Authors: Gabriel Lucas Andrade de Sousa, Einsley-Marie Janowski, Cam Nguyen, Krishni Wijesooriya
Affiliation: Department of Radiation Oncology, University of Virginia, Department of Physics, University of Virginia
Abstract Preview: Purpose: Optimizing radiation therapy (RT) to spare the immune system may improve Overall Survival (OS) in cancer patients. This study develops a computational algorithm to identify optimal dose-volum...
Authors: Dale Black, David Clymer, Huanjun Ding, Hamidreza Khodajou Chokami, Sabee Molloi, Christine Vy Nguyen, Tim Sananikone, Alireza Shojazadeh, Randy Wang
Affiliation: Department of Radiological Sciences, University of California, University of California, Department of Radiological Sciences, University of California, Irvine, Department of Radiological Sciences, University of California, Irvine
Abstract Preview: Purpose: We present a novel multi-material decomposition (MMD) algorithm for accurate quantification of material concentration in reconstructed dual-energy CT images. This method addresses limitations...
Authors: Christopher L. Deufel, Suman Gautam, William Y. Song
Affiliation: Virginia Commonwealth University, Mayo Clinic
Abstract Preview: Purpose: Direction modulated brachytherapy creates anisotropic dose distribution from an isotropic source. This study aims to develop a truncated conditional value at risk optimization algorithm for D...
Authors: Lei Xing, Zixia Zhou
Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Stanford University, Stanford
Abstract Preview: Purpose: Functional brain imaging techniques, such as functional magnetic resonance imaging (fMRI), generate high-dimensional, dynamic data reflecting complex neural processes. However, extracting rob...
Authors: Yabo Fu, Yang Lei, Yu Lei, Haibo Lin, Ruirui Liu, Tian Liu, Kenneth Rosenzweig, Charles B. Simone, Shouyi Wei, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York Proton Center
Abstract Preview: Purpose: Beam orientation optimization (BOO) in intensity-modulated radiation therapy (IMRT) is traditionally a complex, non-convex problem tackled with heuristic methods. This study benchmarks global...
Authors: Xu Chen, Jun Lian, Yunkui Pang, Pew-Thian Yap
Affiliation: University of North Carolina at Chapel Hill, Huaqiao University
Abstract Preview: Purpose: Unsupervised CBCT-to-CT translation in the pelvic region is essential for accurate radiotherapy delivery and adaptive image-guided interventions. However, current models for cross-modality tr...
Authors: Jacob Gooslin, Ellis Lee Johnson, Damodar Pokhrel
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: HyperArc radiosurgery permits treatment of multiple brain lesions using a single-isocenter improving treatment planning efficiency and workflow. A key stereotactic planning aspect is an indep...
Authors: Somayeh Gholami, Saeedeh Ketabi, Jeremy Kunz, Ali Yousefi
Affiliation: Department of Radiation Oncology, University of Utah, University of Utah, Department of Management- Operations Research, University of Isfahan
Abstract Preview: Purpose: This paper aims to present a novel approach for automatic knowledge-based planning optimization for Intensity Modulated Radiotherapy, along with the two downsizing techniques for improving th...
Authors: Robert A. Corns, Mohammad Kanber
Affiliation: East Carolina University, East Carolina University Brody School of Medicine
Abstract Preview: Purpose:
Accurate determination of the radiation isocenter is crucial for precise radiotherapy treatments, directly impacting patient safety and treatment quality. This study presents a computation...
Authors: Girish Bal, Jan Kralj, Ayan Mitra, PhD, Ling Shao, Matjaz Subic, Yevgen Voronenko
Affiliation: RefleXion Medical, Cosylab
Abstract Preview: Purpose: This work enhances the efficiency of radiation therapy treatment planning by optimizing the beamlet dose matrix and full patient dose computations using GPU acceleration. The Collapsed-Cone C...
Authors: Ara Alexandrian, Sadiki Daniel
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: To develop a learning-to-optimize machine learning model that accelerates optimization in VMAT treatment planning by training on prostate patient data.
Methods: A treatment plan dataset of...
Authors: Daisuke Kawahara, Yoichi Watanabe
Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Radiation Oncology, University of Minnesota Medical School
Abstract Preview: Purpose: Combination therapies with immunotherapy (IT) and radiotherapy (RT) are widely used, but the optimal IT timing is unclear. This study leverages a computational cellular automaton (CA) model, ...
Authors: Xuezhen Feng, Li-Sheng Geng, Haoze Li, Xi Liu, Tianyu Xiong, Ruijie Yang
Affiliation: Department of Health Technology and Informatics, The Hong Kong Polytechnic University, School of Physics, Beihang University, School of Nuclear Science and Technology, University of South China, Department of Radiation Oncology, Peking University Third Hospital
Abstract Preview: Purpose: This study aimed to develop a deep learning-based algorithm for automatically delineate gross tumor volume (GTV) for lung cancer patients, alleviating the workload of radiologists and improvi...
Authors: Zayne Belal, Rachel Drummey, Clifton David Fuller, Stephen Y. Lai, Brigid A. McDonald, Setareh Sharafi, Sonja Stieb, Kareem Abdul Wahid
Affiliation: Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, Hospital of the University of Pennsylvania, Department of Radiology, Johns Hopkins University, KSA-KSB, Cantonal Hospital Aarau, College Of Osteopathic Medicine, NOVA Southeastern University, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose:
Radiotherapy-induced dysphagia can significantly impair head and neck (H&N) cancer patients’ quality of life. Despite the dose-dependent relationship between radiotherapy and dysphagia, sw...
Authors: Yizheng Chen, Md Tauhidul Islam, Mingjie Li, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose:
Biomedical image segmentation (BIS) is a cornerstone of medical physics, enabling accurate delineation of anatomical structures and abnormalities, which is critical for diagnosis, treatmen...
Authors: Bryan Bednarz, Larry A. DeWerd, Sean Jollota, Ahtesham Ullah Khan, Ohyun Kwon, Jeff Radtke
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison
Abstract Preview: Purpose: The accurate quantification of absorbed dose is essential for alpha-emitting radionuclides used in radiopharmaceutical therapy (RPT). This study presents the first direct comparison of physic...