Authors: Sorour Hosseini, YuHuei Jessica Huang, Thomas Boyd Martin, Geoffrey S. Nelson, Nicholas Pierre Nelson, Hui Zhao
Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah
Abstract Preview: Purpose: To evaluate image quality—including noise, contrast-to-noise ratio (CNR), uniformity, and low-contrast visibility (LCV)—on the HyperSight and TrueBeam cone-beam computed tomography (CBCT) pla...
Authors: Dale W. Litzenberg, Ikechi S Ozoemelam, Rowan Paplanus, Michael Pillainayagam, Donald A. Roberts
Affiliation: University of Michigan, Oregon Health & Science University
Abstract Preview: Purpose: Clinical linear accelerators use dual foil scattering systems designed to achieve large uniform fields (up to 25×25cm²), which can reduce beam fluence by up to 93% compared to the unmodified ...
Authors: Parminder S. Basran, Wyatt Flanders, Skylar Sylvester
Affiliation: Cornell University
Abstract Preview: Purpose: To develop a reliable, efficient, and low-cost methodology for quantifying radiation doses using radiochromic film and a custom-built lightbox and to evaluate the system's performance compare...
Authors: Michalis Aristophanous, Steven Blum, Laura I. Cervino, Antonio L. Damato, Karen Episcopia, Chi Huang, Shih-Chi Lin, Michelle K. Savacool
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Varian Ethos (Varian Medical Systems, Palo Alto, CA) is a 6 MV flattening-filter-free (FFF) only machine, posing a challenge in creating homogeneous dose distributions when using manual 3D-CR...
Authors: J Isabelle Choi, Meng Wei Ho, Isabel Lin, Hang Qi, Qi Zeng, Ajay Zheng
Affiliation: New York Proton Center, Scarsdale High School
Abstract Preview: Purpose: Proton therapy is a promising treatment modality for breast cancer due to its unique dosimetric advantage. Accurate dose calculation is critical to ensure effective treatment outcomes. The fo...
Authors: Petr Bruza, Megan Clark, David J. Gladstone, Lesley A Jarvis, Allison Matous, Roman Vasyltsiv, Rongxiao Zhang
Affiliation: Dartmouth Health, Dartmouth College, Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, University of Missouri
Abstract Preview: Purpose: On-patient dosimeters assist in clinical decision-making by measuring surface dose, but single-point measurements cannot monitor area-wide distributions and are misleading in high-gradient re...
Authors: Darwin Abraham Garcia, Michael P. Grams, Scott C Lester, Maryam Mashayekhi, Douglas John Moseley, Robert W Mutter, Sean S Park, Chrystian Quintero Mateus
Affiliation: Mayo Clinic - Rochester, Mayo Clinic
Abstract Preview: Purpose: MBRT delivers sub-millimeter wide regions of high “peak” (~10s Gy) and low “valley” (~1 Gy) doses to treat cancer. MBRT commissioning is performed in flat, uniform plastic water. Thus, differ...
Authors: Ramesh Boggula, Jay W. Burmeister
Affiliation: Wayne State University, Karmanos Cancer Center, Gershenson ROC, Wayne State University School of Medicine
Abstract Preview: Purpose: This study evaluated the performance of a hybrid Compton camera for real-time imaging during the administration of Lu-177-based radiopharmaceuticals, including Pluvicto and Lutathera. The aim...
Authors: Takahiro Kato, Teiji Nishio, Masataka Oita, Robabeh Rahimi, Yuki Tominaga, Yushi Wakisaka
Affiliation: University of Maryland, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University, Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Medical Physics Laboratory, Division of Health Science, Osaka University Graduate School of Medicine, Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
Abstract Preview: Purpose: This study evaluated dose verifications and lateral penumbra improvements for scanned proton therapy plans with and without a multi-leaf collimator (MLC) under various air gaps.
Methods: E...
Authors: ChangSeon Kim, Andrew Lukban, Mario Serrano-Sosa, Ching-Ling Teng, Nadia M. Vassell
Affiliation: Northwell, Mount Sinai Beth Israel
Abstract Preview: Purpose:
The flexible nature of ballistic gelatin and 3D printed material such as PLA lend themselves to phantom studies in brachytherapy. While these materials can allow for easy simulation of cat...
Authors: Giavanna Luisa Jadick, Patrick J La Riviere
Affiliation: University of Chicago
Abstract Preview: Purpose: We assess two multi-measurement acquisition schemes for material decomposition with x-ray phase-contrast imaging (XPCI); demonstrating for the first time that multi-distance imaging can match...
Authors: Mohammad Nazmul Alim, Regina DeWitt
Affiliation: Department of Physics, East Carolina University,, Department of Physics, East Carolina University
Abstract Preview: Purpose: This study quantifies the ability of Luxel (Al₂O₃:C) to measure radiation dose from a Moxtek X-ray source. Key aspects of OSL dosimetry, including OSL curves, dose response, depth dose, and b...
Authors: Joseph Barbiere, Joseph Hanley, Brett Lewis, Jay Mistry, Alois M. Ndlovu, Roland Teboh
Affiliation: Hackensack University Medical Center, HUMC, Jersey Shore University Medical Center
Abstract Preview: Purpose:
Quantitative PET-CT can evaluate clinical response to radiotherapy. For tumors less than approximately 3cm partial volume effects due to the poor PET resolution makes accurate measurement ...
Authors: Guang-Pei Chen, Renae Conlin, Juan A. Garcia-Alvarez, Kirk Morris, Haidy G. Nasief, Eenas A. Omari, Eric S. Paulson
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Cumulative dose limits make replacing and calibrating Metal Oxide Semiconductor Field Effect dosimeters (MOSFET-d) used for in-vivo dosimetry a common clinical task. Calibration protocols for...
Authors: Ted Lynch
Affiliation: Sun Nuclear, a Mirion Medical Company
Abstract Preview: Purpose: A novel ultrasound quality assurance method is presented that constructs “synthetic spheres” at arbitrary locations within the image frame by combining correlation length measurements from a ...
Authors: Kazi Towmim Afrin, Imad M. Ali, Jordan West
Affiliation: University of Oklahoma Health Sciences Center, University of Oklahoma
Abstract Preview: Purpose: To simulate total-body-irradiation (TBI) with field-in-field treatment planning techniques and test portal dosimetry for dose verification and quality assurance.
Methods: CT images of full...
Authors: Eric S. Diffenderfer, Lei Dong, Alejandro Garcia, Wenbo Gu, Michele M. Kim, Alexander Lin, Kai Mei, Peter B. Noël, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: We present a novel 3D-printed range-modulating devices with spatially modulated density for FLASH particle therapy. By varying density distributions, spread-out Bragg peaks(SOBPs) can be gene...
Authors: Farhad Jafari, Brandon Hai Nguyen
Affiliation: Department of Radiation Oncology, University of Minnesota Medical School, Department of Radiology, University of Minnesota
Abstract Preview: Purpose: To validate a bottom-up approach to dosimetry in nuclear medicine.
Methods: A pharmacokinetic model is developed to represent the flow of activity between different compartments of the...