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Results for "monitoring tissue": 21 found

Advanced Daily Imaging Technology Improves Tracking of Soft Tissue Decomposition for Head and Neck Cancer Patients Receiving Radiotherapy

Authors: Robert K Chin, Klea Hoxha, Erika Jank, Jesus Juarez, Eulanca Yuka Liu, Dylan P. O'Connell, X. Sharon Qi, Ricky R Savjani

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, Los Angeles, UCLA Radiation Oncology

Abstract Preview: Purpose:
Daily cone beam CT (CBCT) images are acquired prior to each radiotherapy treatment for verifying patient positioning. HyperSight is an advanced imaging solution that replaces standard CBCT...

Assessment of Viscoelastic Changes in Ex Vivo Liver Tissue Using Pulsed Magnetomotive Ultrasound during Magnetic Hyperthermia

Authors: David Alejandro Collazos Burbano, Antonio Adilton Oliveira Carneiro, Paul L. Carson, Jose Eduardo Freire, Theo Zeferino Pavan, Joao Henrique Uliana, Nicholas Zufelato

Affiliation: University of São Paulo, University of Michigan, University of Sao Paulo

Abstract Preview: Purpose: Develop a theranostic platform that integrates magnetic hyperthermia (MH), ultrasound, and magnetic nanoparticles (MNPs) to improve diagnosis, treatment, and monitoring of hyperthermia proced...

Automating Radiographic Sharp Score Prediction in Rheumatoid Arthritis Using Multistage Deep Learning Methods

Authors: Hajar Moradmand, Lei Ren

Affiliation: University of Maryland School of Medicine, University of Maryland

Abstract Preview: Purpose:
The Sharp-van der Heijde (SvH) score is essential for assessing joint damage in rheumatoid arthritis (RA) from radiographic images. However, manual scoring is time-intensive and prone to v...

Breathing New Life into Pulmonary Imaging: Development and Clinical Validation of an X-Ray Interferometry System

Authors: Rachael Blair, Les Butler, Lillian Dickson, Kyungmin Ham, Charles Hartman, Kenneth (Kip) Matthews, Corinne Vanya

Affiliation: Louisiana State University, University of Minnesota, Refined Imaging LLC, Center for Advanced Microstructures and Devices

Abstract Preview: Purpose:
To develop and evaluate an x-ray interferometry system (XIS) for low-dose, high-sensitivity diagnostic imaging of lung diseases such as chronic obstructive pulmonary disease (COPD), asthma...

Comparison of Multispectral Singlet Oxygen Luminescent Dosimetry (MSOLD) and Singlet Oxygen Explicit Dosimetry (SOED) in BPD-Mediated PDT for Mice

Authors: Robert H Hadfield, Madelyn Johnson, Baozhu Lu, Hongjing Sun, Vikas Vikas, Brian C. Wilson, Weibing Yang, Timothy C. Zhu

Affiliation: University of Glasgow, University of Toronto, University of Pennsylvania

Abstract Preview: Purpose:
Multispectral Singlet Oxygen Luminescent Dosimetry (MSOLD) has been developed as a real-time in vivo dosimetry technique for Photodynamic Therapy (PDT). This study investigates the feasibi...

Dynamic X-Ray Acoustic Computed Tomography (XACT)

Authors: Leshan Sun, Liangzhong Xiang, Yifei Xu, Yuchen Yan

Affiliation: University of California, Irvine

Abstract Preview: Purpose: X-ray Acoustic Computed Tomography (XACT) is a transformative innovation in medical imaging, overcoming the limitations of conventional X-ray techniques. It introduces new possibilities in cl...

Enhancing Image Quality in Acoustic Imaging Using the Segment Anything Model (SAM)

Authors: Jadon Buller, Zhuoran Jiang, Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu

Affiliation: University of Maryland School of Medicine, University of California, Irvine, University of California, Stanford University

Abstract Preview: Purpose: Electroacoustic tomography (EAT) and Protoacoustic (PA) imaging are novel modalities for treatment verification of electroporation and proton therapy. However, the limited acquisition angle i...

Four-Dimensional on-Beam Computed Tomography Reconstruction from Projection Image Differences Representing Motion Change

Authors: Kwang-Ho Cheong, Seungryong Cho, Joonil Hwang, Jae Won Jung, Hoyeon Lee, Raymond Hyunwoo Moon, Inhwan Yeo, Jihyung Yoon

Affiliation: East Carolina University, INOVA Schar Cancer Institute, University of Hong Kong, Hanllym University, KAIST, University of Rochester

Abstract Preview: Purpose: Monitoring a target and neighboring organs during beam delivery is crucial for successful radiotherapy (RT). Conventional transit imaging methods lack volumetric reconstruction capabilities, ...

Imaging Preclinical Proton Flash Radiation Using a Small Animal PET System

Authors: Xun Jia, Heng Li, Wen Li, Devin Miles, Daniel Sforza, Lingshu Yin, Yuncheng Zhong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: FLASH therapy holds great potential to revolutionize radiotherapy by minimizing toxicities of normal tissues. The extraordinarily high dose rate of FLASH proton beam makes precise delivery to...

Inter-Fraction Monitoring of Brain Metastases Resection Cavities during Fractionated Stereotactic Radiosurgery on the 0.35 T MRI-Linac

Authors: Eyub Y. Akdemir, Gregory A Azzam, Rupesh Kotecha, Gregory J. Kubicek, Natalia Lutsik, Eric Mellon, Siamak P. Nejad-Davarani, Parag Parikh, Karen C. Snyder

Affiliation: Miami Cancer Institute, Baptist Health South Florida, Department of Radiation Oncology, University of Miami, Henry Ford Health

Abstract Preview: Purpose: Resection cavity volumes shrink gradually over time after surgical resection of brain metastases. Fractionated stereotactic radiosurgery (fSRS) is often delivered to the cavity to prevent rec...

Matching CT Numbers between a Photon-Counting CT and an Energy-Integrating Detector CT: A Phantom Study

Authors: Afrouz Ataei, Xinhui Duan, Mi-Ae Park, Liqiang Ren

Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University

Abstract Preview: Purpose:
Photon-counting CT (PCCT) has become commercially available recently, offering significant potential to enhance patient care. However, it also introduces unique challenges. One such challe...

Minimizing Abscopal Effects in Normal Tissues with Flash-RT: Mechanisms of Action and Potential Clinical Applications

Authors: Liang Cui, Xingyu Lu, Hang Shang, LingHong Zhou

Affiliation: Southern Medical University

Abstract Preview: Purpose: This study examines how varying dose rates of radiotherapy impact normal tissues outside the target area and analyzes the protective effects and regulatory mechanisms of ultra-high dose rate ...

Motion Correction-Driven Patient-Specific 2D Cine MRI-Based Dynamic Volumetric Reconstruction for MRI-Guided Radiotherapy Intra-Fractional Motion Monitoring

Authors: Karyn A Goodman, Yang Lei, Tian Liu, D. Michael Lovelock, Charlotte Elizabeth Read, Jing Wang, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai

Abstract Preview: Purpose: Real-time volumetric MRI is essential for precise motion management in MRI-guided radiotherapy (MRIgRT). While 2D Cine MRI offers high temporal resolution for motion tracking, it inherently l...

Non-Contact Electroacoustic Imaging Monitoring Electroporation Therapy

Authors: Zhongping Chen, Yuchen Song, Leshan Sun, Liangzhong Xiang, Yifei Xu

Affiliation: University of California, Irvine, University of California Irvine

Abstract Preview: Purpose: Electroacoustic tomography (EAT) monitors the distribution of electrical energy in tissues by detecting acoustics signals induced by electrical pulses during irreversible electroporation (IRE...

Non-Invasive Photoacoustic Thermometry for Real-Time Monitoring of Tissue Temperature Using Frequency Analysis

Authors: Hisham Assi, Lexi Dowdy, Muhannad N. Fadhel, Michael C. Kolios, Carl Kumaradas, Rasha S Makkia, Tanay N Mannikar

Affiliation: Toronto Metropolitan University, Augusta University, Institute for Biomedical Engineering, Science and Technology (iBEST), Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Northwestern University, Medical College of Georgia, Augusta University

Abstract Preview: Introduction: Hyperthermia is an emerging strategy for cancer treatment due to its few side effects and low cost. Hyperthermia is used in conjunction with other treatments, such as radiation therapy, ...

Phase One Randomized Two-Arm Dose Escalation of Flash RT in Veterinary Canine Osteosarcoma: Trial Design & Initial Results

Authors: Wesley S. Culberson, Aleksandra Ilina, Brian W Pogue, Matthew Reed, Connor Strainis, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel

Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin–Madison, University of Wisconsin-Madison, University of Wisconsin - Madison

Abstract Preview: Purpose: FLASH radiotherapy reduces skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR), while preserving damage to tumor tissue. The FLASH effec...

Radio-Acoustic Monitoring of Electron Flash Therapy In Vivo

Authors: Kristina Bjegovic, Luke Connell, Emil Schueler, Leshan Sun, Lucy Whitmore, Liangzhong Xiang

Affiliation: University of California, Irvine, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: The use of FLASH-RT in the clinic would greatly reduce off-target radiation toxicity in normal tissues. However, due to the hypo-fractionated delivery of prescribed doses at FLASH dose rates,...

Real-Time 3D Visualization of Electric Field with Electroacoustic Tomography

Authors: Jadon O Buller, Yankun Lang, Liangzhong Xiang, Andrea Paulina Yanez

Affiliation: University of Maryland School of Medicine, University of California, Irvine

Abstract Preview: Purpose: With the widespread adoption of electroporation, there is growing interest in deep-tissue electric field monitoring. Electroporation therapy ablates target regions by generating electric fiel...

Real-Time Output Gating and Fault Handling for an Uhdr Mobetron

Authors: Petr Bruza, David J. Gladstone, Lesley A Jarvis, Austin Sloop, Kevin J. Willy, Rongxiao Zhang

Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health

Abstract Preview: Purpose:
Active beam monitoring and output-gated dosimetry are essential systems for safe and accurate radiation delivery. UHDR irradiators such as the Mobetron rely on pre-programmed regimes and t...

Repeatability of Quantitative 3D T1ρ Imaging in Head and Neck Cancer

Authors: Sandeep Panwar Jogi, Nancy Lee, Ricardo Otazo, Ramesh Paudyal, Qi Peng, Akash Shah, Amita Shukla-Dave, Can Wu

Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center

Abstract Preview: Purpose: Quantitative T1ρ imaging provides enhanced tissue characterization beyond standard T1 and T2 parameters, potentially supporting early-stage longitudinal monitoring of head and neck cancer. Th...

Validation of Synthetic CT-Based Online Monitoring for Adaptive Proton Therapy

Authors: Ozgur Ates, Chin-Cheng Chen, Chia-Ho Hua, Matthew J. Krasin, Thomas E. Merchant

Affiliation: St. Jude Children's Research Hospital

Abstract Preview: Purpose: To validate the use of synthetic CTs generated from CBCT images for online monitoring, ensuring accurate and reliable daily plan quality assessments in adaptive proton therapy (APT).
Metho...