Authors: Grant Evans, Maxwell Arthur Kassel, Charles Shang, Stephen Shang
Affiliation: South Florida Proton Therapy Institute, SFPRF
Abstract Preview: Purpose: Proton pencil beam scanning therapy is particularly sensitive to field translational shifts and beam range variations, which can degradation of dose distribution and compromise the treatment....
Authors: Maria F. Chan, Seng Boh Gary Lim, Shih-Chi Lin, Dustin W. Lynch, Usman Mahmood, Jeonghoon Park
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To explore the feasibility of using GafChromic LD-V1 film for annual imaging dose assessment across kV radiography, fluoroscopy, and cone beam computed tomography (CBCT) imaging protocols, as...
Authors: Victor B. Kassey, Maciej M. Kmiec, Periannan Kuppusamy, Sergey V. Petryakov, Conner Ubert
Affiliation: Dartmouth College
Abstract Preview: Purpose: Tumor hypoxia—a state of reduced oxygen supply—is well known to affect treatment response, particularly in radiotherapy and chemotherapy. Oxygen-enhanced magnetic resonance imaging (OE-MRI) u...
Authors: Yuanhan Chen, Ziqiang Chen, Qi Cheng, Feng Ding, Rui Fang, Shengwen Guo, Li Hao, Qiang He, Haiquan Huang, Yu Kuang, Xinling Liang, Yuanjiang Liao, Guohui Liu, Chen Lu, Qingquan Luo, Jing Sun, Yanhua Wu, Zhen Xie, Qin Zhang, Lang Zhou
Affiliation: South China University of Technology, Dongguan people's hospital, Sichuan Provincial People's Hospital, People’s Hospital of Xinjiang Uygur Autonomous Region, Second Hospital of Anhui Medical University, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangdong Easy Life Information Technology Co., Ltd, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Medical Physics Program, University of Nevada, Second Hospital of Jilin University, Chongqing Ninth People's Hospital
Abstract Preview: Purpose: Acute kidney injury (AKI) is a global healthcare issue with a rapid onset and severe consequences. Repeated measurement of serum creatinine (SCr) levels, a clinical standard of care, is cruci...
Authors: Rachael Blair, Les Butler, Lillian Dickson, Kyungmin Ham, Charles Hartman, Kenneth (Kip) Matthews, Corinne Vanya
Affiliation: Louisiana State University, University of Minnesota, Refined Imaging LLC, Center for Advanced Microstructures and Devices
Abstract Preview: Purpose:
To develop and evaluate an x-ray interferometry system (XIS) for low-dose, high-sensitivity diagnostic imaging of lung diseases such as chronic obstructive pulmonary disease (COPD), asthma...
Authors: Mark E Artz, Jiyeon Park, Lori Rice, Mohammad Saki, Sanjeev Shukla, Michael Vieceli
Affiliation: University of Florida Health Proton Therapy Institute, Department of Radiation Oncology, University of Florida College of Medicine, UF Health Proton Therapy Institute, Department of Urology, University of Florida College of Medicine
Abstract Preview: Purpose: To investigate how varying levels of DNA repair mutations affect the LET sensitivity of prostate cancer cells.
Methods: The prostate cancer cell lines Du145 (low DNA repair mutations), PC3...
Authors: Gueorgui Gueorguiev, Katia Sergieva, Filip Simeonov, Tsvetelina Todorova, Bozhidar Vladimirov
Affiliation: National Centre of Radiobiology and Radiation Protection, Queen Giovanna University Hospital
Abstract Preview: Purpose: Dosimetry audit is an essential tool enhancing confidence in the accuracy of treatment delivery and in prevention of radiation treatment incidents. Current work depicts how novel nationwide r...
Authors: Jacqueline M. Andreozzi, Tess Armstrong, Shiva Bhandari, John M Bryant, Jessica M Frakes, David J. Gladstone, Sarah E Hoffe, Kujtim Latifi, Arash Naghavi, Steven Nichols, Ibrahim M. Oraiqat, Russell Palm, Gage H. Redler, Stephen A Rosenberg, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Thayer School of Engineering, Dartmouth College, Department of Radiation Oncology, Ohio State University, Moffitt Cancer Center, Department of Radiation Oncology, Moffitt Cancer Center
Abstract Preview: Purpose: The MR-linac provides unique opportunities for integrating advanced imaging into radiotherapy workflows, but the lower sensitivity of systems like the 0.35T model can pose challenges for diff...
Authors: Huiming Dong, Jonathan Pham, X. Sharon Qi, Ann Raldow
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: The study aimed to investigate longitudinal apparent diffusion coefficient (ADC) as an early biomarker of treatment response in patients with locally advanced rectal cancer (LARC) undergoing ...
Authors: Wei Wei, Yading Yuan
Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology
Abstract Preview: Purpose: To investigate an uncertainty modeling method to improve the performance of cancer classification with the ability to produce uncertainty score.
Methods: Deep learning has achieved state-o...
Authors: Li Tong, Chuyan Wang, Zhengkui Wang, Yingli Yang, Jie Zhang
Affiliation: Shanghai United imaging Healthcare Advanced Technology Research Institute, Shanghai United Imaging Healthcare Co., LTD, Department of Radiology, Ruijin Hospital, Institute for Medical Imaging Technology, Ruijin Hospital
Abstract Preview: Purpose:
Pelvic radiotherapy (RT)-induced bone marrow (BM) damage affects patient prognosis by causing hematologic toxicity. However, consensus on BM-sparing (BMS) RT is still lacking, owing to the...
Authors: Jeffrey D. Bradley, Steven J. Feigenberg, Cole Friedes, Yin Gao, Xun Jia, Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, Johns Hopkins University
Abstract Preview: Purpose: Understanding how physicians evaluate plans is critical for automatic planning and ensuring consistent, high-quality care. While deep-learning models excel in complex decision-making, the lac...
Authors: James M. Lamb, Dishane Chand Luximon, Jack Neylon, Rachel Petragallo, Moritz Ritter, Timothy Ritter
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, ETH Zurich, VCU Health System, Department of Radiation Oncology, University of Colorado
Abstract Preview: Purpose: Anomalies in cone beam computed tomography (CBCT) radiotherapy image guidance can signal treatment deviations. Repetitive review of setup image registrations by humans is inefficient, prone t...
Authors: William E Burrell, Philip F. Durham, Anne N Hubbard, Yohan Akeakamai Walter, Hsinshun Terry Wu
Affiliation: Willis Knighton Cancer Center
Abstract Preview: Purpose: Linear accelerator (LINAC)-based single-isocenter, multi-target (SIMT) treatment has streamlined the stereotactic radiosurgery (SRS) workflow. However, off-isocenter treatment carries multipl...
Authors: Maria Jose Almada, Oscar Apaza, Carlos Bohorquez, Ezequiel Cabrera, Rogelio Diaz Moreno, Maximiliano Musso, Rosa Petit, Carlos Daniel Venencia, Lucy D. Wolfsberger
Affiliation: LAP, FaMAF, UNC, Instituto Zunino - Fundacion Marie Curie
Abstract Preview: Purpose:
PSQA employs gamma analysis to verify the planned versus delivered dose. Evaluating the effectiveness of PSQA techniques in identifying errors is crucial. This study aims to incorporate ML...
Authors: Xiangli Cui, Wei Han, Jie Li, Lingling Liu
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Hefei Cancer Hospital, Chinese Academy of Sciences, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences
Abstract Preview: Purpose: To investigate the influence of tissue heterogeneity on proton beam linear energy transfer (LET) and relative biological effectiveness (RBE) using nine RBE models. This study quantifies the i...
Authors: Omar Awad, Alfredo Enrique Echeverria, Issam M. El Naqa, Daniel Allan Hamstra, Yiding Han, Ryan Lafratta, Abdallah Sherif Radwan Mohamed, Piyush Pathak, Zaid Ali Siddiqui, Baozhou Sun, Vincent Ugarte
Affiliation: H. Lee Moffitt Cancer Center, Harris Health, Baylor College of Medicine
Abstract Preview: Purpose:
Accurate detection and segmentation of brain metastases are critical for diagnosis, treatment planning, and follow-up imaging but are challenging due to labor-intensive manual assessments ...
Authors: Anthony J. Doemer, Aharon Feldman, Stephen J. Gardner, Brett M. Miller, Benjamin Movsas, Farzan Siddiqui, Chadd Smith, Kundan S Thind, Kyle Verdecchia
Affiliation: Henry Ford Health
Abstract Preview: Purpose: To evaluate the efficacy of calculation-only approach for CIED risk-level assessment.
Methods: A total of 86 patients were included in this retrospective analysis. For each patient, in viv...
Authors: Mohammadreza Ay, Nahal Daneshgar, Nima Kasraie, Abbas Monsef, Zeinab Peymani, Hadi Rezaei, Peyman Sheikhzadeh
Affiliation: University of Minnesota Medical School, Radiation Oncology, Department of Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Shiraz University of Medical Sciences, Department of Medical Physics, Tehran University of Medical Sciences, Department of Medical Physics and Biomedical Engineering, UT Southwestern Medical Center, Imam Khomeini Hospital Complex,Tehran University of Medical Sciences
Abstract Preview: Purpose:
This study aims to design and simulate an innovative pediatric-dedicated SPECT scanner optimized for children’s unique anatomical and safety needs by enhancing sensitivity in data acquisit...
Authors: Yuqi Yang, Fang-Fang Yin
Affiliation: Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Reactive oxygen species (ROS) are unstable molecules which play important roles in the cellular process after Flash radiotherapy. The rapid changes in ROS levels during treatment may provide ...
Authors: Sina Mossahebi, Pouya Sabouri, Kayla Schneider, James W Snider
Affiliation: University of Maryland School of Medicine, Proton International, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Conventional patient-specific QA (PSQA) for intensity-modulated proton therapy (IMPT) requires extensive measurements, straining resources in single-room proton centers. This study evaluat...
Authors: Smith Apisarnthanarax, Clemens Grassberger, John Kang, Yejin Kim, Justin Leu, Dominic A. Maes, Matthew J. Nyflot, Ramesh Rengan, Annemarie Shepherd, Jing Zeng
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Washington, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington and Fred Hutchinson Cancer Center
Abstract Preview: Purpose: Reirradiation (ReRT) is a rapidly growing clinical challenge driven by better systemic therapy and longer survival, though clear guidelines for ReRT are lacking. Fitting traditional normal ti...
Authors: Qihui Lyu, Dan Ruan, Ke Sheng, Jingjie Yu
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: The robotic arm radiotherapy platform enables flexible delivery of non-coplanar and non-isocentric radiotherapy with variable Source-to-Isocenter Distances (SIDs). However, the high degrees o...
Authors: Kaitlyn M Betz, David Dunkerley, Eric Johnson, Kalina V Jordanova, Kathryn E. Keenan, Samuel D Oberdick, Gregory P. Penoncello, Stephen E Russek
Affiliation: Dept of Radiology, Stanford, University of Colorado School of Medicine, NIST, College of Wooster
Abstract Preview: Purpose: Examine use of low-field MRI and multiparametric analysis for 3D MRI-readable biomimetic gel dosimetry. Low-field MRIs are compact, inexpensive, and portable. They could be located within rad...
Authors: Magdalena Bazalova-Carter, Ross I. Berbeco, James Day, Xinchen Deng, Chelsea Amanda Saffron Dunning, Dianne M. Ferguson, Matthew W. Jacobson, Toby Morris, Marios Myronakis, Jericho Daniel O'Connell, Fides Schwartz, Jainil Shah, Aaron Sodickson
Affiliation: Brigham and Womens Hospital, University of Massachsetts Lowell and Dana-Farber Cancer Institute Boston, Medical Physics Department, Medical School, University of Thessaly, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, University of Washington, University of Victoria, Siemens Healthineers, Dana Farber/Brigham and Women's Cancer Center, Brigham and Women's Hospital
Abstract Preview: Purpose: While CT imaging has advanced with improved machine design, we propose further gains can be achieved by enhancing sensitivity to contrast agents. Current CT sensitivity is limited to 1% bismu...
Authors: Daniel O Connor, Mary Feng, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger, Jess E. Scholey, Ke Sheng, DI Xu, Wensha Yang, Yang Yang
Affiliation: UCSF, University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, University of San Francisco, Department of Radiology, University of California, San Francisco, University of California San Francisco, Siemens Medical Solutions USA Inc.
Abstract Preview: Purpose: The scanning time for a fully sampled MRI is lengthy. Compressed sensing (CS) has been developed to minimize image artifacts in accelerated scans, but the required iterative reconstruction is...
Authors: Samuel L. Brady, Shruti Hegde, Alexander Knapp, Usman Mahmood, Joseph G. Meier, Elanchezhian Somasundaram, Zachary Taylor
Affiliation: Cincinnati Children's Hospital Medical Ctr, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Cincinnati Children's Hospital Medical Center, Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose:
To assess how two benchmark multi-organ CT segmentation models respond to varying image noise levels.
Methods:
This study utilized the pediatric CT dataset from The Cancer Imaging Ar...
Authors: Mavlonbek Khomidov, Jong-Ha Lee
Affiliation: Department of Biomedical Engineering, Keimyung University, Department of Computer Engineering, Keimyung University
Abstract Preview: Purpose: In this research, we aim to estimate blood pressure using remote photoplethysmography (rPPG) signal extracted from facial video. This method provides non-invasive and contactless, continuous ...
Authors: Jeremy S. Bredfeldt, Daniel W. Cail, Maria A. Czerminska, Cindy I. Hancox, David Hu, Benjamin Karasko, Claire Keun Sun Park
Affiliation: Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, Brigham and Women's Hospital, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: To develop a robust clinical protocol for in vivo dosimetry in radiotherapy using the myOSLchip Optically Stimulated Luminescent Dosimeter (OSLD) system by performing characterization and eva...
Authors: Yussuf A. Abdelal, Junguo Bian, Michael Delafuente, Sebastien A. Gros, Hyejoo Kang, Luke Layman, M Mahesh, John C. Roeske
Affiliation: Department of Radiology and Medical Imaging, Stritch School of Medicine, Loyola University Medical Center, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Johns Hopkins Univ
Abstract Preview: Purpose: This study evaluates the feasibility of optimizing 4DCBCT imaging protocols for gated lung SBRT, by reducing dose while maintaining the image quality required for accurate patient alignment.<...
Authors: Go Akamatsu, Han Gyu Kang, Chie Seki, Hitomi Sudo, Hideaki Tashima, Chie Toramatsu, Hidekatsu Wakizaka, Iwao Yamaya, Taiga Yamaya
Affiliation: National Institutes for Quantum Science and Technology
Abstract Preview: Purpose:
Tumor oxygen status, which provides important information to optimize particle therapy, may constantly change during a treatment period of several weeks. However, it is impractical to perf...
Authors: David P. Adam, Xun Jia, Youfang Lai, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Radiopharmaceutical therapy is experiencing a resurgence in interest due to its potential of treating widespread metastatic disease in a patient-specific manner. Accurately measuring and desc...
Authors: Marian Axente, Mandeep Kaur
Affiliation: Emory University
Abstract Preview: Purpose: To validate a low-cost optical imaging system for respiratory monitoring by comparing its accuracy and feasibility against the clinical gold standard in human subjects.
Methods: Following ...
Authors: Chris Beasley, Ngara Linda Bird, Flora Ivanova, Erin B. Macdonald, Lauren M. Neldner, Beth Reed, Scott H. Robertson
Affiliation: School of Medicine, Duke University, Duke University, Duke University Health System
Abstract Preview: Purpose: To develop a hands-on, data-driven educational program to improve MRI technologists' understanding and effective use of ferromagnetic detecting (FMD) wands.
Methods: A 30-minute interactiv...
Authors: Hilary Louisa Byrne, Paul J. Keall, John Kipritidis, Jeremy Lim
Affiliation: Northern Sydney Cancer Centre, University of Sydney, Image X Institute, Faculty of Medicine and Health, The University of Sydney
Abstract Preview: Purpose:
Non-contrast CT ventilation imaging (CTVI) has been developed as a cost-effective and accessible alternative to PET/SPECT V/Q imaging for visualizing lung function. However, the sensitivit...
Authors: Rajeev K. Badkul, Ronald C Chen, Ying Hou, Harold Li, Chaoqiong Ma, Jufri Setianegara
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose:
Postimplant urinary toxicity is common in prostate low-dose-rate (LDR) brachytherapy. We developed a machine learning (ML) model to explore the correlation between spatial dose distributio...
Authors: Guillermo Daniel Alvarez, Daniel Fino, Rocio Luz Gilli, Dorian Alexander Romero
Affiliation: School Foundation of Nuclear Medicine, INTECNUS Foundation, Nuclear Medicine and Radiotherapy Center of Southern Patagonia
Abstract Preview: Purpose: To evaluate the anatomical, functional, and molecular information from PET/MR images with F18-PSMA to identify intraprostatic lesions and delineate a boost in stereotactic body radiotherapy (...
Authors: Petr Bruza, Yao Chen, David J. Gladstone, Lesley A Jarvis, Brian W Pogue, Kimberley S Samkoe, Yucheng Tang, Shiru Wang, Rongxiao Zhang
Affiliation: NVIDIA Corp, Dartmouth College, Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, University of Missouri, University of Wisconsin - Madison
Abstract Preview: Purpose: Cherenkov imaging provides real-time visualization of megavoltage radiation beam delivery during radiotherapy. Patient-specific bio-morphological features, such as vasculature, captured in th...
Authors: Muhammad Ramish Ashraf, Kerriann Casey, Suparna Dutt, Jie Fu, Edward Elliot Graves, Xuejun Gu, Hao Jiang, Brianna Caroline Lau, Billy W Loo, Weiguo Lu, Rakesh Manjappa, Stavros Melemenidis, Erinn Bruno Rankin, Lawrie Skinner, Luis Armando Soto, Murat Surucu, Vignesh Viswanathan, Zi Yang, Amy Shu-Jung Yu
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine, Department of Comparative Medicine, Stanford University School of Medicine, Department of Radiation Oncology, Stanford University Cancer Center
Abstract Preview: Purpose: The intestine is a classical preclinical model for studying radiation injury, and histological quantification of intestinal crypts is a key assay for assessing this response. However, substan...