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Results for "mediated pdt": 4 found

Comparison of Multispectral Singlet Oxygen Luminescent Dosimetry (MSOLD) and Singlet Oxygen Explicit Dosimetry (SOED) in BPD-Mediated PDT for Mice

Authors: Robert H Hadfield, Madelyn Johnson, Baozhu Lu, Hongjing Sun, Vikas Vikas, Brian C. Wilson, Weibing Yang, Timothy C. Zhu

Affiliation: University of Glasgow, University of Toronto, University of Pennsylvania

Abstract Preview: Purpose:
Multispectral Singlet Oxygen Luminescent Dosimetry (MSOLD) has been developed as a real-time in vivo dosimetry technique for Photodynamic Therapy (PDT). This study investigates the feasibi...

Direct in-Vivo Real-Time Singlet Oxygen Detection in Photofrin-Mediated Photodynamic Therapy (PDT) Using Multispectral Singlet Oxygen Dosimetry (MSOLD)

Authors: Theresa Busch, Robert H Hadfield, Madelyn Johnson, Baozhu Lu, Hongjing Sun, Brian C. Wilson, Weibing Yang, Timothy C. Zhu

Affiliation: University of Glasgow, University of Toronto, University of Pennsylvania

Abstract Preview: Purpose: Direct detection of singlet-state oxygen (ยนOโ‚‚) is crucial for advancing type II photodynamic therapy (PDT), but its short lifetime makes in vivo measurement highly challenging. Although Photo...

Investigating in-Vivo Megavoltage Radiodynamic Therapy from 6 to 45MV Photon Beam Radiation Therapy with 5-Aminolevulinic Acid

Authors: Lili Chen, Dusica Cvetkovic, Chang Ming Charlie Ma, Dae-Myoung Yang

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose: 5-aminolevulinic acid (5-ALA)-mediated radiodynamic therapy (RDT) has been shown to be an effective treatment option using high-energy photon beams. RDT utilizes tumoricidal capabilities caus...

Tumor Response to Catalytic Effect of Carbamide Peroxide to Megavoltage Radiodynamic Therapy with 5-Aminolevulinic Acid

Authors: Lili Chen, Dusica Cvetkovic, Chang Ming Charlie Ma, Dae-Myoung Yang

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose: Cytotoxicity caused by the reactive oxygen species (ROS) is a mechanism for treating cancer cells in radiation therapy. 5-aminolevulinic acid (5-ALA)-mediated radiodynamic therapy (RDT), whic...