Authors: Yasin Abdulkadir, Justin Hink, James M. Lamb, Jack Neylon
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: Curation remains a significant barrier to the use of ‘big data’ radiotherapy planning databases of 100,000 patients or more. Anatomic site of treatment is an important stratification for almo...
Authors: Yan Chu, Madison Emily Grayson, Radhe Mohan, Pablo P. Yepes
Affiliation: UT Health Science Center at Houston, Rice University, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Radiation-induced lymphopenia (RIL) is a common adverse effect of radiation therapy, negatively impacting overall survival and anti-PD1 immunotherapy efficacy. Our lab previously developed a ...
Authors: Sahaja Acharya, Matthew Ladra, Junghoon Lee, Lina Mekki, Bohua Wan
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University, Department of Computer Science, Johns Hopkins University
Abstract Preview: Purpose: Cerebellar mutism syndrome (CMS) is the most frequently observed complication in children undergoing surgical resection of posterior fossa tumors. Previous work explored lesion to symptom map...
Authors: Weikang Ai, Xiaoyu Hu, Xun Jia, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Department of Biomedical Engineering, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Real-time tumor tracking is critically important for respiratory motion management for lung cancer radiotherapy. A previously proposed application of a photon counting detector involves measu...
Authors: John Ford, Yu Fujiwara, Isao Murata, Zavier Ndum Ndum
Affiliation: Osaka University, Texas A&M University
Abstract Preview: Purpose: This study investigates how particle energy affects radiation quality and biological effectiveness with the inclusion of medical implants. Our research group used microdosimetric analysis to ...
Authors: Ruth Afanador, Daniela Branco, John M Bryant, John Campbell, Clement Chaphuka, Samuel A. Einstein, David B. Flint, Jeffrey R. Kemp, Mussa Kumwembe, Daniel J Mollura, Joseph Weygand
Affiliation: RAD-AID International, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, UNC Health, Malawi National Cancer Center, Kamuzu Central Hospital, Penn State College of Medicine, Sutter Health, New York University, University of California San Diego / California Protons, Department of Radiation Oncology, Moffitt Cancer Center
Abstract Preview: Purpose: Malawi, a landlocked country in southeastern Africa with a population of over 20 million, ranks among the world’s least-developed nations and has the fourth-lowest gross domestic product per ...
Authors: Brian D. Casto, Mathew Y Kang, Lichung Ku, Samuel J Wang, Joseph B. Ying, Walker Ray Zimmerman
Affiliation: Salem Health Cancer Center, Salem Health
Abstract Preview: Purpose: Varian HyperArc is an advanced radiotherapy module designed to efficiently deliver high-quality multi-target stereotactic radiosurgery (SRS) treatment plans on Varian linacs. However, the int...
Authors: Junghoon Lee, Todd R. McNutt, Harry Quon, Bohua Wan
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, Department of Computer Science, Johns Hopkins University
Abstract Preview: Purpose: Xerostomia is a common toxicity in head and neck cancer (HNC) radiotherapy (RT). A few deep learning (DL) models have been proposed to predict the chance of xerostomia 12 months after RT with...
Authors: Resat Aydin, Joseph Barbiere, Brett Lewis, Roland Teboh
Affiliation: HUMC, Hackensack University Medical Center
Abstract Preview: Purpose:
Accurately compensating for respiratory-induced tumor motion is critical in BgRT, where precise delineation of volumes ensures effective dose delivery. We propose an integrated approach th...
Authors: William N. Duggar, Amirhossein Eskorouchi, Haifeng Wang
Affiliation: Mississippi State University, University of Mississippi Medical Center
Abstract Preview: Purpose:
Extracapsular extension (ECE) in lymph nodes represents a critical prognostic factor in head and neck squamous cell carcinoma (HNSCC), bearing important implications for staging, treatment...
Authors: Rachel B. Ger, Xun Jia, Youfang Lai, Todd R. McNutt, Xingyi Zhao
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Radiotherapy (RT) plays an essential role for head and neck (HN) cancer treatment but often results in xerostomia due to salivary gland damage. It is important to mechanistically model the ra...
Authors: Gregory Bolard, Rabten Datsang, Sarah Ghandour, Timo Kiljunen, Pauliina Paavilainen, Sami Suilamo, Katlin Tiigi
Affiliation: Turku University Hospital, Virginia Commonwealth University, MVision AI, North Estonia Medical Centre, Docrates Cancer Center, Hopital Riviera-Chablais
Abstract Preview: Purpose: To verify the performance of a vendor-neutral deep learning model for synthetic CT generation from T2-weighted and balanced steady-state MR sequences to support both MR-only simulation and MR...
Authors: Go Akamatsu, Han Gyu Kang, Chie Seki, Hitomi Sudo, Hideaki Tashima, Chie Toramatsu, Hidekatsu Wakizaka, Iwao Yamaya, Taiga Yamaya
Affiliation: National Institutes for Quantum Science and Technology
Abstract Preview: Purpose:
Tumor oxygen status, which provides important information to optimize particle therapy, may constantly change during a treatment period of several weeks. However, it is impractical to perf...
Authors: Cem Altunbas, Adam Avant, Farhang Bayat, Roy Bliley, Ian Boor, Brian Kavanagh, Uttam Pyakurel, Tyler Robin, Ryan Sabounchi
Affiliation: Department of Radiation Oncology, University of Colorado School of Medicine, Taussig Cancer Center, Cleveland Clinic
Abstract Preview: Purpose: Improved soft tissue visualization plays an important role in target localization and treatment plan adaptation in CBCT-guided radiotherapy. In this work, a novel CBCT approach, 2D antiscatte...