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Results for "immunologically cold": 2 found

BEST IN PHYSICS THERAPY: Immunomodulatory Effects of Selective PARP1 Inhibition in Combination with Photon and Alpha Particle Therapy in Immunologically Cold Breast Cancer

Authors: Scott James Bright, Vered Domankevich-Bachar, Mandira Manandhar, Poliana Marinello, Yogesh Rai, Marco Freitas Reis, Alexandre Rubinstein, Gabriel O. Sawakuchi, Ronen Segal, Walison Augusto Silva Brito, Mark Wasley, Amy Wu

Affiliation: MD Anderson Cancer Center, Alpha Tau Medical Ltd, Alpha Tau Medical LTD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Immunologically cold breast cancers are aggressive and difficult to treat due to their lack of immune cell infiltration. The combination of high-LET radiation with DNA repair inhibitors offer...

Radio-Immune Response Model for the Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR)

Authors: Young-Bin Cho, Robert Timmerman

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Cleveland Clinic

Abstract Preview: Purpose: Immunologically hot (MC38) and cold (LLC) tumor in mouse were treated with radiation and/or immunotherapy agent for the study of Personalized Ultrafractionated Stereotactic Adaptive Radiother...