterations in structure-function coupling (SC-FC) networks in Parkinson’s disease (PD) patients, focusing on region-specific disruptions and compensatory mechanis...

Reliable Markerless Lung Tumor Tracking with Built-in Patient-Specific Quality Assurance

Authors: Weixing Cai, Laura I. Cervino, Qiyong Fan, Yabo Fu, Tianfang Li, Xiang Li, Jean M. Moran, Hai Pham, Pengpeng Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: AAPM Task Group Report 273 emphasizes the importance of rigorous validation to ensure the generalizability and robustness of machine learning-based clinical tools before their implementation ...

Retrospective MRI-Based Investigation of Bulboclitoris and Vaginal Canal Morphological and Physiological Changes in GYN Patients Treated with External Beam Radiation Therapy

Authors: Diandra Ayala-Peacock, Junzo Chino, Oana I. Craciunescu, Allison Jones, Kyle J. Lafata, Kim Light, Sheridan G. Meltsner, Jack B Stevens

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Duke University Medical Center

Abstract Preview: Purpose: This study aims to develop an MR-based method that retrospectively correlates longitudinal changes in morphology and physiology for the bulboclitoris and vaginal canal with dose received duri...

Simultaneous Motion Estimation and Image Reconstruction with Spatiotemporal Implicit Neural Representation Initial (STINR-SMEIR) for Gas Bubble Motion Artifact Reduction in on-Board CBCT Imaging

Authors: Hua-Chieh Shao, Shanshan Tang, Jing Wang, Kai Wang, You Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, University of Maryland Medical Center

Abstract Preview: Purpose: Artifacts caused by gas bubble movement in the gastrointestinal tract can severely degrade the image quality of on-board abdominal cone-beam computed tomography (CBCT), impacting its utility ...

Status of Medical Physics Education in LMIC and IOMP Initiatives - Way Forward

Authors: Arun Chougule

Affiliation: Swasthya Kalyan Group

Abstract Preview: N/A...

Supercomputing-Enabled CT Virtual Imaging Trials: A Population-Scale Pilot Study

Authors: Ehsan Abadi, Zakaria Aboulbanine, Nicholas D Felice, David Fenwick, Anuj J. Kapadia, Cindy Marie McCabe, Jayasai Ram Rajagopal, Ehsan Samei

Affiliation: Duke University, Oak Ridge National Laboratory, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose:
Virtual imaging trials (VITs) offer a computational alternative to clinical imaging trials leveraging virtual patients, scanners, and interpreters to assess imaging questions. To provide m...

Support for Radiotherapy in Ukraine: Help Ukraine Group Activities and the Importance of International Collaboration

Authors: Serhii Brovchuk, Viktor M. Iakovenko, Nataliya Kovalchuk, Yuliia Lozko, Zoia Shepil, Natalka Suchowerska, Ruslan Zelinskyi

Affiliation: Kyiv Regional Oncology Dispensary, Stanford University, O.O. Shalimov National Institute of Surgery and Transplantology, School of Physics, The University of Sydney, Medical Physics Department, Medical center of Yuriy Spizhenko, Department of Radiation Oncology, UT Southwestern Medical Center, Stanford Cancer Center

Abstract Preview: Purpose: The full-scale russian invasion of Ukraine has caused the largest humanitarian disaster in Europe since World War II. This study identifies gaps in RT services caused by the war and outlines ...

Temporal Drift in Ir-192 Source Strength Measurements: A Braphyqs Multi-Center Analysis

Authors: Åsa K. Carlsson Tedgren, Taran Hellebust, Antonio Herreros, Jacob Johansen, Christian Kirisits, Panagiotis Papagiannis, Mark J. Rivard, Frank-Andre Siebert, Frank Verhaegen, Javier Vijande, Jan Wiersma, Marisol de Brabandere, Ruud van Leeuwen

Affiliation: UKSH, Campus Kiel, Klinik für Strahlentherapie (Radioonkologie), Department of Oncology, The Norwegian Radium Hospital, Oslo University Hospital, Radiation Physics, Department of Medicine and Health (IMH), Linköping University, Radiation Oncology Department, Hospital Clínic-Universitat de Barcelona, IDIBAPS, IFIC-UV, Radiation Oncology, Amsterdam UMC location University of Amsterdam, Department of Radiation Oncology, Radboud University Medical Center, Department of Oncology, Aarhus University Hospital, University Hospital Gasthuisberg, Dept. of Radiation Oncology, Medical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Department of Radiation Oncology (MAASTRO), GROW – School for Oncology and Reproduction, Maastricht University Medical Centre+, Department of Radiation Oncology, Comprehensive Cancer Center, Medical University of Vienna, Warren Alpert Medical School of Brown University

Abstract Preview: Purpose: This study, which was carried out by the GEC-ESTRO BRAPHYQS working group, reports the increasing divergence between clinical reference air kerma rate (RAKR) measurements and vendor-provided ...

The Comparison of Radiation Uses in Common Procedures Amongst Didactic Pediatric Fluoroscopic Units

Authors: Janet Ching-Mei Feng, Jimmy Huynh

Affiliation: UTHealth McGovern Medical School

Abstract Preview: Purpose: The Image Gently Alliance had provided helpful information to optimize image protocols in pediatric patients since 2007, and our assumption was that newer units could use near-to-optimal prot...

The Gatekeeping of Medical Physics Leading to the Underrepresentation of Black and Hispanic Women in the Field

Authors: Emily Hansen, Tyler Kaulfers, Alois M. Ndlovu, Niara Rowe, Roland Teboh

Affiliation: Montefiore Einstein University Hospital, Hackensack University Medical Center

Abstract Preview: Purpose: A topic often discussed is the disparity of women in medical physics, overlooking the absence of Black and Hispanic women in the field. The intersectionality within marginalized communities i...

Time-Efficient Photon Plan Checks with Esapi-Based Software

Authors: Kevin Peter Risolo

Affiliation: University of Pennsylvania

Abstract Preview: Purpose: To quantify the improved efficiency of checking patient treatment plan MU by utilizing RadFormation’s ClearCalc script-based program.
Methods: A total of 58 patients planned for treatment ...

Topas-Nbio – Status and Outlook after a Decade of Developments

Authors: Alejandro Bertolet, Jorge Naoki Dominguez Kondo, Bruce A. Faddegon, Kathryn D Held, Nicolas Henthorn, Jay LaVerne, Thongchai Masilela, Stephen J. McMahon, Isaac Meyer, Victor V. Onecha, Harald Paganetti, Jose A. Ramos-Mendez, Jan PO Schuemann, Wook-Geun Shin, Michael Taylor, John Warmenhoven

Affiliation: Massachusetts General Hospital, Queen's University Belfast, Massachusetts General Hospital and Harvard Medical School, University of California San Francisco, University of Manchester, Notre Dame University

Abstract Preview: Purpose: TOPAS-nBio brings a cutting-edge Monte Carlo (MC) simulation framework to the research community to test hypotheses of radiation effects at the nanometer/cell scale. Here, we present the deve...

Treatment Plan Comparisons of Head and Neck Cancers on Varian Ethos/Halcyon and Truebeam Linac

Authors: Yunfeng Cui, Joseph P. Kowalski, Qiuwen Wu, Yibo Xie

Affiliation: Duke University, Duke University Medical Center

Abstract Preview: Purpose: A Varian Ethos/Halcyon linac was recently commissioned in our clinic and was used to treat head and neck cancer patients. The purpose of this study is to compare treatment plan quality and de...

Troubleshooting respiratory motion management: Will Task Group 324 help solve my clinical challenges?

Authors: Paul J. Keall

Affiliation: Image X Institute, Faculty of Medicine and Health, The University of Sydney

Abstract Preview: N/A...

Tumor Response to Catalytic Effect of Carbamide Peroxide to Megavoltage Radiodynamic Therapy with 5-Aminolevulinic Acid

Authors: Lili Chen, Dusica Cvetkovic, Chang Ming Charlie Ma, Dae-Myoung Yang

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose: Cytotoxicity caused by the reactive oxygen species (ROS) is a mechanism for treating cancer cells in radiation therapy. 5-aminolevulinic acid (5-ALA)-mediated radiodynamic therapy (RDT), whic...

Two's Company, Three's a Crowd? a Bayesian Approach to Optimizing the Number of Measurement Readings in Radiation Therapy QA

Authors: Siyong Kim, Ava Paek, Joseph B. Schulz, James J. Sohn, Eric D. Stolen, Ethan D. Stolen

Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Central Florida, Virginia Commonwealth University, Department of Radiation and Cellular Oncology, University of Chicago, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: The American Association of Physicists in Medicine Task Group 142 (AAPM TG-142) guidelines recommend three measurements during monthly quality assurance to keep results within two standard de...

Ultrasonic Detection of Flash-Level Dose Pulses from a Medical Linac

Authors: Fred B. Bateman, Ilaria M. Luna, Ronald E. Tosh

Affiliation: Sidwell Friends School, NIST, Dosimetry Group, Radiation Physics Division, National Institute of Standards and Technology

Abstract Preview: Purpose: To exploit the rapid response time and dose sensitivity of ultrasonic detection methods for resolving pulse structure in FLASH-level beams.

Methods: Two ultrasonic transducers position...

Unsupervised Task-Specific Histology Image Stain Standardization and Crypt Detection for Evaluating Normal Tissue Flash Irradiation Response

Authors: Muhammad Ramish Ashraf, Kerriann Casey, Suparna Dutt, Jie Fu, Edward Elliot Graves, Xuejun Gu, Hao Jiang, Brianna Caroline Lau, Billy W Loo, Weiguo Lu, Rakesh Manjappa, Stavros Melemenidis, Erinn Bruno Rankin, Lawrie Skinner, Luis Armando Soto, Murat Surucu, Vignesh Viswanathan, Zi Yang, Amy Shu-Jung Yu

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine, Department of Comparative Medicine, Stanford University School of Medicine, Department of Radiation Oncology, Stanford University Cancer Center

Abstract Preview: Purpose: The intestine is a classical preclinical model for studying radiation injury, and histological quantification of intestinal crypts is a key assay for assessing this response. However, substan...

Update on Current Imaging Technologies and a Look Ahead

Authors: Ehsan Samei

Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: N/A...

Using a Generative Adversarial Network (GAN) for Source Particle Generation in Monte Carlo Radiation Therapy Simulations

Authors: Jiankui Yuan, Dandan Zheng, Tingliang Zhuang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Rochester, Varian Medical Systems, Advanced Oncology Solutions

Abstract Preview: Purpose: In Monte Carlo (MC) radiation therapy dose calculations, latent variance exists when directly applying phase-space files (PSF) with a finite number of source particles, while the latter is pr...

Weekly Changes in Ventilation Response for Photon and Proton Patients during Radiotherapy

Authors: Kristy K. Brock, Austin Castelo, Yulun He, Zhongxing Liao, Rebecca Lim, Radhe Mohan, Caleb O'Connor, Tien T Tang, Uwe Titt

Affiliation: University of Washington, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Conformal dose distributions in proton radiotherapy promise to reduce normal tissue toxicity such as radiation-induced pneumonitis, but this has not been fully realized in clinical trials. To...

What is “excessive” and “inadequate” in the new CMS rule?

Authors: Ehsan Samei

Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: N/A...