Authors: Jingyuan Chen, Sheng Li, Tianming Liu, Wei Liu, Zhengliang Liu, Zhong Liu, Daniel Ma, Samir H. Patel, Guangya Wang, Yunze Yang
Affiliation: University of Miami, Mayo Clinic, School of Data Science, University of Virginia, School of Computing, University of Georgia, Department of Radiation Oncology, Mayo Clinic, Institute of Western China Economic Research, Southwestern University of Finance and Economics
Abstract Preview: Purpose:
Traditional patient outcome analyses relied heavily on conventional statistical models that primarily elucidate correlation rather than causal relationships. In this study, we aim to ident...
Authors: Yu Chang, Mei Chen
Affiliation: Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Abstract Preview: Purpose: Spot weights optimization, as a critical step in the proton therapy, is often time-consuming and labor-intensive. Deep learning, with its powerful learning and computational efficiency, can e...
Authors: Arpit M. Chhabra, J Isabelle Choi, Minglei Kang, Haibo Lin, Hang Qi, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Xingyi Zhao, Ajay Zheng
Affiliation: New York Proton Center, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose:
Pencil beam scanning (PBS) proton therapy effectively treats ocular cancer by minimizing exit doses to normal tissues. However, challenges remain in sparing nearby organs-at-risk(OARs). Ul...
Authors: Alonso N. Gutierrez, Daniel E. Hyer, Blake R. Smith
Affiliation: Miami Cancer Institute, Baptist Health South Florida, Iowa Health Care, University of Iowa
Abstract Preview: Purpose: To perform a feasibility study of optimizing and producing a compact range compensator to deliver single-energy pencil beam scanning (PBS) proton arc therapy treatments. Omitting energy chang...
Authors: Laura Bennett, Wesley S. Culberson, Albert Du, Kevin J. Erhart, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care, .decimal
Abstract Preview: Purpose: To develop and experimentally validate a novel Monte Carlo (MC) framework designed to enable calculation-based quality assurance (QA) for collimated intensity modulated proton therapy treatme...
Authors: Zhitao Dai, Riao Dao, Xuanfeng Ding, Qingkun Fan, Yajun Jia, Gang Liu, Gang Peng, Yujia Qian, Hong Quan, Kunyu Yang, Sheng Zhang, Lewei Zhao
Affiliation: Department of Radiation Oncology, Stanford University, Corewellhealth William Beaumont University Hospital, School of Mathematics and Statistics, Wuhan University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Chinese Academy of Medical Sciences Cancer Hospital Shenzhen Hospital, School of Physics and Technology,Wuhan University, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital， Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: Lattice radiation therapy (LRT) is an innovative three-dimensional(3D) implementation type of spatially fractionated radiation therapy (SFRT). This study aims to develop a novel spot-scanning...
Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Lewei Zhao
Affiliation: Department of Radiation Oncology, Stanford University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital
Abstract Preview: Purpose: This study quantitatively evaluates the interplay effect in intensity-modulated proton therapy (IMPT) for lung cancer stereotactic body radiotherapy (SBRT) using two different machine deliver...
Authors: Grant Evans, Maxwell Arthur Kassel, Charles Shang, Stephen Shang
Affiliation: South Florida Proton Therapy Institute, SFPRF
Abstract Preview: Purpose: Proton pencil beam scanning therapy is particularly sensitive to field translational shifts and beam range variations, which can degradation of dose distribution and compromise the treatment....
Authors: Wenhua Cao, Hadis Moazami Goudarzi, Madison Emily Grayson, Zongsheng Hu, Gino Lim, Steven Hsesheng Lin, Radhe Mohan
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Industrial Engineering, University of Houston, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Proton Arc Therapy (PAT) offers significant potential in treating complex cancer cases by delivering a continuous radiation dose as the gantry rotates. This study aims to investigate the pote...
Authors: Ergun E. Ahunbay, Abdul Parchur, Eric S. Paulson, Ilaria Rinaldi, Angelo Schiavi, Li Zhao
Affiliation: Sapienza University of Rome, Department of Radiation Oncology (Maastro), GROW School for Oncology, Maastricht University Medical Centre+, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Online adaptive replanning is often necessary in Intensity Modulated Proton Therapy (IMPT) due to the sensitivity of proton dose distributions to daily anatomical changes. A rapid, automated ...
Authors: Katja M. Langen, William Andrew LePain, Robert Muiruri, Vivi Nguyen, Mosa Pasha, Roelf L. Slopsema, Alexander Stanforth, Yinan Wang, Mingyao Zhu
Affiliation: Emory Healthcare, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Intensity modulated proton therapy (IMPT) treatment planning for craniospinal irradiation (CSI) is complex and requires extensive effort from the planner. This study aims to enhance planning ...
Authors: Zahra Ahmadi Ganjeh, Stefan Both, Peter Dendooven, Jeffrey Free, Brian Zapien Campos
Affiliation: Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Particle Therapy Research Center (PARTREC), Department of Radiation Oncology, University Medical Center Groningen, University of Groningen
Abstract Preview: Purpose: Positron emission tomography (PET) has been investigated for range monitoring in intensity-modulated proton therapy (IMPT), but real-time feedback been limited due to the focus on long-lived ...
Authors: Yabo Fu, Yang Lei, Yu Lei, Haibo Lin, Ruirui Liu, Tian Liu, Kenneth Rosenzweig, Charles B. Simone, Shouyi Wei, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York Proton Center
Abstract Preview: Purpose: Beam orientation optimization (BOO) in intensity-modulated radiation therapy (IMRT) is traditionally a complex, non-convex problem tackled with heuristic methods. This study benchmarks global...
Authors: Andrew Huang, Jonathan Huang, Andrew S Kennedy, Ellie Grace Kong, Ajay Zheng
Affiliation: New York Proton Center, Centennial Medical Center, Executive Medical Physics Associates, Sarah Cannon Cancer Institute, Belmont University
Abstract Preview: Purpose:
Lung stereotactic body radiotherapy (SBRT) is the standard of care for early-stage lung cancer. Respiratory phase gating can be applied to mitigate motion-induced effects. The purpose of t...
Authors: Austen N. Curcuru, Arash Darafsheh, Winter Green, Yao Hao, Baozhou Sun, Tiezhi Zhang, Tianyu Zhao, Xiandong Zhao
Affiliation: WashU Medicine, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine, Washington University in St. Louis, University of South Florida, Baylor College of Medicine
Abstract Preview: Purpose: Intensity modulated proton therapy (IMPT) requires precise setup imaging due to the sharp dose gradients and rapid distal fall-off seen in proton therapy dose distributions. Additionally, onl...
Authors: Michael Confer, Mark A. Newpower
Affiliation: University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: A pediatric patient recently presented to our clinic for treatment for chordoma, which was near the brainstem. The clinician elected to treat this patient using intensity modulated proton the...
Authors: Tianyuan Dai, Xiaoying Fan, Shuting Wang, Yong Yin
Affiliation: Department of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: The purpose of this study was to investigate the interplay effect during intra-fractional motion and the effect of the robust optimization parameters for inter-fractional motion in the intens...
Authors: Angela Gathers, Christina Henson, Sakuntala Jagabattuni, Mark A. Newpower
Affiliation: University of Oklahoma HSC, Department of Otolaryngology, University of Oklahoma HSC, University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: A previous departmental study showed an increase in ototoxicity (hearing loss) rates in head & neck cancer (HNC) patients treated with Intensity Modulated Proton Therapy (IMPT) vs. x-ray radi...
Authors: Hao Gao, Yuting Lin, Jufri Setianegara, Aoxiang Wang, Peng Xiao, Qingguo Xie, Yanan Zhu
Affiliation: Department of Biomedical Engineering, Huazhong University of Science and Technology, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Intensity-modulated proton therapy (IMPT) achieves uniform tumor dose distribution while sparing organs-at-risk (OAR) by optimizing spot weights across energy layers. Accelerating IMPT delive...
Authors: Kaile Li
Affiliation: Alexander T. Augusta Miliary Medical Center
Abstract Preview: Purpose: To develop a experimental method in observation of beam profile transfer model in intensity modulated radiotherapy (IMRT).
Methods: A picket fence plan was generated in Eclipse treatment p...
Authors: Parker Anderson, Elizabeth L. Bossart, Jonathan Cyriac, Nesrin Dogan, Robert Kaderka, Yihang Xu
Affiliation: University of Miami, University of Miami, Sylvester Comprehensive Cancer Center, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose:
Knowledge-based planning (KBP) can enhance the treatment planning process in cancer radiotherapy (RT). By training a KBP model with high-quality treatment plans developed by experts, dose-...
Authors: Grant Evans, Maxwell Arthur Kassel, Charles Shang, Michael H. Shang, Stephen Shang, Timothy R Williams
Affiliation: South Florida Proton Therapy Institute, SFPRF, Department of Radiation Medicine, MedStar Georgetown University Hospital
Abstract Preview: Purpose:
Daily image guidance for head and neck intensity-modulated proton therapy (IMPT) presents significant challenges due to large target volumes and anatomical changes. Geometric deviations al...
Authors: Sumanta Manna, Atul Mishra, Surendra Prasad Mishra, Kailash Kumar Mittal, Anoop Kumar Srivastava, Neha Yadav
Affiliation: Department of Radiation Oncology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Department of radiation Oncology, Apollomedics Super Speciality Hospitals, Department of Radiation Oncology, Uttar Pradesh University of Medical Sciences, Department of Radiation Oncology, Kalyan Singh Super Specialty Cancer Institute
Abstract Preview: Purpose: This study aimed to assess the dosimetric performance of Volumetric Modulated Arc Therapy (VMAT), step-and-shoot Intensity-Modulated Radiation Therapy (ss-IMRT), and dynamic Intensity-Modulat...
Authors: Yuzhen Ding, Hongying Feng, Jason Michael Holmes, Baoxin Li, Wei Liu, Daniel Ma, Lisa McGee, Samir H. Patel, Jean Claude M. Rwigema, Sujay A. Vora
Affiliation: Arizona State University, Department of Radiation Oncology, Mayo Clinic, Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose:
Intensity-modulated proton therapy (IMPT) is a preferred treatment modality for head and neck (H&N) cancer patients, offering precise tumor targeting while sparing surrounding organs at ri...
Authors: Nan Li, Yaoying Liu, Shouping Xu, Gaolong Zhang
Affiliation: Department of Radiation Oncology, School of Physics, Beihang University, School of physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: In intensity-modulated proton therapy (IMPT) for head and neck cancer, CBCT registration ensures accurate setup, minimizing dose errors. Unlike IMRT, IMPT plans directly define tumor volumes ...
Authors: Mark A. Newpower, Jill Taylor
Affiliation: University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: RayStation 2024A allows planners to optimize intensity modulated proton therapy (IMPT) plans using discrete arcs which can then be converted to traditional pencil beam scanning (PBS) beams fo...
Authors: Stella Flampouri, Edgar Gelover, William Andrew LePain, Roelf L. Slopsema, Alexander Stanforth, Mingyao Zhu
Affiliation: Emory Healthcare, Emory University
Abstract Preview: Purpose: Little consideration was given to the change in dose rate (DR) observed when moving to pencil beam scanning (PBS). This study reports on DR in clinical prostate PBS plans. While dose distribu...
Authors: Chia-Lung Chien, Wen C. Hsi, Romy Megahed, Kayla Schneider
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
The dosimetric variations induced by inter-fractional anatomical changes in intensity-modulated proton therapy could impact the clinic outcomes for head-and-neck (HN) cancer patients. This...
Authors: Ergun E. Ahunbay, Abdul Kareem Parchur, Eric S. Paulson, Ilaria Rinaldi, Angelo Schiavi, Li Zhao
Affiliation: Sapienza University of Rome, Department of Radiation Oncology (Maastro), GROW School for Oncology, Maastricht University Medical Centre+, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Secondary dose calculations (SDC) facilitate patient-specific quality assurance for online adaptive intensity-modulated proton therapy (IMPT). However, there is currently a lack of commercial...
Authors: Bing-Hao Chiang, Eric C. Ford, Juergen Meyer, Timothy D. Solberg
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: This study evaluated the potential risk reduction of various pretreatment patient-specific quality assurance (PSQA) programs for Intensity Modulated Radiation Therapy (IMRT) in mitigating fai...
Authors: Daniela Branco, John M Bryant, Surendra Bahadur Chand, Pratiksha Shahi, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, B.P. Koirala Memorial Cancer Hospital, , B.P Koirala Memorial Cancer Hospital, University of California San Diego / California Protons, Department of Radiation Oncology, Moffitt Cancer Center
Abstract Preview: Purpose:
Cervical cancer remains a significant health burden in Nepal, with 2169 new cases and 1313 deaths recorded in 2022. This study evaluates the feasibility of implementing step-and-shoot IMRT...
Authors: Niels Bassler, Jonathan Bortfeldt, Davide Boscaini, Francesco Evangelista, Guyue Hu, Ze Huang, Margarita Kozak, Julie Lascaud, Giulio Lovatti, Eero Lönnqvist, Jasper Nijkamp, Munetaka Nitta, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Babak Sharifi, Brita Singers Sørensen, Peter Thirolf
Affiliation: Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Ludwig-Maximilians Universität, Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital
Abstract Preview: Purpose: To perform the first in vivo application of a novel small animal radiation research platform combining on-board image-guidance with multi-field intensity modulated spot scanning delivery [1] ...
Authors: Qianyi Xu, Inhwan Yeo
Affiliation: INOVA Schar Cancer Institute, Thomas Jefferson University
Abstract Preview: Purpose:
Four-dimensional computed tomography(4DCT) is prone to a geometrical error when respiration changes upon patient shift. 4DCT with a longer-length detector(16cm), uninvolving the shift, has...
Authors: Shen Fu, Jun Hou, Zuofeng LI, Taize Yuan, Qingyuan Zhang, Yuanshui Zheng
Affiliation: GuangZhou Concord Cancer Center, Guangzhou Concord Cancer Center, 广州泰和肿瘤医院
Abstract Preview: Purpose: A visual feedback system is beneficial for patients to maintain consistent respiratory signal during gated radiotherapy, especially for intensity modulated proton therapy (IMPT) where motion ...
Authors: Omer Gal, Alonso N. Gutierrez, Matthew D. Hall, Rupesh Kotecha, Minesh P. Mehta, Andrew J. Wroe, Jen Yu
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose: Linear energy transfer (LET) is directly related to relative-biological-effectiveness dose in proton therapy. This study aims to investigate how the treatment field hinge angles affect LET of...
Authors: Shen Fu, Zhangmin LI, Zuofeng LI, Yuanshui Zheng
Affiliation: GuangZhou Concord Cancer Center, Guangzhou Concord Cancer Center
Abstract Preview: Purpose: To investigate the influence of different robustness optimization strategies and parameters in proton therapy plans for head and neck tumors on target coverage and OAR (organ at risk) sparing...
Authors: Gregory A Azzam, Michael Butkus, Nesrin Dogan, Robert Kaderka, Nhan Vu, Yihang Xu
Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center, University of Miami, Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Knowledge-based planning (KBP) has demonstrated potential for improving planning quality and efficiency. Adoption of KBP in particle therapy has been slow due to limited number of plans to tr...
Authors: Sina Mossahebi, Pouya Sabouri, Kayla Schneider, James W Snider
Affiliation: University of Maryland School of Medicine, Proton International, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Conventional patient-specific QA (PSQA) for intensity-modulated proton therapy (IMPT) requires extensive measurements, straining resources in single-room proton centers. This study evaluat...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Iowa, Iowa Health Care
Abstract Preview: Purpose:
To perform end-to-end treatment planning and delivery verification of energy-specific collimated treatments optimized to achieve the maximum obtainable high-dose conformity using the dynam...
Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Zi Yang, Kangning Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Delivery efficiency and robustness are critical in spot-scanning proton arc therapy (SPAT), yet the conventional use of redundant energy layers (ELs) prolongs switching times and reduces effi...
Authors: Laurence Edward Court, Alexandra Olivia Leone, Zhongxing Liao, Saurabh Shashikumar Nair, Joshua S. Niedzielski, Ramon Maurilio Salazar, Ting Xu
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Radiation Pneumonitis (RP) predictive models often rely on clinical and DVH parameters, but multiomic features from CT imaging and 3D dose distributions from various regions could provide add...
Authors: Chia-Lung Chien, Wen C. Hsi, Faraz Kalantari, Pouya Sabouri, Man Yam
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose:
Reducing treatment delivery time is critical to improving patient throughput and minimizing the risk of intrafraction motion, which can compromise treatment accuracy. This study identifies...
Authors: Malvern Madondo, Mark McDonald, Zhen Tian, Christopher Valdes, Ralph Weichselbaum, Xiaofeng Yang, David Yu, Jun Zhou
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Chicago, Emory University, Department of Radiology, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Head-and-neck (HN) cancer patients often experience significant anatomical changes during treatment course. Proton therapy, particularly intensity-modulated proton therapy (IMPT), is sensitiv...
Authors: Hao Chen, Kai Ding, Xiaoyu Hu, Xun Jia, Heng Li, Devin Miles
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Accurately delivering radiation dose is critical in intensity-modulated proton therapy (IMPT), where intrafraction motion management plays a pivotal role. Our proton therapy system equipped x...
Authors: Richard Bakst, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Minglei Kang, Nancy Y Lee, Haibo Lin, Hang Qi, Charles B. Simone, Pingfang Tsai, Milo Vermeulen, Shouyi Wei, Xiaodong Wu, Lee Xu, Irini Yacoub, Xingyi Zhao, Ajay Zheng
Affiliation: University of Miami, Peking University, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, icahn school of medicine at mount sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose:
Three-dimensional lattice radiation therapy (3D-LRT) effectively achieves local tumor control with limited morbidity. Pencil beam scanning (PBS) proton therapy provides precise dose confor...
Authors: Julien Bancheri, Chau Giang Bui, David G Cooke, Christopher M Lund, Morgan J Maher, Jan P. Seuntjens, Jason Z Yuan
Affiliation: Princess Margaret Cancer Centre & University of Toronto, Medical Biophysics, University of Toronto, University of Toronto, Medical Physics Unit, McGill University, Department of Physics, McGill University
Abstract Preview: Purpose: The dielectric wall accelerator (DWA) offers a low-cost solution for proton therapy, using non-resonant waveguides to accelerate particles. Radial waveguides (RWGs), consisting of a dielectri...
Authors: Xiu tong Lin
Affiliation: Department of Radiation physics and technology, Shandong Second Provincial General Hospital
Abstract Preview: Purpose: To compare the dosimetric differences between the photon and proton plans and between the different target according to the placement of the implants for patients undergoing radiotherapy afte...
Authors: Yujie Chi, Yao Hao, Xun Jia, Youfang Lai, Yuting Peng, Francisco Javier Reynoso, Lingshu Yin, Tianyu Zhao, Xiandong Zhao
Affiliation: Johns Hopkins University, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Physics, University of Texas at Arlington, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, University of South Florida
Abstract Preview: Purpose: FLASH radiation therapy has shown remarkable tissue sparing effects compared to radiation therapy at conventional dose rates (CDR). Yet, its mechanism remains unclear. Radical production modu...
Authors: Eric S. Diffenderfer, Lei Dong, Alejandro Garcia, Wenbo Gu, Michele M. Kim, Alexander Lin, Kai Mei, Peter B. Noël, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: We present a novel 3D-printed range-modulating devices with spatially modulated density for FLASH particle therapy. By varying density distributions, spread-out Bragg peaks(SOBPs) can be gene...
Authors: Chingyun Cheng, Ben Durkee, Carri K. Glide-Hurst, Minglei Kang, Haibo Lin, Bhudatt R. Paliwal, Charles B. Simone, Zhizhen Wei, Tengda Zhang, Xingyi Zhao
Affiliation: University of Wisconsin, Department of Mechanical Engineering, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Transmission Beam (TB), Single-Energy Bragg Peak (SEBP), and Single-Energy Spread-Out Bragg Peak (SESOBP) are primary proton conformal FLASH techniques. However, each comes with significant l...
Authors: Kenny Guida, Daniel Johnson, Wesley Tucker
Affiliation: University of Kansas Medical Center, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Intensity modulated proton therapy (IMPT) has emerged as a standard of care for unilateral head and neck (HN) cancers due to superior OAR sparing. With the increase of proton centers national...