Authors: Robert K Chin, Klea Hoxha, Erika Jank, Jesus Juarez, Eulanca Yuka Liu, Dylan P. O'Connell, X. Sharon Qi, Ricky R Savjani
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, Los Angeles, UCLA Radiation Oncology
Abstract Preview: Purpose:
Daily cone beam CT (CBCT) images are acquired prior to each radiotherapy treatment for verifying patient positioning. HyperSight is an advanced imaging solution that replaces standard CBCT...
Authors: David Alejandro Collazos Burbano, Antonio Adilton Oliveira Carneiro, Paul L. Carson, Jose Eduardo Freire, Theo Zeferino Pavan, Joao Henrique Uliana, Nicholas Zufelato
Affiliation: University of São Paulo, University of Michigan, University of Sao Paulo
Abstract Preview: Purpose: Develop a theranostic platform that integrates magnetic hyperthermia (MH), ultrasound, and magnetic nanoparticles (MNPs) to improve diagnosis, treatment, and monitoring of hyperthermia proced...
Authors: Hajar Moradmand, Lei Ren
Affiliation: University of Maryland School of Medicine, University of Maryland
Abstract Preview: Purpose:
The Sharp-van der Heijde (SvH) score is essential for assessing joint damage in rheumatoid arthritis (RA) from radiographic images. However, manual scoring is time-intensive and prone to v...
Authors: Rachael Blair, Les Butler, Lillian Dickson, Kyungmin Ham, Charles Hartman, Kenneth (Kip) Matthews, Corinne Vanya
Affiliation: Louisiana State University, University of Minnesota, Refined Imaging LLC, Center for Advanced Microstructures and Devices
Abstract Preview: Purpose:
To develop and evaluate an x-ray interferometry system (XIS) for low-dose, high-sensitivity diagnostic imaging of lung diseases such as chronic obstructive pulmonary disease (COPD), asthma...
Authors: Robert H Hadfield, Madelyn Johnson, Baozhu Lu, Hongjing Sun, Vikas Vikas, Brian C. Wilson, Weibing Yang, Timothy C. Zhu
Affiliation: University of Glasgow, University of Toronto, University of Pennsylvania
Abstract Preview: Purpose:
Multispectral Singlet Oxygen Luminescent Dosimetry (MSOLD) has been developed as a real-time in vivo dosimetry technique for Photodynamic Therapy (PDT). This study investigates the feasibi...
Authors: Leshan Sun, Liangzhong Xiang, Yifei Xu, Yuchen Yan
Affiliation: University of California, Irvine
Abstract Preview: Purpose: X-ray Acoustic Computed Tomography (XACT) is a transformative innovation in medical imaging, overcoming the limitations of conventional X-ray techniques. It introduces new possibilities in cl...
Authors: Jadon Buller, Zhuoran Jiang, Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu
Affiliation: University of Maryland School of Medicine, University of California, Irvine, University of California, Stanford University
Abstract Preview: Purpose: Electroacoustic tomography (EAT) and Protoacoustic (PA) imaging are novel modalities for treatment verification of electroporation and proton therapy. However, the limited acquisition angle i...
Authors: Kwang-Ho Cheong, Seungryong Cho, Joonil Hwang, Jae Won Jung, Hoyeon Lee, Raymond Hyunwoo Moon, Inhwan Yeo, Jihyung Yoon
Affiliation: East Carolina University, INOVA Schar Cancer Institute, University of Hong Kong, Hanllym University, KAIST, University of Rochester
Abstract Preview: Purpose: Monitoring a target and neighboring organs during beam delivery is crucial for successful radiotherapy (RT). Conventional transit imaging methods lack volumetric reconstruction capabilities, ...
Authors: Xun Jia, Heng Li, Wen Li, Devin Miles, Daniel Sforza, Lingshu Yin, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: FLASH therapy holds great potential to revolutionize radiotherapy by minimizing toxicities of normal tissues. The extraordinarily high dose rate of FLASH proton beam makes precise delivery to...
Authors: Eyub Y. Akdemir, Gregory A Azzam, Rupesh Kotecha, Gregory J. Kubicek, Natalia Lutsik, Eric Mellon, Siamak P. Nejad-Davarani, Parag Parikh, Karen C. Snyder
Affiliation: Miami Cancer Institute, Baptist Health South Florida, Department of Radiation Oncology, University of Miami, Henry Ford Health
Abstract Preview: Purpose: Resection cavity volumes shrink gradually over time after surgical resection of brain metastases. Fractionated stereotactic radiosurgery (fSRS) is often delivered to the cavity to prevent rec...
Authors: Afrouz Ataei, Xinhui Duan, Mi-Ae Park, Liqiang Ren
Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University
Abstract Preview: Purpose:
Photon-counting CT (PCCT) has become commercially available recently, offering significant potential to enhance patient care. However, it also introduces unique challenges. One such challe...
Authors: Liang Cui, Xingyu Lu, Hang Shang, LingHong Zhou
Affiliation: Southern Medical University
Abstract Preview: Purpose: This study examines how varying dose rates of radiotherapy impact normal tissues outside the target area and analyzes the protective effects and regulatory mechanisms of ultra-high dose rate ...
Authors: Karyn A Goodman, Yang Lei, Tian Liu, D. Michael Lovelock, Charlotte Elizabeth Read, Jing Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose: Real-time volumetric MRI is essential for precise motion management in MRI-guided radiotherapy (MRIgRT). While 2D Cine MRI offers high temporal resolution for motion tracking, it inherently l...
Authors: Zhongping Chen, Yuchen Song, Leshan Sun, Liangzhong Xiang, Yifei Xu
Affiliation: University of California, Irvine, University of California Irvine
Abstract Preview: Purpose: Electroacoustic tomography (EAT) monitors the distribution of electrical energy in tissues by detecting acoustics signals induced by electrical pulses during irreversible electroporation (IRE...
Authors: Hisham Assi, Lexi Dowdy, Muhannad N. Fadhel, Michael C. Kolios, Carl Kumaradas, Rasha S Makkia, Tanay N Mannikar
Affiliation: Toronto Metropolitan University, Augusta University, Institute for Biomedical Engineering, Science and Technology (iBEST), Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Northwestern University, Medical College of Georgia, Augusta University
Abstract Preview: Introduction: Hyperthermia is an emerging strategy for cancer treatment due to its few side effects and low cost. Hyperthermia is used in conjunction with other treatments, such as radiation therapy, ...
Authors: Wesley S. Culberson, Aleksandra Ilina, Brian W Pogue, Matthew Reed, Connor Strainis, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel
Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin–Madison, University of Wisconsin-Madison, University of Wisconsin - Madison
Abstract Preview: Purpose: FLASH radiotherapy reduces skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR), while preserving damage to tumor tissue. The FLASH effec...
Authors: Kristina Bjegovic, Luke Connell, Emil Schueler, Leshan Sun, Lucy Whitmore, Liangzhong Xiang
Affiliation: University of California, Irvine, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: The use of FLASH-RT in the clinic would greatly reduce off-target radiation toxicity in normal tissues. However, due to the hypo-fractionated delivery of prescribed doses at FLASH dose rates,...
Authors: Jadon O Buller, Yankun Lang, Liangzhong Xiang, Andrea Paulina Yanez
Affiliation: University of Maryland School of Medicine, University of California, Irvine
Abstract Preview: Purpose: With the widespread adoption of electroporation, there is growing interest in deep-tissue electric field monitoring. Electroporation therapy ablates target regions by generating electric fiel...
Authors: Petr Bruza, David J. Gladstone, Lesley A Jarvis, Austin Sloop, Kevin J. Willy, Rongxiao Zhang
Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health
Abstract Preview: Purpose:
Active beam monitoring and output-gated dosimetry are essential systems for safe and accurate radiation delivery. UHDR irradiators such as the Mobetron rely on pre-programmed regimes and t...
Authors: Sandeep Panwar Jogi, Nancy Lee, Ricardo Otazo, Ramesh Paudyal, Qi Peng, Akash Shah, Amita Shukla-Dave, Can Wu
Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center
Abstract Preview: Purpose: Quantitative T1ρ imaging provides enhanced tissue characterization beyond standard T1 and T2 parameters, potentially supporting early-stage longitudinal monitoring of head and neck cancer. Th...
Authors: Ozgur Ates, Chin-Cheng Chen, Chia-Ho Hua, Matthew J. Krasin, Thomas E. Merchant
Affiliation: St. Jude Children's Research Hospital
Abstract Preview: Purpose: To validate the use of synthetic CTs generated from CBCT images for online monitoring, ensuring accurate and reliable daily plan quality assessments in adaptive proton therapy (APT).
Metho...