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Results for "low risk": 75 found

A Clinically Aligned Embedding Model for Glioma Prognostication Via Radiology-Pathology Report Matching

Authors: Steve Braunstein, Yannet Interian, Hui Lin, Bo Liu, Janine Lupo, Olivier Morin, Benedict Neo

Affiliation: Radiation Oncology, University of California San Francisco, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, University of California San Francisco, Department of Data Science, University of San Francisco, University of San Francisco

Abstract Preview: Purpose: Large Language Models (LLMs) demonstrate strong general text comprehension but remain limited in oncology due to insufficient contextual alignment. We pilot embedding alignment through radiol...

A Comparison of Non-Adaptive Versus Online Adaptive Radiotherapy for Prostate Cancer Using FLOW-RT-- Fast, AI-Driven but Learning-Enabled, Online Adaptive Workflow for Radiotherapy

Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Beatriz Guevara, Lauren E Henke, Angela Jia, Rojano Kashani, Kyle O'Carroll, Alex T. Price, Adithya Reddy, Atefeh Rezaei, Daniel E Spratt, Runyon C. Woods

Affiliation: University Hospitals Seidman Cancer Center

Abstract Preview: Purpose: To evaluate the effect of unedited AI-generated contours used for online adaptive radiotherapy (FLOW-ART) on the plan quality of prostate treatments as compared to non-adaptive (non-ART) proc...

A Novel Design of Photon-Counting Static Cone-Beam CT System for Dedicated Breast Imaging

Authors: Ahad Ollah Ezzati, Yile Fang, Xiaoyu Hu, Xun Jia, Kai Yang, Yuncheng Zhong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University

Abstract Preview: Purpose: With breast cancer being one of the most prevalent cancers, regular screening is an effective strategy to mitigate the risk of malignancy. However, conventional energy-integrating detector (E...

AI-Based Registration-Free 3T T2-Weighted MRI Synthesis Using Truefisp MRI Acquired on a 0.35T MR-Linac System

Authors: Hilary P Bagshaw, Mark K Buyyounouski, Cynthia Fu-Yu Chuang, Yu Gao, Dimitre Hristov, Lianli Liu, Lawrie Skinner, Lei Xing

Affiliation: Department of Radiation Oncology, Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose:
MR-guided radiation therapy has introduced a significant leap in cancer treatment by allowing adaptive treatment. The low-field MR-guided system predominantly uses the TrueFISP sequence, w...

AI-Driven Drug Discovery through an Interactive Analysis of Radiomics and Biological Insights in Glioblastoma

Authors: Nobuki Imano, Yuzuha Kadooka, Daisuke Kawahara, Misato Kishi, Yuji Murakami, Shumpei Onishi

Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Neurosurgery, Hiroshima University Hospital

Abstract Preview: Purpose: Radiomics has proven useful in predicting overall survival in glioblastoma (GBM) patients, but consistent molecular correlations remain unidentified, leaving its biological basis unclear. Thi...

Achieving Consistent Calcium Score in Lung Cancer Screening: Influence of Cardiac Phases

Authors: Emi Ai Eastman, Chao Guo, Christina Lee, Xinhua Li, Alexander W. Scott, Yifang (Jimmy) Zhou

Affiliation: Cedars-Sinai Medical Center

Abstract Preview: Purpose:
Smoking is one of the risk factors for coronary artery disease. It is desirable to estimate the coronary artery calcification (CAC), a key biomarker for atherosclerosis and cardiovascular ...

An FMEA-Based Approach to Improve the Process and Quality Control on MR Imaging from Outside Diagnostic Imaging Centers to be Used for Radiation Treatment Planning

Authors: Olivier Blasi, Eric Cameron, Brad K. Lofton

Affiliation: CAMP, Colorado Assn in Medical Phys (CAMP)

Abstract Preview: Purpose:
Magnetic Resonance (MR) imaging obtained from external centers for radiation therapy (RT) planning can suffer from suboptimal protocols and geometric distortions. These issues can require ...

Anatomical Noise Power Exponent (β) As an Image-Based Risk Factor for Breast Cancer

Authors: Yile Fang, Leslie Lamb, Nathaniel David Mercaldo, Kai Yang

Affiliation: Massachusetts General Hospital

Abstract Preview: Purpose: To quantitatively evaluate power-law exponent β as a potential image-based breast cancer risk factor.

Methods: Two groups of breast cancer screening cohorts (target vs. control, 20 sub...

Assessing the Impact of Weighting Dose Volume Histograms By Variable Relative Biological Effectiveness for Radiation-Induced Lymphopenia Risk Prediction

Authors: Yan Chu, Madison Emily Grayson, Radhe Mohan, Pablo P. Yepes

Affiliation: UT Health Science Center at Houston, Rice University, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Radiation-induced lymphopenia (RIL) is a common adverse effect of radiation therapy, negatively impacting overall survival and anti-PD1 immunotherapy efficacy. Our lab previously developed a ...

Assessment of Daily Target Volume and Dose Variations in Adaptive MR-Guided Radiotherapy for Pancreatic Cancer Patient

Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Haley Park, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny

Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose:
Pancreatic cancer poses therapeutic challenges due to the proximity of critical organs, requiring precise radiotherapy. Magnetic resonance (MR)-guided linear accelerators provide daily ima...

Assessment of Deep Learning Models for 3D Dose Prediction in Prostate Cancer SIB-IMRT Using MR-Linac

Authors: Hao-Wen Cheng, Jonathan G. Li, Chihray Liu, Wen-Chih Tseng, Guanghua Yan

Affiliation: University of Florida

Abstract Preview: Purpose: This study develops and evaluates deep learning (DL) models for predicting 3D dose distributions in simultaneous integrated boost (SIB) prostate cancer treatment using the Elekta Unity MR-Lin...

Automated Quantification of Irradiation-Induced Effects on Ribosome Biogenesis Using Foundational AI Model and Image Analysis

Authors: Kyle J. Wang, Yading Yuan

Affiliation: Bergen County Technical High School, Columbia University Irving Medical Center, Department of Radiation Oncology

Abstract Preview: Purpose: Genotoxic cancer therapies inevitably damage normal cells, particularly circulating hematopoietic cells, posting a risk for therapy-induced leukemia. This study aims to develop an automated i...

BEST IN PHYSICS IMAGING: Dosimetric Impact of Iodinated Contrast Agent on Fibroglandular Tissue in Contrast-Enhanced Digital Mammography

Authors: Hannah Grover, Andrew J. Sampson

Affiliation: Oregon Health & Science University, UT Health San Antonio

Abstract Preview: Purpose: The goal of this work was to quantify the dosimetric impact of iodinated contrast on fibroglandular breast tissue to better inform clinical risk and benefit assessments when determining the m...

Clinical Feasibility of a Deep-Learning-Based Auto Contouring through Qualitative and Dosimetric Assessments

Authors: Sara Endo, Takeshi Fujisawa, Hidehiro Hojo, Masaki Nakamura, Hidenobu Tachibana

Affiliation: Department of Radiation Oncology, National Cancer Center Hospital East, Radiation Safety and Quality Assurance Division, National Cancer Center Hospital East

Abstract Preview: Purpose: To assess the clinical feasibility of deep learning (DL)-based automated contouring through qualitative and quantitative assessments.

Methods: Sixty cases were chosen, including 3 OARs...

Cloud Workflow AI Apps for Radiotherapy Image Analysis Using Pycerr and Seven Bridges-Cancer Genomics Cloud

Authors: Aditya P. Apte, Joseph O. Deasy, Sharif F. Elguindi, Aditi Iyer, Jue Jiang, Eve Marie LoCastro, Jung Hun Oh, Amita Shukla-Dave, Harini Veeraraghavan

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: We present publicly shareable applications (apps) for AI-based radiotherapy segmentation workflows with pyCERR on Seven Bridges Cancer Genomics Cloud-based platform (CGC-SB)
Methods: Runni...

Comparison of AI-Based and Ants for Longitudinal Deformable Image Registration in Head and Neck Cancer

Authors: Aditya P. Apte, Joseph O. Deasy, Jue Jiang, Nancy Lee, Sudharsan Madhavan, Nishant Nadkarni, Lopamudra Nayak, Harini Veeraraghavan, Wei Zhao

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: To track early response to radiotherapy using digital twins, it is crucial to quantify tumor volume and mass changes. Traditional tumor detection methods, particularly in image registration, ...

Comparison of Linear Energy Transfer Volume Histograms from Two Beam Geometries in a Pediatric Chordoma Patient Treated with Intensity Modulated Proton Therapy

Authors: Michael Confer, Mark A. Newpower

Affiliation: University of Oklahoma Health Sciences Center

Abstract Preview: Purpose: A pediatric patient recently presented to our clinic for treatment for chordoma, which was near the brainstem. The clinician elected to treat this patient using intensity modulated proton the...

Contrast-Free Full Intracranial Vessel Geometry Estimation from MRI with Metric Learning-Based Inference

Authors: Zhaoyang Fan, Eric Nguyen, Dan Ruan, Jiayu Xiao

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiology, University of Southern California, University of Southern California

Abstract Preview: Purpose: MR vessel wall imaging (VWI) has been shown to be effective for evaluating intracranial atherosclerosis disease. However, VWI typically also requires an MR angiography (MRA) in the same imagi...

Deep Learning Aided Oropharyngeal Cancer Autoplanning

Authors: Mark Bowers, Gabriel Carrizo, Jimmy Caudell, Vladimir Feygelman, Kevin Greco, Christian Hahn, Jihye Koo, Kujtim Latifi, Fredrik Lofman, Jacopo Parvizi, Muqeem Qayyum, Caleb Sawyer

Affiliation: RaySearch Laboratories, Moffitt Cancer Center

Abstract Preview: Purpose: Head and neck (H&N) radiotherapy planning is complex, with multiple competing objectives. We endeavored to improve efficiency of planning by developing a deep learning (DL) model trained to p...

Development of a Comprehensive Thoracic Re-Irradiation Database and Investigation of Time-Dependent Dose-Recovery Dynamics for Toxicity Modeling

Authors: Victoria Doss, Tsion Gebre, Rachel B. Ger, Esi A Hagan, Elaina Hales, Russell K Hales, Xun Jia, Heng Li, Dezhi Liu, Todd R. McNutt, Meti Negassa, Anas Obaideen, Tinker Trent, K. Ranh Voong, Cecilia FPM de Sousa

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: As cancer care advances, more patients require re-irradiation, yet evidence-based data is lacking. This study aimed to develop a thoracic re-irradiation database and explore time-dependent re...

Dosimetric Analysis of Lymphopenia after Lung Irradiation and Modeling the Probability of Normal Tissue Complications

Authors: Tianyuan Dai, Xiaoying Fan, Shuting Wang, Yong Yin

Affiliation: Department of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences

Abstract Preview: Purpose: Decreased lymphocytes increase the risk of infections and other problems. Radiation exposure can cause the development of severe lymphopenia. In this study, we used a dynamic blood flow model...

Efficient Denoising of Low-Statistic Influence Matrices Using a Diffusion Transformer-Based Framework for Adaptive Proton Therapy

Authors: Yuzhen Ding, Hongying Feng, Jason Michael Holmes, Baoxin Li, Wei Liu, Daniel Ma, Lisa McGee, Samir H. Patel, Jean Claude M. Rwigema, Sujay A. Vora

Affiliation: Arizona State University, Department of Radiation Oncology, Mayo Clinic, Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose:
Intensity-modulated proton therapy (IMPT) is a preferred treatment modality for head and neck (H&N) cancer patients, offering precise tumor targeting while sparing surrounding organs at ri...

Enhanced Pelvic Organ Segmentation Using LLM-Driven Prompts for Prostate Cancer Low-Dose-Rate Brachytherapy

Authors: Yang Lei, Tian Liu, Ren-Dih Sheu, Meysam Tavakoli, Jing Wang, Kaida Yang, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Emory University

Abstract Preview: Purpose:
The study aimed to improve target and organ at risk (OAR) segmentation in low-dose-rate brachytherapy (LDR-BT) for prostate cancer treatment, by integrating clinical guidelines into deep l...

Enhancing Proton Treatment and Mitigating Radiation-Induced Lung Injury Using a Novel Cycle Diffusion Approach for Lung Ventilation Estimation

Authors: Yang Lei, Haibo Lin, Tian Liu, Charles B. Simone, Shouyi Wei, Ajay Zheng

Affiliation: Icahn School of Medicine at Mount Sinai, New York Proton Center

Abstract Preview: Purpose: Radiation-induced lung injury (RILI), encompassing pneumonitis and fibrosis, represents a critical dose-limiting factor in lung cancer radiation therapy. Variability in treatment outcomes is ...

Enhancing Radiation Oncology Imaging with a Novel Variational Model Decomposition, Radon Transformation, and Kohonen Self-Organizing Map Denoising Framework

Authors: Hassan Bagher-Ebadian, Justine M. Cunningham, Anthony J. Doemer, Mohammad M. Ghassemi, Joshua P. Kim, Benjamin Movsas, Kundan S Thind

Affiliation: Michigan State University, Henry Ford Health

Abstract Preview: Purpose: Reduction of noise in medical images critically enables improved accuracy in delineating tumors and organs at risk, leading to more precise treatment planning and safer image-guided radiation...

Evaluating Three Practical Approaches to Managing Dose Accumulation in Normal Tissues during Radiation Re-Treatments

Authors: Derek A. Fiedler, Nixon Gutierrez, Quyen L. Jones, Zejian Liu, Tatsiana Reynolds

Affiliation: Texas Oncology, Minnesota Oncology, US Oncology

Abstract Preview: Purpose: Optimize patient safety and treatment efficacy during radiation re-treatment planning. Provide a comprehensive comparison of the methods by focusing on their applicability, accuracy, and limi...

Evaluating the Impact of Spot Spacing on Dosimetric Outcomes in Dynamic Arc Proton Therapy for Prostate SBRT

Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Umesh Rana, Hina Saeed, Nishan Shrestha, Somol Sunny

Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: DynamicARC is a novel pencil beam scanning (PBS) proton therapy technique with the potential to provide more conformal dose distributions and reduce treatment time. This study investigates th...

Evaluation of Concomitant Imaging Dose in 4D-CBCT Guided Thoracic Radiotherapy

Authors: Yuchao Hu, Yajun Jia, Zhangmin Li, Yong Sang, Jianan Wu, Man Zhao

Affiliation: Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, Guangzhou Concord Cancer Hospital, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

Abstract Preview: Purpose: To evaluate the imaging dose of 4D-CBCT in patients treated with thoracic radiotherapy.
Methods: A model of the Elekta XVI imaging system was created in TOPAS software. Percentage depth do...

Exploring NSCLC Microenvironments: Multi-Score Survival Models Integrationg Radiomics-Based Regional Imaging Features and Genomics

Authors: Nobuki Imano, Daisuke Kawahara, Misato Kishi, Yuji Murakami

Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University

Abstract Preview: Purpose: This study aims to develop a comprehensive Multi-score by integrating Radiomics-score (Rad-score), Gene-score derived from gene expression levels, and tumor environment Rad-score (TE-Rad-scor...

Feasibility of Developing a Radiomic Fingerprint to Predict Pulmonary Embolism Clot Types to Aid in Determining Intervention for Intermediate-Risk Patients.

Authors: Lindsay Hammons, Lisa Baumann Kreuziger, Haidy G. Nasief, Matthew Scheidt, Farrell Sean, Antonio Sosa Lozano

Affiliation: Division of Hematology and Oncology, University of Washington, Vascular and Interventional Radiology, Medical college of wisconsin, Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Venous thromboembolism, which includes pulmonary embolism (PE), is the third leading cause of acute cardiovascular syndrome behind myocardial infarction and stroke. Current research categoriz...

First Demonstration of Prostate Radiotherapy Plan Optimization on an IBM Quantum Computer

Authors: Keisuke Fujii, Masahiro Kitagawa, Arezoo Modiri, Yuichiro Nakano, Ken N. Okada, Robabeh Rahimi, Akira SaiToh, Amit Sawant, Satoyuki Tsukano, Baoshe Zhang

Affiliation: University of Maryland, University of Maryland in Baltimore, Department of Computer and Information Sciences, Sojo University, Center for Quantum Information and Quantum Biology, Osaka University, Maryland University Baltimore, Department of Radiation Oncology, University of Maryland School of Medicine

Abstract Preview: Purpose: Fully personalized radiotherapy requires computational resources far exceeding those of conventional CPU/GPU systems. This study explores the use of quantum computing (QC) in radiotherapy pla...

Free-Breathing VMAT and IMRT Versus Deep Inspiration Breath- Hold 3D-CRT Techniques for Left-Breast Cancer: A Practical Solution for Developing Countries

Authors: Md. Yousuf Ali, Parvin Akhter Banu, Ehteshamul Hoque, Qazi Mushtaq Hussain, Md Jobairul Islam, Md. Abdul Mannan, Sadia Afrin Sarah, Mostafa Aziz Sumon, Ahammad Al Mamun Sweet, AFM Kamal Uddin

Affiliation: Labaid Cancer Hospital & Superspeciality Centre

Abstract Preview: Purpose: Radiotherapy for left-sided breast cancer can induce cardiac injury. Deep Inspiration Breath Hold (DIBH) is a technique that minimizes cardiac exposure during treatment. This study compares d...

From Supine to Upright: A Geometric Shift in Perspective

Authors: Ben Durkee, Renata Farrell, Carri K. Glide-Hurst, Colin Harari, Alex Singleton Kuo, Chase Ruff, Jordan M. Slagowski, Yuhao Yan

Affiliation: University of Wisconsin, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Advances in upright CT and patient positioning system now enables high quality daily CT imaging and treatment delivery in the upright position, providing benefits including reduced internal m...

Hypersight-Archer Study: Improved Target Coverage and Organ-at-Risk Sparing Via Adaptive Radiotherapy of Head and Neck Cancer Using Direct-Dose Calculation on Cone Beam CT

Authors: Cheryl Anderson, Lara Best, Amanda Cherpak, Jennifer DeGiobbi, Marc C. LeBlanc, R. Lee MacDonald, Peter R. Martin, Natasha McMaster, Murali Rajaraman, James L. Robar, Lucy Ward, Derek Wilke, Kenny Zhan

Affiliation: Department of Radiation Oncology, QE2 Cancer Centre, Nova Scotia Health

Abstract Preview: Purpose: This work investigates the potential benefit of adaptive planning using the Ethos radiotherapy system (Varian Medical Systems) with direct-dose calculation on HyperSight cone beam CT (CBCT) f...

Impact of Tumor-to-Normal Ratio and Glass Microsphere Particle Density on Local Progression-Free Survival Following Lobar Yttrium-90 Radioembolization

Authors: Jason Chiang, Magnus Dahlbom, Veronica Hankil, Xinyi Li, Catherine (Caffi) Meyer, Kyung Hyun Sung

Affiliation: UCLA, University of California, Los Angeles

Abstract Preview: Purpose:
Yttrium-90 (90Y) radioembolization is a well-established therapy for large or multifocal liver tumors. Accurate dosimetry is critical but remains challenging, as low particle density risks...

Implementing a Fully Automated, Web-Based Dashboard for Tracking Patient Progression through the Radiotherapy Workflow

Authors: James M. Lamb, Jack Neylon, Dylan P. O'Connell

Affiliation: Department of Radiation Oncology, University of California, Los Angeles

Abstract Preview: Purpose: Communication is imperative to safe, accurate, and timely radiotherapy. The past decade has seen a significant shift toward higher doses and shorter fractionations, which has in turn led to i...

Improving Head and Neck Radiotherapy Accuracy through Real-Time Volumetric Imaging Using a Kalman Filter Approach

Authors: Youssef Ben Bouchta, Chen Cheng, Owen Thomas Dillon, Mark Gardner, Paul J. Keall, Purnima Sundaresan

Affiliation: Radiation Oncology Network, Western Sydney Local Health District, Image X Institute, Faculty of Medicine and Health, The University of Sydney

Abstract Preview: Purpose: There are three clinical motivations for real time IGRT in head and neck cancer radiation therapy: (1)50% of patients experience anxiety from the patient mask (2)patient motion still occurs d...

In Vivo Dosimetry for Cied Management – Is It Really Needed?

Authors: Anthony J. Doemer, Aharon Feldman, Stephen J. Gardner, Brett M. Miller, Benjamin Movsas, Farzan Siddiqui, Chadd Smith, Kundan S Thind, Kyle Verdecchia

Affiliation: Henry Ford Health

Abstract Preview: Purpose: To evaluate the efficacy of calculation-only approach for CIED risk-level assessment.
Methods: A total of 86 patients were included in this retrospective analysis. For each patient, in viv...

Influence of the α/ß Ratio on Dose Constraints in Radiotherapy of Prostate Cancer

Authors: Marwa Y. Abdel Tawwab, Amin E Amin, Abdullah M. ElSharif, Somaia Metwally Elsayed, Magdy M. Khalil

Affiliation: School of Applied Health Science, Badr University in Cairo (BUC), Cairo, Egypt, Medical Physics, Radiation Oncology Department, Faculty of Medicine, Ain Shams University, Medical Biophysics, Department of Physics, Faculty of Science, Helwan University

Abstract Preview: Purpose: Prostate cancer radiotherapy typically employs conventional fractionation schedules over approximately eight weeks. This study investigates the effect of variations in the α/β ratio on dose c...

Integration of Dosimetric Scorecard Analysis into Knowledge-Based Planning Improves Model Performance for VMAT Post-Mastectomy Radiation Therapy

Authors: Ryan Clark, Jon Cornelisse, Kenny Guida, Anthony Magliari, Lesley Rosa, Megan Smith, Shane R Stecklein

Affiliation: Office of Medical Affairs, Varian, A Siemens Healthineers Company, Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: Post-mastectomy radiation therapy (PMRT) can pose a challenge for planners of all levels of experience. For cases where 3D conformal therapy yields undesirable results (i.e., dose heterogenei...

Inter-Fractional Target Similarity during Tandem and Ring HDR Brachytherapy

Authors: Olubunmi Odunola Aregbe, Clara Ferreira, Margaret Reynolds, David A. Sterling

Affiliation: University of Minnesota, University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis

Abstract Preview: Purpose: Current best practices recommend daily imaging and planning for Tandem and Ring (T&R) HDR patient plans. Accurate target delineation is a critical, yet time consuming step in this process. Th...

Intraoperative Dynamic Contrast-Enhanced Fluorescence Imaging in Quantifying Tissue Perfusion of Amputation Patients

Authors: Logan M. Bateman, Xu Cao, Jonathan T. Elliott, Lillian A. Fisher, Ida Leah Gitajn, Xinyue Han, Eric R. Henderson, Shudong Jiang, Jessica M. Sin, Yue Tang

Affiliation: Dartmouth College, Dartmouth-Hitchcock Medical Center

Abstract Preview: Purpose: Adequate tissue perfusion is essential for fracture healing and infection prevention, as it supplies oxygen, nutrients and antibiotics to the injury area. However, current methods of assessin...

Investigation and Machine-Learning Modeling of Dosimetric Discrepancies in Eclipse-Calculated Head and Neck Treatment Plans

Authors: Andres Portocarrero Bonifaz, Ian Schreiber

Affiliation: CARTI Cancer Center

Abstract Preview: Purpose: To explore how calculation grid resolution, along with other planning factors, affects head and neck dose calculation accuracy and contributes to potential discrepancies in the Eclipse Treatm...

Knowledge-Based Planning for Chest Wall with Lymph Nodes Irradiation VMAT

Authors: Nesrin Dogan, Panagiota Galanakou, Robert Kaderka

Affiliation: University of Miami, Sylvester Comprehensive Cancer Center, University of Miami Sylvester Comprehensive Cancer Center

Abstract Preview: Purpose:
To develop knowledge-based treatment planning (KBP) for volumetric modulated arc therapy (VMAT) in chest wall treatments with regional nodal involvement. Given the challenges posed due to ...

Leveraging Hybrid Quantum Solvers for Eye Plaque Brachytherapy Treatment Planning Optimization

Authors: Xianjin Dai, PhD, Wu Liu, Eric Nguyen, Lei Xing, Lewei Zhao

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose: Recent developments in hybrid quantum solvers, which combine quantum and classical processing, enable greater flexibility to tackle problems outside the limited scope of pure quantum computin...

Measurement of Microscopic Velocity Gradients Using Magnetic Nanoparticles in Blood Flow

Authors: Scott Gordon-Wylie, Scott Gordon-Wylie, Dhrubo Jyoti, John B. Weaver, Terrence Welch

Affiliation: Flow Aluminum, Dartmouth College, Dartmouth-Health

Abstract Preview: Purpose: Identifying vulnerable plaques is critical to preventing stroke and myocardial infarction. There are two components contributing to the risk of rupture: the mechanical integrity of the plaque...

Mesh-Based Multiregion Model of Adult Human Kidneys for Dosimetric Evaluation of Radiopharmaceutical Therapy

Authors: John P. Aris, Wesley E. Bolch, Chansoo Choi, Carlos G. Colon-Ortiz, Robert Joseph Dawson, Abdul-Vehab Dozic, Amy M. Geyer, Harald Paganetti, Shreya P. Pathak, Julia D. Withrow

Affiliation: St. Luke's Health System, Massachusetts General Hospital, University of Florida

Abstract Preview: Purpose: The goal of this study was to enhance the accuracy of renal dosimetry in radiopharmaceutical therapy (RPT) by developing a more detailed and precise kidney model. In RPT, accurate dose estima...

Multi-Modality Artificial Intelligence for Involved-Site Radiation Therapy: Clinical Target Volume Delineation in High-Risk Pediatric Hodgkin Lymphoma

Authors: Tyler J Bradshaw, Sharon M Castellino, Steve Y Cho, David Hodgson, Bradford S Hoppe, Kara M Kelly, Andrea Lo, Sarah Milgrom, Xin Tie

Affiliation: Department of Radiation Oncology, University of Toronto, Department of Radiology, University of Wisconsin, University of Colorado Anschutz, Department of Medical Physics, University of Wisconsin, Department of Radiation Oncology, Mayo Clinic, Department of Radiation Oncology, BC Cancer, Vancouver Center, Department of Radiology, University of Wisconsin - Madison, Roswell Park Comprehensive Cancer Center, Emory University School of Medicine

Abstract Preview: Purpose: Clinical target volume (CTV) delineation for involved-site radiation therapy (ISRT) in Hodgkin lymphoma (HL) is time-consuming due to the need to analyze multi-time-point PET/CT scans co-regi...

Multi-Vendor Validation of a Deep Learning-Based Synthetic CT Generation Model for MR-Only Radiotherapy Planning in the Pelvis

Authors: Gregory Bolard, Rabten Datsang, Sarah Ghandour, Timo Kiljunen, Pauliina Paavilainen, Sami Suilamo, Katlin Tiigi

Affiliation: Turku University Hospital, Virginia Commonwealth University, MVision AI, North Estonia Medical Centre, Docrates Cancer Center, Hopital Riviera-Chablais

Abstract Preview: Purpose: To verify the performance of a vendor-neutral deep learning model for synthetic CT generation from T2-weighted and balanced steady-state MR sequences to support both MR-only simulation and MR...

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Authors: Houssam Abou Mourad, Christopher Ackerman, Stephen Adler, Kirk Aduddell, Muhammad K. Afghan, Hamid G. Aghdam, Diego Aguilar, Kang-Hyun Ahn, Francis Ai, Hua Ai, Ray Anthony Aikens, Manik Aima, Victoria Ainsworth, Erfan Akbari, Blessing Akinro, Rani Al-Senan, Khalid Alabbasi, Sam Alam, Daniel Alexander, Mohammed H. Aljallad, Mazin T. Alkhafaji, Ahmad K. Alkhatib, Scott J. Alleman, James Logan Allen, Ibtisam Almajnooni, Tiba Alnaqshabandi, Murat Alp, Stephen J. Amadon, Riska Amilia, Ala Amini, Shiho Amster, Mason R. Anders, Erin Angel, Ledi Anggara, John A. Antolak, Debora Antonio, Felicity Appiah, Haiqa Arain, Lahcen Arhjoul, Ali V. Aritkan, Muhammad Arshad, Mark E. Artz, Nathan S. Artz, Frank A Ascoli, John R. Ashburn, Benjamin Astarita, Masakazu Atsumi, Rex G. Ayers, Tara M. Bachman, Nina L. Bahar, Bing Bai, Michael J. Bailey, Chris Baird, Mohammad Bakhtiari, Andrew J. Ballesio, Isabel Balvoa, Qinan Bao, Jeffrey J. Barbarits, Joseph Barbiere, Philip C. Bardos, Gary T. Barnes, John C. Barrett, Divya Bartley, Steven J. Bartolac, Robert Barton, Christopher P. Bass, Loni Bates, Alan Baydush, John E. Bayouth, Stephen Beach, Kevin Beaudette, Kaelyn Becker, Natalie A. Beckmann, Colleen Beer, Sepideh Behinaein, Jake M. Bell, David M. Bellezza, Maria R. Bellon, Ahmed Benelfassi, Stephanie Louise Bennett, Todd Bernath, Kate Bevins, Nicholas B. Bevins, Brian J. Bismack, David Blaich, Anthony P. Blatnica, Joseph W. Blickenstaff, Steven Blum, Maggie Bobbett, Dayna Bodensteiner, Daniel Boedeker, Robert C. Boggs, Jason D. Bond, Sjirk N. Boon, Jennifer M. Borsavage, Ryan J. Bosca-Harasim, Ryan J. Bosca-Harasim, Satya R. Bose, Todd Bossenberger, Cristina Boswell, Djamal Boukerroui, Christopher M. Bowen, Aaron Brammer, Rich Brancaleoone, Eric Brass, Luis Bravo, William Breeden, Christina Breeze, Eric E. Brost, Justin L. Brown, Karen L. Brown, Marissa Brown, Norman Lee Brown, Payton Brown, Patrick V. Brunick, Ryan Brunkhorst, Gwendolyn P. Brunner, Camelia E. Bunaciu, Maria Bunta, Olwen Burton, Karim Butalag, Priscilla F. Butler, Angela Cagwin, Jeffrey L. Campbell, Warren G. Campbell, Tyler Cantrell, Xu Cao, Yanan Cao, Peter F. Caracappa, Amanda M. Caringi, Joe Caron, Joshua Carter, Kenneth W. Cashon, Sarah Castillo, Everett Cavanaugh, Suran Chae, Abhi Chakrabarti, PhD, Philip Chan, Jina Chang, Sha X. Chang, Youssef M. Charara, Pierre E. Charpentier, Priyanka Chaudhary, Senthamil Selvan Chelliah, Chen Chen, Doris Chen, Kuan Ling Chen, Max Chen, Mingyue Chen, Mu Chen, Xinan Chen, Yie Chen, Yong Chen, Caroline Cheney, Shyh-Shi R. Chern, Stephen Thomas Chesser, Kin Man Cheung, Pai-Chun Melinda Chi, Yuwei Chi, Omar Chibani, Hung Ching, Gwi Ae Cho, Jongmin Cho, David Choi, Wing Yan Choi, Nitish Chopra, Daniel Christ, Olav I. Christianson, Emmanuel Christodoulou, Heeteak Chung, Sophia Claudio, Arely Clavel, William J. Clouse, Gilad Cohen, Michael S. Cohen, Vladimir Collantes, Jason Collier, Jacob Collins, Daria C. 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Affiliation: DTC Consultants, NL Health, Dartmouth Hitchcock Medical Center, ProCure Proton Therapy Center, Medical & Radiation Physics, Inc, Augusta University, Genesis Healthcare Partners, Michigan Medicine, Washington DC VA Medical Center, VA Medical Center, Mercy Southeast Hospital, Food And Drug Administration, University of Iowa, Advanced Radiation Physics Service, Inc, University of Pittsburgh, University of Wisconsin, Wellspan Health, Good Samaritan Hospital, Howard University Hospital, St. Mary's Memorial Health Center, Penn State Milton S. 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Radiation Oncology, Renown Health, Purdue Univ, Beth Israel Deaconess Medical Center, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Holy Family Hospital, OhioHealth, IBA Dosimetry, Memorial Hospital Gulfport, University of Florida, George Washington Univ, University of Cincinnati Medical Center, Hubbard, Zickgraf, & Broadbent, Accuray Inc, UVRMC, MIM Software, Massachusetts General Hospital and Harvard Medical School, Mem. Sloan Kettering Cancer Ctr, UF Health Proton Therapy Institute, California Medical Physics, Inc., Henry Ford Health, UPMC Hillman Cancer Center, Vanderbilt University School of Medicine, Saddleback Memorial Medical Center, Stony Brook University Medical Center, University of Pennslyvania, TOP Physics Consulting, Nuvance/Norwalk Hospital, Oregon Health & Science Univ, Brigham & Women's Hospital, University of Pennsylvania, McLaren – Greater Lansing, American Board of Radiology, Penn Medicine | Virtua Radiation Oncology, University of Tennessee, OneOncology, University of Colorado, Indiana University Medical Center, Stronach Regional Cancer Centre, Yale New Haven Health, Vanderbilt University Medical Center, Emory Healthcare / Winship Cancer Institute, Cape Fear Valley Radiation Oncology, Northwell Health, Sutter Health, Virginia Mason Medical Center, MUSC Health- Florence Medical Center, Departement of Radiation Oncology, Curie Institute, Paris, University of Michigan, MD Anderson Cancer Center, University of Alabama at Birmingham, Radiology Inc., Cedars Sinai Hospital, Roswell Park Cancer Institute, Duke University Health System, VA Hospital, DVA Medical Ctr., JFK Medical Center, Mount Sinai West, National Cancer Institute, Chung Nam National University Sejong Hospital, Indiana Univesity, AdventHealth Daytona Beach, Orlando Health, Clinical Research Institute HUS, Northwest Medical Physics Center, University of Pennsylvania, Penn Medicine, Kettering Health Network, Children's Mercy Kansas City, IBA, UMass Memorial Hospital, US Oncology, Kaiser Permanente Southern California Medical Group, The Queen's Health System, NewYork-Presbyterian, Miami Valley Hospital, Karlsruhe Institute of Technology, Piedmont Hospital, Accuray Inc., VARIAN - Advanced Oncology Solutions, GE Healthcare, Virtua Health, Northwestern Medicine Chicago Proton Center, CARO/Montgomery Cancer Center, Walter Reed National Military Medical Center, InterMountain Health Care, Englewood Hospital and Medical Center, Henry Ford Health System, Fluke Health Solutions, Texas Oncology, PA, Inova Alexandria Hospital, New Milford Hospital, Fox Chase Cancer Center, Radiation Therapy and Cancer Inst, Penn State College of Medicine, University of California San Francisco, Unity of Oncologic Therapy S.A., Canon Medical Systems USA, Kaiser Permanente, Baptist Health Paducah, Salina Regional Health, Centre d'Oncologie de la Cote Basque, Minneapolis Radiation Oncology, Coastal Carolina Radiation Oncology, Saint Francis Hospital, Advocate Christ Medical Ctr, Universidad de Costa Rica, CAMP, Blessing Hospital, Texas Oncology Cancer Ctr, CommonSpirit Health, Navy Medical Forces Atlantic, Regions Hospital, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Methodist Hospital, Champlain Valley Physicians Hospital, Mayo Clinic Jacksonville, OHSU, Promedica Health System, Arthur JE Child Comprehensive Cancer Centre, Rhode Island Hospital / Warren Alpert Medical, UPMC Pinnacle Health, Vassar Brothers Hospital, McLeod Regional Medical Center, RJ Tokarz MIRS, St. Francis Hospital, Astarita Associates, Inc., UC Davis Medical Center, Mount Nittany Medical Center, Covenant Radiation Center, National Institute of Standards and Technology, AdventHealth Orlando, St Helena Hospital, Icon Cancer Centre, University of Washington, Indiana University, TrueNorth Medical Physics LLC, Medstar Georgetown University Hospital, Harold Alfond Center for Cancer Care, MN Oncology, Jupiter Medical Center, GE HealthCare, Rochester General Hospital, Piedmont Health, Atrium Health, Minneapolis VA Health Care System, CentraCare Health System, OMPC Diagnostic LLC, Evergreen Health Medical Center, CAMC Cancer Center - Beckley, University of Kansas Medical Center, Avera McKennan, Cleveland Clinic, Louisiana Tech University

Abstract Preview: N/A...

Non-Contact Blood Pressure Estimation Using Remote Photoplethysmography Signals Extracted from Facial Video: A Deep Learning Approach

Authors: Mavlonbek Khomidov, Jong-Ha Lee

Affiliation: Department of Biomedical Engineering, Keimyung University, Department of Computer Engineering, Keimyung University

Abstract Preview: Purpose: In this research, we aim to estimate blood pressure using remote photoplethysmography (rPPG) signal extracted from facial video. This method provides non-invasive and contactless, continuous ...

Optimizing Fractionation Schedules for De-Escalation Radiotherapy in Head and Neck Cancers Using Deep Reinforcement Learning

Authors: Zhongjie Lu

Affiliation: Department of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine

Abstract Preview: Purpose: Patients with locally-advanced head and neck squamous cell carcinomas(HNSCCs), particularly those related to human papillomavirus(HPV), often achieve good locoregional control(LRC), yet they ...

Patient Dosimetry in Medical Imaging and Radiotherapy: A New Course for Medical Physics Students

Authors: Wesley E. Bolch, Robert Joseph Dawson, Wyatt Smither

Affiliation: University of Florida

Abstract Preview: Purpose: To design a novel course that reinforces key medical physics concepts through a series of practicum sessions, where students learn and apply the Monte Carlo radiation transport code, PHITS, c...

Personalized and Automated Head & Neck Radiotherapy Planning with AI-Guided Optimization

Authors: Michael Bowers, Patrik Brodin, Madhur Garg, Rafi Kabarriti, William P. Martin, Todd R. McNutt, Julie Shade, Wolfgang A. Tomé, Christian Velten

Affiliation: Johns Hopkins University, Oncospace, Inc., Montefiore Medical Center

Abstract Preview: Purpose: Development of an automated planning tool utilizing AI generated patient-specific dose-volume histogram predictions for rapid H&N plan generation.
Methods: Planning best-practices were dev...

Physician-Centered Decision-Making Tool for Individualized Outcome-Based Treatment Planning

Authors: Soren Bentzen, Arezoo Modiri, Zaker Rana, Amit Sawant, Lena Specht, Ivan Vogelius

Affiliation: University of Maryland, University of Maryland in Baltimore, Dept. Of Oncology Copenhagen University Hospital – Rigshospitalet, Maryland University Baltimore, Department of Radiation Oncology, University of Maryland School of Medicine

Abstract Preview: Purpose: There is wide inter-physician radiotherapy planning variability for lymphomas and no systematic way to individualize a plan with respect to patient-specific outcome risks. In response to this...

Preplanning Physics Consultation with Voxelized EQD2: A Proactive Approach for Streamlined Dose Management in High-Risk Re-Irradiation Patients

Authors: Katja M. Langen, Mark McDonald, Bill Stokes, Yinan Wang, Suk Whan (Paul) Yoon

Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Effective dose management in high-risk re-irradiation (ReRT) patients entails early, detailed special physics consultation (SPC) to mitigate risks from cumulative radiation dose. SPCs have tr...

Proposed Method for Optimization of Lattice Radiation Therapy Using an Advanced Ring Gantry Linac

Authors: Eduardo Florian, Osmar Obdulio Hernandez, Otto Hurtarte, Milton Ixquiac, Erick Orlando Montenegro, Franky Eduardo Reyes, Edgar Aparicio Ruiz, Kevin Vega, Vicky de Falla

Affiliation: Liga Nacional Contra el Cancer, Liga Nacional Contra el Cancer/INCAN, Liga Nacional Contra el Cancer / INCAN, Liga Nacional Contra el Cancer and Universidad de San Carlos de Guatemala, Liga Nacional Contra el Cáncer / INCAN

Abstract Preview: Introduccion:
Lattice Radiation Therapy (LRT) is a form of spatially fractionated radiation therapy (SFRT) designed to improve control of large tumors by delivering ablative doses while minimizing ...

Prospective Hazard Analysis in Radiation Therapy – a Systematic Review

Authors: Jeremy T. Booth, Sonja Dieterich, Jonathan Hindmarsh, Paul J. Keall

Affiliation: Northern Sydney Cancer Centre, Royal North Shore Hospital, UC Davis Medical Center, Image X Institute, Faculty of Medicine and Health, The University of Sydney

Abstract Preview: Purpose: Prospective hazard analysis (PHA) is a core medical physics function. PHA was investigated by AAPM Task Group 100 for the purpose of keeping patients safe and assessing the risks of novel tec...

Python Scripts for Film-Based PDD and Profile Analyses of HDR Surface Applicators

Authors: Jack Neylon

Affiliation: Department of Radiation Oncology, University of California, Los Angeles

Abstract Preview: Purpose: Commissioning surface applicators is notoriously laborious. In addition, when commissioning Varian surface applicators with vertically positioned source, we found limited data and resources a...

Quantifying the Impact of Tissue Inhomogeneities on Calculated Dosimetry within LDR Brachytherapy

Authors: Fatemeh Akbari, Deidre Batchelar, Luc Beaulieu, Nathan E. Becker, Juanita Crook, Dakota Mckeown, Matthew Jonathan Muscat, Rowan M. Thomson

Affiliation: Département de physique, de génie physique et d'optique, Université Laval, BC Cancer Agency, UBC, Carleton University, BC Cancer - Kelowna, BC Cancer

Abstract Preview: Purpose:
To study the effects of inter-seed attenuation and tissue inhomogeneities on dose-volume metrics of critical structures in prostate low-dose-rate (LDR) permanent seed implant brachytherapy...

Quantitative Analysis of Long-Term Optical Density Variations of Irradiated and Un-Irradiated EBT3 Films

Authors: Rick Holly, Sumudu Katugampola

Affiliation: Gesinger Medical Center, Geisinger Medical Center

Abstract Preview: Purpose:
To quantitatively analyze long term variations in optical density of un-irradiated and irradiated EBT3 radio-chromic films and their effects on dose calibration curves in a clinical settin...

Radiobiological Modeling of Tumor Control and Normal Tissue Response Following Mlc-Based Sfrt to Extensive Breast and Chest Wall Tumors

Authors: Ramesh Boggula, Yash Somnay, Hualin Zhang

Affiliation: Radiation Oncology, Keck School of Medicine of USC, Wayne State University

Abstract Preview: Purpose: Spatially fractionated radiation therapy (SFRT) allows delivery of therapeutic doses to bulky tumors otherwise limited by dose-volume effects that threaten organ-at-risk tolerances. For negle...

Radiopathomic Characterization of Chemoradiation Resistance in Preclinical Models of Head and Neck Cancer

Authors: Rico Castillo, Katherine Gonzalez, Casey C. Heirman, Kyle J. Lafata, Xiang Li, Yvonne M Mowery, Yvonne M Mowery, Allison Pittman, Ashlyn G. Rickard, Breylon Riley

Affiliation: Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh

Abstract Preview: Purpose: To evaluate the relationships between quantitative imaging biomarkers and chemoradiation resistance in head and neck squamous cell carcinoma (HNSCC) using preclinical mouse models.

Met...

Realistic Modeling of Vasculature Flow and Oxygen Distribution in Normal Tissue and Glioblastoma

Authors: Yi Fan, Andrew Friberg, Costas Koumenis, Kevin Teo, Ioannis I Verginadis, Ledi Wang, Jennifer Wei Zou

Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania

Abstract Preview: Purpose: Glioblastomas (GBM) are aggressive and lethal malignancies characterized by their highly refractory nature, contributing to a five-year survival rate of approximately 7%. Physically, GBM exhi...

Retrospective Postimplant Dosimetry: Comparison of Line and Point Source for 131cs Low Dose Rate Intracranial Implant Brachytherapy

Authors: Tirthraj Adhikari, Timothy J Allen, Abdullah A. Alshreef, Clara Ferreira

Affiliation: Medical School Department of Radiation Oncology University of Minnesota, University of Minnesota, Loma Linda University Medical Center

Abstract Preview: Purpose: GammaTile Brachytherapy with 131Cs is an effective treatment for glioblastomas, offering local control with minimal radiation necrosis. While the line source model is preferred for dose distr...

Revealing Unseen Risks: Hands-on Technologist Education to Prevent MRI Incidents Using Ferromagnetic Detecting Wands

Authors: Chris Beasley, Ngara Linda Bird, Flora Ivanova, Erin B. Macdonald, Lauren M. Neldner, Beth Reed, Scott H. Robertson

Affiliation: School of Medicine, Duke University, Duke University, Duke University Health System

Abstract Preview: Purpose: To develop a hands-on, data-driven educational program to improve MRI technologists' understanding and effective use of ferromagnetic detecting (FMD) wands.
Methods: A 30-minute interactiv...

Technical Feasibility and Accuracy of Dynamic Longitudinal Couch Motion during Beam Delivery

Authors: Chonthicha Bunchuailuea, David Geeler, Martin Sabel, Claas Wessels

Affiliation: Varian Medical Systems

Abstract Preview: Purpose: Elongated treatment sites, such as craniospinal treatments, pose multiple challenges in today’s practices, requiring multiple CBCTs for position verifications per fraction, which might increa...

The Dosimetric Impact of the Incremental Discontinuation of Bolus during Postmastectomy Chest Wall Radiation Treatment for Breast Cancer.

Authors: Anthony R Bardwell, Dong Won Kim, Faith S Kim, Isaac Y Kim, Juying Zhang

Affiliation: Kaiser Permanente

Abstract Preview: Purpose: When a patient develops a significant skin reaction at some point during postmastectomy radiotherapy, a clinical decision is often made to discontinue the planned daily use of bolus. The aim ...

The Feasibility of Ethos-Based Pulsed Reduced Dose-Rate (PRDR) Radiotherapy

Authors: Chia-Lung Chien, Renteng Hou, Wen C. Hsi, Faraz Kalantari, Ganesh Narayanasamy, Zhong Su

Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)

Abstract Preview: Purpose:
PRDR is an effective re-irradiation treatment for patients who have already reached the tolerance dose to their organs at risk (OARs). While PRDR is implemented on TrueBeam by limiting the...

The Gatekeeping of Medical Physics Leading to the Underrepresentation of Black and Hispanic Women in the Field

Authors: Emily Hansen, Tyler Kaulfers, Alois M. Ndlovu, Niara Rowe, Roland Teboh

Affiliation: Montefiore Einstein University Hospital, Hackensack University Medical Center

Abstract Preview: Purpose: A topic often discussed is the disparity of women in medical physics, overlooking the absence of Black and Hispanic women in the field. The intersectionality within marginalized communities i...

Tracking Deposited Nanoparticle Cluster Sizes in Inhalation Based Nanoparticle-Enhanced Radiotherapy

Authors: Victoria Susan Ainsworth, Wilfred F. Ngwa, Erno Sajo

Affiliation: University of Massachusetts Lowell, Johns Hopkins University

Abstract Preview: Purpose: In nanoparticle-enhanced radiotherapy, the dose enhancement is function of the particle size. At therapeutic concentrations, the number density of nanoparticles gives rise to a high rate of i...

Two-Stage Clustering and Auto Machine Learning to Predict Chemoradiation Response in Tumor Subregions on FDG PET for La-NSCLC

Authors: Stephen R. Bowen, Shijun Chen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Qianqian Tong, Jiajie Wang, Shouyi Wang, Faisal Yaseen

Affiliation: The University of Texas at Austin, Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Fred Hutchinson Cancer Center, University of Texas at Arlington

Abstract Preview: Purpose: Tumor subregion clustering and prediction of region-specific response can augment assessments and adaptive treatment decisions. A modeling framework was constructed to predict chemoradiation ...

Ultrafast Proton Delivery with Pin Ridge Filters (pRFs): A Novel Approach for Motion Management in Proton Therapy

Authors: Zachary Diamond, Pretesh Patel, Sibo Tian, Yinan Wang, Xiaofeng Yang, David Yu, Ahmal Jawad Zafar, Jun Zhou

Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Active breath-hold techniques effectively mitigate respiratory motion but poses challenges for patients who are unable to tolerate the procedure. Conventional planning relies on multiple ener...

Universal Anatomical Mapping and Patient-Specific Prior Implicit Neural Representation for MRI Super-Resolution

Authors: Jie Deng, Yunxiang Li, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Magnetic Resonance Imaging (MRI) has exceptional soft tissue contrast and an essential role in radiotherapy. The introduction of clinical MR-LINACs has enabled adaptive radiotherapy (ART) usi...

Why do you need so many physicists to treat 600 fractions per year? How to advocate for needed brachytherapy physics resources

Authors: Alexandra Rink

Affiliation: Department of Medical Biophysics, University of Toronto

Abstract Preview: N/A...