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Results for "igrt systems": 61 found

A Novel Approach to Preclinical Intensity-Modulated Radiotherapy Using an Open-Source Ring-Based Compensator Device and Inverse Treatment Planning System

Authors: Benjamin R. Awad, Bulent Aydogan, Howard J Halpern, Erik Pearson, Gage H. Redler, Jordan M. Slagowski, Rajit Tummala, Autumn E. Walter-Denzin, Jimmy Zydlo

Affiliation: University of Wisconsin-Madison Department of Human Oncology, University of Oxford, The University of Chicago, Moffitt Cancer Center, California State University, Fresno, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Small animal models are crucial in cancer research to develop, validate, and translate basic scientific hypotheses into clinical advancements. This study aims to make small animal intensity-m...

A Patient-Specific Approach to Surface Guided-DIBH SBRT Candidacy Using Surface Deformation Maps

Authors: Savannah Decker, Grace Gwe-Ya Kim, Laura Padilla

Affiliation: UC San Diego, University of California San Diego

Abstract Preview: Purpose: The success of surface-guided deep-inspiration breath-hold (SG-DIBH) treatments depends on accurate identification of suitable candidates. Sub-optimal patient selection can result in prolonge...

A Real-Time 6 Degrees-of-Freedom Image Guided Radiation Therapy Technology Using Internal-External Motion Correlation Modelling

Authors: Jeremy T. Booth, Nicholas Hardcastle, Freeman Jin, Alicja Kaczynska, Paul J. Keall, Chandrima Sengupta

Affiliation: Northern Sydney Cancer Centre, Royal North Shore Hospital, Physical Sciences, Peter MacCallum Cancer Centre, Image X Institute, Faculty of Medicine and Health, University of Sydney, Image X Institute, Faculty of Medicine and Health, The University of Sydney

Abstract Preview: Purpose: An ESTRO survey reported that 71% of radiotherapy centers across 41 countries want to implement real-time image guided radiation therapy (IGRT) to improve patient outcomes. To address this gl...

A Simple and Reliable Method to Determine Patients Eligible for Treatment on the Novel Biological Guided Radiotherapy (BgRT) System Based on FDG Uptake in Nearby Non-Treatment Regions.

Authors: Brett Lewis, Roland Teboh

Affiliation: HUMC, Hackensack University Medical Center

Abstract Preview: Purpose: The novel RefleXion SCINTIX BgRT system relies on the FDG uptake distribution from a PET study to plan and deliver dose. One of the patient eligibility criteria is that any uptake outside the...

An Automated Notification System for Identifying Patients Eligible for Biology-Guided Radiotherapy

Authors: Shahed Badiyan, Bin Cai, Tu Dan, Michael Dohopolski, Steve B. Jiang, Deepkumar Mistry, Arnold Pompos, Robert Timmerman, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Biology-guided radiotherapy (BGRT) offers significant potential for personalized and adaptive cancer treatment, with clinically available systems such as SCINTIX from Reflexion now being intr...

An Efficient Workflow for X-Ray Imaging-Based IGRT/ART

Authors: Lili Chen, Ahmed A. Eldib, Chang Ming Charlie Ma

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose: Specialized adaptive radiotherapy (ART) systems have been developed and clinically implemented, which are either cost-ineffective such as MR-linacs or inflexible in workflow such as the Ethos...

Assessing the Need for Online Adaptive Prostate SBRT Using the MR-Linac

Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Samuel Richter, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: This study evaluates the necessity and potential benefits of online adaptive stereotactic body radiotherapy (SBRT) for prostate cancer using the ViewRay MR-Linac system. By leveraging real-ti...

Assessment of the Auto Registration Feature of the PET/CT Linac Used for Biology Guided Radiation Therapy (BGRT)

Authors: Emily Hansen, Tyler Kaulfers, Alois M. Ndlovu, Francia Romero, Niara Rowe, Roland Teboh

Affiliation: Montefiore Einstein University Hospital, Hackensack University Medical Center

Abstract Preview: Purpose: Daily use and reliance on the auto registration feature requires a performance check. Clinical application of auto registration is performed without a selected region of interest (ROI), requi...

Auto-Beam Hold Validation for Varian Sgrt Identify 3.0 on Truebeam Linear Accelerators

Authors: Hongyu Jiang, Wangyao Li, Dima Soultan, Fen Wang, Jun Xu

Affiliation: Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: To validate the Auto-Beam Hold functionality via the MMI connection between Varian SGRT system IDENTIFY 3.0 and treatment linacs.
Methods: A treatment plan was created in the Eclipse TPS u...

Automation of Daily, Monthly, and Annual Image Quality Controls of Image-Guided Radiotherapy (IGRT) Systems

Authors: Alvaro Daniel Cruz Cortes, Robin Enric Lopez Fonseca, Valeria Pérez Martínez

Affiliation: National Autonomous University of Mexico (UNAM), Faculty of Sciences, Biomedical Physics Program, National Autonomous University of Mexico (UNAM), Faculty of Sciences, National Autonomous University of Mexico (UNAM), Faculty of Sciences, Physics Program

Abstract Preview: Purpose: Automate and evaluate daily, monthly, and annual QC of IGRT systems, following the AAPM TG-198 protocol, through the development of a graphical user interface that enables efficient analysis ...

Characterizing a VMAT Optimization Algorithm with Integrated Static-Angle Modulated Ports for Esophageal Cancer Treatment

Authors: Lei Dong, Yin Gao, Taoran Li, Michael Salerno, Boon-Keng Kevin Teo, Melissa Vila

Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania

Abstract Preview: Purpose: A novel solution, RapidArc Dynamic-RAD (Varian Medical Systems, Palo Alto, USA) has been implemented to integrate VMAT with modulation of IMRT-like static-angle ports, including use of a dyna...

Clinical Implementation of a Film Based Psqa System for SBRT on a 1.5T MR-Linac

Authors: Dylan Yamabe Breitkreutz, Lee Chin, Brige P. Chugh, Mark D'Souza, Brian M. Keller, Anthony Kim, Michelle K. Nielsen, Arjun Sahgal

Affiliation: Sunnybrook Health Sciences Centre

Abstract Preview: Purpose: The Elekta Unity MR-linac delivers highly conformal SBRT treatments using IMRT. These treatment plans require patient-specific quality assurance (PSQA) measurements to detect discrepancies be...

Compressed Radiotherapy Treatment Planning (CompressRTP): A New Paradigm for Rapid and High-Quality Treatment Planning Optimization

Authors: Gourav Jhanwar, Mojtaba Tefagh, Masoud Zarepisheh

Affiliation: The University of Edinburgh, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose:
Radiotherapy treatment planning involves solving computationally-intensive and time-consuming optimization problems. Central to these problems is a large matrix known as the dose-influence...

Convergence Speed Advantages of a Machine Learning Assisted Framework in IMRT Fluence Map Optimization – a Comparison Study Using Multiple Convergence Criteria

Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang

Affiliation: Duke University Medical Center

Abstract Preview: Purpose: Convergence speed is crucial for an optimizer. Faster convergence leads to better solutions with fewer iterations and less time. Recently, a machine learning (ML)-assisted framework employing...

Creation of Customized Workflows in a New Surface-Guided Radiation Therapy (SGRT) System

Authors: Sorour Hosseini, YuHuei Jessica Huang, Jeremy Kunz, Nicholas Pierre Nelson, Ryan G. Price, Prema Rassiah, Hui Zhao

Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah

Abstract Preview: Purpose: To investigate the feasibility and clinical implications of creating customized workflows in a new SGRT system: LUNA 3D (LAP, Florida).
Methods: Three clinical SGRT workflows were designed...

Developing and Evaluating the First Pre-Treatment Physics Plan Checklist for Error Detection in Biology-Guided Radiotherapy (BgRT)

Authors: Michael Burke, David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Vanessa Hill, Ann-Teresa Jasman, John Kim, Svetlana Kuznetsova, MinYoung Lee, Daniel Longo, Henry S. Park, Adam Shulman, Lauren Tressel, Weili Zhong

Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose:
The complexity of biology-guided radiotherapy (BgRT), particularly with systems like RefleXion X1, necessitates robust pre-treatment quality assurance (QA) to ensure patient safety, treatm...

Developing and Using Barcode-Reading Type Portable OCT Imaging System to Detect Surgical Margin

Authors: Dukagjin Blakaj, Zhilin Hu, Stephen Kang, Abberly Lott Limbach, Lanchun Lu, Henry Xiang, Jie Zhang

Affiliation: Pharostek, Department of Pediatrics, The Ohio State University, Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Department of Radiology, University of Kentucky, Department of Pathology, The Ohio State University, Department of Radiation Oncology, The Ohio State University, Department of Otolaryngology, The Ohio State University

Abstract Preview: Purpose: Detect surgical margin in vivo using an original barcode-reading type portable OCT imaging system.
Methods: We developed a barcode-reading type portable optical coherence tomography (OCT) ...

Development and Evaluation of Aria Report-Based Initial Chart Check Tool

Authors: Ulrich Langner, Timothy Leech, Oleksii Semeniuk

Affiliation: Brown University Health

Abstract Preview: Purpose: To standardize and improve quality of the chart review process, while simultaneously increasing the efficiency of the physicist, by allowing them to allocate more time for other items.
Met...

Development of a Beam Profile Variation Observation Model for Intensity Modulated Radiotherapy

Authors: Kaile Li

Affiliation: Alexander T. Augusta Miliary Medical Center

Abstract Preview: Purpose: To develop a experimental method in observation of beam profile transfer model in intensity modulated radiotherapy (IMRT).
Methods: A picket fence plan was generated in Eclipse treatment p...

Development of a Fast Quality Assurance Software Tool for Helical Online Adaptive Radiation Therapy

Authors: Guang-Pei Chen, Mi Huang, Haidy G. Nasief, Eric S. Paulson

Affiliation: Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Recently, kV imaging has been integrated into the Accuray Radixact platform, facilitating online adaptive and scan-plan-treat workflows with helical delivery in the near future. In order to s...

Developments of a Low-Cost Multi-Target Winston-Lutz Phantom and Software for SRS Linac Machines

Authors: Nellie Brovold, Wenbo Gu, Huan Amanda Liu, Lin Ma

Affiliation: University of Pennsylvania, Mayo Clinic

Abstract Preview: Purpose: To develop a low-cost comprehensive QA phantom and software for single-iso multi-target SRS Linac machines. This phantom can perform 1) Winston-Lutz QA test for on-axis and off-axis targets, ...

Diffusion-Based PET Image Enhancement in Bgrt

Authors: David J. Carlson, Huixiao Chen, Tianqi Chen, Jun Hou, Chi Liu, Qiong Liu, Henry S. Park, Huidong Xie

Affiliation: Yale University, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose:
The RefleXion® X1 Biology-guided radiotherapy (BgRT) system consists of dual PET detectors, a 6MV linear accelerator (linac), a 64-leaf collimator, an MVD detector, and a CT scanner mounte...

Dosimetric Assessment of Spatially Fractionated Radiation Therapy on Prostate Cancer Cases: Our Experience in Nsia-Luth Cancer Center, Lagos

Authors: Adebayo Abe, Samuel Olaolu Adeneye, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Sylvester Entonu, Muhammad Habeebu, Adedayo O. Joseph, Oluwaseyi Oderinde, Oluwadara Ojediran, Margaret Dideolu Taiwo

Affiliation: University of Ibadan, University of Lagos, Missouri University of Science and Technology, Purdue University, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre

Abstract Preview: Purpose:
Spatially Fractionated Radiation Therapy (SFRT) is an advanced radiotherapy technique designed to deliver highly heterogeneous radiation doses, aiming to optimize tumor control while minim...

Dosimetric Evaluation of Radiation Treatment Planning Algorithms in IMRT and VMAT Techniques: Analysis with Central and Peripheral Lung Tumors

Authors: Sumanta Manna, Atul Mishra, Surendra Prasad Mishra, Kailash Kumar Mittal, Anoop Kumar Srivastava, Neha Yadav

Affiliation: Department of Radiation Oncology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Department of radiation Oncology, Apollomedics Super Speciality Hospitals, Department of Radiation Oncology, Uttar Pradesh University of Medical Sciences, Department of Radiation Oncology, Kalyan Singh Super Specialty Cancer Institute

Abstract Preview: Purpose: This study aimed to assess the dosimetric performance of Volumetric Modulated Arc Therapy (VMAT), step-and-shoot Intensity-Modulated Radiation Therapy (ss-IMRT), and dynamic Intensity-Modulat...

Dosimetric Impact of Target Coverage with Inter-Fraction Patient Yaw Setup Error in IMRT/VMAT Prostate Cancer Radiotherapy

Authors: Min Su

Affiliation: Mount Sinai School of Medicine

Abstract Preview: Purpose: To evaluate dosimetric impact of patient setup yaw error to target coverage for pelvis/prostate radiation external beam IMRT-VMAT treatment.
Methods: 9 Pelvis/prostate IMRT-VMAT treatment ...

Efficient FAST-Forward Planning Strategy for X-Ray Based Online Adaptive Radiotherapy

Authors: Prasanna Alluri, Mona Arbab, Xingzhe Li, Chang-Shiun Lin, Mu-han Lin, David D.M. Parsons, Asal Rahimi, Justin D. Visak, Narine Wandrey

Affiliation: UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX

Abstract Preview: Purpose: Intelligence-Optimization-Engine (IOE) v1.0 relied heavily on planner expertise and patient-specific IMRT beam arrangements, requiring frequent revisions. While VMAT workflows offered potenti...

Empowering Radiation Oncology in Sudan with Virtual and Augmented Reality Solutions

Authors: Abdelfatah Abdalla Nemer Abdelsalam, Elmubarak M. Ahmed, Sarah A. Ashmeg, M. Saiful Huq, Alsadeg Awad Alamin Mohamed, Ali Sid Ahmed Mohammed, Christopher Tyerech

Affiliation: UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, UPMC Hillman Cancer Center, University of Medical Science and Technology, King Abdulaziz Medical City, Department of Radiation Oncology, University of Pennsylvania, Tumor Therapy and Cancer Research Center, Al Neelain University

Abstract Preview: Purpose: Severe conflict in Sudan has led to the closure of several cancer services within the country. With new centers in development by an IAEA and Rays of Hope initiative, many barriers exist in m...

Enhancing Medical Physics Education: From Student Needs to a Moodle-Based LMS

Authors: Paul B. Ravindran

Affiliation: Christian Institute of Health Sciences and Research

Abstract Preview: Purpose: In the past decades, Master's programs in Medical Physics in India have made significant strides, though many have faced challenges in accessing adequate resources for didactic lectures and p...

Establishing Comprehensive QA for Single-Isocenter Multiple Targets Stereotactic Radiosurgery

Authors: Angel Gomez, Titania Juang, Grace Gwe-Ya Kim, Boyu Meng

Affiliation: UC San Diego, UCSD, University of California San Diego

Abstract Preview: Purpose: Single-Isocenter Multiple Targets (SIMT) Stereotactic Radiosurgery (SRS) is widely used for its precision and effectiveness. However, standardized quality assurance (QA) protocols for SIMT SR...

Establishing Tumor Size-Dependent Contrast Requirements for Multi-Target Biology-Guided Radiation Therapy (BgRT)

Authors: Muhammad Ramish Ashraf, Girish Bal, Daniel Pham, Murat Surucu

Affiliation: RefleXion Medical, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University

Abstract Preview: Purpose: To determine minimum target size and FDG contrast thresholds for reliable Biology-guided Radiation Therapy (BgRT) delivery using a systematic phantom study.
Methods: A custom 3D-printed ph...

Evaluating Planning Metrics for Biology-Guided Radiation Therapy (BgRT)

Authors: Emily Hansen, Jay Mistry, Alois M. Ndlovu, Niara Rowe, Roland Teboh

Affiliation: Hackensack University Medical Center

Abstract Preview: Purpose: SCINTIX Biology-guided radiotherapy (BgRT) on the RefleXion X1 relies on a new planning system and advanced planning techniques. The first patient SCINTIX BgRT plans are compared to similar c...

Evaluation of AI-Generated Synthetic 4DCT from 3DCT for Radiotherapy Planning

Authors: Shinichiro Mori, Isabella Pfeiffer, Chester R. Ramsey, Alexander Usynin

Affiliation: Thompson Proton Center, National Institutes for Quantum Science and Technology, Thompson Cancer Survival Center

Abstract Preview: Purpose: Four-dimensional CT imaging (4DCT) has become a standard tool for managing respiratory motion in radiation therapy. However, many treatment delivery systems and most diagnostic CT scanners la...

Evaluation of Time Delays in a Surface-Guided Radiotherapy-Based Gating System Using Exactrac Dynamic and Truebeam Linear Accelerator

Authors: Hiroki Katayama, Hiroki Kawasaki, Motonori Kitaoka, Yosuke Takahashi, Takashi Tanii, Masato Tsuzuki

Affiliation: Kagawa University Hospital

Abstract Preview: Purpose:
Surface-guided radiotherapy (SGRT) with ExacTrac Dynamic (ETD) allows motion tracking and beam gating during treatment delivery. Accurate evaluation of beam-on and beam-off delays is essen...

Evaluation of a Commercial Metal Artifact Reduction Algorithm for IGRT in Patients with Hip Prostheses

Authors: Laura Bennett, Matthew Charles, Greg Cooley, John M. Floberg, Ryan Hutten, Elissa Khoudary, Nicholas Lynch, Kaili Ranta, Jordan M. Slagowski, Trevor Wilson

Affiliation: University of Pennsylvania, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, University of Wisconsin-Madison, University of Wisconsin-Madison

Abstract Preview: Purpose: To evaluate the impact of an iterative cone beam CT with metal artifact reduction (iCBCT+MAR) reconstruction algorithm (HyperSight TrueBeam 4.1, Varian Medical Systems) on image quality and s...

Evaluation of the Imaging Performance of PET-Linac As Compared to a Diagnostic PET/CT System for Small Tumors

Authors: Muhammad Ramish Ashraf, Girish Bal, Daniel Pham, Murat Surucu

Affiliation: RefleXion Medical, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University

Abstract Preview: Purpose: To systematically evaluate the relationship between Activity Concentration (AC) obtained from the RefleXion PET-Linac with the maximum standardized uptake value (SUVmax) derived from a diagno...

Evaluation of the Varian Truebeam Linac Matching Process: Before, during, and after the Commission

Authors: Edwin Quashie, Yun Wang

Affiliation: Indiana University Medical School, Indiana University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose: To provide a formal evaluation for the TrueBeam linac matching process before, during and after the commission of the newly installed TrueBeam linac which we want to match to an existing True...

Failure Mode and Effects Analysis (FMEA) on Use of Surface Guided Imaging

Authors: Victoria Noelle Bry, Tamara Egan, Eric C. Ford, Angelia Landers, Juergen Meyer

Affiliation: Fred Hutch Cancer Center, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington

Abstract Preview: Purpose: Surface guided radiation therapy (SGRT) can improve patient safety, however, its complex integration may expose processes to increased risk of error. This work identifies potential failures f...

Feasibility Study of Ethos Artificial-Intelligence Online Adaptive Prostate SBRT

Authors: Miguel Albaladejo, Ana Corbalan, Aitor Ortega, Vicente Puchades, David Ramos, Alfredo Serna-Berna, Jonattan Suarez

Affiliation: Hospital General Universitario Santa Lucia

Abstract Preview: Purpose:
Prostate SBRT treatments are frequently delivered using standard VMAT IGRT technique. The aim of this study is to test the feasibility of Ethos Artificial Intelligence (AI) prostate SBRT b...

Feasibility of Using 68ga-PSMA for Biology-Guided Radiotherapy (BgRT) Treatment

Authors: Girish Bal, Thomas I. Banks, Bin Cai, Neil Desai, Aurelie Garant, Orhan Oz, Elizeva Phillips, Rameshwar Prasad, Chenyang Shen, Robert Timmerman

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical

Abstract Preview: Purpose: This study reports findings from the first-in-human imaging-only trial evaluating the feasibility of using the novel PET tracer 68Ga-PSMA-11 (Illuccix) to guide external beam radiotherapy on ...

First Phantom Testing of Biology-Guided Radiotherapy for Sequential Integrated Boost Radiotherapy

Authors: Girish Bal, David J. Carlson, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Henry S. Park

Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: This study explores the feasibility, accuracy, and dosimetric performance of hybrid biology-guided radiotherapy (BgRT) combined with image-guided radiotherapy (IGRT) for delivering sequential...

Free-Breathing VMAT and IMRT Versus Deep Inspiration Breath- Hold 3D-CRT Techniques for Left-Breast Cancer: A Practical Solution for Developing Countries

Authors: Md. Yousuf Ali, Parvin Akhter Banu, Ehteshamul Hoque, Qazi Mushtaq Hussain, Md Jobairul Islam, Md. Abdul Mannan, Sadia Afrin Sarah, Mostafa Aziz Sumon, Ahammad Al Mamun Sweet, AFM Kamal Uddin

Affiliation: Labaid Cancer Hospital & Superspeciality Centre

Abstract Preview: Purpose: Radiotherapy for left-sided breast cancer can induce cardiac injury. Deep Inspiration Breath Hold (DIBH) is a technique that minimizes cardiac exposure during treatment. This study compares d...

Implementation of a Virtual Quality Assurance System Using Raystation for Online MR-Linac Adaptive Radiotherapy

Authors: Min-Sig Hwang, Danny K. Lee, Daniel C. Pavord, Kyung Lim Yun

Affiliation: Allegheny Health Network

Abstract Preview: Purpose: Ensuring the quality of treatment plans through patient-specific pre-treatment quality assurance (QA) is essential. However, the use of physical phantom-based QA devices is not feasible for o...

Isocenter Stability after Commissioning of Biology-Guided Radiotherapy (BgRT)

Authors: Emily Hansen, Alois M. Ndlovu, Niara Rowe, Roland Teboh

Affiliation: Hackensack University Medical Center

Abstract Preview: Purpose: The accuracy of SCINTIX biology-guided radiotherapy (BgRT) on the RefleXion X1 is dependent on the correct alignment of the isocenter between all subsystems, including setup lasers, kV imagin...

Large Language Model-Driven Agentic System for Collaborative Decision-Making in Radiotherapy Treatment Planning

Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang

Affiliation: Duke University Medical Center

Abstract Preview: Purpose:
This study aims to leverage large language model (LLMs) to develop a human-in-the-loop agentic framework, enhancing the efficiency of treatment planning in radiotherapy.
Methods:
A L...

Mask-Less Adaptable Headrest for Head-and-Neck Radiotherapy

Authors: Alyssa Capizzi, John J Dombrowski, Nabil N. Khater

Affiliation: Saint Louis University

Abstract Preview: Purpose: To evaluate a mask-less adaptable headrest (MAHR) prototype for head-and-neck IMRT designed to reduce random and systematic shifts of patients’ setups. MAHR complements current image-guidance...

Maximizing Integrated Treatment Planning Tools to Increase Automation for X-Ray-Based Adaptive Lung Sabr

Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, David D.M. Parsons, Justin D. Visak, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX

Abstract Preview: Purpose: Adaptive radiotherapy (ART) programs are resource-intensive due to their technical complexities, requiring highly skilled planners. Leveraging integrated automated treatment planning system (...

Moving Away from Measuring Everything - Implementing 3D Recalculation in a Large Networked Radiotherapy Institution to Replace Routine IMRT / VMAT QA

Authors: Eujin Chan, Christopher Colyer, Leon F Dunn, Jonathan Dunning, Michael Grace, Onno Kamst, Alex Livingstone, Thulani Nyathi, Vladimir Sashin, Philip Satory, Hilmar Schachenmayr, Brindha Subramanian, Lindsay J. Tremethick, Luke Webb

Affiliation: GenesisCare

Abstract Preview: Purpose: The purpose of this work is to outline the methodology and results from the implementation of a 3D recalculation software to replace IMRT/VMAT PSQA measurement across a large, networked radio...

One Year Experience of Biology-Guided Radiotherapy (BgRT) on PET-Linac in an Academic Center

Authors: Shahed Badiyan, Girish Bal, Thomas I. Banks, Bin Cai, Tu Dan, Aurelie Garant, Andrew R. Godley, Steve Jiang, Orhan Oz, Arnold Pompos, Rameshwar Prasad, Chenyang Shen, David Sher, Robert Timmerman, Kenneth Westover

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical

Abstract Preview: Purpose: Biology-guided radiotherapy (BgRT) is a novel FDA-cleared technology for treating lung and bone tumors based on 18F-FDG PET uptake. This study summarizes the first-year experience treating 29...

Patient-Specific Treatment Plan Optimization through Intentional Deep Overfit Learning As a Warm Start for Longitudinal Adaptive Radiotherapy

Authors: Wouter Crijns, Frederik Maes, Loes Vandenbroucke, Liesbeth Vandewinckele

Affiliation: Department of Oncology, Laboratory of Experimental Radiotherapy, KU Leuven; Department of Radiation Oncology, UZ Leuven, Department ESAT/PSI, KU Leuven; Medical Imaging Research Center, UZ Leuven, Department of Oncology, Laboratory of Experimental Radiotherapy, KU Leuven

Abstract Preview: Purpose: To explore intentional deep overfit learning (IDOL) to exploit the initial treatment plan to predict an adaptive radiotherapy plan.
Methods: A conditional generative adversarial network is...

Phantom Assessment for Treating Large Tumors with Biology-Guided Radiotherapy (BgRT)

Authors: Jon Burns, Angela J Da Silva, Andrew Groll, Gopinath Kuduvalli, Manoj Narayanan, Jeffrey Schmall, Sanchit Sharma, Timothy Pok Chi Yeung

Affiliation: Reflexion Medical Inc,, RefleXion Medical

Abstract Preview: Purpose: Biology-guided radiotherapy uses positron emissions from FDG-avid tumor volumes to provide a of the planned prescribed dose with high accuracy. The purpose of this work is to characterize BgR...

Portpy: An Open-Source Python Package to Accelerate Research in Radiotherapy Treatment Planning Optimization

Authors: Qijie Huang, Gourav Jhanwar, Saad Nadeem, Vicki Trier Taasti, Mojtaba Tefagh, Seppo Tuomaala, Masoud Zarepisheh

Affiliation: Varian Medical Systems Inc, Department of Clinical Medicine - Danish Center for Particle Therapy, Aarhus University Hospital, Memorial Sloan Kettering Cancer Center, The University of Edinburgh

Abstract Preview: Purpose:
We have developed PortPy (Planning and Optimization for Radiation Therapy in Python), a first-of-its-kind open-source package designed to accelerate research and development in radiotherap...

Python-Based Patient Coaching System for Gated Treatment Delivery

Authors: Usha Robins Abraham, Monique Lockhart Chisem, Alonso N. Gutierrez, Janos Juhasz, Michael Leyva, Carlos M. Rivera, Ranjini P. Tolakanahalli, Vanessa Vega Fleites

Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute, Miami Cancer Institute, Baptist Health

Abstract Preview: Purpose:
Accurate breath hold (BH) gated treatments rely heavily on patient cooperation. Maintaining consistent breath-hold levels can be challenging for patients. Surface image guidance (SGRT) is ...

Quantification of Global Dosimetry Audit Performance: Assessing the Sensitivity and Specificity of Dosimetry Audits to Establish Reciprocity Among Different International Clinical Trials Credentialing Organizations

Authors: Fre'Etta Brooks, Catharine H Clark, Patricia Diez, Peter B. Greer, Hideaki Hirashima, Rebecca M. Howell, Mohammad Hussein, Stephen F. Kry, Joerg Lehmann, Jessica Lye, Mitsuhiro Nakamura, Christopher L. Nelson, Rushil Patel, Christine Peterson, Julianne M. Pollard-Larkin

Affiliation: Kyoto University, The University of Texas MD Anderson Cancer Center, Radiotherapy Trials Quality Assurance Group, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Medical Physics & Biomedical Engineering, University College London, Metrology for Medical Physics, National Physical Laboratory, Austin Health, University of Washington Medical Center, University of Newcastle

Abstract Preview: Purpose: To assess the consistency of end-to-end dosimetry audits currently used by different international clinical trial QA organizations with the goal of harmonizing audits and reducing audit overl...

Rectangular Aperture-Based Beam Orientation Optimization for 4π Non-Coplanar Small Animal IMRT Delivery

Authors: Dante PI Capaldi, Lu Jiang, Qihui Lyu, Ke Sheng

Affiliation: Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose:
Preclinical small animal studies help understand radiation-induced biological responses, toxicities, and mechanisms, facilitating the translation of new therapies to patient treatment. Int...

Retrospective Study Using Avi Planner for Head and Neck Cancer Cases: Our Experience at Nsia-Luth Cancer Center, South - West Nigeria

Authors: Adebayo Abe, Samuel Olaolu Adeneye, Eben Aje, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Lilian Ekpo, Muhammad Habeebu, Adedayo O. Joseph, Charles S. Mayo, Noah Ndianaobong, Ikechi S Ozoemelam, Margaret Dideolu Taiwo, Godwin Uwagba

Affiliation: University of Michigan, University of Ibadan, University of Lagos, Missouri University of Science and Technology, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre, NSIA-LUTH Cancer Center

Abstract Preview: Purpose:
Head and neck cancers (HNC) present significant challenges in radiotherapy due to complex anatomy and the proximity to critical organs at risk (OARs). These challenges are compounded in na...

Streamlined Calibration of Mosfet Dosimeters for Radixact Systems: Addressing Angular Dependence and Beam Profile Challenges

Authors: Guang-Pei Chen, Renae Conlin, Juan A. Garcia-Alvarez, Kirk Morris, Haidy G. Nasief, Eenas A. Omari, Eric S. Paulson

Affiliation: Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Cumulative dose limits make replacing and calibrating Metal Oxide Semiconductor Field Effect dosimeters (MOSFET-d) used for in-vivo dosimetry a common clinical task. Calibration protocols for...

Tackling the Challenge of Multi-Target Metastases Treatment: Evaluation of Ethos Treatment Planning System

Authors: Avery Antes, Bulent Aydogan, Rama Chicfeh, Erik Pearson, Neslihan Sarigul

Affiliation: The University Of Chicago, The University of Chicago

Abstract Preview: Purpose: This study evaluates the performance of the Ethos Treatment Planning System (TPS) in managing oligometastatic cancer patients previously treated using multiple isocenter plans.
Methods: Th...

Towards Arbitrary Phantom Patient Specific IMRT QA on Reflexion X1

Authors: Andrew Groll, Ayan Mitra, PhD, Manoj Narayanan, Sanchit Sharma, Ray Yang, Timothy Pok Chi Yeung

Affiliation: Reflexion Medical Inc,, RefleXion Medical

Abstract Preview: Purpose: To develop a versatile QA tool enabling dose recalculation of a patient’s plan sinogram redeployed onto arbitrary replacement phantom geometry, and extract computed dose along detector planes...

Unlocking Adaptive Radiotherapy Flexibility: Integrating Ethos Adaptive Therapy and Halcyon IGRT with Scripting Innovations

Authors: Min Geon Choi, Sean J. Domal, Ruiqi Li, Taoran Li, Mu-Han Lin, Yang Kyun Park, David D.M. Parsons, Justin D. Visak

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, University of Pennsylvania, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Ethos X-ray-guided online adaptive radiotherapy (ART) enables precise, daily adaptive treatments but requires significant resources, limiting widespread adoption. Many treatment sites do not ...

Using a Generative Adversarial Network (GAN) for Source Particle Generation in Monte Carlo Radiation Therapy Simulations

Authors: Jiankui Yuan, Dandan Zheng, Tingliang Zhuang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Rochester, Varian Medical Systems, Advanced Oncology Solutions

Abstract Preview: Purpose: In Monte Carlo (MC) radiation therapy dose calculations, latent variance exists when directly applying phase-space files (PSF) with a finite number of source particles, while the latter is pr...

Variations in Radiation Isocenter Offsets from the Winston-Lutz Test Performed on Different Photon Energies

Authors: Cambridge L Bui-Nguyen, Alexander S. Nguyen, Liqiang (Lee) Tao

Affiliation: Varian AOS @Epic Care, UC Berkeley

Abstract Preview: Purpose: To quantity variations in Winston Lutz (WL) test results due to different energies used in SBRT, SRT or SRS.
Methods: A WL phantom with a 6.4 mm diameter center radio-opaque sphere is used...