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Results for "inverse optimized": 10 found

A Novel Approach to Preclinical Intensity-Modulated Radiotherapy Using an Open-Source Ring-Based Compensator Device and Inverse Treatment Planning System

Authors: Benjamin R. Awad, Bulent Aydogan, Howard J Halpern, Erik Pearson, Gage H. Redler, Jordan M. Slagowski, Rajit Tummala, Autumn E. Walter-Denzin, Jimmy Zydlo

Affiliation: University of Wisconsin-Madison Department of Human Oncology, University of Oxford, The University of Chicago, Moffitt Cancer Center, California State University, Fresno, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Small animal models are crucial in cancer research to develop, validate, and translate basic scientific hypotheses into clinical advancements. This study aims to make small animal intensity-m...

AI-Assisted Algorithm to Generate Patient Postures for Tset Dose Evaluation

Authors: Kostas Danniidis, Agelos Kratimenos, Yufu Wang, Timothy C. Zhu, Yifeng Zhu

Affiliation: University of Pennsylvania

Abstract Preview: Purpose: This study aims to develop software and algorithms utilizing artificial intelligence (AI) to seamlessly create 3D patient postures during Total Skin Electron Therapy (TSET). The resulting mes...

Adapting Newer Treatment Planning Strategy for Uveal Melanoma Cases Using Gamma Knife Radiosurgery

Authors: Deepak Agrawal, Subhash Gupta, Shashanksharad Kale, Gopishankar Natanasabapathi, Manoj Phalak, Dhanabalan Rajasekaran, Surendra Kumar Saini, Subramani Vellaiyan

Affiliation: All India Institute of Medical Sciences (AIIMS), All India Institute of Medical Sciences

Abstract Preview: Purpose:
To evaluate planning strategy for uveal melanoma tumor (UM) in gamma knife stereotactic radiosurgery (GKSRS) using Lightning inverse planning software for treatment planning.
Methods:

An Integrated Robust Inverse Planning Based on AI-Built Dose Kernel Library for Preclinical Radio-Neuromodulation Using Focused Kv X-Rays

Authors: Wenbo Gu, Chenhui Qiu, Ke Sheng, Liyan Sun, Weiyuan Sun, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiology, Stanford University, University of Pennsylvania, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, Stanford University,

Abstract Preview: Purpose:
The small animal radio-neuromodulation platform developed in our previous work utilized focused kV x-ray beams rotating and translating in predefined trajectories to irradiate small, mm si...

Beam Orientation Optimization in IMRT Using Sparse Mixed Integer Programming and Non-Convex IMRT Fluence Map Optimization

Authors: Yabo Fu, Yang Lei, Yu Lei, Haibo Lin, Ruirui Liu, Tian Liu, Kenneth Rosenzweig, Charles B. Simone, Shouyi Wei, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York Proton Center

Abstract Preview: Purpose: Beam orientation optimization (BOO) in intensity-modulated radiation therapy (IMRT) is traditionally a complex, non-convex problem tackled with heuristic methods. This study benchmarks global...

Deep Learning-Based Dose Distribution Prediction for Automation of Treatment Planning

Authors: Yaspal Badyal, Rabten Datsang, Tianjun Ma, William Song

Affiliation: MVision AI, Virginia Commonwealth University

Abstract Preview: Purpose: Deep learning (DL)-based dose distribution predictions for prostate cancer show significant potential for OAR sparing compared to manually optimized treatment plans. We aim to generate clinic...

Development of a Knowledge-Based Planning Model for Intensity Modulated Proton Therapy in Breast Cancer Treatment

Authors: Parker Anderson, Elizabeth L. Bossart, Jonathan Cyriac, Nesrin Dogan, Robert Kaderka, Yihang Xu

Affiliation: University of Miami, University of Miami, Sylvester Comprehensive Cancer Center, University of Miami Sylvester Comprehensive Cancer Center

Abstract Preview: Purpose:
Knowledge-based planning (KBP) can enhance the treatment planning process in cancer radiotherapy (RT). By training a KBP model with high-quality treatment plans developed by experts, dose-...

Development of an Inverse Treatment Planning System for Precision Small Animal Radiotherapy

Authors: Zihao Liu, Qiwei Wu, Yanfei Xiong, Yidong Yang, Ning Zhao

Affiliation: Department of Engineering and Applied Physics, School of Physical Sciences, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China

Abstract Preview: Purpose: To develop an inverse planning framework that optimizes beam angles and intensities for small animal radiotherapy and to validate its accuracy and effectiveness.
Methods: The inverse plann...

Multi-Variat, Multi-Model, and Multi-Patient: From Pure Feasibility to Generalizability in Machine Learning Outcome Prediction Model-Based Treatment Plan Optimization

Authors: Martin Frank, Oliver Jรคkel, Niklas Wahl

Affiliation: Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Karlsruhe Institute of Technology (KIT)

Abstract Preview: Purpose: Machine learning (ML) models on normal tissue complication and tumor control probability ((N)TCP) exploiting e.g. dosiomic and radiomic features are playing an increasingly important role in ...

Universal Range Modulators for Flash Proton Therapy: 3D Printing of Stackable Variable Density Units

Authors: Eric S. Diffenderfer, Lei Dong, Alejandro Garcia, Wenbo Gu, Michele M. Kim, Alexander Lin, Kai Mei, Peter B. Noรซl, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou

Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania

Abstract Preview: Purpose: We present a novel 3D-printed range-modulating devices with spatially modulated density for FLASH particle therapy. By varying density distributions, spread-out Bragg peaks(SOBPs) can be gene...